malondialdehyde has been researched along with Cognitive Decline in 63 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 41 (65.08) | 24.3611 |
| 2020's | 22 (34.92) | 2.80 |
| Authors | Studies |
|---|---|
| Li, G; Liu, B; Wei, J; Zhou, J | 1 |
| Liu, Y; Niu, X; Zhang, J; Zhang, Y | 1 |
| Go, MJ; Heo, HJ; Joo, SG; Kang, JY; Kim, DO; Kim, JM; Kim, MJ; Kim, TY; Lee, CJ; Lee, HR; Park, SK | 1 |
| Chen, T; Chen, Y; Li, Y; Shen, X; Tao, L; Xu, Y; Yang, H; Zhang, E | 1 |
| Cádiz-Gurrea, ML; Elmotayam, AK; Fernández-Ochoa, Á; Leyva-Jiménez, FJ; Nadeem, RI; Saber, FR; Saeed, MM; Sayed, RH; Segura-Carretero, A | 1 |
| Kostina, OV; Mazo, GE; Piatoikina, AS; Shcherbatyuk, TG; Zhilyaeva, TV; Zhukova, ES | 1 |
| Chen, N; Chen, S; Sun, Y; Wei, C; Xiu, M; Zhang, X | 1 |
| Jin, H; Li, Y; Ma, L; Sha, G; Wang, R; Zhang, Y | 1 |
| Liu, X; Liu, Y; Liu, Z; Pan, J; Ren, B; Wang, L; Yuan, T; Zhang, X; Zhao, B; Zhao, W | 1 |
| Magaji, MG; Mahmud, B; Shehu, A | 1 |
| Chen, DC; Chen, S; Curbo, ME; Li, Z; Tan, SP; Tong, YS; Wu, HE; Xiu, MH; Zhang, XY | 1 |
| Dun, XP; Gao, WL; Jing, XK; Li, XH; Li, YK; Yang, K | 1 |
| Mahmoudi, J; Majdi, A; Rahigh Aghsan, S; Sadigh-Eteghad, S; Vatandoust, SM | 1 |
| Alizadeh, A; Beheshti, F; Ghanbarabadi, M; Heydari, P; Hosseini, M; Hosseinzadeh, M; Kafami, M; Marefati, N | 1 |
| Cui, E; Li, M; Sun, J; Yan, M; Zhang, H; Zhang, Y; Zhou, J; Zhu, X | 1 |
| Albazal, A; Delshad, AA; Roghani, M | 1 |
| Li, D; Li, K; Wang, J; Wang, Q; Wang, Y; Xie, S; Zhao, J; Zuo, Z | 1 |
| Agarwal, A; Arora, R; Ganeshan N, S; Gupta, YK; Kaleekal, T; Kumar, R; Sarangi, SC | 1 |
| Jiang, Y; Ling, Y; Zhang, Y; Zhou, C; Zhou, X | 1 |
| Hao, Y; Huang, P; Lin, D; Luo, T; Shen, W; Shi, R; Wei, C; Wu, A | 1 |
| Chulikhit, Y; Daodee, S; Khamphukdee, C; Matsumoto, K; Monthakantirat, O; Noguchi, H; Putalun, W; Sukhano, W; Umehara, K; Wongpradit, R | 1 |
| Hou, J; Li, Z; Ma, X; Qin, G; Ren, G; Song, M; Wang, W; Yan, Y | 1 |
| Ha, JS; Heo, HJ; Kang, JY; Kim, DO; Kim, JM; Lee, DS; Lee, U; Park, CH; Park, SK; Seung, TW | 1 |
| Meramat, A; Rajab, NF; Shahar, S; Sharif, RA | 1 |
| Abbasalizad Farhangi, M; Hajiluian, G; Megari-Abbasi, M; Nameni, G; Shahabi, P | 1 |
| Lohidasan, S; Mahadik, KR; Nanaware, S; Shelar, M; Sinnathambi, A | 1 |
| Balmuș, IM; Ciobica, A; Dobrin, R; Nicoara, MN; Plavan, G; Ștefănescu, C; Strungaru, SA | 1 |
| Chen, H; He, J; Liu, Y; Liu, Z; Qiu, H; Shen, H; Tu, X | 1 |
| Dai, Z; Shi, H; Wang, L; Wu, P; Zhao, S | 1 |
| Chang, YL; Chang, YY; Chen, YC; Chiang, CC; Chou, CH; Lin, YL; Tu, DG | 1 |
| Baluchnejadmojarad, T; Roghani, M; Zeinali, H | 1 |
| Huang, YJ; Ke, B; Qin, J; Shi, LY; Wang, YY; Yang, YB; Zhang, L; Zhang, TY | 1 |
| Liu, H; Liu, P; Liu, X; Liu, Z; Ren, B; Tan, X; Wang, J; Zhao, B | 1 |
| Jang, CG; Kim, SY; Ko, YH; Lee, SY | 1 |
| Ayijiang, J; Chen, LN; Gong, X; Li, YN; Liu, X; Xing, T; Yan, WH; Yang, YX; Yu, Y; Zhang, CX; Zhang, M | 1 |
| Chattipakorn, N; Chattipakorn, SC; Jaiwongkam, T; Jiang, C; Kerdphoo, S; Li, X; Liang, G; Pratchayasakul, W; Sa-Nguanmoo, P; Tanajak, P; Wang, X | 1 |
| Bi, Y; Chen, J; Chen, L; Xu, L; Zhang, Q | 1 |
| Ren, N; Tian, Z; Wang, J; Zhang, D; Zhou, Y | 1 |
| Abdul Sani, NF; Abu Bakar, ZH; Ahmad Damanhuri, MH; Amir Hamzah, AIZ; Makpol, S; Mazlan, M; Mohd Rani, MD; Mohd Yusof, YA; Noh, NA; Nor Aripin, KN; Razali, R; Shamaan, NA; Tan, JK; Wan Ngah, WZ | 1 |
| Kumar, A; Mishra, VN; Singh, A; Singh, S; Verma, A | 1 |
| Cao, JB; Fu, Q; Huo, XL; Li, Y; Li, YF; Mi, WD; Wang, W; Xu, ZP; Zhang, LM; Zhang, XY; Zhao, WX | 1 |
| Cheng, XJ; Guo, AL; Li, XR; Liu, J; Liu, Y; Pang, YP; Xu, T; Yang, X; Zhang, YY | 1 |
| Cheng, YD; Lan, WC; Lee, SC; Lin, LW; Tsai, FH; Wu, CR | 1 |
| Girdhar, A; Kamboj, A; Lather, V; Pandita, D; Raheja, S | 1 |
| Cui, Y; Gao, T; Hou, C; Liu, H; Wang, A; Wang, Y; Yu, J; Zeng, Q; Zhang, B; Zhang, Z; Zhao, L | 1 |
| Farbood, Y; Ghaderi, S; Khorsandi, L; Khoshnam, SE; Rashno, M; Sarkaki, A | 1 |
| Apaijai, N; Arinno, A; Chattipakorn, N; Chattipakorn, SC; Chunchai, T; Keawtep, P; Pratchayasakul, W; Prus, D; Saiyasit, N | 1 |
| Chu, J; Deng, X; Fu, Q; Ma, S; Ma, Z; Wei, W; Xu, B; Zhu, L | 1 |
| Chen, S; He, Y; Hu, C; Li, C; Ma, Q; Wang, H; Wang, R | 1 |
| Gu, H; Guo, H; Hao, K; Jiang, W; Su, D; Xu, H | 1 |
| Barekatain, M; Djalali, M; Djazayery, A; Elmadfa, I; Feizi, A; Ghazvini, MR; Naeini, AM | 1 |
| Ingkaninan, K; Muchimapura, S; Thukham-Mee, W; Wattanathorn, J; Wittaya-Areekul, S | 1 |
| Borghi, R; Cammarata, S; Monacelli, F; Nencioni, A; Odetti, P; Piccini, A; Tabaton, M | 1 |
| Apolinário, D; Busse, AL; Cozzolino, SM; da Silva Bandeira, V; Jacob-Filho, W; Magaldi, RM; Rita Cardoso, B | 1 |
| Che, R; Dong, L; Liu, J; Ma, W; Wang, W; Xiao, R; Yuan, L | 1 |
| Ahmadvand, H; Alirezaei, M; Delfan, B; Karami, M; Khanipour, Z; Moghaddasi, M; Pourkhodadad, S | 1 |
| Cao, J; Liu, N; Ma, L; Wang, P; Wang, Y; Zhang, H; Zhou, X | 1 |
| Chen, W; Chen, Y; Li, X; Shao, S; Tang, Q; Xu, X | 1 |
| Gupta, YK; Prabhakar, P; Reeta, Kh | 1 |
| Long, H; Ma, C | 1 |
| Abdel-Rahman, MS; Abdel-Wahab, BA; Abdel-Zaher, AO; Farghaly, HSM; Farrag, MMY | 1 |
| Barros, SB; Bottino, CM; Camarini, R; Dati, LM; de Souza, GT; de Souza-Talarico, JN; Garcia, RT; Loureiro, AP; Marcourakis, T; Moreira, WL; Nitrini, R; Porto, CS; Quaglio, NB; Smid, J; Torres, LL | 1 |
| Alom, J; De Blas, I; Llinares, I; López, N; Tormo, C | 1 |
2 trial(s) available for malondialdehyde and Cognitive Decline
| Article | Year |
|---|---|
The effect of antioxidant vitamins E and C on cognitive performance of the elderly with mild cognitive impairment in Isfahan, Iran: a double-blind, randomized, placebo-controlled trial.
Topics: 8-Hydroxy-2'-Deoxyguanosine; Aged; Antioxidants; Ascorbic Acid; Cognition; Cognitive Dysfunction; Deoxyguanosine; Dietary Supplements; Double-Blind Method; Female; Glutathione; Humans; Iran; Male; Malondialdehyde; Middle Aged; Oxidative Stress; Vitamin E | 2014 |
Effects of Brazil nut consumption on selenium status and cognitive performance in older adults with mild cognitive impairment: a randomized controlled pilot trial.
Topics: Aged; Aged, 80 and over; Bertholletia; Cholesterol, HDL; Cholesterol, LDL; Cognition; Cognitive Dysfunction; Female; Glutathione Peroxidase; Humans; Male; Malondialdehyde; Nutritional Status; Nuts; Oxidative Stress; Pilot Projects; Selenium; Treatment Outcome; Triglycerides | 2016 |
61 other study(ies) available for malondialdehyde and Cognitive Decline
| Article | Year |
|---|---|
Dexmedetomidine Ameliorated Cognitive Dysfunction Induced by Intestinal Ischemia Reperfusion in Mice with Possible Relation to the Anti-inflammatory Effect Through the Locus Coeruleus Norepinephrine System.
Topics: Adrenergic Antagonists; Animals; Anti-Inflammatory Agents; Benzylamines; Cognitive Dysfunction; Dexmedetomidine; Eosine Yellowish-(YS); Hematoxylin; Ischemia; Locus Coeruleus; Malondialdehyde; Mice; Neuroprotective Agents; Neurotoxins; Norepinephrine; Reperfusion; Reperfusion Injury; Tumor Necrosis Factor-alpha; Tyrosine 3-Monooxygenase; Yohimbine | 2022 |
Naringenin Attenuates Cognitive Impairment in a Rat Model of Vascular Dementia by Inhibiting Hippocampal Oxidative Stress and Inflammatory Response and Promoting N-Methyl-D-Aspartate Receptor Signaling Pathway.
Topics: Animals; Anti-Inflammatory Agents; Aspartic Acid; Cognitive Dysfunction; Dementia, Vascular; Disease Models, Animal; Disks Large Homolog 4 Protein; Flavanones; Glutathione Peroxidase; Hippocampus; Interleukin-10; Interleukin-4; Interleukin-6; Malondialdehyde; Maze Learning; Oxidative Stress; Rats; Reactive Oxygen Species; Receptors, N-Methyl-D-Aspartate; Signal Transduction; Superoxide Dismutase; Synaptophysin; Tumor Necrosis Factor-alpha | 2022 |
Korean Red Pine (
Topics: Acetylcholine; Acetylcholinesterase; Adenosine Triphosphate; Amyloid beta-Peptides; Animals; Antioxidants; bcl-2-Associated X Protein; Brain-Derived Neurotrophic Factor; Choline O-Acetyltransferase; Cholinergic Agents; Cognitive Dysfunction; Glutathione; Malondialdehyde; Mice; Neuroinflammatory Diseases; Neuroprotective Agents; NF-KappaB Inhibitor alpha; Oxidative Stress; Pinus; Plant Bark; Plant Extracts; Reactive Oxygen Species; Republic of Korea; Superoxide Dismutase; Synaptophysin; Tumor Necrosis Factor-alpha | 2022 |
Gastrodin Ameliorates Cognitive Dysfunction in Vascular Dementia Rats by Suppressing Ferroptosis via the Regulation of the Nrf2/Keap1-GPx4 Signaling Pathway.
Topics: Animals; Benzyl Alcohols; Cognitive Dysfunction; Cyclooxygenase 2; Dementia, Vascular; Ferroptosis; Glucosides; Glutathione; Kelch-Like ECH-Associated Protein 1; Malondialdehyde; NF-E2-Related Factor 2; Oleanolic Acid; Phospholipid Hydroperoxide Glutathione Peroxidase; Rats; Signal Transduction | 2022 |
The Potential Neuroprotective Effect of
Topics: Acetylcholine; Amino Acids; Amyloid beta-Peptides; Amyloid Precursor Protein Secretases; Animals; Antioxidants; bcl-2-Associated X Protein; Cognitive Dysfunction; Cyperus; Cytokines; Esterases; Fatty Acids; Flavonoids; Malondialdehyde; Memory Disorders; Neuroprotective Agents; Plant Extracts; Rats; Scopolamine | 2022 |
Gender-related Characteristics of Oxidative Stress Severity and Cognitive Impairment in Patients With Schizophrenia.
Topics: Antioxidants; Catalase; Cognitive Dysfunction; Female; Glutathione Peroxidase; Humans; Lipid Peroxidation; Male; Malondialdehyde; Oxidative Stress; Schizophrenia; Sex Factors; Superoxide Dismutase | 2023 |
Interaction of oxidative stress and BDNF on executive dysfunction in patients with chronic schizophrenia.
Topics: Adult; Biomarkers; Brain-Derived Neurotrophic Factor; China; Cognition Disorders; Cognitive Dysfunction; Executive Function; Female; Glutathione Peroxidase; Humans; Male; Malondialdehyde; Middle Aged; Neuropsychological Tests; Oxidative Stress; Schizophrenia; Superoxide Dismutase | 2020 |
Elevated Urinary AD7c-NTP Levels in Older Adults with Hypertension and Cognitive Impairment.
Topics: Aged; Aged, 80 and over; Biomarkers; Blood Glucose; Cognition Disorders; Cognitive Dysfunction; Cross-Sectional Studies; Female; Humans; Hypertension; Insulin Resistance; Male; Malondialdehyde; Mental Status and Dementia Tests; Middle Aged; Nerve Tissue Proteins; Superoxide Dismutase-1 | 2020 |
Protective Effects of Sesamol on Systemic Inflammation and Cognitive Impairment in Aging Mice.
Topics: Aging; Amyloid beta-Peptides; Animals; Benzodioxoles; Cognitive Dysfunction; Hippocampus; Humans; Male; Malondialdehyde; Mice; Microglia; Neuroprotective Agents; Oxidative Stress; Phenols | 2020 |
Ameliorative effect of methanol stem extract of Parquetina nigrescens (Afzel) bullock on scopolamine-induced sub-chronic cognitive deficit in mice.
Topics: Acetylcholinesterase; Animals; Behavior, Animal; Brain; Cognitive Dysfunction; Dose-Response Relationship, Drug; Fabaceae; Female; Glutathione; Male; Malondialdehyde; Mice; Plant Extracts; Plant Stems; Scopolamine; Superoxide Dismutase | 2020 |
Interrelationships Between BDNF, Superoxide Dismutase, and Cognitive Impairment in Drug-Naive First-Episode Patients With Schizophrenia.
Topics: Adult; Brain-Derived Neurotrophic Factor; Cognitive Dysfunction; Female; Humans; Male; Malondialdehyde; Schizophrenia; Superoxide Dismutase; Young Adult | 2020 |
Grape Seed Proanthocyanidin Extract Ameliorates Streptozotocin-induced Cognitive and Synaptic Plasticity Deficits by Inhibiting Oxidative Stress and Preserving AKT and ERK Activities.
Topics: Alzheimer Disease; Animals; Antioxidants; Cognition; Cognitive Dysfunction; Disease Models, Animal; Glutathione; Grape Seed Extract; Hippocampus; Long-Term Potentiation; Male; Malondialdehyde; MAP Kinase Signaling System; Maze Learning; Memory; Neuronal Plasticity; Oxidative Stress; Proanthocyanidins; Proto-Oncogene Proteins c-akt; Rats; Rats, Sprague-Dawley; Streptozocin; Superoxide Dismutase | 2020 |
Cotinine ameliorates memory and learning impairment in senescent mice.
Topics: Aging; Animals; Apoptosis; Cognitive Dysfunction; Cotinine; Hippocampus; Male; Malondialdehyde; Maze Learning; Memory; Mice; Oxidative Stress; Receptors, Nicotinic; Superoxide Dismutase | 2020 |
Effect of vitamin E on cisplatin-induced memory impairment in male rats.
Topics: Animals; Antineoplastic Agents; Antioxidants; Case-Control Studies; Cisplatin; Cognitive Dysfunction; Hippocampus; Inflammation; Injections, Intraperitoneal; Lipid Peroxidation; Male; Malondialdehyde; Memory Disorders; Models, Animal; Oxidative Stress; Rats; Rats, Wistar; Spatial Memory; Superoxide Dismutase; Vitamin E | 2021 |
Dexmedetomidine attenuates sevoflurane‑induced neurocognitive impairment through α2‑adrenoceptors.
Topics: Adrenergic alpha-2 Receptor Antagonists; Animals; Caspase 3; Cognitive Dysfunction; Dexmedetomidine; Disease Models, Animal; Dose-Response Relationship, Drug; Gene Expression Regulation; Male; Malondialdehyde; Mice; Mice, Inbred C57BL; Morris Water Maze Test; Random Allocation; Sevoflurane; Superoxide Dismutase; Treatment Outcome; Yohimbine | 2021 |
Melatonin reverses cognitive deficits in streptozotocin-induced type 1 diabetes in the rat through attenuation of oxidative stress and inflammation.
Topics: Acetylcholinesterase; Animals; Antioxidants; Avoidance Learning; Cognitive Dysfunction; Diabetes Mellitus, Experimental; Hippocampus; Inflammation; Male; Malondialdehyde; Maze Learning; Melatonin; Neuroprotective Agents; Oxidative Stress; Rats; Rats, Wistar; Reactive Oxygen Species; Superoxide Dismutase | 2021 |
Enhanced anti-amnestic effect of donepezil by Ginkgo biloba extract (EGb 761) via further improvement in pro-cholinergic and antioxidative activities.
Topics: Acetylcholinesterase; Amnesia; Animals; Antioxidants; Behavior, Animal; Brain; Cell Line; Cholinergic Agents; Cognitive Dysfunction; Cyclopentanes; Disease Models, Animal; Donepezil; Drug Therapy, Combination; Furans; Ginkgo biloba; Ginkgolides; Humans; Male; Malondialdehyde; Maze Learning; Nootropic Agents; Plant Extracts; Rats, Wistar; Superoxide Dismutase | 2021 |
Pharmacodynamic and pharmacokinetic interactions of hydroalcoholic leaf extract of Centella asiatica with valproate and phenytoin in experimental models of epilepsy in rats.
Topics: Adjuvants, Pharmaceutic; Animals; Anticonvulsants; Behavior, Animal; Centella; Cognitive Dysfunction; Cytochrome P-450 Enzyme Inhibitors; Disease Models, Animal; Electroshock; Epilepsy; Glutathione; Herb-Drug Interactions; Malondialdehyde; Medicine, Ayurvedic; Methanol; Oxidative Stress; Pentylenetetrazole; Phenytoin; Plant Extracts; Plant Leaves; Rats, Wistar; Seizures; Valproic Acid | 2021 |
Poria cocos polysaccharide attenuates damage of nervus in Alzheimer's disease rat model induced by D-galactose and aluminum trichloride.
Topics: Aluminum Chloride; Alzheimer Disease; Animals; Apoptosis; Behavior, Animal; Cognition; Cognitive Dysfunction; Disease Models, Animal; Fungal Polysaccharides; Hippocampus; Malondialdehyde; Maze Learning; Neurons; Neuroprotective Agents; Oxidative Stress; Pyrrolidines; Rats; Superoxide Dismutase; Wolfiporia | 2021 |
Ginkgolide B‑mediated therapeutic effects on perioperative neurocognitive dysfunction are associated with the inhibition of iNOS‑mediated production of NO.
Topics: Animals; Apoptosis; Cognitive Dysfunction; Disease Models, Animal; Ginkgolides; Hippocampus; Lactones; Male; Malondialdehyde; Mice; Mice, Inbred C57BL; Neurocognitive Disorders; Nitric Oxide; Nitric Oxide Synthase Type II; Superoxide Dismutase; Therapeutics; Up-Regulation | 2021 |
Effects of
Topics: Animals; Cognitive Dysfunction; Cytokines; Disease Models, Animal; Estradiol; Female; Gene Expression Regulation; Hippocampus; Malondialdehyde; Maze Learning; Mice; Ovariectomy; Oxidative Stress; Phytoestrogens; Pueraria | 2021 |
Albiflorin alleviates cognitive dysfunction in STZ-induced rats.
Topics: Animals; Bridged-Ring Compounds; Cognitive Dysfunction; Diabetes Mellitus, Experimental; Hippocampus; HMGB1 Protein; Male; Malondialdehyde; Maze Learning; NF-kappa B; Oxidative Stress; Plaque, Amyloid; Rats; Rats, Wistar; Signal Transduction; Streptozocin | 2021 |
Ginsenoside Re Ameliorates Brain Insulin Resistance and Cognitive Dysfunction in High Fat Diet-Induced C57BL/6 Mice.
Topics: Animals; Brain; Cholesterol; Cognitive Dysfunction; Diabetes Mellitus, Experimental; Ginsenosides; Humans; Insulin; Insulin Resistance; Male; Malondialdehyde; Mice; Mice, Inbred C57BL; Triglycerides | 2017 |
DNA Damage, Copper and Lead Associates with Cognitive Function among Older Adults.
Topics: Aged; Biomarkers; Cognition; Cognition Disorders; Cognitive Dysfunction; Comet Assay; Copper; Cross-Sectional Studies; DNA Damage; Female; Humans; Lead; Logistic Models; Malaysia; Male; Malondialdehyde; Middle Aged; Nails; Odds Ratio; Oxidative Stress; Risk Factors; Superoxide Dismutase; Trace Elements | 2017 |
Oxidative stress-induced cognitive impairment in obesity can be reversed by vitamin D administration in rats.
Topics: Animals; Biomarkers; Catalase; Cognitive Dysfunction; Diet, High-Fat; Glutathione Peroxidase; Hippocampus; Male; Malondialdehyde; NF-kappa B; Obesity; Oxidative Stress; Rats; Rats, Wistar; Superoxide Dismutase; Thiobarbituric Acid Reactive Substances; Tumor Necrosis Factor-alpha; Vitamin D | 2018 |
Neuroprotective effect of Indian propolis in β-amyloid induced memory deficit: Impact on behavioral and biochemical parameters in rats.
Topics: Acetylcholinesterase; Alzheimer Disease; Amyloid beta-Peptides; Animals; Antioxidants; Brain; Cholinesterase Inhibitors; Cognitive Dysfunction; Male; Malondialdehyde; Maze Learning; Memory; Memory Disorders; Neuroprotective Agents; Oxidative Stress; Plant Extracts; Propolis; Rats; Rats, Wistar | 2017 |
Preliminary Data on the Interaction between Some Biometals and Oxidative Stress Status in Mild Cognitive Impairment and Alzheimer's Disease Patients.
Topics: Aged; Alzheimer Disease; Cognitive Dysfunction; Enzyme Assays; Female; Glutathione Peroxidase; Humans; Iron; Lipid Peroxidation; Magnesium; Male; Malondialdehyde; Manganese; Metals; Middle Aged; Oxidative Stress; Spectrophotometry, Atomic; Superoxide Dismutase | 2017 |
High Serum Levels of Malondialdehyde and 8-OHdG are both Associated with Early Cognitive Impairment in Patients with Acute Ischaemic Stroke.
Topics: 8-Hydroxy-2'-Deoxyguanosine; Aged; Biomarkers; Cognitive Dysfunction; Deoxyguanosine; Female; Humans; Male; Malondialdehyde; Middle Aged; ROC Curve; Stroke; Time Factors | 2017 |
Lack of mitochondrial ferritin aggravated neurological deficits via enhancing oxidative stress in a traumatic brain injury murine model.
Topics: Acetylcysteine; Animals; Antioxidants; Brain; Brain Injuries, Traumatic; Cognitive Dysfunction; Disease Models, Animal; Ferritins; Glutathione; Malondialdehyde; Memory Disorders; Mice; Mice, Knockout; Mitochondria; Mitochondrial Proteins; Nitric Oxide; Oxidative Stress; Superoxide Dismutase | 2017 |
Preventive effects of taurine against d-galactose-induced cognitive dysfunction and brain damage.
Topics: Animals; Brain Injuries; Cognitive Dysfunction; Galactose; Glial Fibrillary Acidic Protein; Glycation End Products, Advanced; Hippocampus; Humans; Male; Malondialdehyde; Memory; Mice; Mice, Inbred ICR; Oxidative Stress; Taurine | 2018 |
Scutellarin alleviates lipopolysaccharide-induced cognitive deficits in the rat: Insights into underlying mechanisms.
Topics: Animals; Apigenin; Cognitive Dysfunction; Glucuronates; Hippocampus; Inflammation; Interleukin-6; Lipopolysaccharides; Male; Malondialdehyde; Neuroprotective Agents; NF-kappa B; Rats; Rats, Wistar; Superoxide Dismutase; Tumor Necrosis Factor-alpha | 2018 |
Caloric restriction ameliorates acrolein-induced neurotoxicity in rats.
Topics: Acrolein; Amyloid beta-Protein Precursor; Amyloid Precursor Protein Secretases; Animals; Brain-Derived Neurotrophic Factor; Caloric Restriction; Cerebral Cortex; Cognitive Dysfunction; Glutathione; Hippocampus; Male; Malondialdehyde; Maze Learning; Neurotoxicity Syndromes; Oxidative Stress; Rats; Receptor for Advanced Glycation End Products; Receptor, trkB; Signal Transduction; Superoxide Dismutase | 2018 |
Lycopene Supplementation Attenuates Oxidative Stress, Neuroinflammation, and Cognitive Impairment in Aged CD-1 Mice.
Topics: Animals; Antioxidants; Carotenoids; Catalase; Cognitive Aging; Cognitive Dysfunction; Glutathione; Heme Oxygenase-1; Humans; Lycopene; Male; Malondialdehyde; Memory; Mice; Neurons; Oxidative Stress | 2018 |
6,7,4'-Trihydroxyisoflavone, a major metabolite of daidzein, improves learning and memory via the cholinergic system and the p-CREB/BDNF signaling pathway in mice.
Topics: Acetylcholinesterase; Animals; Avoidance Learning; Brain-Derived Neurotrophic Factor; Cholinergic Agents; Cognition; Cognitive Dysfunction; Cyclic AMP Response Element-Binding Protein; Disease Models, Animal; Hippocampus; Humans; Isoflavones; Male; Malondialdehyde; Maze Learning; Memory Disorders; Mice; Mice, Inbred ICR; Phosphorylation; Scopolamine; Signal Transduction; Thiobarbituric Acid Reactive Substances | 2018 |
[Nicorandil improves cognitive dysfunction in mice with streptozotocin-induced diabetes].
Topics: Animals; Blood Glucose; Cognitive Dysfunction; Diabetes Mellitus, Experimental; Gastric Inhibitory Polypeptide; Glucagon-Like Peptide 1; Hippocampus; Insulin-Secreting Cells; Malondialdehyde; Mice; Mice, Inbred C57BL; Nicorandil; Streptozocin; Superoxide Dismutase | 2018 |
FGF21 and DPP-4 inhibitor equally prevents cognitive decline in obese rats.
Topics: Adamantane; Animals; Apoptosis; Cognitive Dysfunction; Dipeptidyl-Peptidase IV Inhibitors; Fibroblast Growth Factors; Hippocampus; Humans; Insulin Resistance; Male; Malondialdehyde; Mitochondria; Neuronal Plasticity; Nitriles; Obesity; Oxidative Stress; Pyrrolidines; Rats, Wistar; Signal Transduction; Vildagliptin | 2018 |
Tanshinone IIA exerts neuroprotective effects on hippocampus-dependent cognitive impairments in diabetic rats by attenuating ER stress-induced apoptosis.
Topics: Abietanes; Animals; Apoptosis; Cognitive Dysfunction; Diabetes Mellitus, Experimental; Disease Models, Animal; Endoplasmic Reticulum Chaperone BiP; Endoplasmic Reticulum Stress; Heat-Shock Proteins; Hippocampus; Male; Malondialdehyde; Maze Learning; Neurons; Neuroprotective Agents; Rats; Rats, Sprague-Dawley; Streptozocin; Superoxide Dismutase; Transcription Factor CHOP | 2018 |
Ginsenoside Ameliorates Cognitive Dysfunction in Type 2 Diabetic Goto-Kakizaki Rats.
Topics: Animals; Blood Glucose; Body Weight; Cognitive Dysfunction; Cytokines; Diabetes Mellitus, Type 2; Drinking; Fasting; Feeding Behavior; Ginsenosides; Hippocampus; Inflammation Mediators; Male; Malondialdehyde; Memory; Oxidative Stress; Rats, Wistar; Superoxide Dismutase | 2018 |
DNA damage and protein oxidation associated with ageing correlate with cognitive dysfunction in a Malaysian population.
Topics: Adult; Aged; Aging; Cognitive Dysfunction; DNA Damage; Female; Humans; Male; Malondialdehyde; Middle Aged; Oxidative Stress | 2018 |
Diffusion tensor imaging based white matter changes and antioxidant enzymes status for early identification of mild cognitive impairment.
Topics: Aged; Biomarkers; Cognitive Dysfunction; Diffusion Tensor Imaging; Female; Glutathione Peroxidase; Humans; Lipid Peroxidation; Male; Malondialdehyde; Middle Aged; Superoxide Dismutase; White Matter | 2019 |
Vitamin C alleviates LPS-induced cognitive impairment in mice by suppressing neuroinflammation and oxidative stress.
Topics: Animals; Anti-Inflammatory Agents; Ascorbic Acid; Cognitive Dysfunction; Cytokines; Disease Models, Animal; Humans; Lipopolysaccharides; Male; Malondialdehyde; Maze Learning; Memory Disorders; Mice; Mice, Inbred C57BL; Neurogenic Inflammation; Oxidative Stress; p38 Mitogen-Activated Protein Kinases; Signal Transduction | 2018 |
Astaxanthin Attenuates Environmental Tobacco Smoke-Induced Cognitive Deficits: A Critical Role of p38 MAPK.
Topics: Animals; Catalase; Cerebral Cortex; Cognition; Cognitive Dysfunction; Cytokines; Glutathione; Hippocampus; Interleukin-6; Male; Malondialdehyde; Mice; NF-kappa B; Nicotiana; Oxidative Stress; p38 Mitogen-Activated Protein Kinases; Smoke; Tumor Necrosis Factor-alpha; Xanthophylls | 2019 |
Steroid-Enriched Fraction of Achyranthes bidentata Protects Amyloid β Peptide 1-40-Induced Cognitive Dysfunction and Neuroinflammation in Rats.
Topics: Acetylcholinesterase; Achyranthes; Amyloid beta-Peptides; Animals; Antioxidants; Astrocytes; Behavior, Animal; Brain; Cognitive Dysfunction; Cytokines; Ecdysterone; Glutathione; Hippocampus; Inflammation; Male; Malondialdehyde; MAP Kinase Signaling System; Maze Learning; Memory; Microglia; Neuroprotective Agents; NF-kappa B; Oleanolic Acid; Peptide Fragments; Rats, Sprague-Dawley; Steroids; Triterpenes; Ursolic Acid | 2019 |
Aegle marmelos leaf extract ameliorates the cognitive impairment and oxidative stress induced by intracerebroventricular streptozotocin in male rats.
Topics: Acetylcholinesterase; Aegle; Animals; Cognition; Cognition Disorders; Cognitive Dysfunction; Hippocampus; Injections, Intraventricular; Interleukin-6; Male; Malondialdehyde; Maze Learning; Medicine, East Asian Traditional; Memory Disorders; Neuroprotective Agents; Oxidative Stress; Plant Extracts; Plant Leaves; Rats; Rats, Wistar; Streptozocin; Tumor Necrosis Factor-alpha | 2019 |
3-Methyladenine alleviates excessive iodine-induced cognitive impairment via suppression of autophagy in rat hippocampus.
Topics: Adenine; Animals; Autophagy; Cognitive Dysfunction; Female; Hippocampus; Iodine; Male; Malondialdehyde; Maze Learning; Rats | 2019 |
Sesamin: A promising protective agent against diabetes-associated cognitive decline in rats.
Topics: Animals; Antioxidants; Apoptosis; Cognitive Dysfunction; Diabetes Complications; Diabetes Mellitus, Experimental; Dioxoles; Glutathione Peroxidase; Hippocampus; Insulin; Lignans; Male; Malondialdehyde; Oxidative Stress; Protective Agents; Rats; Rats, Wistar; Reactive Oxygen Species; Superoxide Dismutase | 2019 |
N-acetyl cysteine, inulin and the two as a combined therapy ameliorate cognitive decline in testosterone-deprived rats.
Topics: Acetylcysteine; Animals; Apoptosis; Astrocytes; Blood-Brain Barrier; Brain; Castration; Cognition; Cognitive Dysfunction; Disease Models, Animal; Drug Therapy, Combination; Dysbiosis; Hippocampus; Inflammation; Inulin; Male; Malondialdehyde; Microglia; Motor Activity; Oxidative Stress; Rats; Rats, Wistar; Reactive Oxygen Species; Testosterone | 2019 |
Esculetin improves cognitive impairments induced by transient cerebral ischaemia and reperfusion in mice via regulation of mitochondrial fragmentation and mitophagy.
Topics: Animals; Apoptosis; Autophagy; Brain Ischemia; Cognitive Dysfunction; Dynamins; Ischemic Attack, Transient; Male; Malondialdehyde; Mice; Mice, Inbred ICR; Mitochondria; Mitophagy; NF-E2-Related Factor 2; Reactive Oxygen Species; Reperfusion Injury; Superoxide Dismutase; Umbelliferones | 2019 |
Protective effect of sakuranetin in brain cells of dementia model rats.
Topics: Alzheimer Disease; Animals; Behavior, Animal; Cognitive Dysfunction; Disease Models, Animal; Flavonoids; Galactose; Glutathione Peroxidase; Hippocampus; Interleukin-6; Male; Malondialdehyde; Memory; NF-KappaB Inhibitor alpha; Oryza; Plant Extracts; Protective Agents; Rats; Rats, Wistar; Signal Transduction; Spatial Navigation; Superoxide Dismutase; Tumor Necrosis Factor-alpha | 2019 |
Ameliorative effect of Magnesium Isoglycyrrhizinate on hepatic encephalopathy by Epirubicin.
Topics: Animals; Antibiotics, Antineoplastic; Carrier Proteins; Cognitive Dysfunction; Cytokines; Epirubicin; Hepatic Encephalopathy; Hippocampus; Male; Malondialdehyde; Memory; Mice, Inbred BALB C; Neuroprotective Agents; NF-E2-Related Factor 2; NF-kappa B; Saponins; Spatial Learning; Superoxide Dismutase; Thioredoxins; Triterpenes | 2019 |
Mangifera indica fruit extract improves memory impairment, cholinergic dysfunction, and oxidative stress damage in animal model of mild cognitive impairment.
Topics: Acetylcholine; Alcohols; Animals; Biomarkers; Catalase; Cognitive Dysfunction; Disease Models, Animal; Fruit; Glutathione Peroxidase; Hippocampus; Male; Malondialdehyde; Mangifera; Maze Learning; Memory; Memory Disorders; Oxidative Stress; Phytotherapy; Plant Extracts; Rats; Rats, Wistar; Superoxide Dismutase | 2014 |
Amnestic mild cognitive impairment and conversion to Alzheimer's disease: insulin resistance and glycoxidation as early biomarker clusters.
Topics: Aged; Alzheimer Disease; Arginine; Blood Glucose; Case-Control Studies; Cognitive Dysfunction; Disease Progression; Female; Humans; Insulin; Insulin Resistance; Lysine; Male; Malondialdehyde; Neuropsychological Tests; Psychiatric Status Rating Scales; Statistics as Topic | 2015 |
Dietary pattern and antioxidants in plasma and erythrocyte in patients with mild cognitive impairment from China.
Topics: 8-Hydroxy-2'-Deoxyguanosine; Aged; alpha-Tocopherol; Alzheimer Disease; Antioxidants; Biomarkers; Body Mass Index; Body Weight; Case-Control Studies; China; Cholesterol, HDL; Cholesterol, LDL; Cognition; Cognitive Dysfunction; Deoxyguanosine; Diet; Erythrocytes; Female; Flavonoids; Humans; Life Style; Male; Malondialdehyde; Middle Aged; Nutrition Assessment; Oxidative Stress; Red Meat; Seafood; Socioeconomic Factors; Surveys and Questionnaires; Vitamin A | 2016 |
Neuroprotective effects of oleuropein against cognitive dysfunction induced by colchicine in hippocampal CA1 area in rats.
Topics: Animals; Behavior, Animal; CA1 Region, Hippocampal; Caspase 3; Catalase; Cognitive Dysfunction; Colchicine; Glutathione Peroxidase; Iridoid Glucosides; Iridoids; Lipid Peroxidation; Male; Malondialdehyde; Neuroprotective Agents; Nitric Oxide; Oxidative Stress; Rats; Rats, Wistar; Spatial Learning; Spatial Memory | 2016 |
Protective Effects of Edaravone in Adult Rats with Surgery and Lipopolysaccharide Administration-Induced Cognitive Function Impairment.
Topics: Animals; Antipyrine; Brain; Cognitive Dysfunction; Cytokines; Disease Models, Animal; Edaravone; Free Radical Scavengers; Humans; Inflammation Mediators; Lipopolysaccharides; Male; Malondialdehyde; Nephrectomy; Neuroprotective Agents; Oxidative Stress; Postoperative Complications; Proto-Oncogene Proteins c-akt; Rats; Rats, Sprague-Dawley; Superoxide Dismutase; TOR Serine-Threonine Kinases | 2016 |
Oxidative stress induces the decline of brain EPO expression in aging rats.
Topics: Aging; Animals; beta-Galactosidase; Cognitive Dysfunction; Erythropoietin; Galactose; Hippocampus; Linear Models; Male; Malondialdehyde; Maze Learning; Neuroprotective Agents; Oxidative Stress; Rats; Rats, Sprague-Dawley; Transcription Factors | 2016 |
Anticonvulsant activity of the antidepressant drug, tianeptine, against pentylenetetrazole-induced seizures mitigates cognitive impairment in rats.
Topics: Animals; Anticonvulsants; Antidepressive Agents, Tricyclic; Avoidance Learning; Behavior, Animal; Cognitive Dysfunction; Dizocilpine Maleate; Dose-Response Relationship, Drug; Glutathione; Male; Malondialdehyde; Maze Learning; Naloxone; Oxidative Stress; Pentylenetetrazole; Rats; Rats, Wistar; Seizures; Thiazepines | 2016 |
Protective effect of betulin on cognitive decline in streptozotocin (STZ)-induced diabetic rats.
Topics: Animals; Cognitive Dysfunction; Cytokines; Diabetes Mellitus, Experimental; Disease Models, Animal; Dose-Response Relationship, Drug; Glucose Tolerance Test; Heme Oxygenase-1; Hippocampus; Male; Malondialdehyde; Maze Learning; NF-E2-Related Factor 2; NF-kappa B; Rats; Rats, Sprague-Dawley; Superoxide Dismutase; Triterpenes; Up-Regulation | 2016 |
A potential mechanism for the ameliorative effect of thymoquinone on pentylenetetrazole-induced kindling and cognitive impairments in mice.
Topics: Animals; Avoidance Learning; Behavior, Animal; Benzoquinones; Brain; Cognitive Dysfunction; Glutathione; Glutathione Peroxidase; Immunohistochemistry; Isoenzymes; Kindling, Neurologic; Male; Malondialdehyde; Maze Learning; Mice; Nitric Oxide Synthase Type I; Nitrites; Pentylenetetrazole; RNA, Messenger | 2017 |
Peripheral oxidative stress biomarkers in mild cognitive impairment and Alzheimer's disease.
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Analysis of Variance; Biomarkers; Catalase; Cognitive Dysfunction; Female; Glutathione Peroxidase; Glutathione Reductase; Glutathione Transferase; Humans; Lipid Peroxidation; Male; Malondialdehyde; Mental Status Schedule; Neuropsychological Tests; Oxidative Stress | 2011 |
Oxidative stress in Alzheimer's disease and mild cognitive impairment with high sensitivity and specificity.
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Analysis of Variance; Ceruloplasmin; Cognitive Dysfunction; Copper; Female; Humans; Logistic Models; Male; Malondialdehyde; Mental Status Schedule; Oxidative Stress; ROC Curve; Sensitivity and Specificity; Superoxide Dismutase | 2013 |