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malonic acid and Aging

malonic acid has been researched along with Aging in 9 studies

malonic acid : An alpha,omega-dicarboxylic acid in which the two carboxy groups are separated by a single methylene group.
dicarboxylic acid : Any carboxylic acid containing two carboxy groups.

Aging: The gradual irreversible changes in structure and function of an organism that occur as a result of the passage of time.

Research Excerpts

ExcerptRelevanceReference
"Transgenic Huntington's disease (HD) mice, expressing exon 1 of the HD gene with an expanded CAG repeat, are totally resistant to striatal lesion induced by excessive NMDA receptor activation."1.31Partial resistance to malonate-induced striatal cell death in transgenic mouse models of Huntington's disease is dependent on age and CAG repeat length. ( Bates, GP; Brundin, P; Castilho, RF; Hansson, O; Korhonen, L; Lindholm, D, 2001)

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19903 (33.33)18.7374
1990's3 (33.33)18.2507
2000's3 (33.33)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Kölker, S1
Schwab, M1
Hörster, F1
Sauer, S1
Hinz, A1
Wolf, NI1
Mayatepek, E1
Hoffmann, GF1
Smeitink, JA1
Okun, JG1
JILEK, L1
TROJAN, S1
Mitzen, EJ1
Koeppen, AH2
Beal, MF1
Brouillet, E1
Jenkins, B1
Henshaw, R1
Rosen, B1
Hyman, BT1
Meldrum, A1
Page, KJ1
Everitt, BJ1
Dunnett, SB1
Hansson, O1
Castilho, RF1
Korhonen, L1
Lindholm, D1
Bates, GP1
Brundin, P1
Riley, KM1
Dickson, AC1
Jena, BS1
Patnaik, BK1
Ando, M1
Itoh, T1

Other Studies

9 other studies available for malonic acid and Aging

ArticleYear
Methylmalonic acid, a biochemical hallmark of methylmalonic acidurias but no inhibitor of mitochondrial respiratory chain.
    The Journal of biological chemistry, 2003, Nov-28, Volume: 278, Issue:48

    Topics: Acyl Coenzyme A; Adenosine Triphosphate; Aging; Amino Acid Metabolism, Inborn Errors; Animals; Cattl

2003
[EFFECT OF SODIUM MALONATE AND MONOIODACETIC ACID ON THE RESISTANCE OF RATS TO OLIGEMIA OF THE CENTRAL NERVOUS SYSTEM DURING THE COURSE OF ONTOGENESIS].
    Sbornik lekarsky, 1963, Volume: 65

    Topics: Adaptation, Physiological; Aging; Animals; Animals, Newborn; Carotid Arteries; Central Nervous Syste

1963
Malonate, malonyl-coenzyme A, and acetyl-coenzyme A in developing rat brain.
    Journal of neurochemistry, 1984, Volume: 43, Issue:2

    Topics: Acetyl Coenzyme A; Acyl Coenzyme A; Aging; Animals; Bacterial Proteins; Brain; Carboxy-Lyases; Coenz

1984
Age-dependent striatal excitotoxic lesions produced by the endogenous mitochondrial inhibitor malonate.
    Journal of neurochemistry, 1993, Volume: 61, Issue:3

    Topics: Adenosine Triphosphate; Aging; Animals; Corpus Striatum; Dizocilpine Maleate; gamma-Aminobutyric Aci

1993
Age-dependence of malonate-induced striatal toxicity.
    Experimental brain research, 2000, Volume: 134, Issue:3

    Topics: Aging; Animals; Animals, Newborn; Brain Diseases; Cell Death; Corpus Striatum; Drug Resistance; Elec

2000
Partial resistance to malonate-induced striatal cell death in transgenic mouse models of Huntington's disease is dependent on age and CAG repeat length.
    Journal of neurochemistry, 2001, Volume: 78, Issue:4

    Topics: Aging; Amino Acid Chloromethyl Ketones; Animals; bcl-X Protein; Blood Glucose; Cell Death; Corpus St

2001
The origin of free brain malonate.
    Neurochemical research, 1991, Volume: 16, Issue:2

    Topics: Acetates; Acetic Acid; Acetyl Coenzyme A; Aging; Animals; Brain; Butyrates; Butyric Acid; Carbon Rad

1991
Effect of malonate and p-chlorophenoxy acetic acid on hepatic succinic dehydrogenase activity of ageing lizards.
    Gerontology, 1990, Volume: 36, Issue:1

    Topics: Aging; Animals; Enzyme Inhibitors; Glycolates; In Vitro Techniques; Liver; Lizards; Male; Malonates;

1990
Changes of amino acid by the deprivation of energy sources in the cerebral cortex.
    Brain & development, 1989, Volume: 11, Issue:3

    Topics: 3-Hydroxybutyric Acid; Aging; Amino Acids; Animals; Cerebral Cortex; Energy Metabolism; Female; Hydr

1989