malondialdehyde has been researched along with Infarction, Middle Cerebral Artery in 120 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 38 (31.67) | 29.6817 |
| 2010's | 75 (62.50) | 24.3611 |
| 2020's | 7 (5.83) | 2.80 |
| Authors | Studies |
|---|---|
| Bao, Z; Chao, H; Chen, B; He, J; Hu, J; Ji, J; Li, C; Liu, N; Miao, Z; Sun, G; Xu, L; Ye, Y; You, Y; Zhao, L; Zhao, P | 1 |
| Huang, GJ; Jiao, JK; Li, QN; Liu, X; Lu, YH; Shang, JF; Wang, JY; Wen, YL; Yan, MX; Zhang, XL | 1 |
| Liang, C; Tan, L; Tan, R; Wang, Y; Wu, Y | 1 |
| Bigdeli, MR; Khoshnazar, M; Parvardeh, S; Pouriran, R | 1 |
| Bai, L; Chen, X; Du, Y; Liu, L; Wang, D; Wang, L | 1 |
| Abreu-González, P; Argueso, M; Cáceres, JJ; García-Marín, V; Jiménez, A; Lorente, L; Martín, MM; Ramos, L; Sabatel, R; Solé-Violán, J | 1 |
| Chen, J; Jiang, C; Lao, Y; Li, X; Liang, J; Liao, L; Shi, J; Wang, Y; Wen, J; Zhang, J; Zhou, S | 1 |
| Wei, W; Yue, Y; Zhang, Y; Zhao, H | 1 |
| Liang, YB; Liu, RR; Song, PP; Xu, JM; Zhang, YS; Zhu, PZ; Zhu, YH | 1 |
| Ashraf, GM; Barreto, GE; Chavda, V; Patel, SS; Rajput, R | 1 |
| Chen, M; Cheng, Y; Du, S; Fan, J; Ma, S; Qu, H; Shi, J; Sun, H; Yao, Q; Zhan, S; Zhang, M; Zhang, X | 1 |
| Ge, G; Kang, CS; Wang, JJ; Zhu, JD | 1 |
| Darabi, S; Mohammadi, MT | 1 |
| Chen, H; Hu, Y; Ji, Y; Sun, J; Sun, L; Wang, L; Xue, B; Xue, H; Yan, X; Zhang, J | 1 |
| Chai, LJ; Guo, H; Hu, LM; Wang, FJ; Wang, SX; Zhang, Y | 1 |
| Liu, ZG; Wang, SJ; Xiao, N; Yan, RY; Yao, GT | 1 |
| Jiang, HL; Qu, Y; Zhang, HL; Zhang, XP | 1 |
| Chen, NN; Fu, XJ; Liu, HF; Wang, JP; Yu, L; Zhang, M; Zhao, YZ | 1 |
| Dong, Q; Hu, W; Ji, M; Li, S | 1 |
| Gupta, S; Gupta, YK; Jagannathan, NR; Sharma, U; Upadhayay, D | 1 |
| Abreu-González, P; Argueso, M; Cáceres, JJ; García-Marín, V; Jiménez, A; Lorente, L; Martín, MM; Pérez-Cejas, A; Ramos, L; Solé-Violán, J | 1 |
| Abd-Elsalam, RM; Abdel-Rahman, RF; El-Marasy, SA | 1 |
| Chen, MH; Fang, W; Li, N; Qin, S; Qin, T; Xie, L; Yang, Y | 1 |
| Liang, T; Meng, X; Sun, G; Sun, X; Xie, W; Xu, Q; Xu, X | 1 |
| Jing, G; Jinmin, Z; Li, Z; Min, L; Xinyong, L; Yaqing, J; Yulei, J | 1 |
| Cao, J; Duan, H; Duan, J; Huang, Z; Wu, Q; Xu, S; Yang, Z; Zhang, S; Zhao, Y; Zhu, Z | 1 |
| Chen, X; He, Q; Kang, J; Liang, S; Luo, L; Qi, Y; Wang, S | 1 |
| Seetapun, S; Wang, Y; Yaoling, J; Zhu, YZ | 1 |
| Cao, Y; Liang, F; Ni, W; Wang, B; Wu, N; Xi, H; Xia, D; Zhang, S | 1 |
| Ates, N; Dillioglugil, MO; Ekici, F; Gurol, G; Karson, A; Kir, HM | 1 |
| Jittiwat, J; Kirisattayakul, W; Muchimapura, S; Tong-Un, T; Wannanon, P; Wattanathorn, J | 1 |
| Li, Q; Sun, X; Wang, J; Yang, GY; Zhai, Y; Zhang, T; Zhang, Z | 1 |
| Han, B; Jia, D; Yang, S; Zhao, J | 1 |
| Attari, F; Fanaei, H; Hassanzade, G; Javadimehr, M; Karimian, SM; Kasaeian, A; Khayat, S; Ramezani, V; Sadeghipour, HR | 1 |
| Gao, PJ; Lin, XJ; Shen, GX; Wang, RY; Yang, GY | 1 |
| Liu, PQ; Ma, RQ; Ma, YH | 1 |
| Deng, XL; Li, GR; Wang, Y; Yu, W; Zhao, LM; Zhou, DX | 1 |
| Chen, L; Fu, B; Wang, X; Zhang, J; Zhang, X; Zhao, T; Zhao, Y | 1 |
| Li, L; Liu, Y; Wu, J; Wu, X; Zhao, J; Zhao, Y; Zhu, K | 1 |
| Chen, M; Ding, Y; Li, Y; Wang, M; Wen, A | 1 |
| Barygin, OI; Isaeva, AV; Korzhevskii, DE; Morozov, VA; Portsel, MN; Tihonov, DB; Veselkina, OS; Vlasov, TD | 1 |
| Fang, Y; Feng, W; Qian, Z; Wang, Q; Xu, J; Yin, X; Zhao, L | 1 |
| Hang, X; Shang, A; Wang, H; Wang, J; Wang, Z; Yang, Y; Zhou, D | 1 |
| Abreu-González, P; Argueso, M; Jiménez, A; Lorente, L; Martín, MM; Ramos, L; Riaño-Ruiz, M; Solé-Violán, J | 1 |
| Chen, YY; Jin, X; Li, WJ; Ma, A; Zhang, XM; Zhang, YL; Zhou, H; Zhou, Y | 1 |
| Chen, B; Chen, J; Chen, LD; Li, X; Lin, R; Lin, Y; Tao, J; Yu, K | 1 |
| Chen, R; Cui, L; Kang, N; Liu, X; Wang, H; Wang, L; Wang, X; Xue, J; Yu, J; Zhang, C; Zhang, L; Zhang, N; Zhang, X | 1 |
| Gao, F; Li, P; Shen, M; Teng, F; Wu, J; Zhang, C; Zhang, J | 1 |
| Alimoradi, H; Baery, N; Barzegar-Fallah, A; Barzegar-Fallah, N; Malekmohammadi, N; Parsa, A; Soleymankhani, M | 1 |
| Chen, J; Feng, L; Gu, J; Hou, X; Jia, X; Tan, X; Wang, J; Yang, N | 1 |
| Deng, F; Feng, JC; Hou, S; Liu, XP; Shen, PP; Xie, HY; Zhao, MM | 1 |
| Kim, S; Kwon, J; Lee, JW; Na, JY; Song, K | 1 |
| Gupta, S; Gupta, YK | 1 |
| Fu, Y; Han, W; Huang, D; Li, H; Liu, Q; Liu, Z; Miao, W; Shen, Y; Shi, FD; Shi, K; Yao, Y | 1 |
| Che, LH; Ji, TF; Li, C; Shi, L; Yu, JL | 1 |
| Liu, Y; Wang, C; Wang, Y; Xue, L; Yu, Q; Zhang, H | 1 |
| Aneja, R; Katyal, A; Kumar, M; Kumaran, D; Udayabanu, M | 1 |
| Adachi, N; Arai, T; Irisawa, Y; Liu, K; Nagaro, T | 1 |
| Dong, K; Qiao, H; Wu, L; Xu, W; Yang, J | 1 |
| Carlotti, CG; Colli, BO; Lopes, Lda S; Tirapelli, DP; Tirapelli, LF | 1 |
| Hu, X; Tian, M; Wan, H; Yang, J; Zhang, H; Zhao, C; Zhu, H | 1 |
| Dorotta, IR; Fathali, N; Hasegawa, Y; Jadhav, V; Martin, RD; Matchett, GA; Ostrowski, RP; Sun, X; Zhang, JH | 1 |
| Hao, JL; Jiang, QH; Liu, M; Zhou, LL | 1 |
| Fu, F; Gao, Y; Li, G; Liu, Z; Tian, J; Wang, Y; Zhang, S | 1 |
| Si, YL; Yan, GT; Zhang, JY | 1 |
| Huang, YD; Li, XK; Su, ZJ; Xu, H; Yao, CC; Zhao, W; Zhao, ZY; Zheng, Q | 1 |
| Elango, C; Jayachandaran, KS; Niranjali Devaraj, S | 1 |
| Briyal, S; Gupta, YK; Jagannathan, NR; Sharma, U | 1 |
| Jiang, WL; Tian, JW; Zhang, SP; Zhu, HB | 1 |
| Gong, HL; Li, WP; Li, WZ; Wu, GC; Yin, YY; Zhu, FF | 1 |
| Chen, H; Gan, L; Liu, T; Wang, T; Wang, Z; Yuan, X; Zhang, B; Zheng, Q | 1 |
| Briyal, S; Gulati, A | 1 |
| Sravanthi, R; Thaakur, S | 1 |
| Liu, XH; Loh, KP; Qi, J; Tan, BK; Wei, BG; Zhu, YZ | 1 |
| Lei, SP; Lin, XM; Wang, LL; Yu, SS; Zhao, J; Zhao, Y | 1 |
| Deng, KJ; Xu, JX; Yang, M; Zhou, H | 1 |
| Babu, CS; Kalaivani, P; Kesavanarayanan, KS; Paul, FD; Pramila, B; Priya, RJ; Ranju, V; Sathiya, S; Sunil, AG; Venkhatesh, J | 1 |
| Chen, J; Chen, X; Qin, J | 1 |
| Li, MQ; Lu, Y; Ruan, JS; Wang, AY; Yan, LG; Zhang, L; Zheng, SZ | 1 |
| Chen, L; Liu, H; Ma, S; Yin, H; Zhang, X; Zhao, M | 1 |
| Fang, W; Li, Y; Mao, L; Sun, J | 1 |
| Chauhan, A; Gupta, YK; Jagannathan, NR; Reeta, KH; Sharma, U | 1 |
| Briyal, S; Gulati, A; Leonard, MG | 1 |
| Chen, J; Liang, Y; Meng, C; Tian, SY; Wang, YX; Xing, YJ; Zhang, FG; Zhang, SD; Zhang, XS; Zhang, Y; Zhao, W | 1 |
| Cheng, Y; Sun, J; Wang, H; Yang, C; Zhang, S | 1 |
| Cui, D; Niu, J; Wang, T; Xu, S; Zhang, H; Zhang, R; Zhang, Z | 1 |
| Chauhan, A; Gupta, YK; Jagannathan, NR; Mehra, RD; Reeta, KH; Sharma, U | 1 |
| Chen, L; Dong, L; Li, Y; Liu, Z; Qiao, H; Wang, C; Wang, L; Xing, Y; Zhang, X; Zhu, C | 1 |
| Hyun, SW; Jang, M; Jung, YS; Kim, EJ; Park, SW | 1 |
| Ding, XS; Gu, XS; Han, Q; Huang, H; Huang, HF; Liu, XF; Shen, LH; Wu, EB; Ye, M; Zhang, C | 1 |
| Cen, J; He, L; Ji, BS; Liu, L; Liu, M; Wang, CJ | 1 |
| Cao, XL; Chen, SH; Gong, WH; Hu, XM; Pang, B; Wang, J; Zheng, WX | 1 |
| Hua, Z; Liang, Y; Liu, HG; Ma, YP; Meng, C; Tian, SY; Wang, L; Wang, WS; Wang, YX; Zhang, Y | 1 |
| Dong, H; Guo, C; Tong, L; Wen, A; Xi, M; Yang, H | 1 |
| Chen, WY; Lai, LL; Wan, HT; Yang, JH; Zhang, YY; Zhou, HF; Zhu, ZH | 1 |
| Guo, LJ; Lü, Q; Qian, JQ; Qu, L; Wang, F; Wang, WT | 1 |
| Chaudhary, G; Gupta, YK; Sinha, K | 2 |
| Cai, Z; Lei, M; Lin, S; Rhodes, PG; Zhang, F | 1 |
| Ikeda, M; Suzuki, M; Tabuchi, M; Tomita, T; Umegaki, K | 1 |
| Chen, J; Ding, D; Fu, JH; Hong, Z; Luo, Y; Qin, Z; Zhang, WD; Zhang, X | 1 |
| Fu, F; Geng, M; Jiang, W; Jiang, Y; Liu, K; Tian, J; Wang, C; Yang, J | 1 |
| Briyal, S; Gulati, A; Gupta, YK; Jagannathan, NR; Sharma, U | 1 |
| Yang, J; Zhan, C | 1 |
| Li, GW; Wang, HP; Wang, PY | 1 |
| Gao, F; Song, T; Wu, JM; Zhang, J; Zhou, FY | 1 |
| Kaundal, RK; Sharma, SS | 1 |
| Liu, HZ; Yu, H; Zhou, GL | 1 |
| Cheng, H; Fu, YT; Huang, SS; Hung, LM; Liu, HY; Nien, MW; Tsai, SK; Zhang, FB | 1 |
| Briyal, S; Gulati, A; Gupta, YK | 1 |
| Chen, CJ; Chen, SY; Chiang, AN; Chou, MC; Chuang, YH; Liao, SL; Lin, SY; Pan, HC; Raung, SL; Wang, CC; Wu, CW; Yang, DY; Yen, YJ | 1 |
| Dohare, P; Jaganathanan, NR; Jagannathan, NR; Rathore, P; Ray, A; Ray, M; Sharma, U; Varma, S | 1 |
| Du, YM; Li, CG; Liang, J; Xue, CC; Yu, XQ; Zhou, SF; Zhou, ZW | 1 |
| Altuğ, ME; Aslan, H; Bal, R; Duman, T; Ekici, F; Kontaş, T; Melek, IM; Serarslan, Y | 1 |
| Ding, S; Guan, Y; Li, J; Liu, W; Sun, X; Xu, W; Zhang, JH | 1 |
| Balkan, E; Balkan, S; Gümüşlü, S; Ozben, T; Serteser, M | 1 |
| Cetinalp, E; Göçer, AI; Ildan, F; Isbir, T; Kaya, M; Polat, S; Tuna, M | 1 |
| Chen, YS; Sun, BL; Xia, ZL; Yan, ZW; Yang, MF | 1 |
| Deng, XL; Hou, ZJ; Liu, NF; Ma, XY; Qian, ZY; Wang, HF | 1 |
| Degaonkar, MN; Gupta, YK; Jagannathan, NR; Sinha, K | 1 |
1 trial(s) available for malondialdehyde and Infarction, Middle Cerebral Artery
| Article | Year |
|---|---|
Testosterone enhances functional recovery after stroke through promotion of antioxidant defenses, BDNF levels and neurogenesis in male rats.
Topics: Animals; Antioxidants; Brain Infarction; Brain-Derived Neurotrophic Factor; Disease Models, Animal; Infarction, Middle Cerebral Artery; Locomotion; Male; Malondialdehyde; Neurogenesis; Neuroprotective Agents; Oxidative Stress; Psychomotor Disorders; Rats; Rats, Wistar; Recovery of Function; Testosterone; Time Factors | 2014 |
119 other study(ies) available for malondialdehyde and Infarction, Middle Cerebral Artery
| Article | Year |
|---|---|
Nuclear receptor coactivator 4-mediated ferritinophagy contributes to cerebral ischemia-induced ferroptosis in ischemic stroke.
Topics: Animals; Brain; Cells, Cultured; Ferroptosis; Glutathione; Glutathione Peroxidase; Infarction, Middle Cerebral Artery; Ischemic Stroke; Lipid Peroxidation; Male; Malondialdehyde; Mice, Inbred C57BL; Neurons; Nuclear Receptor Coactivators; Pyrroles; Pyrrolidines; Reperfusion Injury; Ubiquitin Thiolesterase | 2021 |
[Chrysin alleviates cerebral ischemia-reperfusion injury by inhibiting ferroptosis in rats].
Topics: Animals; Brain Ischemia; Cerebral Infarction; Cyclooxygenase 2; Ferroptosis; Infarction, Middle Cerebral Artery; Male; Malondialdehyde; Rats; Rats, Sprague-Dawley; Reperfusion Injury; RNA, Messenger; Signal Transduction | 2023 |
Pharmacodynamic Effect of Ellagic Acid on Ameliorating Cerebral Ischemia/Reperfusion Injury.
Topics: Animals; Brain; Cell Survival; Cytokines; Ellagic Acid; Infarction, Middle Cerebral Artery; Male; Malondialdehyde; Oxidative Stress; PC12 Cells; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Superoxide Dismutase | 2019 |
Attenuating effect of α-pinene on neurobehavioural deficit, oxidative damage and inflammatory response following focal ischaemic stroke in rat.
Topics: Animals; Antioxidants; Bicyclic Monoterpenes; Brain Ischemia; Catalase; Disease Models, Animal; Glutathione; Hippocampus; Infarction, Middle Cerebral Artery; Inflammation; Lipid Peroxidation; Male; Malondialdehyde; Neuroprotective Agents; Oxidation-Reduction; Oxidative Stress; Rats; Rats, Wistar; Reperfusion Injury; Stroke; Superoxide Dismutase | 2019 |
Effects of Inhibition of miR-155-5p in Neural Stem Cell Subarachnoid Transplant on Rats with Cerebral Infarction.
Topics: Animals; Brain; Fetus; Hypoxia-Inducible Factor 1, alpha Subunit; Infarction, Middle Cerebral Artery; Malondialdehyde; MicroRNAs; Neural Stem Cells; Rats, Sprague-Dawley; Subarachnoid Space; Superoxide Dismutase | 2019 |
Non-survivor patients with malignant middle cerebral artery infarction showed persistently high serum malondialdehyde levels.
Topics: Aged; Biomarkers; Female; Humans; Infarction, Middle Cerebral Artery; Male; Malondialdehyde; Middle Aged; Prospective Studies; ROC Curve | 2019 |
Synthesis and biological evaluation of 1,2,4-triazole derivatives as potential neuroprotectant against ischemic brain injury.
Topics: Animals; Female; Infarction, Middle Cerebral Artery; Interleukin-1beta; Male; Malondialdehyde; Membrane Potential, Mitochondrial; Mice; Neuroprotective Agents; NF-E2-Related Factor 2; PC12 Cells; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Superoxide Dismutase; Triazoles; Tumor Necrosis Factor-alpha | 2020 |
Downregulation of Microrna-421 Relieves Cerebral Ischemia/Reperfusion Injuries: Involvement of Anti-apoptotic and Antioxidant Activities.
Topics: Animals; Antagomirs; Antioxidants; Apoptosis; Apoptosis Regulatory Proteins; Brain Ischemia; Cerebral Infarction; Down-Regulation; Drug Evaluation, Preclinical; Glutamic Acid; Infarction, Middle Cerebral Artery; Lipid Peroxidation; Male; Malondialdehyde; Myeloid Cell Leukemia Sequence 1 Protein; Neuroprotective Agents; Oxidative Stress; PC12 Cells; Rats; Rats, Sprague-Dawley; Reperfusion Injury | 2020 |
TREM-1-targeting LP17 attenuates cerebral ischemia-induced neuronal injury by inhibiting oxidative stress and pyroptosis.
Topics: Animals; Brain Ischemia; Cell Line; Cerebral Infarction; Cytokines; Infarction, Middle Cerebral Artery; Malondialdehyde; Mice; Microglia; Neurodegenerative Diseases; Neuroprotective Agents; Oxidative Stress; Pyroptosis; Rats, Sprague-Dawley; Reactive Oxygen Species; Stroke; Triggering Receptor Expressed on Myeloid Cells-1 | 2020 |
Efonidipine Exerts Cerebroprotective Effect by Down-regulation of TGF-β/SMAD-2-Dependent Signaling Pathway in Diabetic Rats.
Topics: Acetylcholinesterase; Animals; Brain; Calcium Channel Blockers; Diabetes Mellitus, Experimental; Dihydropyridines; Infarction, Middle Cerebral Artery; Male; Malondialdehyde; Neuroprotective Agents; Nitrites; Nitrophenols; Organophosphorus Compounds; Oxidative Stress; Rats; Rats, Sprague-Dawley; Signal Transduction; Smad2 Protein; Transforming Growth Factor beta; Vascular Endothelial Growth Factor A | 2021 |
Dynorphin A (1-8) inhibits oxidative stress and apoptosis in MCAO rats, affording neuroprotection through NMDA receptor and κ-opioid receptor channels.
Topics: Animals; Apoptosis; Blood-Brain Barrier; Caspase 3; Dynorphins; Infarction, Middle Cerebral Artery; Malondialdehyde; Neuroprotective Agents; Oxidative Stress; Peptide Fragments; Rats; Receptors, N-Methyl-D-Aspartate; Receptors, Opioid, kappa; Superoxide Dismutase | 2021 |
Effects of Noggin-Transfected Neural Stem Cells on Neural Functional Recovery and Underlying Mechanism in Rats with Cerebral Ischemia Reperfusion Injury.
Topics: Adenoviridae; Animals; Apoptosis; Bone Morphogenetic Protein 4; Brain; Carrier Proteins; Cell Proliferation; Cells, Cultured; Disease Models, Animal; Fibroblast Growth Factor 2; Genetic Therapy; Genetic Vectors; Infarction, Middle Cerebral Artery; Male; Malondialdehyde; Nerve Degeneration; Neural Stem Cells; Neurogenesis; Rats, Wistar; Recovery of Function; Reperfusion Injury; Superoxide Dismutase; Time Factors; Transfection; Vascular Endothelial Growth Factor A | 2017 |
Fullerenol nanoparticles decrease ischaemia-induced brain injury and oedema through inhibition of oxidative damage and aquaporin-1 expression in ischaemic stroke.
Topics: Animals; Aquaporin 1; Brain Edema; Brain Infarction; Brain Injuries; Cerebrovascular Circulation; Disease Models, Animal; Fullerenes; Gene Expression Regulation; Infarction, Middle Cerebral Artery; Male; Malondialdehyde; Nanoparticles; Neurologic Examination; Nitrates; Oxidative Stress; Rats; Rats, Wistar; Statistics, Nonparametric | 2017 |
DhHP‑6 attenuates cerebral ischemia‑reperfusion injury in rats through the inhibition of apoptosis.
Topics: Animals; Apoptosis; Brain; Caspase 3; Catalase; Disease Models, Animal; Glutathione Peroxidase; Hemin; Infarction, Middle Cerebral Artery; Male; Malondialdehyde; Neuroprotective Agents; Oxidative Stress; Proto-Oncogene Proteins c-akt; Proto-Oncogene Proteins c-bcl-2; Rats; Rats, Wistar; Reactive Oxygen Species; Reperfusion Injury; Stroke; Superoxide Dismutase; Up-Regulation | 2017 |
Xueshuantong injection (lyophilized) combined with salvianolate lyophilized injection protects against focal cerebral ischemia/reperfusion injury in rats through attenuation of oxidative stress.
Topics: Animals; Antioxidants; Astrocytes; Behavior, Animal; Biomarkers; Cerebrovascular Circulation; Disease Models, Animal; Drugs, Chinese Herbal; Freeze Drying; Hippocampus; Infarction, Middle Cerebral Artery; Injections, Intravenous; Kelch-Like ECH-Associated Protein 1; Male; Malondialdehyde; Medicine, Chinese Traditional; Microglia; Neuroprotective Agents; NF-E2-Related Factor 2; Oxidative Stress; Plant Extracts; Rats, Wistar; Reactive Oxygen Species; Reperfusion Injury; Signal Transduction; Time Factors | 2018 |
The protective effect and its mechanism of 3-n-butylphthalide pretreatment on cerebral ischemia reperfusion injury in rats.
Topics: Animals; Apoptosis; Benzofurans; Blood-Brain Barrier; Body Water; Brain Ischemia; Caspase 3; Hippocampus; Infarction, Middle Cerebral Artery; Malondialdehyde; MAP Kinase Signaling System; Neurons; Neuroprotective Agents; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Reperfusion Injury; Superoxide Dismutase | 2017 |
Arachidonic acid attenuates brain damage in a rat model of ischemia/reperfusion by inhibiting inflammatory response and oxidative stress.
Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Arachidonic Acid; Behavior, Animal; Cytoprotection; Disease Models, Animal; Dose-Response Relationship, Drug; Glutathione Peroxidase; Hippocampus; Infarction, Middle Cerebral Artery; Inflammation Mediators; Interleukin-6; Male; Malondialdehyde; Maze Learning; Neuroprotective Agents; Oxidative Stress; Rats, Wistar; Reperfusion Injury; Superoxide Dismutase; Time Factors; Tumor Necrosis Factor-alpha | 2018 |
The bone marrow mononuclear cells reduce the oxidative stress of cerebral infarction through PI3K/AKT/NRF2 signaling pathway.
Topics: Animals; Bone Marrow; Brain Ischemia; Cerebral Infarction; Infarction, Middle Cerebral Artery; Male; Malondialdehyde; NF-E2-Related Factor 2; Oxidative Stress; Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins c-akt; Rats; Rats, Sprague-Dawley; Signal Transduction | 2017 |
Impact of Early High-protein Diet on Neurofunctional Recovery in Rats with Ischemic Stroke.
Topics: Animals; Brain; Brain Ischemia; Diet, High-Protein; Disease Models, Animal; Infarction, Middle Cerebral Artery; Male; Malondialdehyde; Neuroprotective Agents; Nitric Oxide Synthase Type II; Oxidative Stress; Rats; Rats, Sprague-Dawley; Stroke; Superoxide Dismutase | 2018 |
Citalopram attenuated neurobehavioral, biochemical, and metabolic alterations in transient middle cerebral artery occlusion model of stroke in male Wistar rats.
Topics: Animals; Brain; Brain Ischemia; Citalopram; Glutathione; Infarction, Middle Cerebral Artery; Male; Malondialdehyde; Neuroprotective Agents; Oxidative Stress; Rats; Rats, Wistar; Rotarod Performance Test; Stroke | 2018 |
Serum melatonin levels are associated with mortality in patients with malignant middle cerebral artery infarction.
Topics: Aged; Antioxidants; Female; Humans; Infarction, Middle Cerebral Artery; Malondialdehyde; Melatonin; Middle Aged; Oxidative Stress; Prognosis; Prospective Studies; Stroke | 2018 |
Neuroprotective effect of vildagliptin against cerebral ischemia in rats.
Topics: Adamantane; Animals; Caspase 3; Dipeptidyl-Peptidase IV Inhibitors; Glutathione; Infarction, Middle Cerebral Artery; Locomotion; Male; Malondialdehyde; Neuroprotective Agents; Nitriles; Phosphatidylinositol 3-Kinases; Pyrrolidines; Rats, Wistar; TOR Serine-Threonine Kinases; Vildagliptin | 2018 |
Elevated Serum Potassium Concentration Alleviates Cerebral Ischemia-Reperfusion Injury via Mitochondrial Preservation.
Topics: Adenosine Triphosphate; Animals; Apoptosis; Brain; Caspase 3; Electron Transport Complex IV; Infarction, Middle Cerebral Artery; Male; Malondialdehyde; Mitochondria; Mitochondrial Membrane Transport Proteins; Mitochondrial Permeability Transition Pore; Potassium; Potassium Chloride; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Reperfusion Injury; Superoxide Dismutase | 2018 |
Neuroprotective Effects of Radix Scrophulariae on Cerebral Ischemia and Reperfusion Injury via MAPK Pathways.
Topics: Acanthaceae; Animals; Apoptosis; bcl-2-Associated X Protein; Brain Ischemia; Catalase; Cell Line, Tumor; Cell Survival; Disease Models, Animal; Glutathione; Infarction, Middle Cerebral Artery; L-Lactate Dehydrogenase; Male; Malondialdehyde; Membrane Potential, Mitochondrial; Mice; Neuroprotective Agents; Nitric Oxide; Oxidative Stress; PC12 Cells; Plant Extracts; Rats; Reperfusion Injury; Stroke; Superoxide Dismutase | 2018 |
Protective effects of tetramethylpyrazine analogue Z-11 on cerebral ischemia reperfusion injury.
Topics: Animals; Brain; Glutathione; Heme Oxygenase (Decyclizing); Infarction, Middle Cerebral Artery; Male; Malondialdehyde; Neuroprotective Agents; NF-E2-Related Factor 2; Pyrazines; Rats, Wistar; Reactive Oxygen Species; Reperfusion Injury; Superoxide Dismutase | 2019 |
A novel, highly-water-soluble apigenin derivative provides neuroprotection following ischemia in male rats by regulating the ERK/Nrf2/HO-1 pathway.
Topics: Animals; Antioxidants; Apigenin; Brain; Cell Line; Cell Survival; Extracellular Signal-Regulated MAP Kinases; Heme Oxygenase (Decyclizing); Humans; Infarction, Middle Cerebral Artery; Male; Malondialdehyde; Neuroprotective Agents; NF-E2-Related Factor 2; Rats; Rats, Sprague-Dawley; Solubility; Superoxide Dismutase; Water | 2019 |
A NMR-Based Metabonomics Approach to Determine Protective Effect of a Combination of Multiple Components Derived from Naodesheng on Ischemic Stroke Rats.
Topics: Animals; Apigenin; Brain; Brain Ischemia; Drugs, Chinese Herbal; Ginsenosides; Infarction, Middle Cerebral Artery; Isoflavones; L-Lactate Dehydrogenase; Magnetic Resonance Spectroscopy; Male; Malondialdehyde; Metabolomics; Oxidative Stress; Rats; Rats, Wistar; Stroke; Superoxide Dismutase | 2019 |
Neuroprotective effect of Danshensu derivatives as anti-ischaemia agents on SH-SY5Y cells and rat brain.
Topics: Animals; Apoptosis; Apoptosis Regulatory Proteins; Cell Line, Tumor; Cell Shape; Cell Survival; Cerebral Cortex; Drug Evaluation, Preclinical; Drugs, Chinese Herbal; Glutathione; Glutathione Peroxidase; Humans; Hydrogen Peroxide; Infarction, Middle Cerebral Artery; L-Lactate Dehydrogenase; Lactates; Male; Malondialdehyde; Neuroprotective Agents; Rats; Rats, Sprague-Dawley; Superoxide Dismutase | 2013 |
7,8-dihydroxyflavone, a small-molecule tropomyosin-related kinase B (TrkB) agonist, attenuates cerebral ischemia and reperfusion injury in rats.
Topics: Animals; Drug Evaluation, Preclinical; Enzyme Activation; Enzyme Activators; Flavones; Glutathione; Glutathione Peroxidase; Infarction, Middle Cerebral Artery; Male; Malondialdehyde; Nitric Oxide; Oxidative Stress; Rats; Rats, Sprague-Dawley; Receptor, trkB; Reperfusion Injury; Superoxide Dismutase | 2014 |
The effects of vagal nerve stimulation in focal cerebral ischemia and reperfusion model.
Topics: Animals; Behavior, Animal; Brain Ischemia; Cerebral Infarction; Coloring Agents; Electrodes, Implanted; Glutathione; Infarction, Middle Cerebral Artery; Male; Malondialdehyde; Oxidative Stress; Rats; Rats, Wistar; Reperfusion Injury; Superoxide Dismutase; Tetrazolium Salts; Vagus Nerve Stimulation | 2013 |
Cerebroprotective effect of Moringa oleifera against focal ischemic stroke induced by middle cerebral artery occlusion.
Topics: Animals; Brain; Brain Ischemia; Disease Models, Animal; Glutathione Peroxidase; Infarction, Middle Cerebral Artery; Male; Malondialdehyde; Moringa oleifera; Neuroprotective Agents; Oxidative Stress; Phytotherapy; Plant Extracts; Plant Leaves; Rats; Rats, Wistar; Recovery of Function; Stroke; Superoxide Dismutase | 2013 |
Rapamycin attenuates mitochondrial dysfunction via activation of mitophagy in experimental ischemic stroke.
Topics: Adaptor Proteins, Signal Transducing; Adenosine Triphosphate; Animals; Apoptosis Regulatory Proteins; Autophagy; Beclin-1; Blotting, Western; Brain; Brain Ischemia; Immunohistochemistry; Immunosuppressive Agents; Infarction, Middle Cerebral Artery; Male; Malondialdehyde; Membrane Potential, Mitochondrial; Membrane Proteins; Microscopy, Electron, Transmission; Microtubule-Associated Proteins; Mitochondria; Mitophagy; Protein Transport; Rats; Rats, Sprague-Dawley; Sequestosome-1 Protein; Sirolimus; Stroke | 2014 |
Anemonin alleviates nerve injury after cerebral ischemia and reperfusion (i/r) in rats by improving antioxidant activities and inhibiting apoptosis pathway.
Topics: Animals; Apoptosis; Blood-Brain Barrier; Catalase; Furans; Glutathione; Infarction, Middle Cerebral Artery; Male; Malondialdehyde; Neuroprotective Agents; Rats; Rats, Wistar; Reactive Oxygen Species; Sodium-Potassium-Exchanging ATPase; Superoxide Dismutase | 2014 |
Effect of hirulog-like peptide on middle cerebral artery occlusion-induced brain injury in mice.
Topics: Animals; Antithrombins; Apoptosis; Blotting, Western; Brain; Disease Models, Animal; Down-Regulation; Heparin, Low-Molecular-Weight; Hirudins; Immunohistochemistry; Infarction, Middle Cerebral Artery; Male; Malondialdehyde; Mice, Inbred ICR; Motor Activity; Neuroprotective Agents; Peptide Fragments; Receptors, Thrombin; Rotarod Performance Test; Severity of Illness Index | 2014 |
[Study on prevention effect of huoluotongnao tablet on stroke (II)].
Topics: Animals; Brain; Brain Ischemia; Disease Models, Animal; Drugs, Chinese Herbal; Infarction, Middle Cerebral Artery; Male; Malondialdehyde; Neuroprotective Agents; Plants, Medicinal; Random Allocation; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Superoxide Dismutase; Tablets | 2014 |
Equol is neuroprotective during focal cerebral ischemia and reperfusion that involves p-Src and gp91(phox).
Topics: Animals; Brain Infarction; Disease Models, Animal; Equol; Gene Expression Regulation; Glucose; Hypoxia; Infarction, Middle Cerebral Artery; L-Lactate Dehydrogenase; Male; Malondialdehyde; Membrane Glycoproteins; NADPH Oxidase 2; NADPH Oxidases; Nervous System Diseases; Neuroprotective Agents; PC12 Cells; Phosphorylation; Proto-Oncogene Proteins pp60(c-src); Rats; Rats, Sprague-Dawley; Reperfusion | 2014 |
Paeonol pretreatment attenuates cerebral ischemic injury via upregulating expression of pAkt, Nrf2, HO-1 and ameliorating BBB permeability in mice.
Topics: Acetophenones; Animals; Blood-Brain Barrier; Capillary Permeability; Claudin-5; Disease Models, Animal; Heme Oxygenase-1; Infarction, Middle Cerebral Artery; Male; Malondialdehyde; Mice; Mice, Inbred ICR; Neuroprotective Agents; NF-E2-Related Factor 2; Proto-Oncogene Proteins c-akt; Spectrum Analysis; Superoxide Dismutase; Up-Regulation | 2014 |
Targeting thioredoxin-1 with siRNA exacerbates oxidative stress injury after cerebral ischemia/reperfusion in rats.
Topics: Animals; Brain; Brain Edema; Brain Ischemia; Disease Models, Animal; Gene Knockdown Techniques; Infarction, Middle Cerebral Artery; Male; Malondialdehyde; NF-E2-Related Factor 2; Oxidative Stress; Peroxiredoxins; Random Allocation; Rats, Sprague-Dawley; Reperfusion Injury; RNA, Messenger; RNA, Small Interfering; Superoxide Dismutase; Thioredoxins | 2015 |
Posttreatment with 11-Keto-β-Boswellic Acid Ameliorates Cerebral Ischemia-Reperfusion Injury: Nrf2/HO-1 Pathway as a Potential Mechanism.
Topics: Animals; Antioxidants; Apoptosis; Astrocytes; Boswellia; Brain; Brain Damage, Chronic; Cell Hypoxia; Cells, Cultured; Drug Evaluation, Preclinical; Glucose; Heme Oxygenase (Decyclizing); Infarction, Middle Cerebral Artery; Male; Malondialdehyde; Nerve Tissue Proteins; Neuroprotective Agents; NF-E2-Related Factor 2; Oxidative Stress; Phytotherapy; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Signal Transduction; Superoxide Dismutase; Triterpenes | 2015 |
Neuroprotective activity of creatylglycine ethyl ester fumarate.
Topics: Adenosine Triphosphate; Animals; Antioxidants; Behavior, Animal; Brain; Cell Survival; Creatine Kinase; Cytoprotection; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Partial Agonism; Drug Stability; Energy Metabolism; Excitatory Amino Acid Agonists; Fumarates; Half-Life; Infarction, Middle Cerebral Artery; Lactic Acid; Male; Malondialdehyde; Neurons; Neuroprotective Agents; Oxidative Stress; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Reperfusion Injury; Superoxide Dismutase | 2015 |
Protective effect of rhGLP-1 (7-36) on brain ischemia/reperfusion damage in diabetic rats.
Topics: Animals; Blood Glucose; Brain; Brain Ischemia; Diabetes Mellitus, Experimental; Dose-Response Relationship, Drug; Glucagon-Like Peptide 1; Glutathione Peroxidase; Hypoglycemic Agents; Infarction, Middle Cerebral Artery; Male; Malondialdehyde; Neuroprotective Agents; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Peptide Fragments; Random Allocation; Rats, Sprague-Dawley; Reperfusion Injury; Severity of Illness Index; Superoxide Dismutase | 2015 |
Upregulation of neuroglobin expression and changes in serum redox indices in a rat model of middle cerebral artery occlusion.
Topics: Animals; Cerebral Cortex; Disease Models, Animal; Globins; Hippocampus; Hypoxia-Inducible Factor 1, alpha Subunit; Immunohistochemistry; Infarction, Middle Cerebral Artery; Male; Malondialdehyde; Nerve Tissue Proteins; Neuroglobin; Rats; Rats, Sprague-Dawley; Real-Time Polymerase Chain Reaction; RNA, Messenger; Superoxide Dismutase; Up-Regulation | 2015 |
Serum malondialdehyde levels in patients with malignant middle cerebral artery infarction are associated with mortality.
Topics: Adult; Aged; Biomarkers; Female; Glasgow Coma Scale; Heart Neoplasms; Humans; Infarction, Middle Cerebral Artery; Intensive Care Units; Lipid Peroxidation; Male; Malondialdehyde; Middle Aged; Prognosis; Prospective Studies; ROC Curve; Stroke; Survivors | 2015 |
Orally administrated pterostilbene attenuates acute cerebral ischemia-reperfusion injury in a dose- and time-dependent manner in mice.
Topics: Administration, Oral; Animals; Apoptosis; Blood-Brain Barrier; Brain Ischemia; Cell Survival; Dose-Response Relationship, Drug; Infarction, Middle Cerebral Artery; Male; Malondialdehyde; Mice; Neuroprotective Agents; Oxidative Stress; Postural Balance; Psychomotor Performance; Reperfusion Injury; Stilbenes; Superoxide Dismutase | 2015 |
Electroacupuncture ameliorates learning and memory in rats with cerebral ischemia-reperfusion injury by inhibiting oxidative stress and promoting p-CREB expression in the hippocampus.
Topics: Animals; Apoptosis; Cyclic AMP Response Element-Binding Protein; Electroacupuncture; Gene Expression; Glutathione Peroxidase; Hippocampus; Infarction, Middle Cerebral Artery; Learning; Male; Malondialdehyde; Memory Disorders; Oxidative Stress; Phosphorylation; Protein Processing, Post-Translational; Rats, Sprague-Dawley; Reperfusion Injury; Superoxide Dismutase | 2015 |
Protective effect of Naoxintong against cerebral ischemia reperfusion injury in mice.
Topics: Animals; Brain; Drugs, Chinese Herbal; Infarction, Middle Cerebral Artery; Male; Malondialdehyde; MAP Kinase Signaling System; Medicine, Chinese Traditional; Mice; Neurologic Examination; Neuroprotective Agents; NF-kappa B; Phytotherapy; Reperfusion Injury; Scavenger Receptors, Class E; Superoxide Dismutase; Water | 2016 |
An Antagomir to MicroRNA-106b-5p Ameliorates Cerebral Ischemia and Reperfusion Injury in Rats Via Inhibiting Apoptosis and Oxidative Stress.
Topics: Animals; Antagomirs; Antioxidants; Apoptosis; Base Sequence; bcl-2-Associated X Protein; Brain Ischemia; Cerebral Cortex; Down-Regulation; Gene Expression Regulation; Glutamic Acid; Infarction, Middle Cerebral Artery; Male; Malondialdehyde; MicroRNAs; Myeloid Cell Leukemia Sequence 1 Protein; Oxidative Stress; PC12 Cells; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Superoxide Dismutase; Up-Regulation | 2017 |
Kelussia odoratissima Mozaff attenuates thromboembolic brain injury, possibly due to its Z-ligustilide content.
Topics: 4-Butyrolactone; Animals; Antioxidants; Apiaceae; Brain Edema; Catalase; Cerebral Cortex; Disease Models, Animal; Glutathione; Infarction, Middle Cerebral Artery; Male; Malondialdehyde; Oxidative Stress; Plant Extracts; Rats; Rats, Wistar; Stroke; Superoxide Dismutase; Tumor Necrosis Factor-alpha | 2016 |
Combination of Ligusticum chuanxiong and Radix Paeoniae ameliorate focal cerebral ischemic in MCAO rats via endoplasmic reticulum stress-dependent apoptotic signaling pathway.
Topics: Animals; Apoptosis; bcl-2-Associated X Protein; Brain; Catalase; Endoplasmic Reticulum Stress; Glutathione; Glutathione Peroxidase; Infarction, Middle Cerebral Artery; Ligusticum; Male; Malondialdehyde; Matrix Metalloproteinase 9; Neuroprotective Agents; Paeonia; Plasminogen Activator Inhibitor 1; Plasminogen Activators; Proto-Oncogene Proteins c-bcl-2; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; RNA, Messenger; Signal Transduction; Superoxide Dismutase; Tissue Inhibitor of Metalloproteinase-1; Vascular Endothelial Growth Factor A | 2016 |
Mechanism of Mitochondrial Connexin43's Protection of the Neurovascular Unit under Acute Cerebral Ischemia-Reperfusion Injury.
Topics: Animals; Apoptosis; Cerebral Cortex; Connexin 43; Infarction, Middle Cerebral Artery; Male; Malondialdehyde; Mitochondria; Mitochondrial Proteins; Protein Kinase C; Rats; Rats, Wistar; Superoxide Dismutase | 2016 |
Pretreatment of 6-shogaol attenuates oxidative stress and inflammation in middle cerebral artery occlusion-induced mice.
Topics: Animals; Behavior, Animal; Catechols; Cytokines; Gene Expression Regulation, Enzymologic; Infarction, Middle Cerebral Artery; Inflammation; Male; Malondialdehyde; Mice; Mice, Inbred C57BL; Mitogen-Activated Protein Kinases; Oxidative Stress; Reactive Oxygen Species; Receptors, Leukotriene; Signal Transduction | 2016 |
Combination of Zizyphus jujuba and silymarin showed better neuroprotective effect as compared to single agent in MCAo-induced focal cerebral ischemia in rats.
Topics: Animals; Anticonvulsants; Antioxidants; Brain; Brain Ischemia; Disease Models, Animal; Drug Therapy, Combination; Infarction, Middle Cerebral Artery; Male; Malondialdehyde; Neuroprotective Agents; Oxidative Stress; Rats; Rats, Wistar; Silymarin; Stroke; Superoxide Dismutase; Ziziphus | 2017 |
Dimethyl Fumarate and Monomethyl Fumarate Promote Post-Ischemic Recovery in Mice.
Topics: Animals; Brain Edema; Calcium-Binding Proteins; Dimethyl Fumarate; Disease Models, Animal; Dose-Response Relationship, Drug; Fumarates; Glial Fibrillary Acidic Protein; Glutathione; Immunosuppressive Agents; Infarction, Middle Cerebral Artery; Maleates; Malondialdehyde; Mice; Mice, Inbred C57BL; Microfilament Proteins; Neurologic Examination; Neuroprotective Agents; NF-E2-Related Factor 2; Oxidative Stress; Recovery of Function; Reperfusion Injury; Time Factors | 2016 |
Effects of the TLR4 signaling pathway on apoptosis of neuronal cells in diabetes mellitus complicated with cerebral infarction in a rat model.
Topics: Animals; Apoptosis; Apoptosis Regulatory Proteins; Brain; Diabetes Mellitus, Experimental; Infarction, Middle Cerebral Artery; Interleukin-1beta; Male; Malondialdehyde; Neurons; Rats, Sprague-Dawley; Signal Transduction; Superoxide Dismutase; Toll-Like Receptor 4; Tumor Necrosis Factor-alpha | 2017 |
Effect of large dose hyperbaric oxygenation therapy on prognosis and oxidative stress of acute permanent cerebral ischemic stroke in rats.
Topics: Acute Disease; Animals; Brain; Brain Ischemia; Cerebral Infarction; Disease Models, Animal; Dose-Response Relationship, Drug; Hyperbaric Oxygenation; Infarction, Middle Cerebral Artery; Male; Malondialdehyde; Nitric Oxide; Oxidative Stress; Oxygen; Oxygen Consumption; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Recovery of Function; Stroke; Tetrazolium Salts; Time Factors; Treatment Outcome | 2008 |
Involvement of angiotensin converting enzyme in cerebral hypoperfusion induced anterograde memory impairment and cholinergic dysfunction in rats.
Topics: Acetylcholine; Amnesia, Anterograde; Analysis of Variance; Animals; Avoidance Learning; Behavior, Animal; Captopril; Cholinesterases; Disease Models, Animal; Enzyme Inhibitors; Gene Expression Regulation; Hippocampus; Infarction, Middle Cerebral Artery; Lipid Peroxidation; Male; Malondialdehyde; Maze Learning; Peptidyl-Dipeptidase A; Rats; Rats, Sprague-Dawley; Reaction Time; Time Factors | 2008 |
Alleviation of ischemia-induced brain edema by activation of the central histaminergic system in rats.
Topics: Animals; Blood Cell Count; Body Water; Brain Chemistry; Brain Edema; Brain Ischemia; Cerebral Cortex; Cytokines; Histamine; Histamine Agonists; Histamine Antagonists; Histidine; Infarction, Middle Cerebral Artery; Male; Malondialdehyde; Microdialysis; Neostriatum; Piperidines; Rats; Rats, Wistar; Superoxide Dismutase | 2008 |
Neuroprotective effects of Tanshinone IIA on permanent focal cerebral ischemia in mice.
Topics: Abietanes; Animals; Astrocytes; Brain; Brain Ischemia; Cells, Cultured; Cerebral Infarction; Drugs, Chinese Herbal; Hydrogen Peroxide; Infarction, Middle Cerebral Artery; Male; Malondialdehyde; Mice; Mice, Inbred ICR; Neuroprotective Agents; NF-kappa B; Nitric Oxide; Nitric Oxide Synthase Type II; Oxidative Stress; Phenanthrenes; Rats; Rats, Sprague-Dawley; Superoxide Dismutase | 2009 |
Biochemical evaluation of focal non-reperfusion cerebral ischemia by middle cerebral artery occlusion in rats.
Topics: Adenosine Triphosphate; Animals; Apoptosis; Caspase 3; Infarction, Middle Cerebral Artery; Lipid Peroxidation; Male; Malondialdehyde; Oxidative Stress; Rats; Rats, Wistar; Time Factors | 2008 |
Protective effect of chuanxiongzine-puerarin in a rat model of transient middle cerebral artery occlusion-induced focal cerebral ischemia.
Topics: Animals; Antioxidants; Brain; Gene Expression Regulation; Glucose; Infarction, Middle Cerebral Artery; Interleukin-1; Ischemic Attack, Transient; Isoflavones; Male; Malondialdehyde; Nervous System Diseases; Neuroprotective Agents; Nitric Oxide; Pyrazines; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Superoxide Dismutase; Synaptophysin; Tetrazolium Salts | 2008 |
Hydrogen gas is ineffective in moderate and severe neonatal hypoxia-ischemia rat models.
Topics: Analysis of Variance; Animals; Animals, Newborn; Body Weight; Brain; Disease Models, Animal; Hydrogen; Hypoxia-Ischemia, Brain; Infarction, Middle Cerebral Artery; Lipid Peroxidation; Male; Malondialdehyde; Neuropsychological Tests; Photomicrography; Random Allocation; Rats; Rats, Sprague-Dawley | 2009 |
Protective effect of total flavones of Abelmoschus manihot L. Medic against poststroke depression injury in mice and its action mechanism.
Topics: Abelmoschus; Animals; Behavior, Animal; Brain Injuries; Brain-Derived Neurotrophic Factor; Cyclic AMP Response Element-Binding Protein; Depressive Disorder; Drugs, Chinese Herbal; Flavones; Glutathione Peroxidase; Hippocampus; Infarction, Middle Cerebral Artery; Lipid Peroxidation; Male; Malondialdehyde; Mice; Phytotherapy; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Stroke; Superoxide Dismutase | 2009 |
SMND-309, a novel derivate of salvianolic acid B, ameliorates cerebral infarction in rats: characterization and role.
Topics: Adenosine Triphosphate; Analysis of Variance; Animals; Brain; Caffeic Acids; Dose-Response Relationship, Drug; Electron Transport; Energy Metabolism; Glutathione Peroxidase; Infarction, Middle Cerebral Artery; Male; Malondialdehyde; Membrane Potential, Mitochondrial; Mitochondria; Neuroprotective Agents; Rats; Rats, Sprague-Dawley; Severity of Illness Index; Superoxide Dismutase; Time Factors | 2009 |
[Protective effect of leptin against cerebral ischemia/reperfusion injury in mice].
Topics: Animals; Brain; Brain Ischemia; Infarction, Middle Cerebral Artery; L-Lactate Dehydrogenase; Leptin; Male; Malondialdehyde; Mice; Nitric Oxide; Reperfusion Injury; Time Factors | 2009 |
Protective effects of mutant of acidic fibroblast growth factor against cerebral ischaemia-reperfusion injury in rats.
Topics: Animals; Brain Edema; Brain Ischemia; Cerebral Infarction; Dose-Response Relationship, Drug; Fibroblast Growth Factor 1; Infarction, Middle Cerebral Artery; Ligation; Lipid Peroxidation; Male; Malondialdehyde; Middle Cerebral Artery; Random Allocation; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Superoxide Dismutase | 2009 |
Hawthorn extract reduces infarct volume and improves neurological score by reducing oxidative stress in rat brain following middle cerebral artery occlusion.
Topics: Animals; Antioxidants; Brain Infarction; Crataegus; Glutathione; Infarction, Middle Cerebral Artery; Lipid Peroxidation; Male; Malondialdehyde; Neuroprotective Agents; Neuropsychological Tests; Nitric Oxide; Oxidation-Reduction; Oxidative Stress; Plant Extracts; Rats; Rats, Sprague-Dawley | 2009 |
Effect of vineatrol in focal cerebral ischemia in rats.
Topics: Animals; Brain Ischemia; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Administration Schedule; Glutathione; Infarction, Middle Cerebral Artery; Male; Malondialdehyde; Motor Activity; Oxidative Stress; Phenols; Rats; Rats, Wistar; Stroke; Superoxide Dismutase | 2009 |
Cornin ameliorates cerebral infarction in rats by antioxidant action and stabilization of mitochondrial function.
Topics: Animals; Brain; Calcium; Cell Respiration; Electron Transport; Glutathione Peroxidase; Infarction, Middle Cerebral Artery; Iridoid Glycosides; Iridoids; Male; Malondialdehyde; Membrane Fluidity; Mitochondria; Mitochondrial Membranes; Neuroprotective Agents; Phospholipids; Phytotherapy; Plant Extracts; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Reperfusion Injury; Superoxide Dismutase; Verbena; Water | 2010 |
Protective effect of astragaloside on focal cerebral ischemia/reperfusion injury in rats.
Topics: Animals; Brain; Brain Ischemia; Cerebral Infarction; Drugs, Chinese Herbal; Infarction, Middle Cerebral Artery; L-Lactate Dehydrogenase; Lactates; Male; Malondialdehyde; Nerve Growth Factor; Neuroprotective Agents; Nitric Oxide; Nitric Oxide Synthase Type II; Rats; Rats, Sprague-Dawley; Receptor, trkA; Reperfusion Injury; Reverse Transcriptase Polymerase Chain Reaction; Saponins; Superoxide Dismutase; Time Factors; Triterpenes; Water | 2010 |
Shikonin protects mouse brain against cerebral ischemia/reperfusion injury through its antioxidant activity.
Topics: Animals; Antioxidants; Biomarkers; Brain Ischemia; Dose-Response Relationship, Drug; Glutathione; Infarction, Middle Cerebral Artery; Male; Malondialdehyde; Mice; Mitochondria; Naphthoquinones; Neuroprotective Agents; Oxidative Stress; Oxidoreductases; Protein Carbonylation; Random Allocation; Reactive Oxygen Species; Reperfusion Injury; Up-Regulation | 2010 |
Endothelin-A receptor antagonist BQ123 potentiates acetaminophen induced hypothermia and reduces infarction following focal cerebral ischemia in rats.
Topics: Acetaminophen; Animals; Antipyretics; Brain Ischemia; Disease Models, Animal; Drug Synergism; Endothelin A Receptor Antagonists; Glutathione; Hypothermia, Induced; Infarction, Middle Cerebral Artery; Male; Malondialdehyde; Oxidative Stress; Peptides, Cyclic; Rats; Rats, Sprague-Dawley; Stroke | 2010 |
Neuroprotective effect of Spirulina in cerebral ischemia-reperfusion injury in rats.
Topics: Analysis of Variance; Animals; Antioxidants; Brain; Catalase; Glutathione; Infarction, Middle Cerebral Artery; Lipid Peroxidation; Male; Malondialdehyde; Random Allocation; Rats; Reperfusion Injury; Spirulina; Superoxide Dismutase | 2010 |
Leonurine protects middle cerebral artery occluded rats through antioxidant effect and regulation of mitochondrial function.
Topics: Adenosine Triphosphate; Animals; Antioxidants; Brain; Gallic Acid; Glutathione Peroxidase; Infarction, Middle Cerebral Artery; Male; Malondialdehyde; Mitochondria; Models, Animal; Oxidative Stress; Plant Extracts; Rats; Rats, Sprague-Dawley; Rats, Wistar; Reactive Oxygen Species; Superoxide Dismutase | 2010 |
4-hydroxybenzyl alcohol ameliorates cerebral injury in rats by antioxidant action.
Topics: Animals; Antioxidants; Benzyl Alcohols; Brain Injuries; Infarction, Middle Cerebral Artery; Male; Malondialdehyde; NAD(P)H Dehydrogenase (Quinone); Neuroprotective Agents; Neuropsychological Tests; Oxidative Stress; Rats; Rats, Sprague-Dawley; Superoxide Dismutase | 2011 |
Antioxidant activities of Dracocephalum tanguticum maxim extract and its up-regulation on the expression of neurotrophic factors in a rat model of permanent focal cerebral ischemia.
Topics: Animals; Antioxidants; Behavior, Animal; Brain; Brain Ischemia; Brain-Derived Neurotrophic Factor; Disease Models, Animal; Flavonoids; Infarction, Middle Cerebral Artery; Lamiaceae; Male; Malondialdehyde; Nerve Growth Factors; Neurotrophin 3; Phytotherapy; Plant Extracts; Rats; Rats, Sprague-Dawley; RNA, Messenger; Up-Regulation | 2011 |
Total oligomeric flavonoids of Cyperus rotundus ameliorates neurological deficits, excitotoxicity and behavioral alterations induced by cerebral ischemic-reperfusion injury in rats.
Topics: Animals; Astrocytes; Behavior, Animal; Brain Ischemia; Cyperus; Flavonoids; Humans; Infarction, Middle Cerebral Artery; Male; Malondialdehyde; Medicine, Ayurvedic; Neurons; Neuroprotective Agents; Oxidative Stress; Rats; Rats, Sprague-Dawley; Reperfusion Injury | 2011 |
Effects of polysaccharides of the Euphoria Longan (Lour.) Steud on focal cerebral ischemia/reperfusion injury and its underlying mechanism.
Topics: Animals; Brain Ischemia; Infarction, Middle Cerebral Artery; Malondialdehyde; Oxidative Stress; Plant Extracts; Polysaccharides; Rats; Reperfusion Injury; Sapindaceae | 2011 |
Injectable caltrop fruit saponin protects against ischemia-reperfusion injury in rat brain.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Anti-Inflammatory Agents; Calcium Channel Blockers; Cerebral Infarction; Cerebrum; Endothelins; Forelimb; Fruit; Infarction, Middle Cerebral Artery; Injections; Male; Malondialdehyde; Neuroprotective Agents; Nitric Oxide; Phytotherapy; Plant Extracts; Rats; Rats, Wistar; Reperfusion Injury; Saponins; Superoxide Dismutase; Thromboxane B2; Tribulus | 2011 |
Neuroprotective effect of ginkgolide K against acute ischemic stroke on middle cerebral ischemia occlusion in rats.
Topics: Animals; Antioxidants; Brain; Brain Edema; Brain Ischemia; Disease Models, Animal; Ginkgolides; Infarction, Middle Cerebral Artery; Lactones; Male; Malondialdehyde; Neuroprotective Agents; Nitric Oxide; Nitric Oxide Synthase; Oxidative Stress; Rats; Rats, Sprague-Dawley; Stroke; Superoxide Dismutase | 2012 |
Therapeutic time window for treatment of focal cerebral ischemia reperfusion injury with XQ-1h in rats.
Topics: Animals; Brain Edema; Cerebrovascular Circulation; Drug Administration Schedule; Ginkgolides; Infarction, Middle Cerebral Artery; Lactones; Male; Malondialdehyde; Rats; Rats, Wistar; Reperfusion Injury; Sodium-Potassium-Exchanging ATPase; Superoxide Dismutase | 2011 |
Rapamycin protects against middle cerebral artery occlusion induced focal cerebral ischemia in rats.
Topics: Animals; Brain; Brain Ischemia; Diffusion Magnetic Resonance Imaging; Disease Models, Animal; Dose-Response Relationship, Drug; Glutathione; Hand Strength; Humans; Infarction, Middle Cerebral Artery; Male; Malondialdehyde; Neuroimaging; Neuroprotective Agents; Nitric Oxide; Oxidative Stress; Peroxidase; Rats; Rats, Wistar; Rotarod Performance Test; Sirolimus | 2011 |
Endothelin B receptor agonist, IRL-1620, reduces neurological damage following permanent middle cerebral artery occlusion in rats.
Topics: Analysis of Variance; Animals; Brain Infarction; Disease Models, Animal; Dose-Response Relationship, Drug; Endothelin B Receptor Antagonists; Endothelins; Gene Expression Regulation; Glutathione; Infarction, Middle Cerebral Artery; Male; Malondialdehyde; Motor Activity; Muscle Strength; Nervous System Diseases; Neurologic Examination; Oligopeptides; Peptide Fragments; Piperidines; Psychomotor Performance; Rats; Rats, Sprague-Dawley; Receptor, Endothelin B; Rotarod Performance Test; Superoxide Dismutase | 2011 |
Inhibition of sevoflurane postconditioning against cerebral ischemia reperfusion-induced oxidative injury in rats.
Topics: Animals; Brain; Glutathione; Infarction, Middle Cerebral Artery; Inflammation Mediators; Interleukin-10; Interleukin-1beta; Ischemic Postconditioning; Lipids; Male; Malondialdehyde; Methyl Ethers; Neuroprotective Agents; Nitric Oxide; Oxidative Stress; Oxidoreductases; Random Allocation; Rats; Rats, Wistar; Reperfusion Injury; Sevoflurane; Tumor Necrosis Factor-alpha | 2011 |
Neuroprotective effects of NKN on focal cerebral ischemia in rats.
Topics: Abietanes; Acetophenones; Animals; Benzoates; Brain Ischemia; Bridged-Ring Compounds; Drug Combinations; Endothelin-1; Glucosides; Immunohistochemistry; In Situ Hybridization; Infarction, Middle Cerebral Artery; Male; Malondialdehyde; Neurologic Examination; Neurons; Neuroprotective Agents; Pyrazines; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Stroke; Superoxide Dismutase | 2012 |
Neuroprotective effects of pre-treatment with l-carnitine and acetyl-L-carnitine on ischemic injury in vivo and in vitro.
Topics: Acetylcarnitine; Animals; Apoptosis; Brain Ischemia; Carnitine; Infarction, Middle Cerebral Artery; Male; Malondialdehyde; Neuroprotective Agents; Oxygen; PC12 Cells; Rats; Rats, Sprague-Dawley; Superoxide Dismutase | 2012 |
Neuroimaging, biochemical and cellular evidence of protection by mycophenolate mofetil on middle cerebral artery occlusion induced injury in rats.
Topics: Animals; Glutathione; Hand Strength; Infarction, Middle Cerebral Artery; Magnetic Resonance Imaging; Male; Malondialdehyde; Mycophenolic Acid; Neuroimaging; Neuroprotective Agents; Oxidative Stress; Peroxidase; Rats; Rats, Wistar; Reperfusion Injury; Rotarod Performance Test | 2012 |
Protective effect of luteolin in experimental ischemic stroke: upregulated SOD1, CAT, Bcl-2 and claudin-5, down-regulated MDA and Bax expression.
Topics: Animals; Antioxidants; bcl-2-Associated X Protein; Blotting, Western; Body Water; Brain Chemistry; Brain Ischemia; Catalase; Claudin-5; Down-Regulation; Immunohistochemistry; Infarction, Middle Cerebral Artery; Luteolin; Male; Malondialdehyde; Neuroprotective Agents; Proto-Oncogene Proteins c-bcl-2; Rats; Rats, Sprague-Dawley; Real-Time Polymerase Chain Reaction; Stroke; Superoxide Dismutase; Superoxide Dismutase-1; Up-Regulation | 2012 |
Onion (Allium cepa) extract attenuates brain edema.
Topics: Animals; Antioxidants; Blood-Brain Barrier; Brain Edema; Disease Models, Animal; Infarction, Middle Cerebral Artery; Male; Malondialdehyde; Mice; Mice, Inbred ICR; Occludin; Onions; Phytotherapy; Plant Extracts; Reperfusion Injury; Zonula Occludens-1 Protein | 2013 |
Protective effects of MCI-186 on transplantation of bone marrow stromal cells in rat ischemic stroke model.
Topics: Analysis of Variance; Animals; Animals, Newborn; Antipyrine; Brain; Brain Infarction; Brain-Derived Neurotrophic Factor; Cell Survival; Cells, Cultured; Disease Models, Animal; Edaravone; Flow Cytometry; Free Radical Scavengers; Glucose; Hypoxia; Infarction, Middle Cerebral Artery; Magnetic Resonance Imaging; Male; Malondialdehyde; Mesenchymal Stem Cell Transplantation; Mesenchymal Stem Cells; Neurologic Examination; Neurons; Phosphopyruvate Hydratase; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Superoxide Dismutase; Time Factors; Vascular Endothelial Growth Factor A | 2012 |
N(1)-(quinolin-2-ylmethyl)butane-1,4-diamine, a polyamine analogue, attenuated injury in in vitro and in vivo models of cerebral ischemia.
Topics: Animals; Brain Ischemia; Calcium; Cells, Cultured; Cerebral Cortex; Coloring Agents; Glucose; Glutathione Peroxidase; Hypoxia; Infarction, Middle Cerebral Artery; Lipid Peroxidation; Malondialdehyde; Membrane Potential, Mitochondrial; Neurons; Neuroprotective Agents; Nitric Oxide; PC12 Cells; Polyamines; Quinolines; Rats; Reactive Oxygen Species; Tetrazolium Salts; Thiazoles | 2012 |
Coexistence of hyperlipidemia and acute cerebral ischemia/reperfusion induces severe liver damage in a rat model.
Topics: Acute Disease; Alanine Transaminase; Animals; Apoptosis; Aspartate Aminotransferases; Biomarkers; Blotting, Western; Brain; Calcium; Caspase 3; Cytochrome P-450 CYP2E1; Diet, High-Fat; Disease Models, Animal; Glutathione Peroxidase; Hyperlipidemias; Immunohistochemistry; In Situ Nick-End Labeling; Infarction, Middle Cerebral Artery; Interleukin-1; Liver; Liver Diseases; Male; Malondialdehyde; Proto-Oncogene Proteins c-bcl-2; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Superoxide Dismutase; Time Factors; Tumor Necrosis Factor-alpha | 2012 |
Effect of Sevoflurane postconditioning on gene expression in brain tissue of the middle cerebral artery occlusion rat model.
Topics: Animals; bcl-2-Associated X Protein; Brain; Brain Ischemia; Caspase 3; Catalase; Disease Models, Animal; Gene Expression Regulation; Infarction, Middle Cerebral Artery; Interleukin-1beta; Ischemic Postconditioning; Male; Malondialdehyde; Methyl Ethers; Nitric Oxide; Proto-Oncogene Proteins c-fos; Rats; Rats, Wistar; RNA, Messenger; Sevoflurane; Superoxide Dismutase; Tumor Necrosis Factor-alpha | 2012 |
Neuroprotective effect of calycosin on cerebral ischemia and reperfusion injury in rats.
Topics: Aldehydes; Animals; Behavior, Animal; Brain; Catalase; Diagnostic Techniques, Neurological; Disease Models, Animal; Glutathione Peroxidase; Infarction, Middle Cerebral Artery; Isoflavones; Male; Malondialdehyde; Mitochondria; Movement; Neuroprotective Agents; Phytotherapy; Protein Carbonylation; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Reperfusion Injury; Superoxide Dismutase | 2012 |
[The effect and mechanism of Yiqi Tongluo Jiedu capsule against cerebral ischemia reperfusion injury].
Topics: Animals; bcl-2-Associated X Protein; Brain; Capsules; Drugs, Chinese Herbal; Infarction, Middle Cerebral Artery; Interleukin-1beta; Interleukin-6; Male; Malondialdehyde; Nitric Oxide; Nitric Oxide Synthase; Plants, Medicinal; Proto-Oncogene Proteins c-bcl-2; Random Allocation; Rats; Rats, Sprague-Dawley; Reperfusion Injury; RNA, Messenger; Superoxide Dismutase; Tumor Necrosis Factor-alpha | 2012 |
[Protective effects of 1-(2,6-dimethylphenoxy)-2-(3,4-dimethoxyphenylethylamino) propane hydrochloride(DDPH) on brain ischemia injury in rats].
Topics: Animals; Brain; Brain Ischemia; Female; Infarction, Middle Cerebral Artery; Male; Malondialdehyde; Neuroprotective Agents; Phenethylamines; Rats; Rats, Wistar; Reperfusion Injury; Superoxide Dismutase | 2003 |
Protective effect of exogenous administration of alpha-tocopherol in middle cerebral artery occlusion model of cerebral ischemia in rats.
Topics: Administration, Oral; alpha-Tocopherol; Animals; Antioxidants; Behavior, Animal; Body Weight; Brain; Brain Ischemia; Disease Models, Animal; Dose-Response Relationship, Drug; Hand Strength; Infarction, Middle Cerebral Artery; Male; Malondialdehyde; Motor Activity; Rats; Rats, Wistar; Reperfusion Injury; Rotarod Performance Test | 2003 |
alpha-Phenyl-n-tert-butyl-nitrone attenuates hypoxic-ischemic white matter injury in the neonatal rat brain.
Topics: Age Factors; Aldehydes; Amyloid beta-Peptides; Analysis of Variance; Animals; Animals, Newborn; Antigens, Differentiation; Brain; Cell Count; Cell Survival; Cyclic N-Oxides; Free Radical Scavengers; Hypoxia-Ischemia, Brain; Immunohistochemistry; Infarction, Middle Cerebral Artery; Malondialdehyde; Myelin Basic Protein; Nitrogen Oxides; Oligodendroglia; Rats; Staining and Labeling; Time Factors | 2004 |
Protective effects of green tea catechins on cerebral ischemic damage.
Topics: Animals; Brain Ischemia; Catechin; Chromatography, High Pressure Liquid; Dose-Response Relationship, Drug; Granulocyte Colony-Stimulating Factor; Hematopoietic Cell Growth Factors; Infarction, Middle Cerebral Artery; Interleukin-3; Male; Malondialdehyde; Nitrates; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitrites; Plant Extracts; Rats; Rats, Wistar; Recombinant Fusion Proteins; Recombinant Proteins; Tea; Tyrosine | 2004 |
Astragaloside IV protects against ischemic brain injury in a murine model of transient focal ischemia.
Topics: Animals; Brain Chemistry; Brain Ischemia; Cardiotonic Agents; Catalase; Cerebral Infarction; Disease Models, Animal; Dose-Response Relationship, Drug; Drugs, Chinese Herbal; Glutathione Peroxidase; Infarction, Middle Cerebral Artery; Lipid Peroxidation; Male; Malondialdehyde; Mice; Mice, Inbred C57BL; Reperfusion Injury; Saponins; Superoxide Dismutase; Triterpenes | 2004 |
Neuroprotective effect of 20(S)-ginsenoside Rg3 on cerebral ischemia in rats.
Topics: Adenosine Triphosphate; Analysis of Variance; Animals; Brain Chemistry; Brain Ischemia; Calcium Channel Blockers; Cerebral Infarction; Disease Models, Animal; Dose-Response Relationship, Drug; Ginsenosides; Glutathione Peroxidase; Infarction, Middle Cerebral Artery; Male; Malondialdehyde; Mitochondria; Neurologic Examination; Neuroprotective Agents; Nimodipine; Rats; Rats, Inbred WKY; Superoxide Dismutase; Time Factors | 2005 |
Effect of endothelin antagonist (TAK-044) on cerebral ischemic volume, oxidative stress markers and neurobehavioral parameters in the middle cerebral artery occlusion model of stroke in rats.
Topics: Animals; Behavior, Animal; Biomarkers; Brain Ischemia; Diffusion Magnetic Resonance Imaging; Disease Models, Animal; Endothelins; Glutathione; Infarction, Middle Cerebral Artery; Male; Malondialdehyde; Motor Activity; Oxidative Stress; Peptides, Cyclic; Rats; Rats, Wistar; Superoxide Dismutase | 2005 |
Protective effects of isoliquiritigenin in transient middle cerebral artery occlusion-induced focal cerebral ischemia in rats.
Topics: Adenine Nucleotides; Animals; Antioxidants; Brain; Brain Edema; Brain Ischemia; Catalase; Chalcone; Chalcones; Disease Models, Animal; Dose-Response Relationship, Drug; Glycyrrhiza; Infarction, Middle Cerebral Artery; Male; Malondialdehyde; Plant Roots; Premedication; Rats; Reperfusion Injury; Sodium-Potassium-Exchanging ATPase; Superoxide Dismutase | 2006 |
[Protective effect of pueraria flavonoid on the cerebral ischemic reperfusion injury in rats].
Topics: Animals; Brain; Female; Flavonoids; Infarction, Middle Cerebral Artery; Male; Malondialdehyde; Neuroprotective Agents; Plants, Medicinal; Pueraria; Random Allocation; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Superoxide Dismutase | 2006 |
[Effects of xuezhikang and simvastatin on cerebral ischemia-reperfusion injury in rat].
Topics: Animals; Brain; Brain Ischemia; Drugs, Chinese Herbal; Infarction, Middle Cerebral Artery; Male; Malondialdehyde; Neuroprotective Agents; NG-Nitroarginine Methyl Ester; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Simvastatin | 2006 |
Neuroprotective effects of 6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid (Trolox), an antioxidant in middle cerebral artery occlusion induced focal cerebral ischemia in rats.
Topics: Animals; Brain Ischemia; Chromans; Disease Models, Animal; DNA Fragmentation; Dose-Response Relationship, Drug; Functional Laterality; In Situ Nick-End Labeling; Infarction, Middle Cerebral Artery; Lipid Peroxidation; Male; Malondialdehyde; Neuroprotective Agents; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Time Factors | 2007 |
[Effect of cyclovirobuxinum-D on cerebral ischemia-reperfusion injury in rats].
Topics: Animals; Brain; Buxus; Calcium; Drugs, Chinese Herbal; Infarction, Middle Cerebral Artery; Male; Malondialdehyde; Neuroprotective Agents; Plants, Medicinal; Random Allocation; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Superoxide Dismutase | 2007 |
Resveratrol neuroprotective effects during focal cerebral ischemia injury via nitric oxide mechanism in rats.
Topics: Animals; Brain; Brain Ischemia; Carotid Arteries; Disease Models, Animal; Dose-Response Relationship, Drug; Enzyme Inhibitors; Infarction, Middle Cerebral Artery; L-Lactate Dehydrogenase; Ligation; Male; Malondialdehyde; Middle Cerebral Artery; Neuroprotective Agents; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Ornithine; Rats; Rats, Long-Evans; Resveratrol; RNA, Messenger; Stilbenes; Up-Regulation | 2007 |
Effect of combination of endothelin receptor antagonist (TAK-044) and aspirin in middle cerebral artery occlusion model of acute ischemic stroke in rats.
Topics: Animals; Antioxidants; Aspirin; Brain Ischemia; Disease Models, Animal; Drug Therapy, Combination; Endothelin Receptor Antagonists; Glutathione; Infarction, Middle Cerebral Artery; Male; Malondialdehyde; Motor Activity; Neuroprotective Agents; Oxidative Stress; Peptides, Cyclic; Rats; Rats, Wistar; Receptors, Endothelin; Stroke; Superoxide Dismutase | 2007 |
Detrimental effects of post-treatment with fatty acids on brain injury in ischemic rats.
Topics: Animals; Apoptosis; Arachidonic Acid; Behavior, Animal; Blood-Brain Barrier; Brain; Brain Edema; Capillary Permeability; Carotid Artery, Common; Caspase 3; Cyclooxygenase 2; Disease Models, Animal; Docosahexaenoic Acids; Dose-Response Relationship, Drug; Encephalitis; Glutathione; Infarction, Middle Cerebral Artery; Injections, Intraperitoneal; Ligation; Male; Malondialdehyde; Matrix Metalloproteinases; Middle Cerebral Artery; Motor Activity; Oxidative Stress; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Reperfusion Injury; Stearic Acids; Time Factors | 2007 |
Curcuma oil: reduces early accumulation of oxidative product and is anti-apoptogenic in transient focal ischemia in rat brain.
Topics: Animals; Antioxidants; Apoptosis; Behavior, Animal; Caspase 3; Catalase; Curcuma; Glutathione Peroxidase; Infarction, Middle Cerebral Artery; Ischemic Attack, Transient; Male; Malondialdehyde; Medicine, Ayurvedic; Motor Activity; Neurons; Neuropsychological Tests; Oxidation-Reduction; Oxidative Stress; Plant Oils; Rats; Rats, Sprague-Dawley; Superoxide Dismutase | 2008 |
In vitro and in vivo neuroprotective effect and mechanisms of glabridin, a major active isoflavan from Glycyrrhiza glabra (licorice).
Topics: Animals; Apoptosis; Blotting, Western; Brain; Cell Survival; Disease Models, Animal; Glutathione; Glycyrrhiza; In Situ Nick-End Labeling; In Vitro Techniques; Infarction, Middle Cerebral Artery; Isoflavones; Male; Malondialdehyde; Neurons; Neuroprotective Agents; Phenols; Rats; Rats, Sprague-Dawley; Stroke; Superoxide Dismutase | 2008 |
Caffeic acid phenethyl ester protects rabbit brains against permanent focal ischemia by antioxidant action: a biochemical and planimetric study.
Topics: Animals; Antioxidants; Biomarkers; Brain Infarction; Brain Ischemia; Brain Mapping; Caffeic Acids; Catalase; Enzyme Inhibitors; Glutathione; Image Processing, Computer-Assisted; Infarction, Middle Cerebral Artery; Injections, Intraperitoneal; Lipid Peroxidation; Male; Malondialdehyde; Nerve Degeneration; Neuroprotective Agents; Nitric Oxide; Oxidative Stress; Phenylethyl Alcohol; Rabbits; Spectrophotometry; Treatment Outcome; Xanthine Oxidase | 2008 |
Hyperbaric oxygen preconditioning induces tolerance against brain ischemia-reperfusion injury by upregulation of antioxidant enzymes in rats.
Topics: Animals; Antioxidants; Brain; Brain Ischemia; Catalase; Enzyme Activation; Enzymes; Glutathione; Hyperbaric Oxygenation; Infarction, Middle Cerebral Artery; Ischemic Preconditioning; Male; Malondialdehyde; Oxidative Stress; Oxygen; Oxygen Consumption; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Reperfusion Injury; Superoxide Dismutase; Superoxide Dismutase-1; Up-Regulation | 2008 |
Biochemical evidence of crossed cerebellar diaschisis in terms of nitric oxide indicators and lipid peroxidation products in rats during focal cerebral ischemia.
Topics: Afferent Pathways; Animals; Cerebellum; Cerebral Cortex; Cyclic GMP; Dominance, Cerebral; Infarction, Middle Cerebral Artery; Lipid Peroxidation; Male; Malondialdehyde; Nitric Oxide; Nitrites; Pons; Rats | 2001 |
The effects of the pre-treatment of intravenous nimodipine on Na(+)-K+/Mg+2 ATPase, Ca+2/Mg+2 ATPase, lipid peroxidation and early ultrastructural findings following middle cerebral artery occlusion in the rat.
Topics: Animals; Brain Ischemia; Ca(2+) Mg(2+)-ATPase; Cerebral Cortex; Energy Metabolism; Infarction, Middle Cerebral Artery; Injections, Intravenous; Lipid Peroxidation; Male; Malondialdehyde; Neurons; Nimodipine; Rats; Rats, Wistar; Sodium-Potassium-Exchanging ATPase | 2001 |
Effects of blockade of cerebral lymphatic drainage on cerebral ischemia after middle cerebral artery occlusion in rats.
Topics: Animals; Body Water; Brain Chemistry; Brain Ischemia; Calcium; Constriction; Female; Free Radicals; Infarction, Middle Cerebral Artery; Lymphatic System; Male; Malondialdehyde; Nerve Tissue Proteins; Neurons; Oxidative Stress; Rats; Rats, Wistar; Reactive Oxygen Species; Sodium; Superoxide Dismutase | 2000 |
Antagonistic effect of 3,6-dimethamidodibenzopyriodonium gluconate on lipid peroxidation in cerebral cortical neuronal cultures and rat brains during focal cerebral ischemia reperfusion.
Topics: Animals; Antioxidants; Brain; Brain Edema; Brain Ischemia; Cells, Cultured; Cerebral Cortex; Female; Gluconates; Infarction, Middle Cerebral Artery; L-Lactate Dehydrogenase; Lipid Peroxidation; Male; Malondialdehyde; Neurons; Neuroprotective Agents; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Superoxide Dismutase | 2000 |
Effect of melatonin on ischemia reperfusion injury induced by middle cerebral artery occlusion in rats.
Topics: Animals; Antioxidants; Brain; Brain Ischemia; Glutathione; Infarction, Middle Cerebral Artery; Injections, Intraperitoneal; Magnetic Resonance Imaging; Male; Malondialdehyde; Melatonin; Rats; Rats, Wistar; Reperfusion Injury; Survival Rate; Time Factors | 2001 |
Enhanced protection by melatonin and meloxicam combination in a middle cerebral artery occlusion model of acute ischemic stroke in rat.
Topics: Animals; Antioxidants; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Drug Therapy, Combination; Infarction, Middle Cerebral Artery; Isoenzymes; Male; Malondialdehyde; Melatonin; Meloxicam; Motor Activity; Neuroprotective Agents; Prostaglandin-Endoperoxide Synthases; Rats; Rats, Wistar; Thiazines; Thiazoles | 2002 |