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malonic acid and Neurodegenerative Diseases

malonic acid has been researched along with Neurodegenerative Diseases in 4 studies

malonic acid : An alpha,omega-dicarboxylic acid in which the two carboxy groups are separated by a single methylene group.
dicarboxylic acid : Any carboxylic acid containing two carboxy groups.

Neurodegenerative Diseases: Hereditary and sporadic conditions which are characterized by progressive nervous system dysfunction. These disorders are often associated with atrophy of the affected central or peripheral nervous system structures.

Research Excerpts

ExcerptRelevanceReference
"Coenzyme Q10 is an essential cofactor of the electron transport chain and is an antioxidant."5.30Coenzyme Q10 in the central nervous system and its potential usefulness in the treatment of neurodegenerative diseases. ( Beal, MF; Matthews, RT, 1997)
"Coenzyme Q10 is an essential cofactor of the electron transport chain and is an antioxidant."1.30Coenzyme Q10 in the central nervous system and its potential usefulness in the treatment of neurodegenerative diseases. ( Beal, MF; Matthews, RT, 1997)

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (25.00)18.2507
2000's3 (75.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Klivenyi, P2
Starkov, AA1
Calingasan, NY1
Gardian, G1
Browne, SE1
Yang, L1
Bubber, P1
Gibson, GE1
Patel, MS1
Beal, MF3
Matthews, RT1
Andreassen, OA1
Ferrante, RJ1
Dedeoglu, A1
Albers, DW1
Carlson, EJ1
Epstein, CJ1
Van Westerlaak, MG1
Joosten, EA1
Gribnau, AA1
Cools, AR1
Bär, PR1

Other Studies

4 other studies available for malonic acid and Neurodegenerative Diseases

ArticleYear
Mice deficient in dihydrolipoamide dehydrogenase show increased vulnerability to MPTP, malonate and 3-nitropropionic acid neurotoxicity.
    Journal of neurochemistry, 2004, Volume: 88, Issue:6

    Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Caudate Nucleus; Cell Count; Cerebral Cortex;

2004
Coenzyme Q10 in the central nervous system and its potential usefulness in the treatment of neurodegenerative diseases.
    Molecular aspects of medicine, 1997, Volume: 18 Suppl

    Topics: Administration, Oral; Animals; Antioxidants; Brain; Coenzymes; Corpus Striatum; Electron Transport;

1997
Mice with a partial deficiency of manganese superoxide dismutase show increased vulnerability to the mitochondrial toxins malonate, 3-nitropropionic acid, and MPTP.
    Experimental neurology, 2001, Volume: 167, Issue:1

    Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 3,4-Dihydroxyphenylacetic Acid; Animals; Carrier Prote

2001
Chronic mitochondrial inhibition induces glutamate-mediated corticomotoneuron death in an organotypic culture model.
    Experimental neurology, 2001, Volume: 167, Issue:2

    Topics: Animals; Antigens, Differentiation; Cell Death; Cell Size; Cells, Cultured; Cerebral Cortex; Dizocil

2001