malonic acid has been researched along with Amyotrophic Lateral Sclerosis in 2 studies
malonic acid : An alpha,omega-dicarboxylic acid in which the two carboxy groups are separated by a single methylene group.
dicarboxylic acid : Any carboxylic acid containing two carboxy groups.
Amyotrophic Lateral Sclerosis: A degenerative disorder affecting upper MOTOR NEURONS in the brain and lower motor neurons in the brain stem and SPINAL CORD. Disease onset is usually after the age of 50 and the process is usually fatal within 3 to 6 years. Clinical manifestations include progressive weakness, atrophy, FASCICULATION, hyperreflexia, DYSARTHRIA, dysphagia, and eventual paralysis of respiratory function. Pathologic features include the replacement of motor neurons with fibrous ASTROCYTES and atrophy of anterior SPINAL NERVE ROOTS and corticospinal tracts. (From Adams et al., Principles of Neurology, 6th ed, pp1089-94)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Diao, ZY | 1 |
| Shen, Y | 1 |
| Fan, DS | 1 |
| Zheng, M | 1 |
| Cui, JY | 1 |
| Sun, AP | 1 |
| Song, DM | 1 |
| Fan, SG | 1 |
| Kaal, EC | 1 |
| Vlug, AS | 1 |
| Versleijen, MW | 1 |
| Kuilman, M | 1 |
| Joosten, EA | 1 |
| Bär, PR | 1 |
2 other studies available for malonic acid and Amyotrophic Lateral Sclerosis
| Article | Year |
|---|---|
[Establishment of the organotypic model of amyotrophic lateral sclerosis from the SD rats' spinal cord].
Topics: Amyotrophic Lateral Sclerosis; Animals; Animals, Newborn; Cells, Cultured; Disease Models, Animal; M | 2005 |
Chronic mitochondrial inhibition induces selective motoneuron death in vitro: a new model for amyotrophic lateral sclerosis.
Topics: Adenosine Triphosphate; Amyotrophic Lateral Sclerosis; Animals; Cell Survival; Cells, Cultured; Dise | 2000 |