Page last updated: 2024-10-19

malonic acid and Parkinsonian Disorders

malonic acid has been researched along with Parkinsonian Disorders in 3 studies

malonic acid : An alpha,omega-dicarboxylic acid in which the two carboxy groups are separated by a single methylene group.
dicarboxylic acid : Any carboxylic acid containing two carboxy groups.

Parkinsonian Disorders: A group of disorders which feature impaired motor control characterized by bradykinesia, MUSCLE RIGIDITY; TREMOR; and postural instability. Parkinsonian diseases are generally divided into primary parkinsonism (see PARKINSON DISEASE), secondary parkinsonism (see PARKINSON DISEASE, SECONDARY) and inherited forms. These conditions are associated with dysfunction of dopaminergic or closely related motor integration neuronal pathways in the BASAL GANGLIA.

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's3 (100.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Alfinito, PD1
Wang, SP1
Manzino, L1
Rijhsinghani, S1
Zeevalk, GD1
Sonsalla, PK1
Klivenyi, P2
Starkov, AA1
Calingasan, NY1
Gardian, G2
Browne, SE1
Yang, L2
Bubber, P1
Gibson, GE1
Patel, MS1
Beal, MF2
Siwek, D1
Starkov, A1
Cleren, C1
Ferrante, RJ1
Kowall, NW1
Abeliovich, A1

Other Studies

3 other studies available for malonic acid and Parkinsonian Disorders

ArticleYear
Adenosinergic protection of dopaminergic and GABAergic neurons against mitochondrial inhibition through receptors located in the substantia nigra and striatum, respectively.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2003, Nov-26, Volume: 23, Issue:34

    Topics: Adenosine; Adenosine A1 Receptor Antagonists; Adenosine A2 Receptor Antagonists; Animals; Corpus Str

2003
Mice deficient in dihydrolipoamide dehydrogenase show increased vulnerability to MPTP, malonate and 3-nitropropionic acid neurotoxicity.
    Journal of neurochemistry, 2004, Volume: 88, Issue:6

    Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Caudate Nucleus; Cell Count; Cerebral Cortex;

2004
Mice lacking alpha-synuclein are resistant to mitochondrial toxins.
    Neurobiology of disease, 2006, Volume: 21, Issue:3

    Topics: alpha-Synuclein; Animals; Malonates; Mice; Mice, Mutant Strains; Mitochondria; Neurons; Neurotoxins;

2006