Page last updated: 2024-08-21

malondialdehyde and Parkinson Disease

malondialdehyde has been researched along with Parkinson Disease in 65 studies

Research

Studies (65)

TimeframeStudies, this research(%)All Research%
pre-19902 (3.08)18.7374
1990's6 (9.23)18.2507
2000's14 (21.54)29.6817
2010's30 (46.15)24.3611
2020's13 (20.00)2.80

Authors

AuthorsStudies
Du, J; Guo, L; Li, W; Li, Y; Qiu, J; Wang, L; Zhang, T1
Mohajeri, D; Nourazar, MA; Sokouti, H1
Dolrahman, N; Mukkhaphrom, W; Sutirek, J; Thong-Asa, W1
Albalawi, MA; Alzlaiq, WA; Atif, HM; Bilasy, SE; Eladl, MA; Elaidy, SM; ElSayed, MH; Farag, NE; Helal, MA; Helaly, AMN; Hisham, FA; Ibrahiem, AT; Khella, HWZ; Osman, NMS; Zaitone, SA1
Bilal, B; Erbas, O; Erdogan, MA; Kirazlar, M; Yigitturk, G1
Fu, J; Gao, X; Liu, S; Lu, F; Lu, Y; Mohammed, SAD; Nan, Y; Wang, T; Wang, Y1
Deng, Y; Ke, M; Wu, H; Xie, B1
Abolhassani, M; Juybari, KB; Mehrabani, M; Mirzamohammadi, S; Nematollahi, MH; Paseban, H; Saravani, M; Sharifi, AM; Tarzi, ME1
Araujo, SM; Bortolotto, VC; Dahleh, MMM; de Freitas Couto, S; Jardim, EF; Meichtry, LB; Musachio, EAS; Petri Guerra, G; Poetini, MR; Prigol, M; Ramborger, BP; Roehrs, R1
Jiang, X; Qiao, B; Yue, Y1
Liu, L; Wang, H; Wang, J1
Ishiguro, T; Itoh, T; Kaba, N; Tsuda, S; Umemoto, H; Yasugi, S; Yoda, M1
Ahmad, B; Bibi, S; Chauhdary, Z; Raza, Z; Saleem, U; Shah, MA; Shah, S; Shehzad, A1
Gao, Z; Liu, Y; Shen, L; Wang, Z1
Ju, B; Li, JF; Liu, YJ; Wang, HT; Wang, SS; Wang, YL; Yang, XP; Yin, HL; Zeng, ZL; Zhang, YZ1
Drakulić, D; Ilić, TV; Miletić, J; Miljković, M; Pejić, S; Petković, M; Prostran, M; Stefanović, A; Stojanov, M1
Dai, L; Kuang, S; Li, J; Rao, Z; Tang, X; Yang, L; Zhong, H; Zhong, Z1
Babayan-Tazehkand, A; Dargahi, T; Haghdoost-Yazdi, H; Rastgoo, N; Sarbazi Golezari, A; Sarukhani, M1
Gong, J; Li, X; Liu, YY; Xia, XJ; Yang, QS; Zhang, L; Zhang, Q1
Carro, E; De la Fuente, M; Garrido, A; Kobayashi, H; Martínez de Toda, I; Molina, JA; Vida, C1
Ansari, SA; Azimullah, S; Javed, H; Meeran, MFN; Ojha, S1
Adem, A; Azimullah, S; Beiram, R; Jalal, FY; Jayaraj, RL; Meeran, MFN; Ojha, SK1
Bhattacharya, R; Kaushal, M; Lomash, V; Satpute, R1
Ciobica, A; Hritcu, L1
Ding, QF; Liu, CB; Lu, FB; Pan, HB; Wang, R1
Bao, Q; Feng, G; Jiang, J; Li, S; Zhang, Z; Zhou, L1
Borgohain, R; Devi, YP; Kumudini, N; Kutala, VK; Mridula, R; Naushad, SM; Uma, A1
Li, J; Li, X; Wang, LN; Xiao, HL; Yang, JJ1
An, D; Li, SL; Peng, Y; Sun, YP; Wang, DM; Xu, H; Yin, SM; Yu, DQ; Zhang, WQ; Zhao, D; Zhao, J1
Cruickshank, TM; Reyes, AR; Ziman, MR1
Hu, R; Li, K; Li, X; Lu, C; Wang, Y; Wei, Y1
Chen, C; Fan, Q; Huang, J; Pan, X; Wei, H1
Baluchnejadmojarad, T; Kiasalari, Z; Roghani, M1
Cui, Q; Li, X; Zhu, H1
Qi, Z; Tong, Q; Yuan, Y; Zhang, K; Zhou, H1
Dolatshahi, M; Farbood, Y; Khodadadi, A; Mansouri, SM; Sarkaki, A1
Ataç Uçar, C; Aytaç, B; Çubukçu, HC; Durak, İ; Durak, ZE; Gökçe Çokal, B; Güneş, HN; Keskin Güler, S; Yoldaş, TK; Yurtdaş, M1
Baluchnejadmojarad, T; Rabiee, N; Roghani, M; Zabihnejad, S1
Bloomer, RJ; Callegari, J; Karlage, RE; Ledoux, MS; Pfeiffer, RF; Schilling, BK1
Chen, P; Chen, Z; Li, A; Liang, LP; Lou, XC; Wang, SL; Wu, XK; Zhao, CJ1
Alam, MM; Anwer, T; Azam, F; Barodia, SK1
Chen, CM; Chen, YC; Cheng, HS; Cheng, ML; Chiu, DT; Liu, JL; Wu, YR1
Ahmed, MA; Alkskas, IA; Azam, F1
Beal, MF; Calingasan, NY; Cormier, K; Ferrante, RJ; Smith, K; Wille, EJ; Yang, L1
Hirai, K; Ono, S; Tokuda, E1
Bach, JH; Bing, G; Jin, CH; Jung, BD; Kim, HC; Nah, SY; Nguyen, XK; Park, SJ; Shin, EJ; Wie, MB1
Ferrer, I; Gomez, A1
Kuo, WW; Liu, WH; Tsai, SJ; Yin, MC1
An, L; Dong, W; Dong, Y; Liu, S; Tang, B1
Li, S; Pu, XP1
Ayala, V; Dalfó, E; Ferrer, I; Martínez, A; Pamplona, R; Portero-Otín, M1
Moreira, PI; Perry, G; Sayre, LM; Smith, MA1
Barthwal, MK; Dikshit, M; Rajani, M; Shukla, R; Srivastava, N1
Gill, KD; Kaur, P; Kumar, B; Prabhakar, S; Sharma, A1
Hou, CY; Kou, ST; Pu, ZH; Tian, YP; Xie, XX1
Kerk, S; Meng Lim, T; Zhou, Z1
Deng, YL; Liu, XQ; Qing, H; Wang, R; Zheng, XL1
Cooper, JM; Harley, A; Schapira, AH1
Ahlskog, JE; Kokmen, E; Low, PA; Nickander, KK; Petersen, RC; Tyce, GM; Uitti, RJ1
Ahlskog, JE; Low, PA; Nickander, KK; O'Brien, JF; Tyce, GM; Uitti, RJ1
Arencibia, R; Broche, F; Castellano, O; Céspedes, EM; García, JC; Gómez, AA; González-Fraguela, ME1
Chaudhary, AK; Kalra, J; Mantha, SV; Prasad, K; Rajput, AH1
Codoceo, R; Fernandez-Calle, P; Jiménez-Jiménez, FJ; Lalinde, L; Molina, JA; Pondal, M; Tenias, JM; Vazquez, A1
Agid, F; Agid, Y; Carter, C; Dexter, D; Jenner, P; Lees, AJ; Marsden, CD1
Agid, Y; Carter, CJ; Dexter, DT; Javoy-Agid, F; Jenner, P; Lees, A; Marsden, CD; Wells, FR1

Reviews

2 review(s) available for malondialdehyde and Parkinson Disease

ArticleYear
A systematic review and meta-analysis of strength training in individuals with multiple sclerosis or Parkinson disease.
    Medicine, 2015, Volume: 94, Issue:4

    Topics: Biomarkers; Disease Progression; Electromyography; Fatigue; Glutathione Peroxidase; Humans; Hydrogen Peroxide; Malondialdehyde; Mobility Limitation; Multiple Sclerosis; Muscle Strength; Parkinson Disease; Postural Balance; Quality of Life; Resistance Training; Superoxide Dismutase

2015
Metal ions and oxidative protein modification in neurological disease.
    Annali dell'Istituto superiore di sanita, 2005, Volume: 41, Issue:2

    Topics: Aldehydes; alpha-Synuclein; Alzheimer Disease; Animals; Cross-Linking Reagents; Encephalomyelitis, Autoimmune, Experimental; Free Radicals; Glycation End Products, Advanced; Humans; Lipid Peroxidation; Malondialdehyde; Metals; Mice; Multiple Sclerosis; Neurodegenerative Diseases; Oxidation-Reduction; Oxidative Stress; Parkinson Disease; Proteins; Rats; Reactive Oxygen Species

2005

Trials

2 trial(s) available for malondialdehyde and Parkinson Disease

ArticleYear
Effect of resistance training on blood oxidative stress in Parkinson disease.
    Medicine and science in sports and exercise, 2008, Volume: 40, Issue:8

    Topics: Biomarkers; Female; Humans; Hydrogen Peroxide; Male; Malondialdehyde; Middle Aged; Oxidative Stress; Parkinson Disease; Resistance Training

2008
[Indicators of oxidative stress and the effect of antioxidant treatment in patients with primary Parkinson disease].
    Revista de neurologia, 1998, Volume: 26, Issue:149

    Topics: Antioxidants; Ascorbic Acid; Biomarkers; Catalase; Disease Progression; Humans; Malondialdehyde; Monoamine Oxidase Inhibitors; Oxidative Stress; Parkinson Disease; Phospholipases A; Phospholipases A2; Reactive Oxygen Species; Spectrophotometry; Vitamin E

1998

Other Studies

61 other study(ies) available for malondialdehyde and Parkinson Disease

ArticleYear
Shikonin ameliorates oxidative stress and neuroinflammation via the Akt/ERK/JNK/NF-κB signalling pathways in a model of Parkinson's disease.
    Clinical and experimental pharmacology & physiology, 2022, Volume: 49, Issue:11

    Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Cyclooxygenase 2; Disease Models, Animal; Dopamine Plasma Membrane Transport Proteins; Glutathione; Interleukin-6; JNK Mitogen-Activated Protein Kinases; Malondialdehyde; Mice; Mice, Inbred C57BL; Naphthoquinones; Neuroinflammatory Diseases; Neurotoxins; NF-kappa B; Nitric Oxide Synthase Type II; Oxidative Stress; Parkinson Disease; Proto-Oncogene Proteins c-akt; Superoxide Dismutase; Tumor Necrosis Factor-alpha; Tyrosine 3-Monooxygenase

2022
6-Hydroxydopamine-Induced Neurotoxicity in Rat Model of Parkinson's Disease: Is Reversed via Anti-Oxidative Activities of Curcumin and Aerobic Exercise Therapy.
    Physiological research, 2022, Aug-31, Volume: 71, Issue:4

    Topics: alpha-Synuclein; Animals; Antioxidants; Apomorphine; Curcumin; Disease Models, Animal; Glutathione Peroxidase; Malondialdehyde; Neuroprotective Agents; Neurotoxicity Syndromes; Neurotoxins; Oxidopamine; Parkinson Disease; Rats; Substantia Nigra

2022
Benefits of p-coumaric acid in mice with rotenone-induced neurodegeneration.
    Metabolic brain disease, 2023, Volume: 38, Issue:1

    Topics: Animals; Disease Models, Animal; Dopaminergic Neurons; Male; Malondialdehyde; Mice; Neurodegenerative Diseases; Neuroprotective Agents; Oxidative Stress; Parkinson Disease; Rotenone; Tumor Necrosis Factor-alpha

2023
Betanin improves motor function and alleviates experimental Parkinsonism via downregulation of TLR4/MyD88/NF-κB pathway: Molecular docking and biological investigations.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2023, Volume: 164

    Topics: Animals; Betacyanins; Down-Regulation; Male; Malondialdehyde; Mice; Molecular Docking Simulation; Myeloid Differentiation Factor 88; NF-kappa B; Parkinson Disease; Parkinsonian Disorders; Rotenone; Toll-Like Receptor 4

2023
Lacosamide exhibits neuroprotective effects in a rat model of Parkinson's disease.
    Journal of chemical neuroanatomy, 2023, Volume: 132

    Topics: Animals; Apomorphine; Disease Models, Animal; Dopamine; Dopaminergic Neurons; Lacosamide; Male; Malondialdehyde; Mice; Neuroprotective Agents; Parkinson Disease; Rats; Rats, Sprague-Dawley; Rotenone; Substantia Nigra; Tumor Necrosis Factor-alpha

2023
Efficacy and mechanism study of Baichanting compound, a combination of Acanthopanax senticosus (Rupr. and Maxim.) Harms, Paeonia lactiflora Pall and Uncaria rhynchophylla (Miq.) Miq. ex Havil, on Parkinson's disease based on metagenomics and metabolomics.
    Journal of ethnopharmacology, 2024, Jan-30, Volume: 319, Issue:Pt 1

    Topics: Animals; Antioxidants; Chromatography, Liquid; Dopamine; Eleutherococcus; Glutamic Acid; Glutamine; Interleukin-6; Malondialdehyde; Metabolomics; Mice; Mice, Inbred C57BL; Paeonia; Parkinson Disease; Superoxide Dismutase; Tandem Mass Spectrometry; Tumor Necrosis Factor-alpha

2024
High-fat diet causes increased endogenous neurotoxins and phenotype of Parkinson's disease in mice.
    Acta biochimica et biophysica Sinica, 2019, Sep-06, Volume: 51, Issue:9

    Topics: Animals; Diabetes Mellitus, Type 2; Diet, High-Fat; Glucose Intolerance; Isoquinolines; Malondialdehyde; Mice; Neurotoxins; Parkinson Disease; Salsoline Alkaloids

2019
Protective effect of hydralazine on a cellular model of Parkinson's disease: a possible role of hypoxia-inducible factor (HIF)-1α.
    Biochemistry and cell biology = Biochimie et biologie cellulaire, 2020, Volume: 98, Issue:3

    Topics: Antioxidants; Apoptosis; Cell Hypoxia; Cell Line, Tumor; Cell Survival; Dopamine; Humans; Hydralazine; Hypoxia-Inducible Factor 1, alpha Subunit; Malondialdehyde; Nitric Oxide; Oxidopamine; Parkinson Disease; Superoxide Dismutase

2020
Bisphenol A exposure is involved in the development of Parkinson like disease in Drosophila melanogaster.
    Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 2020, Volume: 137

    Topics: Animals; Benzhydryl Compounds; Catalase; Disease Models, Animal; Dopamine; Drosophila melanogaster; Drosophila Proteins; Female; Glutathione Transferase; Humans; Male; Malondialdehyde; Mitochondria; No-Observed-Adverse-Effect Level; Oxidative Stress; Parkinson Disease; Phenols; Reactive Oxygen Species; Superoxide Dismutase

2020
Tormentic acid confers protection against oxidative stress injury in rats with Parkinson's disease by targeting the Wnt/β-catenin signaling pathway.
    Cellular and molecular biology (Noisy-le-Grand, France), 2020, Apr-20, Volume: 66, Issue:1

    Topics: Animals; Behavior, Animal; Cell Survival; Female; Glutathione Peroxidase; Male; Malondialdehyde; Memory; Neuroprotective Agents; Oxidative Stress; Oxidopamine; Parkinson Disease; PC12 Cells; Rats; Rats, Wistar; RNA, Messenger; Superoxide Dismutase; Triterpenes; Wnt Signaling Pathway

2020
Hydrogen sulfide alleviates oxidative stress injury and reduces apoptosis induced by MPP
    Molecular and cellular biochemistry, 2020, Volume: 472, Issue:1-2

    Topics: 1-Methyl-4-phenylpyridinium; Apoptosis; Caspase 3; Cell Survival; Gasotransmitters; Herbicides; Humans; Hydrogen Sulfide; Malondialdehyde; Neuroblastoma; Nitric Oxide Synthase Type II; Oxidative Stress; Parkinson Disease; Proto-Oncogene Proteins c-bcl-2; Reactive Oxygen Species; Signal Transduction; Superoxide Dismutase; Tumor Cells, Cultured

2020
Protective Effect of Nervonic Acid Against 6-Hydroxydopamine-Induced Oxidative Stress in PC-12 Cells.
    Journal of oleo science, 2021, Volume: 70, Issue:1

    Topics: Animals; Antioxidants; Brain; Cell Membrane; Cell Survival; Fatty Acids, Monounsaturated; Glutamate-Cysteine Ligase; Glutathione; Lipid Bilayers; Lipid Peroxidation; Malondialdehyde; Neuroprotective Agents; Oxidative Stress; Oxidopamine; Parkinson Disease; PC12 Cells; Rats; Superoxide Dismutase

2021
Antiparkinsonian activity of Cucurbita pepo seeds along with possible underlying mechanism.
    Metabolic brain disease, 2021, Volume: 36, Issue:6

    Topics: Animals; Antioxidants; Antiparkinson Agents; Cucurbita; Malondialdehyde; Parkinson Disease; Plant Extracts; Rats; Superoxide Dismutase

2021
The Relationship between Levels of Serum Metal Ions and Parkinson's Disease.
    Clinical laboratory, 2021, May-01, Volume: 67, Issue:5

    Topics: Humans; Ions; Malondialdehyde; Parkinson Disease; Substantia Nigra; Superoxide Dismutase

2021
Protective Effect of Curcumin Against Oxidative Stress-Induced Injury in Rats with Parkinson's Disease Through the Wnt/ β-Catenin Signaling Pathway.
    Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, 2017, Volume: 43, Issue:6

    Topics: Animals; Apoptosis; Astrocytes; Behavior, Animal; beta Catenin; Cell Adhesion; Cells, Cultured; Curcumin; Cyclin D1; Disease Models, Animal; Dopamine Plasma Membrane Transport Proteins; Glial Fibrillary Acidic Protein; Glutathione Peroxidase; Immunohistochemistry; Intercellular Signaling Peptides and Proteins; Male; Malondialdehyde; Membrane Potential, Mitochondrial; Oxidative Stress; Oxidopamine; Parkinson Disease; Protective Agents; Proto-Oncogene Proteins c-myc; Rats; Rats, Sprague-Dawley; Superoxide Dismutase; Tyrosine 3-Monooxygenase; Wnt Signaling Pathway; Wnt3 Protein

2017
Prooxidant-antioxidant balance, advanced oxidation protein products and lipid peroxidation in Serbian patients with Parkinson's disease.
    The International journal of neuroscience, 2018, Volume: 128, Issue:7

    Topics: Adult; Advanced Oxidation Protein Products; Aged; Aged, 80 and over; Aldehydes; Antioxidants; Female; Humans; Lipid Peroxidation; Male; Malondialdehyde; Middle Aged; Oxidants; Parkinson Disease; Serbia; Severity of Illness Index; Statistics, Nonparametric

2018
Effects of Ginkgo Biloba Extract on A53T α-Synuclein Transgenic Mouse Models of Parkinson's Disease.
    The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques, 2018, Volume: 45, Issue:2

    Topics: Alanine; alpha-Synuclein; Animals; Antiparkinson Agents; Disease Models, Animal; Dopamine Plasma Membrane Transport Proteins; Dose-Response Relationship, Drug; Ginkgo biloba; Glutathione; Glutathione Peroxidase; Locomotion; Malondialdehyde; Mice; Mice, Transgenic; Muscle Strength; Mutation; Parkinson Disease; Plant Extracts; Superoxide Dismutase; Swimming; Threonine

2018
Evaluation of the antiparkinsonism and neuroprotective effects of hydrogen sulfide in acute 6-hydroxydopamine-induced animal model of Parkinson's disease: behavioral, histological and biochemical studies.
    Neurological research, 2018, Volume: 40, Issue:7

    Topics: Analysis of Variance; Animals; Apomorphine; Corpus Striatum; Disease Models, Animal; Dopamine; Dopamine Agonists; Dose-Response Relationship, Drug; Glutathione Peroxidase; Hydrogen Sulfide; Male; Malondialdehyde; Motor Activity; Neuroprotective Agents; Oxidopamine; Parkinson Disease; Postural Balance; Rats; Rats, Wistar; Rotarod Performance Test; Superoxide Dismutase; Sympatholytics

2018
Lentiviral Vector-Mediated SHC3 Silencing Exacerbates Oxidative Stress Injury in Nigral Dopamine Neurons by Regulating the PI3K-AKT-FoxO Signaling Pathway in Rats with Parkinson's Disease.
    Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, 2018, Volume: 49, Issue:3

    Topics: Animals; Behavior, Animal; Disease Models, Animal; Dopaminergic Neurons; Forkhead Transcription Factors; Lentivirus; Male; Malondialdehyde; Oxidative Stress; Parkinson Disease; PC12 Cells; Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins c-akt; Rats; Rats, Sprague-Dawley; RNA Interference; RNA, Small Interfering; Signal Transduction; Src Homology 2 Domain-Containing, Transforming Protein 3; Superoxide Dismutase

2018
Lymphoproliferation Impairment and Oxidative Stress in Blood Cells from Early Parkinson's Disease Patients.
    International journal of molecular sciences, 2019, Feb-12, Volume: 20, Issue:3

    Topics: Adult; Aged; Biomarkers; Blood Cells; Cell Proliferation; Cross-Sectional Studies; Female; Glutathione; Glutathione Peroxidase; Humans; Lymphocytes; Male; Malondialdehyde; Neutrophils; Oxidation-Reduction; Oxidative Stress; Parkinson Disease

2019
Neuroprotective Effects of Thymol, a Dietary Monoterpene Against Dopaminergic Neurodegeneration in Rotenone-Induced Rat Model of Parkinson's Disease.
    International journal of molecular sciences, 2019, Mar-27, Volume: 20, Issue:7

    Topics: Animals; Catalase; Cyclooxygenase 2; Cytokines; Diet; Disease Models, Animal; Dopaminergic Neurons; Glutathione; Inflammation Mediators; Lipid Peroxidation; Male; Malondialdehyde; Neostriatum; Nerve Degeneration; Neuroglia; Neuroprotective Agents; Nitric Oxide Synthase Type II; Parkinson Disease; Rats, Wistar; Rotenone; Substantia Nigra; Superoxide Dismutase; Thymol; Tyrosine 3-Monooxygenase

2019
Lycopodium Attenuates Loss of Dopaminergic Neurons by Suppressing Oxidative Stress and Neuroinflammation in a Rat Model of Parkinson's Disease.
    Molecules (Basel, Switzerland), 2019, Jun-10, Volume: 24, Issue:11

    Topics: alpha-Synuclein; Animals; Antioxidants; Brain; Catalase; Cyclooxygenase 2; Cytokines; Disease Models, Animal; Dopaminergic Neurons; Glutathione; Inflammation; Inflammation Mediators; Lipid Peroxidation; Lycopodium; Male; Malondialdehyde; Matrix Metalloproteinases; Microglia; Nerve Degeneration; Neuroprotection; Nitric Oxide; Nitric Oxide Synthase Type II; Nitrites; Oxidative Stress; Parkinson Disease; Plant Extracts; Rats, Wistar; Rotenone; Superoxide Dismutase

2019
Neuroprotective effects of α-ketoglutarate and ethyl pyruvate against motor dysfunction and oxidative changes caused by repeated 1-methyl-4-phenyl-1,2,3,6 tetrahydropyridine exposure in mice.
    Human & experimental toxicology, 2013, Volume: 32, Issue:7

    Topics: Animals; Antioxidants; Electron Transport Complex I; Glutathione; Ketoglutaric Acids; Male; Malondialdehyde; Mice; MPTP Poisoning; Neuroprotective Agents; Oxidative Stress; Parkinson Disease; Peroxidase; Psychomotor Performance; Pyruvates; Superoxide Dismutase

2013
Intranigral lipopolysaccharide administration induced behavioral deficits and oxidative stress damage in laboratory rats: relevance for Parkinson's disease.
    Behavioural brain research, 2013, Sep-15, Volume: 253

    Topics: Animals; Behavior, Animal; Glutathione Peroxidase; Hippocampus; Lipid Peroxidation; Lipopolysaccharides; Male; Malondialdehyde; Maze Learning; Memory; Microinjections; Neuroprotective Agents; Oxidative Stress; Parkinson Disease; Pergolide; Rats; Rats, Wistar; Rotation; Substantia Nigra; Superoxide Dismutase; Temporal Lobe

2013
[Effect of lycopene on oxidative stress and behavioral deficits in rotenone induced model of Parkinson's disease].
    Zhongguo ying yong sheng li xue za zhi = Zhongguo yingyong shenglixue zazhi = Chinese journal of applied physiology, 2013, Volume: 29, Issue:4

    Topics: Animals; Behavior, Animal; Brain; Carotenoids; Disease Models, Animal; Dopamine; Lycopene; Male; Malondialdehyde; Mice; Mice, Inbred C57BL; Neurons; Oxidative Stress; Parkinson Disease; Rotenone; Superoxide Dismutase

2013
Protective effect of chinonin in MPTP-induced C57BL/6 mouse model of Parkinson's disease.
    Biological & pharmaceutical bulletin, 2014, Volume: 37, Issue:8

    Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 3,4-Dihydroxyphenylacetic Acid; Animals; Corpus Striatum; Disease Models, Animal; Dopamine; Gait; Glutathione; Homovanillic Acid; Male; Malondialdehyde; Mice, Inbred C57BL; Neurons; Neuroprotective Agents; Neurotoxins; Parkinson Disease; Substantia Nigra; Superoxide Dismutase; Xanthones

2014
Association of Parkinson's disease with altered serum levels of lead and transition metals among South Indian subjects.
    Indian journal of biochemistry & biophysics, 2014, Volume: 51, Issue:2

    Topics: Case-Control Studies; Copper; Female; Humans; India; Iron; Lead; Male; Malondialdehyde; Manganese; Mass Spectrometry; Middle Aged; Oxidative Stress; Parkinson Disease; Transition Elements

2014
[Effect of electroacupuncture intervention on levels of SOD, GSH, GSH-Px, MDA, and apoptosis of dopaminergic neurons in substantia Nigra in rats with Parkinson's disease].
    Zhen ci yan jiu = Acupuncture research, 2014, Volume: 39, Issue:3

    Topics: Animals; Apoptosis; Dopaminergic Neurons; Electroacupuncture; Glutathione; Glutathione Peroxidase; Humans; Male; Malondialdehyde; Oxidative Stress; Parkinson Disease; Rats; Substantia Nigra; Superoxides

2014
Neuroprotection by scorpion venom heat resistant peptide in 6-hydroxydopamine rat model of early-stage Parkinson's disease.
    Sheng li xue bao : [Acta physiologica Sinica], 2014, Dec-25, Volume: 66, Issue:6

    Topics: Animals; Antioxidants; Corpus Striatum; Disease Models, Animal; Dopaminergic Neurons; Malondialdehyde; Mesencephalon; Mitochondria; Neuroprotective Agents; Oxidative Stress; Oxidopamine; Parkinson Disease; Peptides; Rats; Rats, Sprague-Dawley; Scorpion Venoms; Superoxide Dismutase

2014
Transcranial Direct Current Stimulation Ameliorates Behavioral Deficits and Reduces Oxidative Stress in 1-Methyl-4-Phenyl-1,2,3,6-Tetrahydropyridine-Induced Mouse Model of Parkinson's Disease.
    Neuromodulation : journal of the International Neuromodulation Society, 2015, Volume: 18, Issue:6

    Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Brain; Disease Models, Animal; Dopamine; Glutathione Peroxidase; Male; Malondialdehyde; Mental Disorders; Mice; Mice, Inbred C57BL; Oxidative Stress; Parkinson Disease; Psychomotor Performance; Superoxide Dismutase; Transcranial Direct Current Stimulation; Tyrosine 3-Monooxygenase

2015
Neuroprotective effect of combined therapy with hyperbaric oxygen and madopar on 6-hydroxydopamine-induced Parkinson's disease in rats.
    Neuroscience letters, 2015, Jul-23, Volume: 600

    Topics: Animals; Apomorphine; Benserazide; Combined Modality Therapy; Drug Combinations; Glial Fibrillary Acidic Protein; Glutathione Peroxidase; Hyperbaric Oxygenation; Levodopa; Lipid Peroxidation; Male; Malondialdehyde; Nerve Degeneration; Neuroprotective Agents; Oxidative Stress; Oxidopamine; Parkinson Disease; Proto-Oncogene Proteins c-bcl-2; Rats, Wistar; Stereotyped Behavior; Substantia Nigra; Superoxide Dismutase; Tyrosine 3-Monooxygenase

2015
Hypericum Perforatum Hydroalcoholic Extract Mitigates Motor Dysfunction and is Neuroprotective in Intrastriatal 6-Hydroxydopamine Rat Model of Parkinson's Disease.
    Cellular and molecular neurobiology, 2016, Volume: 36, Issue:4

    Topics: Animals; Apomorphine; Catalase; Corpus Striatum; Disease Models, Animal; Ethanol; Glutathione; Hypericum; Male; Malondialdehyde; Mitogen-Activated Protein Kinases; Motor Activity; Neuroprotective Agents; Oxidopamine; Parkinson Disease; Plant Extracts; Rats, Wistar; Reaction Time; Tumor Necrosis Factor-alpha; Tyrosine 3-Monooxygenase; Water

2016
Curcumin ameliorates dopaminergic neuronal oxidative damage via activation of the Akt/Nrf2 pathway.
    Molecular medicine reports, 2016, Volume: 13, Issue:2

    Topics: Animals; Antioxidants; Chromones; Curcumin; Dopaminergic Neurons; Glutathione; HEK293 Cells; Humans; Male; Malondialdehyde; Morpholines; Neuroprotection; Neuroprotective Agents; NF-E2-Related Factor 2; Oxidative Stress; Parkinson Disease; Proto-Oncogene Proteins c-akt; Rats, Inbred Lew; Reactive Oxygen Species; RNA, Small Interfering; Rotenone

2016
[Study on changes of plasma levels of oxidative stress biomarkers and its relation with cognition function in patients with parkinson's disease].
    Zhonghua yi xue za zhi, 2015, Nov-03, Volume: 95, Issue:41

    Topics: Antioxidants; Biomarkers; Catalase; Cognition; Cognition Disorders; Female; Glutathione; Glutathione Peroxidase; Humans; Male; Malondialdehyde; Oxidative Stress; Parkinson Disease; Superoxide Dismutase

2015
Neuroprotective Effects of Ellagic Acid in a Rat Model of Parkinson's Disease.
    Acta medica Iranica, 2016, Volume: 54, Issue:8

    Topics: Animals; Antioxidants; Brain; Corpus Striatum; Ellagic Acid; Glutathione Peroxidase; Male; Malondialdehyde; Medial Forebrain Bundle; Models, Animal; Neuroprotective Agents; Oxidopamine; Parkinson Disease; Rats; Rats, Wistar

2016
Serum glutathione peroxidase, xanthine oxidase, and superoxide dismutase activities and malondialdehyde levels in patients with Parkinson's disease.
    Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology, 2017, Volume: 38, Issue:3

    Topics: Aged; Antioxidants; Female; Glutathione Peroxidase; Humans; Male; Malondialdehyde; Middle Aged; Oxidants; Oxidation-Reduction; Oxidative Stress; Parkinson Disease; Superoxide Dismutase; Xanthine Oxidase

2017
Ellagic acid exerts protective effect in intrastriatal 6-hydroxydopamine rat model of Parkinson's disease: Possible involvement of ERβ/Nrf2/HO-1 signaling.
    Brain research, 2017, 05-01, Volume: 1662

    Topics: Animals; Antioxidants; Apoptosis; Corpus Striatum; Dopaminergic Neurons; Ellagic Acid; Estrogen Receptor beta; Heme Oxygenase (Decyclizing); Malondialdehyde; Models, Animal; Monoamine Oxidase; Neostriatum; Neuroprotective Agents; NF-E2-Related Factor 2; Oxidative Stress; Oxidopamine; Parkinson Disease; Pars Compacta; Rats; Reactive Oxygen Species; Signal Transduction; Substantia Nigra

2017
Catalytic metalloporphyrin protects against paraquat neurotoxicity in vivo.
    Biomedical and environmental sciences : BES, 2008, Volume: 21, Issue:3

    Topics: Animals; Antioxidants; Antiparkinson Agents; Behavior, Animal; Catalysis; Corpus Striatum; Dopamine; Male; Malondialdehyde; Metalloporphyrins; Mice; Mice, Inbred C57BL; Neuroprotective Agents; Paraquat; Parkinson Disease; Substantia Nigra; Tyrosine 3-Monooxygenase

2008
Neuroprotective effect of naphtha[1,2-d]thiazol-2-amine in an animal model of Parkinson's disease.
    Journal of enzyme inhibition and medicinal chemistry, 2009, Volume: 24, Issue:3

    Topics: Animals; Antioxidants; Brain; Catalepsy; Disease Models, Animal; Dose-Response Relationship, Drug; Glutathione; Glutathione Peroxidase; Haloperidol; Male; Malondialdehyde; Mice; Naphthalenes; Neuroprotective Agents; Oxidative Stress; Parkinson Disease; Superoxide Dismutase; Thiazoles

2009
Increased oxidative damage in peripheral blood correlates with severity of Parkinson's disease.
    Neurobiology of disease, 2009, Volume: 33, Issue:3

    Topics: 8-Hydroxy-2'-Deoxyguanosine; Aged; Analysis of Variance; Blood Chemical Analysis; Chromatography, High Pressure Liquid; Deoxyguanosine; Erythrocytes; Female; Glutathione Peroxidase; Humans; Leukocytes; Logistic Models; Male; Malondialdehyde; Oxidative Stress; Parkinson Disease; Risk Factors; Vitamin E

2009
Synthesis of some urea and thiourea derivatives of 3-phenyl/ethyl-2-thioxo-2,3-dihydrothiazolo[4,5-d]pyrimidine and their antagonistic effects on haloperidol-induced catalepsy and oxidative stress in mice.
    European journal of medicinal chemistry, 2009, Volume: 44, Issue:10

    Topics: Animals; Anti-Dyskinesia Agents; Antiparkinson Agents; Brain; Catalepsy; Glutathione; Glutathione Peroxidase; Haloperidol; Male; Malondialdehyde; Mice; Oxidative Stress; Parkinson Disease; Pyrimidines; Superoxide Dismutase; Thiourea; Urea

2009
Combination therapy with coenzyme Q10 and creatine produces additive neuroprotective effects in models of Parkinson's and Huntington's diseases.
    Journal of neurochemistry, 2009, Volume: 109, Issue:5

    Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 8-Hydroxy-2'-Deoxyguanosine; alpha-Synuclein; Analysis of Variance; Animals; Chromatography, High Pressure Liquid; Creatine; Deoxyguanosine; Disease Models, Animal; Dopamine; Drug Therapy, Combination; Glutathione; Glutathione Disulfide; Huntington Disease; Lipid Peroxidation; Male; Malondialdehyde; Mice; Mice, Inbred C57BL; Neuroprotective Agents; Nitro Compounds; Parkinson Disease; Propionates; Rats; Rats, Inbred Lew; Tyrosine 3-Monooxygenase; Ubiquinone

2009
Effects of pergolide mesilate on metallothionein mRNAs expression in a mouse model for Parkinson disease.
    Biological & pharmaceutical bulletin, 2009, Volume: 32, Issue:10

    Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Antioxidants; Brain; Disease Models, Animal; Dopamine Agonists; Gene Expression; Lipid Peroxidation; Malondialdehyde; Metallothionein; Mice; Mice, Inbred C57BL; Parkinson Disease; Pergolide; RNA, Messenger

2009
Potentiation of methamphetamine neurotoxicity by intrastriatal lipopolysaccharide administration.
    Neurochemistry international, 2010, Volume: 56, Issue:2

    Topics: Aldehydes; Animals; Blotting, Western; Chromatography, High Pressure Liquid; Corpus Striatum; Drug Synergism; Lipopolysaccharides; Male; Malondialdehyde; Methamphetamine; Mice; Mice, Inbred C57BL; Motor Activity; Parkinson Disease

2010
Involvement of the cerebral cortex in Parkinson disease linked with G2019S LRRK2 mutation without cognitive impairment.
    Acta neuropathologica, 2010, Volume: 120, Issue:2

    Topics: Aged; Aged, 80 and over; alpha-Synuclein; Cerebral Cortex; Cognition Disorders; Electrophoresis, Gel, Two-Dimensional; Female; Glial Fibrillary Acidic Protein; Glycine; Humans; Leucine-Rich Repeat Serine-Threonine Protein Kinase-2; Malondialdehyde; Mass Spectrometry; Mutation; Parkinson Disease; Protein Serine-Threonine Kinases; Receptor for Advanced Glycation End Products; Receptors, Immunologic; Serine; Statistics, Nonparametric

2010
Antioxidative and anti-inflammatory protection from carnosine in the striatum of MPTP-treated mice.
    Journal of agricultural and food chemistry, 2010, Nov-10, Volume: 58, Issue:21

    Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Anti-Inflammatory Agents; Antioxidants; Carnosine; Corpus Striatum; Glutathione; Humans; Interleukin-6; Male; Malondialdehyde; Mice; Mice, Inbred C57BL; Neuroprotective Agents; Nitric Oxide Synthase Type II; Parkinson Disease; Tumor Necrosis Factor-alpha

2010
Protective effect of effective part of Acanthopanacis senticosus on damage of PC12 cells induced by MPP+.
    Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 2010, Volume: 35, Issue:15

    Topics: 1-Methyl-4-phenylpyridinium; Animals; Apoptosis; Araliaceae; Cell Survival; Disease Models, Animal; Drugs, Chinese Herbal; Humans; Malondialdehyde; Neurons; Neuroprotective Agents; Nitric Oxide; Parkinson Disease; PC12 Cells; Rats

2010
Neuroprotective effect of kaempferol against a 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced mouse model of Parkinson's disease.
    Biological & pharmaceutical bulletin, 2011, Volume: 34, Issue:8

    Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Antioxidants; Ataxia; Corpus Striatum; Disease Models, Animal; Dopamine; Glutathione Peroxidase; Kaempferols; Male; Malondialdehyde; Mice; Mice, Inbred C57BL; MPTP Poisoning; Neurons; Neuroprotective Agents; Parkinson Disease; Phytotherapy; Plant Extracts; Superoxide Dismutase

2011
Evidence of oxidative stress in the neocortex in incidental Lewy body disease.
    Journal of neuropathology and experimental neurology, 2005, Volume: 64, Issue:9

    Topics: Aged; Aged, 80 and over; Aldehydes; alpha-Synuclein; Blotting, Western; Docosahexaenoic Acids; Electrophoresis, Gel, Two-Dimensional; Fatty Acids; Female; Glycation End Products, Advanced; Humans; Immunohistochemistry; Lewy Body Disease; Male; Malondialdehyde; Mass Spectrometry; Neocortex; Nerve Tissue Proteins; Oxidative Stress; Parkinson Disease; Receptor for Advanced Glycation End Products; Receptors, Immunologic; Synucleins

2005
Nitrite and malondialdehyde content in cerebrospinal fluid of patients with Parkinson's disease.
    The International journal of neuroscience, 2006, Volume: 116, Issue:12

    Topics: Female; Free Radicals; Humans; Lipid Peroxidation; Male; Malondialdehyde; Middle Aged; Nitrates; Nitric Oxide; Nitrites; Oxidative Stress; Parkinson Disease; Severity of Illness Index

2006
Plasma lipid peroxidation and antioxidant status of Parkinson's disease patients in the Indian population.
    Parkinsonism & related disorders, 2008, Volume: 14, Issue:1

    Topics: Antioxidants; Female; Glutathione; Glutathione Peroxidase; Glutathione Reductase; Humans; India; Lipid Peroxidation; Male; Malondialdehyde; Oxidative Stress; Parkinson Disease; Sulfhydryl Compounds; Superoxide Dismutase

2008
[Effects of scalp catgut embedding on SOD, NO, MDA in the rat with Parkinson's disease].
    Zhongguo zhen jiu = Chinese acupuncture & moxibustion, 2007, Volume: 27, Issue:10

    Topics: Acupuncture Therapy; Animals; Catgut; Female; Male; Malondialdehyde; Nitric Oxide; Parkinson Disease; Rats; Rats, Wistar; Scalp; Superoxide Dismutase

2007
Endogenous dopamine (DA) renders dopaminergic cells vulnerable to challenge of proteasome inhibitor MG132.
    Free radical research, 2008, Volume: 42, Issue:5

    Topics: alpha-Methyltyrosine; Animals; Cell Survival; Cysteine Proteinase Inhibitors; Dopamine; Leupeptins; Malondialdehyde; Mice; Neurodegenerative Diseases; Neurons; Parkinson Disease; PC12 Cells; Proteasome Endopeptidase Complex; Proteasome Inhibitors; Rats; Tetrazolium Salts; Thiazoles

2008
Iron contributes to the formation of catechol isoquinolines and oxidative toxicity induced by overdose dopamine in dopaminergic SH-SY5Y cells.
    Neuroscience bulletin, 2008, Volume: 24, Issue:3

    Topics: Apoptosis; Catechols; Cell Line, Tumor; Cell Survival; Dopamine; Dose-Response Relationship, Drug; Humans; Hydroxyl Radical; Iron; Iron Metabolism Disorders; Isoquinolines; Malondialdehyde; Models, Biological; Nerve Degeneration; Neurons; Neurotoxins; Oxidative Stress; Parkinson Disease; Salsoline Alkaloids; Up-Regulation

2008
Iron induced oxidative stress and mitochondrial dysfunction: relevance to Parkinson's disease.
    Brain research, 1993, Nov-12, Volume: 627, Issue:2

    Topics: Animals; Electron Transport; Glutathione; Iron; Malondialdehyde; Mitochondria; Oxidation-Reduction; Parkinson Disease; PC12 Cells; Substantia Nigra

1993
No evidence for systemic oxidant stress in Parkinson's or Alzheimer's disease.
    Movement disorders : official journal of the Movement Disorder Society, 1995, Volume: 10, Issue:5

    Topics: Aged; Alzheimer Disease; Antiparkinson Agents; Brain; Cabergoline; Carbidopa; Diabetes Mellitus; Ergolines; Female; Free Radicals; Humans; Levodopa; Lipid Peroxidation; Male; Malondialdehyde; Oxidative Stress; Parkinson Disease; Selegiline; Vitamin E

1995
Levodopa and deprenyl treatment effects on peripheral indices of oxidant stress in Parkinson's disease.
    Neurology, 1996, Volume: 46, Issue:3

    Topics: 3,4-Dihydroxyphenylacetic Acid; Adult; Aged; Aged, 80 and over; Cysteinyldopa; Humans; Levodopa; Malondialdehyde; Methoxyhydroxyphenylglycol; Middle Aged; Oxidative Stress; Parkinson Disease; Selegiline

1996
Oxygen free radical producing activity of polymorphonuclear leukocytes in patients with Parkinson's disease.
    Molecular and cellular biochemistry, 1992, Jun-26, Volume: 112, Issue:2

    Topics: Aged; Female; Free Radicals; Humans; Luminescent Measurements; Male; Malondialdehyde; Middle Aged; Neutrophils; Parkinson Disease; Superoxides

1992
Serum lipid peroxides in patients with Parkinson's disease.
    Neuroscience letters, 1992, Mar-02, Volume: 136, Issue:2

    Topics: Aged; Female; Humans; Lipid Peroxides; Male; Malondialdehyde; Parkinson Disease; Risk Factors

1992
Lipid peroxidation as cause of nigral cell death in Parkinson's disease.
    Lancet (London, England), 1986, Sep-13, Volume: 2, Issue:8507

    Topics: Aged; Brain Chemistry; Cell Survival; Fatty Acids, Unsaturated; Humans; Lipid Peroxides; Malondialdehyde; Middle Aged; Parkinson Disease; Substantia Nigra

1986
Basal lipid peroxidation in substantia nigra is increased in Parkinson's disease.
    Journal of neurochemistry, 1989, Volume: 52, Issue:2

    Topics: Aged; Animals; Ascorbic Acid; Brain; Fatty Acids, Unsaturated; Female; Ferrous Compounds; Free Radicals; Humans; Hydrogen Peroxide; Lipid Peroxidation; Male; Malondialdehyde; Parkinson Disease; Postmortem Changes; Rats; Rats, Inbred Strains; Substantia Nigra; Thiobarbiturates

1989