malonic acid has been researched along with Encephalopathy, Toxic in 3 studies
malonic acid : An alpha,omega-dicarboxylic acid in which the two carboxy groups are separated by a single methylene group.
dicarboxylic acid : Any carboxylic acid containing two carboxy groups.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Malonic acid is a reversible inhibitor of mitochondrial enzyme complex-II, induces energy crisis and free radical generation." | 1.72 | Protective effect of 3-n-butylphthalide against intrastriatal injection of malonic acid-induced neurotoxicity and biochemical alteration in rats. ( Yuan, C; Zhao, Y; Zheng, L, 2022) |
| "Quinolinic acid has been reported to induce excitotoxicity by stimulating the N-methyl-D-aspartate receptor, causing calcium overload which in turn leads to the neurodegeneration." | 1.36 | Protective effect of montelukast against quinolinic acid/malonic acid induced neurotoxicity: possible behavioral, biochemical, mitochondrial and tumor necrosis factor-α level alterations in rats. ( Kalonia, H; Kumar, A; Kumar, P; Nehru, B, 2010) |
| "Minocycline has been shown to exert neuroprotection against a wide variety of toxic insults both in vitro and in vivo." | 1.33 | In vivo studies on the protective role of minocycline against excitotoxicity caused by malonate or N-methyl-d-aspartate. ( Aguirre, N; Goñi-Allo, B; Jordán, J; Ramos, M, 2005) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (33.33) | 29.6817 |
| 2010's | 1 (33.33) | 24.3611 |
| 2020's | 1 (33.33) | 2.80 |
| Authors | Studies |
|---|---|
| Yuan, C | 1 |
| Zheng, L | 1 |
| Zhao, Y | 1 |
| Kalonia, H | 1 |
| Kumar, P | 1 |
| Kumar, A | 1 |
| Nehru, B | 1 |
| Goñi-Allo, B | 1 |
| Ramos, M | 1 |
| Jordán, J | 1 |
| Aguirre, N | 1 |
3 other studies available for malonic acid and Encephalopathy, Toxic
| Article | Year |
|---|---|
Protective effect of 3-n-butylphthalide against intrastriatal injection of malonic acid-induced neurotoxicity and biochemical alteration in rats.
Topics: Animals; beta Catenin; Huntington Disease; Nerve Growth Factors; Neuroprotective Agents; Neurotoxici | 2022 |
Protective effect of montelukast against quinolinic acid/malonic acid induced neurotoxicity: possible behavioral, biochemical, mitochondrial and tumor necrosis factor-α level alterations in rats.
Topics: Acetates; Analysis of Variance; Animals; Behavior, Animal; Body Weight; Brain; Brain Chemistry; Cata | 2010 |
In vivo studies on the protective role of minocycline against excitotoxicity caused by malonate or N-methyl-d-aspartate.
Topics: Animals; Dizocilpine Maleate; Drug Administration Routes; Drug Administration Schedule; Male; Malona | 2005 |