malondialdehyde has been researched along with Alloxan Diabetes in 789 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (0.63) | 18.7374 |
| 1990's | 55 (6.97) | 18.2507 |
| 2000's | 172 (21.80) | 29.6817 |
| 2010's | 492 (62.36) | 24.3611 |
| 2020's | 65 (8.24) | 2.80 |
| Authors | Studies |
|---|---|
| Ahmadiasl, N; Daghigh, F; Habibi, P; Komaki, A; Sadeghian, R; Shahidi, S; Yousefi, H | 2 |
| Chen, M; Dai, Y; Liu, C; Peng, L; Wu, P; Xie, Q; Zhang, X | 1 |
| Liu, Y; Lyu, K; Ran, J; Yue, W; Zhu, X | 1 |
| Adebayo, OG; Ajayi, AM; Badaki, V; Ben-Azu, B | 1 |
| Ali, DA; Hazem, RM; Ibrahim, AZ; Moustafa, YM | 1 |
| Li, Y; Wang, X | 1 |
| Ahmad, W; Al-Harrasi, A; Csuk, R; Halim, SA; Karim, N; Khan, A; Khan, I; Khan, M; Rehman, NU | 1 |
| Aladeyelu, OS; Azu, OO; Lawal, S; Moodley, R; Naidu, ECS; Olojede, SO; Rennie, CO; Sulaiman, SO | 1 |
| Bivolarska, AV; Boyanov, KO; Choneva, MA; Delchev, SD; Dimitrov, IV; Dimov, I; Georgieva, KN; Gerginska, FD; Hrischev, PI; Vlaykova, TI | 1 |
| Hussein, RM; Salama, M; Saleh, H | 1 |
| Ali, RH; Ali, SK | 1 |
| Dogan, A; Duman, KE; Kaptaner, B | 1 |
| Abedimanesh, N; Eskandari, MR; Fathi, M; Khodabandehloo, H; Mohammadnejad, J; Mohammadnejad, K; Motlagh, B; Mousavi, M; Nikkhah, M; Sharini, E; Talebi, M | 1 |
| Cui, HY; Feng, JH; Gao, JP; Liu, XN; Wei, KZ; Xu, X; Yao, PA; Zhang, XC | 1 |
| Alizadeh, S; Kheirollahi, A; Langroudi, FE; Narani, MS; Shokrpoor, S; Vatannejad, A | 1 |
| Malik, F; Sida, NA | 1 |
| Alonso, MR; Anesini, C; Arcos, MLB; Cremaschi, G; Marrassini, C; Peralta, I | 1 |
| Hanchang, W; Khamchan, A; Seedadee, C; Wongmanee, N | 1 |
| Hsu, YC; Kong, ZL; Kuo, HP; Su, CY; Sudirman, S | 1 |
| Latiff, AA; Mardiana, AA; Sahema, ZCT; Santhana, RL; Syed Ahmad Fuad, SB; Zaidun, NH | 1 |
| Abbas, SY; Ali, SA; Aly, HF; Arafa, AF; Basyouni, WM; El-Bayouki, KAM; El-Mansy, MF; Haroun, AA; Sroor, FM | 1 |
| Jiang, YP; Liu, N; Liu, P; Ma, L; Niu, JG; Yang, JM; Ye, RJ; Yu, JQ; Zhang, WJ; Zheng, P | 1 |
| Abd El-Ghffar, EA; Barakat, A; El-Raey, MA; Hegazi, NM; Saad, HH; Shehata, SM; Sobeh, M; Soliman, MM; Yasri, A | 1 |
| Jiang, YP; Liu, N; Ma, L; Niu, JG; Sun, T; Yang, JM; Ye, RJ; Yu, JQ; Zhang, WJ; Zheng, P | 1 |
| Baluchnejadmojarad, T; Goudarzi, M; Jamali-Raeufy, N; Keimasi, S; Roghani, M | 1 |
| Ergenc, M; Ozacmak, HS; Ozacmak, VH; Turan, I | 1 |
| Sun, A; Xu, X; Yan, L | 1 |
| Duan, C; Fan, H; Liu, X; Wang, J; Wei, C | 1 |
| Anisina, EA; Durnev, AD; Gudasheva, TA; Ostrovskaya, RU; Yagubova, SS; Zhanataev, AK | 1 |
| Chen, X; Shi, F; Yuan, H; Zhu, Y | 1 |
| Eslami, P; Ghomi, H; Mirmiranpour, H; Rezaeinezhad, A | 1 |
| Akbari, A; Jelodar, G; Mohammadi, M; Nazifi, S | 1 |
| Ma, A; Wang, T; Wang, Y; Wei, X; Yang, Y; Zhou, Y | 1 |
| Abbasalipourkabir, R; Gholamhosseinian, A; Sayadi, K; Sayadi, M; Ziamajidi, N | 1 |
| Elguindy, NM; Hashem, HM; Maher, AM; Saleh, SR; Yacout, GA | 1 |
| Abdelkader, NF; Badawi, MA; Eitah, HE; Gamaleldin, AA; Kenawy, SA; Maklad, YA | 1 |
| Dirican, M; Sarandol, E; Serdar, Z; Tas, S | 1 |
| Karbalaei, N; Keshtgar, S; Nemati, M; Zarin, M | 1 |
| Agirman, E; Celik, I; Dogan, A | 1 |
| Algül, S; Belhan, S; Huyut, Z; Oto, G; Özdek, U; Yıldırım, S | 1 |
| Abdraboh, ME; Al Syaad, KM; Al-Doaiss, AA; Elsaid, FG | 1 |
| Ghiasi, R; Naderi, R; Pourheydar, B; Shafiei, F | 1 |
| Chen, G; Du, JW; Fan, XY; Feng, J; Jin, YL; Nie, Q; Zheng, XP | 1 |
| Kisacam, MA; Kocamuftuoglu, GO; Ozan, ST; Ufat, H | 1 |
| Gaikwad, AB; Sharma, N | 1 |
| Gao, M; Kang, Y; Li, H; Liu, L; Luan, X; Qu, C; Zhang, L; Zhang, S | 1 |
| Abdel Fattah, S; El-Enein, AA; Kamel, A; Labib, H; Waly, H | 1 |
| Chang, KB; He, JL; Kong, ZL; Kuo, MT; Miao, S; Sudirman, S; Tsou, D | 1 |
| Bodakhe, SH; Singh, A | 1 |
| Alabi, TD; Masola, B; Mpahleni, B; Opperman, M; Oyenihi, AB | 1 |
| Alves, CQ; David, JM; Espírito-Santo, RF; Gama, KB; Juiz, PJL; Lauria, PSS; Santos, DS; Soares, MBP; Villarreal, CF | 1 |
| Said, E; Salem, HA; Samaha, MM | 2 |
| Chu, Y; Jiang, H; Li, J; Ma, Z | 1 |
| Kulkarni, YA; Suryavanshi, SV | 1 |
| El-Shahat, MA; Elhessy, HM; Eltahry, H; Erfan, OS; Hazem, NM; Mahdi, MR | 1 |
| Ishak, NIM; Lau, S; Mohamed, S; Mustapha, NM; Nahar, N; Umran, NS | 1 |
| Imagawa, A; Jin, D; Takai, S; Terai, K; Watase, K | 1 |
| Li, J; Wang, G; Zhang, H | 1 |
| Aydın, S; Erman, O; Kaya, T; Yılmaz, Ö | 1 |
| Bevoor, DB; Bukhari, SNA; Chitti, R; Gubbiyappa, KS; Hiremath, AR; Khan, T; Li, P; Singh, Y; SreeHarsha, N | 1 |
| Azimullah, S; Bansal, N; Kilari, BP; Maqsood, S; Mudgil, P; Ojha, S | 1 |
| Chaiprasart, P; Hanchang, W; Pohsa, S; Singpoonga, N; Taepavarapruk, P | 1 |
| Albazal, A; Delshad, AA; Roghani, M | 1 |
| Ezzeldin, E; Mostafa, GAE; Nazir, N; Ullah, R; Zahoor, M | 1 |
| Ahmadi, M; Bolboli, L; Haghighi, L; Hassanpour, M; Keyhanmanesh, R; Mahdipour, M; Rahbarghazi, A; Rahbarghazi, R; Siahkouhian, M; Sokouti Nasimi, F | 1 |
| Leung, SWS; Mokhtar, SS; Rasool, AHG; Singh, KKB; Wee, CL; Yahaya, S | 1 |
| Cui, J; Guo, G; Luo, Y; Wan, H; Xie, S; Zhou, G | 1 |
| Ba, Y; Chen, Y; Gao, T; Liu, C; Niu, Q; Shi, N; Wang, H; Zhao, K | 1 |
| Erukainure, OL; Islam, MS; Olofinsan, KA; Salau, VF | 1 |
| Atkin, SL; Barreto, GE; Sahebkar, A; Yaribeygi, H | 1 |
| Ashraf, GM; Barreto, GE; Chavda, V; Patel, SS; Rajput, R | 1 |
| Abdelrahman, SA; Abdullah, DM; Hussein, S; Mohamed, DA; Youssef, AM | 1 |
| Abdel-Moneim, A; Ebeid, ASM; El-Shahawy, AAG; Eldin, ZE; Zanaty, MI | 1 |
| Diao, XH; Li, QC; Li, XF; Liu, HY; Pang, YW; Shi, ZD; Song, H; Wang, YL; Zhou, SH | 1 |
| Hou, J; Li, Z; Ma, X; Qin, G; Ren, G; Song, M; Wang, W; Yan, Y | 1 |
| Ha, JS; Heo, HJ; Kang, JY; Kim, DO; Kim, JM; Lee, DS; Lee, U; Park, CH; Park, SK; Seung, TW | 1 |
| Chen, Q; Chen, Z; Cheng, X; Ge, S; Gu, X; Mu, L; Ni, L; Sun, H; Wang, J | 1 |
| Khalili, A; Khosravi, MB; Nekooeian, AA | 1 |
| Chegou, NN; Masola, B; Oguntibeju, OO; Oyenihi, AB | 1 |
| Al Jaouni, SK; Almadaly, EA; Assar, DH; Atta, MS; El-Far, AH; Mousa, SA; Saleh, RM | 1 |
| Kan, J; Ren, T; Zhu, Y | 1 |
| Madhuri, K; Naik, PR | 1 |
| Dong, Y; Guo, Z; Huang, H; Liu, H; Wang, H; Wang, W; Xu, J; Zhou, Y | 1 |
| Lebda, MA; Nasr, SM; Sadek, KM; Shoukry, M | 1 |
| Khavarimehr, M; Najafi, G; Nejati, V; Razi, M | 1 |
| Chen, C; Fu, X; Huang, Q; Li, C | 1 |
| Karagenc, L; Sandikci, M; Yildiz, M | 1 |
| Chen, ZZ; Dou, J; Lei, SQ; Leng, Y; Meng, QT; Wu, Y; Xia, ZY; Zhao, B; Zhu, J | 1 |
| Abdel-Rahman, N; Eissa, LA; Eraky, SM | 1 |
| Gu, C; He, L; Huang, Z; Li, J; Pan, L; Sheng, M; Teng, L; Xu, C; Yi, C; Yu, M | 1 |
| Chen, L; Mao, Y; Pan, J; Wang, S; Xiang, J; Zhang, L | 1 |
| Pandir, D; Uçar, S | 1 |
| Anlar, HG; Arı, N; Aydın, S; Bacanlı, M; Başaran, AA; Başaran, N; Çal, T; Ündeğer Bucurgat, Ü | 1 |
| Meng, Q; Sha, J; Su, X; Sui, B; Zhang, C | 1 |
| Aydos, RD; da Silva, BAK; de Carvalho, PTC; de Senna Cardoso, BM; Denadai, AS; Olmedo, L; Silva, IS | 1 |
| Abbas, AM; Elserougy, HG; Safwat, SM; Samir, SM | 1 |
| Cao, H; Cheng, P; Fang, J; Jiao, R; Jin, L; Li, T; Li, Y; Li, Z; Liu, X; Ma, Y; Tang, J; Wei, X; Xing, Y | 1 |
| Chatsudthipong, V; Chattipakorn, N; Jaikumkao, K; Lungkaphin, A; Pongchaidecha, A; Thongnak, L | 1 |
| Han, W; Yu, Q; Zhai, H; Zhu, Y | 1 |
| Li, X; Shen, G; Wu, B; Wu, Q; Xie, Z | 1 |
| Jia, Q; Liu, X; Lu, H; Ma, S; Wang, Q; Yang, R | 1 |
| Asghari-Jafarabadi, M; Khorram, S; Mesgari, M; Omidi, H; Tarighat-Esfanjani, A | 1 |
| Mohammadi, MT; Sahebkar, A; Yaribeygi, H | 2 |
| Adeyonu, O; Ajiboye, BO; Fadaka, AO; Imiere, OD; Ojo, OA; Osukoya, AO | 1 |
| Chen, X; Dou, J; He, J; Lei, X; Ren, C; Zhou, Y | 1 |
| Nasanova, ON; Vengerovsky, AI; Yakimova, TV | 1 |
| Lin, N; Liu, D; Liu, X; Luo, Y; Miao, Y; Wan, Q; Wang, Y; Zhong, J; Zhou, H | 1 |
| Hong, JT; Hwang, DY; Kim, JE; Koh, EK; Lee, HA; Song, SH; Sung, JE; Yun, WB | 1 |
| Chen, H; Duan, X; Hu, B; Ke, Y; Li, C; Liu, A; Liu, Y; Shen, L; Shen, Y; Tang, T; Wu, W; Zhang, L | 1 |
| Anlar, HG; Arı, N; Aydın, S; Bacanlı, M; Başaran, AA; Başaran, AN; Çal, T; Ündeğer Bucurgat, Ü | 1 |
| Goli, F; Hashemnia, M; Karimi, J; Kheiripour, N; Khodadadi, I; Rahimi, R; Tayebinia, H | 1 |
| Fatemi, I; Ghaznavi, H; Mehrzadi, S; Motevalian, M; Rezaei Kanavi, M; Shahriari, M | 1 |
| Hafez, HM; Mohamed, MZ; Mohammed, HH; Zenhom, NM | 1 |
| Masola, B; Oguntibeju, OO; Oyenihi, AB | 1 |
| Dadras, F; Ghasemi, H; Kheiripour, N; Khoshjou, F; Ranjbar, A; Seif Rabiei, MA | 1 |
| Abdelaziz, RR; Abdelhamid, AM; Salem, HAA | 1 |
| Baltaci, AK; Baltaci, SB; Bicer, M; Mogulkoc, R; Patlar, S | 1 |
| Jin, XD; Li, HZ; Liu, JT; Meng, NN; Wen, YJ; Yuan, XH; Zhang, CL; Zhang, YF | 1 |
| Mohamed, AM; Saddi, AA; Shaikh, AM | 1 |
| Irak, K; Mert, H; Mert, N; Yıldırım, S | 1 |
| He, F; Liu, M; Qin, Q; Wang, G; Zhang, L; Zhang, X | 1 |
| Ayijiang, J; Chen, LN; Gong, X; Li, YN; Liu, X; Xing, T; Yan, WH; Yang, YX; Yu, Y; Zhang, CX; Zhang, M | 1 |
| Ayazoğlu, TA; Çomaklı, S; Erol, HS; Kuyrukluyıldız, U; Onk, D; Onk, OA; Özkaraca, M; Ünver, S | 1 |
| Dzugkoev, SG; Dzugkoeva, FS; Karchaidze, NM; Margieva, OI; Mozhaeva, IV | 1 |
| Bi, Y; Chen, J; Chen, L; Xu, L; Zhang, Q | 1 |
| Adeyemi, WJ; Olayaki, LA | 1 |
| Ergaz, Z; Ornoy, A; Weinstein-Fudim, L | 1 |
| Abdel-Ghaffar, A; Ahmed, EK; Ghanem, HM; Hassanin, OA; Mohamed, RG | 1 |
| Huang, L; Li, Y; Lü, G; Wang, C; Zhao, S | 1 |
| An, J; Bai, LJ; Liu, H; Liu, LH; Liu, Y; Qi, BL; Qi, BM; Wang, Q; Wang, RY; Wu, KF; Zhang, L | 1 |
| Chen, SS; Qi, MY; Wang, XT | 1 |
| Chen, XB; Gao, S; Liu, JH; Liu, X; Wang, FJ; Wang, KK | 1 |
| Gao, Q; Jia, Q; Li, ZH; Liu, XF; Ma, SF; Yang, R | 1 |
| Cai, QJ; Chen, H; Qu, XH; Xiao, M; Xie, KJ | 1 |
| Jing, HF; Wang, XM | 2 |
| Du, M; Kou, L; Liu, P; Shang, M; Wang, X; Yang, P; Zhang, B; Zhang, Y | 1 |
| Guo, XX; Ji, BP; Wang, K; Wang, Y; Zhou, F | 1 |
| Abu Bakar, AB; Md Lazin, MRML; Mohamed, M; Nna, VU | 1 |
| Delkhosh-Kasmaie, F; Farshid, AA; Imani, M; Tamaddonfard, E | 1 |
| Guo, N; Huan, Y; Li, C; Li, R; Liu, Q; Liu, S; Shen, Z; Sun, S; Wang, Y; Yang, M | 1 |
| Chen, J; Chen, X; Feng, X; Ni, H; Wu, Q; Yuan, X | 1 |
| Babri, S; Ebrahimi, H; Ebrahimi, V; Farajdokht, F; Mohaddes, G; Rahmani, G | 1 |
| Chi, Y; Kang, Y; Li, Y; Liu, W; Lu, H; Niu, H; Zhang, T | 1 |
| Chen, L; Guo, X; Li, J; Li, W; Wang, L; Wang, Z; Zhang, H; Zhang, J; Zhao, D | 1 |
| Li, X; Ling, M; Liu, C; Wang, Z; Xing, Y; Zhang, H; Zhang, M | 1 |
| Huang, J; Li, H; Li, Y; Liang, J; Liang, Q; Lu, Y; Yan, Y; Zhao, L | 1 |
| Elpeze, B; Icel, A; Icel, E; Karakurt, Y; Keskin Çimen, F; Süleyman, H; Uçak, T | 1 |
| Durmus, S; Gelisgen, R; Mirzatas, EB; Ozcelik, D; Ozsobacı, NP; Senyigit, A; Simsek, G; Tuncdemir, M; Uzun, H | 1 |
| Kaczmarczyk-Sedlak, I; Mrukwa-Kominek, E; Sedlak, L; Wojnar, W; Wyględowska-Promieńska, D; Zych, M | 1 |
| Hsu, CK; Hwang, J; Lin, CW; Shieh, DE; Shyu, YS | 1 |
| Elbe, H; Guclu, MM; Gunaltili, M; Parlakpinar, H; Polat, A; Tutun, B; Vardi, N; Yasar, EN | 1 |
| Jia, G; Jiang, T; Li, R; Li, X; Li, Y; Liu, Y; Wu, Y; Xiao, J; Xie, L; Xu, K; Xu, Z; Yuan, Y; Zhang, H; Zhong, X | 1 |
| Mabandla, M; Sibiya, N | 1 |
| Du, Z; Khan, MZH; Liu, X; Yuan, T; Zhang, Y; Zhao, Y | 1 |
| Jia, Q; Liu, XF; Ma, SF; Wang, L; Yang, R | 1 |
| Fu, Q; Hu, LL; Tian, T; Zhang, H; Zhang, KQ | 1 |
| Abdel-Daim, MM; Al Jaouni, SK; Atta, MS; El-Far, AH; Farrag, FA; Mousa, SA | 1 |
| Guo, Y; Jin, R; Wang, H; Xu, B; Yuan, C | 1 |
| Chang, CH; Chen, RF; Kuo, YR; Wang, CT | 1 |
| Li, M; Ni, Z; Wang, Y | 1 |
| He, Y; Liu, W; Mei, H; Tian, W; Xu, J; Yang, X; Zeng, YU; Zhu, J | 1 |
| Abdelkader, NF; Badawi, MA; Eitah, HE; Gamal El Din, AA; Kenawy, SA; Maklad, YA | 1 |
| Kakar, MA; Mesbahzadeh, B; Moradi-Kor, N; Rahmani, M; Rajaei, SA; Rezamohamadi, F; Seyedinia, SA; Tarahomi, P | 1 |
| Chen, ML; Chen, YF; Hu, FL; Liu, YC; Shi, YZ; Shou, QY; Si, JJ; Zheng, HQ; Zheng, YF | 1 |
| Baluchnejadmojarad, T; Khosravi, Z; Roghani, M; Sedaghat, R | 1 |
| Bashir, SO; Bin-Jaliah, I; Haidara, MA; Morsy, MD; Shatoor, A | 1 |
| Bastos, DSS; de Oliveira, LL; Ervilha, LOG; Fernandes, KM; Machado-Neves, M; Santos, FC; Sertorio, MN; Souza, ACF | 1 |
| Gao, WW; Hou, JB; Jiang, M; Li, M; Liu, L; Xia, ZY; Yuan, Q; Zhan, LY; Zhao, B | 1 |
| Dong, H; Ge, Z; Hou, H; Zhang, Q | 1 |
| Cui, Y; Hua, Q; Li, N; Li, T; Zhao, M | 1 |
| Fakharzadeh, S; Hafizi, M; Kalanaky, S; Nazaran, MH; Zardooz, H | 1 |
| Arad, M; Aravot, D; Hochhauser, E; Kornwoski, R; Nudelman, V; Peterson, SJ; Shainberg, A; Waldman, M; Zemel, R | 1 |
| Baloyi, MC; Khathi, A; Ludidi, A; Ngubane, PS; Sibiya, NH | 1 |
| Farbood, Y; Ghaderi, S; Khorsandi, L; Khoshnam, SE; Rashno, M; Sarkaki, A | 1 |
| Li, M; Zhang, D | 1 |
| Abdel Kader, DH; Al-Ani, B; Dallak, M; Eid, RA; Haidara, MA | 1 |
| Chen, GR; Chi, C; Miao, CF; Wu, G; Xu, FF | 1 |
| Ahmad, S; Aktaş, HS; Ayaz-Adakul, B; Canbey-Göret, C; Elcioglu, HK; Kabasakal, L; Kudas, I; Ozel, Y; Pençe, HH; Şekerler, T; Tetik, S | 1 |
| Hu, L; Wan, YJ; Wang, XM | 1 |
| Al Wafai, RJ | 1 |
| Bao, Y; Li, S; Liu, X; M, S; Sui, M; Xie, R; Yin, H; Zou, C | 1 |
| Anusorn, L; Chutima, S; Phatchawan, A; Varanuj, C | 1 |
| Jiang, Y; Jin, H; Li, J; Liu, N; Ren, X; Wei, Q | 1 |
| Gao, Q; Kang, PF; Li, ZH; Wang, HJ; Wang, XM; Ye, HW; Yu, Y; Zhou, H | 1 |
| Altan, N; Engin, A; Kocamanoglu, N; Kosova, F; Sepici, A | 1 |
| Capponi, JA; Catanzaro, O; Di Martino, I; Labal, E; Michieli, J; Sirois, P | 1 |
| Li, HP; Liu, YW; Lu, Q; Wang, JY; Wei, YQ; Yang, QQ; Yin, JL; Yin, XX; Zhu, X | 1 |
| Chen, H; Chen, W; Deng, X; Gu, G; Huang, W; Jin, J; Mei, Y; Qian, H; Ru, M; Wang, X; Yan, S; Yang, B | 1 |
| Feng, B; Wang, H; Xu, L; Xue, JL; Yan, XF | 1 |
| Barros, HM; Guerreiro, G; Manfredini, V; Mescka, CP; Nin, MS; Ribas, GS; Vanzin, CS; Vargas, CR; Wayhs, CA | 1 |
| Badr, BM; Badr, G; El-Elaimy, IA; Ibrahim, HM; Rabah, DM; Saad Eldien, HM | 1 |
| Chen, X; Jin, J; Jin, L; Lu, J; Ren, J; Tang, J; Wang, J; Xie, W | 1 |
| Guo, C; He, Q; Li, R; Liang, T; Xu, L; Zheng, N | 1 |
| Chen, CP; Chen, J; Min, QX; Wan, LS; Wang, YL; Xiao, ZQ; Yue, Y | 1 |
| Al-Ajmi, H; Al-Amin, M; Al-Rasheed, NM; Attia, HA; Hasan, IH; Mohamad, RA | 1 |
| Haji, AA; Japar, A; Parhat, K; Qu, SS; Wei, YY; Yan, D | 1 |
| Feng, WS; Gao, AS; Hou, QW; Ke, YY; Liu, ZY; Su, CF; Wang, WW; Wu, YY; Zhang, L; Zheng, XK | 1 |
| Prabhakar, O | 1 |
| Li, W; Lu, XH; Wang, GG; Xu, L; Zhao, X | 1 |
| Miao, J; Wang, S; Zhang, W; Zhang, Y | 1 |
| Adegoke, OA; Adekunbi, DA; Dada, KA; Morakinyo, AO | 1 |
| Fukuoka, M; Hashida, M; Ikemura, M; Kusamori, K; Nishikawa, M; Yamashita, F | 1 |
| Kim, MJ; Lim, Y | 1 |
| Isarasena, N; Patumraj, S; Sukpat, S; Wongphoom, J | 1 |
| El Sarha, A; Ismail, MA; Refaat, R; Salman, ZK; Selima, E | 1 |
| Boyom, FF; Mejiato, PC; Tchinda, BT; Teugwa, CM; Zofou, D | 1 |
| Alnoury, AM; Gad, HG; Hegazy, GA | 1 |
| Amornlerdpison, D; Lailerd, N; Lungkaphin, A; Ontawong, A; Pongchaidecha, A; Saowakon, N; Srimaroeng, C; Vivithanaporn, P | 1 |
| Arulselvan, P; Fakurazi, S; Kandasamy, M; Muniappan, BP; Sellamuthu, PS | 1 |
| Guo, F; Li, Z; Xu, L | 1 |
| Chen, JC; Liu, S; Liu, ZX; Wan, LS; Wang, YL; Xiao, ZQ; Yue, YD; Zhang, YT | 1 |
| Alexandra, T; Benoit, MZ; Désiré, DD; Florence, NT; Jonas, K; Pierre, K; Théophile, D | 1 |
| Balakrishna, N; Grama, CN; Kumar, MN; Patil, MA; Raghu, G; Reddy, GB; Suryanarayana, P | 1 |
| Gong, Y; Qi, MY; Shi, J; Yang, JJ | 1 |
| Fang, S; Ji, Y; Jiang, C; Ni, Y; Shang, X; Wang, J; Wang, Q; Yin, Z; Zhang, J | 1 |
| Budin, SB; Idris, MH; Mohamed, J; Shing, SW; Zainalabidin, S | 1 |
| Apers, S; Breynaert, A; Hermans, N; Keenoy, BM; Magielse, J; Pieters, L; Verlaet, A | 1 |
| Kim, BH; Kim, SK; Kwak, HC; Lee, JY; Lee, SY; Ma, JY; Oh, JM; Oh, SJ; Park, SK; Ryu, CS; Yun, KU | 1 |
| Aktug, H; Erbas, O; Oltulu, F; Yilmaz, M | 1 |
| Mkhwanazi, BN; Musabayane, CT; Myburg, RB; Serumula, MR; Van Heerden, FR | 1 |
| Gharbi, N; Rtibi, K; Sakly, M; Sebai, H; Selmi, S; Souli, A | 1 |
| Lee, BH; Lee, CC; Wu, SC | 1 |
| Gong, Y; Liu, HR; Qi, MY; Shi, J; Xie, GY | 1 |
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| Liu, WH; Tsao, SM; Yin, MC | 1 |
| Buko, VU; Lukivskaya, O; Patsenker, E | 1 |
| Ari, N; Bauer, V; Isik, AC; Karasu, C; Or, M; Ozoğul, C; Stefek, M; Yülek, F | 1 |
| Lin, H; Lin, ST; Qian, H; Wu, YG; Xia, LL; Zhou, D | 1 |
| Huo, TT; Liu, XN; Wang, WZ | 1 |
| Aslan, M; Orhan, DD; Orhan, N; Sezik, E; Yeşilada, E | 1 |
| Baptista, S; de Lemos, ET; Pinto, R; Reis, F; Rocha-Pereira, P; Sepodes, B; Silva, AS; Teixeira, F; Vala, H | 1 |
| Baba, F; Fadillioglu, E; Gül, M; Iraz, M; Kurcer, Z; Parlakpinar, H; Tasdemir, S; Vardi, N | 1 |
| Cai, J; Pi, H; Ruan, H; Wu, J; Zhang, Y | 1 |
| Akbulut, G; Aksakal, FN; Bulduk, E; Gonul, B; Kalkanci, A; Kustimur, S; Yetkin, I | 1 |
| Meghana, K; Ramesh, B; Sanjeev, G | 1 |
| Abraham, NG; Baldi, S; Barsacchi, R; Drummond, GS; L'Abbate, A; Masiello, P; McClung, JA; Neglia, D; Novelli, M; Ottaviano, V; Paolicchi, A; Vecoli, C | 1 |
| Bao, Y; Jia, R; Yuan, J | 1 |
| Aribal-Kocatürk, P; Büyükkağnici, DI; Kavas, GO | 2 |
| Atükeren, P; Gümüştaş, K; Kaynar, MY; Kemerdere, R; Meta Güzeyli, FM; Sanus, GZ; Tanriverdi, T | 1 |
| Li, F; Ma, JB; Shen, YS; Shi, XQ; Zhao, GH | 1 |
| Jin, L; Jin, LJ; Li, SY; Xu, YP; Xue, HY | 1 |
| Ayaz, L; Emre, M; Günay, I; Inal, T; Kavak, S; Tamer, L | 1 |
| Chandra, R; Diwakar, S; Gupta, RK; Kesari, AN; Tandon, V; Tyagi, A; Watal, G | 1 |
| Li, WH; Lin, ZQ; Wang, LX; Wu, TG | 1 |
| Gong, DX; Jiang, YJ; Kong, CZ; Liu, HB; Sun, ZX; Yang, CM | 1 |
| Harrison, HE; Johnson, M; Reece, AH | 1 |
| Karagezian, KG; Panosian, AG; Vartanian, GS | 1 |
| Chorváthová, V; Grancicová, E; Klvanová, J; Mekinová, D; Ondreicka, R; Staruchová, M; Volkovová, K | 1 |
| Yang, YK; Zhu, WY | 1 |
| Mooradian, AD | 1 |
| Angel, MF; Babovic, S; Dellon, AL; Im, MJ; Manson, PN; Ress, AM | 1 |
| Cooper, ME; Dunlop, M; Jerums, G; Soulis-Liparota, T | 1 |
| Lightbody, JH; McMaster, D; Tate, S; Trimble, ER; Young, IS | 1 |
| de la Cruz, JP; García-Campos, J; Mérida, F; Moreno, A; Sánchez de la Cuesta, F | 1 |
| Lung, CC; Mahmoud, S; Mooradian, AD; Pinnas, JL; Shah, G | 1 |
| Ciavatti, M; Gustafsson, T; Renaud, S; Ruf, JC | 1 |
| Gaál, T; Szilágyi, A; Vajdovich, P | 1 |
| Lung, CC; Meredith, K; Mooradian, AD; Pinnas, JL; Yahya, MD | 1 |
| Alptekin, N; Koçak-Toker, N; Seçkin, S; Uysal, M | 1 |
| Kumar, JS; Menon, VP | 2 |
| Bobek, P; Chorváthová, V; Jurcovicová, M; Koszeghyová, L; Volkovová, K | 1 |
| Kanashiro, M; Matsubara, T; Nakao, M; Nonoda, K; Sakamoto, N; Suzuki, O | 1 |
| Guo, SS; Liang, XC; Xie, MZ | 1 |
| Haynes, B; Josepovitz, C; Kaloyanides, GJ; Ramsammy, LS | 1 |
| Csallany, AS; Gallaher, DD; Olson, JM; Shoeman, DW | 1 |
| Lung, CC; Meinke, GC; Mooradian, AD; Pinnas, JL; Yahya, MD | 1 |
| Chancerelle, Y; Kergonou, JF | 1 |
| Baccari, GC; Frascatore, S; Papaccio, G; Pisanti, FA; Sellitti, S | 1 |
| Bravenboer, B; Gispen, WH; Marx, JJ; van Asbeck, BS; van Dam, PS; van Oirschot, JF | 2 |
| Asano, T; Futata, T; Horiuchi, S; Ikeda, K; Meng, J; Myint, T; Nagai, R; Sakata, N; Takebayashi, S; Taniguchi, N | 1 |
| Kim, H; Lim, E; Park, S | 1 |
| Favari, LP; Perez, BL; Reyes, JL; Soto, CP | 1 |
| Kedziora-Kornatowska, K; Luciak, M | 2 |
| Cabrera, ES; Montilla, PL; Muñoz de Agueda, MC; Túnez, IF; Valdelvira, ME; Vargas, JF | 1 |
| Hashimoto, T; Nawata, H; Sano, T; Umeda, F; Utsumi, H | 1 |
| Blaszczyk, J; Kedziora-Kornatowska, KZ; Luciak, M; Pawlak, W | 1 |
| Chung, SS; Lee, AY | 1 |
| Haluzík, M; Nedvídková, J; Skrha, J | 1 |
| Obrosova, IG; Stevens, MJ | 1 |
| Dettmer, D; Drews, H; Fitzl, G; Hermsdorf, V; Martin, R; Welt, K | 1 |
| Batko, J; Witmanowski, H | 1 |
| Aykaç-Toker, G; Baştar, I; Seçkin, S; Uysal, M | 1 |
| Chaya, S; Hamada, Y; Hara, T; Hotta, N; Kasuya, Y; Kato, K; Koh, N; Nakamura, J; Nakashima, E; Naruse, K; Sakakibara, F; Sasaki, H | 1 |
| Ersöz, B; Girgin, FK; Menteş, G; Sözmen, EY; Tüzün, S | 1 |
| Deng, Y; Yu, PH | 1 |
| Kedziora-Kornatowska, K | 1 |
| Fathallah, L; Greene, DA; Lang, HJ; Obrosova, IG | 1 |
| Cay, M; Dilsiz, N; Naziroğlu, M | 1 |
| Altan, VM; Dinçer, UD; Güner, S; Ozçelikay, AT; Taşyaran, V; Tay, A; Yildizoğlu-Ari, N | 1 |
| Kinalska, I; Kinalski, M; Sledziewski, A; Telejko, B; Zarzycki, W | 2 |
| Mantha, SV; Muir, AD; Prasad, K; Westcott, ND | 1 |
| Bekpinar, S; Koçak, H; Unlüçerçi, Y | 1 |
| Cao, X; Fathallah, L; Greene, DA; Obrosova, IG; Stevens, MJ; Van Huysen, C | 1 |
| Haluzík, M; Nedvídková, J | 1 |
| Kedziora-Kornatowska, KZ; Luciak, M; Paszkowski, J | 1 |
| Alper, G; Cinar, MG; Evinç, A; Ulker, S | 1 |
| Grześkowiak, E; Kozlik, J; Krauss, H; Mikrut, K; Paluszak, J; Sosnowski, P | 1 |
| Bhattacharya, S; Gupta, V; Natu, SM | 1 |
| Ali, AH; Devamanoharan, PS; Henein, M; Varma, SD; Zhao, W | 1 |
| Ahmed, I; Gillett, M; John, A; Lakhani, MS; Raza, H | 1 |
| Altavilla, D; Buemi, M; Campo, GM; Cavallari, V; Colonna, M; Cucinotta, D; Deodato, B; Galeano, M; Squadrito, F; Sturiale, A; Torre, V | 1 |
| Brun, JF; Eydoux, N; Mercier, J; Perez-Martin, A; Préfaut, C; Py, G; Raynaud, E | 1 |
| Aksoy, N; Arslan, SO; Sabuncu, T; Vural, H | 1 |
| Fathallah, L; Frank, RN; Kennedy, A; Marinescu, V; Minchenko, AG; Obrosova, IG; Stevens, MJ; Stockert, CM | 1 |
| Fathallah, L; Obrosova, IG; Stevens, MJ | 1 |
| Gladkikh, AI; Gorbenko, NI; Ivanova, OV; Poltorak, VV | 1 |
| Craven, PA; DeRubertis, FR; Liachenko, J; Melhem, MF | 1 |
| Da'as, N; Haj-Yehia, A; Kadery, B; Kleinman, Y; Lotan, C; Nassar, T | 1 |
| Baydaş, G; Celik, S; Yilmaz, O | 1 |
| Asensi, M; Desco, MC; Márquez, R; Martínez-Valls, J; Pallardó, FV; Sastre, J; Vento, M; Viña, J | 1 |
| Baydas, G; Canatan, H; Turkoglu, A | 1 |
| Gumieniczek, A; Hopkała, H; Wójtowicz, Z; Wysocka, M | 1 |
| Chwalińska, E; Jacheć, W; Tarnawski, R; Tomasik, A | 1 |
| Chen, KZ; Song, LC; Zhu, JY | 1 |
| Agaev, BA; Askerova, TA; Gadzhiev, AN; Kiazimov, IL; Velikhanova, DM | 1 |
| Antal, M; Biró, G; Biró, L; Gergely, A; Wachnik, A | 1 |
| Moser, M; Winkler, R | 1 |
| Andersen, HB; Flyvbjerg, A; Nyborg, K; Rungby, J | 1 |
| Fukui, M; Koide, H; Tomino, Y; Wang, LN; Yaguchi, Y | 1 |
| Agaeva, RB; Dzhafarov, AI | 1 |
| Low, PA; Nickander, KK | 1 |
| Ashton, MA; Yeh, LA | 1 |
| Koide, H; Tomino, Y; Watanabe, S; Yaguchi, Y | 1 |
| Acampora, A; Cotticelli, L; Pensa, M; Rinaldi, E; Simonelli, F; Teramo, P | 1 |
| Garnett, ME; Godin, DV; Goumeniouk, AD; Wohaieb, SA | 1 |
| Gavrilenko, GA; Kniazev, IuA; Rossel's, AN; Stupin, IV; Vakhrusheva, LL | 1 |
2 review(s) available for malondialdehyde and Alloxan Diabetes
| Article | Year |
|---|---|
[Immunologic relevance of malonic dialdehyde].
Topics: Alcoholism; Animals; Antibody Specificity; Cellular Senescence; Diabetes Mellitus; Diabetes Mellitus, Experimental; Humans; Immunodominant Epitopes; Malondialdehyde; Mice; Rabbits; Reperfusion Injury | 1995 |
The role of nitric oxide in the development of streptozotocin-induced diabetes mellitus: experimental and clinical implications.
Topics: Animals; Diabetes Mellitus, Experimental; Erythrocytes; Leptin; Malondialdehyde; Mice; Mice, Knockout; Nitric Oxide; Nitric Oxide Synthase; Oxidative Stress | 2000 |
1 trial(s) available for malondialdehyde and Alloxan Diabetes
| Article | Year |
|---|---|
Xanthine oxidase is involved in free radical production in type 1 diabetes: protection by allopurinol.
Topics: Allopurinol; Animals; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Double-Blind Method; Free Radical Scavengers; Free Radicals; Glutathione; Glutathione Disulfide; Heart; Humans; Kinetics; Lipid Peroxidation; Liver; Male; Malondialdehyde; Membrane Potentials; Mitochondria, Heart; Myocardium; Oxidative Stress; Rats; Rats, Wistar; Xanthine Oxidase | 2002 |
786 other study(ies) available for malondialdehyde and Alloxan Diabetes
| Article | Year |
|---|---|
Synergism effect of swimming exercise and genistein on the inflammation, oxidative stress, and VEGF expression in the retina of diabetic-ovariectomized rats.
Topics: Animals; Biomarkers; Diabetes Mellitus, Experimental; Extracellular Signal-Regulated MAP Kinases; Female; Genistein; Glucose; Glutathione; Homeostasis; Inflammation; Inflammation Mediators; Malondialdehyde; Matrix Metalloproteinase 2; MicroRNAs; NF-kappa B; Ovariectomy; Oxidative Stress; Phosphorylation; Rats, Wistar; Retina; Swimming; Vascular Endothelial Growth Factor A | 2021 |
Anti-cataract effects of coconut water in vivo and in vitro.
Topics: Animals; Antioxidants; Apoptosis; Biomarkers; Cataract; Cell Line; Cocos; Diabetes Mellitus, Experimental; Epithelial Cells; Fruit; Glutathione Peroxidase; Lens, Crystalline; Male; Malondialdehyde; Oxidative Stress; Plant Extracts; Rats, Sprague-Dawley; Superoxide Dismutase | 2021 |
Diabetic neovascularization defects in the retina are improved by genistein supplementation in the ovariectomized rat.
Topics: Animals; Antioxidants; Diabetes Mellitus, Experimental; Diabetic Retinopathy; Female; Genistein; Glutathione; Inflammation; Malondialdehyde; Ovariectomy; Oxidative Stress; Rats; Rats, Wistar; Retinal Neovascularization; Streptozocin | 2021 |
In vivo therapeutic exploring for Mori folium extract against type 2 diabetes mellitus in rats.
Topics: Animals; Biomarkers; Blood Glucose; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Hypoglycemic Agents; Insulin; Insulin Resistance; Male; Malondialdehyde; Morus; Oxidative Stress; Pancreas; Plant Extracts; Plant Leaves; Rats, Sprague-Dawley; Superoxide Dismutase | 2021 |
Topics: Animals; Antioxidants; Blood Glucose; Diabetes Mellitus, Experimental; Humans; Hyperglycemia; Malondialdehyde; Oxidative Stress; Plant Oils; Rats; Seeds; Streptozocin; Superoxide Dismutase | 2022 |
Dapagliflozin improves steatohepatitis in diabetic rats via inhibition of oxidative stress and inflammation.
Topics: Actins; Alanine Transaminase; Animals; Anti-Inflammatory Agents; Aspartate Aminotransferases; Benzhydryl Compounds; Blood Glucose; Diabetes Mellitus, Experimental; Fatty Liver; Glucosides; Insulin; Interleukin-1beta; Liver; Male; Malondialdehyde; NF-kappa B; Oxidative Stress; Rats; Sodium-Glucose Transporter 2 Inhibitors; Transforming Growth Factor beta | 2022 |
Chrysin Attenuates High Glucose-Induced BMSC Dysfunction via the Activation of the PI3K/AKT/Nrf2 Signaling Pathway.
Topics: Animals; Bone Regeneration; Cell Differentiation; Cell Survival; Cells, Cultured; Diabetes Mellitus, Experimental; Flavonoids; Glucose; Male; Malondialdehyde; Mesenchymal Stem Cells; NF-E2-Related Factor 2; Oxidative Stress; Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins c-akt; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Signal Transduction; Superoxide Dismutase | 2022 |
Anti-diabetic potential of β-boswellic acid and 11-keto-β-boswellic acid: Mechanistic insights from computational and biochemical approaches.
Topics: Animals; Blood Glucose; Boswellia; Diabetes Mellitus, Experimental; Dipeptidyl Peptidase 4; Dose-Response Relationship, Drug; Lipids; Malondialdehyde; Plant Extracts; Random Allocation; Rats; Rats, Sprague-Dawley; Streptozocin; Superoxide Dismutase; Triterpenes; Weight Loss | 2022 |
Tenofovir-silver nanoparticles conjugate ameliorates neurocognitive disorders and protects ultrastructural and cytoarchitectonic properties of the prefrontal cortex in diabetic rats.
Topics: Animals; Antioxidants; Catalase; Diabetes Mellitus, Experimental; Glutathione; Male; Malondialdehyde; Metal Nanoparticles; Neurocognitive Disorders; Prefrontal Cortex; Rats; Rats, Sprague-Dawley; Silver; Superoxide Dismutase; Tenofovir | 2022 |
Effect of oligosaccharides on the antioxidant, lipid and inflammatory profiles of rats with streptozotocin-induced diabetes mellitus.
Topics: 8-Hydroxy-2'-Deoxyguanosine; Animals; Antioxidants; Blood Glucose; Diabetes Mellitus, Experimental; Interleukin-6; Male; Malondialdehyde; Oligosaccharides; Rats; Rats, Wistar; Streptozocin; Triglycerides | 2022 |
Polyethylene glycol capped gold nanoparticles ameliorate renal ischemia-reperfusion injury in diabetic mice through AMPK-Nrf2 signaling pathway.
Topics: Acute Kidney Injury; Adenosine; AMP-Activated Protein Kinases; Animals; Antioxidants; Creatinine; Diabetes Mellitus, Experimental; Gold; Kidney; Male; Malondialdehyde; Metal Nanoparticles; Mice; NF-E2-Related Factor 2; Oxidative Stress; Phosphatidylinositol 3-Kinases; Polyethylene Glycols; Proto-Oncogene Proteins c-akt; Reperfusion Injury; Signal Transduction; Streptozocin; Tumor Necrosis Factor-alpha | 2022 |
Effects of antidiabetic agents on Alzheimer's disease biomarkers in experimentally induced hyperglycemic rat model by streptozocin.
Topics: Acetylcholinesterase; Alzheimer Disease; Amyloid beta-Peptides; Amyloid Precursor Protein Secretases; Animals; Biomarkers; Cholesterol; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Donepezil; Glucose; Glyburide; Glycated Hemoglobin; Hypoglycemic Agents; Insulin Glargine; Male; Malondialdehyde; Metformin; Microtubule-Associated Proteins; Nitric Oxide; Rats; Rats, Wistar; Streptozocin; Triglycerides; Tumor Necrosis Factor-alpha | 2022 |
Ameliorative role of Cyanus depressus (M.Bieb.) Soják plant extract against diabetes-associated oxidative-stress-induced liver, kidney, and pancreas damage in rats.
Topics: Alanine Transaminase; Animals; Antioxidants; Apigenin; Aspartate Aminotransferases; Blood Glucose; Catalase; Chromatography, Liquid; Diabetes Mellitus, Experimental; Flavonoids; Glutathione; Glutathione Transferase; Glyburide; Glycated Hemoglobin; Hydroxybenzoates; Hypoglycemic Agents; Kidney; Lactate Dehydrogenases; Liver; Malondialdehyde; Oxidative Stress; Pancreas; Phenols; Phytochemicals; Plant Extracts; Quinic Acid; Rats; Streptozocin; Tandem Mass Spectrometry | 2022 |
Betanin alleviates oxidative stress through the Nrf2 signaling pathway in the liver of STZ-induced diabetic rats.
Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Betacyanins; Catalase; Diabetes Mellitus, Experimental; Glutathione; Liver; Malondialdehyde; NF-E2-Related Factor 2; Oxidative Stress; Rats; Signal Transduction; Superoxide Dismutase | 2022 |
Sodium houttuyfonate protects against cardiac injury by regulating cardiac energy metabolism in diabetic rats.
Topics: Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphatases; Adenosine Triphosphate; Alkanes; AMP-Activated Protein Kinases; Animals; Aspartate Aminotransferases; Cholesterol; Diabetes Mellitus, Experimental; Energy Metabolism; Heart Injuries; Lipoproteins, HDL; Lipoproteins, LDL; Malondialdehyde; Natriuretic Peptide, Brain; Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha; Phosphocreatine; PPAR gamma; Rats; Rats, Sprague-Dawley; RNA, Messenger; Streptozocin; Sulfites; Triglycerides | 2022 |
Effect of L-serine on oxidative stress markers in the kidney of streptozotocin-induced diabetic mice.
Topics: Animals; Antioxidants; Blood Glucose; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Kidney; Male; Malondialdehyde; Mice; Mice, Inbred C57BL; Oxidative Stress; Streptozocin; Superoxide Dismutase | 2023 |
Effects of
Topics: Animals; Antioxidants; Diabetes Mellitus, Experimental; Ethanol; Lamiaceae; Male; Malondialdehyde; Nitric Oxide; Plant Extracts; Rats; Rats, Wistar | 2023 |
Larrea divaricata Cav. aqueous extract and nordihydroguariaretic acid modulate oxidative stress in submandibular glands of diabetic rats: a buccal protective in diabetes.
Topics: Animals; Antioxidants; Diabetes Mellitus, Experimental; Female; Larrea; Malondialdehyde; Masoprocol; Oxidative Stress; Oxidoreductases; Plant Extracts; Rats; Rats, Wistar; Submandibular Gland | 2019 |
Hesperidin ameliorates pancreatic β-cell dysfunction and apoptosis in streptozotocin-induced diabetic rat model.
Topics: Animals; Apoptosis; Apoptosis Regulatory Proteins; Blood Glucose; Diabetes Mellitus, Experimental; Eating; Endoplasmic Reticulum Stress; Glutathione Peroxidase; Heat-Shock Proteins; Hesperidin; Homeodomain Proteins; Inflammation; Insulin; Insulin-Secreting Cells; Male; Malondialdehyde; Oxidative Stress; Pancreas; Protective Agents; Rats; Superoxide Dismutase; Trans-Activators; Transcription Factor CHOP; Tumor Necrosis Factor-alpha; Tyrosine | 2019 |
Fucoxanthin-Rich Brown Algae Extract Improves Male Reproductive Function on Streptozotocin-Nicotinamide-Induced Diabetic Rat Model.
Topics: Animals; Antioxidants; Blood Glucose; Cell Survival; Diabetes Mellitus, Experimental; Disease Models, Animal; Inflammation Mediators; Insulin; Insulin Resistance; Kisspeptins; Male; Malondialdehyde; Mice; Niacinamide; Nitric Oxide; Oxidative Stress; Phaeophyceae; Rats, Sprague-Dawley; RAW 264.7 Cells; Reactive Oxygen Species; Receptors, Kisspeptin-1; Reproduction; RNA, Messenger; Spermatozoa; Streptozocin; Suppressor of Cytokine Signaling 3 Protein; Testis; Xanthophylls | 2019 |
Effects of naringenin on vascular changes in prolonged hyperglycaemia in fructose-STZ diabetic rat model.
Topics: Animals; Diabetes Mellitus, Experimental; Drug Synergism; Flavanones; Fructose; Hyperglycemia; Lipid Peroxidation; Lipids; Male; Malondialdehyde; Metformin; Oxidative Stress; Random Allocation; Rats; Rats, Sprague-Dawley; Streptozocin | 2019 |
Synthesis, structural characterization and in vivo anti-diabetic evaluation of some new sulfonylurea derivatives in normal and silicate coated nanoparticle forms as anti-hyperglycemic agents.
Topics: Animals; Antioxidants; Blood Glucose; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Dose-Response Relationship, Drug; Glutathione; Hyperglycemia; Hypoglycemic Agents; Malondialdehyde; Molecular Structure; Nanoparticles; Particle Size; Rats; Streptozocin; Structure-Activity Relationship; Sulfonylurea Compounds; Surface Properties | 2019 |
Protective effects of betaine on diabetic induced disruption of the male mice blood-testis barrier by regulating oxidative stress-mediated p38 MAPK pathways.
Topics: Animals; Antioxidants; Betaine; Blood-Testis Barrier; Catalase; Diabetes Mellitus, Experimental; Disease Models, Animal; Glutathione; Lycium; Male; Malondialdehyde; Mice; Mice, Inbred ICR; Oxidative Stress; p38 Mitogen-Activated Protein Kinases; Protective Agents; Reactive Oxygen Species; Signal Transduction; Superoxide Dismutase; Testis | 2019 |
HPLC-ESI- MS/MS analysis of beet (Beta vulgaris) leaves and its beneficial properties in type 1 diabetic rats.
Topics: Animals; Antioxidants; Atherosclerosis; Beta vulgaris; Blood Glucose; Body Weight; Chromatography, High Pressure Liquid; Cytokines; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Female; Glutathione; Humans; Inflammation Mediators; Lipids; Liver; Male; Malondialdehyde; Molecular Docking Simulation; Phenols; Phytochemicals; Phytotherapy; Plant Extracts; Plant Leaves; PPAR gamma; Rats, Wistar; Spectrometry, Mass, Electrospray Ionization; Tandem Mass Spectrometry; Toxicity Tests, Acute | 2019 |
Protective effects of Salidroside on spermatogenesis in streptozotocin induced type-1 diabetic male mice by inhibiting oxidative stress mediated blood-testis barrier damage.
Topics: Animals; Antioxidants; Blood-Testis Barrier; Catalase; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Glucosides; Glutathione; Male; Malondialdehyde; Mice; Oxidative Stress; Phenols; Protective Agents; Reactive Oxygen Species; Sperm Count; Spermatogenesis; Spermatozoa; Streptozocin; Superoxide Dismutase; Testis | 2020 |
Isorhamnetin exerts neuroprotective effects in STZ-induced diabetic rats via attenuation of oxidative stress, inflammation and apoptosis.
Topics: Animals; Apoptosis; Blood Glucose; Body Weight; Diabetes Mellitus, Experimental; DNA Fragmentation; Inflammation; Male; Malondialdehyde; Neurons; Neuroprotective Agents; Oxidative Stress; Pain; Pain Measurement; Quercetin; Rats; Rats, Wistar; Reactive Nitrogen Species; Reactive Oxygen Species | 2019 |
Melatonin reverses depressive and anxiety like-behaviours induced by diabetes: involvement of oxidative stress, age, rage and S100B levels in the hippocampus and prefrontal cortex of rats.
Topics: Animals; Anxiety; Depression; Diabetes Mellitus, Experimental; Hippocampus; Malondialdehyde; Melatonin; Oxidative Stress; Prefrontal Cortex; Rats; Rats, Wistar; Receptor for Advanced Glycation End Products; S100 Calcium Binding Protein beta Subunit | 2022 |
Zafirlukast, a Cysteinyl Leukotriene Receptor 1 Antagonist, Reduces the Effect of Advanced Glycation End-Products in Rat Renal Mesangial Cells In Vitro.
Topics: Animals; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Glutathione Peroxidase; Glycation End Products, Advanced; Indoles; Inflammation; Malondialdehyde; Mesangial Cells; Oxidative Stress; Phenylcarbamates; Rats; Reactive Oxygen Species; Receptors, Leukotriene; Sulfonamides; Superoxide Dismutase; Tosyl Compounds; Tumor Necrosis Factor-alpha | 2019 |
Aqueous Extracts of Se-Enriched
Topics: Animals; Antioxidants; Basidiomycota; Diabetes Mellitus, Experimental; Diet, High-Fat; Extracellular Signal-Regulated MAP Kinases; Glucose Tolerance Test; JNK Mitogen-Activated Protein Kinases; Liver; Liver Diseases; Male; Malondialdehyde; Mice; Mice, Inbred C57BL; Oxidative Stress; p38 Mitogen-Activated Protein Kinases; Receptor for Advanced Glycation End Products; Selenium; Streptozocin; Tumor Necrosis Factor-alpha | 2020 |
Neuroprotective Dipeptide Noopept Prevents DNA Damage in Mice with Modeled Prediabetes.
Topics: Animals; Blood Glucose; Diabetes Mellitus, Experimental; Dipeptides; DNA Damage; Hyperglycemia; Insulin-Secreting Cells; Kidney; Liver; Male; Malondialdehyde; Mice; Mice, Inbred BALB C; Neuroprotective Agents; Prediabetic State; Streptozocin | 2019 |
Effect of garden cress in reducing blood glucose, improving blood lipids, and reducing oxidative stress in a mouse model of diabetes induced by a high-fat diet and streptozotocin.
Topics: Animals; Antioxidants; Blood Glucose; Catalase; Cholesterol, HDL; Cholesterol, LDL; Diabetes Mellitus, Experimental; Diet, High-Fat; DNA Fragmentation; Gene Expression Regulation; Glucose Transporter Type 4; Glutathione; Glutathione Peroxidase; Glycated Hemoglobin; Hypoglycemic Agents; Insulin; Insulin Receptor Substrate Proteins; Lepidium sativum; Lipid Peroxides; Lipids; Male; Malondialdehyde; Mice; Mice, Inbred ICR; Oxidative Stress; Phosphatidylinositol 3-Kinases; Plant Extracts; Superoxide Dismutase; Triglycerides | 2020 |
The effect of cold atmospheric plasma on diabetes-induced enzyme glycation, oxidative stress, and inflammation; in vitro and in vivo.
Topics: Animals; Antioxidants; Biomarkers; Cytokines; Diabetes Mellitus; Diabetes Mellitus, Experimental; Enzyme Induction; Glutathione Peroxidase; Glycation End Products, Advanced; Glycosylation; Inflammation; Lipoproteins, LDL; Male; Malondialdehyde; Mice; Mice, Inbred BALB C; Oxidative Stress; Plasma Gases; Streptozocin; Tumor Necrosis Factor-alpha | 2019 |
Cyclohexane extract of walnut leaves improves indices of oxidative stress, total homocysteine and lipids profiles in streptozotocin-induced diabetic rats.
Topics: Animals; Blood Glucose; Catalase; Cholesterol; Cholesterol, LDL; Cholesterol, VLDL; Cyclohexanes; Diabetes Mellitus, Experimental; Glutathione Peroxidase; Homocysteine; Juglans; Lipid Metabolism; Male; Malondialdehyde; Oxidative Stress; Phytotherapy; Plant Extracts; Plant Leaves; Rats; Rats, Sprague-Dawley; Superoxide Dismutase; Triglycerides | 2020 |
Exendin-4 regulates endoplasmic reticulum stress to protect endothelial progenitor cells from high-glucose damage.
Topics: Animals; Apoptosis; Body Weight; Cell Survival; Cells, Cultured; Diabetes Mellitus, Experimental; Endoplasmic Reticulum Stress; Endothelial Progenitor Cells; Exenatide; Glucose; Male; Malondialdehyde; MAP Kinase Signaling System; Mice; Mice, Inbred C57BL; Reactive Oxygen Species; Superoxide Dismutase | 2020 |
The anti-inflammatory effect of omega-3 polyunsaturated fatty acids dramatically decreases by iron in the hippocampus of diabetic rats.
Topics: Animals; Diabetes Mellitus, Experimental; Fatty Acids, Omega-3; Ferrous Compounds; Hippocampus; Inflammation; Malondialdehyde; Microglia; Oxidative Stress; Rats; Rats, Wistar; Receptor for Advanced Glycation End Products; Tumor Necrosis Factor-alpha | 2020 |
Exogenous melatonin restrains neuroinflammation in high fat diet induced diabetic rats through attenuating indoleamine 2,3-dioxygenase 1 expression.
Topics: Acetylcholinesterase; Animals; Anti-Inflammatory Agents; Antioxidants; Cytokines; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Diet, High-Fat; Glutathione; Hippocampus; Indoleamine-Pyrrole 2,3,-Dioxygenase; Inflammation; Male; Malondialdehyde; Melatonin; Nervous System Diseases; Nitric Oxide Synthase Type II; Oxidative Stress; Rats; Rats, Sprague-Dawley; Signal Transduction | 2020 |
New combination therapy of gliclazide and quercetin for protection against STZ-induced diabetic rats.
Topics: Animals; Blood Glucose; C-Peptide; Cholesterol; Diabetes Mellitus, Experimental; Drug Therapy, Combination; Gliclazide; Glutathione; Hypoglycemic Agents; Inflammation; Insulin; Islets of Langerhans; Male; Malondialdehyde; NF-kappa B; Oxidative Stress; Pancreas; Quercetin; Rats; Rats, Wistar; Streptozocin; Superoxide Dismutase; Triglycerides; Tumor Necrosis Factor-alpha | 2020 |
Effects of thiamine treatment on oxidative stress in experimental diabetes.
Topics: Animals; Antioxidants; Blood Glucose; Diabetes Mellitus, Experimental; Malondialdehyde; Oxidative Stress; Rats; Rats, Wistar; Superoxide Dismutase; Thiamine | 2020 |
Platelet-rich plasma improves impaired glucose hemostasis, disrupted insulin secretion, and pancreatic oxidative stress in streptozotocin-induced diabetic rat.
Topics: Animals; Antioxidants; Biomarkers; Blood Glucose; Catalase; Diabetes Mellitus, Experimental; Disease Models, Animal; Glucose; Glucose Tolerance Test; Hemostasis; Insulin; Intercellular Signaling Peptides and Proteins; Islets of Langerhans; Male; Malondialdehyde; Oxidative Stress; Pancreas; Platelet-Rich Plasma; Rats; Rats, Sprague-Dawley; Streptozocin; Superoxide Dismutase | 2019 |
Consumption of the Syrian mesquite plant (
Topics: Animals; Antioxidants; Biomarkers; Blood Glucose; Diabetes Mellitus, Experimental; Fruit; Hypoglycemic Agents; Liver; Malondialdehyde; Plant Extracts; Prosopis; Rats; Seeds; Syria | 2022 |
Effects of curcumin on sperm quality, lipid profile, antioxidant activity and histopathological changes in streptozotocin-induced diabetes in rats.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Blood Glucose; Caspase 3; Catalase; Cholesterol; Curcumin; Diabetes Mellitus, Experimental; Glutathione; Lipoproteins, LDL; Male; Malondialdehyde; Rats; Rats, Wistar; Sperm Motility; Spermatozoa; Testis; Testosterone; Triglycerides | 2020 |
Effect of Graviola (Annona Muricata l.) and Ginger (Zingiber Officinale Roscoe) on Diabetes Mellitus Induced in Male Wistar Albino Rats.
Topics: Animals; Annona; Antioxidants; Apoptosis; bcl-2-Associated X Protein; Biomarkers; Blood Glucose; Diabetes Mellitus, Experimental; Gene Expression Regulation; Glucose Transporter Type 2; Glycated Hemoglobin; Insulin; Insulin Resistance; Liver; Liver Function Tests; Male; Malondialdehyde; NF-kappa B; Oxidative Stress; Plant Extracts; Rats, Wistar; Receptor, Insulin; Tumor Necrosis Factor-alpha; Tumor Suppressor Protein p53; Zingiber officinale | 2019 |
Modulatory effect of tropisetron in the liver of streptozotocin-induced diabetes in rats: biochemical and histological evidence.
Topics: Animals; Antioxidants; Diabetes Mellitus, Experimental; Glutathione Peroxidase; Glyburide; Liver; Male; Malondialdehyde; Oxidative Stress; Rats; Rats, Wistar; Serotonin 5-HT3 Receptor Antagonists; Superoxide Dismutase; Tropisetron | 2020 |
Kidney-targeted baicalin-lysozyme conjugate ameliorates renal fibrosis in rats with diabetic nephropathy induced by streptozotocin.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Blood Glucose; Cholesterol; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Drug Carriers; Drug Delivery Systems; Fibrosis; Flavonoids; Insulin; Kidney; Malondialdehyde; Muramidase; Rats; Triglycerides | 2020 |
The evaluation of early stage oxidative status in streptozotocin induced diabetes in rats.
Topics: Animals; Arginase; Blood Glucose; Catalase; Diabetes Mellitus, Experimental; Insulin; Male; Malondialdehyde; Nitric Oxide; Oxidative Stress; Rats; Rats, Sprague-Dawley; Rats, Wistar; Streptozocin; Superoxide Dismutase | 2022 |
Effects of renal ischemia injury on brain in diabetic and non-diabetic rats: Role of angiotensin II type 2 receptor and angiotensin-converting enzyme 2.
Topics: Angiotensin-Converting Enzyme 2; Animals; Brain; Diabetes Mellitus, Experimental; Diminazene; Hyperglycemia; Imidazoles; Kidney Diseases; Kidney Tubules; Male; Malondialdehyde; Nitrites; Rats, Wistar; Receptor, Angiotensin, Type 2; Reperfusion Injury; Sulfonamides; Thiophenes | 2020 |
Troxerutin attenuates cognitive decline in the hippocampus of male diabetic rats by inhibiting NADPH oxidase and activating the Nrf2/ARE signaling pathway.
Topics: Animals; Antioxidants; Diabetes Mellitus, Experimental; Hippocampus; Hydroxyethylrutoside; Male; Malondialdehyde; Maze Learning; NADPH Oxidases; NF-E2-Related Factor 2; Oxidative Stress; Rats; Rats, Sprague-Dawley; Signal Transduction | 2020 |
Mesenchymal stem cells versus curcumin in enhancing the alterations in the cerebellar cortex of streptozocin-induced diabetic albino rats. The role of GFAP, PLC and α-synuclein.
Topics: alpha-Synuclein; Animals; Blood Glucose; Cerebellar Cortex; Curcumin; Diabetes Mellitus, Experimental; Glial Fibrillary Acidic Protein; Glutathione; Male; Malondialdehyde; Mesenchymal Stem Cells; Oxidative Stress; Purkinje Cells; Rats; Signal Transduction; Superoxide Dismutase; Type C Phospholipases | 2020 |
Nanoparticles of Antroquinonol-Rich Extract from Solid-State-Cultured
Topics: Animals; Antrodia; Blood Glucose; Diabetes Mellitus, Experimental; Disease Models, Animal; Fasting; Glutathione Peroxidase; Humans; Insulin; Kidney; Liver; Male; Malondialdehyde; Nanoparticles; Oxidative Stress; Rats, Sprague-Dawley; Reproduction; Sperm Count; Sperm Motility; Streptozocin; Superoxide Dismutase; Testis; Ubiquinone | 2020 |
Biochemical Evidence Indicates the Preventive Effect of Resveratrol and Nicotinamide in the Treatment of STZ-induced Diabetic Cataract.
Topics: Aldehyde Reductase; Animals; Antioxidants; Blood Glucose; Cataract; Diabetes Mellitus, Experimental; Drug Therapy, Combination; Hyperglycemia; Injections, Intraperitoneal; Lipid Peroxidation; Male; Malondialdehyde; Niacinamide; Oxidative Stress; Poly(ADP-ribose) Polymerases; Rats; Rats, Sprague-Dawley; Resveratrol; Sodium-Potassium-Exchanging ATPase; Sorbitol; Streptozocin; Vitamin B Complex | 2021 |
Centella asiatica alleviates diabetes-induced changes in fatty acid profile and oxidative damage in rat testis.
Topics: Animals; Antioxidants; Centella; Diabetes Mellitus, Experimental; Fatty Acids; Glutathione; Glutathione Peroxidase; Male; Malondialdehyde; Oxidative Stress; Rats; Testis | 2020 |
Bergenin Reduces Experimental Painful Diabetic Neuropathy by Restoring Redox and Immune Homeostasis in the Nervous System.
Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Benzopyrans; Cytokines; Diabetes Mellitus, Experimental; Diabetic Neuropathies; Glutathione Peroxidase; Homeostasis; Immune System; Male; Malondialdehyde; Mice; Mice, Inbred C57BL; Nervous System; Neuralgia; NF-E2-Related Factor 2; Nitric Oxide; Nitric Oxide Synthase Type II; Oxidation-Reduction; Oxidative Stress; Streptozocin | 2020 |
Modulatory role of imatinib mesylate on pancreatic β-cells' secretory functions in an STZ rat model of diabetes mellitus.
Topics: Administration, Oral; Animals; Antigens, CD; Antigens, Differentiation, Myelomonocytic; Antioxidants; Biomarkers; Blood Glucose; Body Weight; Caspase 3; Catalase; Diabetes Mellitus, Experimental; Disease Models, Animal; Glucagon; Glutathione; Imatinib Mesylate; Insulin; Insulin-Secreting Cells; Male; Malondialdehyde; Organ Size; Oxidation-Reduction; Oxidative Stress; Rats, Sprague-Dawley; Streptozocin; Superoxide Dismutase | 2020 |
Expression of α-Klotho Is Downregulated and Associated with Oxidative Stress in the Lens in Streptozotocin-induced Diabetic Rats.
Topics: Animals; Blood Glucose; Blotting, Western; Diabetes Mellitus, Experimental; Down-Regulation; Enzyme-Linked Immunosorbent Assay; Glutathione; Glutathione Peroxidase; Klotho Proteins; Lens, Crystalline; Male; Malondialdehyde; NF-E2-Related Factor 2; Oxidative Stress; Rats; Rats, Wistar; Streptozocin | 2021 |
Attenuation of Cardiac Autonomic Neuropathy by Escin in Diabetic Rats.
Topics: Animals; Antioxidants; Autonomic Nervous System Diseases; Catalase; Diabetes Mellitus, Experimental; Diabetic Neuropathies; Escin; Glutathione; Heart; Heart Diseases; Heart Rate; Hemodynamics; Male; Malondialdehyde; Matrix Metalloproteinase 9; Neuroprotective Agents; Oxidative Stress; Rats, Sprague-Dawley; Superoxide Dismutase; Vagus Nerve | 2021 |
Evaluation of the modulation of nitric oxide synthase expression in the cerebellum of diabetic albino rats and the possible protective effect of ferulic acid.
Topics: Animals; Antioxidants; Blood Glucose; Cerebellum; Coumaric Acids; Diabetes Mellitus, Experimental; Gene Expression Regulation; Hypoglycemic Agents; Insulin; Male; Malondialdehyde; Nitric Oxide; Nitric Oxide Synthase Type I; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Oxidative Stress; Rats; Rotarod Performance Test; Streptozocin; Superoxide Dismutase | 2020 |
Metformin attenuated histopathological ocular deteriorations in a streptozotocin-induced hyperglycemic rat model.
Topics: Animals; Claudin-1; Diabetes Complications; Diabetes Mellitus, Experimental; Eye Diseases; Glutathione; Hyperglycemia; Hypoglycemic Agents; Male; Malondialdehyde; Metformin; Rats, Sprague-Dawley; Streptozocin; Tumor Necrosis Factor-alpha; Vascular Endothelial Growth Factor A | 2021 |
Mechanism of Albuminuria Reduction by Chymase Inhibition in Diabetic Mice.
Topics: Albuminuria; Animals; Biomarkers; Blood Glucose; Body Weight; Chymases; Creatine; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Disease Models, Animal; Gene Expression; Immunohistochemistry; Malondialdehyde; Mast Cells; Mice; NADPH Oxidase 4; RNA, Messenger | 2020 |
Correlations between inflammatory response, oxidative stress, intestinal pathological damage and intestinal flora variation in rats with type 2 diabetes mellitus.
Topics: Animals; C-Reactive Protein; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Endotoxins; Gastrointestinal Microbiome; Glycated Hemoglobin; Inflammation; Intestines; Male; Malondialdehyde; Oxidative Stress; Rats, Sprague-Dawley; Superoxide Dismutase; Tumor Necrosis Factor-alpha | 2020 |
The Protective Effects of Lupine (Lupinus albus) Fruit Extract Against to Destructive Effects of Hyperglycemia in Type I Diabetic Rats.
Topics: Animals; Antioxidants; Blood Glucose; Cytoprotection; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Fruit; Hyperglycemia; Lipid Peroxidation; Liver; Lupinus; Male; Malondialdehyde; Muscles; Oxidative Stress; Plant Extracts; Rats; Rats, Wistar | 2021 |
Apigenin-Loaded Solid Lipid Nanoparticle Attenuates Diabetic Nephropathy Induced by Streptozotocin Nicotinamide Through Nrf2/HO-1/NF-kB Signalling Pathway.
Topics: Animals; Antioxidants; Apigenin; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Drug Delivery Systems; Heme Oxygenase (Decyclizing); Kidney; Lipids; Male; Malondialdehyde; Nanoparticles; NF-E2-Related Factor 2; NF-kappa B; Oxidative Stress; Rats; Signal Transduction; Streptozocin; Superoxide Dismutase | 2020 |
Effect of camel milk protein hydrolysates against hyperglycemia, hyperlipidemia, and associated oxidative stress in streptozotocin (STZ)-induced diabetic rats.
Topics: Animals; Antioxidants; Blood Glucose; Camelus; Diabetes Mellitus, Experimental; Hypoglycemic Agents; Hypolipidemic Agents; Insulin-Secreting Cells; Lipid Peroxidation; Liver; Male; Malondialdehyde; Milk; Milk Proteins; Oxidative Stress; Protein Hydrolysates; Rats | 2021 |
Effects of Cultured
Topics: Adenosine; Animals; Blood Glucose; Blood Pressure; Cordyceps; Deoxyadenosines; Diabetes Mellitus, Experimental; Fasting; Male; Malondialdehyde; Nitric Oxide Synthase; Organ Size; Penile Erection; Rats, Sprague-Dawley; Reproduction; Sexual Behavior, Animal; Spermatozoa; Streptozocin; Superoxide Dismutase; Testis; Testosterone | 2020 |
Melatonin reverses cognitive deficits in streptozotocin-induced type 1 diabetes in the rat through attenuation of oxidative stress and inflammation.
Topics: Acetylcholinesterase; Animals; Antioxidants; Avoidance Learning; Cognitive Dysfunction; Diabetes Mellitus, Experimental; Hippocampus; Inflammation; Male; Malondialdehyde; Maze Learning; Melatonin; Neuroprotective Agents; Oxidative Stress; Rats; Rats, Wistar; Reactive Oxygen Species; Superoxide Dismutase | 2021 |
Curative Effect of Catechin Isolated from
Topics: alpha-Amylases; alpha-Glucosidases; Animals; Antioxidants; Benzothiazoles; Biphenyl Compounds; Blood Glucose; Body Weight; Catechin; Diabetes Mellitus, Experimental; Elaeagnaceae; Free Radical Scavengers; Free Radicals; Fruit; Glyburide; Hyperglycemia; Hyperlipidemias; Hypoglycemic Agents; In Vitro Techniques; Inhibitory Concentration 50; Kidney; Lipid Peroxides; Lipids; Malondialdehyde; Phenol; Picrates; Plant Extracts; Rats; Rats, Sprague-Dawley; Streptozocin; Sulfonic Acids | 2020 |
Melatonin and prolonged physical activity attenuated the detrimental effects of diabetic condition on murine cardiac tissue.
Topics: Animals; Antioxidants; Apoptosis; Caspase 3; Connexin 43; Diabetes Mellitus, Experimental; Glutathione Peroxidase; Inflammation; Male; Malondialdehyde; Melatonin; Mice, Inbred BALB C; Microvessels; Myocardium; Physical Conditioning, Animal; Sirtuin 1; Superoxide Dismutase; Tumor Necrosis Factor-alpha | 2021 |
Calcitriol Supplementation Ameliorates Microvascular Endothelial Dysfunction in Vitamin D-Deficient Diabetic Rats by Upregulating the Vascular eNOS Protein Expression and Reducing Oxidative Stress.
Topics: Animals; Calcitriol; Diabetes Mellitus, Experimental; Dietary Supplements; Endothelium, Vascular; Male; Malondialdehyde; Mesenteric Arteries; Microvessels; Nitric Oxide Synthase Type III; Nitroprusside; Oxidative Stress; Phenylephrine; Rats, Sprague-Dawley; Superoxide Dismutase; Up-Regulation; Vasoconstriction; Vasodilation; Vitamin D Deficiency | 2021 |
Vitexin, a fenugreek glycoside, ameliorated obesity-induced diabetic nephropathy via modulation of NF-κB/IkBα and AMPK/ACC pathways in mice.
Topics: Acetyl-CoA Carboxylase; AMP-Activated Protein Kinases; Animals; Anti-Obesity Agents; Apigenin; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Diet, High-Fat; Gene Expression Regulation; Hypoglycemic Agents; I-kappa B Kinase; Male; Malondialdehyde; Mice; Mice, Inbred C57BL; NF-kappa B; Obesity; Plant Extracts; Signal Transduction; Superoxide Dismutase; Trigonella; Tumor Necrosis Factor-alpha | 2021 |
Gastric Electrical Pacing Reduces Apoptosis of Interstitial Cells of Cajal via Antioxidative Stress Effect Attributing to Phenotypic Polarization of M2 Macrophages in Diabetic Rats.
Topics: Animals; Apoptosis; Cell Polarity; Diabetes Mellitus, Experimental; Electroacupuncture; Electrophysiological Phenomena; Heme Oxygenase-1; Interstitial Cells of Cajal; Macrophages; Male; Malondialdehyde; NF-E2-Related Factor 2; NF-kappa B; Oxidative Stress; Phosphorylation; Proto-Oncogene Proteins c-kit; Rats, Sprague-Dawley; Reactive Oxygen Species; Signal Transduction; Stem Cell Factor; Stomach; Superoxide Dismutase | 2021 |
Vanillin exerts therapeutic effects against hyperglycemia-altered glucose metabolism and purinergic activities in testicular tissues of diabetic rats.
Topics: Acetylcholinesterase; Animals; Antioxidants; Benzaldehydes; Blood Glucose; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Glucose; Humans; Hyperglycemia; Hypoglycemic Agents; Male; Malondialdehyde; Metformin; NF-E2-Related Factor 2; Oxidation-Reduction; Oxidative Stress; Plant Extracts; Rats; Rats, Sprague-Dawley; Superoxide Dismutase; Testicular Diseases | 2021 |
Crocin Improves Oxidative Stress in Testicular Tissues of Streptozotocin-Induced Diabetic Rats.
Topics: Animals; Antioxidants; Carotenoids; Catalase; Diabetes Mellitus, Experimental; Malondialdehyde; Oxidative Stress; Rats; Rats, Wistar; Streptozocin; Superoxide Dismutase | 2021 |
Efonidipine Exerts Cerebroprotective Effect by Down-regulation of TGF-β/SMAD-2-Dependent Signaling Pathway in Diabetic Rats.
Topics: Acetylcholinesterase; Animals; Brain; Calcium Channel Blockers; Diabetes Mellitus, Experimental; Dihydropyridines; Infarction, Middle Cerebral Artery; Male; Malondialdehyde; Neuroprotective Agents; Nitrites; Nitrophenols; Organophosphorus Compounds; Oxidative Stress; Rats; Rats, Sprague-Dawley; Signal Transduction; Smad2 Protein; Transforming Growth Factor beta; Vascular Endothelial Growth Factor A | 2021 |
Effects of Quercetin and Coenzyme Q10 on Biochemical, Molecular, and Morphological Parameters of Skeletal Muscle in Trained Diabetic Rats.
Topics: Animals; Diabetes Mellitus, Experimental; Fibronectins; Humans; Male; Malondialdehyde; Muscle, Skeletal; Quercetin; Rats; Ubiquinone | 2022 |
A novel layered double hydroxide-hesperidin nanoparticles exert antidiabetic, antioxidant and anti-inflammatory effects in rats with diabetes.
Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Blood Glucose; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Glucose; Hesperidin; Hydroxides; Hypoglycemic Agents; Insulin; Male; Malondialdehyde; Nanoparticles; Oxidative Stress; PPAR gamma; Rats | 2021 |
Protective effects of L-carnitine on reproductive capacity in rats with diabetes.
Topics: Animals; Arterial Pressure; Carnitine; Diabetes Mellitus, Experimental; Erectile Dysfunction; Follicle Stimulating Hormone; Luteinizing Hormone; Male; Malondialdehyde; Rats; Rats, Sprague-Dawley; Sperm Count; Spermatozoa; Testosterone | 2021 |
Albiflorin alleviates cognitive dysfunction in STZ-induced rats.
Topics: Animals; Bridged-Ring Compounds; Cognitive Dysfunction; Diabetes Mellitus, Experimental; Hippocampus; HMGB1 Protein; Male; Malondialdehyde; Maze Learning; NF-kappa B; Oxidative Stress; Plaque, Amyloid; Rats; Rats, Wistar; Signal Transduction; Streptozocin | 2021 |
Ginsenoside Re Ameliorates Brain Insulin Resistance and Cognitive Dysfunction in High Fat Diet-Induced C57BL/6 Mice.
Topics: Animals; Brain; Cholesterol; Cognitive Dysfunction; Diabetes Mellitus, Experimental; Ginsenosides; Humans; Insulin; Insulin Resistance; Male; Malondialdehyde; Mice; Mice, Inbred C57BL; Triglycerides | 2017 |
Role of Ketotifen on metabolic profiles, inflammation and oxidative stress in diabetic rats.
Topics: Animals; Blood Glucose; Body Weight; Diabetes Mellitus, Experimental; Inflammation; Insulin; Insulin Resistance; Interleukin-6; Ketotifen; Lipid Metabolism; Male; Malondialdehyde; Metabolome; Oxidative Stress; Rats; Rats, Sprague-Dawley | 2017 |
Oleuropein improves glucose tolerance and lipid profile in rats with simultaneous renovascular hypertension and type 2 diabetes.
Topics: Animals; Antioxidants; Blood Glucose; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Disease Models, Animal; Glucose Tolerance Test; Hypertension, Renal; Hypertension, Renovascular; Iridoid Glucosides; Iridoids; Lipids; Male; Malondialdehyde; Molecular Structure; Oxidative Stress; Rats; Rats, Sprague-Dawley; Streptozocin; Superoxide Dismutase | 2017 |
Centella asiatica enhances hepatic antioxidant status and regulates hepatic inflammatory cytokines in type 2 diabetic rats.
Topics: Animals; Antioxidants; Centella; Cytokines; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Glutathione; Glutathione Peroxidase; Inflammation; Liver; Male; Malondialdehyde; Oxidative Stress; Plant Extracts; Rats; Rats, Sprague-Dawley; Streptozocin; Triterpenes | 2017 |
Thymoquinone Defeats Diabetes-Induced Testicular Damage in Rats Targeting Antioxidant, Inflammatory and Aromatase Expression.
Topics: Animals; Antioxidants; Aromatase; Benzoquinones; Body Weight; Diabetes Mellitus, Experimental; Glutathione; Male; Malondialdehyde; NF-kappa B; Nitric Oxide; Nitric Oxide Synthase Type II; Oxidative Stress; Protective Agents; Rats; Rats, Wistar; Spermatogenesis; Streptozocin; Superoxide Dismutase; Testis; Up-Regulation | 2017 |
Zanthoxylum alkylamides activate phosphorylated AMPK and ameliorate glycolipid metabolism in the streptozotocin-induced diabetic rats.
Topics: Acetyl-CoA Carboxylase; Adenylate Kinase; Animals; Blood Glucose; Cell Membrane; Diabetes Mellitus, Experimental; Fatty Acids, Nonesterified; Fructosamine; Glucose Transporter Type 4; Glycolipids; Liver; Male; Malondialdehyde; Muscle, Skeletal; Phosphorylation; Phytotherapy; Plant Extracts; Polyunsaturated Alkamides; Rats; RNA, Messenger; Signal Transduction; Triglycerides; Zanthoxylum | 2017 |
Modulatory effect of garcinol in streptozotocin-induced diabetic Wistar rats.
Topics: Animals; Antioxidants; Blood Glucose; Body Weight; Catalase; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Fasting; Glutathione; Glycated Hemoglobin; Glycogen; Homeostasis; Hypoglycemic Agents; Hypolipidemic Agents; Insulin; Insulin-Secreting Cells; Kidney; Liver; Male; Malondialdehyde; Rats; Rats, Wistar; Superoxide Dismutase; Terpenes; Urea | 2017 |
Sitagliptin Attenuates Endothelial Dysfunction of Zucker Diabetic Fatty Rats: Implication of the Antiperoxynitrite and Autophagy.
Topics: Acetylcholine; Animals; Aorta, Thoracic; Autophagy; Diabetes Mellitus, Experimental; Endothelium, Vascular; Human Umbilical Vein Endothelial Cells; Humans; Hypoglycemic Agents; Male; Malondialdehyde; Mesenteric Arteries; Nitric Oxide Synthase Type III; Obesity; Peroxynitrous Acid; Rats; Rats, Zucker; Sitagliptin Phosphate; Superoxide Dismutase; Vasodilation | 2018 |
Spirulina platensis prevents hyperglycemia in rats by modulating gluconeogenesis and apoptosis via modification of oxidative stress and MAPK-pathways.
Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Apoptosis; bcl-2-Associated X Protein; Blood Glucose; Caspase 3; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Gluconeogenesis; Glycated Hemoglobin; Hypoglycemic Agents; Insulin; Liver; Male; Malondialdehyde; Mitogen-Activated Protein Kinases; Oxidative Stress; Pancreas; Pyruvate Carboxylase; Rats; Signal Transduction; Spirulina; Streptozocin; Tumor Necrosis Factor-alpha | 2017 |
Ameliorative effect of omega-3 on spermatogenesis, testicular antioxidant status and preimplantation embryo development in streptozotocin-induced diabetes in rats.
Topics: Animals; Antioxidants; Apoptosis; Blood Glucose; Caspase 3; Diabetes Mellitus, Experimental; DNA Fragmentation; Down-Regulation; Embryonic Development; Fatty Acids, Omega-3; Infertility, Male; Inhibins; Male; Malondialdehyde; Proto-Oncogene Proteins c-bcl-2; Rats; Rats, Sprague-Dawley; Semen Analysis; Spermatogenesis; Spermatozoa; Testis; Testosterone; Up-Regulation | 2017 |
Hypoglycemic effects of a Fructus Mori polysaccharide in vitro and in vivo.
Topics: Animals; Antioxidants; Blood Glucose; Catalase; Diabetes Mellitus, Experimental; Fruit; Glutathione Peroxidase; Humans; Hypoglycemic Agents; Insulin; Male; Malondialdehyde; Mice; Morus; Plant Extracts; Polysaccharides; Superoxide Dismutase | 2017 |
Changes in the Pancreas in Experimental Diabetes and the Effect of Lycopene on These Changes: Proliferating, Apoptotic, and Estrogen Receptor α Positive Cells.
Topics: Animals; Antioxidants; Apoptosis; Blood Glucose; Carotenoids; Cell Proliferation; Diabetes Mellitus, Experimental; Estrogen Receptor alpha; Female; Insulin-Secreting Cells; Ki-67 Antigen; Lycopene; Malondialdehyde; Oxidative Stress; Pancreas; Rats; Rats, Wistar; Streptozocin; Time Factors | 2017 |
(-)-Epigallocatechin-3-gallate attenuates myocardial injury induced by ischemia/reperfusion in diabetic rats and in H9c2 cells under hyperglycemic conditions.
Topics: Animals; Apoptosis; Cardiotonic Agents; Catechin; Diabetes Mellitus, Experimental; Hyperglycemia; Male; Malondialdehyde; Myocardial Infarction; Myocardial Reperfusion Injury; Myocytes, Cardiac; Oxidative Stress; Rats, Sprague-Dawley; Sirtuin 1; Superoxide Dismutase | 2017 |
Modulating effects of omega-3 fatty acids and pioglitazone combination on insulin resistance through toll-like receptor 4 in type 2 diabetes mellitus.
Topics: Animals; Blood Glucose; Cholesterol; Combined Modality Therapy; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Diet, High-Fat; Down-Regulation; Fatty Acids, Omega-3; Insulin Resistance; Male; Malondialdehyde; Pioglitazone; Rats; Rats, Sprague-Dawley; Streptozocin; Toll-Like Receptor 4 | 2018 |
SOCS2 exacerbates myocardial injury induced by ischemia/reperfusion in diabetic mice and H9c2 cells through inhibiting the JAK-STAT-IGF-1 pathway.
Topics: Animals; Caspase 3; Cell Line; Diabetes Mellitus, Experimental; Diet, High-Fat; Endoplasmic Reticulum Chaperone BiP; Gene Expression; Heat-Shock Proteins; Insulin-Like Growth Factor I; Janus Kinase 2; L-Lactate Dehydrogenase; Male; Malondialdehyde; Microarray Analysis; Myocardial Reperfusion Injury; Myocardium; Rats; RNA, Small Interfering; Signal Transduction; STAT5 Transcription Factor; Suppressor of Cytokine Signaling Proteins | 2017 |
Bamboo leaf extract ameliorates cardiac fibrosis possibly via alleviating inflammation, oxidative stress and apoptosis.
Topics: Animals; Apoptosis; Bambusa; Blood Glucose; Body Weight; Cardiomyopathies; Caspase 3; Diabetes Mellitus, Experimental; Fibrosis; Glycated Hemoglobin; Inflammation; Interleukin-6; Malondialdehyde; Myocardium; NF-kappa B; Oxidative Stress; Plant Extracts; Plant Leaves; Rats, Sprague-Dawley; Streptozocin; Superoxide Dismutase; Transforming Growth Factor beta1 | 2017 |
Furan induced ovarian damage in non-diabetic and diabetic rats and cellular protective role of lycopene.
Topics: Animals; Antioxidants; Carotenoids; Catalase; Diabetes Mellitus, Experimental; Female; Furans; Glutathione; Glutathione Peroxidase; Lycopene; Malondialdehyde; Oxidative Stress; Rats; Rats, Wistar; Superoxide Dismutase | 2017 |
d-limonene ameliorates diabetes and its complications in streptozotocin-induced diabetic rats.
Topics: Animals; Aspartate Aminotransferases; Catalase; Citrus; Cyclohexenes; Diabetes Mellitus, Experimental; DNA Damage; Female; Glutathione; Glutathione Peroxidase; Glutathione Reductase; Humans; Limonene; Lipoproteins, HDL; Lipoproteins, LDL; Liver; Male; Malondialdehyde; Oxidative Stress; Plant Extracts; Rats; Rats, Wistar; Superoxide Dismutase; Terpenes | 2017 |
Alteration of oxidative stress and inflammatory cytokines induces apoptosis in diabetic nephropathy.
Topics: Animals; Apoptosis; bcl-2-Associated X Protein; Caspase 3; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Epithelial Cells; Gene Expression Regulation; Glutathione Peroxidase; Interleukin-6; Kidney; Male; Malondialdehyde; Oxidative Stress; Proto-Oncogene Proteins c-bcl-2; Rats; Rats, Sprague-Dawley; Signal Transduction; Streptozocin; Superoxide Dismutase; Transforming Growth Factor beta; Tumor Necrosis Factor-alpha | 2017 |
Acute effects of low-level laser therapy (660 nm) on oxidative stress levels in diabetic rats with skin wounds.
Topics: Animals; Diabetes Mellitus, Experimental; Low-Level Light Therapy; Male; Malondialdehyde; Oxidative Stress; Rats; Rats, Wistar; Reactive Oxygen Species; Skin; Wounds and Injuries | 2017 |
Effect of L-carnitine on diabetes-induced changes of skeletal muscles in rats.
Topics: Animals; Antioxidants; Carnitine; Catalase; Diabetes Mellitus, Experimental; Glucose; Glutathione; Glycated Hemoglobin; Hypoglycemic Agents; Insulin; Insulin Resistance; Male; Malondialdehyde; Muscle Contraction; Muscle Proteins; Muscle, Skeletal; Oxidative Stress; Rats; Rats, Sprague-Dawley; Superoxide Dismutase | 2018 |
A Novel Multi-Epitope Vaccine Based on Urate Transporter 1 Alleviates Streptozotocin-Induced Diabetes by Producing Anti-URAT1 Antibody and an Immunomodulatory Effect in C57BL/6J Mice.
Topics: Animals; Antioxidants; Autoantibodies; Autoantigens; Cytokines; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Epitopes; Glucose; Hyperglycemia; Hyperuricemia; Immunoglobulin G; Immunomodulation; Islets of Langerhans; Malondialdehyde; Mice; Organic Anion Transporters; Superoxide Dismutase; T-Lymphocytes; Uric Acid; Vaccines | 2017 |
The additive effects of atorvastatin and insulin on renal function and renal organic anion transporter 3 function in diabetic rats.
Topics: Animals; Atorvastatin; Diabetes Mellitus, Experimental; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Insulin; Interleukin-6; Kidney; Male; Malondialdehyde; Organic Anion Transporters, Sodium-Independent; Oxidative Stress; Pancreas; Protein Kinase C-alpha; Proto-Oncogene Proteins c-bcl-2; Rats; Rats, Wistar; Superoxide Dismutase | 2017 |
Effect of puerarin on type II diabetes mellitus with orthopaedic footwear.
Topics: Animals; Antioxidants; Blood Glucose; Diabetes Mellitus, Experimental; Diabetic Foot; Diet, Carbohydrate Loading; Diet, High-Fat; Drugs, Chinese Herbal; Insulin; Insulin Resistance; Isoflavones; Malondialdehyde; Orthopedics; Physical Conditioning, Animal; Rats; Streptozocin; Superoxide Dismutase | 2017 |
Curcumin alleviates liver oxidative stress in type 1 diabetic rats.
Topics: Animals; Antioxidants; Biomarkers; Catalase; Curcumin; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Disease Models, Animal; Glutathione Peroxidase; Glycogen; Liver; Male; Malondialdehyde; Oxidative Stress; Rats; Superoxide Dismutase | 2018 |
[Sodium hydrosulfide attenuates myocardial injury through activating thioredoxin system in diabetic rats].
Topics: Animals; Blood Glucose; Carrier Proteins; Cell Cycle Proteins; Cytokines; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Diabetic Cardiomyopathies; Lipid Peroxides; Male; Malondialdehyde; Microscopy, Electron, Transmission; Myocardium; Myocytes, Cardiac; Rats, Sprague-Dawley; Sulfides; Thioredoxins | 2017 |
Effects of separate and concurrent supplementation of Nano-sized clinoptilolite and Nigella sativa on oxidative stress, anti-oxidative parameters and body weight in rats with type 2 diabetes.
Topics: Animals; Antioxidants; Body Weight; Catalase; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Glutathione Peroxidase; Male; Malondialdehyde; Nanoparticles; Nigella sativa; Oxidative Stress; Rats; Rats, Wistar; Streptozocin; Superoxide Dismutase; Zeolites | 2017 |
Crocin potentiates antioxidant defense system and improves oxidative damage in liver tissue in diabetic rats.
Topics: Animals; Antioxidants; Blood Glucose; Carotenoids; Catalase; Diabetes Mellitus, Experimental; Glutathione; Glutathione Peroxidase; Hyperglycemia; Liver; Male; Malondialdehyde; Oxidation-Reduction; Oxidative Stress; Rats; Rats, Wistar; Streptozocin; Superoxide Dismutase | 2018 |
Ameliorative Activity of Ethanol Extract of Artocarpus heterophyllus Stem Bark on Pancreatic β-Cell Dysfunction in Alloxan-Induced Diabetic Rats.
Topics: Alloxan; Animals; Artocarpus; Blood Glucose; Diabetes Mellitus, Experimental; Insulin; Insulin-Secreting Cells; Lipid Peroxidation; Male; Malondialdehyde; Phytotherapy; Plant Bark; Plant Extracts; Rats; Rats, Wistar | 2017 |
Protective effects of the Chinese herbal medicine prescription Zhujing pill on retina of streptozotocin-induced diabetic rats.
Topics: Animals; Antioxidants; Blood-Retinal Barrier; C-Reactive Protein; Diabetes Mellitus, Experimental; Diabetic Retinopathy; Drugs, Chinese Herbal; Glutathione Peroxidase; Intercellular Adhesion Molecule-1; Interleukin-1beta; Interleukin-6; Male; Malondialdehyde; Protective Agents; Rats; Rats, Sprague-Dawley; Retina; Streptozocin; Superoxide Dismutase; Tumor Necrosis Factor-alpha; Vascular Endothelial Growth Factor A | 2018 |
[The influence of nettle and burdock extracts in combination with different diets on dyslipidemia in diabetes mellitus model].
Topics: Animals; Arctium; Blood Glucose; Diabetes Mellitus, Experimental; Dyslipidemias; Glycated Hemoglobin; Male; Malondialdehyde; Mice; Plant Extracts; Urtica dioica | 2015 |
miR-503 Is Involved in the Protective Effect of Phase II Enzyme Inducer (CPDT) in Diabetic Cardiomyopathy via Nrf2/ARE Signaling Pathway.
Topics: Animals; Antioxidants; Carboxylic Ester Hydrolases; Diabetes Mellitus, Experimental; Diabetic Cardiomyopathies; Heme Oxygenase-1; Humans; Malondialdehyde; MicroRNAs; NF-E2-Related Factor 2; Oxidative Stress; Rats; Signal Transduction; Sulfhydryl Compounds; Thiones | 2017 |
Selenium-loaded cellulose film derived from Styela clava tunic accelerates the healing process of cutaneous wounds in streptozotocin-induced diabetic Sprague-Dawley rats.
Topics: Animals; Antioxidants; Bandages; Cellulose; Chordata, Nonvertebrate; Diabetes Mellitus, Experimental; Male; Malondialdehyde; Rats; Rats, Sprague-Dawley; Receptor, Insulin; Regeneration; Selenium; Signal Transduction; Skin; Streptozocin; Tensile Strength; Wound Healing | 2018 |
PPAR-α Agonist Improves Hyperglycemia-Induced Oxidative Stress in Pancreatic Cells by Potentiating Antioxidant Defense System.
Topics: Animals; Antioxidants; Catalase; Diabetes Mellitus, Experimental; Fenofibrate; Glutathione; Hyperglycemia; Male; Malondialdehyde; Nitrates; Oxidative Stress; Pancreas; PPAR alpha; Rats; Superoxide Dismutase | 2018 |
Antidiabetic activities of polysaccharides from Anoectochilus roxburghii and Anoectochilus formosanus in STZ-induced diabetic mice.
Topics: Animals; Antioxidants; Blood Glucose; Body Weight; Diabetes Mellitus, Experimental; Glycogen; Hypoglycemic Agents; Insulin; Kidney; Lipids; Liver; Male; Malondialdehyde; Mice, Inbred ICR; Molecular Weight; Monosaccharides; Orchidaceae; Polysaccharides; Spectroscopy, Fourier Transform Infrared; Streptozocin; Uronic Acids | 2018 |
Effects of cinnamic acid on complications of diabetes
Topics: Animals; Antioxidants; Catalase; Cinnamates; Diabetes Mellitus, Experimental; DNA Damage; Glutathione; Lipids; Liver; Malondialdehyde; Oxidative Stress; Phosphoric Monoester Hydrolases; Phytotherapy; Plant Extracts; Rats, Wistar; Superoxide Dismutase; Transferases | 2018 |
Silymarin ameliorates expression of urotensin II (U-II) and its receptor (UTR) and attenuates toxic oxidative stress in the heart of rats with type 2 diabetes.
Topics: Animals; Antioxidants; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Dose-Response Relationship, Drug; Heart; Lipids; Male; Malondialdehyde; Nitric Oxide; Oxidative Stress; Rats; Rats, Wistar; Reactive Oxygen Species; Receptors, G-Protein-Coupled; Silymarin; Urotensins | 2018 |
Protective effect of melatonin in the diabetic rat retina.
Topics: Animals; Antioxidants; Blood Glucose; Diabetes Mellitus, Experimental; Diabetic Retinopathy; Male; Malondialdehyde; Melatonin; Oxidative Stress; Protective Agents; Rats; Rats, Wistar; Retina; Streptozocin | 2018 |
Cilostazol alleviates streptozotocin-induced testicular injury in rats via PI3K/Akt pathway.
Topics: Animals; Cilostazol; Diabetes Complications; Diabetes Mellitus, Experimental; Glutathione; Heme Oxygenase (Decyclizing); Hyperglycemia; Infertility, Male; Inflammation; Male; Malondialdehyde; Oxygen; Phosphatidylinositol 3-Kinases; Phosphodiesterase 3 Inhibitors; Proto-Oncogene Proteins c-akt; Rats; Rats, Wistar; Real-Time Polymerase Chain Reaction; Sildenafil Citrate; Streptozocin; Superoxide Dismutase; Testis; Tetrazoles | 2018 |
Centella asiatica ameliorates diabetes-induced stress in rat tissues via influences on antioxidants and inflammatory cytokines.
Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Asteraceae; Centella; Cytokines; Diabetes Mellitus, Experimental; Inflammation; Kidney; Male; Malondialdehyde; Oxidants; Oxidative Stress; Plant Extracts; Protective Agents; Rats; Rats, Sprague-Dawley; Triterpenes | 2018 |
Antioxidative Effects of Tempol on Mitochondrial Dysfunction in Diabetic Nephropathy.
Topics: Animals; Antioxidants; Catalase; Cell Survival; Cyclic N-Oxides; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Glutathione Peroxidase; Kidney; Lipid Peroxidation; Male; Malondialdehyde; Mitochondria; Oxidative Stress; Rats, Wistar; Spin Labels; Superoxide Dismutase | 2018 |
Vildagliptin/pioglitazone combination improved the overall glycemic control in type I diabetic rats.
Topics: Adamantane; Animals; Blood Glucose; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Drug Therapy, Combination; Glucagon; Glutathione; Glycated Hemoglobin; Insulin; Male; Malondialdehyde; Nitric Oxide; Nitriles; Pancreas; Pioglitazone; Pyrrolidines; Rats, Sprague-Dawley; Streptozocin; Superoxide Dismutase; Thiazolidinediones; Vildagliptin | 2018 |
Melatonin has a protective effect against lipid peroxidation in the bone tissue of diabetic rats subjected to acute swimming exercise.
Topics: Animals; Biomarkers; Bone and Bones; Diabetes Mellitus, Experimental; Dietary Supplements; Glutathione; Lipid Peroxidation; Male; Malondialdehyde; Melatonin; Oxidation-Reduction; Rats; Swimming | 2018 |
[Effect of naringin on oxidative stress and endoplasmic reticulum stress in diabetic cardiomyopathy].
Topics: Animals; Apoptosis; Cardiotonic Agents; Caspase 12; Diabetes Mellitus, Experimental; Diabetic Cardiomyopathies; Endoplasmic Reticulum Stress; Flavanones; Heat-Shock Proteins; Male; Malondialdehyde; Oxidative Stress; Rats; Rats, Sprague-Dawley; Superoxide Dismutase; Transcription Factor CHOP | 2018 |
Prophylactic mechanisms of Cucumis melo var. flexuosus and Phoenix dactylifera fruit extracts against diabetic cardiomyopathy in streptozotocin induced diabetic rats.
Topics: Animals; Blood Glucose; C-Reactive Protein; Caspase 3; Creatine Kinase, MB Form; Cucumis melo; Diabetes Mellitus, Experimental; Diabetic Cardiomyopathies; DNA Fragmentation; Drug Therapy, Combination; Fruit; Glutathione Peroxidase; Hypoglycemic Agents; Insulin; Male; Malondialdehyde; Myocardium; Phoeniceae; Plant Extracts; Rats; Tumor Necrosis Factor-alpha | 2018 |
Grape seed extract effects on serum amylase levels and immunohistochemical alterations in Streptozotocin-induced diabetic rats.
Topics: Amylases; Animals; Antioxidants; Apoptosis; Caspase 3; Diabetes Mellitus, Experimental; Female; Gene Expression; Grape Seed Extract; Hypoglycemic Agents; Immunohistochemistry; Islets of Langerhans; Malondialdehyde; Oxidative Stress; Rats; Rats, Wistar; Streptozocin | 2018 |
Akkermansia muciniphila can reduce the damage of gluco/lipotoxicity, oxidative stress and inflammation, and normalize intestine microbiota in streptozotocin-induced diabetic rats.
Topics: Animals; Cholesterol, HDL; Diabetes Mellitus, Experimental; Feces; Gastrointestinal Microbiome; Gene Expression Regulation; Glucagon-Like Peptide 1; Glycogen; Hypoglycemic Agents; Inflammation; Intestinal Mucosa; Intestines; Lipopolysaccharides; Liver; Male; Malondialdehyde; Oxidative Stress; Plasminogen Activator Inhibitor 1; Probiotics; Rats; Rats, Sprague-Dawley; Streptozocin; Tumor Necrosis Factor-alpha; Verrucomicrobia | 2018 |
[Nicorandil improves cognitive dysfunction in mice with streptozotocin-induced diabetes].
Topics: Animals; Blood Glucose; Cognitive Dysfunction; Diabetes Mellitus, Experimental; Gastric Inhibitory Polypeptide; Glucagon-Like Peptide 1; Hippocampus; Insulin-Secreting Cells; Malondialdehyde; Mice; Mice, Inbred C57BL; Nicorandil; Streptozocin; Superoxide Dismutase | 2018 |
Effect of melatonin on antioxidant capacity, ınflammation and apoptotic cell death in lung tissue of diabetic rats.
Topics: Animals; Antioxidants; Caspase 3; Catalase; Diabetes Mellitus, Experimental; Glutathione; Immunohistochemistry; Lipid Peroxidation; Lung; Male; Malondialdehyde; Melatonin; Peroxidase; Pyroptosis; Random Allocation; Rats, Sprague-Dawley; Reproducibility of Results; Streptozocin; Superoxide Dismutase; Time Factors | 2018 |
[MECHANISMS OF AFOBAZOLE INFLUENCE ON THE NO PRODUCING ENDOTHELIUM FUNCTION AND INDICATORS OF OXIDATIVE STRESS IN RATS WITH EXPERIMENTAL DIABETES MELLITUS.]
Topics: Animals; Benzimidazoles; Diabetes Mellitus, Experimental; Endothelium, Vascular; Lipid Peroxidation; Male; Malondialdehyde; Morpholines; Nitric Oxide; Nitric Oxide Synthase Type III; Oxidative Stress; Rats; Rats, Wistar | 2016 |
Tanshinone IIA exerts neuroprotective effects on hippocampus-dependent cognitive impairments in diabetic rats by attenuating ER stress-induced apoptosis.
Topics: Abietanes; Animals; Apoptosis; Cognitive Dysfunction; Diabetes Mellitus, Experimental; Disease Models, Animal; Endoplasmic Reticulum Chaperone BiP; Endoplasmic Reticulum Stress; Heat-Shock Proteins; Hippocampus; Male; Malondialdehyde; Maze Learning; Neurons; Neuroprotective Agents; Rats; Rats, Sprague-Dawley; Streptozocin; Superoxide Dismutase; Transcription Factor CHOP | 2018 |
Diabetes escalates knee osteoarthritis in rats: Evidence of adaptive mechanism.
Topics: Alkaline Phosphatase; Animals; Collagen Type I; Collagen Type II; Diabetes Mellitus, Experimental; L-Lactate Dehydrogenase; Male; Malondialdehyde; Osteoarthritis, Knee; Peptides; Rats, Wistar | 2018 |
High sucrose low copper diet in pregnant diabetic rats induces transient oxidative stress, hypoxia, and apoptosis in the offspring's liver.
Topics: Animals; Antioxidants; Apoptosis; Biomarkers; Catalase; Cell Proliferation; Copper; Diabetes Mellitus, Experimental; Diet; Female; Hypoxia; Liver; Malondialdehyde; NF-kappa B; Oxidative Stress; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Sucrose; Superoxide Dismutase; Tyrosine; Weight Gain | 2018 |
Ursodeoxycholic acid suppresses the formation of fructose/streptozotocin-induced diabetic cataract in rats.
Topics: Animals; Antioxidants; Cataract; Diabetes Mellitus, Experimental; Disease Models, Animal; Fructose; Glutathione; Hyperglycemia; Insulin; Lens, Crystalline; Male; Malondialdehyde; Oxidative Stress; Rats; Rats, Wistar; Streptozocin; Ursodeoxycholic Acid | 2018 |
[Impairment of spatial learning and memory and changes of oxidative stress in hippocampus from Type 1 diabetic mice].
Topics: Animals; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Hippocampus; Male; Malondialdehyde; Maze Learning; Memory; Memory Disorders; Mice; Nitric Oxide Synthase Type II; Oxidative Stress; Random Allocation; Spatial Learning; Superoxide Dismutase | 2018 |
Nrf2 protects against diabetic dysfunction of endothelial progenitor cells via regulating cell senescence.
Topics: Animals; Cell Movement; Cells, Cultured; Cellular Senescence; Diabetes Mellitus, Experimental; Endothelial Progenitor Cells; Male; Malondialdehyde; Mice; Mice, Inbred C57BL; NF-E2-Related Factor 2; Nitric Oxide; Oxidative Stress; Reactive Oxygen Species; Superoxide Dismutase; Vascular Endothelial Growth Factor A | 2018 |
[Effects of ursolic acid on liver injury and its possible mechanism in diabetes mellitus mice].
Topics: Alanine Transaminase; Animals; Aspartate Aminotransferases; Blood Glucose; Cholesterol; Diabetes Mellitus, Experimental; Diet, High-Fat; Fatty Liver; Liver; Male; Malondialdehyde; Mice; Mice, Inbred ICR; Random Allocation; Superoxide Dismutase; Triglycerides; Triterpenes; Ursolic Acid | 2018 |
[Intervention effect of trillium tschonoskii maxim extract solution on myocardial injury in diabetic rats].
Topics: Animals; Apoptosis; Diabetes Mellitus, Experimental; Glutathione Peroxidase; Heart; Male; Malondialdehyde; Myocardium; Natriuretic Peptide, Brain; Oxidative Stress; Plant Extracts; Rats; Rats, Sprague-Dawley; Superoxide Dismutase; Trillium; Troponin I | 2016 |
[Protective effect of hydrogen sulfide on kidneys of type 1 diabetic rats].
Topics: Animals; Apoptosis; bcl-2-Associated X Protein; Blood Urea Nitrogen; Caspase 3; Creatinine; Diabetes Mellitus, Experimental; Hydrogen Sulfide; Kidney; Male; Malondialdehyde; Oxidative Stress; Protective Agents; Proto-Oncogene Proteins c-bcl-2; Rats; Rats, Sprague-Dawley; Streptozocin; Superoxide Dismutase | 2016 |
[Intervention effects of oral active AdipoRon on liver oxidative stress in type 2 diabetic mice].
Topics: Animals; Blood Glucose; Catalase; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Hypoglycemic Agents; Liver; Male; Malondialdehyde; Mice; Mice, Inbred C57BL; Oxidative Stress; Piperidines; Receptors, Adiponectin; Superoxide Dismutase | 2017 |
[Effects of aerobic exercise combined with melatonin on osteoporosis of type II diabetic rats].
Topics: Animals; Antioxidants; Bone Density; Calcium; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Female; Glutathione Peroxidase; Malondialdehyde; Melatonin; Osteoporosis; Oxidative Stress; Parathyroid Hormone; Phosphates; Physical Conditioning, Animal; Rats; Rats, Sprague-Dawley; Rats, Wistar; Superoxide Dismutase | 2017 |
Anti-Diabetic and Anti-Nephritic Activities of Grifola frondosa Mycelium Polysaccharides in Diet-Streptozotocin-Induced Diabetic Rats Via Modulation on Oxidative Stress.
Topics: Acetylglucosaminidase; Animals; Blood Glucose; Blood Urea Nitrogen; Catalase; Creatinine; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Diet; Diet, High-Fat; Dose-Response Relationship, Drug; Functional Food; Glutathione Peroxidase; Grifola; Hypoglycemic Agents; Interleukin-2; Interleukin-6; Male; Malondialdehyde; NF-kappa B; Oxidative Stress; Polysaccharides; Rats, Wistar; Reactive Oxygen Species; Streptozocin; Superoxide Dismutase; Tumor Necrosis Factor-alpha | 2019 |
Stability of a type 2 diabetes rat model induced by high-fat diet feeding with low-dose streptozotocin injection.
Topics: Animals; Blood Glucose; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Diet, High-Fat; Insulin; Lipids; Liver; Male; Malondialdehyde; Oxidative Stress; Rats; Rats, Wistar; Streptozocin; Superoxide Dismutase; Uric Acid | 2018 |
Antioxidant, anti-inflammatory and synergistic anti-hyperglycemic effects of Malaysian propolis and metformin in streptozotocin-induced diabetic rats.
Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Blood Glucose; Caspase 3; Diabetes Mellitus, Experimental; Drug Synergism; Glycoside Hydrolase Inhibitors; Hypoglycemic Agents; Insulin; Interleukin-1; Islets of Langerhans; Malaysia; Male; Malondialdehyde; Metformin; NF-kappa B; Proliferating Cell Nuclear Antigen; Propolis; Rats, Sprague-Dawley; Streptozocin | 2018 |
The effects of safranal, a constitute of saffron, and metformin on spatial learning and memory impairments in type-1 diabetic rats: behavioral and hippocampal histopathological and biochemical evaluations.
Topics: Animals; Behavior, Animal; Caspase 3; Cell Count; Crocus; Cyclohexenes; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Hippocampus; Hyperglycemia; Malondialdehyde; Maze Learning; Memory Disorders; Metformin; Neurons; Rats, Wistar; Spatial Learning; Streptozocin; Superoxide Dismutase; Swimming; Task Performance and Analysis; Terpenes; Tumor Necrosis Factor-alpha | 2018 |
Sirtuin 5 overexpression attenuates glucolipotoxicity-induced pancreatic β cells apoptosis and dysfunction.
Topics: Animals; Apoptosis; bcl-2-Associated X Protein; bcl-Associated Death Protein; bcl-X Protein; Caspase 3; Cell Line; Diabetes Mellitus, Experimental; Gene Expression Regulation; Glucose; Humans; Insulin; Insulin-Secreting Cells; Malondialdehyde; Mice; Mitochondria; Palmitic Acid; Proto-Oncogene Proteins c-bcl-2; Rats; Signal Transduction; Sirtuins | 2018 |
Identification of therapeutic effect of glucagon-like peptide 1 in the treatment of STZ-induced diabetes mellitus in rats by restoring the balance of intestinal flora.
Topics: Animals; Antioxidants; Blood Glucose; Catalase; Diabetes Mellitus; Diabetes Mellitus, Experimental; Gastrointestinal Microbiome; Glucagon-Like Peptide 1; Glucose; Humans; Inflammation; Insulin; Malondialdehyde; Mice; Nitric Oxide; Oxidative Stress; Rats | 2018 |
Garlic (
Topics: Animals; Antidepressive Agents; Antioxidants; Anxiety; Brain; Depressive Disorder; Diabetes Mellitus, Experimental; Diazepam; Garlic; Glutathione Peroxidase; Imipramine; Male; Malondialdehyde; Maze Learning; Oxidative Stress; Plant Extracts; Rats; Rats, Wistar; Streptozocin; Stress, Psychological; Superoxide Dismutase; Swimming | 2020 |
Resveratrol ameliorates podocyte damage in diabetic mice via SIRT1/PGC-1α mediated attenuation of mitochondrial oxidative stress.
Topics: Animals; Apoptosis; Cell Line; Diabetes Mellitus, Experimental; Disease Models, Animal; Glucose; Male; Malondialdehyde; Membrane Potential, Mitochondrial; Mice; Mitochondria; Oxidative Stress; Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha; Podocytes; Proteinuria; Reactive Oxygen Species; Resveratrol; Sirtuin 1 | 2019 |
Glycine mitigates renal oxidative stress by suppressing Nox4 expression in rats with streptozotocin-induced diabetes.
Topics: Administration, Oral; Animals; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Gene Expression; Glutathione; Glycine; Glycine Agents; Kidney; Male; Malondialdehyde; NADPH Oxidase 4; Oxidative Stress; Rats, Wistar; RNA, Messenger; Streptozocin | 2018 |
Myocardial Protective Effects of Nicorandil on Rats with Type 2 Diabetic Cardiomyopathy.
Topics: Animals; Blood Glucose; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Diabetic Cardiomyopathies; Disease Models, Animal; Heart; Male; Malondialdehyde; Myocardium; Nicorandil; Rats; Rats, Wistar; Superoxide Dismutase | 2018 |
Preventative effects of resveratrol and estradiol on streptozotocin-induced diabetes in ovariectomized mice and the related mechanisms.
Topics: Animals; Antioxidants; Blood Glucose; Diabetes Mellitus, Experimental; Dose-Response Relationship, Drug; Estradiol; Extracellular Signal-Regulated MAP Kinases; Fasting; Female; Gene Expression Regulation; Glucose Transporter Type 4; Insulin; Insulin Receptor Substrate Proteins; Islets of Langerhans; Malondialdehyde; Mice; Ovariectomy; Phosphoproteins; Resveratrol | 2018 |
The effects of lycopene on alloxan induced diabetic optic neuropathy.
Topics: Alloxan; Animals; Anti-Inflammatory Agents; Antioxidants; Diabetes Mellitus, Experimental; Diabetic Neuropathies; Glutathione; Lycopene; Male; Malondialdehyde; NF-kappa B; Optic Nerve Diseases; Rats, Wistar; Retina; Tumor Necrosis Factor-alpha | 2019 |
Effects of Quercetin on Lipid and Protein Damage in the Liver of Streptozotocin-Induced Experimental Diabetic Rats.
Topics: Animals; Antioxidants; Diabetes Mellitus, Experimental; Lipid Peroxidation; Liver; Male; Malondialdehyde; Oxidative Stress; Plant Extracts; Protein Carbonylation; Quercetin; Rats, Wistar | 2019 |
Effect of Resveratrol, a Dietary-Derived Polyphenol, on the Oxidative Stress and Polyol Pathway in the Lens of Rats with Streptozotocin-Induced Diabetes.
Topics: Animals; Antioxidants; Catalase; Diabetes Complications; Diabetes Mellitus, Experimental; Diet; Glutathione; Glutathione Peroxidase; Lens, Crystalline; Lipid Peroxidation; Male; Malondialdehyde; Oxidative Stress; Phytotherapy; Plant Extracts; Polymers; Polyphenols; Rats, Wistar; Resveratrol; Superoxide Dismutase | 2018 |
Antidiabetic, Antihyperlipidemic, and Antioxidant Activities of Mulberry Lees Fermented Products in Diabetic Mice.
Topics: Animals; Antioxidants; Blood Glucose; Catalase; Cholesterol; Diabetes Mellitus, Experimental; Fermentation; Glutathione Peroxidase; Hypoglycemic Agents; Hypolipidemic Agents; Liver; Male; Malondialdehyde; Mice; Mice, Inbred ICR; Morus; Plant Extracts; Superoxide Dismutase; Thiobarbiturates; Triglycerides | 2018 |
Dexpanthenol reduces diabetic nephropathy and renal oxidative stress in rats.
Topics: Animals; Antioxidants; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Disease Models, Animal; Glutathione; Glutathione Peroxidase; Inflammation; Kidney; Male; Malondialdehyde; Oxidative Stress; Pantothenic Acid; Rats, Wistar; Reactive Oxygen Species | 2019 |
Reduction of cellular stress is essential for Fibroblast growth factor 1 treatment for diabetic nephropathy.
Topics: Animals; Antioxidants; Blood Glucose; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Endoplasmic Reticulum Stress; Fibroblast Growth Factor 1; Fibrosis; Gene Expression Regulation; Humans; Kidney; Kidney Glomerulus; Malondialdehyde; Mice; Oxidative Stress | 2018 |
The pectin-insulin patch application prevents the onset of peripheral neuropathy-like symptoms in streptozotocin-induced diabetic rats.
Topics: Animals; Diabetes Mellitus, Experimental; Disease Models, Animal; Disease Progression; Hand Strength; Insulin; Locomotion; Male; Malondialdehyde; Muscle Strength; Nitric Oxide; Pectins; Peripheral Nervous System Diseases; Rats; Rats, Sprague-Dawley; Streptozocin; Transdermal Patch; Tumor Necrosis Factor-alpha | 2018 |
Preparation and characterization of D. opposita Thunb polysaccharide-zinc inclusion complex and evaluation of anti-diabetic activities.
Topics: Animals; Diabetes Mellitus, Experimental; Dioscorea; Female; Hypoglycemic Agents; Insulin; Liver; Male; Malondialdehyde; Mice; Organometallic Compounds; Oxidative Stress; Polysaccharides; Sugars; Zinc | 2019 |
Genistein attenuates renal fibrosis in streptozotocin‑induced diabetic rats.
Topics: Animals; Blood Urea Nitrogen; Creatinine; Diabetes Mellitus, Experimental; Fibrosis; Genistein; Kidney; Kidney Diseases; Lipid Peroxidation; Male; Malondialdehyde; NAD(P)H Dehydrogenase (Quinone); NF-E2-Related Factor 2; Oxidative Stress; Rats; Rats, Sprague-Dawley; Smad3 Protein; Streptozocin; Superoxide Dismutase; Transforming Growth Factor beta1 | 2019 |
Probucol improves erectile function via Activation of Nrf2 and coordinates the HO-1 / DDAH / PPAR-γ/ eNOS pathways in streptozotocin-induced diabetic rats.
Topics: Amidohydrolases; Animals; Arginine; Blood Glucose; Body Weight; Cyclic GMP; Diabetes Mellitus, Experimental; Erectile Dysfunction; Heme Oxygenase-1; Male; Malondialdehyde; NF-E2-Related Factor 2; Nitric Oxide Synthase Type III; PPAR gamma; Probucol; Rats, Sprague-Dawley; Signal Transduction; Streptozocin; Superoxide Dismutase | 2018 |
Thymoquinone Attenuates Cardiomyopathy in Streptozotocin-Treated Diabetic Rats.
Topics: Animals; Antioxidants; Benzoquinones; Diabetes Mellitus, Experimental; Diabetic Cardiomyopathies; Gene Expression Regulation; Male; Malondialdehyde; Nitric Oxide Synthase Type II; Oxidative Stress; Rats; Rats, Wistar; Superoxide Dismutase | 2018 |
Physicochemical properties of polysaccharides separated from Camellia oleifera Abel seed cake and its hypoglycemic activity on streptozotocin-induced diabetic mice.
Topics: Animals; Antioxidants; Blood Glucose; Camellia; Catalase; Diabetes Mellitus, Experimental; Glucose; Glutathione Peroxidase; Hyperlipidemias; Hypoglycemic Agents; Liquid-Liquid Extraction; Liver; Male; Malondialdehyde; Mannose; Mice; Plant Extracts; Polysaccharides; Rhamnose; Seeds; Streptozocin; Superoxide Dismutase; Xylose | 2019 |
Suppression of Oxygen Radicals Protects Diabetic Endothelium Damage and Tissue Perfusion in a Streptozotocin-Induced Diabetes Rodent Model.
Topics: Animals; Antioxidants; Diabetes Mellitus, Experimental; Diabetic Angiopathies; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Administration Schedule; Endothelium, Vascular; Flow Cytometry; Injections, Intraperitoneal; Male; Malondialdehyde; Nitric Oxide Synthase Type III; Oxidative Stress; Random Allocation; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Reference Values; Superoxide Dismutase; Treatment Outcome | 2019 |
Primary study on the hypoglycemic mechanism of 5rolGLP-HV in STZ-induced type 2 diabetes mellitus mice.
Topics: Animals; Blood Glucose; Cyclic AMP-Dependent Protein Kinases; Diabetes Mellitus, Experimental; Drinking; Drug Evaluation, Preclinical; Eating; Gene Expression Regulation; Glucagon-Like Peptide 1; Glucagon-Like Peptide-1 Receptor; Hirudins; Hypoglycemic Agents; Insulin; Islets of Langerhans; Male; Malondialdehyde; MAP Kinase Kinase Kinases; Mice; Mice, Inbred C57BL; Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins c-akt; Recombinant Proteins; Streptozocin; Superoxide Dismutase | 2018 |
Protein-rich extract of
Topics: AMP-Activated Protein Kinases; Animals; Blood Glucose; Catalase; Complex Mixtures; Diabetes Mellitus, Experimental; Drinking; Eating; Gene Expression Regulation; Glucose Transporter Type 4; Houseflies; Hypoglycemic Agents; Insulin; Insulin-Secreting Cells; Larva; Lipoproteins; Liver; Male; Malondialdehyde; PPAR gamma; Rats; Rats, Sprague-Dawley; Streptozocin; Superoxide Dismutase-1 | 2018 |
Modulating impacts of quercetin/sitagliptin combination on streptozotocin-induced diabetes mellitus in rats.
Topics: Animals; Antioxidants; Biomarkers; Blood Glucose; C-Peptide; Diabetes Mellitus, Experimental; Dipeptidyl-Peptidase IV Inhibitors; Dose-Response Relationship, Drug; Drug Therapy, Combination; Glutathione; Insulin-Secreting Cells; Male; Malondialdehyde; NF-kappa B; Oxidative Stress; Quercetin; Rats, Wistar; Sitagliptin Phosphate; Streptozocin; Superoxide Dismutase | 2019 |
Beneficial effects of Spirogyra Neglecta Extract on antioxidant and anti-inflammatory factors in streptozotocin-induced diabetic rats.
Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Blood Glucose; Cholesterol; Diabetes Mellitus, Experimental; Hypoglycemic Agents; Interleukin-6; Male; Malondialdehyde; Plant Extracts; Rats; Rats, Wistar; Spirogyra; Triglycerides; Tumor Necrosis Factor-alpha | 2018 |
Ethanol Extract of Chinese Propolis Attenuates Early Diabetic Retinopathy by Protecting the Blood-Retinal Barrier in Streptozotocin-Induced Diabetic Rats.
Topics: Animals; Blood Glucose; Blood-Retinal Barrier; Diabetes Mellitus, Experimental; Diabetic Retinopathy; Glycated Hemoglobin; Humans; Male; Malondialdehyde; Occludin; Propolis; Protective Agents; Rats; Rats, Sprague-Dawley; Streptozocin | 2019 |
Diosgenin ameliorates testicular damage in streptozotocin-diabetic rats through attenuation of apoptosis, oxidative stress, and inflammation.
Topics: Animals; Apoptosis; Cytokines; Diabetes Mellitus; Diabetes Mellitus, Experimental; Diosgenin; Disease Models, Animal; Humans; Inflammation; Inflammation Mediators; Male; Malondialdehyde; Oxidative Stress; Rats; Sperm Count; Spermatozoa; Testis; Testosterone | 2019 |
The impact of concomitant administration of vanadium and insulin on endothelial dysfunction markers (PAI-1 and ET-1) in type 1 diabetic rats.
Topics: Animals; Blood Glucose; C-Reactive Protein; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Endothelin-1; Endothelium, Vascular; Insulin; Interleukin-6; Male; Malondialdehyde; Plasminogen Activator Inhibitor 1; Prospective Studies; Rats; Rats, Sprague-Dawley; Superoxide Dismutase; Tumor Necrosis Factor-alpha; Vanadium | 2021 |
Arsenic exposure intensifies glycogen nephrosis in diabetic rats.
Topics: Animals; Antioxidants; Apoptosis; Arsenates; Arsenic; Biomarkers; Catalase; Creatinine; Diabetes Mellitus, Experimental; Glycogen; Hazardous Substances; Kidney; Male; Malondialdehyde; Nephrosis; Oxidative Stress; Rats; Rats, Wistar | 2019 |
Inhibition of HDAC3 Ameliorates Cerebral Ischemia Reperfusion Injury in Diabetic Mice In Vivo and In Vitro.
Topics: Animals; Apoptosis; Cell Hypoxia; Cell Survival; Diabetes Mellitus, Experimental; Disease Models, Animal; Histone Deacetylase Inhibitors; Male; Malondialdehyde; Mice; Neuroprotective Agents; Oxidative Stress; PC12 Cells; Rats; Reactive Oxygen Species; Reperfusion Injury; Signal Transduction; Superoxide Dismutase | 2019 |
Matrine improves diabetic cardiomyopathy through TGF-β-induced protein kinase RNA-like endoplasmic reticulum kinase signaling pathway.
Topics: Alkaloids; Animals; Apoptosis; Diabetes Mellitus, Experimental; Diabetic Cardiomyopathies; eIF-2 Kinase; Endoplasmic Reticulum; Endoplasmic Reticulum Stress; Humans; Malondialdehyde; Matrines; Myocardium; PPAR gamma; Protein Kinases; Quinolizines; Rats; Reactive Oxygen Species; RNA; Signal Transduction; Transforming Growth Factor beta | 2019 |
Protective effect of a polysaccharide from Dipsacus asper Wall on streptozotocin (STZ)-induced diabetic nephropathy in rat.
Topics: Animals; Blood Glucose; Body Weight; Catalase; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Dipsacaceae; Dose-Response Relationship, Drug; Fasting; Glutathione; Glycated Hemoglobin; Glycation End Products, Advanced; Lipids; Male; Malondialdehyde; Monosaccharides; Oxidative Stress; Polysaccharides; Rats; Rats, Wistar; Safety; Streptozocin; Superoxide Dismutase | 2019 |
DIBc, a nanochelating-based nano metal-organic framework, shows anti-diabetic effects in high-fat diet and streptozotocin-induced diabetic rats.
Topics: Animals; Blood Glucose; Diabetes Mellitus, Experimental; Diet, High-Fat; Drinking Behavior; Feeding Behavior; Hemoglobins; Insulin; Insulin Resistance; Iron; Lipids; Liver; Male; Malondialdehyde; Metal-Organic Frameworks; Nanoparticles; Rats, Wistar; Streptozocin; Tumor Necrosis Factor-alpha; Weight Gain | 2019 |
The Role of Heme Oxygenase 1 in the Protective Effect of Caloric Restriction against Diabetic Cardiomyopathy.
Topics: Angiotensin II; Animals; Blood Glucose; Caloric Restriction; Carbazoles; Cardiomegaly; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Diabetic Cardiomyopathies; Heme Oxygenase-1; Male; Malondialdehyde; Mesoporphyrins; Mice; Mice, Inbred C57BL; Myocytes, Cardiac; Obesity; Oxidative Stress; Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha; PPAR gamma; Protoporphyrins; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Signal Transduction; Sirtuin 1 | 2019 |
The effects of Momordica balsamina methanolic extract on haematological function in streptozotocin-induced diabetic rats: Effects on selected markers.
Topics: Animals; Biomarkers; Blood Glucose; Diabetes Mellitus, Experimental; Erythrocyte Membrane; Erythropoietin; Glutathione Peroxidase; Male; Malondialdehyde; Methanol; Momordica; Plant Extracts; Rats, Sprague-Dawley; Streptozocin; Superoxide Dismutase | 2019 |
Sesamin: A promising protective agent against diabetes-associated cognitive decline in rats.
Topics: Animals; Antioxidants; Apoptosis; Cognitive Dysfunction; Diabetes Complications; Diabetes Mellitus, Experimental; Dioxoles; Glutathione Peroxidase; Hippocampus; Insulin; Lignans; Male; Malondialdehyde; Oxidative Stress; Protective Agents; Rats; Rats, Wistar; Reactive Oxygen Species; Superoxide Dismutase | 2019 |
Puerarin prevents cataract development and progression in diabetic rats through Nrf2/HO‑1 signaling.
Topics: Animals; Blood Glucose; Cataract; Diabetes Mellitus, Experimental; Drugs, Chinese Herbal; Gene Expression Regulation; Glutathione; Glutathione Peroxidase; Heme Oxygenase (Decyclizing); Hypoglycemic Agents; Interleukin-1beta; Isoflavones; Male; Malondialdehyde; NF-E2-Related Factor 2; Oxidative Stress; Pueraria; Rats; Rats, Wistar; Signal Transduction; Streptozocin; Vascular Endothelial Growth Factor A | 2019 |
Insulin Suppresses Type 1 Diabetes Mellitus-Induced Ventricular Cardiomyocyte Damage Associated with the Inhibition of Biomarkers of Inflammation and Oxidative Stress in Rats.
Topics: Animals; Biomarkers; Blood Glucose; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Heart Ventricles; Hypoglycemic Agents; Inflammation; Insulin; Male; Malondialdehyde; Myocytes, Cardiac; Oxidative Stress; Rats; Rats, Sprague-Dawley; Streptozocin; Tumor Necrosis Factor-alpha | 2019 |
[Intervention of curcumin and its analogue J7 on oxidative stress injury in testis of type 2 diabetic rats].
Topics: Animals; Blood Glucose; Curcumin; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Male; Malondialdehyde; NF-E2-Related Factor 2; Oxidative Stress; Random Allocation; Rats; Rats, Sprague-Dawley; Signal Transduction; Superoxide Dismutase; Testis | 2019 |
[Effects of aerobic exercise and glutamine on oxidative stress and expression of related factors in type 2 diabetic rats].
Topics: Animals; Blood Glucose; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Glutamine; Leptin; Lipid Metabolism; Lipids; Male; Malondialdehyde; Oxidative Stress; Physical Conditioning, Animal; Random Allocation; Rats; Rats, Sprague-Dawley | 2019 |
Protective effects of resveratrol on hepatic ischemia reperfusion injury in streptozotocin-induced diabetic rats.
Topics: Animals; Blood Glucose; Body Weight; Diabetes Mellitus, Experimental; Glutathione; Liver; Malondialdehyde; Protective Agents; Rats, Sprague-Dawley; Reperfusion Injury; Resveratrol; Streptozocin; Tumor Necrosis Factor-alpha | 2019 |
Nilotinib enhances β-islets integrity and secretory functions in a rat model of STZ-induced diabetes mellitus.
Topics: Animals; Antigens, CD; Antigens, Differentiation, Myelomonocytic; Apoptosis; Blood Glucose; Body Weight; Caspase 3; Catalase; Diabetes Mellitus, Experimental; Disease Models, Animal; Dose-Response Relationship, Drug; Gene Expression Regulation, Enzymologic; Glucagon; Glutathione; Insulin; Insulin-Secreting Cells; Male; Malondialdehyde; Organ Size; Oxidative Stress; Pyrimidines; Rats; Rats, Sprague-Dawley; Superoxide Dismutase | 2019 |
Edaravone protects from retinal injury through NF-κB in diabetic rats.
Topics: Animals; Antioxidants; Diabetes Mellitus, Experimental; Diabetic Retinopathy; Edaravone; Interleukin-6; Male; Malondialdehyde; Rats; Rats, Sprague-Dawley; Signal Transduction; Superoxide Dismutase; Treatment Outcome; Tumor Necrosis Factor-alpha | 2019 |
Nigella sativa and thymoquinone suppress cyclooxygenase-2 and oxidative stress in pancreatic tissue of streptozotocin-induced diabetic rats.
Topics: Analysis of Variance; Animals; Benzoquinones; Cyclooxygenase 2; Diabetes Mellitus, Experimental; Gene Expression; Intercellular Adhesion Molecule-1; Lipid Peroxidation; Male; Malondialdehyde; Nigella sativa; Oxidative Stress; Pancreas; Plant Extracts; Rats; Rats, Sprague-Dawley; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Superoxide Dismutase | 2013 |
Iron chelator alleviates tubulointerstitial fibrosis in diabetic nephropathy rats by inhibiting the expression of tenascinC and other correlation factors.
Topics: Animals; Deferiprone; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Iron Chelating Agents; Kidney; Male; Malondialdehyde; Pyridones; Rats; Rats, Wistar; Superoxide Dismutase; Tenascin | 2013 |
Decreased renal organic anion transporter 3 expression in type 1 diabetic rats.
Topics: Animals; Blood Glucose; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Estrone; Kidney Cortex; Male; Malondialdehyde; Organic Anion Transporters, Sodium-Independent; Protein Kinase C-alpha; Rats; Rats, Wistar; Reactive Oxygen Species; Tetradecanoylphorbol Acetate; Transcription Factor RelA; Triglycerides | 2014 |
Advanced glycation end products accelerate rat vascular calcification through RAGE/oxidative stress.
Topics: Alkaline Phosphatase; Animals; Aorta, Thoracic; Aortic Diseases; Biomarkers; Blood Glucose; Cells, Cultured; Cholecalciferol; Diabetes Mellitus, Experimental; Glycation End Products, Advanced; Insulin; Lipids; Male; Malondialdehyde; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; NADH, NADPH Oxidoreductases; NADPH Oxidase 1; Nicotine; Oxidative Stress; Rats; Rats, Sprague-Dawley; Rats, Wistar; Receptor for Advanced Glycation End Products; Receptors, Immunologic; Serum Albumin, Bovine; Signal Transduction; Streptozocin; Superoxide Dismutase; Superoxides; Vascular Calcification | 2013 |
Activation of ALDH2 with ethanol attenuates diabetes induced myocardial injury in rats.
Topics: Aldehyde Dehydrogenase; Aldehyde Dehydrogenase, Mitochondrial; Animals; Blood Glucose; Diabetes Mellitus, Experimental; Erythrocytes; Ethanol; Fasting; Glycated Hemoglobin; Heart Diseases; Male; Malondialdehyde; Microscopy, Electron, Transmission; Mitochondrial Proteins; Myocardium; Rats; Rats, Sprague-Dawley; RNA, Messenger; Superoxide Dismutase | 2013 |
Thyroid hormones-mediated effects of insulin on antioxidant enzymes from diabetic rat hearts.
Topics: Animals; Antioxidants; Catalase; Diabetes Mellitus, Experimental; Glutathione Peroxidase; Insulin; Male; Malondialdehyde; Myocardium; Rats; Superoxide Dismutase; Thyroid Hormones; Thyroidectomy | 2013 |
Bradykinin B₁ antagonism inhibits oxidative stress and restores Na+K+ ATPase activity in diabetic rat peripheral nervous system.
Topics: Animals; Bradykinin; Bradykinin B1 Receptor Antagonists; Diabetes Mellitus, Experimental; Diabetic Neuropathies; Glutathione Reductase; Male; Malondialdehyde; Oxidative Stress; Peripheral Nervous System; Rats; Rats, Wistar; Sciatic Nerve; Sodium-Potassium-Exchanging ATPase; Superoxide Dismutase | 2013 |
Suppression of methylglyoxal hyperactivity by mangiferin can prevent diabetes-associated cognitive decline in rats.
Topics: Animals; Behavior, Animal; Cognition Disorders; Diabetes Mellitus, Experimental; Dose-Response Relationship, Drug; Glutathione; Glycation End Products, Advanced; Hippocampus; Inflammation; Male; Malondialdehyde; Maze Learning; Oxidative Stress; Pyruvaldehyde; Rats; Rats, Sprague-Dawley; Streptozocin; Superoxide Dismutase; Xanthones | 2013 |
Evaluation of hypoglycemic and antioxidative effects of synthesized peptide MC62.
Topics: Amino Acid Sequence; Animals; Blood Glucose; Body Weight; Diabetes Mellitus, Experimental; Glutathione; Glutathione Peroxidase; Glycated Hemoglobin; Hypoglycemic Agents; Islets of Langerhans; Male; Malondialdehyde; Mice; Molecular Sequence Data; Oxidative Stress; Peptides; Streptozocin; Superoxide Dismutase | 2013 |
The protective effects of α-lipoic acid on kidneys in type 2 diabetic Goto-Kakisaki rats via reducing oxidative stress.
Topics: Animals; Blood Glucose; Body Weight; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Glutathione; Kidney; Male; Malondialdehyde; NADPH Oxidases; NF-kappa B; Organ Size; Oxidative Stress; Protective Agents; Proteinuria; Rats, Wistar; Superoxide Dismutase; Thioctic Acid | 2013 |
Brain effect of insulin and clonazepam in diabetic rats under depressive-like behavior.
Topics: Animals; Behavior, Animal; Brain; Clonazepam; Depression; Diabetes Mellitus, Experimental; DNA Damage; GABA Modulators; Hypoglycemic Agents; Insulin; Male; Malondialdehyde; Oxidative Stress; Rats; Rats, Wistar | 2013 |
Blocking type I interferon signaling rescues lymphocytes from oxidative stress, exhaustion, and apoptosis in a streptozotocin-induced mouse model of type I diabetes.
Topics: Animals; Apoptosis; Cell Proliferation; Cytokines; Diabetes Mellitus, Experimental; Disease Models, Animal; I-kappa B Proteins; Interferon Type I; Lymphocytes; Malondialdehyde; Mice; NF-KappaB Inhibitor alpha; Oxidative Stress; Programmed Cell Death 1 Receptor; Proto-Oncogene Proteins c-akt; Reactive Oxygen Species; Receptor, Interferon alpha-beta; Signal Transduction; STAT1 Transcription Factor; STAT2 Transcription Factor | 2013 |
Protective effect of the polysaccharide from Ophiopogon japonicus on streptozotocin-induced diabetic rats.
Topics: Alanine Transaminase; Animals; Aspartate Aminotransferases; Blood Glucose; Connective Tissue Growth Factor; Diabetes Mellitus, Experimental; Drugs, Chinese Herbal; Glutathione Peroxidase; Hypoglycemic Agents; Kidney; Lipids; Liver; Male; Malondialdehyde; Ophiopogon; Oxidative Stress; Plant Roots; Polysaccharides; Rats; Rats, Sprague-Dawley; Streptozocin; Superoxide Dismutase; Transforming Growth Factor beta1 | 2013 |
Anti-diabetic effect of ramulus mori polysaccharides, isolated from Morus alba L., on STZ-diabetic mice through blocking inflammatory response and attenuating oxidative stress.
Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Cyclooxygenase 2; Cytokines; Diabetes Mellitus, Experimental; Glutathione Reductase; Hypoglycemic Agents; Insulin; Male; Malondialdehyde; Mice; Morus; Oxidative Stress; Pancreas; Phytotherapy; Plant Extracts; Polysaccharides; Superoxide Dismutase | 2013 |
In vitro and in vivo anti-diabetic activity of Swertia kouitchensis extract.
Topics: alpha-Amylases; alpha-Glucosidases; Animals; Blood Glucose; Cell Line, Tumor; Diabetes Mellitus, Experimental; Female; Glucokinase; Glucose Tolerance Test; Glucose-6-Phosphatase; Glycogen; Hypoglycemic Agents; Insulin; Insulin Secretion; Lipids; Liver; Male; Malondialdehyde; Mice; Mice, Inbred BALB C; Phytotherapy; Plant Extracts; Superoxide Dismutase; Swertia | 2013 |
Adverse cardiac responses to alpha-lipoic acid in a rat-diabetic model: possible mechanisms?
Topics: Animals; Cholesterol, HDL; Cholesterol, LDL; Diabetes Mellitus, Experimental; Glycation End Products, Advanced; Heart Failure; Male; Malondialdehyde; Myocardium; NADPH Oxidases; Oxidants; Rats; Rats, Wistar; Reactive Oxygen Species; Streptozocin; Thioctic Acid; Triglycerides; Troponin I; Vascular Endothelial Growth Factor A | 2013 |
[Effects of pomegranate flowers polyphenols on liver PON expression of diabetes combining non-alcoholic fat liver diseases rats].
Topics: Alanine Transaminase; Animals; Aryldialkylphosphatase; Aspartate Aminotransferases; Blood Glucose; Diabetes Mellitus, Experimental; Fatty Liver; Flowers; Insulin; Liver; Lythraceae; Male; Malondialdehyde; Non-alcoholic Fatty Liver Disease; Plants, Medicinal; Polyphenols; Random Allocation; Rats; Rats, Sprague-Dawley; RNA, Messenger; Superoxide Dismutase | 2013 |
Antihyperlipidaemic and antioxidant effect of the total flavonoids in Selaginella tamariscina (Beauv.) Spring in diabetic mice.
Topics: Animals; Antioxidants; Blood Glucose; Diabetes Mellitus, Experimental; Diet, High-Fat; Fatty Acids, Nonesterified; Fatty Liver; Flavonoids; Hypoglycemic Agents; Hypolipidemic Agents; Insulin; Insulin Resistance; Lipids; Liver; Male; Malondialdehyde; Mice; Mice, Inbred Strains; Nicotinamide Phosphoribosyltransferase; Nitric Oxide; Nitric Oxide Synthase Type II; Phytotherapy; Plant Extracts; Selaginellaceae | 2013 |
Cerebroprotective effect of resveratrol through antioxidant and anti-inflammatory effects in diabetic rats.
Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Brain; Catalase; Cerebral Infarction; Cytokines; Diabetes Mellitus, Experimental; Malondialdehyde; Neuroprotective Agents; Oxidative Stress; Peroxidase; Rats; Rats, Wistar; Resveratrol; Stilbenes; Superoxide Dismutase | 2013 |
Taurine attenuates oxidative stress and alleviates cardiac failure in type I diabetic rats.
Topics: Animals; Blood Glucose; Blotting, Western; Body Weight; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Diabetic Cardiomyopathies; Heart Failure; Heme Oxygenase-1; Male; Malondialdehyde; Organ Size; Oxidation-Reduction; Oxidative Stress; Phosphorylation; Proto-Oncogene Proteins c-akt; Rats; Rats, Sprague-Dawley; Superoxide Dismutase; Taurine | 2013 |
The protective effects of beta-casomorphin-7 against glucose -induced renal oxidative stress in vivo and vitro.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Blood Glucose; Cell Line; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Endorphins; Epithelial Cells; Glucagon; Glutathione Peroxidase; Hydrogen Peroxide; Insulin; Isoenzymes; Kidney; Losartan; Male; Malondialdehyde; Oxidative Stress; Peptide Fragments; Peptidyl-Dipeptidase A; Rats; Rats, Sprague-Dawley; Superoxide Dismutase | 2013 |
Testosterone promotes glucose intolerance, lipid disorder and oxidative stress in type 1 diabetic rats.
Topics: Animals; Blood Glucose; Catalase; Diabetes Mellitus, Experimental; Glucose Intolerance; Glucose Tolerance Test; Glutathione; Insulin; Lipids; Male; Malondialdehyde; Orchiectomy; Oxidative Stress; Rats; Superoxide Dismutase; Testosterone | 2014 |
Pivotal role of oxidative stress in tumor metastasis under diabetic conditions in mice.
Topics: Animals; Blood Glucose; Catalase; Cell Proliferation; Diabetes Mellitus, Experimental; Hydrogen Peroxide; Liver; Liver Neoplasms; Lung; Lung Neoplasms; Male; Malondialdehyde; Melanoma, Experimental; Mice; Mice, Inbred C57BL; Oxidative Stress; Polyethylene Glycols | 2013 |
Protective effect of short-term genistein supplementation on the early stage in diabetes-induced renal damage.
Topics: Animals; Antioxidants; Blood Urea Nitrogen; C-Reactive Protein; Chemokine CCL2; Creatinine; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Female; Genistein; Kidney; Lipid Peroxidation; Malondialdehyde; Mice; Mice, Inbred ICR; Oxidative Stress; Protein Kinase C; Protein Kinase C beta; Transcription Factor RelA; Tumor Necrosis Factor-alpha | 2013 |
Vasculoprotective effects of combined endothelial progenitor cells and mesenchymal stem cells in diabetic wound care: their potential role in decreasing wound-oxidative stress.
Topics: Animals; Blood Glucose; Body Weight; Capillaries; Diabetes Mellitus, Experimental; Endothelial Cells; Fibrin; Humans; Male; Malondialdehyde; Mesenchymal Stem Cells; Mice; Mice, Inbred BALB C; Mice, Nude; Neovascularization, Physiologic; Neutrophil Infiltration; Oxidative Stress; Stem Cell Transplantation; Vascular Endothelial Growth Factor A; Wound Healing | 2013 |
The combined effect of metformin and L-cysteine on inflammation, oxidative stress and insulin resistance in streptozotocin-induced type 2 diabetes in rats.
Topics: Animals; Body Weight; C-Reactive Protein; Caspase 3; Chemokine CCL2; Cysteine; Cytochromes c; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Drug Interactions; Fatty Acids, Nonesterified; Glutathione; Inflammation; Insulin Resistance; Liver; Male; Malondialdehyde; Metformin; Nitrates; Nitrites; Oxidative Stress; Rats; Rats, Wistar | 2013 |
Antioxidant and antidiabetic profiles of two African medicinal plants: Picralima nitida (Apocynaceae) and Sonchus oleraceus (Asteraceae).
Topics: Africa; Animals; Antioxidants; Apocynaceae; Biphenyl Compounds; Blood Glucose; Catalase; Diabetes Mellitus, Experimental; Hydrogen Peroxide; Hyperglycemia; Hypoglycemic Agents; Male; Malondialdehyde; Mice; Oxidative Stress; Phytotherapy; Picrates; Plant Extracts; Plant Structures; Polyphenols; Sonchus | 2013 |
The role of Acacia Arabica extract as an antidiabetic, antihyperlipidemic, and antioxidant in streptozotocin-induced diabetic rats.
Topics: Acacia; Animals; Antioxidants; Blood Glucose; Cholesterol; Cholesterol, HDL; Cholesterol, LDL; Diabetes Mellitus, Experimental; Female; Hypoglycemic Agents; Hypolipidemic Agents; Insulin; Malondialdehyde; Phytotherapy; Plant Extracts; Rats; Streptozocin; Triglycerides; Ubiquinone | 2013 |
Antioxidant and renoprotective effects of Spirogyra neglecta (Hassall) Kützing extract in experimental type 2 diabetic rats.
Topics: Animals; Antioxidants; Biological Transport; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Estrone; Gene Expression Regulation; Insulin; Kidney; Kidney Cortex; Male; Malondialdehyde; Organic Anion Transporters, Sodium-Independent; p-Aminohippuric Acid; Phytotherapy; Plant Extracts; Protective Agents; Protein Kinases; Rats; Rats, Wistar; RNA, Messenger; Spirogyra; Staining and Labeling; Stress, Physiological | 2013 |
Mangiferin from Salacia chinensis prevents oxidative stress and protects pancreatic β-cells in streptozotocin-induced diabetic rats.
Topics: Animals; Antioxidants; Blood Glucose; Diabetes Mellitus, Experimental; Humans; Insulin; Insulin-Secreting Cells; Islets of Langerhans; Male; Malondialdehyde; Oxidative Stress; Plant Extracts; Protective Agents; Rats; Rats, Wistar; Salacia; Xanthones | 2013 |
Curcumin improves expression of ghrelin through attenuating oxidative stress in gastric tissues of streptozotocin-induced diabetic gastroparesis rats.
Topics: Animals; Antioxidants; Blood Glucose; Curcumin; Diabetes Mellitus, Experimental; Gastric Emptying; Gastric Mucosa; Gastroparesis; Gene Expression Regulation; Ghrelin; Glutathione; Male; Malondialdehyde; Oxidative Stress; Rats; Rats, Wistar; RNA, Messenger; Stomach | 2013 |
Antidiabetic effects of Swertia macrosperma extracts in diabetic rats.
Topics: Animals; Antioxidants; Catalase; Diabetes Mellitus, Experimental; Glucokinase; Glucose; Glucose-6-Phosphatase; Glutathione Peroxidase; Glycated Hemoglobin; Glycogen; Hep G2 Cells; Humans; Hypoglycemic Agents; Insulin; Lipids; Liver; Male; Malondialdehyde; Pancreas; Phytotherapy; Plant Extracts; Rats; Rats, Wistar; Superoxide Dismutase; Swertia | 2013 |
Antidiabetic and antioxidant effects of Annona muricata (Annonaceae), aqueous extract on streptozotocin-induced diabetic rats.
Topics: Alanine Transaminase; Animals; Annona; Antioxidants; Aspartate Aminotransferases; Blood Glucose; Catalase; Creatinine; Diabetes Mellitus, Experimental; Hypoglycemic Agents; Lipids; Male; Malondialdehyde; Nitrites; Phytotherapy; Plant Extracts; Plant Leaves; Rats; Rats, Wistar; Superoxide Dismutase; Toxicity Tests, Acute; Toxicity Tests, Subacute; Toxicity Tests, Subchronic | 2014 |
Efficacy of biodegradable curcumin nanoparticles in delaying cataract in diabetic rat model.
Topics: Aldehyde Reductase; Animals; Antioxidants; Biocompatible Materials; Biodegradation, Environmental; Blood Glucose; Body Weight; Cataract; Crystallins; Curcumin; Diabetes Mellitus, Experimental; Disease Models, Animal; Disease Progression; Feeding Behavior; Insulin; Lactic Acid; Lens, Crystalline; Malondialdehyde; Nanoparticles; Oxidative Stress; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Protein Carbonylation; Rats; Sorbitol; Streptozocin; Superoxide Dismutase; Treatment Outcome | 2013 |
[Study on the effect of ursolic acid (UA) on the myocardial fibrosis of experimental diabetic mice].
Topics: Animals; Blood Glucose; Collagen; Diabetes Mellitus, Experimental; Fibrosis; Hydroxyproline; Male; Malondialdehyde; Mice; Mice, Inbred Strains; Myocardium; Oxidative Stress; Superoxide Dismutase; Transforming Growth Factor beta1; Triterpenes; Ursolic Acid | 2013 |
Antihyperglycemic, antihyperlipidemic and antioxidant effects of ethanol and aqueous extracts of Cyclocarya paliurus leaves in type 2 diabetic rats.
Topics: Animals; Antioxidants; Blood Glucose; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Diet, High-Fat; Glutathione Peroxidase; Hyperlipidemias; Hypoglycemic Agents; Hypolipidemic Agents; Insulin; Juglandaceae; Lipids; Male; Malondialdehyde; Phytotherapy; Plant Extracts; Plant Leaves; Rats; Rats, Sprague-Dawley; Superoxide Dismutase | 2013 |
The protective effect of aqueous extracts of roselle (Hibiscus sabdariffa L. UKMR-2) against red blood cell membrane oxidative stress in rats with streptozotocin-induced diabetes.
Topics: Animals; Antioxidants; Body Weight; Diabetes Mellitus, Experimental; Erythrocyte Membrane; Hibiscus; Male; Malondialdehyde; Oxidative Stress; Plant Extracts; Rats; Rats, Sprague-Dawley; Reproducibility of Results; Streptozocin; Superoxide Dismutase; Time Factors; Treatment Outcome | 2013 |
Investigation of the in vivo antioxidative activity of Cynara scolymus (artichoke) leaf extract in the streptozotocin-induced diabetic rat.
Topics: 8-Hydroxy-2'-Deoxyguanosine; Animals; Antioxidants; Body Weight; Cynara scolymus; Deoxyguanosine; Diabetes Mellitus, Experimental; Dietary Supplements; Glutathione; Malondialdehyde; Oxidative Stress; Plant Extracts; Plant Leaves; Rats; Rats, Wistar; Streptozocin | 2014 |
Expression of hepatic antioxidant enzymes in non-obese type-2 diabetic Goto-Kakizaki rats.
Topics: Animals; Antioxidants; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Free Radical Scavengers; Gene Expression; Glutathione Transferase; Isoenzymes; Lipid Peroxidation; Liver; Male; Malondialdehyde; Oxidative Stress; Peroxiredoxins; Rats; Rats, Inbred Strains; Species Specificity | 2014 |
Neuroprotective effects of folic acid on experimental diabetic peripheral neuropathy.
Topics: Animals; Diabetes Mellitus, Experimental; Diabetic Neuropathies; Disease Models, Animal; Female; Folic Acid; Lipid Peroxidation; Malondialdehyde; Nerve Growth Factors; Neuroprotective Agents; Rats; Rats, Sprague-Dawley; Sciatic Nerve | 2016 |
Antioxidant effects of maslinic acid in livers, hearts and kidneys of streptozotocin-induced diabetic rats: effects on kidney function.
Topics: Animals; Antioxidants; Blood Glucose; Body Weight; Diabetes Mellitus, Experimental; Drinking; Glucose Transport Proteins, Facilitative; Glycogen; Heart; Insulin; Insulin Secretion; Kidney Tubules, Proximal; Lipid Peroxidation; Liver; Malondialdehyde; Myocardium; Oxidative Stress; Rats; Rats, Wistar; Sodium; Triterpenes; Water-Electrolyte Balance | 2014 |
Lavender (Lavandula stoechas L.) essential oils attenuate hyperglycemia and protect against oxidative stress in alloxan-induced diabetic rats.
Topics: Alloxan; Animals; Antioxidants; Biphenyl Compounds; Diabetes Mellitus, Experimental; Gas Chromatography-Mass Spectrometry; Hyperglycemia; Hypoglycemic Agents; Injections, Intraperitoneal; Kidney; Lavandula; Lipid Peroxidation; Liver; Male; Malondialdehyde; Norbornanes; Oils, Volatile; Oxidative Stress; Picrates; Plant Components, Aerial; Rats; Rats, Wistar; Terpenes | 2013 |
Ice plant (Mesembryanthemum crystallinum) improves hyperglycaemia and memory impairments in a Wistar rat model of streptozotocin-induced diabetes.
Topics: Acetylcholinesterase; Animals; Avoidance Learning; Blood Glucose; Brain; Cholinesterase Inhibitors; Diabetes Mellitus, Experimental; Hyperglycemia; Hypoglycemic Agents; Inositol; Male; Malondialdehyde; Memory Disorders; Memory, Short-Term; Mesembryanthemum; Mice; Oxidative Stress; Phytotherapy; Plant Extracts; Rats, Wistar; Superoxide Dismutase | 2014 |
[Protective effect of total flavonoids of herba epimedii on testis degeneration in diabetic mice].
Topics: Animals; Blood Glucose; Diabetes Mellitus, Experimental; Drugs, Chinese Herbal; Flavonoids; Male; Malondialdehyde; Matrix Metalloproteinase 9; Mice; Mice, Inbred ICR; Superoxide Dismutase; Testis; Testosterone | 2013 |
Effects of systemic chlorogenic acid on random-pattern dorsal skin flap survival in diabetic rats.
Topics: Animals; Antioxidants; Capillaries; Chlorogenic Acid; Dermatologic Surgical Procedures; Diabetes Mellitus, Experimental; Glutathione; Male; Malondialdehyde; Nitric Oxide; Plant Extracts; Rats; Rats, Wistar; Reference Values; Skin; Superoxide Dismutase; Surgical Flaps; Vascular Endothelial Growth Factor A | 2014 |
Emblica officinalis improves glycemic status and oxidative stress in STZ induced type 2 diabetic model rats.
Topics: Alanine Transaminase; Analysis of Variance; Animals; Antioxidants; Blood Glucose; Creatinine; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Glucose; Glutathione; Hypoglycemic Agents; Insulin; Male; Malondialdehyde; Oxidative Stress; Phyllanthus emblica; Plant Extracts; Rats; Rats, Long-Evans | 2014 |
Oxymatrine attenuates diabetes-associated cognitive deficits in rats.
Topics: Alkaloids; Animals; Anti-Inflammatory Agents; Antioxidants; Behavior, Animal; Blood Glucose; Body Weight; Caspase 3; Cerebral Cortex; Cognition; Cognition Disorders; Diabetes Mellitus, Experimental; Dose-Response Relationship, Drug; Glutathione; Hippocampus; Inflammation Mediators; Interleukin-1beta; Male; Malondialdehyde; Maze Learning; Memory; Motor Activity; Oxidative Stress; Quinolizines; Rats, Wistar; Streptozocin; Superoxide Dismutase; Time Factors; Transcription Factor RelA; Tumor Necrosis Factor-alpha | 2014 |
Astragalus polysaccharide suppresses skeletal muscle myostatin expression in diabetes: involvement of ROS-ERK and NF-κB pathways.
Topics: Animals; Blood Glucose; Body Weight; Cell Line; Diabetes Mellitus, Experimental; Extracellular Signal-Regulated MAP Kinases; Fatty Acids; Gene Expression Regulation; Insulin Resistance; Male; Malondialdehyde; MAP Kinase Signaling System; Mice; Mice, Inbred C57BL; Muscle, Skeletal; Myostatin; NF-kappa B; Palmitic Acid; Polysaccharides; Reactive Oxygen Species; RNA, Messenger | 2013 |
Panax notoginseng saponins improve erectile function through attenuation of oxidative stress, restoration of Akt activity and protection of endothelial and smooth muscle cells in diabetic rats with erectile dysfunction.
Topics: Animals; Antioxidants; Diabetes Mellitus, Experimental; Dose-Response Relationship, Drug; Endothelial Cells; Erectile Dysfunction; Glutathione; Humans; Immunohistochemistry; Male; Malondialdehyde; Microscopy, Electron; Myocytes, Smooth Muscle; Oxidative Stress; Panax notoginseng; Penis; Plant Extracts; Proto-Oncogene Proteins c-akt; Rats; Rats, Sprague-Dawley; Saponins; Superoxide Dismutase | 2014 |
Total triterpene acids, isolated from Corni Fructus, ameliorate progression of renal damage in streptozotocin-induced diabetic rats.
Topics: Animals; Blood Glucose; Blood Urea Nitrogen; Blotting, Western; Body Weight; Catalase; Cornus; Creatinine; Diabetes Mellitus, Experimental; Disease Progression; Glutathione Peroxidase; Hypertrophy; Kidney; Kidney Function Tests; Male; Malondialdehyde; Rats, Sprague-Dawley; Streptozocin; Superoxide Dismutase; Transforming Growth Factor beta1; Triterpenes | 2014 |
Dietary supplementation with a low dose of (-)-epigallocatechin-3-gallate reduces pro-inflammatory responses in peripheral leukocytes of non-obese type 2 diabetic GK rats.
Topics: 8-Hydroxy-2'-Deoxyguanosine; Analysis of Variance; Animals; Catechin; Chemokines; Corn Oil; Cytokines; Deoxyguanosine; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Diet; Diet, High-Fat; Dietary Fats; Dietary Supplements; Disease Models, Animal; Inflammation; Leukocytes; Male; Malondialdehyde; Oxidative Stress; Polymerase Chain Reaction; Rats; Rats, Wistar | 2013 |
Protective effects of polysaccharides from Lilium lancifolium on streptozotocin-induced diabetic mice.
Topics: Animals; Antioxidants; Blood Glucose; Body Weight; Diabetes Mellitus, Experimental; Kidney; Lilium; Liver; Male; Malondialdehyde; Mice; Organ Size; Pancreas; Polysaccharides | 2014 |
Antidiabetic effect of flavonoids from Malus toringoides (Rehd.) Hughes leaves in diabetic mice and rats.
Topics: Animals; Behavior, Animal; Blood Glucose; Body Weight; C-Peptide; Diabetes Mellitus, Experimental; Female; Flavonoids; Glycated Hemoglobin; Hypoglycemic Agents; Insulin; Liver; Male; Malondialdehyde; Malus; Mice; Phytotherapy; Plant Leaves; Rats, Sprague-Dawley; Superoxide Dismutase | 2014 |
Prevention of arterial stiffening by using low-dose atorvastatin in diabetes is associated with decreased malondialdehyde.
Topics: Animals; Arginine; Atorvastatin; Blood Glucose; Blood Pressure; Body Weight; C-Reactive Protein; Cholesterol; Diabetes Mellitus, Experimental; Dose-Response Relationship, Drug; Fatty Acids; Glycation End Products, Advanced; Hemodynamics; Heptanoic Acids; Lysine; Male; Malondialdehyde; Organ Size; Pyrroles; Rats, Wistar; Streptozocin; Vascular Stiffness | 2014 |
Effects of puerarin in STZ-induced diabetic rats by oxidative stress and the TGF-β1/Smad2 pathway.
Topics: Animals; Blood Glucose; Diabetes Mellitus, Experimental; Drugs, Chinese Herbal; Humans; Interferon-gamma; Interleukin-4; Isoflavones; Male; Malondialdehyde; Oxidative Stress; Pueraria; Rats; Rats, Wistar; Signal Transduction; Smad2 Protein; Transforming Growth Factor beta1 | 2014 |
Therapeutic effects of stem cell on hyperglycemia, hyperlipidemia, and oxidative stress in alloxan-treated rats.
Topics: Alloxan; Animals; Blood Glucose; Diabetes Mellitus, Experimental; Female; Flow Cytometry; Glutathione; Glycogen; Hyperglycemia; Hyperlipidemias; Insulin; Lipids; Liver; Male; Malondialdehyde; Mesenchymal Stem Cell Transplantation; Mesenchymal Stem Cells; N-Acetylneuraminic Acid; Nitric Oxide; Oxidative Stress; Pancreas; Rats, Wistar; Vitamin E | 2014 |
Cell-based regenerative strategies for treatment of diabetic skin wounds, a comparative study between human umbilical cord blood-mononuclear cells and calves' blood haemodialysate.
Topics: Actihaemyl; Animals; Blood Glucose; Blood Platelets; Catalase; Cattle; Diabetes Mellitus, Experimental; Female; Fetal Blood; Hemodialysis Solutions; Humans; Leukocytes, Mononuclear; Male; Malondialdehyde; Nitric Oxide; Rats; Rats, Wistar; Skin; Tissue Extracts; Wound Healing | 2014 |
Nicorandil attenuates endothelial VCAM-1 expression via thioredoxin production in diabetic rats induced by streptozotocin.
Topics: Animals; Antihypertensive Agents; Blood Glucose; Body Weight; Diabetes Mellitus, Experimental; Endothelial Cells; Fasting; Gene Expression Regulation; Immunohistochemistry; Male; Malondialdehyde; Nicorandil; Rats; Streptozocin; Superoxide Dismutase; Thioredoxins; Vascular Cell Adhesion Molecule-1 | 2014 |
Effects of vanadium (III, IV, V)-chlorodipicolinate on glycolysis and antioxidant status in the liver of STZ-induced diabetic rats.
Topics: Animals; Antioxidants; Blood Glucose; Diabetes Mellitus, Experimental; Gene Expression; Glycogen; Glycolysis; Hypoglycemic Agents; Intracellular Signaling Peptides and Proteins; Lipid Peroxidation; Liver; Male; Malondialdehyde; Phosphoenolpyruvate Carboxykinase (GTP); Picolinic Acids; Rats, Wistar; Streptozocin; Vanadium Compounds | 2014 |
Protective effects of geraniol (a monoterpene) in a diabetic neuropathy rat model: attenuation of behavioral impairments and biochemical perturbations.
Topics: Acyclic Monoterpenes; Administration, Oral; Animals; Body Weight; Brain; Diabetes Mellitus, Experimental; Diabetic Neuropathies; Disease Models, Animal; Hydrogen Peroxide; Hyperalgesia; Hypoglycemic Agents; Lipid Peroxidation; Male; Malondialdehyde; Oxidoreductases; Psychomotor Disorders; Rats; Rats, Wistar; Reactive Oxygen Species; Sciatic Nerve; Terpenes | 2014 |
AGE-breaker ALT-711 plus insulin could restore erectile function in streptozocin-induced type 1 diabetic rats.
Topics: Animals; Apoptosis; Blood Glucose; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Erectile Dysfunction; Hypoglycemic Agents; Insulin; Male; Malondialdehyde; Nitric Oxide Synthase Type I; Oxidative Stress; Penile Erection; Penis; Random Allocation; Rats; Rats, Sprague-Dawley; Receptor for Advanced Glycation End Products; Receptors, Immunologic; Thiazoles | 2014 |
Effects of N-adamantyl-4-methylthiazol-2-amine on hyperglycemia, hyperlipidemia and oxidative stress in streptozotocin-induced diabetic rats.
Topics: Adamantane; Animals; Anti-Inflammatory Agents; Antioxidants; Ascorbic Acid; Blood Glucose; Catalase; Diabetes Mellitus, Experimental; Glutathione; Hyperglycemia; Hyperlipidemias; Hypoglycemic Agents; Hypolipidemic Agents; Insulin; Interleukin-1beta; Lipid Metabolism; Lipid Peroxidation; Liver; Male; Malondialdehyde; NF-kappa B; Nitric Oxide; Oxidative Stress; Rats, Sprague-Dawley; Superoxide Dismutase; Thiazoles; Tumor Necrosis Factor-alpha; Vitamin E | 2014 |
Amelioration of streptozotocin-induced diabetic nephropathy by melatonin, quercetin, and resveratrol in rats.
Topics: Animals; Antioxidants; Blood Glucose; Blood Urea Nitrogen; Catalase; Creatinine; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Glutathione; Kidney; Male; Malondialdehyde; Melatonin; Quercetin; Rats, Wistar; Resveratrol; Stilbenes; Superoxide Dismutase | 2015 |
Pyrrolidine dithiocarbamate protects pancreatic β-cells from oxidative damage through regulation of FoxO1 activity in type 2 diabetes rats.
Topics: Animals; Antioxidants; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Forkhead Transcription Factors; Glutathione Peroxidase; Insulin; Islets of Langerhans; Male; Malondialdehyde; Nerve Tissue Proteins; Oxidative Stress; Pyrrolidines; Rats; Rats, Wistar; Superoxide Dismutase; Thiocarbamates | 2014 |
Electroacupuncture pretreatment inhibits NADPH oxidase-mediated oxidative stress in diabetic mice with cerebral ischemia.
Topics: Acetophenones; Animals; Brain; Brain Ischemia; Cinnamates; Diabetes Mellitus, Experimental; Electroacupuncture; Enzyme Activators; Male; Malondialdehyde; Mice, Inbred C57BL; NADPH Oxidases; Oxidative Stress; Random Allocation; Reactive Oxygen Species; Reperfusion Injury | 2014 |
Endothelin receptor inhibition with bosentan delays onset of liver injury in streptozotocin-induced diabetic condition.
Topics: Animals; Bosentan; Chemical and Drug Induced Liver Injury; Diabetes Mellitus, Experimental; Endothelin Receptor Antagonists; Endothelin-1; Gene Expression Regulation; Glutathione; Liver; Male; Malondialdehyde; Rats; Streptozocin; Sulfonamides; Superoxide Dismutase; Transforming Growth Factor beta; Tumor Necrosis Factor-alpha | 2015 |
Protective effects of vitamins (C and E) and melatonin co-administration on hematological and hepatic functions and oxidative stress in alloxan-induced diabetic rats.
Topics: Alanine Transaminase; Animals; Antioxidants; Ascorbic Acid; Aspartate Aminotransferases; Blood Glucose; Diabetes Mellitus, Experimental; Drug Synergism; Drug Therapy, Combination; Lipids; Liver; Male; Malondialdehyde; Melatonin; Oxidative Stress; Rats; Rats, Wistar; Vitamin E | 2014 |
Melatonin prevents retinal oxidative stress and vascular changes in diabetic rats.
Topics: Animals; Antioxidants; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Diabetic Retinopathy; Enzyme-Linked Immunosorbent Assay; Eye Proteins; Hyperglycemia; Hypoxia-Inducible Factor 1, alpha Subunit; Injections, Intraperitoneal; Male; Malondialdehyde; Melatonin; Nerve Growth Factors; Oxidative Stress; Platelet Endothelial Cell Adhesion Molecule-1; Rats; Rats, Wistar; Retinal Vessels; Serpins; Tyrosine; Vascular Endothelial Growth Factor A | 2014 |
Protective effects of saffron (its active constituent, crocin) on nephropathy in streptozotocin-induced diabetic rats.
Topics: Animals; Blood Urea Nitrogen; Carotenoids; Creatinine; Crocus; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Female; Glutathione; Kidney; Malondialdehyde; Oxidative Stress; Protective Agents; Rats, Wistar; Xanthine Oxidase | 2015 |
The protective effects of Ziziphus vulgaris L. fruits on biochemical and histological abnormalities induced by diabetes in rats.
Topics: Animals; Antioxidants; Blood Glucose; C-Reactive Protein; Diabetes Mellitus, Experimental; Fruit; Hypoglycemic Agents; Inflammation; Insulin; Kaempferols; Lipids; Male; Malondialdehyde; Pancreas; Phytotherapy; Plant Extracts; Powders; Rats, Wistar; Ziziphus | 2014 |
[Effect of sequoyitol on expression of NOX4 and eNOS in aortas of type 2 diabetic rats].
Topics: Animals; Aorta; Blood Glucose; Body Weight; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Hypoglycemic Agents; Inositol; Insulin; Insulin Resistance; Male; Malondialdehyde; NADPH Oxidase 4; NADPH Oxidases; Nitric Oxide; Nitric Oxide Synthase Type III; Oxidation-Reduction; Rats; Rats, Sprague-Dawley; Streptozocin; Vasodilation | 2014 |
Obtusifolin treatment improves hyperlipidemia and hyperglycemia: possible mechanism involving oxidative stress.
Topics: Animals; Anthraquinones; Antioxidants; Blood Glucose; Body Weight; Catalase; Cholesterol; Diabetes Mellitus, Experimental; Glutathione; Glutathione Peroxidase; Hyperlipidemias; Lipid Peroxidation; Malondialdehyde; Nitric Oxide; Oxidative Stress; Rats; Rats, Wistar; Streptozocin; Superoxide Dismutase; Triglycerides | 2014 |
Effect of renin inhibition on adipokines in diabetic rats.
Topics: Adiponectin; Animals; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Lipids; Male; Malondialdehyde; Rats; Rats, Sprague-Dawley; Renin; Streptozocin; Superoxide Dismutase; Tumor Necrosis Factor-alpha | 2014 |
Ethanol at low concentration attenuates diabetes induced lung injury in rats model.
Topics: Aldehyde Dehydrogenase; Aldehyde Dehydrogenase, Mitochondrial; Animals; Blood Glucose; Body Weight; Central Nervous System Depressants; Diabetes Complications; Diabetes Mellitus, Experimental; Dose-Response Relationship, Drug; Ethanol; Gene Expression Regulation; Lung; Lung Injury; Male; Malondialdehyde; Mitochondrial Proteins; Rats; Rats, Sprague-Dawley; Streptozocin; Superoxide Dismutase | 2014 |
The protective effect of granulocyte colony-stimulating factor on endometrium and ovary in a rat model of diabetes mellitus.
Topics: Animals; Diabetes Mellitus, Experimental; Endometrium; Female; Granulocyte Colony-Stimulating Factor; Malondialdehyde; Ovarian Diseases; Ovary; Primary Ovarian Insufficiency; Rats; Rats, Sprague-Dawley; Transforming Growth Factor beta; Uterine Diseases | 2014 |
Hypoglycemic effect of Gynostemma pentaphyllum saponins by enhancing the Nrf2 signaling pathway in STZ-inducing diabetic rats.
Topics: Animals; Antioxidants; Biomarkers; Blood Glucose; Diabetes Mellitus, Experimental; Glutathione Peroxidase; Gynostemma; Hypoglycemic Agents; Insulin; Kidney; Lipids; Liver; Male; Malondialdehyde; NF-E2-Related Factor 2; Oxidative Stress; Phytotherapy; Plant Extracts; Plants, Medicinal; Rats, Wistar; Saponins; Signal Transduction; Superoxide Dismutase | 2016 |
Protocatechuic acid exerts a cardioprotective effect in type 1 diabetic rats.
Topics: Administration, Oral; Animals; Anticarcinogenic Agents; Blotting, Western; Cardiotonic Agents; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Drug Therapy, Combination; Echocardiography; Glycated Hemoglobin; Heart; Hydroxybenzoates; Hypoglycemic Agents; Insulin; Male; Malondialdehyde; Mitochondria, Heart; Myocardium; Proto-Oncogene Proteins c-bcl-2; Rats; Rats, Sprague-Dawley | 2014 |
Glucose fluctuations increase the incidence of atrial fibrillation in diabetic rats.
Topics: Actins; Action Potentials; Animals; Apoptosis; Atrial Fibrillation; Biomarkers; Blood Glucose; Carrier Proteins; Caspase 3; Cell Cycle Proteins; Cells, Cultured; Collagen Type I; Collagen Type III; Diabetes Mellitus, Experimental; Diabetic Cardiomyopathies; Fibrosis; Hypoglycemic Agents; Insulin, Long-Acting; Male; Malondialdehyde; Myocardium; Oxidative Stress; Rats, Sprague-Dawley; Reactive Oxygen Species; Refractory Period, Electrophysiological; Signal Transduction; Time Factors; Ventricular Dysfunction, Left; Ventricular Function, Left | 2014 |
Antidiabetic effect of Lactobacillus casei CCFM0412 on mice with type 2 diabetes induced by a high-fat diet and streptozotocin.
Topics: Animals; Antioxidants; Blood Glucose; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Diet, High-Fat; Dyslipidemias; Endotoxins; Glucose Intolerance; Glycated Hemoglobin; Hypoglycemic Agents; Insulin; Islets of Langerhans; Lacticaseibacillus casei; Lipids; Male; Malondialdehyde; Mice, Inbred C57BL; Oxidative Stress; Streptozocin; Tumor Necrosis Factor-alpha | 2014 |
Protective Effect of Lavandula stoechas and Rosmarinus officinalis essential oils against reproductive damage and oxidative stress in alloxan-induced diabetic rats.
Topics: Alloxan; Animals; Antioxidants; Body Weight; Catalase; Diabetes Mellitus, Experimental; Epididymis; Glutathione Peroxidase; Hydrogen Peroxide; Lavandula; Male; Malondialdehyde; Oils, Volatile; Oxidative Stress; Phytotherapy; Plant Oils; Rats; Rats, Wistar; Rosmarinus; Semen Analysis; Spermatozoa; Sulfhydryl Compounds; Superoxide Dismutase; Testis; Testosterone | 2015 |
Protective effect of chemically modified SOD on lipid peroxidation and antioxidant status in diabetic rats.
Topics: Animals; Antioxidants; Brain; Carboxymethylcellulose Sodium; Cattle; Chromatography, Gel; Diabetes Mellitus, Experimental; Enzyme Stability; Kidney; Lipid Peroxidation; Liver; Maleates; Malondialdehyde; Polyethylenes; Protective Agents; Rats; Rats, Sprague-Dawley; Superoxide Dismutase | 2015 |
Spironolactone improves endothelial dysfunction in streptozotocin-induced diabetic rats.
Topics: Administration, Oral; Animals; Antioxidants; Aorta; Diabetes Mellitus, Experimental; Diabetic Angiopathies; Endothelium, Vascular; Male; Malondialdehyde; Mineralocorticoid Receptor Antagonists; Nitric Oxide; Nitric Oxide Synthase Type III; Rats; Rats, Wistar; Spironolactone; Streptozocin | 2014 |
Combination therapy with losartan and L-carnitine protects against endothelial dysfunction of streptozotocin-induced diabetic rats.
Topics: Acetylcholine; Animals; Aorta; Carnitine; Diabetes Mellitus, Experimental; Drug Therapy, Combination; Endothelium, Vascular; Losartan; Male; Malondialdehyde; Nitric Oxide; Nitric Oxide Synthase Type III; Oxidative Stress; Protective Agents; Rats; Rats, Wistar; Receptors, Angiotensin; Streptozocin; Superoxides; Tumor Necrosis Factor-alpha; Vasodilation; Vasodilator Agents | 2014 |
Rapamycin inhibits oxidative and angiogenic mediators in diabetic retinopathy.
Topics: Angiogenesis Modulating Agents; Animals; Anti-Bacterial Agents; Diabetes Mellitus, Experimental; Diabetic Retinopathy; Eye Proteins; Hypoxia-Inducible Factor 1, alpha Subunit; Male; Malondialdehyde; Nerve Growth Factors; Oxidative Stress; Rats; Rats, Wistar; Serpins; Sirolimus; Tyrosine; Vascular Endothelial Growth Factor A | 2014 |
Hypoglycemic effects of glycosaminoglycan from Urechis unicinctus in diabetic mice.
Topics: Animals; Annelida; Blood Glucose; Diabetes Mellitus, Experimental; Glucokinase; Glutathione Peroxidase; Glycosaminoglycans; Hypoglycemic Agents; Insulin; Liver Glycogen; Malondialdehyde; Mice; Streptozocin; Superoxide Dismutase | 2015 |
Moringa oleifera leaf extract ameliorates alloxan-induced diabetes in rats by regeneration of β cells and reduction of pyruvate carboxylase expression.
Topics: Alloxan; Animals; Blood Glucose; Cholesterol; Diabetes Mellitus, Experimental; Female; Gene Expression Regulation; Gluconeogenesis; Glucose; Hepatocytes; Hypoglycemic Agents; Insulin-Secreting Cells; Liver; Malondialdehyde; Moringa oleifera; Pancreas; Phytotherapy; Plant Extracts; Plant Leaves; Pyruvate Carboxylase; Rats; Rats, Wistar; Triglycerides | 2014 |
Protective effects of grape seed extract fractions with different degrees of polymerisation on blood glucose, lipids and hepatic oxidative stress in diabetic rats.
Topics: Animals; Blood Glucose; Body Weight; Diabetes Mellitus, Experimental; Grape Seed Extract; Lipids; Liver; Malondialdehyde; Metformin; Nitric Oxide; Oxidative Stress; Polymerization; Rats; Rats, Sprague-Dawley | 2015 |
Effects of grape seed proanthocyanidin extract on renal injury in type 2 diabetic rats.
Topics: Animals; Antioxidants; Blood Glucose; Blood Pressure; Body Weight; C-Reactive Protein; Catalase; Chemokine CCL2; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Diet, High-Fat; Glycated Hemoglobin; Grape Seed Extract; Insulin; Intercellular Adhesion Molecule-1; Kidney Diseases; Male; Malondialdehyde; Matrix Metalloproteinase 9; Proanthocyanidins; Rats; Streptozocin; Superoxide Dismutase; Tissue Inhibitor of Metalloproteinase-1; Tumor Necrosis Factor-alpha | 2015 |
Anti-depressant effect of hesperidin in diabetic rats.
Topics: Animals; Antidepressive Agents; Behavior, Animal; Biogenic Monoamines; Brain-Derived Neurotrophic Factor; Depression; Diabetes Mellitus, Experimental; Fluoxetine; Glutathione; Hesperidin; Hyperglycemia; Inflammation; Interleukin-6; Male; Malondialdehyde; Oxidative Stress; Rats, Wistar; Streptozocin | 2014 |
Exenatide improves ovarian and endometrial injury and preserves ovarian reserve in streptozocin induced diabetic rats.
Topics: Animals; Anti-Mullerian Hormone; C-Reactive Protein; Diabetes Mellitus, Experimental; Endometrium; Exenatide; Female; Inflammation; Lipid Peroxidation; Malondialdehyde; Ovarian Reserve; Ovary; Oxidative Stress; Peptides; Rats; Rats, Sprague-Dawley; Serum Amyloid P-Component; Transforming Growth Factor beta; Venoms | 2015 |
The anti-oxidant effects of ginger and cinnamon on spermatogenesis dys-function of diabetes rats.
Topics: Animals; Antioxidants; Catalase; Cinnamomum zeylanicum; Diabetes Complications; Diabetes Mellitus, Experimental; Drug Combinations; Epididymis; Lipid Peroxidation; Male; Male Urogenital Diseases; Malondialdehyde; Oxidative Stress; Phytotherapy; Plant Extracts; Rats, Wistar; Sperm Count; Sperm Motility; Spermatogenesis; Spermatozoa; Testis; Testosterone; Zingiber officinale | 2014 |
Vitamin B6 supplementation improves oxidative stress and enhances serum paraoxonase/arylesterase activities in streptozotocin-induced diabetic rats.
Topics: Administration, Oral; Animals; Antioxidants; Aryldialkylphosphatase; Atherosclerosis; Carboxylic Ester Hydrolases; Cholesterol; Diabetes Mellitus, Experimental; Drug Administration Schedule; Enzyme Activation; Erythrocytes; Glutathione Peroxidase; Male; Malondialdehyde; Oxidative Stress; Rats; Rats, Wistar; Streptozocin; Superoxide Dismutase; Vitamin B 6 | 2014 |
Ginsenoside Rg3 improves erectile function in streptozotocin-induced diabetic rats.
Topics: Actins; Animals; Caspase 3; Diabetes Mellitus, Experimental; Dose-Response Relationship, Drug; Erectile Dysfunction; Ginsenosides; Male; Malondialdehyde; Nitric Oxide Synthase; Penile Erection; Penis; Platelet Endothelial Cell Adhesion Molecule-1; Random Allocation; Rats; Rats, Sprague-Dawley; Streptozocin; Superoxide Dismutase | 2015 |
Modulating actions of NMDA receptors on pronociceptive effects of locally injected remifentanil in diabetic rats.
Topics: Analgesics, Opioid; Animals; Diabetes Mellitus, Experimental; Diabetic Neuropathies; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Hyperalgesia; Malondialdehyde; N-Methylaspartate; Nitric Oxide; Piperidines; Rats; Receptors, N-Methyl-D-Aspartate; Receptors, Opioid, mu; Remifentanil; Streptozocin | 2014 |
Combination therapy with spironolactone and candesartan protects against streptozotocin-induced diabetic nephropathy in rats.
Topics: Animals; Antioxidants; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Cyclooxygenase 2; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Drug Therapy, Combination; Inflammation; Kidney; Male; Malondialdehyde; NF-kappa B; Nitric Oxide; Nitric Oxide Synthase Type II; Oxidative Stress; Protective Agents; Rats; Rats, Wistar; Spironolactone; Streptozocin; Superoxides; Tetrazoles; Transforming Growth Factor beta | 2014 |
Piperine, a natural bioenhancer, nullifies the antidiabetic and antioxidant activities of curcumin in streptozotocin-diabetic rats.
Topics: Alanine Transaminase; Alkaloids; Animals; Antioxidants; Benzodioxoles; Blood Glucose; Body Weight; Catalase; Curcumin; Diabetes Mellitus, Experimental; Drug Interactions; Glutathione Peroxidase; Hypoglycemic Agents; Lipid Peroxidation; Liver; Male; Malondialdehyde; Oxidative Stress; Piperidines; Polyunsaturated Alkamides; Rats, Wistar; Superoxide Dismutase; Treatment Outcome | 2014 |
Hypoxia-induced acute lung injury is aggravated in streptozotocin diabetic mice.
Topics: Acute Lung Injury; Animals; Antioxidants; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Hypoxia; Interleukin-1beta; Interleukin-6; Lung; Male; Malondialdehyde; Mice; Mice, Inbred ICR; Neutrophil Infiltration; Peroxidase; Pneumonia; Streptozocin; Superoxide Dismutase; Toll-Like Receptor 4 | 2015 |
Comparison on hypoglycemic and antioxidant activities of the fresh and dried Portulaca oleracea L. in insulin-resistant HepG2 cells and streptozotocin-induced C57BL/6J diabetic mice.
Topics: Animals; Antioxidants; Blood Glucose; Cell Survival; Diabetes Mellitus, Experimental; Hep G2 Cells; Humans; Hypoglycemic Agents; Insulin; Insulin Resistance; Liver; Male; Malondialdehyde; Mice, Inbred C57BL; Phytotherapy; Plant Extracts; Portulaca; Superoxide Dismutase | 2015 |
Diabetes and alcohol: Double jeopardy with regard to oxidative toxicity and sexual dysfunction in adult male Wistar rats.
Topics: 17-Hydroxysteroid Dehydrogenases; Animals; Catalase; Diabetes Mellitus, Experimental; Epididymis; Ethanol; Follicle Stimulating Hormone; Luteinizing Hormone; Male; Malondialdehyde; Organ Size; Oxidative Stress; Rats, Wistar; Spermatozoa; Superoxide Dismutase; Testis; Testosterone | 2015 |
Protective effect of rhGLP-1 (7-36) on brain ischemia/reperfusion damage in diabetic rats.
Topics: Animals; Blood Glucose; Brain; Brain Ischemia; Diabetes Mellitus, Experimental; Dose-Response Relationship, Drug; Glucagon-Like Peptide 1; Glutathione Peroxidase; Hypoglycemic Agents; Infarction, Middle Cerebral Artery; Male; Malondialdehyde; Neuroprotective Agents; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Peptide Fragments; Random Allocation; Rats, Sprague-Dawley; Reperfusion Injury; Severity of Illness Index; Superoxide Dismutase | 2015 |
Evaluation of hypoglycemic effects of polyphenols and extracts from Penthorum chinense.
Topics: Animals; Blood Glucose; Diabetes Mellitus, Experimental; Diet, High-Fat; Female; Glutathione; Glycated Hemoglobin; Hypoglycemic Agents; Insulin; Malondialdehyde; Mice, Inbred ICR; Phytotherapy; Plant Components, Aerial; Plant Extracts; Polyphenols; Rats, Wistar; Superoxide Dismutase; Tracheophyta | 2015 |
Loganin attenuates diabetic nephropathy in C57BL/6J mice with diabetes induced by streptozotocin and fed with diets containing high level of advanced glycation end products.
Topics: Analysis of Variance; Animals; Blood Urea Nitrogen; Blotting, Western; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Disease Models, Animal; DNA Primers; Dose-Response Relationship, Drug; Gene Expression Regulation; Glycation End Products, Advanced; Iridoids; Kidney; Malondialdehyde; Mice; Mice, Inbred C57BL; Microscopy, Electron, Transmission; Molecular Structure; Oxidative Stress; Pancreas; Proteinuria; Receptor for Advanced Glycation End Products; Receptors, Immunologic; Reverse Transcriptase Polymerase Chain Reaction; Superoxide Dismutase | 2015 |
Physico-chemical properties and hypoglycaemic activity of fermented milks prepared with Anemarrhena asphodeloides water extracts.
Topics: Anemarrhena; Animals; Bifidobacterium; Blood Glucose; Cultured Milk Products; Diabetes Mellitus, Experimental; Insulin; Lactobacillus; Malondialdehyde; Mice; Plant Exudates; Streptococcus thermophilus; Superoxide Dismutase; Water | 2016 |
Anti-diabetic potential of chromium histidinate in diabetic retinopathy rats.
Topics: Animals; Blood Glucose; Cholesterol; Chromium; Diabetes Mellitus, Experimental; Diabetic Retinopathy; Dietary Supplements; Glucose Transporter Type 1; Glucose Transporter Type 3; Glycated Hemoglobin; Histidine; Hypoglycemic Agents; Insulin; Male; Malondialdehyde; Organometallic Compounds; Oxidative Stress; Rats; Rats, Long-Evans; Rats, Wistar; Retina | 2015 |
Beneficial Effects of Endurance Exercise with Rosmarinus officinalis Labiatae Leaves Extract on Blood Antioxidant Enzyme Activities and Lipid Peroxidation in Streptozotocin-Induced Diabetic Rats.
Topics: Animals; Blood Glucose; Catalase; Diabetes Mellitus, Experimental; Disease Models, Animal; Glutathione Peroxidase; Insulin; Lipid Peroxidation; Male; Malondialdehyde; Oxidative Stress; Physical Conditioning, Animal; Physical Endurance; Plant Extracts; Plant Leaves; Rats; Rats, Wistar; Rosmarinus; Streptozocin; Superoxide Dismutase | 2015 |
Antihyperglycemic activity of Anoectochilus roxburghii polysaccharose in diabetic mice induced by high-fat diet and streptozotocin.
Topics: Alanine Transaminase; Animals; Aspartate Aminotransferases; Blood Glucose; Body Weight; Cholesterol; Diabetes Mellitus, Experimental; Diet, High-Fat; Eating; Glycogen; Hypoglycemic Agents; Liver; Male; Malondialdehyde; Mice, Inbred ICR; Orchidaceae; Pancreas; Plant Extracts; Streptozocin; Superoxide Dismutase; Toxicity Tests, Acute; Triglycerides | 2015 |
Protective effects of resveratrol against streptozotocin-induced diabetes in rats by modulation of visfatin/sirtuin-1 pathway and glucose transporters.
Topics: Animals; Antioxidants; Blood Glucose; Diabetes Mellitus, Experimental; Dietary Supplements; Glucose Transport Proteins, Facilitative; Hyperglycemia; Hypoglycemic Agents; Male; Malondialdehyde; Muscle, Skeletal; Nicotinamide Phosphoribosyltransferase; Oxidative Stress; Pancreas; Phytotherapy; Plant Extracts; Polyphenols; Rats, Wistar; Resveratrol; Sirtuin 1; Stilbenes; Weight Loss | 2015 |
Flaxseed oil reduces oxidative stress and enhances brain monoamines release in streptozotocin-induced diabetic rats.
Topics: Animals; Blood Glucose; Brain; Diabetes Mellitus, Experimental; Dietary Supplements; Dopamine; Insulin; Linseed Oil; Male; Malondialdehyde; Nitric Oxide; Norepinephrine; Oxidative Stress; Rats, Sprague-Dawley; Serotonin | 2015 |
Losartan reduces oxidative damage to renal DNA and conserves plasma antioxidant capacity in diabetic rats.
Topics: 8-Hydroxy-2'-Deoxyguanosine; Adiponectin; Angiotensin II Type 1 Receptor Blockers; Animals; Antioxidants; Deoxyguanosine; Diabetes Mellitus, Experimental; DNA; DNA Damage; Enzyme-Linked Immunosorbent Assay; Hyperglycemia; Kidney; Lipids; Losartan; Malondialdehyde; Oxidative Stress; Oxygen; Random Allocation; Rats; Rats, Wistar; Reactive Oxygen Species | 2015 |
Ginkgolide B increases hydrogen sulfide and protects against endothelial dysfunction in diabetic rats.
Topics: Acetylcholine; Animals; Cystathionine gamma-Lyase; Diabetes Mellitus, Experimental; Endothelium, Vascular; Fibrinolytic Agents; Ginkgolides; Glutathione Peroxidase; Glutathione Peroxidase GPX1; Hydrogen Sulfide; Lactones; Male; Malondialdehyde; NADPH Oxidases; Nitric Oxide; Nitric Oxide Synthase Type III; Nitroprusside; Oxidative Stress; Rats; Rats, Sprague-Dawley; Superoxide Dismutase | 2015 |
Nephrotoxic effects of lead nitrate exposure in diabetic and nondiabetic rats: Involvement of oxidative stress and the protective role of sodium selenite.
Topics: Animals; Antioxidants; Blood Urea Nitrogen; Body Weight; Creatinine; Diabetes Mellitus, Experimental; Kidney; Lead; Male; Malondialdehyde; Nitrates; Oxidative Stress; Protective Agents; Rats; Rats, Wistar; Sodium Selenite; Uric Acid | 2016 |
Protective effect of some selected fruit blends on testicular toxicity in alloxan-induced diabetic rats.
Topics: Animals; Antioxidants; Carica; Catalase; Citrus; Diabetes Mellitus, Experimental; Fruit; Glutathione; Glutathione Peroxidase; Lipid Peroxidation; Male; Malondialdehyde; Oxidative Stress; Plant Preparations; Psidium; Rats, Wistar; Sperm Count; Sperm Motility; Spermatozoa; Superoxide Dismutase; Testicular Diseases; Testis | 2015 |
Evaluation of the actions of metformin and taurine, singly and in combination, on metabolic and oxidative alterations caused by diabetes in rat erythrocytes and plasma.
Topics: Animals; Blood Glucose; Diabetes Mellitus, Experimental; Erythrocytes; Glycated Hemoglobin; Insulin; Male; Malondialdehyde; Metformin; Oxidative Stress; Rats; Rats, Sprague-Dawley; Taurine | 2015 |
Combination of vitamin E and folic acid ameliorate oxidative stress and apoptosis in diabetic rat uterus.
Topics: Animals; Apoptosis; Caspase 3; Catalase; Diabetes Complications; Diabetes Mellitus, Experimental; Drug Therapy, Combination; Female; Folic Acid; Glutathione; Glutathione Peroxidase; Glutathione Reductase; Malondialdehyde; Oxidative Stress; Rats; Rats, Sprague-Dawley; Uterus; Vitamin E | 2014 |
Characterization of pumpkin polysaccharides and protective effects on streptozotocin-damaged islet cells.
Topics: Animals; Apoptosis; bcl-2-Associated X Protein; Chromatography, Gas; Chromatography, Gel; Cucurbita; Diabetes Mellitus, Experimental; Islets of Langerhans; Magnetic Resonance Spectroscopy; Malondialdehyde; Molecular Weight; Monosaccharides; Nitric Oxide; Polysaccharides; Rats; Rats, Sprague-Dawley; Reverse Transcriptase Polymerase Chain Reaction; Spectroscopy, Fourier Transform Infrared; Superoxide Dismutase | 2015 |
In vivo systemic chlorogenic acid therapy under diabetic conditions: Wound healing effects and cytotoxicity/genotoxicity profile.
Topics: Animals; Antioxidants; Blood Glucose; Catalase; Chlorogenic Acid; Diabetes Mellitus, Experimental; DNA Damage; Glutathione; Hydroxyproline; Lipid Peroxidation; Male; Malondialdehyde; Nitric Oxide; Oxidative Stress; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Streptozocin; Superoxide Dismutase; Wound Healing | 2015 |
The lung endothelin system: a potent therapeutic target with bosentan for the amelioration of lung alterations in a rat model of diabetes mellitus.
Topics: Acute Lung Injury; Animals; Bosentan; Diabetes Mellitus, Experimental; Endothelin Receptor Antagonists; Glutathione; Lung; Male; Malondialdehyde; Oxidative Stress; Rats; Rats, Wistar; Sulfonamides; Superoxide Dismutase; Transforming Growth Factor beta; Tumor Necrosis Factor-alpha | 2015 |
[Study on hypoglycemic effect and mechanism of total flavonoids of Propolis in STZ diabetic rats].
Topics: Animals; C-Peptide; Diabetes Mellitus, Experimental; Diet, High-Fat; Fatty Acids, Nonesterified; Flavonoids; Glucose; Glycated Hemoglobin; Hypoglycemic Agents; Liver; Malondialdehyde; Propolis; Rats; Streptozocin; Superoxide Dismutase; Tumor Necrosis Factor-alpha | 2014 |
Aminoguanidine mitigates apoptosis, testicular seminiferous tubules damage, and oxidative stress in streptozotocin-induced diabetic rats.
Topics: Animals; Apoptosis; Blood Glucose; Catalase; Diabetes Mellitus, Experimental; Glutathione Peroxidase; Guanidines; Humans; Male; Malondialdehyde; Nitric Oxide; Oxidative Stress; Rats; Seminiferous Tubules; Superoxide Dismutase; Testis | 2015 |
Effects of lead nitrate and sodium selenite on DNA damage and oxidative stress in diabetic and non-diabetic rat erythrocytes and leucocytes.
Topics: Animals; Catalase; Diabetes Mellitus, Experimental; DNA Damage; Erythrocytes; Gene Expression Regulation, Enzymologic; Glutathione Peroxidase; Glutathione Transferase; Lead; Leukocytes; Malondialdehyde; Nitrates; Oxidative Stress; Rats; Sodium Selenite; Superoxide Dismutase | 2015 |
Antidiabetic, antioxidant, and antilipid peroxidative activities of Dracocephalum polychaetum shoot extract in streptozotocin-induced diabetic rats: In vivo and in vitro studies.
Topics: Administration, Oral; Animals; Antioxidants; Biomarkers; Biphenyl Compounds; Blood Glucose; Diabetes Mellitus, Experimental; Dose-Response Relationship, Drug; Glucose Tolerance Test; Hypoglycemic Agents; Hypolipidemic Agents; Lamiaceae; Lipid Peroxidation; Male; Malondialdehyde; Picrates; Plant Extracts; Plant Shoots; Rats, Wistar; Streptozocin | 2016 |
Antidepressant-like and anxiolytic-like effects of hydrogen sulfide in streptozotocin-induced diabetic rats through inhibition of hippocampal oxidative stress.
Topics: Aldehydes; Animals; Anti-Anxiety Agents; Antidepressive Agents; Anxiety Disorders; Blood Glucose; Depressive Disorder; Diabetes Mellitus, Experimental; Glutathione; Hippocampus; Hydrogen Sulfide; Male; Malondialdehyde; Oxidative Stress; Random Allocation; Rats, Sprague-Dawley; Superoxide Dismutase | 2015 |
Ginsenoside Rg1 ameliorates oxidative stress and myocardial apoptosis in streptozotocin-induced diabetic rats.
Topics: Animals; Apoptosis; bcl-X Protein; Blood Glucose; Caspase 3; Central Nervous System Agents; Diabetes Mellitus, Experimental; Ginsenosides; Heart; Immunohistochemistry; In Situ Nick-End Labeling; Male; Malondialdehyde; Microscopy, Electron, Transmission; Myocardium; Oxidative Stress; Rats; Rats, Wistar; Streptozocin | 2015 |
Treadmill training combined with insulin suppresses diabetic nerve pain and cytokines in rat sciatic nerve.
Topics: Animals; Combined Modality Therapy; Cytokines; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Diabetic Neuropathies; Exercise Therapy; Hyperalgesia; Hypoglycemic Agents; Inflammation Mediators; Insulin; Male; Malondialdehyde; Pain Threshold; Rats, Wistar; Reaction Time; Running; Sciatic Nerve; Sciatica; Time Factors | 2015 |
Hypoglycemic, antilipidemic and antioxidant effects of valproic acid in alloxan-induced diabetic rats.
Topics: Animals; Antioxidants; Blood Glucose; Body Weight; Calcium; Cytosol; Diabetes Mellitus, Experimental; Drinking; Hydrogen Peroxide; Hypoglycemic Agents; Hypolipidemic Agents; Insulin-Secreting Cells; Kidney; Lipids; Liver; Male; Malondialdehyde; Organ Size; Rats; Rats, Wistar; Valproic Acid | 2015 |
Metformin attenuates hyperalgesia and allodynia in rats with painful diabetic neuropathy induced by streptozotocin.
Topics: AMP-Activated Protein Kinases; Animals; Diabetes Mellitus, Experimental; Diabetic Neuropathies; Enzyme Activation; Glycation End Products, Advanced; Hyperalgesia; Hypoglycemic Agents; Male; Malondialdehyde; Metformin; Oxidative Stress; Pain Perception; Pain Threshold; Phosphorylation; Rats, Sprague-Dawley; Sciatic Nerve; Streptozocin; Superoxide Dismutase; Time Factors | 2015 |
Effect of Melatonin Intake on Oxidative Stress Biomarkers in Male Reproductive Organs of Rats under Experimental Diabetes.
Topics: Animals; Biomarkers; Catalase; Diabetes Mellitus, Experimental; Glutathione Peroxidase; Glutathione Transferase; Lipid Peroxidation; Male; Malondialdehyde; Melatonin; Oxidative Stress; Rats; Rats, Wistar; Testis | 2015 |
Effects and clinical significance of pentoxifylline on the oxidative stress of rats with diabetic nephropathy.
Topics: Animals; Biomarkers; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Gene Expression Regulation; Kidney; Malondialdehyde; Oxidative Stress; Pentoxifylline; Rats; Streptozocin; Superoxide Dismutase; Tyrosine | 2015 |
Resveratrol regulates oxidative biomarkers and antioxidant enzymes in the brain of streptozotocin-induced diabetic rats.
Topics: Animals; Antioxidants; Biomarkers; Diabetes Mellitus, Experimental; Diabetic Neuropathies; Frontal Lobe; Gene Expression Regulation, Enzymologic; Glutathione; Male; Malondialdehyde; Neuroprotective Agents; Oxidative Stress; Rats, Wistar; Resveratrol; Stilbenes; Streptozocin | 2016 |
Inflammatory Macrophages Promotes Development of Diabetic Encephalopathy.
Topics: Animals; Antibodies; Blood Glucose; Brain Chemistry; Brain Diseases; Catalase; CD11b Antigen; Cell Count; Diabetes Mellitus, Experimental; Gene Expression; Immunotoxins; Insulin; Insulin-Secreting Cells; Macrophages; Male; Malondialdehyde; Mice; Mice, Inbred C57BL; Nitric Oxide; Rats; Ribosome Inactivating Proteins, Type 1; Saporins; Streptozocin; Superoxide Dismutase | 2015 |
Erythropoietin improves glucose metabolism and pancreatic β-cell damage in experimental diabetic rats.
Topics: Animals; Blood Glucose; Carbohydrate Metabolism; Diabetes Mellitus, Experimental; Disease Models, Animal; Erythropoietin; Fasting; Glucose; Glucose Tolerance Test; Glutathione Peroxidase; Hematopoiesis; Insulin; Insulin-Secreting Cells; Male; Malondialdehyde; Rats; Selenium; Superoxide Dismutase | 2015 |
Alterations in Hippocampal Oxidative Stress, Expression of AMPA Receptor GluR2 Subunit and Associated Spatial Memory Loss by Bacopa monnieri Extract (CDRI-08) in Streptozotocin-Induced Diabetes Mellitus Type 2 Mice.
Topics: Animals; Bacopa; CA3 Region, Hippocampal; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Drug Evaluation, Preclinical; Gene Expression; Hypoglycemic Agents; Male; Malondialdehyde; Maze Learning; Memory Disorders; Mice; Oxidative Stress; Plant Extracts; Receptors, AMPA; Spatial Memory; Streptozocin | 2015 |
Effects of kolaviron on hepatic oxidative stress in streptozotocin induced diabetes.
Topics: Animals; Antioxidants; Apoptosis; Catalase; Diabetes Mellitus, Experimental; Flavonoids; Garcinia kola; Glutathione; Glutathione Peroxidase; Hyperglycemia; Lipid Peroxidation; Liver; Male; Malondialdehyde; Oxidative Stress; Phytotherapy; Plant Extracts; Rats; Rats, Wistar; Seeds; Superoxide Dismutase | 2015 |
Levosimendan suppresses oxidative injury, apoptotic signaling and mitochondrial degeneration in streptozotocin-induced diabetic cardiomyopathy.
Topics: Animals; Apoptosis; C-Reactive Protein; Cardiotonic Agents; Caspase 3; Diabetes Mellitus, Experimental; Diabetic Cardiomyopathies; Glutathione Peroxidase; Hydrazones; Hypoglycemic Agents; Insulin; Male; Malondialdehyde; Oxidative Stress; Pyridazines; Ramipril; Rats; Rats, Wistar; Simendan; Superoxide Dismutase; Tumor Necrosis Factor-alpha | 2016 |
Anti-diabetic activity of peony seed oil, a new resource food in STZ-induced diabetic mice.
Topics: alpha-Amylases; alpha-Glucosidases; Animals; Blood Glucose; Diabetes Mellitus, Experimental; Female; Glycated Hemoglobin; Humans; Hypoglycemic Agents; Insulin; Lipoproteins, HDL; Male; Malondialdehyde; Mice; Mice, Inbred ICR; Paeonia; Plant Oils; Seeds; Streptozocin; Superoxide Dismutase | 2015 |
Amelioration of chronic inflammation and oxidative stress indices in diabetic Wistar rats using methanol leaf extract of Bridelia micrantha (Hochst) Baill. (Euphorbiaceae).
Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Blood Glucose; Catalase; Chronic Disease; Diabetes Mellitus, Experimental; Euphorbiaceae; Female; Glutathione; Granuloma; Inflammation; Male; Malondialdehyde; Oxidative Stress; Phytotherapy; Plant Extracts; Plant Leaves; Rats, Wistar; Superoxide Dismutase | 2015 |
Melatonin and selenium reduce plasma cytokine and brain oxidative stress levels in diabetic rats.
Topics: Animals; Antioxidants; Brain; Cytokines; Diabetes Mellitus, Experimental; Female; Glutathione Peroxidase; Hyperglycemia; Lipid Peroxidation; Malondialdehyde; Melatonin; Oxidative Stress; Rats; Rats, Wistar; Selenium; Vitamin E | 2015 |
Levetiracetam ameliorates ovarian function in streptozotocin-induced diabetic rats.
Topics: Animals; Anti-Mullerian Hormone; Blood Glucose; Diabetes Mellitus, Experimental; Female; Glutathione; Levetiracetam; Lipid Peroxidation; Malondialdehyde; Ovary; Oxidative Stress; Piracetam; Rats; Rats, Sprague-Dawley; Streptozocin | 2015 |
Amelioration of experimentally induced diabetic nephropathy and renal damage by nilotinib.
Topics: Animals; Blood Urea Nitrogen; Collagen; Creatinine; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Drug Evaluation, Preclinical; Glutathione; Hydroxyproline; Kidney; Male; Malondialdehyde; Oxidative Stress; Protein Kinase Inhibitors; Pyrimidines; Rats, Sprague-Dawley; Superoxide Dismutase; Toll-Like Receptor 4; Transcription Factor RelA | 2015 |
Polysaccharides from Enteromorpha prolifera Improve Glucose Metabolism in Diabetic Rats.
Topics: Adiponectin; Adipose Tissue; Animals; Blood Glucose; Chlorophyta; Diabetes Mellitus, Experimental; Dose-Response Relationship, Drug; Glucokinase; Glucose Tolerance Test; Glucose Transporter Type 4; Glutathione Peroxidase; Hypoglycemic Agents; Insulin; Insulin Resistance; Liver; Male; Malondialdehyde; Pancreas; Polysaccharides; Rats; Rats, Sprague-Dawley; Receptor, Insulin; RNA, Messenger; Superoxide Dismutase | 2015 |
The Effects of Probiotic Soymilk Fortified with Omega-3 on Blood Glucose, Lipid Profile, Haematological and Oxidative Stress, and Inflammatory Parameters in Streptozotocin Nicotinamide-Induced Diabetic Rats.
Topics: Animals; Blood Glucose; Body Weight; C-Reactive Protein; Cholesterol; Diabetes Mellitus, Experimental; Erythrocytes; Fatty Acids, Omega-3; Fermentation; Hematocrit; Hemoglobins; Inflammation; Lipids; Male; Malondialdehyde; Niacinamide; Oxidative Stress; Probiotics; Rats; Rats, Sprague-Dawley; Soy Milk; Streptozocin; Superoxide Dismutase; Triglycerides | 2015 |
Dexmedetomidine protects from post-myocardial ischaemia reperfusion lung damage in diabetic rats.
Topics: Adrenergic alpha-2 Receptor Agonists; Animals; Dexmedetomidine; Diabetes Mellitus, Experimental; Glutathione Transferase; Lung; Lung Injury; Male; Malondialdehyde; Myocardial Ischemia; Myocardial Reperfusion Injury; Random Allocation; Rats; Rats, Wistar | 2015 |
Rosuvastatin ameliorates diabetes-induced reproductive damage via suppression of oxidative stress, inflammatory and apoptotic pathways in male rats.
Topics: Animals; Apoptosis; Biomarkers; Diabetes Mellitus, Experimental; Epididymis; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Infertility, Male; Inflammation; Inflammation Mediators; Male; Malondialdehyde; Nitric Oxide; Oxidative Stress; Rats; Rats, Wistar; Rosuvastatin Calcium; Sperm Count; Sperm Motility; Testis; Testosterone | 2015 |
Protective effect of rosmarinic acid against oxidative stress biomarkers in liver and kidney of strepotozotocin-induced diabetic rats.
Topics: Animals; Antioxidants; Ascorbic Acid; Biomarkers; Blood Glucose; Cinnamates; Depsides; Diabetes Mellitus, Experimental; Drug Evaluation, Preclinical; Kidney; Liver; Male; Malondialdehyde; Oxidative Stress; Rats, Wistar; Rosmarinic Acid; Streptozocin; Superoxide Dismutase; Thiobarbituric Acid Reactive Substances | 2015 |
Effects of Resveratrol on Receptor for Advanced Glycation End Products (RAGE) Expression and Oxidative Stress in the Liver of Rats with Type 2 Diabetes.
Topics: Animals; Antioxidants; Blood Glucose; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Lipid Peroxidation; Liver; Male; Malondialdehyde; Oxidative Stress; Rats; Rats, Wistar; Receptor for Advanced Glycation End Products; Resveratrol; Stilbenes | 2016 |
SIRT1 protects against myocardial ischemia-reperfusion injury via activating eNOS in diabetic rats.
Topics: Acetylation; Animals; Apoptosis; Blotting, Western; Creatine Kinase, MB Form; Diabetes Mellitus, Experimental; Diet, High-Fat; Enzyme Inhibitors; Genetic Vectors; L-Lactate Dehydrogenase; Male; Malondialdehyde; Myocardial Infarction; Myocardial Reperfusion Injury; Myocytes, Cardiac; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase Type III; Oxidative Stress; Phosphorylation; Rats; Rats, Sprague-Dawley; Real-Time Polymerase Chain Reaction; Sirtuin 1; Superoxide Dismutase; Superoxides; Up-Regulation; Ventricular Function, Left | 2015 |
Antidiabetic properties of lyophilized extract of acorn (Quercus brantii Lindl.) on experimentally STZ-induced diabetic rats.
Topics: Alanine Transaminase; Alkaline Phosphatase; Animals; Aspartate Aminotransferases; Blood Glucose; Brain; Diabetes Mellitus, Experimental; Erythrocytes; Freeze Drying; Glutathione Transferase; Glycoside Hydrolases; Hyperglycemia; Hypoglycemic Agents; Intestine, Small; Kidney; Lipid Metabolism; Liver; Male; Malondialdehyde; Nuts; Phytotherapy; Plant Extracts; Quercus; Rats, Wistar | 2015 |
Beneficial effect of D-allose for isolated islet culture prior to islet transplantation.
Topics: Animals; Apoptosis; Caspase 3; Diabetes Mellitus, Experimental; Glucose; Islets of Langerhans; Islets of Langerhans Transplantation; Malondialdehyde; Mice; Mice, Nude; Oxidative Stress; Rats; Stereoisomerism | 2016 |
Protocatechuic Acid Restores Vascular Responses in Rats With Chronic Diabetes Induced by Streptozotocin.
Topics: Animals; Antioxidants; Blood Glucose; Blood Pressure; Catalase; Diabetes Mellitus, Experimental; Heart Rate; Hydroxybenzoates; Insulin; Male; Malondialdehyde; Nitric Oxide; Oxidation-Reduction; Oxidative Stress; Phenylephrine; Rats; Rats, Sprague-Dawley; Streptozocin; Superoxide Dismutase | 2016 |
Luteolin improves the impaired nerve functions in diabetic neuropathy: behavioral and biochemical evidences.
Topics: Animals; Behavior, Animal; Diabetes Mellitus, Experimental; Diabetic Neuropathies; Dose-Response Relationship, Drug; Ganglia, Spinal; Hyperalgesia; Luteolin; Male; Malondialdehyde; Neural Conduction; Neuroprotective Agents; Pain Threshold; Physical Stimulation; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Treatment Outcome | 2015 |
Antidiabetic effect of polysaccharides from Pleurotus ostreatus in streptozotocin-induced diabetic rats.
Topics: Animals; Antioxidants; Blood Glucose; Catalase; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Diet, High-Fat; Glutathione; Glutathione Peroxidase; Glycogen Synthase Kinase 3; Hyperglycemia; Hyperlipidemias; Hypoglycemic Agents; Male; Malondialdehyde; Oxidative Stress; Plant Extracts; Pleurotus; Polysaccharides; Rats; Rats, Wistar; Streptozocin; Superoxide Dismutase | 2016 |
[Protective effects of hydrogen sulfide on diaphragmatic muscle of Type 1 diabetic rats and its anti-apoptotic mechanisms].
Topics: Animals; Apoptosis; Caspase 3; Diabetes Mellitus, Experimental; Diaphragm; Hydrogen Sulfide; Male; Malondialdehyde; Muscle Contraction; Oxidative Stress; Rats; Rats, Sprague-Dawley; Sulfides; Superoxide Dismutase | 2015 |
Astaxanthin reduces type 2 diabetic‑associated cognitive decline in rats via activation of PI3K/Akt and attenuation of oxidative stress.
Topics: Animals; Caspase 3; Caspase 9; Cerebral Cortex; Cognition Disorders; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Gene Expression Regulation; Hippocampus; Humans; Malondialdehyde; Oxidative Stress; Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins c-akt; Rats; Xanthophylls | 2016 |
The antioxidative effects of acidic-, alkalic-, and enzymatic-extractable mycelium zinc polysaccharides by Pleurotus djamor on liver and kidney of streptozocin-induced diabetic mice.
Topics: Animals; Antioxidants; Catalase; Diabetes Mellitus, Experimental; Female; Glutathione; Humans; Kidney; Liver; Male; Malondialdehyde; Mice; Mycelium; Oxidative Stress; Pleurotus; Polysaccharides; Streptozocin; Superoxide Dismutase; Zinc | 2015 |
Elevation of cortical C26:0 due to the decline of peroxisomal β-oxidation potentiates amyloid β generation and spatial memory deficits via oxidative stress in diabetic rats.
Topics: Amyloid beta-Peptides; Amyloid Precursor Protein Secretases; Animals; Aspartic Acid Endopeptidases; Brain; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Fatty Acids; Malondialdehyde; Maze Learning; Membrane Glycoproteins; Memory Disorders; Oxidative Stress; Random Allocation; Rats, Sprague-Dawley; Receptors, Interleukin-1; Spatial Memory | 2016 |
Panax notoginseng saponins protect kidney from diabetes by up-regulating silent information regulator 1 and activating antioxidant proteins in rats.
Topics: Acetylation; Animals; Antioxidants; Blood Glucose; Bone Morphogenetic Protein 7; Chemokine CCL2; Diabetes Mellitus, Experimental; Gene Knockdown Techniques; Immunohistochemistry; Kidney; Kidney Function Tests; Lipids; Male; Malondialdehyde; Mesangial Cells; Oxidative Stress; Panax notoginseng; Plasminogen Activator Inhibitor 1; Protective Agents; Rats, Sprague-Dawley; Saponins; Sirtuin 1; Superoxide Dismutase; Transcription Factor RelA; Transcription, Genetic; Transforming Growth Factor beta1; Up-Regulation | 2016 |
Diabetes in the Cohen Rat Intensifies the Fetal Pancreatic Damage Induced by the Diabetogenic High Sucrose Low Copper Diet.
Topics: 5-Methylcytosine; Animals; Biomarkers; Blood Glucose; Copper; Diabetes Mellitus, Experimental; Diet; Fetus; Immunohistochemistry; Malondialdehyde; Oxidative Stress; Pancreas; Postprandial Period; Rats; Sucrose | 2016 |
Mallotus roxburghianus modulates antioxidant responses in pancreas of diabetic rats.
Topics: Animals; Antioxidants; Blood Glucose; Cytokines; Diabetes Mellitus, Experimental; Drug Evaluation, Preclinical; Hypoglycemic Agents; Lipid Peroxidation; Mallotus Plant; Malondialdehyde; Nicotinamide Phosphoribosyltransferase; Organ Size; Oxidative Stress; Pancreas; Plant Extracts; Proliferating Cell Nuclear Antigen; Rats, Wistar; Superoxide Dismutase | 2016 |
Protective effect of thymoquinone improves cardiovascular function, and attenuates oxidative stress, inflammation and apoptosis by mediating the PI3K/Akt pathway in diabetic rats.
Topics: Animals; Anti-Inflammatory Agents; Apoptosis; Benzoquinones; Blood Glucose; Cardiotonic Agents; Diabetes Mellitus, Experimental; Diabetic Cardiomyopathies; Drug Evaluation, Preclinical; Inflammation; Male; Malondialdehyde; Oxidative Stress; Phosphatidylinositol 3-Kinases; Phosphorylation; Protein Processing, Post-Translational; Proto-Oncogene Proteins c-akt; Rats, Wistar; Signal Transduction; Tumor Necrosis Factor-alpha | 2016 |
Comparative Study of the Antioxidant Effects of Metformin, Glibenclamide, and Repaglinide in Alloxan-Induced Diabetic Rats.
Topics: Alloxan; Animals; Antioxidants; Biomarkers; Blood Glucose; Carbamates; Catalase; Diabetes Complications; Diabetes Mellitus, Experimental; Glutathione; Glyburide; Hypoglycemic Agents; Lipid Peroxidation; Male; Malondialdehyde; Metformin; Oxidative Stress; Piperidines; Rats; Superoxide Dismutase | 2016 |
Nesfatin-1 improves oxidative skin injury in normoglycemic or hyperglycemic rats.
Topics: Animals; Antioxidants; Calcium-Binding Proteins; Caspase 3; Diabetes Mellitus, Experimental; DNA-Binding Proteins; Glutathione; Hyperglycemia; Injections, Intraperitoneal; Interleukin-1beta; Interleukin-6; Male; Malondialdehyde; Neovascularization, Physiologic; Nerve Tissue Proteins; Neutrophil Infiltration; Nucleobindins; Oxidation-Reduction; Peroxidase; Rats; Rats, Sprague-Dawley; Skin; Streptozocin; Surgical Wound; Transforming Growth Factor beta1; Vascular Endothelial Growth Factor A; Wound Healing | 2016 |
Chrysin treatment improves diabetes and its complications in liver, brain, and pancreas in streptozotocin-induced diabetic rats.
Topics: Animals; Antioxidants; Blood Glucose; Brain; Catalase; Diabetes Mellitus, Experimental; Flavonoids; Glutathione Transferase; Lipid Peroxidation; Liver; Male; Malondialdehyde; Oxidation-Reduction; Oxidative Stress; Pancreas; Rats; Rats, Wistar; Streptozocin; Superoxide Dismutase | 2016 |
Pitavastatin Exhibits Protective Effects on Podocytes Accompanied by BMP-7 Up-Regulation and Rho Suppression.
Topics: Animals; Bone Morphogenetic Protein 7; Chemokine CCL2; Creatinine; Diabetes Mellitus, Experimental; Gene Expression; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Intracellular Signaling Peptides and Proteins; Kidney; Male; Malondialdehyde; Membrane Proteins; Nitrates; Nitrites; Protective Agents; Proteinuria; Quinolines; Rats, Wistar; rho-Associated Kinases; Transforming Growth Factor beta; Up-Regulation | 2016 |
Mechanisms of echinochrome potency in modulating diabetic complications in liver.
Topics: Animals; Blood Glucose; Diabetes Complications; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Diet, High-Fat; Islets of Langerhans; Liver Diseases; Liver Function Tests; Male; Malondialdehyde; Naphthoquinones; Oxidative Stress; Rats; Rats, Wistar | 2016 |
Diabetes blocks the cardioprotective effects of sevoflurane postconditioning by impairing Nrf2/Brg1/HO-1 signaling.
Topics: Animals; Apoptosis; Cardiotonic Agents; Cell Line; Diabetes Mellitus, Experimental; DNA Helicases; Heme Oxygenase-1; Ischemic Postconditioning; Male; Malondialdehyde; Methyl Ethers; Mice; Myocardial Ischemia; Myocytes, Cardiac; NF-E2-Related Factor 2; Nuclear Proteins; Sevoflurane; Signal Transduction; Superoxide Dismutase; Superoxides; Transcription Factors | 2016 |
Protective effects of Quercetin and chronic moderate exercise (training) against oxidative stress in the liver tissue of streptozotocin-induced diabetic rats.
Topics: Animals; Antioxidants; Blood Glucose; Cytoprotection; Diabetes Mellitus, Experimental; Lipid Peroxidation; Liver; Male; Malondialdehyde; Oxidative Stress; Physical Conditioning, Animal; Quercetin; Rats; Rats, Wistar; Streptozocin | 2016 |
Antidiabetic and antioxidant effects of saponarin from Gypsophila trichotoma on streptozotocin-induced diabetic normotensive and hypertensive rats.
Topics: Animals; Antioxidants; Apigenin; Blood Glucose; Blood Pressure; Caryophyllaceae; Diabetes Mellitus, Experimental; Glucosides; Glutathione; Glutathione Peroxidase; Glutathione Reductase; Glutathione Transferase; Hypertension; Hypoglycemic Agents; Liver; Male; Malondialdehyde; Molecular Structure; Oxidative Stress; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Streptozocin | 2016 |
An Improvement of Oxidative Stress in Diabetic Rats by Ubiquinone-10 and Ubiquinol-10 and Bioavailability after Short- and Long-Term Coenzyme Q10 Supplementation.
Topics: Animals; Antioxidants; Biological Availability; Blood Glucose; Blood Pressure; Diabetes Mellitus, Experimental; Dietary Supplements; Glucose Tolerance Test; Liver; Male; Malondialdehyde; Oxidative Stress; Pancreas; Rats; Rats, Sprague-Dawley; Ubiquinone | 2016 |
Grapefruit Derived Flavonoid Naringin Improves Ketoacidosis and Lipid Peroxidation in Type 1 Diabetes Rat Model.
Topics: Animals; Blood Glucose; Citrus paradisi; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Flavanones; Glucose Intolerance; Insulin; Ketosis; Lipid Peroxidation; Male; Malondialdehyde; Oxidative Stress; Rats; Rats, Sprague-Dawley | 2016 |
Amelioration of Hyperglycaemia, Oxidative Stress and Dyslipidaemia in Alloxan-Induced Diabetic Wistar Rats Treated with Probiotic and Vitamin C.
Topics: Animals; Antioxidants; Ascorbic Acid; Blood Glucose; Diabetes Mellitus, Experimental; Dyslipidemias; Hyperglycemia; Insulin; Lipid Peroxidation; Male; Malondialdehyde; Oxidative Stress; Probiotics; Random Allocation; Rats; Rats, Wistar | 2016 |
Ethanol extract of Cotinus coggygria leaves accelerates wound healing process in diabetic rats.
Topics: Anacardiaceae; Animals; Diabetes Mellitus, Experimental; Glutathione; Malondialdehyde; Neutrophil Infiltration; Plant Extracts; Plant Leaves; Rats, Wistar; Streptozocin; Wound Healing | 2016 |
The effects of caffeic acid phenethyl ester on streptozotocin-induced diabetic liver injury.
Topics: Animals; Caffeic Acids; Diabetes Mellitus, Experimental; Glutathione; Liver; Male; Malondialdehyde; NF-kappa B; Oxidative Stress; Phenylethyl Alcohol; Rats; Rats, Wistar; Superoxide Dismutase | 2016 |
Evaluation of low-level laser therapy on skeletal muscle ischemia-reperfusion in streptozotocin-induced diabetic rats by assaying biochemical markers and histological changes.
Topics: Animals; Biomarkers; Catalase; Diabetes Mellitus, Experimental; L-Lactate Dehydrogenase; Low-Level Light Therapy; Male; Malondialdehyde; Muscle, Skeletal; Rats; Rats, Wistar; Reperfusion Injury; Streptozocin | 2016 |
[Effect of hydrogen sulfide on oxidative stress and endoplasmic reticulum stress in diabetic cardiomyopathy].
Topics: Animals; Apoptosis; Caspase 12; Diabetes Mellitus, Experimental; Diabetic Cardiomyopathies; Endoplasmic Reticulum Stress; Glutathione Peroxidase; Heat-Shock Proteins; Hydrogen Sulfide; Male; Malondialdehyde; Myocardium; Oxidative Stress; Rats; Streptozocin; Superoxide Dismutase; Transcription Factor CHOP | 2016 |
Chronic intermittent hypobaric hypoxia ameliorates diabetic nephropathy through enhancing HIF1 signaling in rats.
Topics: Animals; Cell Hypoxia; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Diet, High-Fat; Fibrosis; Hypoxia-Inducible Factor 1, alpha Subunit; Kidney; Male; Malondialdehyde; Rats; Rats, Sprague-Dawley; Signal Transduction; Streptozocin; Superoxide Dismutase; Transforming Growth Factor beta1 | 2016 |
The efficacy of Aesculus hippocastanum seeds on diabetic nephropathy in a streptozotocin-induced diabetic rat model.
Topics: Aesculus; Animals; Blood Glucose; Blood Urea Nitrogen; Creatinine; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Disease Models, Animal; Kidney Glomerulus; Male; Malondialdehyde; Plant Extracts; Rats, Sprague-Dawley; Seeds; Streptozocin; Transforming Growth Factor beta; Treatment Outcome | 2016 |
Effects of pomegranate seed oil on oxidative stress markers, serum biochemical parameters and pathological findings in kidney and heart of streptozotocin-induced diabetic rats.
Topics: Animals; Biomarkers; Cardiomyopathies; Creatine Kinase; Diabetes Mellitus, Experimental; Kidney; Kidney Diseases; L-Lactate Dehydrogenase; Lythraceae; Male; Malondialdehyde; Myocardium; Oxidative Stress; Plant Oils; Rats; Rats, Wistar; Seeds; Streptozocin | 2016 |
Oxidative Damage to the Salivary Glands of Rats with Streptozotocin-Induced Diabetes-Temporal Study: Oxidative Stress and Diabetic Salivary Glands.
Topics: 8-Hydroxy-2'-Deoxyguanosine; Aldehydes; Animals; Deoxyguanosine; Diabetes Mellitus, Experimental; Dinoprost; Lipoproteins, LDL; Male; Malondialdehyde; Oxidative Stress; Protein Carbonylation; Rats; Rats, Wistar; Saliva; Salivary Glands; Time Factors | 2016 |
Neuroprotective effect of Cucumis melo Var. flexuosus leaf extract on the brains of rats with streptozotocin-induced diabetes.
Topics: Animals; Blood Glucose; Brain; Caspase 3; Catalase; Cucumis melo; Diabetes Mellitus, Experimental; Dopamine; Interleukins; Lipid Peroxidation; Male; Malondialdehyde; Melatonin; Neuroprotective Agents; Oxidative Stress; Plant Extracts; Plant Leaves; Rats; Rats, Wistar; Superoxide Dismutase; Tumor Necrosis Factor-alpha; Vascular Endothelial Growth Factor A | 2017 |
Effect of gamma-carboxylase inhibition on serum osteocalcin may be partially protective against developing diabetic cardiomyopathy in type 2 diabetic rats.
Topics: Adiponectin; Animals; Apoptosis; Apoptosis Regulatory Proteins; Biomarkers; Blood Glucose; Carbon-Carbon Ligases; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Diabetic Cardiomyopathies; Enzyme Inhibitors; Insulin; Insulin Resistance; Lipids; Male; Malondialdehyde; Myocardium; Osteocalcin; Oxidative Stress; Rats; Receptors, G-Protein-Coupled; Signal Transduction; Warfarin | 2016 |
Lutein attenuates oxidative stress markers and ameliorates glucose homeostasis through polyol pathway in heart and kidney of STZ-induced hyperglycemic rat model.
Topics: Aldehyde Reductase; Animals; Biomarkers; Blood Glucose; Diabetes Mellitus, Experimental; Glucose Tolerance Test; Glutathione; Glutathione Peroxidase; Glutathione Reductase; Heart; Homeostasis; Hyperglycemia; Kidney; L-Iditol 2-Dehydrogenase; Lutein; Male; Malondialdehyde; Oxidative Stress; Polymers; Rats; Rats, Wistar; Reactive Oxygen Species; Superoxide Dismutase; Thiobarbituric Acid Reactive Substances | 2017 |
Effects of Lactobacillus plantarum CCFM0236 on hyperglycaemia and insulin resistance in high-fat and streptozotocin-induced type 2 diabetic mice.
Topics: alpha-Glucosidases; Animals; Antioxidants; Blood Glucose; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Diet, High-Fat; Eating; Insulin Resistance; Interleukin-10; Lactobacillus plantarum; Male; Malondialdehyde; Mice; Mice, Inbred C57BL; Probiotics; Tumor Necrosis Factor-alpha | 2016 |
Pomegranate juice causes a partial improvement through lowering oxidative stress for erectile dysfunction in streptozotocin-diabetic rat.
Topics: Animals; Diabetes Mellitus, Experimental; Erectile Dysfunction; Fruit and Vegetable Juices; Lythraceae; Male; Malondialdehyde; Oxidative Stress; Penile Erection; Rats; Rats, Sprague-Dawley | 2016 |
Effect of photobiomodulation on ischemia/reperfusion-induced renal damage in diabetic rats.
Topics: Acute Kidney Injury; Animals; Catalase; Diabetes Mellitus, Experimental; Glutathione; Kidney Function Tests; Low-Level Light Therapy; Male; Malondialdehyde; Nitric Oxide; Peroxidase; Rats; Rats, Wistar; Reperfusion Injury; Superoxide Dismutase | 2016 |
Protective effect of betulin on cognitive decline in streptozotocin (STZ)-induced diabetic rats.
Topics: Animals; Cognitive Dysfunction; Cytokines; Diabetes Mellitus, Experimental; Disease Models, Animal; Dose-Response Relationship, Drug; Glucose Tolerance Test; Heme Oxygenase-1; Hippocampus; Male; Malondialdehyde; Maze Learning; NF-E2-Related Factor 2; NF-kappa B; Rats; Rats, Sprague-Dawley; Superoxide Dismutase; Triterpenes; Up-Regulation | 2016 |
Fish oil and wheat-germ oil supplementation restores ovarian function in streptozotocin-diabetic rats.
Topics: Animals; Anti-Mullerian Hormone; Antioxidants; Catalase; Diabetes Mellitus, Experimental; Estradiol; Female; Fish Oils; Follicle Stimulating Hormone; Glutathione; Luteinizing Hormone; Malondialdehyde; NF-kappa B; Ovary; Plant Oils; Rats; Reactive Oxygen Species; Superoxide Dismutase | 2017 |
Neuroprotective effects of quercetin on memory and anxiogenic-like behavior in diabetic rats: Role of ectonucleotidases and acetylcholinesterase activities.
Topics: 5'-Nucleotidase; Acetylcholinesterase; Adenosine Deaminase; Animals; Anxiety; Behavior, Animal; Brain; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Dose-Response Relationship, Drug; GPI-Linked Proteins; Male; Malondialdehyde; Maze Learning; Memory; Memory Disorders; Motor Activity; Neuroprotective Agents; Quercetin; Rats, Wistar; Streptozocin | 2016 |
In Vitro Antioxidant activities and anti-diabetic effect of a polysaccharide from Schisandra sphenanthera in rats with type 2 diabetes.
Topics: Animals; Blood Glucose; Catalase; Chromatography, Gel; Chromatography, High Pressure Liquid; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Drug Evaluation, Preclinical; Free Radical Scavengers; Glutathione Peroxidase; Hypoglycemic Agents; Liver; Malondialdehyde; Plant Extracts; Polysaccharides; Rats; Schisandra; Superoxide Dismutase | 2017 |
Effect of dietary supplementation of Padauk (Pterocarpus soyauxii) leaf on high fat diet/streptozotocin induced diabetes in rats' brain and platelets.
Topics: 5'-Nucleotidase; Acetylcholinesterase; Adenosine Deaminase; Animals; Blood Platelets; Brain; Chromatography, High Pressure Liquid; Diabetes Mellitus, Experimental; Diet, High-Fat; Dietary Supplements; Lipid Peroxidation; Male; Malondialdehyde; Phenols; Plant Extracts; Plant Leaves; Pterocarpus; Rats, Wistar; Reactive Oxygen Species; Streptozocin | 2016 |
Activation of ALDH2 with Low Concentration of Ethanol Attenuates Myocardial Ischemia/Reperfusion Injury in Diabetes Rat Model.
Topics: Aldehyde Dehydrogenase, Mitochondrial; Animals; bcl-2-Associated X Protein; Diabetes Mellitus, Experimental; Disease Models, Animal; Enzyme Activation; Ethanol; Heart Ventricles; Hemodynamics; In Vitro Techniques; L-Lactate Dehydrogenase; Male; Malondialdehyde; Myocardial Reperfusion Injury; Myocardium; Myocytes, Cardiac; Perfusion; Rats, Sprague-Dawley; RNA, Messenger; Superoxide Dismutase | 2016 |
Protective effect of Sophoraflavanone G on streptozotocin (STZ)-induced inflammation in diabetic rats.
Topics: Alanine Transaminase; Animals; Aspartate Aminotransferases; Blood Glucose; Carrier Proteins; Cell Cycle Proteins; Diabetes Mellitus, Experimental; Flavanones; I-kappa B Proteins; Inflammation; Insulin; Liver; Male; Malondialdehyde; NF-kappa B; Oxidative Stress; Phosphorylation; Protective Agents; Rats, Sprague-Dawley; Streptozocin; Superoxide Dismutase; Thioredoxins | 2016 |
Changes in rat ovary with experimentally induced diabetes and the effects of lycopene on those changes.
Topics: Animals; Apoptosis; Blood Glucose; Body Weight; Carotenoids; Cell Count; Connexin 43; Corpus Luteum; Diabetes Mellitus, Experimental; Estrous Cycle; Fasting; Female; Immunohistochemistry; Lycopene; Malondialdehyde; Ovarian Follicle; Ovary; Rats, Wistar | 2016 |
Effects of blueberry anthocyanins on retinal oxidative stress and inflammation in diabetes through Nrf2/HO-1 signaling.
Topics: Animals; Anthocyanins; Blood Glucose; Blueberry Plants; Body Weight; Diabetes Mellitus, Experimental; Disease Models, Animal; Glutathione; Glutathione Peroxidase; Heme Oxygenase-1; Inflammation; Interleukin-1beta; Male; Malondialdehyde; NF-E2-Related Factor 2; Oxidative Stress; Rats; Rats, Sprague-Dawley; Retina; Signal Transduction | 2016 |
Effects of Nitrate Intake on Myocardial Ischemia-Reperfusion Injury in Diabetic Rats.
Topics: Animals; Cardiotonic Agents; Coronary Vessels; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Hemodynamics; Lipid Peroxidation; Male; Malondialdehyde; Myocardial Ischemia; Myocardial Reperfusion Injury; Niacinamide; Nitrates; Nitric Oxide; Nitric Oxide Synthase Type III; Rats, Wistar; Real-Time Polymerase Chain Reaction; Reference Values; Reproducibility of Results; Streptozocin; Time Factors; Treatment Outcome | 2016 |
Effects of ferric citrate supplementation on advanced glycation end products in a rat model of streptozotocin/nicotinamide-induced diabetes.
Topics: Animals; Diabetes Mellitus, Experimental; Dietary Supplements; Dose-Response Relationship, Drug; Fatty Liver; Ferric Compounds; Glutathione; Glycation End Products, Advanced; Heme Oxygenase-1; Lipid Peroxidation; Liver; Male; Malondialdehyde; NF-kappa B; Niacinamide; p38 Mitogen-Activated Protein Kinases; Rats; Rats, Wistar; Streptozocin; Triglycerides | 2017 |
Selenium Nanoparticles Attenuate Oxidative Stress and Testicular Damage in Streptozotocin-Induced Diabetic Rats.
Topics: Animals; Antioxidants; Apoptosis; Biomarkers; Diabetes Mellitus, Experimental; Glutathione; Lipid Peroxidation; Male; Malondialdehyde; Nanoparticles; Nitric Oxide; Oxidation-Reduction; Oxidative Stress; Proliferating Cell Nuclear Antigen; Rats; Selenium; Testis | 2016 |
2-Morpholino-5-Phenyl-6H-1,3,4-Thiadiazine Corrects Metabolic Disorders during the Development of Alloxan Diabetes Mellitus in Rats.
Topics: Alloxan; Animals; Animals, Outbred Strains; Blood Glucose; Catalase; Diabetes Mellitus, Experimental; Glycated Hemoglobin; Hypoglycemic Agents; Injections, Intramuscular; Male; Malondialdehyde; Morpholines; Peroxidase; Rats; Thiadiazines | 2016 |
Small Molecule Inhibiting Nuclear Factor-kB Ameliorates Oxidative Stress and Suppresses Renal Inflammation in Early Stage of Alloxan-Induced Diabetic Nephropathy in Rat.
Topics: Alloxan; Animals; Antioxidants; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Dose-Response Relationship, Drug; Glomerular Filtration Rate; Glutathione; Inflammation; Kidney; Male; Malondialdehyde; NF-kappa B; Oxidative Stress; Rats; Rats, Wistar; Stilbenes; Superoxide Dismutase | 2017 |
Leaf Extract from Lithocarpus polystachyus Rehd. Promote Glycogen Synthesis in T2DM Mice.
Topics: Amino Acid Isomerases; Animals; Blood Glucose; Body Weight; Cells, Cultured; Diabetes Mellitus, Experimental; Down-Regulation; Fagaceae; Glucose Tolerance Test; Glutathione; Glycogen; Hypoglycemic Agents; Insulin; Liver; Male; Malondialdehyde; Mice; Plant Extracts; Plant Leaves; Streptozocin; Superoxide Dismutase; Up-Regulation | 2016 |
Sericin ameliorated dysmorphic mitochondria in high-cholesterol diet/streptozotocin rat by antioxidative property.
Topics: Animals; Antioxidants; Blood Glucose; Bombyx; Cholesterol; Diabetes Mellitus, Experimental; Diet, High-Fat; Endoplasmic Reticulum; Fatty Liver; Female; Hypercholesterolemia; Kidney; Liver; Malondialdehyde; Mitochondria; Myocardium; Oxidative Stress; Pancreas; Rats; Rats, Wistar; Reactive Oxygen Species; Sericins; Streptozocin | 2017 |
Fish oil and wheat germ oil supplementation modulates brain injury in streptozotocin-induced diabetic rats.
Topics: Animals; Brain Injuries; Catalase; Diabetes Mellitus, Experimental; Dietary Supplements; Fish Oils; Glutathione; Glutathione Disulfide; Inflammation Mediators; Lipid Peroxidation; Male; Malondialdehyde; Nitric Oxide; Plant Oils; Rats, Wistar; Superoxide Dismutase | 2017 |
Diosgenin ameliorates development of neuropathic pain in diabetic rats: Involvement of oxidative stress and inflammation.
Topics: Animals; Antioxidants; Blood Glucose; Diabetes Mellitus, Experimental; Diabetic Neuropathies; Diosgenin; Ganglia, Spinal; Inflammation; Male; Malondialdehyde; Neuralgia; NF-kappa B; Oxidative Stress; Rats; Rats, Wistar; Sciatic Nerve; Streptozocin; Superoxide Dismutase | 2017 |
Brief Communication: Plasma lipid oxidation predicts atherosclerotic status better than cholesterol in diabetic apolipoprotein E deficient mice.
Topics: Animals; Aorta; Apolipoproteins E; Cholesterol; Diabetes Mellitus, Experimental; Enalapril; Lipid Metabolism; Lipids; Lipoproteins, HDL; Lipoproteins, LDL; Male; Malondialdehyde; Mice, Knockout; Oxidation-Reduction; Plaque, Atherosclerotic | 2017 |
Sustained kidney biochemical derangement in treated experimental diabetes: a clue to metabolic memory.
Topics: Adenylate Kinase; Animals; Blood Glucose; Diabetes Mellitus, Experimental; DNA, Mitochondrial; Fasting; Fumarates; Hyperglycemia; Kidney; Male; Malondialdehyde; Mitochondria; Models, Biological; Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha; Phosphorylation; Rats, Wistar; Transforming Growth Factor beta | 2017 |
Anti-diabetic effects of Inonotus obliquus polysaccharides-chromium (III) complex in type 2 diabetic mice and its sub-acute toxicity evaluation in normal mice.
Topics: Animals; Basidiomycota; Blood Glucose; Body Weight; Chromium; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Heart; Hypoglycemic Agents; Kidney; Liver; Male; Malondialdehyde; Mice; Organ Size; Pancreas; Polysaccharides; Spleen; Thymus Gland | 2017 |
Protective effect of butin against ischemia/reperfusion-induced myocardial injury in diabetic mice: involvement of the AMPK/GSK-3β/Nrf2 signaling pathway.
Topics: Adenylate Kinase; Animals; Antioxidants; Apoptosis; Benzopyrans; Cardiotonic Agents; Diabetes Mellitus, Experimental; Glycogen Synthase Kinase 3 beta; Malondialdehyde; Mice; Myocardial Reperfusion Injury; Myocardium; NF-E2-Related Factor 2; Phosphorylation; Proto-Oncogene Proteins c-akt; Reactive Oxygen Species; Signal Transduction; Superoxide Dismutase; Up-Regulation | 2017 |
Antidiabetic and Antioxidant Potentials of Amaranthus hybridus in Streptozotocin-Induced Diabetic Rats.
Topics: Amaranthus; Animals; Antioxidants; Blood Glucose; Catalase; Diabetes Mellitus, Experimental; Female; Glutathione; Hypoglycemic Agents; India; Kidney; Liver; Male; Malondialdehyde; Oxidative Stress; Phytotherapy; Plant Extracts; Plant Leaves; Rats; Rats, Wistar; Superoxide Dismutase | 2017 |
Crocin improves spatial learning and memory deficits in the Morris water maze via attenuating cortical oxidative damage in diabetic rats.
Topics: Animals; Blood Glucose; Carotenoids; Cerebral Cortex; Diabetes Mellitus, Experimental; Free Radical Scavengers; Lipid Peroxidation; Male; Malondialdehyde; Memory Disorders; Oxidative Stress; Rats; Rats, Wistar; Spatial Learning; Spatial Memory; Sulfhydryl Compounds; Treatment Outcome | 2017 |
Inhibition of dynamin-related protein 1 protects against myocardial ischemia-reperfusion injury in diabetic mice.
Topics: Animals; Apoptosis; Cardiovascular Agents; Diabetes Mellitus, Experimental; Diet, High-Fat; Dynamins; L-Lactate Dehydrogenase; Male; Malondialdehyde; Mice, Inbred C57BL; Mitochondria, Heart; Mitochondrial Dynamics; Myocardial Infarction; Myocardial Reperfusion Injury; Myocytes, Cardiac; Oxidative Stress; Quinazolinones; Signal Transduction; Streptozocin; Superoxide Dismutase; Troponin I | 2017 |
Antioxidant treatment ameliorates diabetes-induced dysfunction of the vas deferens in a rat model.
Topics: Animals; Antioxidants; Antipyrine; Diabetes Mellitus, Experimental; Edaravone; Male; Malondialdehyde; Oxidative Stress; Rats; Rats, Wistar; Taurine; Vas Deferens | 2018 |
Chronic Administration of Rosa canina Hydro-Alcoholic Extract Attenuates Depressive-Like Behavior and Recognition Memory Impairment in Diabetic Mice: A Possible Role of Oxidative Stress.
Topics: Animals; Behavior, Animal; Brain; Depression; Diabetes Mellitus, Experimental; Dose-Response Relationship, Drug; Male; Malondialdehyde; Memory Disorders; Mice; Oxidative Stress; Plant Extracts; Random Allocation; Rosa; Streptozocin; Weight Gain | 2017 |
Protective effect of crocin and voluntary exercise against oxidative stress in the heart of high-fat diet-induced type 2 diabetic rats.
Topics: Animals; Antioxidants; Carotenoids; Catalase; Combined Modality Therapy; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Diabetic Cardiomyopathies; Diet, High-Fat; Exercise Therapy; Glutathione Peroxidase; Lipid Peroxidation; Male; Malondialdehyde; Myocardium; Oxidative Stress; Rats, Wistar; Streptozocin; Superoxide Dismutase | 2016 |
Beneficial effects of deep sea fish oil on diabetic mice neurological injury.
Topics: Animals; Antioxidants; Behavior, Animal; Brain; Diabetes Mellitus, Experimental; Fish Oils; Male; Malondialdehyde; Memory; Mice; Oxidative Stress; Streptozocin | 2017 |
Chronic administration of atorvastatin could partially ameliorate erectile function in streptozotocin-induced diabetic rats.
Topics: Administration, Intravenous; Animals; Arterial Pressure; Atorvastatin; Diabetes Mellitus, Experimental; Erectile Dysfunction; Male; Malondialdehyde; Penile Erection; Pyrimidines; Rats; Rats, Sprague-Dawley; Sulfonamides; Superoxide Dismutase | 2017 |
Effects of the TLR4 signaling pathway on apoptosis of neuronal cells in diabetes mellitus complicated with cerebral infarction in a rat model.
Topics: Animals; Apoptosis; Apoptosis Regulatory Proteins; Brain; Diabetes Mellitus, Experimental; Infarction, Middle Cerebral Artery; Interleukin-1beta; Male; Malondialdehyde; Neurons; Rats, Sprague-Dawley; Signal Transduction; Superoxide Dismutase; Toll-Like Receptor 4; Tumor Necrosis Factor-alpha | 2017 |
Elevated lipid peroxidation and DNA oxidation in nerve from diabetic rats: effects of aldose reductase inhibition, insulin, and neurotrophic factors.
Topics: Aldehyde Reductase; Animals; Blood Glucose; Body Weight; Diabetes Mellitus, Experimental; Diabetic Neuropathies; DNA; Enzyme Inhibitors; Female; Galactitol; Galactose; Hydrazones; Hypoglycemic Agents; Insulin; Lipid Peroxidation; Malondialdehyde; Nerve Growth Factors; Neurons; Nitroparaffins; Oxidation-Reduction; Rats; Rats, Sprague-Dawley; Sulfones | 2008 |
Melatonin treatment against remote organ injury induced by renal ischemia reperfusion injury in diabetes mellitus.
Topics: Alanine Transaminase; Animals; Antioxidants; Aspartate Aminotransferases; Catalase; Diabetes Mellitus, Experimental; Kidney; Liver; Liver Diseases; Male; Malondialdehyde; Melatonin; Nitric Oxide; Oxidative Stress; Peroxidase; Protein Carbonylation; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Superoxide Dismutase; Xanthine Oxidase | 2008 |
Early lipoic acid intake protects retina of diabetic mice.
Topics: Animals; Antioxidants; Diabetes Mellitus, Experimental; Diabetic Retinopathy; Drug Administration Schedule; Electroretinography; Glutathione; Glutathione Peroxidase; Hypoglycemic Agents; Insulin; Male; Malondialdehyde; Mice; Oxidative Stress; Retina; Thioctic Acid | 2008 |
The neuroprotective effect of fish n-3 fatty acids in the hippocampus of diabetic rats.
Topics: Animals; Apoptosis; Catalase; Diabetes Mellitus, Experimental; Diet; Fatty Acids, Omega-3; Fish Oils; Hippocampus; Male; Malondialdehyde; Neurons; Neuroprotective Agents; Oxidative Stress; Rats; Rats, Sprague-Dawley; Superoxide Dismutase | 2008 |
Lutein prevents cataract development and progression in diabetic rats.
Topics: Animals; Blood Glucose; Body Weight; Cataract; Diabetes Mellitus, Experimental; Diabetic Retinopathy; Disease Models, Animal; Disease Progression; Drug Therapy, Combination; Glutathione; Glutathione Peroxidase; Glycated Hemoglobin; Hypoglycemic Agents; Insulin; Lipid Peroxidation; Lutein; Male; Malondialdehyde; Oxidative Stress; Rats; Rats, Wistar | 2009 |
Therapeutic effects of Teucrium polium extract on oxidative stress in pancreas of streptozotocin-induced diabetic rats.
Topics: Animals; Antioxidants; Blood Glucose; Body Weight; Diabetes Mellitus, Experimental; Lipid Peroxidation; Malondialdehyde; Nitric Oxide; Oxidative Stress; Pancreas; Phenols; Phytotherapy; Plant Extracts; Protein Carbonylation; Rats; Reactive Oxygen Species; Streptozocin; Teucrium | 2008 |
Effects of nitrosative stress and reactive oxygen-scavenging systems in esophageal physiopathy under streptozotocin-induced experimental hyperglycemia.
Topics: Animals; Arginine; Diabetes Mellitus, Experimental; Disease Models, Animal; Esophagus; Glutathione Peroxidase; Glycosylation; Hyperglycemia; Indomethacin; Lipid Peroxidation; Male; Malondialdehyde; Mucous Membrane; Nitric Oxide; Nitrosation; Oxidative Stress; Rats; Rats, Wistar; Reactive Oxygen Species; Streptozocin | 2008 |
[Protective effect of nourishingyin and promoting blood flow recipe on kidney of diabetic rat].
Topics: Animals; Blotting, Western; Diabetes Mellitus, Experimental; Drugs, Chinese Herbal; Immunohistochemistry; Kidney; Male; Malondialdehyde; Nitric Oxide Synthase Type II; Random Allocation; Rats; Rats, Sprague-Dawley; Reverse Transcriptase Polymerase Chain Reaction; Superoxide Dismutase; Tyrosine | 2008 |
[Effects of huanglian jiedu decoction on the oxidative stress of liver mitochondria in insulin resistant Rats].
Topics: Animals; Blood Glucose; Diabetes Mellitus, Experimental; Drugs, Chinese Herbal; Glutathione Peroxidase; Insulin; Insulin Resistance; Male; Malondialdehyde; Mitochondria, Liver; Oxidative Stress; Random Allocation; Rats; Rats, Wistar | 2008 |
Lutein prevents the effect of high glucose levels on immune system cells in vivo and in vitro.
Topics: Animals; Antioxidants; Biomarkers; Blood Glucose; Cell Line; Diabetes Mellitus, Experimental; Glutathione; Humans; Immune System; Leukocytes, Mononuclear; Lutein; Malondialdehyde; NF-kappa B; Oxidation-Reduction; Oxidative Stress; Rats | 2008 |
Effects of cyclooxygenase-2 gene inactivation on cardiac autonomic and left ventricular function in experimental diabetes.
Topics: Animals; Blood Glucose; Body Weight; Collagen; Cyclooxygenase 2; Diabetes Mellitus, Experimental; Echocardiography, Doppler; Gene Silencing; Glutathione; Heart; Heart Rate; Inflammation Mediators; Male; Malondialdehyde; Mice; Mice, Knockout; Myocardial Contraction; Myocardium; Oxidative Stress; Prostaglandins; Stroke Volume; Sympathetic Nervous System; Time Factors; Tumor Necrosis Factor-alpha; Ventricular Dysfunction, Left; Ventricular Function, Left | 2009 |
[Effects of lisinopril on diabetic peripheral neuropathy: experiment with rats].
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Diabetes Mellitus, Experimental; Diabetic Neuropathies; Lisinopril; Male; Malondialdehyde; Peroneal Nerve; Rats; Rats, Wistar; Sciatic Nerve; Sodium-Potassium-Exchanging ATPase; Superoxide Dismutase | 2008 |
Effect of thymoquinone on malformations and oxidative stress-induced diabetic mice.
Topics: Animals; Antioxidants; Benzoquinones; Congenital Abnormalities; Cricetinae; Diabetes Mellitus, Experimental; Female; Glutathione; Liver; Malondialdehyde; Mice; Models, Biological; Oxidative Stress; Pregnancy; Pregnancy, Animal | 2007 |
Aucubin prevents loss of hippocampal neurons and regulates antioxidative activity in diabetic encephalopathy rats.
Topics: Animals; Antioxidants; Brain Diseases; Cognition Disorders; Diabetes Mellitus, Experimental; Glucosides; Hippocampus; Iridoid Glucosides; Iridoids; Lipid Peroxides; Male; Malondialdehyde; Neurons; Neuroprotective Agents; Nitric Oxide Synthase; Rats; Rats, Wistar | 2009 |
Pleiotropic effect of pyridoxamine on diabetic complications via CD36 expression in KK-Ay/Ta mice.
Topics: Adipose Tissue; Animals; CD36 Antigens; Diabetes Complications; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Drug Evaluation, Preclinical; Gene Expression Regulation; Hypoglycemic Agents; Insulin Resistance; Kidney; Lipid Peroxidation; Male; Malondialdehyde; Mice; Mice, Inbred C57BL; Mice, Mutant Strains; Pyridoxamine | 2009 |
Breviscapine, a traditional Chinese medicine, alleviates myocardial ischaemia reperfusion injury in diabetic rats.
Topics: Adenosine Triphosphatases; Animals; Diabetes Mellitus, Experimental; Flavonoids; Glutathione Peroxidase; Immunohistochemistry; Intercellular Adhesion Molecule-1; Malondialdehyde; Myocardial Reperfusion Injury; Myocardium; Myocytes, Cardiac; Oxidative Stress; Rats; Rats, Sprague-Dawley; Superoxide Dismutase | 2008 |
Antioxidant activity of chito-oligosaccharides on pancreatic islet cells in streptozotocin-induced diabetes in rats.
Topics: Animals; Antioxidants; Cell Line; Chitin; Chitosan; Diabetes Mellitus, Experimental; Glutathione Peroxidase; Insulin-Secreting Cells; Islets of Langerhans; Male; Malondialdehyde; Metformin; Mice; Mice, Inbred NOD; Oligosaccharides; Rats; Rats, Wistar; Streptozocin; Superoxide Dismutase | 2009 |
Protective effect of berberine on beta cells in streptozotocin- and high-carbohydrate/high-fat diet-induced diabetic rats.
Topics: Animals; Berberine; Body Weight; Diabetes Mellitus, Experimental; Dietary Carbohydrates; Dietary Fats; Eosine Yellowish-(YS); Hematoxylin; Insulin; Insulin-Secreting Cells; Male; Malondialdehyde; Microscopy, Electron, Transmission; Rats; Rats, Wistar; Reference Standards; Staining and Labeling; Streptozocin; Superoxide Dismutase | 2009 |
B vitamins alleviate indices of neuropathic pain in diabetic rats.
Topics: Aldehydes; Animals; Blood Glucose; Diabetes Mellitus, Experimental; Diabetic Neuropathies; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Drug Therapy, Combination; Female; Formaldehyde; Hyperalgesia; Malondialdehyde; Neural Conduction; Rats; Rats, Sprague-Dawley; Streptozocin; Touch; Vitamin B Complex | 2009 |
Beneficial effects of Chinese prescription Kangen-karyu on diabetes associated with hyperlipidemia, advanced glycation endproducts, and oxidative stress in streptozotocin-induced diabetic rats.
Topics: Animals; Antioxidants; Blood Glucose; Cholesterol; Cyclooxygenase 2; Diabetes Mellitus, Experimental; Drugs, Chinese Herbal; Glycation End Products, Advanced; Hypertriglyceridemia; Hypoglycemic Agents; Hypolipidemic Agents; Liver; Lysine; Magnoliopsida; Male; Malondialdehyde; NF-kappa B; Nitric Oxide Synthase Type II; Oxidative Stress; Phytotherapy; Plants, Medicinal; Rats; Rats, Wistar; Triglycerides | 2009 |
Antihyperglycemic, antioxidant and antiglycation activities of mulberry leaf extract in streptozotocin-induced chronic diabetic rats.
Topics: Animals; Antioxidants; Blood Glucose; Diabetes Mellitus, Experimental; Glycated Hemoglobin; Hypoglycemic Agents; Lipid Peroxides; Male; Malondialdehyde; Morus; Phytotherapy; Plant Extracts; Plant Leaves; Rats; Rats, Sprague-Dawley | 2009 |
Improvement of neovascularization capacity of bone marrow mononuclear cells from diabetic mice by ex vivo pretreatment with resveratrol.
Topics: Animals; Antioxidants; Blood Pressure; Body Weight; Bone Marrow Cells; Capillaries; Diabetes Mellitus, Experimental; Heart Rate; Hindlimb; Ischemia; Laser-Doppler Flowmetry; Malondialdehyde; Mice; Mice, Inbred C57BL; Monocytes; Neovascularization, Physiologic; Nitric Oxide Synthase Type III; Oxidative Stress; Reactive Oxygen Species; Receptors, Vascular Endothelial Growth Factor; Regional Blood Flow; Resveratrol; Reverse Transcriptase Polymerase Chain Reaction; Stilbenes; Superoxide Dismutase; Vascular Endothelial Growth Factor A | 2009 |
Assessment of genomic instability in normal and diabetic rats treated with metformin.
Topics: Animals; Chromosome Aberrations; Diabetes Mellitus, Experimental; Drug Administration Schedule; Genomic Instability; Glutathione; Hypoglycemic Agents; Lipid Peroxidation; Male; Malondialdehyde; Metformin; Micronuclei, Chromosome-Defective; Mitosis; Oxidative Stress; Rats; Rats, Wistar; Reactive Oxygen Species; Sperm Motility; Spermatozoa | 2009 |
Depressive status does not alter renal oxidative and immunological parameters during early diabetic nephropathy in rats.
Topics: Animals; Cytokines; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Fluorescent Antibody Technique; Glutathione; Kidney; Lipid Peroxidation; Macrophages; Male; Malondialdehyde; Monocytes; Motivation; Motor Activity; Oxidative Stress; Psychoneuroimmunology; Rats; Rats, Sprague-Dawley; Receptor for Advanced Glycation End Products; Receptors, Immunologic; Superoxides | 2009 |
The Cohen diabetic rat as a model for fetal growth restriction: vitamins C and E reduce fetal oxidative stress but do not restore normal growth.
Topics: Animals; Animals, Outbred Strains; Antioxidants; Ascorbic Acid; Catalase; Copper; Diabetes Mellitus, Experimental; Diet; Female; Fetal Growth Retardation; Lipid Peroxidation; Malondialdehyde; Models, Animal; Organ Size; Oxidation-Reduction; Oxidative Stress; Rats; Rats, Inbred Strains; Rats, Wistar; Sucrose; Superoxide Dismutase; Vitamin E | 2009 |
Gastroprotective effects of the insulin sensitizers rosiglitazone and metformin against indomethacin-induced gastric ulcers in Type 2 diabetic rats.
Topics: Animals; Catalase; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Dinoprostone; Gastric Mucosa; Hypoglycemic Agents; Indomethacin; Male; Malondialdehyde; Metformin; Mucins; Nitric Oxide; Rats; Rats, Wistar; Rosiglitazone; Stomach Ulcer; Thiazolidinediones | 2010 |
Effects of blood glucose fluctuation on skin biophysical properties, structure and antioxidant status in an animal model.
Topics: Animals; Blood Glucose; Body Water; Diabetes Mellitus, Experimental; Elasticity; Glucose; Glycation End Products, Advanced; Hydroxyproline; Male; Malondialdehyde; Mice; Skin | 2010 |
Effects of chromium histidinate on renal function, oxidative stress, and heat-shock proteins in fat-fed and streptozotocin-treated rats.
Topics: Animals; Chaperonin 60; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Dietary Fats; Dinoprost; Heat-Shock Proteins; Histidine; HSP70 Heat-Shock Proteins; Kidney; Lipid Peroxidation; Male; Malondialdehyde; Organometallic Compounds; Oxidative Stress; Rats; Rats, Wistar | 2010 |
Evaluation of DNA damage and metabolic syndrome parameters in diabetic rabbits supplemented with antioxidants.
Topics: Animals; Antioxidants; Ascorbic Acid; Blood Glucose; Comet Assay; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; DNA Damage; Lipid Peroxidation; Lymphocytes; Male; Malondialdehyde; Oxidative Stress; Rabbits; Vitamin E | 2009 |
Effects of angiotensin receptor blocker on oxidative stress and cardio-renal function in streptozotocin-induced diabetic rats.
Topics: Angiotensin II Type 1 Receptor Blockers; Animals; Blood Urea Nitrogen; Blotting, Western; Cardiomyopathies; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Fibrosis; Heart; Kidney; Lipid Peroxidation; Losartan; Male; Malondialdehyde; Myocardium; Oxidative Stress; Proteinuria; Rats; Rats, Sprague-Dawley; Streptozocin | 2009 |
Chymase inhibition provides pancreatic islet protection in hamsters with streptozotocin-induced diabetes.
Topics: Angiotensin II; Animals; Blood Glucose; Chymases; Cricetinae; Diabetes Mellitus, Experimental; Islets of Langerhans; Male; Malondialdehyde; Peptidyl-Dipeptidase A; Streptozocin; Sulfonamides; Thiophenes; Time Factors | 2009 |
Effect of chromium supplementation on the diabetes induced-oxidative stress in liver and brain of adult rats.
Topics: Alloxan; Animals; Brain; Catalase; Chromium; Diabetes Mellitus; Diabetes Mellitus, Experimental; Disease Models, Animal; DNA; Glutathione Peroxidase; Glycemic Index; Humans; Lipid Peroxidation; Liver; Male; Malondialdehyde; Oxidative Stress; Oxidoreductases; Picolinic Acids; Rats; Rats, Wistar; RNA; Superoxide Dismutase | 2009 |
Supplementation with magnesium and vitamin E were more effective than magnesium alone to decrease plasma lipids and blood viscosity in diabetic rats.
Topics: Animals; Antioxidants; Blood Viscosity; Cholesterol; Diabetes Mellitus, Experimental; Diet; Dietary Supplements; Dose-Response Relationship, Drug; Drug Therapy, Combination; Female; Hypolipidemic Agents; Lipids; Magnesium; Male; Malondialdehyde; Rats; Rats, Wistar; Vitamin E | 2009 |
Effects of total glucosides of paeony on oxidative stress in the kidney from diabetic rats.
Topics: Albuminuria; Animals; Antioxidants; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Dose-Response Relationship, Drug; Drugs, Chinese Herbal; Glucosides; Kidney; Male; Malondialdehyde; NF-kappa B; Oxidative Stress; p38 Mitogen-Activated Protein Kinases; Paeonia; Phytotherapy; Rats; Rats, Wistar | 2010 |
Mulberry leaf extract restores arterial pressure in streptozotocin-induced chronic diabetic rats.
Topics: Animals; Blood Glucose; Blood Pressure; Body Weight; Chronic Disease; Diabetes Mellitus, Experimental; Heart Rate; Insulin; Lipid Peroxidation; Male; Malondialdehyde; Morus; Phytotherapy; Plant Extracts; Plant Leaves; Rats; Rats, Sprague-Dawley; Reference Values; Vasoconstriction; Vasoconstrictor Agents; Vasodilation; Vasodilator Agents | 2009 |
Protective effects of vitamin E on central nervous system in streptozotocin-induced diabetic rats.
Topics: Animals; Catalase; Central Nervous System; Diabetes Mellitus, Experimental; Glutathione Peroxidase; Male; Malondialdehyde; Oxidative Stress; Rats; Rats, Wistar; Superoxide Dismutase; Vitamin E | 2009 |
In vivo antioxidative activity of a quantified Pueraria lobata root extract.
Topics: alpha-Tocopherol; Animals; Antioxidants; Blood Glucose; Body Weight; Diabetes Mellitus, Experimental; Drugs, Chinese Herbal; gamma-Tocopherol; Isoflavones; Lipid Peroxidation; Male; Malondialdehyde; Oxidative Stress; Plant Extracts; Plant Roots; Pueraria; Rats; Rats, Wistar; Ubiquinone | 2010 |
Cardioprotective actions of two bioflavonoids, quercetin and rutin, in experimental myocardial infarction in both normal and streptozotocin-induced type I diabetic rats.
Topics: Animals; Cardiotonic Agents; Catalase; Diabetes Mellitus, Experimental; Electrocardiography; Female; Heart; Male; Malondialdehyde; Myocardial Infarction; Myocardium; Quercetin; Rats; Rats, Wistar; Rutin; Streptozocin; Superoxide Dismutase | 2009 |
Oral supplementation of catalpol ameliorates diabetic encephalopathy in rats.
Topics: Administration, Oral; Animals; Behavior, Animal; Blood Glucose; Body Weight; Catalase; Diabetes Mellitus, Experimental; Diabetic Neuropathies; Dietary Supplements; Disease Models, Animal; Dose-Response Relationship, Drug; Enzyme-Linked Immunosorbent Assay; Glucosides; Glutathione Peroxidase; In Situ Nick-End Labeling; Iridoid Glucosides; Iridoids; Lipid Peroxidation; Male; Malondialdehyde; Maze Learning; Nerve Growth Factor; Oxidative Stress; Rats; Rats, Sprague-Dawley; Superoxide Dismutase; Time Factors | 2010 |
Beneficial effect of docosahexanoic acid and lutein on retinal structural, metabolic, and functional abnormalities in diabetic rats.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Antioxidants; Apoptosis; Biomarkers; Blood Glucose; Caspase 3; Diabetes Mellitus, Experimental; Diabetic Retinopathy; Docosahexaenoic Acids; Drug Therapy, Combination; Electroretinography; Enzyme-Linked Immunosorbent Assay; Fluorescent Antibody Technique, Indirect; Glutathione; Glutathione Peroxidase; In Situ Nick-End Labeling; Insulin; Lutein; Male; Malondialdehyde; Oxidative Stress; Rats; Rats, Wistar; Retina; Tyrosine | 2009 |
Mangiferin prevents diabetic nephropathy progression in streptozotocin-induced diabetic rats.
Topics: Albuminuria; Animals; Blood Glucose; Cell Proliferation; Cells, Cultured; Collagen Type IV; Creatinine; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Glutathione Peroxidase; Glycation End Products, Advanced; Hypoglycemic Agents; Male; Malondialdehyde; Mangifera; Mesangial Cells; Rats; Rats, Wistar; Sorbitol; Superoxide Dismutase; Transforming Growth Factor beta1; Xanthones | 2010 |
Chronic treatment of silymarin improves hyperalgesia and motor nerve conduction velocity in diabetic neuropathic rat.
Topics: Animals; Antioxidants; Diabetes Mellitus, Experimental; Diabetic Neuropathies; Hyperalgesia; Male; Malondialdehyde; Neural Conduction; Oxidative Stress; Rats; Rats, Wistar; Silymarin; Sodium Salicylate; Superoxide Dismutase | 2010 |
Mechanisms underlying vascular effect of chronic resveratrol in streptozotocin-diabetic rats.
Topics: Administration, Oral; Animals; Aorta; Diabetes Mellitus, Experimental; Endothelium, Vascular; Hypoglycemic Agents; Lipid Peroxidation; Liver; Male; Malondialdehyde; Muscle, Smooth, Vascular; Rats; Rats, Wistar; Resveratrol; Stilbenes; Superoxide Dismutase; Vasoconstrictor Agents | 2010 |
Lutein and docosahexaenoic acid prevent cortex lipid peroxidation in streptozotocin-induced diabetic rat cerebral cortex.
Topics: Aldehydes; Animals; Antigens, Nuclear; Antioxidants; Biomarkers; Brain Diseases, Metabolic; Cerebral Cortex; Diabetes Complications; Diabetes Mellitus, Experimental; Disease Models, Animal; Docosahexaenoic Acids; Drug Therapy, Combination; Fluorescent Antibody Technique; Glucose; Glutathione; Glutathione Peroxidase; Hyperglycemia; Insulin; Lipid Peroxidation; Lutein; Male; Malondialdehyde; Nerve Tissue Proteins; Oxidative Stress; Rats; Rats, Wistar; Treatment Outcome | 2010 |
[Effects of angrographolide on plasma glucose level of experiment diabetic rats and its molecular mechanism].
Topics: Andrographis; Animals; Blood Glucose; Diabetes Mellitus, Experimental; Female; Hypoglycemic Agents; Immunohistochemistry; Insulin; Lactones; Male; Malondialdehyde; Proto-Oncogene Proteins c-bcl-2; Random Allocation; Rats; Rats, Sprague-Dawley; Streptozocin; Superoxide Dismutase | 2009 |
Comparison of vitamin E, L-carnitine and melatonin in ameliorating carbon tetrachloride and diabetes induced hepatic oxidative stress.
Topics: Animals; Antioxidants; Blood Glucose; Carbon Tetrachloride Poisoning; Carnitine; Chemical and Drug Induced Liver Injury; Diabetes Mellitus, Experimental; Glutathione; Male; Malondialdehyde; Melatonin; Oxidative Stress; Rats; Rats, Wistar; Superoxide Dismutase; Vitamin E | 2009 |
Cardiac protection by basic fibroblast growth factor from ischemia/reperfusion-induced injury in diabetic rats.
Topics: Animals; Antioxidants; Caspase 3; Cell Death; Diabetes Mellitus, Experimental; Dietary Supplements; Fibroblast Growth Factor 2; Heart; L-Lactate Dehydrogenase; Male; Malondialdehyde; Myocardial Infarction; Myocardium; Oxidative Stress; Rats; Rats, Sprague-Dawley; Reperfusion Injury | 2010 |
Hypoglycemic and insulin-sensitizing effects of berberine in high-fat diet- and streptozotocin-induced diabetic rats.
Topics: Adiponectin; Animals; Berberine; Blood Glucose; C-Reactive Protein; Cholesterol; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Dietary Fats; Glucose Tolerance Test; Glutathione; Hypoglycemic Agents; Insulin; Insulin Resistance; Leptin; Liver; Male; Malondialdehyde; Oxidative Stress; Rats; Rats, Sprague-Dawley; Superoxide Dismutase; Tumor Necrosis Factor-alpha | 2011 |
Phytochemical characteristics and hypoglycaemic activity of fraction from mushroom Inonotus obliquus.
Topics: Agaricales; alpha-Amylases; Animals; Antioxidants; Biological Products; Blood Glucose; Cholesterol, HDL; Diabetes Mellitus, Experimental; Glutathione Peroxidase; Glycogen; Hypoglycemic Agents; Liver; Male; Malondialdehyde; Mice; Mice, Inbred Strains; Triglycerides | 2010 |
Beneficial effects of the ethanol extract from the dry matter of a culture broth of Inonotus obliquus in submerged culture on the antioxidant defence system and regeneration of pancreatic beta-cells in experimental diabetes in mice.
Topics: Animals; Antioxidants; Basidiomycota; Biological Products; Catalase; Chromatography, High Pressure Liquid; Diabetes Mellitus, Experimental; Drug Evaluation, Preclinical; Glutathione Peroxidase; Glycogen; Hypoglycemic Agents; Insulin; Insulin-Secreting Cells; Lipid Peroxidation; Lipids; Liver; Male; Malondialdehyde; Mice; Mice, Inbred ICR; Pancreas; Regeneration; Superoxide Dismutase | 2010 |
Antioxidant protection of Malaysian tualang honey in pancreas of normal and streptozotocin-induced diabetic rats.
Topics: Animals; Antioxidants; Blood Glucose; Catalase; Diabetes Mellitus, Experimental; Glutathione Peroxidase; Glutathione Reductase; Glutathione Transferase; Honey; Lipid Peroxidation; Male; Malondialdehyde; Pancreas; Rats; Rats, Sprague-Dawley; Superoxide Dismutase; Up-Regulation | 2010 |
Effects of 4-phenylbutyric acid on the process and development of diabetic nephropathy induced in rats by streptozotocin: regulation of endoplasmic reticulum stress-oxidative activation.
Topics: Animals; Antioxidants; Blood Urea Nitrogen; Creatinine; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Endoplasmic Reticulum; Hydroxyproline; Kidney; Male; Malondialdehyde; NADPH Oxidases; Oxidative Stress; Phenylbutyrates; Proteinuria; Rats; Rats, Sprague-Dawley; Superoxide Dismutase | 2010 |
N-acetyl cysteine promotes angiogenesis and clearance of free oxygen radicals, thus improving wound healing in an alloxan-induced diabetic mouse model of incisional wound.
Topics: Acetylcysteine; Alloxan; Animals; Diabetes Mellitus, Experimental; Disease Models, Animal; Free Radical Scavengers; Glutathione; Hydroxyproline; Male; Malondialdehyde; Mice; Mice, Inbred BALB C; Neovascularization, Physiologic; Nitric Oxide Synthase; Oxidative Stress; Reactive Oxygen Species; Skin; Vascular Endothelial Growth Factors; Wound Healing; Wounds, Penetrating | 2010 |
[Effect of Ganoderma lucidum polysaccharides on hemodynamic and antioxidation in T2DM rats].
Topics: Animals; Antioxidants; Catalase; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Female; Glutathione; Hemodynamics; Hypoglycemic Agents; Male; Malondialdehyde; Microscopy, Electron, Transmission; Myocardium; Nitric Oxide; Polysaccharides; Rats; Rats, Sprague-Dawley; Reishi; Superoxide Dismutase | 2010 |
Protective effects of Pycnogenol on hyperglycemia-induced oxidative damage in the liver of type 2 diabetic rats.
Topics: Amino Acids; Animals; Antioxidants; Chromium; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Dietary Fats; Flavonoids; Glutathione; Glycated Hemoglobin; Hyperglycemia; Liver; Liver Glycogen; Male; Malondialdehyde; Nicotinic Acids; Oxidative Stress; Phytotherapy; Plant Extracts; Rats; Rats, Wistar; Thiobarbituric Acid Reactive Substances | 2010 |
2-hydroxy 4-methoxy benzoic acid isolated from roots of Hemidesmus indicus ameliorates liver, kidney and pancreas injury due to streptozotocin-induced diabetes in rats.
Topics: Animals; Benzoic Acid; Diabetes Mellitus, Experimental; Hemidesmus; Hypoglycemic Agents; Kidney; Liver; Male; Malondialdehyde; Medicine, Ayurvedic; Pancreas; Plant Roots; Plants, Medicinal; Rats; Rats, Wistar; Thiobarbituric Acid Reactive Substances; Tolbutamide | 2010 |
The effects of 17beta-estradiol and vitamin E treatments on oxidative stress and antioxidant levels in brain cortex of diabetic ovariectomized rats.
Topics: Animals; Antioxidants; beta Carotene; Blood Glucose; Catalase; Cerebral Cortex; Diabetes Mellitus, Experimental; Estradiol; Female; Glutathione; Glutathione Peroxidase; Lipid Peroxidation; Malondialdehyde; Ovariectomy; Oxidative Stress; Rats; Rats, Wistar; Superoxide Dismutase; Vitamin A; Vitamin E | 2010 |
Beneficial effects of oligopeptides from marine salmon skin in a rat model of type 2 diabetes.
Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Apoptosis; Blood Glucose; Diabetes Mellitus, Experimental; Dietary Fats; fas Receptor; Glutathione; Hyperglycemia; Hypoglycemic Agents; Interferon-gamma; Islets of Langerhans; Male; Malondialdehyde; Oligopeptides; Oxidative Stress; Protein Hydrolysates; Rats; Rats, Sprague-Dawley; Salmon; Serum Albumin; Streptozocin; Superoxide Dismutase; Tumor Necrosis Factor-alpha | 2010 |
The antioxidant effect of angiotensin II receptor blocker, losartan, in streptozotocin-induced diabetic rats.
Topics: Angiotensin II Type 1 Receptor Blockers; Animals; Antioxidants; Blood Glucose; Body Weight; Diabetes Mellitus, Experimental; Intercellular Adhesion Molecule-1; Losartan; Male; Malondialdehyde; Nitrates; Nitric Oxide; Pancreas; Rats; Rats, Wistar; Streptozocin; Vascular Endothelial Growth Factor A | 2010 |
Antidiabetic effects of total flavonoids from Litsea Coreana leve on fat-fed, streptozotocin-induced type 2 diabetic rats.
Topics: Animals; Antioxidants; Body Weight; C-Reactive Protein; Diabetes Mellitus, Experimental; Dietary Fats; Flavonoids; Hypoglycemic Agents; Insulin Resistance; Islets of Langerhans; Lipids; Litsea; Liver; Male; Malondialdehyde; Phytotherapy; Pioglitazone; Plant Extracts; Plant Leaves; Protein Tyrosine Phosphatase, Non-Receptor Type 1; Rats; Rats, Sprague-Dawley; Superoxide Dismutase; Thiazolidinediones | 2010 |
Tanshinone IIA improves impaired nerve functions in experimental diabetic rats.
Topics: Animals; Blood Glucose; Body Weight; Catalase; Diabetes Mellitus, Experimental; Diabetic Neuropathies; Drugs, Chinese Herbal; Hyperalgesia; Male; Malondialdehyde; Phenanthrenes; Rats; Rats, Sprague-Dawley; Sciatic Nerve; Sodium-Potassium-Exchanging ATPase; Superoxide Dismutase | 2010 |
Antidiabetic, antihyperlipidemic and antioxidant activities of methanolic extract of Amaranthus viridis Linn in alloxan induced diabetic rats.
Topics: Alloxan; alpha-Amylases; Amaranthus; Animals; Antioxidants; Blood Glucose; Catalase; Cholesterol; Diabetes Mellitus, Experimental; Glucose Tolerance Test; Glutathione; Glycerides; Hypoglycemic Agents; Hypolipidemic Agents; Lipid Peroxidation; Liver; Male; Malondialdehyde; Methanol; Plant Extracts; Rats; Sulfhydryl Compounds | 2012 |
Antioxidant enzymatic defense in salivary glands of streptozotocin-induced diabetic rats: a temporal study.
Topics: Animals; Antioxidants; Catalase; Diabetes Mellitus, Experimental; Glutathione Peroxidase; Lipid Peroxidation; Male; Malondialdehyde; Rats; Rats, Wistar; Salivary Glands; Superoxide Dismutase | 2010 |
Mechanistic study of endogenous skin lesions in diabetic rats.
Topics: Animals; Apoptosis; Cell Cycle; Cell Line; Cell Proliferation; Cell Survival; Cells, Cultured; Diabetes Complications; Diabetes Mellitus, Experimental; Endothelial Cells; Epidermis; Epithelial Cells; Glucose; Glutathione; Glycation End Products, Advanced; Male; Malondialdehyde; Microvessels; Oxidative Stress; Rats; Rats, Sprague-Dawley; Serum Albumin; Serum Albumin, Human; Skin; Skin Diseases | 2010 |
Effects of aspirin and nimesulide on tissue damage in diabetic rats.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Catalase; Diabetes Mellitus, Experimental; Glutathione Peroxidase; Lipid Peroxidation; Male; Malondialdehyde; Rats; Rats, Sprague-Dawley; Streptozocin; Sulfonamides; Superoxide Dismutase | 2010 |
p66Shc mediates high-glucose and angiotensin II-induced oxidative stress renal tubular injury via mitochondrial-dependent apoptotic pathway.
Topics: Angiotensin II; Animals; Apoptosis; Diabetes Mellitus, Experimental; DNA, Mitochondrial; Gene Expression Regulation; Glucose; In Situ Nick-End Labeling; Kidney Tubules; L-Lactate Dehydrogenase; Malondialdehyde; Mice; Mice, Inbred ICR; Microscopy, Confocal; Mitochondria; NIMA-Interacting Peptidylprolyl Isomerase; Oxidative Stress; Peptidylprolyl Isomerase; Protein Kinase C; Protein Kinase C beta; Reactive Oxygen Species; RNA, Small Interfering; Shc Signaling Adaptor Proteins; Signal Transduction; Src Homology 2 Domain-Containing, Transforming Protein 1 | 2010 |
Protective effect of berberine on antioxidant enzymes and positive transcription elongation factor b expression in diabetic rat liver.
Topics: Animals; Antioxidants; Berberine; Coptis; Cyclin T; Cyclin-Dependent Kinase 9; Diabetes Mellitus, Experimental; Diet; Drugs, Chinese Herbal; Enzymes; Fenofibrate; Hyperlipidemias; Hypoglycemic Agents; Hypolipidemic Agents; Lipid Peroxidation; Liver; Male; Malondialdehyde; Phytotherapy; Positive Transcriptional Elongation Factor B; Rats; Rats, Wistar; Rhizome; RNA, Messenger; Rosiglitazone; Thiazolidinediones; Up-Regulation | 2011 |
Oxidative stress is not associated with vascular dysfunction in a model of alloxan-induced diabetic rats.
Topics: Acetylcysteine; Alloxan; Animals; Aorta, Thoracic; Diabetes Mellitus, Experimental; Disease Models, Animal; Endothelium, Vascular; Free Radical Scavengers; Male; Malondialdehyde; Nitric Oxide; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Oxidative Stress; Random Allocation; Rats; Rats, Wistar; Time Factors | 2010 |
Effects of Nigella sativa and thymoquinone on biochemical and subcellular changes in pancreatic β-cells of streptozotocin-induced diabetic rats.
Topics: Animals; Benzoquinones; Blood Glucose; Diabetes Mellitus, Experimental; Insulin; Insulin-Secreting Cells; Male; Malondialdehyde; Oxidative Stress; Phytotherapy; Plant Extracts; Plant Oils; Rats; Rats, Sprague-Dawley; Superoxide Dismutase | 2010 |
Non-invasive limb ischemic pre-conditioning reduces oxidative stress and attenuates myocardium ischemia-reperfusion injury in diabetic rats.
Topics: Animals; Arrhythmias, Cardiac; Blood Pressure; Diabetes Mellitus, Experimental; Extremities; Gene Expression; Glutathione Peroxidase; Hemodynamics; Ischemic Preconditioning; Male; Malondialdehyde; Models, Animal; Myocardial Infarction; Myocardial Reperfusion Injury; Myocardium; Oxidative Stress; Rats; Rats, Wistar; Streptozocin; Superoxide Dismutase; Xanthine Oxidase | 2011 |
Antihyperglycemic activity of Selaginella tamariscina (Beauv.) Spring.
Topics: Animals; Blood Glucose; China; Diabetes Mellitus, Experimental; Drugs, Chinese Herbal; Ethanol; Ethnopharmacology; Hep G2 Cells; Humans; Hypoglycemic Agents; Insulin; Lipids; Liver Glycogen; Male; Malondialdehyde; Phytotherapy; Rats; Rats, Sprague-Dawley; Selaginellaceae; Superoxide Dismutase; Tumor Necrosis Factor-alpha; Water | 2011 |
Effect of lignin-derived lignophenols on vascular oxidative stress and inflammation in streptozotocin-induced diabetic rats.
Topics: 8-Hydroxy-2'-Deoxyguanosine; Animals; Anti-Inflammatory Agents; Antioxidants; Aorta; Blood Glucose; Body Weight; Chemokine CCL2; Deoxyguanosine; Diabetes Mellitus, Experimental; Fagus; Inflammation; Lignin; Lipids; Male; Malondialdehyde; NADPH Oxidase 4; NADPH Oxidases; Nitric Oxide Synthase Type II; Oxidative Stress; Phenols; Rats; Rats, Wistar; Receptors, CCR2; RNA, Messenger; Superoxides; Time Factors | 2011 |
U83836E inhibits retinal neurodegeneration in early-stage streptozotocin-induced diabetic rats.
Topics: Animals; Antioxidants; Blood Glucose; Chromans; Chromatography, High Pressure Liquid; Diabetes Mellitus, Experimental; Diabetic Retinopathy; Electroretinography; Lipid Peroxidation; Male; Malondialdehyde; Neuroglia; Neuroprotective Agents; Piperazines; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Retinal Degeneration; Retinal Ganglion Cells; Superoxide Dismutase | 2011 |
Anti-hyperglycemic, antioxidant and anti-inflammatory effects of VIP and a VPAC1 agonist on streptozotocin-induced diabetic mice.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Antioxidants; Blood Glucose; Body Weight; C-Reactive Protein; Diabetes Mellitus, Experimental; Eating; Glucose Tolerance Test; Hydrogen Peroxide; Hypoglycemic Agents; Insulin; Interleukin-10; Liver; Male; Malondialdehyde; Mice; Mice, Inbred Strains; NF-kappa B; Pancreas; Peptide Fragments; Receptors, Vasoactive Intestinal Polypeptide, Type I; Spleen; Tumor Necrosis Factor-alpha; Vasoactive Intestinal Peptide | 2011 |
Modulation of oxidative stress by Chlorella vulgaris in streptozotocin (STZ) induced diabetic Sprague-Dawley rats.
Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Catalase; Chlorella vulgaris; Diabetes Mellitus, Experimental; Lipid Peroxidation; Male; Malondialdehyde; Oxidative Stress; Rats; Rats, Sprague-Dawley; Superoxide Dismutase | 2010 |
Antihyperglycemic activity of bacosine, a triterpene from Bacopa monnieri, in alloxan-induced diabetic rats.
Topics: alpha-Tocopherol; Animals; Antioxidants; Bacopa; Blood Glucose; Catalase; Diabetes Mellitus, Experimental; Female; Glutathione; Glutathione Peroxidase; Glyburide; Glycated Hemoglobin; Hypoglycemic Agents; Insulin; Liver; Liver Glycogen; Male; Malondialdehyde; Oxidative Stress; Plant Extracts; Rats; Rats, Wistar; Superoxide Dismutase; Triterpenes | 2011 |
[The protective function of puerarin to the injury of the lung and its mechanisms during diabetes].
Topics: Animals; Blood Glucose; Diabetes Mellitus, Experimental; Isoflavones; Lung; Lung Injury; Malondialdehyde; Nitric Oxide; Oxidative Stress; Rats; Rats, Sprague-Dawley; Superoxide Dismutase | 2007 |
Testicular oxidative damage and role of combined antioxidant supplementation in experimental diabetic rats.
Topics: Animals; Antioxidants; Apoptosis; Ascorbic Acid; Caspase 3; Diabetes Mellitus, Experimental; Dietary Supplements; Glutathione Peroxidase; Male; Malondialdehyde; Rats; Superoxide Dismutase; Testis; Thioctic Acid; Vitamin E | 2011 |
Satureja khozestanica essential oil ameliorates progression of diabetic nephropathy in uninephrectomized diabetic rats.
Topics: Animals; Creatinine; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Disease Progression; Gas Chromatography-Mass Spectrometry; Kidney Glomerulus; Malondialdehyde; Nephrectomy; Oils, Volatile; Organ Size; Phytotherapy; Rats; Satureja; Urea | 2011 |
Ameliorative effects of glycyrrhizin on streptozotocin-induced diabetes in rats.
Topics: Animals; Blood Glucose; Catalase; Cholesterol; Diabetes Mellitus, Experimental; Free Radicals; Fructosamine; Glucose Intolerance; Glyburide; Glycated Hemoglobin; Glycyrrhizic Acid; Hemoglobins; Hyperglycemia; Hyperlipidemias; Insulin; Islets of Langerhans; Kidney; Male; Malondialdehyde; Oxidative Stress; Pancreas; Rats; Rats, Wistar; Superoxide Dismutase | 2011 |
Alterations of antioxidant biomarkers and type I collagen deposition in the parotid gland of streptozotocin-induced diabetic rats.
Topics: Acarbose; Alanine Transaminase; Alkaline Phosphatase; Animals; Antioxidants; Aspartate Aminotransferases; Biomarkers; Blood Glucose; Blood Proteins; Cholesterol; Collagen Type I; Creatinine; Diabetes Mellitus, Experimental; Free Radical Scavengers; gamma-Glutamyltransferase; Glutathione Peroxidase; Hypoglycemic Agents; Male; Malondialdehyde; Oxidative Stress; Parotid Gland; Rats; Rats, Wistar; Streptozocin; Superoxide Dismutase; Triglycerides; Urea | 2011 |
[Effects of taurine on hemorheology of rats with type 2 diabetes].
Topics: Animals; Blood Glucose; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Erythrocyte Deformability; Glycated Hemoglobin; Hemorheology; Male; Malondialdehyde; Oxidative Stress; Rats; Rats, Wistar; Superoxide Dismutase; Taurine | 2010 |
[Protective effect of extract of Apocynum venetum on kidneys of streptozotocin-induced diabetic rats].
Topics: Animals; Apocynum; Blood Glucose; Blood Urea Nitrogen; Creatinine; Diabetes Mellitus, Experimental; Drugs, Chinese Herbal; Fructosamine; Glutathione Peroxidase; Kidney; Kidney Cortex; Male; Malondialdehyde; Oxidative Stress; Rats; Rats, Wistar; Superoxide Dismutase | 2010 |
Effect of streptozocin-induced diabetes mellitus on expression of methionine sulfoxide reductases and accumulation of their substrates in mouse lenses.
Topics: Animals; Blotting, Western; Diabetes Mellitus, Experimental; Electrophoresis, Polyacrylamide Gel; Gene Expression Regulation, Enzymologic; Lens, Crystalline; Male; Malondialdehyde; Methionine Sulfoxide Reductases; Mice; Microfilament Proteins; Oxidative Stress; Oxidoreductases; Protein Carbonylation; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Streptozocin | 2011 |
[Effects of tert-butylhydroquinone on oxidative stress in kidneys of diabetic mice].
Topics: Animals; Diabetes Mellitus, Experimental; Hydroquinones; Kidney; Male; Malondialdehyde; Mice; Oxidative Stress; Superoxide Dismutase | 2011 |
Ulva rigida improves carbohydrate metabolism, hyperlipidemia and oxidative stress in streptozotocin-induced diabetic rats.
Topics: Animals; Blood Glucose; Carbohydrate Metabolism; Diabetes Mellitus, Experimental; Disease Models, Animal; Humans; Hyperlipidemias; Male; Malondialdehyde; Oxidative Stress; Plant Preparations; Random Allocation; Rats; Rats, Wistar; Ulva | 2011 |
Attenuation of glomerular injury in diabetic mice with tert-butylhydroquinone through nuclear factor erythroid 2-related factor 2-dependent antioxidant gene activation.
Topics: Animals; Antioxidants; Blood Glucose; Cell Nucleus; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Gene Expression Regulation; Glutamate-Cysteine Ligase; Heme Oxygenase-1; Hydroquinones; Hyperglycemia; Kidney Glomerulus; Male; Malondialdehyde; Mice; Microscopy, Electron, Transmission; NF-E2-Related Factor 2; Transcriptional Activation | 2011 |
Protective effects of an aqueous extract from pepino (Solanum muricatum Ait.) in diabetic mice.
Topics: Aldehyde Reductase; Animals; Antioxidants; Ascorbic Acid; Blood Glucose; Catalase; Chemokine CCL2; Diabetes Mellitus, Experimental; Fruit; Glutathione; Glutathione Peroxidase; Hypoglycemic Agents; Insulin; Kidney; Male; Malondialdehyde; Mice; Mice, Inbred BALB C; Phytotherapy; Plant Extracts; Polyphenols; Reactive Oxygen Species; Solanum; Sorbitol | 2011 |
Contribution of endogenous inhibitor of nitric oxide synthase to hepatic mitochondrial dysfunction in streptozotocin-induced diabetic rats.
Topics: Adenosine Triphosphate; Animals; Arginine; Cell Line, Tumor; Diabetes Mellitus, Experimental; Enzyme Inhibitors; Hepatocytes; Ion Channels; Liver; Male; Malondialdehyde; Membrane Potential, Mitochondrial; Mitochondria, Liver; Mitochondrial Proteins; Nitric Oxide; Nitric Oxide Synthase; Oxidative Stress; Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha; Rats; Rats, Sprague-Dawley; RNA-Binding Proteins; Superoxide Dismutase; Transcription Factors; Uncoupling Protein 2 | 2011 |
Edaravone ameliorates diabetes-induced dysfunction of NO-induced relaxation in corpus cavernosum smooth muscle in the rat.
Topics: Animals; Antipyrine; Blood Glucose; Cyclic GMP; Diabetes Mellitus, Experimental; Edaravone; Free Radical Scavengers; Impotence, Vasculogenic; Male; Malondialdehyde; Muscle, Smooth, Vascular; Nitric Oxide; Penis; Rats; Rats, Wistar; Reactive Oxygen Species; Vasodilation | 2011 |
17β-Estradiol and vitamin E modulates oxidative stress-induced kidney toxicity in diabetic ovariectomized rat.
Topics: Animals; Antioxidants; Blood Proteins; Blood Urea Nitrogen; Creatinine; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Estradiol; Female; Kidney; Lipid Peroxidation; Malondialdehyde; Ovariectomy; Oxidative Stress; Rats; Rats, Wistar; Serum Albumin; Vitamin E; Vitamins | 2011 |
[Mechanisms of oxidative stress-induced damage and its protection in cavernous mitochondria of diabetic rats].
Topics: Animals; Diabetes Mellitus, Experimental; Erectile Dysfunction; Glutathione; Male; Malondialdehyde; Mitochondria; Oxidative Stress; Penis; Random Allocation; Rats; Rats, Sprague-Dawley; Superoxide Dismutase | 2011 |
Effects of salvianolic scid A on plantar microcirculation and peripheral nerve function in diabetic rats.
Topics: Animals; Aorta; Blood Glucose; Body Weight; Caffeic Acids; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Diabetic Foot; Foot; Glycation End Products, Advanced; Hyperemia; Lactates; Lipid Metabolism; Male; Malondialdehyde; Microcirculation; Motor Activity; Nitric Oxide Synthase Type III; Pain; Peripheral Nerves; Rats; Rats, Sprague-Dawley; Reaction Time; Survival Rate; von Willebrand Factor | 2011 |
Lycopene attenuates endothelial dysfunction in streptozotocin-induced diabetic rats by reducing oxidative stress.
Topics: Administration, Oral; Animals; Antioxidants; Aorta, Thoracic; Blood Glucose; Carotenoids; Diabetes Mellitus, Experimental; Diabetic Angiopathies; Dose-Response Relationship, Drug; Endothelium, Vascular; Lipids; Lycopene; Male; Malondialdehyde; Nitric Oxide; Nitric Oxide Synthase Type II; Oxidative Stress; Rats; Rats, Wistar; Superoxide Dismutase; Vasodilation | 2011 |
SOD1 overexpression in vivo blocks hyperglycemia-induced specific PKC isoforms: substrate activation and consequent lipid peroxidation in diabetic embryopathy.
Topics: Aldehydes; Animals; Diabetes Complications; Diabetes Mellitus, Experimental; Female; Fetal Diseases; Hyperglycemia; Intracellular Signaling Peptides and Proteins; Isoenzymes; Lipid Peroxidation; Male; Malondialdehyde; Membrane Proteins; Mice; Mice, Inbred C57BL; Mice, Transgenic; Myristoylated Alanine-Rich C Kinase Substrate; Neuropeptides; Pregnancy; Protein Kinase C; Protein Kinase C beta; Protein Kinase C-alpha; Protein Kinase C-delta; Receptors for Activated C Kinase; Superoxide Dismutase; Superoxide Dismutase-1 | 2011 |
Effect of selenium on connexin expression, angiogenesis, and antioxidant status in diabetic wound healing.
Topics: Animals; Antioxidants; Blood Glucose; Connexins; Diabetes Mellitus, Experimental; DNA, Complementary; Lipid Peroxidation; Male; Malondialdehyde; Mice; Neovascularization, Physiologic; Polymerase Chain Reaction; RNA; Selenium; Superoxide Dismutase; Vascular Endothelial Growth Factor A; Wound Healing | 2011 |
Regulation of cardiac oxidative stress and lipid peroxidation in streptozotocin-induced diabetic rats treated with aqueous extract of Pimpinella tirupatiensis tuberous root.
Topics: Animals; Antioxidants; Blood Glucose; Diabetes Mellitus, Experimental; Glyburide; Hypoglycemic Agents; Lipid Peroxidation; Male; Malondialdehyde; Myocardium; Oxidative Stress; Pimpinella; Plant Extracts; Plant Roots; Rats; Rats, Wistar; Streptozocin; Water | 2013 |
Ameliorative effect of astaxanthin on endothelial dysfunction in streptozotocin-induced diabetes in male rats.
Topics: Animals; Biomarkers; Blotting, Western; Body Weight; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Endothelium; Fibrinolytic Agents; Fluorescent Antibody Technique; Isometric Contraction; Lipid Peroxidation; Lipids; Male; Malondialdehyde; Muscle, Smooth, Vascular; Oxidative Stress; Rats; Rats, Wistar; Reverse Transcriptase Polymerase Chain Reaction; Vasodilation; Xanthophylls | 2011 |
The effect of supplementation of grape seed proanthocyanidin extract on vascular dysfunction in experimental diabetes.
Topics: Acetylcholine; Animals; Antioxidants; Aorta, Thoracic; Diabetes Mellitus, Experimental; Dietary Supplements; Endothelium, Vascular; Grape Seed Extract; In Vitro Techniques; Lipid Peroxidation; Male; Malondialdehyde; Nitroprusside; Oxidative Stress; Proanthocyanidins; Rats; Rats, Sprague-Dawley; Superoxide Dismutase | 2011 |
Effects of the Chinese Yi-Qi-Bu-Shen Recipe extract on brainstem auditory evoked potential in rats with diabetes.
Topics: Acoustic Stimulation; Animals; Biogenic Monoamines; Blood Glucose; Body Weight; Brain Stem; Diabetes Mellitus, Experimental; Drugs, Chinese Herbal; Evoked Potentials, Auditory, Brain Stem; Hypoglycemic Agents; Insulin; Insulin Resistance; Male; Malondialdehyde; Neural Conduction; Neuroprotective Agents; Rats; Rats, Wistar; Superoxide Dismutase | 2011 |
Antihyperglycemic and neuroprotective effects of one novel Cu-Zn SOD mimetic.
Topics: Animals; Biomimetic Materials; Coordination Complexes; Diabetes Mellitus, Experimental; Hypoglycemic Agents; Malondialdehyde; Mice; Neuroprotective Agents; Oxidative Stress; Superoxide Dismutase | 2011 |
Protective effect of taurine on diabetic rat endothelial dysfunction.
Topics: Acetylcholine; Animals; Blood Glucose; Body Weight; Diabetes Mellitus, Experimental; Endothelium, Vascular; In Vitro Techniques; Male; Malondialdehyde; Nitric Oxide Synthase Type III; Norepinephrine; Oxidative Stress; Rats; Rats, Wistar; Receptor, Muscarinic M3; RNA, Messenger; Taurine; Up-Regulation; Vasodilation | 2011 |
Differential responses to blood pressure and oxidative stress in streptozotocin-induced diabetic Wistar-Kyoto rats and spontaneously hypertensive rats: effects of antioxidant (honey) treatment.
Topics: Administration, Oral; Animals; Antioxidants; Blood Glucose; Blood Pressure; Body Weight; Diabetes Mellitus, Experimental; Glutathione; Honey; Hypertension; Kidney; Male; Malondialdehyde; Oxidative Stress; Oxidoreductases; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Streptozocin | 2011 |
Chronic epigallocatechin-3-gallate ameliorates learning and memory deficits in diabetic rats via modulation of nitric oxide and oxidative stress.
Topics: Animals; Avoidance Learning; Blood Glucose; Body Weight; Catechin; Diabetes Mellitus, Experimental; Hippocampus; Indazoles; Learning Disabilities; Male; Malondialdehyde; Maze Learning; Memory Disorders; Nerve Tissue Proteins; Neuroprotective Agents; Nitric Oxide; Nitric Oxide Donors; Nitric Oxide Synthase Type I; Nitrites; Oxidative Stress; Rats; Rats, Wistar | 2011 |
Anti-diabetic activity and potential mechanism of total flavonoids of Selaginella tamariscina (Beauv.) Spring in rats induced by high fat diet and low dose STZ.
Topics: Adipose Tissue; Animals; Biomarkers; Blood Glucose; Diabetes Mellitus, Experimental; Dietary Fats; Dose-Response Relationship, Drug; Flavonoids; Glucagon; Glucose Tolerance Test; Glycated Hemoglobin; Hypoglycemic Agents; Insulin; Insulin Receptor Substrate Proteins; Lipids; Liver; Male; Malondialdehyde; Muscle, Skeletal; Plant Extracts; Plants, Medicinal; PPAR gamma; Rats; Rats, Wistar; Selaginellaceae; Streptozocin; Superoxide Dismutase; Time Factors | 2011 |
α-Linolenic acid intake attenuates myocardial ischemia/reperfusion injury through anti-inflammatory and anti-oxidative stress effects in diabetic but not normal rats.
Topics: alpha-Linolenic Acid; Animals; Anti-Inflammatory Agents; Antioxidants; Blood Glucose; Body Weight; Creatine Kinase; Diabetes Mellitus, Experimental; Dietary Fats; Dietary Supplements; Heart; Insulin; L-Lactate Dehydrogenase; Male; Malondialdehyde; Membrane Glycoproteins; Myocardial Reperfusion Injury; Myocardium; NADPH Oxidase 2; NADPH Oxidases; Necrosis; Oxidative Stress; Phosphatidylinositol 3-Kinases; Phosphorylation; Proto-Oncogene Proteins c-akt; Rats; Rats, Sprague-Dawley; Recovery of Function; Superoxide Dismutase; Superoxides; Triglycerides | 2011 |
Changes in prooxidant-antioxidant balance in tissues of rats following long-term hyperglycemic status.
Topics: Animals; Antioxidants; Ascorbic Acid; Diabetes Mellitus, Experimental; Hyperglycemia; Iron; Liver; Male; Malondialdehyde; Oxidative Stress; Rats; Rats, Wistar; Reactive Oxygen Species; Superoxide Dismutase | 2011 |
Evaluation of antidiabetic potential of selected traditional Chinese medicines in STZ-induced diabetic mice.
Topics: Administration, Oral; Aldehyde Reductase; alpha-Glucosidases; Angiotensin-Converting Enzyme Inhibitors; Animals; Antioxidants; Blood Glucose; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Drugs, Chinese Herbal; Female; Glycoside Hydrolase Inhibitors; Hypertrophy; Hypoglycemic Agents; Kidney; Male; Malondialdehyde; Mice; Peptidyl-Dipeptidase A; Plants, Medicinal; Superoxide Dismutase; Time Factors | 2011 |
Trigonella foenum graecum seed extract protects kidney function and morphology in diabetic rats via its antioxidant activity.
Topics: 8-Hydroxy-2'-Deoxyguanosine; Animals; Antioxidants; Biomarkers; Blood Glucose; Blood Urea Nitrogen; Body Weight; Catalase; Creatinine; Deoxyguanosine; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Diet; DNA; Dose-Response Relationship, Drug; Hypoglycemic Agents; Insulin Resistance; Kidney; Male; Malondialdehyde; Organ Size; Oxidative Stress; Phytotherapy; Plant Extracts; Rats; Rats, Sprague-Dawley; Seeds; Superoxide Dismutase; Trigonella | 2011 |
Effect of aqueous extract of the leaves of Acalypha wilkesiana 'Godseffiana' Muell Arg (Euphorbiaceae) on the hematology, plasma biochemistry and ocular indices of oxidative stress in alloxan induced diabetic rats.
Topics: Animals; Antioxidants; Aspartate Aminotransferases; Bilirubin; Biomarkers; Blood Cell Count; Blood Cells; Blood Glucose; Blood Urea Nitrogen; Calcium; Cholesterol, HDL; Cholesterol, VLDL; Chromatography, Gas; Diabetes Mellitus, Experimental; Dose-Response Relationship, Drug; Euphorbiaceae; Eye; Hypoglycemic Agents; Kidney; Liver; Malondialdehyde; Metformin; Oxidative Stress; Plant Extracts; Plant Leaves; Plants, Medicinal; Rats; Rats, Wistar; Solvents; Triglycerides; Urea | 2011 |
Intramuscular injection of soluble receptor for advanced glycation endproducts expression vector prevents the development of streptozotocin-induced diabetes mellitus in rats on high fat diet.
Topics: Animals; Blood Glucose; Diabetes Mellitus, Experimental; Diet, High-Fat; Disease Models, Animal; Genetic Vectors; Glycation End Products, Advanced; Injections, Intramuscular; Male; Malondialdehyde; Rats; Rats, Sprague-Dawley; Streptozocin | 2011 |
Ellagic acid attenuates oxidative stress on brain and sciatic nerve and improves histopathology of brain in streptozotocin-induced diabetic rats.
Topics: Animals; Aryldialkylphosphatase; Brain; Catalase; Diabetes Mellitus, Experimental; Disease Models, Animal; Ellagic Acid; Female; Malondialdehyde; Neuroprotective Agents; Nitric Oxide; Oxidative Stress; Rats; Rats, Wistar; Sciatic Nerve; Statistics, Nonparametric | 2012 |
The hypoglycemic activity of Lithocarpus polystachyus Rehd. leaves in the experimental hyperglycemic rats.
Topics: Animals; Blood Glucose; Blood Proteins; C-Reactive Protein; Cholesterol; Creatinine; Diabetes Mellitus, Experimental; Fagaceae; Flavonoids; Glycated Serum Proteins; Glycoproteins; Hyperglycemia; Hypoglycemic Agents; Insulin; Insulin Resistance; Liver; Male; Malondialdehyde; Nitrogen; Phytotherapy; Plant Extracts; Plant Leaves; Rats; Rats, Sprague-Dawley; Superoxide Dismutase; Triglycerides; Urea | 2011 |
Effect of Morus nigra aqueous extract treatment on the maternal-fetal outcome, oxidative stress status and lipid profile of streptozotocin-induced diabetic rats.
Topics: Animals; Antioxidants; Blood Glucose; Bone and Bones; Brazil; Diabetes Mellitus, Experimental; Female; Fetal Development; Hypoglycemic Agents; Lipids; Male; Malondialdehyde; Maternal-Fetal Exchange; Medicine, Traditional; Morus; Oxidative Stress; Plant Extracts; Plant Leaves; Pregnancy; Pregnancy in Diabetics; Rats; Rats, Wistar; Superoxide Dismutase | 2011 |
Insulin resistance mediated biochemical alterations in eye lens of neonatal streptozotocin-induced diabetic rat.
Topics: Animals; Animals, Newborn; Antioxidants; Blood Glucose; Cataract; Crystallins; Diabetes Mellitus, Experimental; Fasting; Glucose Tolerance Test; Insulin Resistance; Lens, Crystalline; Male; Malondialdehyde; Oxidative Stress; Rats; Rats, Wistar; Streptozocin | 2011 |
Protective effect of Icariin on the early stage of experimental diabetic nephropathy induced by streptozotocin via modulating transforming growth factor β1 and type IV collagen expression in rats.
Topics: Animals; Blood Glucose; Blood Urea Nitrogen; Collagen Type IV; Creatinine; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Drugs, Chinese Herbal; Flavonoids; Hydroxyproline; Kidney; Male; Malondialdehyde; Protective Agents; Rats; Rats, Sprague-Dawley; Streptozocin; Superoxide Dismutase; Transforming Growth Factor beta1 | 2011 |
Modulation of AT-1R/CHOP-JNK-Caspase12 pathway by olmesartan treatment attenuates ER stress-induced renal apoptosis in streptozotocin-induced diabetic mice.
Topics: Angiotensin II Type 1 Receptor Blockers; Animals; Apoptosis; Blood Glucose; Caspase 12; Diabetes Mellitus, Experimental; Endoplasmic Reticulum; Endoplasmic Reticulum Chaperone BiP; Heat-Shock Proteins; Imidazoles; JNK Mitogen-Activated Protein Kinases; Kidney; Lipid Peroxidation; Malondialdehyde; Membrane Proteins; Mice; Olmesartan Medoxomil; Protein Serine-Threonine Kinases; Receptor, Angiotensin, Type 1; Superoxides; Tetrazoles; TNF Receptor-Associated Factor 2; Transcription Factor CHOP | 2011 |
Oral administration of ethyl acetate-soluble portion of Terminalia chebula conferring protection from streptozotocin-induced diabetic mellitus and its complications.
Topics: Administration, Oral; Animals; Aorta, Thoracic; Blood Glucose; Diabetes Mellitus, Experimental; Fruit; Glycation End Products, Advanced; Hypoglycemic Agents; Kidney; Kidney Diseases; Lipids; Liver; Liver Diseases; Male; Malondialdehyde; Phytotherapy; Plant Extracts; Rats; Rats, Sprague-Dawley; Seminiferous Tubules; Solubility; Terminalia | 2011 |
Chromium, selenium, and zinc multimineral enriched yeast supplementation ameliorates diabetes symptom in streptozocin-induced mice.
Topics: Animals; Blood Glucose; Chromium; Diabetes Mellitus, Experimental; Dietary Supplements; Glutathione; Glutathione Peroxidase; Interleukin-2; Interleukin-4; Islets of Langerhans; Kidney; Lipids; Liver; Male; Malondialdehyde; Mice; Mice, Inbred BALB C; Random Allocation; Selenium; Spleen; Streptozocin; Superoxide Dismutase; Thymus Gland; Yeast, Dried; Zinc | 2012 |
Alpha-lipoic acid preserves the structural and functional integrity of red blood cells by adjusting the redox disturbance and decreasing O-GlcNAc modifications of antioxidant enzymes and heat shock proteins in diabetic rats.
Topics: Acetylglucosamine; Animals; Antioxidants; Catalase; Diabetes Mellitus, Experimental; Electrophoresis, Polyacrylamide Gel; Erythrocytes; Glutathione; HSP70 Heat-Shock Proteins; HSP90 Heat-Shock Proteins; Iron; Lipid Peroxidation; Male; Malondialdehyde; Oxidation-Reduction; Oxidative Stress; Rats; Rats, Wistar; Streptozocin; Superoxide Dismutase; Thioctic Acid | 2012 |
Hypoglycemic and hypolipidemic effects of polyphenols from burs of Castanea mollissima Blume.
Topics: Animals; Blood Glucose; Body Weight; Diabetes Mellitus, Experimental; Fagaceae; Fruit; Glutathione; Hypoglycemic Agents; Hypolipidemic Agents; Lipids; Male; Malondialdehyde; Plant Components, Aerial; Plant Extracts; Polyphenols; Rats; Rats, Wistar; Streptozocin | 2011 |
Protective effect of herbomineral formulation (Dolabi) on early diabetic nephropathy in streptozotocin-induced diabetic rats.
Topics: Animals; Antioxidants; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Hypoglycemic Agents; Kidney; Lipid Peroxidation; Malondialdehyde; Rats; Superoxide Dismutase | 2012 |
The protective effect of losartan in the nephropathy of the diabetic rat includes the control of monoamine oxidase type A activity.
Topics: Aldehyde Dehydrogenase; Angiotensin II Type 1 Receptor Blockers; Animals; Catalase; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Losartan; Malondialdehyde; Monoamine Oxidase; Oxidative Stress; Protective Agents; Protein Carbonylation; Rats; Rats, Wistar; Superoxide Dismutase | 2012 |
Protective effect of salidroside from Rhodiolae Radix on diabetes-induced oxidative stress in mice.
Topics: Animals; Antioxidants; Blood Glucose; Body Weight; Diabetes Mellitus, Experimental; Fasting; Glucosides; Insulin; Kidney; Lipids; Liver; Male; Malondialdehyde; Mice; Oxidative Stress; Phenols; Protective Agents; Rhodiola | 2011 |
Effects of combined leaf extract of Vernonia amygdalina and Azadirachta indica on hepatic morphology and hepatotoxicity markers in streptozotocin-induced diabetic rats.
Topics: Animals; Azadirachta; Diabetes Mellitus, Experimental; Drug Therapy, Combination; Glutathione Peroxidase; Liver; Male; Malondialdehyde; Oxidative Stress; Phytotherapy; Plant Extracts; Plant Leaves; Random Allocation; Rats; Rats, Wistar; Vernonia | 2011 |
Abrogation of maternal and fetal oxidative stress in the streptozotocin-induced diabetic rat by dietary supplements of Tinospora cordifolia.
Topics: Animals; Antioxidants; Blood Glucose; Diabetes Mellitus, Experimental; Diet; Dietary Supplements; Female; Fetal Diseases; Glutathione; Glutathione Peroxidase; Male; Malondialdehyde; Oxidative Stress; Plant Extracts; Pregnancy; Pregnancy Complications; Rats; Rats, Wistar; Reactive Oxygen Species; Superoxide Dismutase; Tinospora | 2012 |
Ginsenoside Re attenuates diabetes-associated cognitive deficits in rats.
Topics: Animals; Antioxidants; Blood Glucose; Body Weight; Brain Chemistry; Cognition Disorders; Diabetes Mellitus, Experimental; Ginsenosides; Glutathione; Inflammation; Lipid Peroxidation; Male; Malondialdehyde; Maze Learning; Memory; Rats; Rats, Sprague-Dawley; Tumor Necrosis Factor-alpha | 2012 |
Comparison of sildenafil with strontium fructose diphosphate in improving erectile dysfunction against upregulated cavernosal NADPH oxidase, protein kinase Cε, and endothelin system in diabetic rats.
Topics: Animals; Blood Glucose; Blotting, Western; Diabetes Mellitus, Experimental; Disease Models, Animal; Endothelin-1; Erectile Dysfunction; Fructosediphosphates; Male; Malondialdehyde; NADPH Oxidases; Piperazines; Protein Kinase C-epsilon; Purines; Rats; Rats, Sprague-Dawley; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Sildenafil Citrate; Sulfones; Superoxide Dismutase; Up-Regulation; Vasodilator Agents | 2012 |
Chronic cyanidin-3-glucoside administration improves short-term spatial recognition memory but not passive avoidance learning and memory in streptozotocin-diabetic rats.
Topics: Animals; Anthocyanins; Avoidance Learning; Behavior, Animal; Brain; Diabetes Mellitus, Experimental; Drug Evaluation, Preclinical; Glucosides; Male; Malondialdehyde; Maze Learning; Memory, Short-Term; Mental Recall; Oxidative Stress; Rats; Rats, Wistar; Recognition, Psychology; Spatial Behavior; Streptozocin | 2012 |
Aldehyde and xanthine oxidase activities in tissues of streptozotocin-induced diabetic rats: effects of vitamin E and selenium supplementation.
Topics: Aldehyde Oxidase; Animals; Antioxidants; Aryldialkylphosphatase; Blood Glucose; Diabetes Mellitus, Experimental; Dietary Supplements; Erythrocytes; Female; Glutathione Peroxidase; Kidney; Lipids; Liver; Malondialdehyde; Rats; Rats, Sprague-Dawley; Sodium Selenite; Streptozocin; Superoxide Dismutase; Vitamin E; Vitamins; Xanthine Oxidase | 2012 |
Fenugreek attenuation of diabetic nephropathy in alloxan-diabetic rats: attenuation of diabetic nephropathy in rats.
Topics: Alloxan; Animals; Anti-Inflammatory Agents; Antioxidants; Catalase; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Glutathione; Interleukin-6; Kidney; Lipid Peroxidation; Malondialdehyde; Metformin; Oxidative Stress; Phytotherapy; Plant Extracts; Rats; Rosiglitazone; Superoxide Dismutase; Thiazolidinediones; Trigonella | 2012 |
Oxidative damage is ameliorated by curcumin treatment in brain and sciatic nerve of diabetic rats.
Topics: Animals; Brain; Chromans; Curcumin; Diabetes Mellitus, Experimental; Disease Models, Animal; Female; Hydrogen Peroxide; Lipid Peroxidation; Malondialdehyde; Nitric Oxide; Oxidation-Reduction; Oxidative Stress; Rats; Rats, Wistar; Sciatic Nerve | 2012 |
Antioxidant and anti-inflammatory effects of a hypoglycemic fraction from Cucurbita ficifolia Bouché in streptozotocin-induced diabetes mice.
Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Blood Glucose; Cucurbita; Cytokines; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Fruit; Glutathione; Hypoglycemic Agents; Inflammation Mediators; Inositol; Liver; Male; Malondialdehyde; Mice; Mice, Inbred Strains; Oxidative Stress; Phytotherapy; Pioglitazone; Plant Extracts; Thiazolidinediones | 2012 |
Anti-diabetic and anti-oxidant effects of Zingiber officinale on alloxan-induced and insulin-resistant diabetic male rats.
Topics: Administration, Oral; Alloxan; Animals; Antioxidants; Blood Glucose; Diabetes Mellitus, Experimental; Hypoglycemic Agents; Insulin; Insulin Resistance; Male; Malondialdehyde; Plant Extracts; Plants, Medicinal; Rats; Time Factors; Zingiber officinale | 2011 |
Saponin rich fractions from Polygonatum odoratum (Mill.) Druce with more potential hypoglycemic effects.
Topics: 1-Butanol; Alkanes; Animals; Blood Glucose; Chemical Fractionation; Diabetes Mellitus, Experimental; Dose-Response Relationship, Drug; Ethanol; Flavonoids; Glycoside Hydrolases; Hep G2 Cells; Humans; Hypoglycemic Agents; Liver; Male; Malondialdehyde; Phytotherapy; Plants, Medicinal; Polygonatum; Rats; Rats, Sprague-Dawley; Rhizome; Saponins; Solvents; Superoxide Dismutase; Time Factors; Water | 2012 |
Mobilisation of endothelial progenitor cells: one of the possible mechanisms involved in the chronic administration of melatonin preventing erectile dysfunction in diabetic rats.
Topics: Animals; Antioxidants; Diabetes Complications; Diabetes Mellitus, Experimental; Endothelium, Vascular; Erectile Dysfunction; Hematopoietic Stem Cell Mobilization; Male; Malondialdehyde; Melatonin; Oxidative Stress; Penis; Rats; Stem Cells; Superoxide Dismutase | 2012 |
Complete failure of insulin-transmitted signaling, but not obesity-induced insulin resistance, impairs respiratory chain function in muscle.
Topics: Animals; Autophagy; Blood Glucose; Carnitine O-Palmitoyltransferase; Diabetes Mellitus, Experimental; Diet, High-Fat; Electron Transport; Electron Transport Chain Complex Proteins; Gene Expression; Glucosylceramides; Insulin; Insulin Resistance; Lipid Metabolism; Male; Malondialdehyde; Mice; Mice, Inbred C57BL; Mice, Knockout; Mice, Obese; Mitochondria, Muscle; Mitochondrial Proteins; Muscle, Skeletal; Obesity; Oxidative Stress; Oxygen Consumption; Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha; Signal Transduction; Streptozocin; Trans-Activators; Transcription Factors | 2012 |
Long-term administration of fasudil improves cardiomyopathy in streptozotocin-induced diabetic rats.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Angiotensin-Converting Enzyme Inhibitors; Animals; Antioxidants; Apoptosis; Blood Glucose; Body Weight; Captopril; Diabetes Mellitus, Experimental; Diabetic Cardiomyopathies; Enzyme Inhibitors; Hemodynamics; In Situ Nick-End Labeling; Male; Malondialdehyde; Microscopy, Electron, Transmission; Myocardium; Organ Size; Rats; Rats, Wistar; Real-Time Polymerase Chain Reaction; rho-Associated Kinases; Superoxide Dismutase | 2012 |
Silymarin regulates the cytochrome P450 3A2 and glutathione peroxides in the liver of streptozotocin-induced diabetic rats.
Topics: Animals; Antioxidants; Blood Glucose; Cytochrome P-450 CYP3A; Diabetes Mellitus, Experimental; Drug Therapy, Combination; Glutathione Peroxidase; Glycogen; Liver; Male; Malondialdehyde; Melatonin; Necrosis; Nitric Oxide; Phytotherapy; Plant Extracts; Rats; Rats, Wistar; RNA, Messenger; Silybum marianum; Silymarin; Sulfhydryl Compounds; Urination; Weight Loss | 2012 |
Renal protective effect of Rosa laevigata Michx. by the inhibition of oxidative stress in streptozotocin-induced diabetic rats.
Topics: Animals; Chemokine CCL2; Diabetes Mellitus, Experimental; Diabetic Nephropathies; I-kappa B Proteins; Kidney; Male; Malondialdehyde; Medicine, Chinese Traditional; NF-KappaB Inhibitor alpha; Oxidative Stress; Plant Extracts; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Rosa; Superoxide Dismutase; Transcription Factor RelA | 2012 |
Selenium downregulates RAGE and NFκB expression in diabetic rats.
Topics: Animals; Blood Glucose; Body Weight; Diabetes Mellitus, Experimental; Dose-Response Relationship, Drug; Down-Regulation; Enzyme Activation; Female; Gene Expression Regulation; Glycated Hemoglobin; Hypoglycemic Agents; Lipid Peroxidation; Liver; Malondialdehyde; NF-kappa B; Oxidative Stress; Rats; Rats, Sprague-Dawley; Receptor for Advanced Glycation End Products; Receptors, Immunologic; Selenium; Sodium Selenite; Streptozocin | 2012 |
Ameliorative effect of berberine on renal damage in rats with diabetes induced by high-fat diet and streptozotocin.
Topics: Animals; Berberine; Blood Glucose; Body Weight; Cholesterol; Creatinine; Diabetes Mellitus, Experimental; Diet, High-Fat; Glycation End Products, Advanced; Hyperglycemia; Insulin; Intracellular Signaling Peptides and Proteins; Kidney; Kidney Function Tests; Lipid Metabolism; Male; Malondialdehyde; Membrane Proteins; Protective Agents; Rats; Rats, Sprague-Dawley; Streptozocin; Superoxide Dismutase | 2012 |
The hypoglycemic effect of the kelp on diabetes mellitus model induced by alloxan in rats.
Topics: Animals; Antioxidants; Blood Glucose; Diabetes Mellitus, Experimental; Glutathione Peroxidase; Hypoglycemic Agents; Insulin; Islets of Langerhans; Kelp; Laminaria; Male; Malondialdehyde; Nitric Oxide; Nitric Oxide Synthase Type II; Oxidative Stress; Phytotherapy; Rats; Rats, Wistar; Superoxide Dismutase | 2012 |
Effect of testosterone and frequent low-dose sildenafil/tadalafil on cavernous tissue oxidative stress of aged diabetic rats.
Topics: Aging; Animals; Carbolines; Cyclic GMP; Diabetes Mellitus, Experimental; Erectile Dysfunction; Glutathione Peroxidase; Male; Malondialdehyde; Oxidative Stress; Penile Erection; Penis; Piperazines; Purines; Rats; Rats, Sprague-Dawley; Sildenafil Citrate; Sulfones; Tadalafil; Testosterone; Vasodilator Agents | 2012 |
[Effects of alpha-linolenic acid on inflammation and oxidative stress in the diabetic rats].
Topics: alpha-Linolenic Acid; Animals; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Inflammation; Male; Malondialdehyde; Oxidative Stress; Rats; Rats, Sprague-Dawley; Superoxide Dismutase; Tumor Necrosis Factor-alpha | 2012 |
The effects of long-term administration of tadalafil on STZ-induced diabetic rats with erectile dysfunction via a local antioxidative mechanism.
Topics: Animals; Antioxidants; Blood Pressure; Carbolines; Diabetes Mellitus, Experimental; Erectile Dysfunction; Male; Malondialdehyde; Membrane Potential, Mitochondrial; Mitochondria, Muscle; Penis; Phosphodiesterase 5 Inhibitors; Rats; Rats, Sprague-Dawley; Streptozocin; Superoxide Dismutase; Tadalafil | 2012 |
Chronic administration of daidzein, a soybean isoflavone, improves endothelial dysfunction and attenuates oxidative stress in streptozotocin-induced diabetic rats.
Topics: Animals; Aorta; Diabetes Mellitus, Experimental; Endothelium, Vascular; Glycine max; Isoflavones; Male; Malondialdehyde; Oxidative Stress; Rats; Rats, Wistar; Superoxide Dismutase | 2013 |
Radix Astragali lowers kidney oxidative stress in diabetic rats treated with insulin.
Topics: Animals; Astragalus Plant; Blood Glucose; Blotting, Western; Body Weight; Creatinine; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Electrophoretic Mobility Shift Assay; Glutathione Peroxidase; Hypoglycemic Agents; Insulin; Interleukin-6; Kidney; Male; Malondialdehyde; Oxidative Stress; Plant Extracts; Rats; Rats, Wistar; Superoxide Dismutase; Tumor Necrosis Factor-alpha | 2012 |
Lycopene ameliorates erectile dysfunction in streptozotocin-induced diabetic rats.
Topics: Animals; Antioxidants; Blood Glucose; Blood Pressure; Blotting, Western; Body Weight; Carotenoids; Diabetes Mellitus, Experimental; Erectile Dysfunction; Lycopene; Male; Malondialdehyde; Nitric Oxide Synthase Type III; Oxidative Stress; Penis; Rats; Rats, Sprague-Dawley; Real-Time Polymerase Chain Reaction; Regional Blood Flow; Superoxide Dismutase | 2012 |
Comparison of oxidant/antioxidant, detoxification systems in various tissue homogenates and mitochondria of rats with diabetes induced by streptozocin.
Topics: Animals; Antioxidants; Catalase; Diabetes Mellitus, Experimental; Female; Glutathione; Kidney; Lipid Peroxidation; Liver; Lung; Male; Malondialdehyde; Mitochondria; Myocardium; Oxidative Stress; Rats; Rats, Wistar | 2012 |
Effects of Crataegus microphylla on vascular dysfunction in streptozotocin-induced diabetic rats.
Topics: Animals; Aorta; Crataegus; Diabetes Mellitus, Experimental; Endothelium, Vascular; Interleukin-6; Lipid Peroxidation; Male; Malondialdehyde; Nitrates; Nitric Oxide Synthase Type II; Nitrites; Plant Extracts; Rats; Tumor Necrosis Factor-alpha; Vasodilation; Vasodilator Agents | 2013 |
Effect of zinc supplementation on type 2 diabetes parameters and liver metallothionein expressions in Wistar rats.
Topics: Animals; Blood Glucose; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Dietary Supplements; Hypoglycemic Agents; Insulin; Lipids; Liver; Male; Malondialdehyde; Metallothionein; Oxidative Stress; Rats; Rats, Wistar; Zinc | 2012 |
Perindopril protects against streptozotocin-induced hyperglycemic myocardial damage/alterations.
Topics: Animals; Animals, Newborn; Blood Glucose; Cardiomegaly; Cardiotonic Agents; Diabetes Mellitus, Experimental; Female; Glutathione; Hemodynamics; Lipids; Male; Malondialdehyde; Oxidative Stress; Perindopril; Rats; Rats, Wistar | 2012 |
Antidiabetic effects of Corni Fructus extract in streptozotocin-induced diabetic rats.
Topics: Animals; Blotting, Western; Body Weight; Catalase; Cornus; Diabetes Mellitus, Experimental; Glucose Tolerance Test; Glutathione; Hypoglycemic Agents; Male; Malondialdehyde; Plant Extracts; Rats; Rats, Wistar; Reverse Transcriptase Polymerase Chain Reaction; Superoxide Dismutase | 2012 |
Renal protection of in vivo administration of tempol in streptozotocin-induced diabetic rats.
Topics: Animals; Antioxidants; Blood Glucose; Collagen Type IV; Cyclic N-Oxides; Diabetes Mellitus, Experimental; Glutathione Peroxidase; Kidney; Male; Malondialdehyde; Rats; Rats, Sprague-Dawley; RNA, Messenger; Spin Labels; Superoxide Dismutase; Transforming Growth Factor beta; TRPC Cation Channels | 2012 |
Antioxidant treatment with edaravone or taurine ameliorates diabetes-induced testicular dysfunction in the rat.
Topics: 8-Hydroxy-2'-Deoxyguanosine; Animals; Antioxidants; Antipyrine; Deoxyguanosine; Diabetes Complications; Diabetes Mellitus, Experimental; DNA Fragmentation; Edaravone; Lipid Peroxidation; Male; Malondialdehyde; Oxidative Stress; Rats; Rats, Wistar; Reactive Oxygen Species; Taurine; Testicular Diseases; Testis | 2012 |
Acute knockdown of uncoupling protein-2 increases uncoupling via the adenine nucleotide transporter and decreases oxidative stress in diabetic kidneys.
Topics: Adenosine Diphosphate; Animals; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Gene Knockdown Techniques; Guanosine Diphosphate; Ion Channels; Kidney Cortex; Male; Malondialdehyde; Membrane Potential, Mitochondrial; Mitochondria; Mitochondrial ADP, ATP Translocases; Mitochondrial Proteins; Oxidative Stress; Oxygen; Rats; Rats, Sprague-Dawley; Uncoupling Protein 2 | 2012 |
[Icariin reduces mitochondrial oxidative stress injury in diabetic rat hearts].
Topics: Animals; Body Weight; Collagen; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Diabetic Cardiomyopathies; Drugs, Chinese Herbal; Enteral Nutrition; Flavonoids; Heart Ventricles; Male; Malondialdehyde; Mitochondria, Heart; Organ Size; Oxidative Stress; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Streptozocin; Superoxide Dismutase | 2011 |
Ameliorative effects of resveratrol on liver injury in streptozotocin-induced diabetic rats.
Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Blood Glucose; Diabetes Mellitus, Experimental; Lipid Peroxidation; Lipids; Liver; Liver Diseases; Male; Malondialdehyde; Organ Size; Oxidative Stress; Rats; Rats, Sprague-Dawley; Resveratrol; Stilbenes; Streptozocin | 2012 |
[Effects of two different extracts of total saponins from Cicer arietinum on kidney of T2DM rats].
Topics: 6-Ketoprostaglandin F1 alpha; Angiotensin II; Animals; Blood Glucose; Blood Urea Nitrogen; Cicer; Creatinine; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Endothelin-1; Glutathione Peroxidase; Hypoglycemic Agents; Insulin; Kidney; Male; Malondialdehyde; Plants, Medicinal; Random Allocation; Rats; Rats, Wistar; Saponins; Superoxide Dismutase; Thromboxane B2 | 2012 |
Ginkgo biloba L. extract enhances the effectiveness of syngeneic bone marrow mesenchymal stem cells in lowering blood glucose levels and reversing oxidative stress.
Topics: Animals; Antioxidants; Apoptosis; Blood Glucose; Bone Marrow Cells; Cell- and Tissue-Based Therapy; Cells, Cultured; Diabetes Mellitus, Experimental; Disease Models, Animal; Ginkgo biloba; Hydrogen Peroxide; Male; Malondialdehyde; Mesenchymal Stem Cells; Oxidative Stress; Plant Extracts; Rats; Rats, Wistar; Streptozocin; Superoxide Dismutase | 2013 |
Changes in the expression of cardiac mitofusin-2 in different stages of diabetes in rats.
Topics: Animals; Apoptosis; Blood Glucose; Body Weight; Caspase 3; Diabetes Mellitus, Experimental; GTP Phosphohydrolases; Male; Malondialdehyde; Membrane Proteins; Mitochondrial Proteins; Myocardium; Rats; Rats, Sprague-Dawley; Superoxide Dismutase; Time Factors | 2012 |
GC-MS analysis and screening of antidiabetic, antioxidant and hypolipidemic potential of Cinnamomum tamala oil in streptozotocin induced diabetes mellitus in rats.
Topics: Acrolein; Administration, Oral; Animals; Antioxidants; Biomarkers; Blood Glucose; Cinnamomum; Diabetes Mellitus, Experimental; Disease Models, Animal; Gas Chromatography-Mass Spectrometry; Glutathione; Glycated Hemoglobin; Hypoglycemic Agents; Hypolipidemic Agents; Insulin; Lipids; Liver; Male; Malondialdehyde; Oils, Volatile; Plant Leaves; Plant Oils; Rats; Rats, Wistar; Time Factors | 2012 |
Treatment with Azadirachta indica in diabetic pregnant rats: negative effects on maternal outcome.
Topics: Animals; Azadirachta; Diabetes Mellitus, Experimental; Female; Fetal Development; Fetal Resorption; Glucose Tolerance Test; Glycerides; Limonins; Lipid Metabolism; Lipid Peroxidation; Malondialdehyde; Pregnancy; Pregnancy in Diabetics; Pregnancy Outcome; Rats; Seeds; Terpenes | 2012 |
Curcumin attenuates testicular damage, apoptotic germ cell death, and oxidative stress in streptozotocin-induced diabetic rats.
Topics: Animals; Antioxidants; Apoptosis; Blood Glucose; Cell Proliferation; Curcumin; Diabetes Mellitus, Experimental; Germ Cells; Glutathione Peroxidase; In Situ Nick-End Labeling; Male; Malondialdehyde; Organ Size; Oxidative Stress; Rats; Rats, Wistar; Streptozocin; Superoxide Dismutase; Testis; Testosterone | 2013 |
Insulin-induced recurrent hypoglycemia exacerbates diabetic brain mitochondrial dysfunction and oxidative imbalance.
Topics: Aconitate Hydratase; alpha-Tocopherol; Animals; Brain; Caspase 9; Diabetes Mellitus, Experimental; Energy Metabolism; Glutathione; Glutathione Disulfide; Glutathione Peroxidase; Hypoglycemia; Hypoglycemic Agents; Insulin; Male; Malondialdehyde; Mitochondria; Random Allocation; Rats, Wistar; Superoxide Dismutase; Synaptophysin | 2013 |
Assessment of antidiabetogenic potential of fermented soybean extracts in streptozotocin-induced diabetic rat.
Topics: Animals; Antioxidants; Aorta; Bacillus subtilis; Blood Glucose; Body Weight; Catalase; Diabetes Mellitus, Experimental; Drinking; Fermentation; Glutathione Peroxidase; Glycine max; Hypoglycemic Agents; In Vitro Techniques; Male; Malondialdehyde; Norepinephrine; Oxidative Stress; Plant Extracts; Rats; Rats, Wistar; Reactive Oxygen Species; Streptozocin; Superoxide Dismutase; Vasodilator Agents | 2012 |
Dose-dependent effect in the inhibition of oxidative stress and anticlastogenic potential of ginger in STZ induced diabetic rats.
Topics: Animals; Blood Glucose; Diabetes Mellitus, Experimental; DNA Damage; Dose-Response Relationship, Drug; Down-Regulation; Glutathione; Humans; Hypoglycemic Agents; Lipid Metabolism; Male; Malondialdehyde; Oxidative Stress; Plant Extracts; Rats; Rats, Wistar; Zingiber officinale | 2012 |
Salvianolic acid A protects the peripheral nerve function in diabetic rats through regulation of the AMPK-PGC1α-Sirt3 axis.
Topics: AMP-Activated Protein Kinase Kinases; Animals; Blood Glucose; Body Weight; Caffeic Acids; Diabetes Mellitus, Experimental; Diabetic Neuropathies; Glycation End Products, Advanced; Lactates; Malondialdehyde; Nitric Oxide Synthase Type I; Peripheral Nerves; Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha; Protein Kinases; Protein Serine-Threonine Kinases; Rats; RNA-Binding Proteins; Salvia miltiorrhiza; Sciatic Nerve; Sirtuin 3; Streptozocin; Superoxide Dismutase; Transcription Factors | 2012 |
Hippocampal heat shock protein 25 expression in streptozotocin-induced diabetic mice.
Topics: Animals; Blood Glucose; Body Weight; Diabetes Mellitus, Experimental; Disease Models, Animal; Gene Expression Regulation; Glial Fibrillary Acidic Protein; Hippocampus; HSP27 Heat-Shock Proteins; Male; Malondialdehyde; Mice; Mice, Inbred C57BL; Nitric Oxide Synthase Type II; Oxidative Stress; Streptozocin; Superoxide Dismutase | 2012 |
Oral administration of puerh tea polysaccharides lowers blood glucose levels and enhances antioxidant status in alloxan-induced diabetic mice.
Topics: Administration, Oral; Animals; Antioxidants; Blood Glucose; Diabetes Mellitus, Experimental; Hypoglycemic Agents; Liver; Male; Malondialdehyde; Metformin; Mice; Mice, Inbred ICR; Oxidative Stress; Plant Extracts; Polysaccharides; Superoxide Dismutase; Tea | 2012 |
The effect of copper deficiency on fetal growth and liver anti-oxidant capacity in the Cohen diabetic rat model.
Topics: Animals; Catalase; Copper; Diabetes Mellitus, Experimental; Female; Fetal Growth Retardation; Fetus; Immunohistochemistry; Linear Models; Litter Size; Liver; Malondialdehyde; Oxidative Stress; Pregnancy; Rats; Rats, Wistar; Superoxide Dismutase | 2012 |
Protective effect of ethyl pyruvate on liver injury in streptozotocin-induced diabetic rats.
Topics: Animals; Diabetes Mellitus, Experimental; Hepatocytes; Liver; Male; Malondialdehyde; Oxidative Stress; Pyruvates; Rats; Rats, Wistar; Streptozocin | 2012 |
Hesperidin prevents retinal and plasma abnormalities in streptozotocin-induced diabetic rats.
Topics: Aldehyde Reductase; Angiogenesis Inhibitors; Animals; Anti-Inflammatory Agents; Antioxidants; Blood Glucose; Blood-Retinal Barrier; Diabetes Mellitus, Experimental; Diabetic Retinopathy; Glycation End Products, Advanced; Hesperidin; Intercellular Adhesion Molecule-1; Interleukin-1beta; Male; Malondialdehyde; Oxidative Stress; Rats; Rats, Sprague-Dawley; Retina; Streptozocin; Superoxide Dismutase; Tumor Necrosis Factor-alpha; Vascular Endothelial Growth Factor A | 2012 |
In vitro antioxidant effects of Aloe barbadensis Miller extracts and the potential role of these extracts as antidiabetic and antilipidemic agents on streptozotocin-induced type 2 diabetic model rats.
Topics: Aloe; Animals; Biphenyl Compounds; Blood Glucose; Cholesterol; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Erythrocytes; Female; Free Radical Scavengers; Free Radicals; Hypoglycemic Agents; Hypolipidemic Agents; Insulin; Lipoproteins, HDL; Lipoproteins, LDL; Malondialdehyde; Picrates; Plant Extracts; Plant Leaves; Rats; Rats, Long-Evans; Streptozocin; Triglycerides | 2012 |
Preventive effect of phycocyanin from Spirulina platensis on alloxan-injured mice.
Topics: Alloxan; Animals; Blood Proteins; Diabetes Mellitus, Experimental; Glucokinase; Glycated Serum Proteins; Glycoproteins; Islets of Langerhans; Liver; Male; Malondialdehyde; Mice; Pancreas; Phycocyanin; Protective Agents; Spirulina; Triglycerides; Tumor Suppressor Protein p53 | 2012 |
Protective effect of cinnamon polyphenols against STZ-diabetic mice fed high-sugar, high-fat diet and its underlying mechanism.
Topics: Animals; Blood Glucose; Cinnamomum zeylanicum; Diabetes Mellitus, Experimental; Diet, High-Fat; Glutathione Peroxidase; Hypoglycemic Agents; Insulin; Insulin-Secreting Cells; Lipids; Male; Malondialdehyde; Mice; NF-kappa B; Nitric Oxide Synthase Type II; Oxidative Stress; Pancreas; Polyphenols; Streptozocin; Superoxide Dismutase | 2013 |
Antihyperglycemic, antilipid peroxidation, and insulin secretory activities of Otostegia persica shoot extract in streptozotocin-induced diabetic rats and in vitro C187 pancreatic β-cells.
Topics: Administration, Oral; Animals; Antioxidants; Blood Glucose; Cell Line, Tumor; Diabetes Mellitus, Experimental; Dose-Response Relationship, Drug; Gas Chromatography-Mass Spectrometry; Glutathione; Hypoglycemic Agents; Insulin; Insulin Secretion; Insulin-Secreting Cells; Lamiaceae; Lipid Peroxidation; Liver; Male; Malondialdehyde; Methanol; Plant Extracts; Plant Shoots; Plants, Medicinal; Rats; Rats, Wistar; Solvents; Streptozocin; Time Factors | 2013 |
Rhizome of Anemarrhena asphodeloides counteracts diabetic ophthalmopathy progression in streptozotocin-induced diabetic rats.
Topics: Anemarrhena; Animals; Blood Glucose; Cataract; Diabetes Mellitus, Experimental; Diabetic Retinopathy; Glucosides; Glutathione Peroxidase; Glycation End Products, Advanced; Insulin; Lens, Crystalline; Male; Malondialdehyde; Pericytes; Plant Extracts; Rats; Rats, Wistar; Retina; Rhizome; Sorbitol; Streptozocin; Superoxide Dismutase; Xanthones | 2013 |
Endothelial dysfunction, macrophage infiltration and NADPH oxidase-dependent superoxide production were attenuated by erythropoietin in streptozotocin-induced diabetic rat aorta.
Topics: Animals; Aorta; Blood Glucose; Chemokine CCL2; Diabetes Mellitus, Experimental; Endothelium, Vascular; Erythropoietin; Hemoglobins; Humans; In Vitro Techniques; Intercellular Adhesion Molecule-1; Macrophages; Male; Malondialdehyde; NADPH Oxidases; Nitrogen Oxides; Osteopontin; Rats; Rats, Wistar; Receptor for Advanced Glycation End Products; Receptors, Immunologic; Recombinant Proteins; RNA, Messenger; Superoxides; Vascular Cell Adhesion Molecule-1; Vasodilation | 2013 |
[The role of JNK in apoptosis of renal tubular epithelial cells in diabetic rats with fluctuant high blood glucose].
Topics: Animals; Apoptosis; Blood Glucose; Diabetes Mellitus, Experimental; Epithelial Cells; Kidney Tubules; Male; Malondialdehyde; MAP Kinase Kinase 4; MAP Kinase Signaling System; NADPH Oxidase 4; NADPH Oxidases; Rats; Rats, Sprague-Dawley; Superoxide Dismutase | 2012 |
[Protection effect and mechanism of Compound Xueshuantong Capsule on diabetic nephropathy rats].
Topics: Animals; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Drugs, Chinese Herbal; Male; Malondialdehyde; Matrix Metalloproteinase 2; Nitric Oxide; Oxidative Stress; Proteinuria; Rats; Rats, Sprague-Dawley; Superoxide Dismutase | 2012 |
Retinal not systemic oxidative and inflammatory stress correlated with VEGF expression in rodent models of insulin resistance and diabetes.
Topics: 8-Hydroxy-2'-Deoxyguanosine; Animals; Biomarkers; C-Reactive Protein; CD11b Antigen; CD11c Antigen; Deoxyguanosine; Diabetes Mellitus, Experimental; Diabetic Retinopathy; Enzyme-Linked Immunosorbent Assay; Inflammation; Insulin Resistance; Male; Malondialdehyde; Mice; Mice, Inbred C57BL; NF-kappa B; Obesity; Oxidative Stress; Rats; Rats, Sprague-Dawley; Rats, Zucker; Retina; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Stress, Physiological; Vascular Endothelial Growth Factor A | 2012 |
Anti-diabetic activity of chromium picolinate and biotin in rats with type 2 diabetes induced by high-fat diet and streptozotocin.
Topics: Adipose Tissue; Animals; Biotin; Blood Glucose; Diabetes Mellitus, Experimental; Diet, High-Fat; Dietary Supplements; Hydrocortisone; Hypoglycemic Agents; Insulin; Insulin Receptor Substrate Proteins; Kidney; Lipids; Liver; Male; Malondialdehyde; Micronutrients; Muscles; NF-kappa B; Picolinic Acids; PPAR gamma; Rats; Rats, Sprague-Dawley; Streptozocin | 2013 |
Melatonin ameliorates oxidative damage in hyperglycemia-induced liver injury.
Topics: Animals; Antioxidants; Body Weight; Diabetes Mellitus, Experimental; DNA Damage; Enzyme-Linked Immunosorbent Assay; Gene Expression Regulation; Glutathione; Hyperglycemia; Lipid Peroxidation; Liver; Male; Malondialdehyde; Melatonin; Oxidative Stress; Oxygen; Protein Carbonylation; Rats; Rats, Wistar; Streptozocin; Sulfhydryl Compounds; Time Factors | 2012 |
Protective effects of hydrogen-rich saline against erectile dysfunction in a streptozotocin induced diabetic rat model.
Topics: Analysis of Variance; Animals; Blood Glucose; Blotting, Western; Diabetes Mellitus, Experimental; Disease Models, Animal; Erectile Dysfunction; Hydrogen; Immunohistochemistry; Male; Malondialdehyde; Nitric Oxide Synthase; Random Allocation; Rats; Rats, Sprague-Dawley; Real-Time Polymerase Chain Reaction; Reference Values; Sodium Chloride; Streptozocin; Treatment Outcome | 2013 |
2, 3, 5, 4'-Tetrahydroxystilbene-2-O-beta-D-glucoside improves gastrointestinal motility disorders in STZ-induced diabetic mice.
Topics: Animals; Caspase 3; Diabetes Mellitus, Experimental; Gastrointestinal Motility; Glucosides; Glutathione Peroxidase; Malondialdehyde; Mice; Nitric Oxide Synthase Type I; Oxidative Stress; Phosphorylation; Stilbenes; Streptozocin | 2012 |
Therapeutic potential of Naja naja atra venom in a rat model of diabetic nephropathy.
Topics: Animals; Body Weight; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Dose-Response Relationship, Drug; Elapid Venoms; Elapidae; Kidney; Male; Malondialdehyde; Organ Size; Rats; Rats, Wistar; Superoxide Dismutase | 2012 |
Long-term supplementation of high pigmented rice bran oil (Oryza sativa L.) on amelioration of oxidative stress and histological changes in streptozotocin-induced diabetic rats fed a high fat diet; Riceberry bran oil.
Topics: Animals; Catalase; Diabetes Mellitus, Experimental; Diet, High-Fat; Dietary Supplements; Humans; Kidney; Liver; Male; Malondialdehyde; Oryza; Oxidative Stress; Pancreas; Plant Oils; Rats; Rats, Sprague-Dawley; Rice Bran Oil; Superoxide Dismutase | 2013 |
Protective effects of captopril in diabetic rats exposed to ischemia/reperfusion renal injury.
Topics: Aldosterone; Angiotensin-Converting Enzyme Inhibitors; Animals; Captopril; Caspase 3; Creatinine; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Fas Ligand Protein; Glutathione; Heme Oxygenase (Decyclizing); Hyperglycemia; Insulin; Insulin-Secreting Cells; Islets of Langerhans; Kidney; Kidney Diseases; Male; Malondialdehyde; Microtubule-Associated Proteins; NF-kappa B; Nitric Oxide; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Survivin; Tumor Necrosis Factor-alpha | 2013 |
Beneficial effects of aminoguanidine on skin flap survival in diabetic rats.
Topics: Animals; Antioxidants; Blood Glucose; Diabetes Complications; Diabetes Mellitus, Experimental; Female; Glutathione; Glycated Hemoglobin; Guanidines; Malondialdehyde; Microcirculation; Necrosis; Nitric Oxide; Oxidative Stress; Rats; Rats, Wistar; Skin; Superoxide Dismutase; Surgical Flaps | 2012 |
Positive moderation of the hematology, plasma biochemistry and ocular indices of oxidative stress in alloxan-induced diabetic rats, by an aqueous extract of the leaves of Sansevieria liberica Gerome and Labroy.
Topics: Animals; Ascorbic Acid; Blood Glucose; Diabetes Mellitus, Experimental; Diabetic Retinopathy; Electrolytes; Eye; Lipids; Malondialdehyde; Oxidative Stress; Plant Extracts; Plant Leaves; Rats; Rats, Wistar; Sansevieria | 2013 |
Serum IGF-1 levels correlate negatively to liver damage in diabetic rats.
Topics: Alanine Transaminase; Animals; Blood Glucose; Diabetes Mellitus, Experimental; Female; Glutathione; Glutathione Peroxidase; Insulin-Like Growth Factor I; Liver; Malondialdehyde; Oxidative Stress; Rats; Rats, Wistar | 2013 |
Effect of Salvia miltiorrhiza on retinopathy.
Topics: Animals; Blood Glucose; Diabetes Mellitus, Experimental; Diabetic Retinopathy; Malondialdehyde; Mice; Plant Extracts; Random Allocation; Retina; Salvia miltiorrhiza | 2013 |
Malondialdehyde and 4-hydroxynonenal adducts are not formed on cardiac ryanodine receptor (RyR2) and sarco(endo)plasmic reticulum Ca2+-ATPase (SERCA2) in diabetes.
Topics: Aldehydes; Animals; Arginine; Calcium; Cyclic N-Oxides; Diabetes Mellitus, Experimental; Diabetic Cardiomyopathies; Echocardiography; Guanidines; Lysine; Male; Malondialdehyde; Myocytes, Cardiac; Norleucine; Protein Carbonylation; Pyridoxamine; Pyrroles; Rats; Rats, Sprague-Dawley; Ryanodine Receptor Calcium Release Channel; Sarcoplasmic Reticulum; Sarcoplasmic Reticulum Calcium-Transporting ATPases; Spin Labels | 2013 |
The effects of taurine and thiotaurine on oxidative stress in the aorta and heart of diabetic rats.
Topics: Animals; Aorta; Blood Glucose; Catalase; Cholesterol; Diabetes Mellitus, Experimental; Disease Models, Animal; Glutathione Disulfide; Glutathione Peroxidase; Insulin; Male; Malondialdehyde; Myocardium; Nitric Oxide; Nitrites; Organ Size; Oxidative Stress; Rats; Rats, Sprague-Dawley; Superoxide Dismutase; Taurine; Triglycerides; Weight Gain | 2013 |
Antioxidant therapy potentiates antihypertensive action of insulin in diabetic rats.
Topics: Animals; Antioxidants; Blood Glucose; Blood Pressure; Body Weight; Creatinine; Diabetes Mellitus, Experimental; Drug Synergism; Glutathione; Glycated Hemoglobin; Hyperglycemia; Hypertension; Hypoglycemic Agents; Insulin; Male; Malondialdehyde; Nitric Oxide; Oxidative Stress; Proteinuria; Rats; Rats, Sprague-Dawley; Tocopherols | 2002 |
Effects of alpha lipoic acid, ascorbic acid-6-palmitate, and fish oil on the glutathione, malonaldehyde, and fatty acids levels in erythrocytes of streptozotocin induced diabetic male rats.
Topics: Animals; Antioxidants; Ascorbic Acid; Cholesterol; Diabetes Mellitus, Experimental; Erythrocyte Membrane; Erythrocytes; Fatty Acids; Fish Oils; Glutathione; Lipid Peroxidation; Male; Malondialdehyde; Oxidative Stress; Rats; Rats, Wistar; Streptozocin; Thioctic Acid; Triglycerides | 2002 |
Effect of vitamin E on plasma malondialdehyde, antioxidant enzyme levels and the rates of wound closures during wound healing in normal and diabetic rats.
Topics: Administration, Oral; Animals; Antioxidants; Catalase; Diabetes Mellitus, Experimental; Glutathione Peroxidase; Male; Malondialdehyde; Random Allocation; Rats; Rats, Sprague-Dawley; Superoxide Dismutase; Time Factors; Vitamin E; Wound Healing | 2002 |
[Effects of vitamin E and vitamin C on nonenzymatic glycation and peroxidation in experimental diabetic rats].
Topics: Animals; Ascorbic Acid; Diabetes Mellitus, Experimental; Glycation End Products, Advanced; Lipid Peroxidation; Male; Malondialdehyde; Random Allocation; Rats; Rats, Sprague-Dawley; Vitamin E | 2000 |
Effect of tetramethylpyrazine on lipid peroxidation in streptozotocin-induced diabetic mice.
Topics: Animals; Blood Glucose; Blood Urea Nitrogen; Body Weight; Diabetes Mellitus, Experimental; Free Radical Scavengers; Lipid Peroxidation; Male; Malondialdehyde; Mice; Mice, Inbred ICR; Pyrazines; Thiobarbituric Acid Reactive Substances | 2002 |
Antidiabetic and antioxidant effects of S-methyl cysteine sulfoxide isolated from onions (Allium cepa Linn) as compared to standard drugs in alloxan diabetic rats.
Topics: Animals; Antioxidants; Blood Glucose; Body Weight; Catalase; Cysteine; Diabetes Mellitus, Experimental; Glucose; Glyburide; Hydrogen Peroxide; Hypoglycemic Agents; Insulin; Lipid Peroxidation; Malondialdehyde; Onions; Rats; Rats, Sprague-Dawley; Superoxide Dismutase | 2002 |
The effect of Gongronema latifolium extracts on serum lipid profile and oxidative stress in hepatocytes of diabetic rats.
Topics: Animals; Antioxidants; Apocynaceae; Catalase; Cholesterol; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Disease Models, Animal; Ethanol; Glutathione Peroxidase; Hepatocytes; Male; Malondialdehyde; Oxidative Stress; Plant Extracts; Plant Leaves; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Superoxide Dismutase; Triglycerides | 2003 |
The role of ascorbic acid on the redox status and the concentration of malondialdehyde in streptozotocin-induced diabetic rats.
Topics: Animals; Ascorbic Acid; Diabetes Mellitus, Experimental; Male; Malondialdehyde; Oxidation-Reduction; Oxidative Stress; Rats; Rats, Sprague-Dawley | 2003 |
Effects of vitamin E on microsomal Ca(2+) -ATPase activity and calcium levels in streptozotocin-induced diabetic rat kidney.
Topics: Animals; Antioxidants; Blood Glucose; Body Weight; Calcium; Calcium-Transporting ATPases; Diabetes Mellitus, Experimental; Kidney; Lipid Peroxidation; Malondialdehyde; Microsomes; Rats; Rats, Wistar; Vitamin E | 2003 |
Tocotrienols-rich diet decreases advanced glycosylation end-products in non-diabetic rats and improves glycemic control in streptozotocin-induced diabetic rats.
Topics: Animals; Ascorbic Acid; Blood Glucose; Diabetes Mellitus, Experimental; Diet; Glycated Hemoglobin; Glycation End Products, Advanced; Hypoglycemia; Hypoglycemic Agents; Male; Malondialdehyde; Rats; Rats, Sprague-Dawley; Streptozocin; Tocotrienols | 2002 |
Protective effects of chronic melatonin treatment against renal injury in streptozotocin-induced diabetic rats.
Topics: Animals; Antioxidants; Blood Glucose; Body Weight; Diabetes Mellitus, Experimental; Immunohistochemistry; Kidney; Kidney Diseases; Lipid Peroxidation; Malondialdehyde; Melatonin; Microscopy, Electron; Oxidative Stress; Rats | 2003 |
Redox changes precede the occurrence of oxidative stress in eyes and aorta, but not in kidneys of diabetic rats.
Topics: Animals; Antioxidants; Aorta, Thoracic; Blood Glucose; Blood Vessels; Diabetes Mellitus, Experimental; Diabetic Angiopathies; Eye; Glutathione; Hemoglobins; Kidney; Lipid Peroxidation; Male; Malondialdehyde; Oxidation-Reduction; Oxidative Stress; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Vitamin E | 2003 |
Modification of renal oxidative stress and lipid peroxidation in streptozotocin-induced diabetic rats treated with extracts from Gongronema latifolium leaves.
Topics: Animals; Antioxidants; Apocynaceae; Catalase; Diabetes Mellitus, Experimental; Glutathione; Glutathione Peroxidase; Kidney; Lipid Peroxidation; Male; Malondialdehyde; Oxidation-Reduction; Oxidative Stress; Plant Extracts; Plant Leaves; Rats; Rats, Wistar; Reactive Oxygen Species; Superoxide Dismutase | 2003 |
Alpha-lipoic acid treatment prevents the diabetes-induced attenuation of the afferent limb of the baroreceptor reflex in rats.
Topics: Afferent Pathways; Animals; Baroreflex; Diabetes Mellitus, Experimental; Genes, fos; Male; Malondialdehyde; Rats; Rats, Sprague-Dawley; Thioctic Acid | 2003 |
Antioxidant activity of a Schiff base of pyridoxal and aminoguanidine.
Topics: Animals; Antioxidants; Ascorbic Acid; Aspartate Aminotransferases; Benzoates; Blood Glucose; Body Weight; Chromatography, High Pressure Liquid; Cytochrome P-450 Enzyme System; Diabetes Mellitus; Diabetes Mellitus, Experimental; Dose-Response Relationship, Drug; Erythrocytes; Fluorescent Dyes; Guanidines; Hydrogen Peroxide; Ions; Lipid Peroxidation; Lipoproteins, LDL; Liver; Magnetic Resonance Spectroscopy; Male; Malondialdehyde; Mass Spectrometry; Mice; Microsomes, Liver; Models, Chemical; Oxidants; Oxygen; Pyridoxal; Rats; Rats, Wistar; Reactive Oxygen Species; Spectrophotometry; Spectrophotometry, Infrared; Superoxides; Time Factors | 2003 |
[Effect of iron on peroxidation and non-enzymatic glycation in diabetic rats].
Topics: Animals; Diabetes Mellitus, Experimental; Glycation End Products, Advanced; Iron; Lipid Peroxidation; Male; Malondialdehyde; Rats; Rats, Sprague-Dawley | 2003 |
Effect of vitamin E and vitamin C supplementation on antioxidative state and renal glomerular basement membrane thickness in diabetic kidney.
Topics: Albuminuria; Animals; Antioxidants; Ascorbic Acid; Basement Membrane; Blood Glucose; Body Weight; Catalase; Diabetes Mellitus, Experimental; Dietary Supplements; Glomerular Mesangium; Glutathione Peroxidase; Glycated Hemoglobin; Male; Malondialdehyde; Organ Size; Rats; Rats, Wistar; Superoxide Dismutase; Time Factors; Vitamin E | 2003 |
Relationship between malondialdehyde level and glutathione peroxidase activity in diabetic rats.
Topics: Animals; Antioxidants; Blood Glucose; Body Weight; Diabetes Mellitus, Experimental; Glutathione Peroxidase; Male; Malondialdehyde; Oxidative Stress; Rats; Rats, Wistar; Spectrophotometry | 2004 |
In vivo measurement of redox status in streptozotocin-induced diabetic rat using targeted nitroxyl probes.
Topics: Animals; Cell Membrane; Cyclic N-Oxides; Diabetes Mellitus, Experimental; Electron Spin Resonance Spectroscopy; Free Radicals; Malondialdehyde; Nitrogen; Oxidation-Reduction; Pyrrolidines; Rats; Signal Transduction; Streptozocin; Time Factors; Xanthine Oxidase | 2004 |
Moderate exercise with a dietary vitamin C and E combination protects against streptozotocin-induced oxidative damage to the blood and improves fetal outcomes in pregnant rats.
Topics: Animals; Ascorbic Acid; beta Carotene; Blood; Blood Cell Count; Blood Glucose; Body Weight; Catalase; Diabetes Mellitus, Experimental; Dietary Supplements; Erythrocytes; Female; Glutathione; Glutathione Peroxidase; Lipid Peroxidation; Litter Size; Malondialdehyde; Oxidative Stress; Physical Conditioning, Animal; Pregnancy; Rats; Rats, Wistar; Vitamin A; Vitamin E | 2004 |
A study on the effects to diabetic nephropathy of Hachimi-jio-gan in rats.
Topics: Administration, Oral; Animals; Blood Glucose; Body Weight; Creatinine; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Disease Models, Animal; Drugs, Chinese Herbal; Glycation End Products, Advanced; Kidney; Male; Malondialdehyde; Proteinuria; Rats; Rats, Wistar; Sorbitol; Streptozocin | 2004 |
Effects of Nigella sativa on oxidative stress and beta-cell damage in streptozotocin-induced diabetic rats.
Topics: Animals; Blood Glucose; Diabetes Mellitus, Experimental; Immunohistochemistry; Insulin; Islets of Langerhans; Male; Malondialdehyde; Nigella sativa; Nitric Oxide; Oxidative Stress; Oxidoreductases; Pancreas; Plant Oils; Rats; Rats, Wistar; Staining and Labeling | 2004 |
Exercise training prevents and protects streptozotocin-induced oxidative stress and beta-cell damage in rat pancreas.
Topics: Animals; Antioxidants; Blood Glucose; Body Weight; Catalase; Diabetes Mellitus, Experimental; Glutathione Peroxidase; Immunohistochemistry; Insulin; Islets of Langerhans; Lipid Peroxidation; Male; Malondialdehyde; Nitric Oxide; Oxidative Stress; Pancreas; Physical Conditioning, Animal; Rats; Rats, Wistar; Streptozocin; Superoxide Dismutase; Time Factors | 2004 |
[Changes of SOD, GSH and MDA in renal tissues of diabetic hyperlipidemia rats].
Topics: Animals; Diabetes Mellitus, Experimental; Glutathione; Hyperlipidemias; Insulin Resistance; Kidney; Male; Malondialdehyde; Rats; Rats, Wistar; Streptozocin; Superoxide Dismutase | 2004 |
The effects of dietary caloric restriction on antioxidant status and lipid peroxidation in mild and severe streptozotocin-induced diabetic rats.
Topics: Animals; Antioxidants; Blood Glucose; Body Weight; Caloric Restriction; Catalase; Cholesterol, HDL; Diabetes Mellitus, Experimental; Glutathione Peroxidase; Glycated Hemoglobin; Lipid Peroxidation; Male; Malondialdehyde; Oxidative Stress; Rats; Rats, Wistar; Severity of Illness Index; Superoxide Dismutase; Triglycerides | 2004 |
Effects of dietary long chain PUFAs on hippocampal lipid peroxidation and NMDA receptor subunits A and B concentration in streptozotocin-diabetic rats.
Topics: Animals; Blood Glucose; Blotting, Western; Body Weight; Diabetes Mellitus, Experimental; Dietary Fats, Unsaturated; Fatty Acids, Unsaturated; Hippocampus; Lipid Peroxidation; Malondialdehyde; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Statistics, Nonparametric | 2004 |
Melatonin treatment protects against diabetes-induced functional and biochemical changes in rat aorta and corpus cavernosum.
Topics: Acetylcholine; Animals; Aorta, Thoracic; Blood Glucose; Body Weight; Diabetes Mellitus, Experimental; Dose-Response Relationship, Drug; Glutathione; In Vitro Techniques; Insulin; Lipid Peroxidation; Male; Malondialdehyde; Melatonin; Muscle Contraction; Muscle Relaxation; Nitroprusside; Papaverine; Penis; Phenylephrine; Rats; Rats, Wistar; Time Factors; Vasoconstriction; Vasoconstrictor Agents; Vasodilation; Vasodilator Agents | 2004 |
Protective effect of caffeic acid phenethyl ester (CAPE) on lipid peroxidation and antioxidant enzymes in diabetic rat liver.
Topics: Animals; Antioxidants; Caffeic Acids; Catalase; Diabetes Mellitus, Experimental; Glutathione Peroxidase; Lipid Peroxidation; Liver; Male; Malondialdehyde; Phenylethyl Alcohol; Rats; Rats, Sprague-Dawley; Superoxide Dismutase | 2004 |
Effects of caffeic acid phenethyl ester on lipid peroxidation and antioxidant enzymes in diabetic rat heart.
Topics: Animals; Antioxidants; Caffeic Acids; Diabetes Mellitus, Experimental; Lipid Peroxidation; Male; Malondialdehyde; Myocardium; Oxidative Stress; Oxidoreductases; Phenylethyl Alcohol; Rats; Rats, Sprague-Dawley | 2005 |
Early changes in glial reactivity and lipid peroxidation in diabetic rat retina: effects of melatonin.
Topics: Animals; Blood Glucose; Cholesterol; Diabetes Mellitus, Experimental; Glial Fibrillary Acidic Protein; Lipid Peroxidation; Male; Malondialdehyde; Melatonin; Neuroglia; Rats; Rats, Wistar; Retina; Triglycerides | 2004 |
Effect of the pyridoindole antioxidant stobadine on development of experimental diabetic cataract and on lens protein oxidation in rats: comparison with vitamin E and BHT.
Topics: Animals; Antioxidants; Blood Glucose; Body Weight; Butylated Hydroxytoluene; Carbolines; Cataract; Crystallins; Diabetes Mellitus, Experimental; Dietary Supplements; Disease Progression; Drug Combinations; Lens, Crystalline; Male; Malondialdehyde; Oxidation-Reduction; Rats; Rats, Wistar; Vitamin E | 2005 |
Rapid monitoring of diabetes-induced lipid peroxidation by Fourier transform infrared spectroscopy: evidence from rat liver microsomal membranes.
Topics: Animals; Cell Membrane; Diabetes Mellitus, Experimental; Lipid Peroxidation; Male; Malondialdehyde; Microsomes, Liver; Monitoring, Physiologic; Rats; Rats, Wistar; Spectroscopy, Fourier Transform Infrared; Temperature; Thiobarbituric Acid Reactive Substances | 2005 |
Novel role for gabapentin in neuroprotection of central nervous system in streptozotocine-induced diabetic rats.
Topics: Amines; Animals; Brain; Cyclohexanecarboxylic Acids; Diabetes Mellitus, Experimental; Gabapentin; gamma-Aminobutyric Acid; Glial Fibrillary Acidic Protein; Glutathione; Lipid Peroxidation; Male; Malondialdehyde; Nerve Growth Factors; Neuroprotective Agents; Phosphopyruvate Hydratase; Random Allocation; Rats; Rats, Wistar; S100 Calcium Binding Protein beta Subunit; S100 Proteins | 2005 |
The effects of Ananas comosus L. leaves on diabetic-dyslipidemic rats induced by alloxan and a high-fat/high-cholesterol diet.
Topics: Ananas; Animals; Cholesterol, Dietary; Diabetes Mellitus, Experimental; Dietary Fats; Drugs, Chinese Herbal; Glucose Tolerance Test; Hyperlipidemias; Lipid Peroxidation; Male; Malondialdehyde; Plant Leaves; Rats; Rats, Wistar | 2005 |
Attenuation of endothelial dysfunction by exercise training in STZ-induced diabetic rats.
Topics: Acetylcholine; Animals; Antioxidants; Arteries; Blood Glucose; Blood Pressure; Cell Adhesion; Diabetes Complications; Diabetes Mellitus, Experimental; Endothelium, Vascular; Glycated Hemoglobin; Leukocytes; Male; Malondialdehyde; Mesenteric Arteries; Microcirculation; Microscopy, Fluorescence; Nitroprusside; Organ Size; Oxidants; Oxidative Stress; Physical Conditioning, Animal; Rats; Rats, Sprague-Dawley; Streptozocin; Time Factors; Vasodilation; Vasodilator Agents | 2005 |
A study of hypoglycemic and antioxidant activity of Aegle marmelos in alloxan induced diabetic rats.
Topics: Aegle; Alloxan; Animals; Antioxidants; Blood Glucose; Diabetes Mellitus, Experimental; Glutathione; Hypoglycemic Agents; Male; Malondialdehyde; Plant Extracts; Rats | 2004 |
Effects of STZ-induced diabetes and its treatment with vanadyl sulphate on cyclosporine A-induced nephrotoxicity in rats.
Topics: Animals; Cyclosporine; Diabetes Mellitus, Experimental; Glutathione; Hypoglycemic Agents; Immunosuppressive Agents; Kidney; Kidney Diseases; Kidney Function Tests; Male; Malondialdehyde; Organ Size; Rats; Rats, Wistar; Vanadium Compounds | 2005 |
Diltiazem attenuates oxidative stress in diabetic rats.
Topics: Animals; Antibiotics, Antineoplastic; Biomarkers; Blood Glucose; Calcium Channel Blockers; Catalase; Creatinine; Diabetes Mellitus, Experimental; Diltiazem; Follow-Up Studies; Glutathione; Kidney; Lipid Peroxidation; Male; Malondialdehyde; Nitrites; Oxidative Stress; Rats; Rats, Wistar; Streptozocin; Superoxide Dismutase; Treatment Outcome | 2005 |
Age-related differences in the degree of lipid peroxidation and state of antioxidant protection under the influence of alloxan.
Topics: Aging; Alloxan; Animals; Antioxidants; Diabetes Mellitus, Experimental; Hyperglycemia; Hyperlipidemias; Lipid Peroxidation; Male; Malondialdehyde; Oxidation-Reduction; Oxidative Stress; Rats; Rats, Wistar | 2005 |
Protective effect of polyphenol-containing azuki bean (Vigna angularis) seed coats on the renal cortex in streptozotocin-induced diabetic rats.
Topics: Animals; Blood Glucose; Chemokine CCL2; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Fabaceae; Flavonoids; Kidney Cortex; Macrophages; Male; Malondialdehyde; Phenols; Polyphenols; Protective Agents; Rats; Rats, Wistar; RNA, Messenger; Seeds; Streptozocin | 2005 |
Effect of the joint administration of selenium and vitamin E in combination with regular aerobic exercise on markers of lipid peroxidation and glutathione peroxidase in diabetic rats.
Topics: Animals; Antioxidants; Diabetes Mellitus, Experimental; Drug Synergism; Glutathione Peroxidase; Lipid Peroxidation; Lipoproteins, LDL; Male; Malondialdehyde; Oxidative Stress; Physical Conditioning, Animal; Random Allocation; Rats; Rats, Sprague-Dawley; Selenium; Vitamin E | 2005 |
Preventing and treating actions of compound lian zhu capsule on micrangium lesions in diabetic rats.
Topics: Aldehyde Reductase; Animals; Capsules; Diabetes Complications; Diabetes Mellitus, Experimental; Drugs, Chinese Herbal; Glycated Hemoglobin; Kidney; Male; Malondialdehyde; Microcirculation; Phytotherapy; Rats; Rats, Wistar; Retina | 2005 |
Comparative effects of palm vitamin E and alpha-tocopherol on healing and wound tissue antioxidant enzyme levels in diabetic rats.
Topics: alpha-Tocopherol; Animals; Antioxidants; Diabetes Mellitus, Experimental; Enzymes; Glutathione Peroxidase; Male; Malondialdehyde; Rats; Rats, Sprague-Dawley; Skin; Superoxide Dismutase; Vitamin E; Wound Healing; Wounds, Penetrating | 2005 |
Increased glomerular and extracellular malondialdehyde levels in patients and rats with diabetic nephropathy.
Topics: Adolescent; Adult; Animals; Antibodies; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Extracellular Space; Female; Humans; Immunohistochemistry; Kidney Glomerulus; Male; Malondialdehyde; Middle Aged; Oxidative Stress; Rats; Rats, Wistar; Superoxide Dismutase | 2005 |
[Studies on the hypoglycemia and lipids regulating effects of Plantago depressa var. montata].
Topics: Animals; Blood Glucose; Blood Proteins; Cell Survival; Cells, Cultured; Cholesterol; Diabetes Mellitus, Experimental; Drugs, Chinese Herbal; Endothelial Cells; Glucose Tolerance Test; Glycated Serum Proteins; Glycoproteins; Humans; Hypoglycemic Agents; Hypolipidemic Agents; Lipids; Male; Malondialdehyde; Mice; Mice, Inbred ICR; Nitric Oxide; Pancreas; Plantago; Plants, Medicinal; Superoxide Dismutase; Umbilical Veins | 2005 |
The antihyperlipidemic activities of 4(3H) quinazolinone and two halogenated derivatives in rats.
Topics: Animals; Bezafibrate; Blood Glucose; Body Weight; Cholesterol, Dietary; Diabetes Mellitus, Experimental; Hypercholesterolemia; Hypolipidemic Agents; Lipids; Male; Malondialdehyde; Quinazolines; Quinazolinones; Rats | 2005 |
[Changes of cycle and apoptosis of spermatogenic cells and antioxidant capacity in male rats with diabetes mellitus].
Topics: Animals; Apoptosis; Cell Cycle; Diabetes Mellitus, Experimental; Male; Malondialdehyde; Nitric Oxide; Rats; Rats, Wistar; Superoxide Dismutase; Testis | 2005 |
Resveratrol, a polyphenolic phytoalexin, attenuates diabetic nephropathy in rats.
Topics: Animals; Antioxidants; Catalase; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Dose-Response Relationship, Drug; Glutathione; Kidney; Kidney Function Tests; Lipid Peroxidation; Male; Malondialdehyde; Oxidative Stress; Phenols; Phytoalexins; Phytotherapy; Plant Extracts; Rats; Rats, Sprague-Dawley; Resveratrol; Sesquiterpenes; Stilbenes; Superoxide Dismutase; Terpenes | 2006 |
Effect of prostaglandins against alloxan-induced diabetes mellitus.
Topics: Alloxan; Alprostadil; Animals; Antioxidants; Blood Glucose; Body Weight; Catalase; Ceruloplasmin; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Dinoprostone; Erythrocytes; Glutathione Peroxidase; Glutathione Transferase; Injections, Intraperitoneal; Insulin; Lactic Acid; Lipid Peroxides; Male; Malondialdehyde; Nitric Oxide; Pancreas; Prostaglandins; Prostaglandins F; Rats; Rats, Wistar; Superoxide Dismutase; Thromboxane B2 | 2006 |
Intra-ductal glutamine administration reduces oxidative injury during human pancreatic islet isolation.
Topics: Adult; Aged; Animals; Apoptosis; Cell Separation; Diabetes Mellitus, Experimental; Female; Glutamine; Glutathione; Graft Survival; Humans; In Situ Nick-End Labeling; Islets of Langerhans; Islets of Langerhans Transplantation; Male; Malondialdehyde; Mice; Mice, Nude; Middle Aged; Oxidative Stress; Pancreatic Ducts; Perfusion; Transplantation, Heterologous | 2005 |
General administration of cyclohexenonic long-chain fatty alcohol ameliorates hyperreactivity of STZ-induced diabetic rat aorta.
Topics: Acetylcholine; Animals; Aorta; Blood Glucose; Cyclohexanones; Diabetes Mellitus, Experimental; Fatty Alcohols; In Vitro Techniques; Male; Malondialdehyde; Muscle, Smooth, Vascular; Rats; Rats, Sprague-Dawley; Reference Values; Vasoconstriction; Vasodilation | 2006 |
Antidiabetic effect of a new peptide from Squalus mitsukurii liver (S-8300) in streptozocin-induced diabetic mice.
Topics: Animals; Blood Glucose; Body Weight; Cholesterol; Diabetes Mellitus, Experimental; Fatty Acids, Nonesterified; Glycated Hemoglobin; Hypoglycemic Agents; Kidney; Liver; Malondialdehyde; Mice; Mice, Inbred ICR; Organ Size; Peptides; Squalus; Streptozocin; Superoxide Dismutase; Triglycerides | 2005 |
Effect of I-deprenyl and gliclazide on oxidant stress/antioxidant status and dna damage in a diabetic rat model.
Topics: 8-Hydroxy-2'-Deoxyguanosine; Aging; Animals; Antioxidants; Blood Glucose; Body Weight; Deoxyguanosine; Diabetes Mellitus, Experimental; Disease Models, Animal; DNA Damage; Gliclazide; Hypoglycemic Agents; Lipid Peroxidation; Liver; Male; Malondialdehyde; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Oxidants; Oxidative Stress; Rats; Rats, Inbred Strains; Selegiline; Superoxide Dismutase; Vitamin A; Vitamin E | 2005 |
Differential effect of saturated, monounsaturated, and polyunsaturated fatty acids on alloxan-induced diabetes mellitus.
Topics: Alloxan; Animals; Arachidonic Acid; Blood Glucose; Body Weight; Catalase; Ceruloplasmin; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Erythrocytes; Glutathione Peroxidase; Glutathione Transferase; Indomethacin; Insulin; Kidney; Lactic Acid; Lipid Peroxides; Liver; Male; Malondialdehyde; Masoprocol; Nitric Oxide; Oleic Acid; Pancreas; Phospholipids; Rats; Rats, Wistar; Stearic Acids; Superoxide Dismutase | 2006 |
Danshen prevents the occurrence of oxidative stress in the eye and aorta of diabetic rats without affecting the hyperglycemic state.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Antioxidants; Aorta, Thoracic; Diabetes Mellitus, Experimental; Drugs, Chinese Herbal; Eye; Glutathione; Hyperglycemia; Male; Malondialdehyde; Oxidation-Reduction; Oxidative Stress; Phenanthrolines; Rats; Rats, Sprague-Dawley; Salvia miltiorrhiza; Streptozocin | 2006 |
[Oxidative stress in a model of experimental diabetic retinopathy: the utility of peroxinytrite scavengers].
Topics: Animals; Antioxidants; Diabetes Mellitus, Experimental; Diabetic Retinopathy; Disease Models, Animal; Electroretinography; Free Radical Scavengers; Glutathione; Malondialdehyde; Mice; Oxidative Stress; Peroxynitrous Acid | 2006 |
Neuroprotective effect of mexiletine in the central nervous system of diabetic rats.
Topics: Animals; Blood Glucose; Brain Stem; Central Nervous System; Cerebellum; Cerebral Cortex; Diabetes Mellitus, Experimental; Hippocampus; Injections, Intraperitoneal; Male; Malondialdehyde; Mexiletine; Neuroprotective Agents; Nitric Oxide; Rats; Rats, Wistar; Spinal Cord; Time Factors; Xanthine Oxidase | 2006 |
Edaravone attenuates hydroxyl radical stress and augmented angiotensin II response in diabetic rats.
Topics: Angiotensin II; Animals; Antipyrine; Aorta, Thoracic; Blood Pressure; Catalase; Diabetes Mellitus, Experimental; Edaravone; Free Radical Scavengers; Hydrogen Peroxide; Hydroxyl Radical; In Vitro Techniques; Lipid Peroxidation; Male; Malondialdehyde; Oxidative Stress; Rats; Rats, Sprague-Dawley; Superoxide Dismutase; tert-Butylhydroperoxide; Vasoconstriction | 2006 |
Effects of melatonin on streptozotocin-induced diabetic liver injury in rats.
Topics: Animals; Antioxidants; Blood Glucose; Body Weight; Diabetes Mellitus, Experimental; Hyperglycemia; Lipid Peroxidation; Lipid Peroxides; Liver; Liver Diseases; Male; Malondialdehyde; Melatonin; Microscopy, Electron; Oxidative Stress; Rats; Rats, Wistar; Superoxide Dismutase | 2006 |
Effects of melatonin on lipid peroxidation and antioxidant enzymes in streptozotocin-induced diabetic rat testis.
Topics: Animals; Catalase; Diabetes Mellitus, Experimental; Glutathione Peroxidase; Lipid Peroxidation; Male; Malondialdehyde; Melatonin; Rats; Rats, Sprague-Dawley; Reference Values; Superoxide Dismutase; Testis | 2006 |
Effects of vitamin C on muscle glycogen and oxidative events in experimental diabetes.
Topics: Animals; Ascorbic Acid; Blood Glucose; Body Weight; Diabetes Mellitus, Experimental; Glutathione; Glycogen; Male; Malondialdehyde; Muscle, Skeletal; Nitric Oxide; Organ Size; Oxidation-Reduction; Rats; Rats, Wistar | 2006 |
Neuroprotective effect of etomidate in the central nervous system of streptozotocin-induced diabetic rats.
Topics: Animals; Blood Glucose; Central Nervous System; Diabetes Mellitus, Experimental; Etomidate; Glutathione; Male; Malondialdehyde; Neuroprotective Agents; Oxidative Stress; Rats; Rats, Wistar; Streptozocin; Xanthine Oxidase | 2006 |
In-vivo assessment of antidiabetic and antioxidant activities of grapevine leaves (Vitis vinifera) in diabetic rats.
Topics: Animals; Antioxidants; Blood Glucose; Body Weight; Diabetes Mellitus, Experimental; Dose-Response Relationship, Drug; Glutathione; Heart; Hypoglycemic Agents; Kidney; Liver; Male; Malondialdehyde; Medicine, Traditional; Myocardium; Plant Extracts; Plant Leaves; Rats; Rats, Wistar; Streptozocin; Time Factors; Turkey; Vitis | 2006 |
Renoprotective effects of combination of angiotensin converting enzyme inhibitor with mycophenolate mofetil in diabetic rats.
Topics: Albuminuria; Angiotensin-Converting Enzyme Inhibitors; Animals; Chemokine CCL2; Diabetes Mellitus, Experimental; Drug Therapy, Combination; Enalapril; Immunosuppressive Agents; Intercellular Adhesion Molecule-1; Kidney; Macrophages; Male; Malondialdehyde; Mycophenolic Acid; Oxidative Stress; Rats; Rats, Wistar; Transforming Growth Factor beta; Transforming Growth Factor beta1 | 2006 |
Protein kinase C beta inhibitor LY333531 attenuates intercellular adhesion molecule-1 and monocyte chemotactic protein-1 expression in the kidney in diabetic rats.
Topics: Albuminuria; Animals; Blood Glucose; Blotting, Western; Body Weight; Chemokine CCL2; Diabetes Mellitus, Experimental; Immunohistochemistry; Indoles; Intercellular Adhesion Molecule-1; Kidney; Kidney Glomerulus; Macrophages; Maleimides; Malondialdehyde; Nephritis, Interstitial; Organ Size; Oxidative Stress; Peroxidases; Protein Kinase C; Protein Kinase C beta; Rats; Rats, Wistar | 2006 |
Carvedilol protected diabetic rat hearts via reducing oxidative stress.
Topics: Animals; Antioxidants; Blood Glucose; Body Weight; Carbazoles; Carvedilol; Diabetes Mellitus, Experimental; Heart; Male; Malondialdehyde; Myocytes, Cardiac; Oxidative Stress; Propanolamines; Proto-Oncogene Proteins c-bcl-2; Rats; Rats, Sprague-Dawley; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Streptozocin; Systole | 2006 |
Lutein effect on retina and hippocampus of diabetic mice.
Topics: Animals; Blood Glucose; Diabetes Mellitus, Experimental; Electroretinography; Glutathione; Hippocampus; Lutein; Male; Malondialdehyde; Maze Learning; Mice; NF-kappa B; Reference Values; Retina | 2006 |
In vivo antidiabetic and antioxidant potential of Helichrysum plicatum ssp. plicatum capitulums in streptozotocin-induced-diabetic rats.
Topics: Animals; Antioxidants; Blood Glucose; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Ethanol; Flavonoids; Glucose Tolerance Test; Glutathione; Heart; Helichrysum; Hypoglycemic Agents; Kidney; Lipid Peroxidation; Liver; Male; Malondialdehyde; Myocardium; Phytotherapy; Plant Extracts; Rats; Rats, Wistar; Solvents; Sulfhydryl Compounds; Turkey; Water | 2007 |
Curcumin, the active principle of turmeric (Curcuma longa), ameliorates diabetic nephropathy in rats.
Topics: Animals; Blood Glucose; Blood Pressure; Body Weight; Catalase; Curcuma; Curcumin; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Drug Evaluation, Preclinical; Glutathione; Kidney; Malondialdehyde; Oxidative Stress; Plant Extracts; Rats; Rats, Sprague-Dawley; Superoxide Dismutase; Survival Rate | 2006 |
Effect of docosahexaenoic acid intake on lipid peroxidation in diabetic rat retina under oxidative stress.
Topics: Animals; Antioxidants; Diabetes Mellitus, Experimental; Docosahexaenoic Acids; Free Radicals; Lipid Peroxidation; Lipid Peroxides; Malondialdehyde; Oxidative Stress; Rats; Rats, Sprague-Dawley; Retina; Vitamin E | 2006 |
Ginsenoside Re of Panax ginseng possesses significant antioxidant and antihyperlipidemic efficacies in streptozotocin-induced diabetic rats.
Topics: Animals; Antioxidants; Aorta, Thoracic; Blood Glucose; Cholesterol; Diabetes Mellitus, Experimental; Dose-Response Relationship, Drug; Eye; Ginsenosides; Glutathione; Glycated Hemoglobin; Hypolipidemic Agents; Kidney; Lipids; Male; Malondialdehyde; Oxidative Stress; Panax; Rats; Rats, Sprague-Dawley; Triglycerides | 2006 |
Asymmetric dimethylarginine reduced erythrocyte deformability in streptozotocin-induced diabetic rats.
Topics: Animals; Aorta, Thoracic; Arginine; Diabetes Mellitus, Experimental; Endothelium, Vascular; Erythrocyte Deformability; In Vitro Techniques; Male; Malondialdehyde; Nitric Oxide; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Vitamin E | 2007 |
Effects of in vivo antioxidant enzyme activities of myrtle oil in normoglycaemic and alloxan diabetic rabbits.
Topics: Alloxan; Animals; Antioxidants; Catalase; Diabetes Mellitus, Experimental; Female; Glucose; Homeostasis; Hypoglycemic Agents; Lipid Peroxidation; Liver; Male; Malondialdehyde; Myrtus; Nitrates; Nitrites; Oxidative Stress; Plant Oils; Plants, Medicinal; Rabbits; Superoxide Dismutase | 2007 |
Protective effect of bezafibrate on streptozotocin-induced oxidative stress and toxicity in rats.
Topics: Administration, Oral; Animals; Antioxidants; Bezafibrate; Blood Glucose; Catalase; Diabetes Mellitus, Experimental; Glutathione; Glutathione Peroxidase; Hyperglycemia; Hypolipidemic Agents; Injections, Intraperitoneal; Insulin-Secreting Cells; Islets of Langerhans; Lipid Peroxidation; Liver; Male; Malondialdehyde; Oxidative Stress; Rats; Rats, Wistar; Streptozocin; Superoxide Dismutase; Time Factors | 2007 |
Blockade of the renin-angiotensin system attenuates sarcolemma and sarcoplasmic reticulum remodeling in chronic diabetes.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Diabetes Mellitus, Experimental; Diabetic Angiopathies; Enalapril; Losartan; Male; Malondialdehyde; Rats; Rats, Sprague-Dawley; Renin-Angiotensin System; Sarcolemma; Sarcoplasmic Reticulum; Ventricular Dysfunction, Left; Ventricular Function, Left | 2006 |
Protective effect of Lycium barbarum polysaccharides on streptozotocin-induced oxidative stress in rats.
Topics: Animals; Blood Glucose; Body Weight; Diabetes Mellitus, Experimental; Drugs, Chinese Herbal; Insulin; Kidney; Liver; Malondialdehyde; Oxidative Stress; Rats; Rats, Wistar; Streptozocin; Superoxide Dismutase | 2007 |
Study of potential systemic oxidative stress animal models for the evaluation of antioxidant activity: status of lipid peroxidation and fat-soluble antioxidants.
Topics: alpha-Tocopherol; Animals; Antioxidants; Atherosclerosis; Carbon Tetrachloride; Diabetes Mellitus, Experimental; gamma-Tocopherol; Lipid Peroxidation; Male; Malondialdehyde; Oxidative Stress; Rabbits; Rats; Rats, Sprague-Dawley; Rats, Wistar; Ubiquinone; Vitamin A; Vitamin E Deficiency | 2007 |
Simvastatin pretreatment reduces the severity of limb ischemia in an experimental diabetes model.
Topics: Animals; Diabetes Mellitus, Experimental; Edema; Glutathione; Hindlimb; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Ischemia; Male; Malondialdehyde; Muscle, Skeletal; Necrosis; Peroxidase; Random Allocation; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Severity of Illness Index; Simvastatin; Time Factors; Tourniquets | 2007 |
Central nervous system protection by resveratrol in streptozotocin-induced diabetic rats.
Topics: Animals; Central Nervous System Diseases; Diabetes Mellitus, Experimental; Diabetic Neuropathies; Free Radical Scavengers; Glutathione; Hyperglycemia; Lipid Peroxidation; Male; Malondialdehyde; Medulla Oblongata; Neuroprotective Agents; Nitric Oxide; Oxidative Stress; Rats; Rats, Wistar; Resveratrol; Spinal Cord; Stilbenes; Vasodilator Agents; Xanthine Oxidase | 2007 |
Effect of Momordica grosvenori on oxidative stress pathways in renal mitochondria of normal and alloxan-induced diabetic mice. Involvement of heme oxygenase-1.
Topics: Animals; Diabetes Mellitus, Experimental; Dose-Response Relationship, Drug; Gene Expression Regulation; Glutathione; Heme Oxygenase-1; Kidney; Lipid Peroxidation; Male; Malondialdehyde; Mice; Mice, Inbred BALB C; Mitochondria; Momordica; Oxidative Stress; Phytotherapy; Plant Extracts; Random Allocation; Superoxide Dismutase | 2007 |
Effects of leptin on oxidative stress in healthy and Streptozotocin-induced diabetic rats.
Topics: Animals; Blood Glucose; Diabetes Mellitus, Experimental; Glutathione; Health; Leptin; Male; Malondialdehyde; Oxidative Stress; Rats; Rats, Wistar; Streptozocin; Thiobarbituric Acid Reactive Substances | 2007 |
Protective effects of broccoli (Brassica oleracea) against oxidative damage in vitro and in vivo.
Topics: Animals; Antioxidants; Blood Glucose; Body Weight; Brassica; Diabetes Mellitus, Experimental; Disease Models, Animal; Dose-Response Relationship, Drug; In Vitro Techniques; Kidney; Lipid Peroxidation; Liver; Male; Malondialdehyde; Organ Size; Oxidative Stress; Plant Extracts; Rats; Rats, Wistar; Serum Albumin; Thiobarbituric Acid Reactive Substances; Time Factors | 2006 |
Vanadyl sulfate, taurine, and combined vanadyl sulfate and taurine treatments in diabetic rats: effects on the oxidative and antioxidative systems.
Topics: Animals; Antioxidants; Blood Glucose; Diabetes Mellitus, Experimental; Hypoglycemic Agents; Liver; Male; Malondialdehyde; Muscle, Skeletal; Myocardium; Oxidants; Oxidation-Reduction; Oxidative Stress; Rats; Rats, Wistar; Taurine; Vanadium Compounds | 2007 |
Antiinflammatory and antifibrogenic effects of s-ethyl cysteine and s-methyl cysteine in the kidney of diabetic mice.
Topics: Albuminuria; Animals; Anti-Inflammatory Agents; Antioxidants; Collagen Type IV; Cysteine; Cytokines; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Drinking; Fibrosis; Glutathione; Kidney; Male; Malondialdehyde; Mice; Mice, Inbred BALB C; Weight Loss | 2007 |
Effect of zinc on the lipid peroxidation and the antioxidant defense systems of the alloxan-induced diabetic rabbits.
Topics: Administration, Oral; Alloxan; Animals; Antioxidants; Blood Glucose; Catalase; Ceruloplasmin; Copper; Diabetes Mellitus, Experimental; Glutathione; Glutathione Peroxidase; Iron; Lipid Peroxidation; Malondialdehyde; Oxidoreductases; Rabbits; Superoxide Dismutase; Zinc; Zinc Sulfate | 2007 |
Two diallyl sulphides derived from garlic inhibit meticillin-resistant Staphylococcus aureus infection in diabetic mice.
Topics: Allyl Compounds; Animals; Anti-Bacterial Agents; Antithrombin III; C-Reactive Protein; Colony Count, Microbial; Cytokines; Diabetes Mellitus, Experimental; Disease Models, Animal; Disulfides; Fibrinogen; Fibronectins; Garlic; Humans; Kidney; Male; Malondialdehyde; Methicillin Resistance; Mice; Mice, Inbred BALB C; Microbial Viability; Plasminogen Activator Inhibitor 1; Protein C; Spleen; Staphylococcal Infections; Staphylococcus aureus; Streptozocin; Sulfides | 2007 |
Protective effect of ursodeoxycholic acid on liver mitochondrial function in rats with alloxan-induced diabetes: link with oxidative stress.
Topics: Alloxan; Animals; Diabetes Mellitus, Experimental; Liver; Luminescent Measurements; Male; Malondialdehyde; Mitochondria; NADH Dehydrogenase; Oxidative Stress; Oxygen Consumption; Rats; Rats, Wistar; Succinate Dehydrogenase; Ursodeoxycholic Acid | 2007 |
Effects of stobadine and vitamin E in diabetes-induced retinal abnormalities: involvement of oxidative stress.
Topics: Aldehyde Reductase; Animals; Antioxidants; Blood Glucose; Carbolines; Diabetes Mellitus, Experimental; Diabetic Retinopathy; Endothelial Growth Factors; Immunohistochemistry; Male; Malondialdehyde; Oxidative Stress; Rats; Rats, Wistar; Retina; Vitamin E | 2007 |
Prevention of early liver injury by breviscapine in streptozotocin-induced diabetic rats.
Topics: Animals; Antioxidants; Diabetes Complications; Diabetes Mellitus, Experimental; Drugs, Chinese Herbal; Erigeron; Flavonoids; Lipid Metabolism; Lipid Peroxidation; Liver Diseases; Male; Malondialdehyde; Plants, Medicinal; Rats; Rats, Sprague-Dawley | 2007 |
[Protective effect of shenfu injection against ischemia-reperfusion injury due to pancreas transplantation in rats].
Topics: Animals; Cell Aggregation; Diabetes Mellitus, Experimental; Drugs, Chinese Herbal; Injections; Malondialdehyde; Nitric Oxide; Pancreas; Pancreas Transplantation; Protective Agents; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Superoxide Dismutase; Tumor Necrosis Factor-alpha | 2006 |
A study of antidiabetic and antioxidant effects of Helichrysum graveolens capitulums in streptozotocin-induced diabetic rats.
Topics: Animals; Antioxidants; Blood Glucose; Diabetes Mellitus, Experimental; Flavonoids; Glutathione; Helichrysum; Hypoglycemic Agents; Kidney; Liver; Male; Malondialdehyde; Myocardium; Phenols; Phytotherapy; Plant Extracts; Polyphenols; Rats; Rats, Wistar | 2007 |
Exercise training is associated with improved levels of C-reactive protein and adiponectin in ZDF (type 2) diabetic rats.
Topics: Adiponectin; Animals; Animals, Genetically Modified; C-Reactive Protein; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Inflammation; Male; Malondialdehyde; Physical Conditioning, Animal; Rats; Rats, Zucker; Superoxide Dismutase; Swimming; Time Factors | 2007 |
Protective effects of chronic melatonin treatment against renal ischemia/reperfusion injury in streptozotocin-induced diabetic rats.
Topics: Animals; Antioxidants; Diabetes Mellitus, Experimental; Kidney Diseases; Lipid Peroxidation; Male; Malondialdehyde; Melatonin; Nitric Oxide; Rats; Rats, Sprague-Dawley; Reperfusion Injury | 2007 |
Antihyperglycemic activity of kinsenoside, a high yielding constituent from Anoectochilus roxburghii in streptozotocin diabetic rats.
Topics: 4-Butyrolactone; Animals; Blood Glucose; China; Diabetes Mellitus, Experimental; Female; Free Radical Scavengers; Glucose Tolerance Test; Hypoglycemic Agents; Insulin-Secreting Cells; Male; Malondialdehyde; Mice; Monosaccharides; Nitric Oxide; Nitric Oxide Synthase; Orchidaceae; Pancreas; Phytotherapy; Rats; Rats, Wistar; Superoxide Dismutase | 2007 |
The effect of vaginal candidiasis on the levels of the oxidative biomarkers in plasma and tissue samples of diabetic rats.
Topics: Animals; Ascorbic Acid; Biomarkers; Blood Glucose; Candidiasis; Diabetes Mellitus, Experimental; Disease Models, Animal; Female; Glutathione; Lipid Peroxides; Malondialdehyde; Oxidative Stress; Random Allocation; Rats; Rats, Wistar; Streptozocin; Vaginal Diseases | 2007 |
Curcumin prevents streptozotocin-induced islet damage by scavenging free radicals: a prophylactic and protective role.
Topics: Animals; Antibiotics, Antineoplastic; Cells, Cultured; Curcumin; Diabetes Mellitus, Experimental; DNA Fragmentation; Dose-Response Relationship, Drug; Free Radical Scavengers; In Vitro Techniques; Insulin; Insulin Secretion; Islets of Langerhans; Male; Malondialdehyde; Mice; Mice, Inbred C57BL; Nitric Oxide; Poly(ADP-ribose) Polymerases; Reactive Oxygen Species; Streptozocin; Superoxide Dismutase | 2007 |
Beneficial effect of heme oxygenase-1 expression on myocardial ischemia-reperfusion involves an increase in adiponectin in mildly diabetic rats.
Topics: Adiponectin; Animals; bcl-X Protein; Cardiovascular Agents; Coronary Vessels; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Enzyme Induction; Heme Oxygenase (Decyclizing); Lactic Acid; Male; Malondialdehyde; Microcirculation; Myocardial Reperfusion Injury; Myocardium; Niacinamide; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Phosphorylation; Proto-Oncogene Proteins c-akt; Protoporphyrins; Rats; Rats, Wistar; Severity of Illness Index; Streptozocin; Superoxides; Time Factors; Up-Regulation; Vascular Resistance; Vasoconstriction | 2007 |
Beneficial effects of spironolactone on glomerular injury in streptozotocin-induced diabetic rats.
Topics: Animals; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Fibronectins; Glutathione Peroxidase; Hypertrophy; Kidney Cortex; Kidney Glomerulus; Male; Malondialdehyde; Mineralocorticoid Receptor Antagonists; Oxidative Stress; Plasminogen Activator Inhibitor 1; Rats; Rats, Sprague-Dawley; RNA, Messenger; Spironolactone; Superoxide Dismutase; Transforming Growth Factor beta1 | 2007 |
Pretreatment effect of resveratrol on streptozotocin-induced diabetes in rats.
Topics: Animals; Antioxidants; Catalase; Copper; Diabetes Mellitus, Experimental; Male; Malondialdehyde; Nitrates; Nitric Oxide; Nitrites; Rats; Rats, Sprague-Dawley; Resveratrol; Stilbenes; Streptozocin; Zinc | 2007 |
Resveratrol: is there any effect on healthy subject?
Topics: Animals; Antioxidants; Catalase; Copper; Diabetes Mellitus, Experimental; Humans; Male; Malondialdehyde; Nitric Oxide; Nitrogen; Oxygen; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Resveratrol; Stilbenes; Zinc | 2007 |
The effects of vitamin E on lipid peroxidation, nitric oxide production and superoxide dismutase expression in hyperglycemic rats with cerebral ischemia-reperfusion injury.
Topics: Animals; Antioxidants; Blood Pressure; Brain Diseases; Diabetes Mellitus, Experimental; Hyperglycemia; Lipid Peroxidation; Male; Malondialdehyde; Nitrates; Nitric Oxide; Nitrites; Rats; Rats, Wistar; Reperfusion Injury; Superoxide Dismutase; Vitamin E | 2007 |
[Protection of polysaccharides-2b from mudan cortex of Paeonia suffruticosa andr on diabetic cataract in rats].
Topics: Animals; Catalase; Cataract; Diabetes Mellitus, Experimental; Glutathione Peroxidase; Lens, Crystalline; Male; Malondialdehyde; Paeonia; Phytotherapy; Plant Bark; Plants, Medicinal; Polysaccharides; Random Allocation; Rats; Rats, Sprague-Dawley; Sodium-Potassium-Exchanging ATPase; Streptozocin; Superoxide Dismutase | 2007 |
Antioxidant and pancreas-protective effect of aucubin on rats with streptozotocin-induced diabetes.
Topics: Animals; Antioxidants; Blood Glucose; Catalase; Diabetes Mellitus, Experimental; Glucosides; Glutathione Peroxidase; Immunohistochemistry; Insulin-Secreting Cells; Iridoid Glucosides; Iridoids; Lipid Peroxidation; Male; Malondialdehyde; Pancreas; Protective Agents; Rats; Rats, Wistar; Streptozocin; Superoxide Dismutase | 2008 |
The effects of rosiglitazone on oxidative stress and lipid profile in left ventricular muscles of diabetic rats.
Topics: Animals; Blood Glucose; Body Weight; Diabetes Mellitus, Experimental; Glycated Hemoglobin; Heart Ventricles; Lipid Metabolism; Male; Malondialdehyde; Oxidative Stress; Rats; Rats, Wistar; Rosiglitazone; Streptozocin; Thiazolidinediones; Tyrosine | 2008 |
Action of pelargonidin on hyperglycemia and oxidative damage in diabetic rats: implication for glycation-induced hemoglobin modification.
Topics: Animals; Anthocyanins; Antioxidants; Diabetes Mellitus, Experimental; DNA; Fructosamine; Glucose; Glucose Tolerance Test; Hemoglobins; Hyperglycemia; Insulin; Iron; Liver; Male; Malondialdehyde; Oxidative Stress; Protein Carbonylation; Rats; Rats, Wistar; Superoxide Dismutase | 2008 |
In vivo evaluation of anti-oxidant and anti-lipidimic potential of Annona squamosa aqueous extract in Type 2 diabetic models.
Topics: Animals; Annona; Antioxidants; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Glutathione; Lipids; Malondialdehyde; Oxidative Stress; Plant Extracts; Plant Leaves; Rats; Rats, Wistar; Streptozocin; Superoxide Dismutase | 2008 |
Chronic administration of genistein improves aortic reactivity of streptozotocin-diabetic rats: mode of action.
Topics: Acetylcholine; Animals; Aorta, Thoracic; Diabetes Mellitus, Experimental; Dose-Response Relationship, Drug; Enzyme Inhibitors; Genistein; Male; Malondialdehyde; Muscle, Smooth, Vascular; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase Type III; Phytoestrogens; Rats; Rats, Wistar; Superoxide Dismutase; Thiobarbituric Acid Reactive Substances | 2008 |
Effects of folic acid on cardiac myocyte apoptosis in rats with streptozotocin-induced diabetes mellitus.
Topics: Animals; Apoptosis; bcl-2-Associated X Protein; Blood Glucose; Diabetes Complications; Diabetes Mellitus, Experimental; Dietary Supplements; Dose-Response Relationship, Drug; fas Receptor; Folic Acid; Insulin; Male; Malondialdehyde; Myocytes, Cardiac; Nitric Oxide; Oxidative Stress; Proto-Oncogene Proteins c-bcl-2; Rats; Rats, Wistar; Superoxide Dismutase | 2008 |
Ability of alpha-lipoic acid to reverse the diabetic cystopathy in a rat model.
Topics: Animals; Antioxidants; Catalase; Diabetes Complications; Diabetes Mellitus, Experimental; Male; Malondialdehyde; Nerve Growth Factor; Rats; Rats, Sprague-Dawley; Superoxide Dismutase; Thioctic Acid; Urinary Bladder; Urinary Bladder Diseases | 2008 |
An imbalance in arachidonic acid metabolism in diabetes.
Topics: Animals; Aorta; Arachidonic Acids; Blood Platelets; Diabetes Mellitus; Diabetes Mellitus, Experimental; Epoprostenol; Humans; Kidney Cortex; Male; Malondialdehyde; Prostaglandin-Endoperoxide Synthases; Rats; Thromboxane-A Synthase | 1980 |
[Effect of an extract from the roots of bryony (Bryonia alba) on lipid peroxidation in the liver of rats with alloxan diabetes].
Topics: Alloxan; Animals; Diabetes Mellitus, Experimental; Fatty Acids; Hypoglycemic Agents; Lipid Peroxides; Liver; Malondialdehyde; Microsomes, Liver; Phospholipids; Plant Extracts; Rats | 1981 |
Effect of intake of exogenous vitamins C, E and beta-carotene on the antioxidative status in kidneys of rats with streptozotocin-induced diabetes.
Topics: Animals; Antioxidants; Ascorbic Acid; beta Carotene; Body Weight; Carotenoids; Diabetes Mellitus, Experimental; Glutathione; Kidney; Male; Malondialdehyde; Organ Size; Rats; Rats, Wistar; Vitamin E | 1995 |
[Effect of serum glucose on the function of pancreatic exocrine in diabetic rats].
Topics: Amylases; Animals; Blood Glucose; Cells, Cultured; Diabetes Mellitus, Experimental; Male; Malondialdehyde; Pancreas; Rats; Rats, Wistar; Sincalide; Vanadates | 1994 |
The antioxidative potential of cerebral microvessels in experimental diabetes mellitus.
Topics: Amidines; Animals; Antioxidants; Diabetes Mellitus, Experimental; Free Radicals; Insulin; Lipid Peroxidation; Male; Malondialdehyde; Microcirculation; Phycoerythrin; Prosencephalon; Rats; Rats, Inbred F344 | 1995 |
Free radical damage in acute nerve compression.
Topics: Animals; Antioxidants; Deferoxamine; Diabetes Mellitus, Experimental; Diabetic Neuropathies; Female; Free Radicals; Lipid Peroxidation; Malondialdehyde; Nerve Compression Syndromes; Pregnatrienes; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Sciatic Nerve | 1995 |
The relative roles of advanced glycation, oxidation and aldose reductase inhibition in the development of experimental diabetic nephropathy in the Sprague-Dawley rat.
Topics: Albuminuria; Aldehyde Reductase; Animals; Antioxidants; Blood Glucose; Body Weight; Butylated Hydroxytoluene; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Glycated Hemoglobin; Glycosylation; Guanidines; Kidney Cortex; Male; Malondialdehyde; Oxidation-Reduction; Phthalazines; Probucol; Rats; Rats, Sprague-Dawley; Sorbitol | 1995 |
The effects of desferrioxamine and ascorbate on oxidative stress in the streptozotocin diabetic rat.
Topics: Animals; Ascorbic Acid; Blood Glucose; Cholesterol; Copper; Deferoxamine; Diabetes Mellitus, Experimental; Erythrocyte Membrane; Glycated Hemoglobin; Glycated Serum Albumin; Glycation End Products, Advanced; Humans; Insulin; Insulin, Regular, Pork; Iron; Liver; Male; Malondialdehyde; Oxidative Stress; Rats; Rats, Wistar; Recombinant Proteins; Reference Values; Serum Albumin; Triglycerides; Vitamin A; Vitamin E | 1995 |
The pyrimido-pyrimidine derivatives, dipyridamole and RA-642, reduce opacification of crystalline lens in diabetic rats.
Topics: Animals; Blood Glucose; Cardiotonic Agents; Cataract; Diabetes Mellitus, Experimental; Dipyridamole; Lens, Crystalline; Lipid Peroxidation; Male; Malondialdehyde; Mopidamol; Pyrimidines; Rats; Rats, Wistar; Superoxides | 1994 |
Tissue-specific distribution of malondialdehyde modified proteins in diabetes mellitus.
Topics: Animals; Blood Proteins; Blotting, Western; Diabetes Mellitus, Experimental; Insulin; Liver; Lung; Male; Malondialdehyde; Molecular Weight; Proteins; Rats; Rats, Inbred F344; Tissue Distribution | 1994 |
In vitro effect of D-myo-inositol 1,2,6-trisphosphate (PP-56) on aggregation of platelets from normal and diabetic rats: relationship to malondialdehyde release and phosphoinositide pathway.
Topics: Animals; Chelating Agents; Diabetes Mellitus, Experimental; Erythrocytes; In Vitro Techniques; Inositol; Inositol Phosphates; Male; Malondialdehyde; Phosphatidylinositols; Platelet Aggregation; Platelet Aggregation Inhibitors; Rats; Rats, Sprague-Dawley | 1994 |
Changes of lipid peroxidation parameters in dogs with alloxan diabetes.
Topics: Alanine Transaminase; Animals; Blood Glucose; Catalase; Diabetes Mellitus, Experimental; Dogs; Female; Glutathione Peroxidase; Lipid Peroxidation; Male; Malondialdehyde; Superoxide Dismutase | 1993 |
Diabetes-related changes in the protein composition of rat cerebral microvessels.
Topics: Animals; Brain; Densitometry; Diabetes Mellitus, Experimental; Diabetic Angiopathies; Electrophoresis, Gel, Two-Dimensional; Glycosylation; Male; Malondialdehyde; Microcirculation; Protein Processing, Post-Translational; Proteins; Rats; Rats, Inbred F344 | 1994 |
Lipid peroxide and glutathione levels in the liver and its subcellular fractions of alloxan diabetic rats.
Topics: Animals; Diabetes Mellitus, Experimental; Glutathione; Lipid Peroxides; Liver; Male; Malondialdehyde; Microsomes, Liver; Mitochondria, Liver; Rats; Rats, Wistar; Subcellular Fractions | 1993 |
Effect of diabetes on levels of lipid peroxides and glycolipids in rat brain.
Topics: Alloxan; Animals; Body Weight; Brain; Catalase; Diabetes Mellitus, Experimental; Fatty Acids, Nonesterified; Glycolipids; Insulin; Lipid Peroxides; Male; Malondialdehyde; Rats; Rats, Sprague-Dawley; Superoxide Dismutase | 1993 |
Antioxidative state of the myocardium and kidneys in acute diabetic rats.
Topics: Acute Disease; Animals; Antioxidants; Catalase; Diabetes Mellitus, Experimental; Glutathione; Glutathione Peroxidase; Glutathione Transferase; Insulin; Kidney; Male; Malondialdehyde; Myocardium; Oxidation-Reduction; Rats; Rats, Wistar; Superoxide Dismutase | 1993 |
Effects of diabetes on lipid peroxidation and scavenger activity in ischemia/reperfusion injury.
Topics: Animals; Diabetes Mellitus, Experimental; Electrocardiography; Free Radical Scavengers; Hemodynamics; Lipid Peroxidation; Male; Malondialdehyde; Myocardial Reperfusion Injury; Myocardium; Rats; Rats, Wistar; Superoxide Dismutase; Time Factors | 1993 |
[Clinical and experimental study on effect of jin-qi-jiang-tang-pian on qi-yin deficiency and hyperactivity of diabetes mellitus].
Topics: Aged; Animals; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Drugs, Chinese Herbal; Female; Humans; Hypoglycemic Agents; Male; Malondialdehyde; Mice; Middle Aged; Rats; Rats, Wistar; Superoxide Dismutase; Tablets | 1993 |
Mechanism of decreased arachidonic acid in the renal cortex of rats with diabetes mellitus.
Topics: Acyl-CoA Dehydrogenase, Long-Chain; Acyl-CoA Oxidase; Animals; Arachidonic Acid; Delta-5 Fatty Acid Desaturase; Diabetes Mellitus, Experimental; Dinoprostone; Esterification; Fatty Acid Desaturases; Kidney Cortex; Linoleoyl-CoA Desaturase; Liver; Male; Malondialdehyde; Myocardium; Oxidoreductases; Rats; Rats, Sprague-Dawley | 1993 |
Diabetes increases excretion of urinary malonaldehyde conjugates in rats.
Topics: Animals; Diabetes Mellitus, Experimental; Lipid Peroxidation; Male; Malondialdehyde; Rats; Rats, Wistar; Thiobarbituric Acid Reactive Substances | 1993 |
Malondialdehyde modified proteins and their antibodies in the plasma of control and streptozotocin induced diabetic rats.
Topics: Animals; Antibodies; Antibody Specificity; Antigen-Antibody Complex; Blood Proteins; Blotting, Western; Diabetes Mellitus, Experimental; Electrophoresis, Polyacrylamide Gel; Enzyme-Linked Immunosorbent Assay; Immunoglobulin G; Male; Malondialdehyde; Rats; Rats, Inbred F344 | 1993 |
The vitamin-E derivative U-83836-E in the low-dose streptozocin- treated mouse: effects on diabetes development.
Topics: Animals; Antioxidants; Blood Glucose; Chromans; Cohort Studies; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Free Radical Scavengers; Islets of Langerhans; Kidney; Lipid Peroxidation; Liver; Male; Malondialdehyde; Mice; Mice, Inbred C57BL; Piperazines; Superoxide Dismutase; Time Factors | 1995 |
Effects of insulin treatment on endoneurial and systemic oxidative stress in relation to nerve conduction in streptozotocin-diabetic rats.
Topics: Animals; Antioxidants; Catalase; Diabetes Mellitus, Experimental; Glutathione; Insulin; Lipid Peroxidation; Male; Malondialdehyde; Neural Conduction; Oxidative Stress; Peripheral Nerves; Rats; Rats, Wistar; Superoxide Dismutase; Time Factors | 1996 |
Nerve function and oxidative stress in diabetic and vitamin E-deficient rats.
Topics: Animals; Antioxidants; Diabetes Mellitus, Experimental; Diabetic Neuropathies; Hydrogen Peroxide; Male; Malondialdehyde; Microcirculation; Neural Conduction; Oxidative Stress; Peripheral Nerves; Rats; Rats, Wistar; Reactive Oxygen Species; Sciatic Nerve; Vitamin E Deficiency | 1998 |
Glycoxidation in aortic collagen from STZ-induced diabetic rats and its relevance to vascular damage.
Topics: Aldehydes; Animals; Aorta; Collagen; Diabetes Mellitus, Experimental; Diabetic Angiopathies; Enzyme-Linked Immunosorbent Assay; Glycation End Products, Advanced; Glycosylation; Immunohistochemistry; Lipid Peroxidation; Lysine; Male; Malondialdehyde; Oxidation-Reduction; Rats; Rats, Sprague-Dawley; Streptozocin | 1998 |
Effect of taurine supplementation on the lipid peroxide formation and the activities of glutathione-related enzymes in the liver and islet of type I and II diabetic model mice.
Topics: Animals; Blood Glucose; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Glutathione; Glutathione Peroxidase; Glutathione Transferase; Islets of Langerhans; Lipid Peroxides; Liver; Malondialdehyde; Mice; Mice, Inbred ICR; Taurine | 1998 |
Prevention of alloxan-induced diabetes mellitus in the rat by silymarin.
Topics: Alloxan; Animals; Blood Glucose; Diabetes Mellitus, Experimental; Free Radical Scavengers; Glutathione; Kinetics; Lipid Peroxidation; Liver; Male; Malondialdehyde; Pancreas; Rats; Rats, Wistar; Silymarin | 1998 |
Effect of angiotensin convertase inhibitors on lipid peroxidation and peroxyl radical-trapping capacity in rats with experimental diabetes.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Captopril; Diabetes Mellitus, Experimental; Enalapril; Erythrocytes; Free Radicals; Lipid Peroxidation; Male; Malondialdehyde; Peroxides; Rats; Rats, Wistar | 1998 |
Oxidative stress in diabetic rats induced by streptozotocin: protective effects of melatonin.
Topics: Animals; Blood Glucose; Cholesterol; Cholesterol, HDL; Diabetes Mellitus, Experimental; Female; Fructosamine; Glutathione; Glycated Hemoglobin; Glycosuria; Lipid Peroxides; Malondialdehyde; Melatonin; Oxidative Stress; Rats; Rats, Wistar; Streptozocin; Triglycerides | 1998 |
Effect of aminoguanidine on lipid peroxidation and activities of antioxidant enzymes in the diabetic kidney.
Topics: Albuminuria; Animals; Blood Glucose; Body Weight; Catalase; Diabetes Mellitus, Experimental; Glycated Hemoglobin; Guanidines; Kidney; Lipid Peroxidation; Male; Malondialdehyde; Organ Size; Rats; Rats, Wistar; Superoxide Dismutase | 1998 |
Oxidative stress measurement by in vivo electron spin resonance spectroscopy in rats with streptozotocin-induced diabetes.
Topics: Animals; Antioxidants; Blood Glucose; Cyclic N-Oxides; Diabetes Mellitus, Experimental; Electron Spin Resonance Spectroscopy; Female; Insulin, Isophane; Kinetics; Malondialdehyde; Oxidative Stress; Pyrrolidines; Radiation-Protective Agents; Rats; Rats, Wistar; Time Factors; Vitamin E | 1998 |
Effect of aminoguanidine on erythrocyte lipid peroxidation and activities of antioxidant enzymes in experimental diabetes.
Topics: Animals; Blood Glucose; Body Weight; Catalase; Diabetes Mellitus, Experimental; Erythrocytes; Glutathione Peroxidase; Glycated Hemoglobin; Guanidines; Lipid Peroxidation; Malondialdehyde; Rats; Rats, Wistar; Streptozocin; Superoxide Dismutase | 1998 |
Contributions of polyol pathway to oxidative stress in diabetic cataract.
Topics: Aldehyde Reductase; Animals; Antioxidants; Ascorbic Acid; Buthionine Sulfoximine; Cataract; Culture Media; Diabetes Mellitus, Experimental; Enzyme Inhibitors; Gene Expression; Glutathione; Glyceraldehyde; L-Iditol 2-Dehydrogenase; Lens, Crystalline; Malondialdehyde; Mice; Mice, Transgenic; Organ Culture Techniques; Oxidative Stress; Polymers; Vitamin E | 1999 |
The influence of NO synthase inhibitor and free oxygen radicals scavenger--methylene blue--on streptozotocin-induced diabetes in rats.
Topics: Animals; Antioxidants; Blood Glucose; Diabetes Mellitus, Experimental; Enzyme Inhibitors; Free Radical Scavengers; Glycated Hemoglobin; Male; Malondialdehyde; Methylene Blue; Nitric Oxide Synthase; Oxidative Stress; Rats; Rats, Wistar; Superoxide Dismutase; Weight Loss | 1998 |
Effect of dietary taurine supplementation on GSH and NAD(P)-redox status, lipid peroxidation, and energy metabolism in diabetic precataractous lens.
Topics: Adenosine Triphosphate; Animals; Cataract; Chromatography, High Pressure Liquid; Diabetes Mellitus, Experimental; Dietary Supplements; Energy Metabolism; Glutathione; Hexoses; Lens, Crystalline; Lipid Peroxidation; Male; Malondialdehyde; NADP; Oxidation-Reduction; Rats; Rats, Sprague-Dawley; Sugar Alcohols; Taurine | 1999 |
Protective effects of Gingko biloba extract EGb 761 on myocardium of experimentally diabetic rats. I: ultrastructural and biochemical investigation on cardiomyocytes.
Topics: Animals; Cardiomyopathies; Creatine Kinase; Diabetes Mellitus, Experimental; Flavonoids; Free Radical Scavengers; Gene Expression Regulation, Enzymologic; Ginkgo biloba; Malondialdehyde; Microscopy, Electron; Myocardium; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Plant Extracts; Rats; Rats, Wistar; Reverse Transcriptase Polymerase Chain Reaction; RNA; Superoxide Dismutase | 1999 |
Alternations in free radical erythrocyte-defense mechanisms in streptozotocin induced diabetic rats - effect of antioxidant treatment.
Topics: Allopurinol; Animals; Antioxidants; Catalase; Chromans; Diabetes Mellitus, Experimental; Erythrocytes; Free Radical Scavengers; Glutathione; Glutathione Disulfide; Glutathione Peroxidase; Male; Malondialdehyde; Rats; Rats, Wistar; Superoxide Dismutase | 1999 |
Effect of streptozotocin on glutathione and lipid peroxide levels in various tissues of rats.
Topics: Animals; Diabetes Mellitus, Experimental; Glutathione; Islets of Langerhans; Kidney; Lipid Peroxidation; Lipid Peroxides; Male; Malondialdehyde; Mitochondria; Mitochondria, Liver; Necrosis; Pancreas; Rats; Rats, Wistar; Streptozocin | 1998 |
Effect of vitamin E and allylamine on the proliferation of cultured aortic smooth muscle cells from streptozotocin-induced diabetic rats.
Topics: Allylamine; Animals; Antioxidants; Cell Division; Cells, Cultured; Diabetes Mellitus, Experimental; Diabetic Angiopathies; DNA; Free Radical Scavengers; Male; Malondialdehyde; Muscle, Smooth, Vascular; Rats; Rats, Wistar; Thymidine; Vitamin E | 1999 |
Antioxidant status in experimental type 2 diabetes mellitus: effects of glibenclamide and glipizide on various rat tissues.
Topics: Animals; Antioxidants; Brain; Catalase; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Glipizide; Glyburide; Hypoglycemic Agents; Kidney; Liver; Lung; Male; Malondialdehyde; Myocardium; Rats | 1999 |
Simultaneous determination of formaldehyde and methylglyoxal in urine: involvement of semicarbazide-sensitive amine oxidase-mediated deamination in diabetic complications.
Topics: Amine Oxidase (Copper-Containing); Animals; Chromatography, High Pressure Liquid; Diabetes Mellitus, Experimental; Enzyme Inhibitors; Formaldehyde; Male; Malondialdehyde; Methylamines; Phenylhydrazines; Pyruvaldehyde; Rats; Rats, Wistar; Semicarbazides; Sensitivity and Specificity | 1999 |
Effect of angiotensin convertase inhibitors and AT1 angiotensin receptor antagonists on the development of oxidative stress in the kidney of diabetic rats.
Topics: Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Body Weight; Catalase; Diabetes Mellitus, Experimental; Glutathione Peroxidase; Kidney; Lipid Peroxidation; Losartan; Male; Malondialdehyde; Organ Size; Oxidative Stress; Rats; Rats, Wistar; Streptozocin; Superoxide Dismutase | 1999 |
Evaluation of a sorbitol dehydrogenase inhibitor on diabetic peripheral nerve metabolism: a prevention study.
Topics: Animals; Diabetes Mellitus, Experimental; Diabetic Neuropathies; Drug Evaluation, Preclinical; Enzyme Inhibitors; Fructose; Glutathione; L-Iditol 2-Dehydrogenase; Male; Malondialdehyde; Mitochondria; NAD; Oxidative Stress; Peripheral Nerves; Rats; Rats, Wistar; Sciatic Nerve; Spectrometry, Fluorescence | 1999 |
Protective role of intraperitoneally administered vitamins C and E and selenium on the levels of lipid peroxidation in the lens of rats made diabetic with streptozotocin.
Topics: Animals; Ascorbic Acid; Diabetes Mellitus, Experimental; Glutathione Peroxidase; Humans; Lens, Crystalline; Lipid Peroxidation; Male; Malondialdehyde; Rats; Rats, Wistar; Selenium; Streptozocin; Vitamin E | 1999 |
Reversal effects of L-arginine treatment on blood pressure and vascular responsiveness of streptozotocin-diabetic rats.
Topics: Animals; Arginine; Blood Glucose; Blood Pressure; Blood Vessels; Body Weight; Diabetes Mellitus, Experimental; Endothelium, Vascular; In Vitro Techniques; Lipid Peroxidation; Male; Malondialdehyde; Muscle Contraction; Muscle Relaxation; Muscle, Smooth, Vascular; Oxidative Stress; Rats; Rats, Wistar; Time Factors; Vasoconstrictor Agents; Vasodilator Agents | 2000 |
Antioxidant therapy and streptozotocin-induced diabetes in pregnant rats.
Topics: Animals; Animals, Newborn; Antioxidants; Blood Glucose; Body Weight; Diabetes Mellitus, Experimental; Female; Glutathione; Glutathione Peroxidase; Malondialdehyde; Oxidative Stress; Pregnancy; Pregnancy in Diabetics; Rats; Rats, Wistar; Superoxide Dismutase; Vitamin E | 1999 |
Protective effect of secoisolariciresinol diglucoside against streptozotocin-induced diabetes and its mechanism.
Topics: Animals; Antioxidants; Blood Glucose; Butylene Glycols; Diabetes Mellitus, Experimental; Glucose; Glucosides; Leukocytes; Lipid Peroxidation; Luminescent Measurements; Male; Malondialdehyde; Oxidative Stress; Pancreas; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Thiobarbituric Acid Reactive Substances | 2000 |
Testis glutathione peroxidase and phospholipid hydroperoxide glutathione peroxidase activities in aminoguanidine-treated diabetic rats.
Topics: Animals; Blood Glucose; Body Weight; Diabetes Mellitus, Experimental; Glutathione Peroxidase; Glycation End Products, Advanced; Guanidines; Male; Malondialdehyde; Nitric Oxide Synthase; Organ Size; Oxidative Stress; Phospholipid Hydroperoxide Glutathione Peroxidase; Rats; Rats, Wistar; Reactive Oxygen Species; Selenium; Sulfhydryl Compounds; Testis | 2000 |
Evaluation of alpha(1)-adrenoceptor antagonist on diabetes-induced changes in peripheral nerve function, metabolism, and antioxidative defense.
Topics: Adrenergic alpha-Antagonists; Animals; Antioxidants; Blood Glucose; Blood Pressure; Body Weight; Creatine; Diabetes Mellitus, Experimental; Glutathione; Hexoses; Inositol; Male; Malondialdehyde; Mitochondria; NAD; Oxidative Stress; Prazosin; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-1; Regional Blood Flow; Sciatic Nerve; Sodium-Potassium-Exchanging ATPase; Sorbitol; Taurine | 2000 |
Lipid peroxidation and activities of antioxidant enzymes in the diabetic kidney: effect of treatment with angiotensin convertase inhibitors.
Topics: Albuminuria; Animals; Antioxidants; Blood Glucose; Captopril; Catalase; Diabetes Mellitus, Experimental; Enalapril; Hemoglobin A; Kidney; Lipid Peroxidation; Male; Malondialdehyde; Organ Size; Peptidyl-Dipeptidase A; Rats; Rats, Wistar; Superoxide Dismutase; Time Factors | 2000 |
Effect of dietary vitamin E supplementation on vascular reactivity of thoracic aorta in streptozotocin-diabetic rats.
Topics: Acetylcholine; Animals; Aorta, Thoracic; Blood Glucose; Body Weight; Calcimycin; Diabetes Mellitus, Experimental; Dietary Supplements; Dose-Response Relationship, Drug; In Vitro Techniques; Liver; Lung; Male; Malondialdehyde; Nitroprusside; Phenylephrine; Potassium Chloride; Rats; Serotonin; Vasoconstriction; Vasoconstrictor Agents; Vasodilation; Vasodilator Agents; Vitamin E | 2001 |
The effect of bradykinin on the oxidative state of rats with acute hyperglycaemia.
Topics: Animals; Blood Glucose; Bradykinin; Catalase; Diabetes Mellitus, Experimental; Glutathione Peroxidase; Hydrogen Peroxide; Hyperglycemia; Insulin; Kinetics; Male; Malondialdehyde; Oxidation-Reduction; Rats; Rats, Wistar; Reference Values; Streptozocin; Superoxide Dismutase | 2001 |
Increase in circulating products of lipid peroxidation (malonaldehyed) in streptozocin induced diabetic mice.
Topics: Animals; Diabetes Mellitus, Experimental; Lipid Peroxidation; Malondialdehyde; Mice; Streptozocin; Thiobarbituric Acid Reactive Substances; Vitamin E | 2000 |
Diabetes-induced biochemical changes in rat lens: attenuation of cataractogenesis by pyruvate.
Topics: Adenosine Triphosphate; Animals; Body Weight; Cataract; Crystallins; Diabetes Mellitus, Experimental; Fructose; Glucose; Glutathione; Glycated Hemoglobin; Lens, Crystalline; Malondialdehyde; Pyruvic Acid; Rats; Sorbitol; Streptozocin; Time Factors | 2000 |
Hypotriglyceridemic and hypocholesterolemic effects of anti-diabetic Momordica charantia (karela) fruit extract in streptozotocin-induced diabetic rats.
Topics: Animals; Anticholesteremic Agents; Asia; Brain; Cholesterol; Cholesterol, HDL; Cucurbitaceae; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Hypoglycemic Agents; Hypolipidemic Agents; Kidney; Latin America; Lipid Peroxidation; Liver; Male; Malondialdehyde; Phospholipids; Phytotherapy; Plant Extracts; Rats; Rats, Wistar; Reference Values; Testis; Thiobarbituric Acid Reactive Substances; Triglycerides | 2001 |
Raxofelast, a hydrophilic vitamin E-like antioxidant, stimulates wound healing in genetically diabetic mice.
Topics: Animals; Antioxidants; Benzofurans; Diabetes Mellitus, Experimental; Female; Hydroxyproline; Malondialdehyde; Mice; Mice, Inbred C57BL; Mice, Mutant Strains; Peroxidase; Skin; Vitamin E; Wound Healing | 2001 |
Streptozotocin-induced diabetes decreases rat sarcolemmal lactate transport.
Topics: Animals; Blood Glucose; Body Weight; Diabetes Mellitus, Experimental; Down-Regulation; Glutathione Peroxidase; Hindlimb; In Vitro Techniques; Insulin; Lactic Acid; Lipid Peroxidation; Male; Malondialdehyde; Muscle, Skeletal; Osmolar Concentration; Oxidative Stress; Rats; Rats, Wistar; Sarcolemma | 2001 |
Lipid peroxidation and scavenging enzyme activity in streptozotocin-induced diabetes.
Topics: Animals; Animals, Newborn; Blood Glucose; Body Weight; Diabetes Mellitus, Experimental; Female; Glutathione; Glutathione Peroxidase; Lipid Peroxidation; Liver; Lung; Malondialdehyde; Pregnancy; Pregnancy in Diabetics; Prenatal Exposure Delayed Effects; Rats; Rats, Wistar; Reference Values; Superoxide Dismutase; Vitamin E; Vitamin E Deficiency | 2000 |
Melatonin inhibits lipid peroxidation and stimulates the antioxidant status of diabetic rats.
Topics: Animals; Antioxidants; Blood Glucose; Diabetes Mellitus, Experimental; Erythrocyte Membrane; Female; Free Radical Scavengers; Glutathione; Glutathione Peroxidase; Lipid Peroxidation; Lipid Peroxides; Malondialdehyde; Melatonin; Rats; Rats, Wistar; Superoxide Dismutase | 2001 |
Antioxidants attenuate early up regulation of retinal vascular endothelial growth factor in streptozotocin-diabetic rats.
Topics: Alternative Splicing; Animals; Antioxidants; Ascorbic Acid; Blood Glucose; Dehydroascorbic Acid; Diabetes Mellitus, Experimental; Endothelial Growth Factors; Fructose; Gene Expression Regulation; Glucose; Glutathione; Lipid Peroxidation; Lymphokines; Malondialdehyde; Rats; Retina; RNA, Messenger; Sorbitol; Taurine; Thioctic Acid; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factors | 2001 |
Taurine counteracts oxidative stress and nerve growth factor deficit in early experimental diabetic neuropathy.
Topics: Aldehydes; Animals; Ascorbic Acid; Blood Glucose; Body Weight; Diabetes Mellitus, Experimental; Diabetic Neuropathies; Dietary Supplements; Disease Models, Animal; Glutathione; Lipid Peroxidation; Male; Malondialdehyde; Nerve Growth Factor; Oxidative Stress; Rats; Rats, Wistar; Sciatic Nerve; Streptozocin; Taurine | 2001 |
Effect of phensuccinal on pancreatic beta-cells in rats with neonatally induced streptozotocin diabetes mellitus.
Topics: Animals; Animals, Newborn; Blood Glucose; Diabetes Mellitus, Experimental; Glutathione; Insulin; Insulin Secretion; Islets of Langerhans; Malondialdehyde; Rats; Rats, Wistar; Succinates | 2001 |
Alpha-lipoic acid attenuates hyperglycemia and prevents glomerular mesangial matrix expansion in diabetes.
Topics: Albuminuria; Animals; Antioxidants; Blood Glucose; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Female; Glomerular Mesangium; Glutathione; Hyperglycemia; Hypoglycemic Agents; Kidney Cortex; Malondialdehyde; Rats; Renal Insufficiency; Thioctic Acid; Transforming Growth Factor beta | 2002 |
Effects of the superoxide dismutase-mimetic compound tempol on endothelial dysfunction in streptozotocin-induced diabetic rats.
Topics: Acetylcholine; Animals; Antioxidants; Aorta; Blood Glucose; Body Weight; Cyclic GMP; Cyclic N-Oxides; Diabetes Mellitus, Experimental; Dinoprost; Dose-Response Relationship, Drug; Endothelium, Vascular; In Vitro Techniques; Male; Malondialdehyde; Rats; Rats, Sprague-Dawley; Spin Labels; Superoxides; Vasodilation; Vasodilator Agents | 2002 |
Influence of vitamin E on the levels of fatty acids and MDA in some tissues of diabetic rats.
Topics: Animals; Brain; Diabetes Mellitus, Experimental; Fatty Acids; Liver; Malondialdehyde; Muscle, Skeletal; Rats; Rats, Wistar; Tissue Distribution; Vitamin E | 2002 |
Comparative analysis of the protective effects of melatonin and vitamin E on streptozocin-induced diabetes mellitus.
Topics: Animals; Brain; Diabetes Mellitus, Experimental; Glutathione Peroxidase; Kidney; Lipid Peroxidation; Liver; Male; Malondialdehyde; Melatonin; Rats; Rats, Wistar; Streptozocin; Vitamin E | 2002 |
Changes in antioxidant status of lung tissue in experimental diabetes in rabbits.
Topics: Animals; Antioxidants; Arachidonic Acid; Catalase; Diabetes Mellitus, Experimental; Glucose; Glutathione; Glutathione Peroxidase; Lipid Peroxidation; Lung Diseases; Male; Malondialdehyde; Oxidation-Reduction; Oxidative Stress; Rabbits; Sulfhydryl Compounds; Superoxide Dismutase | 2002 |
Evidence of oxidative stress in the renal cortex of diabetic rats: favourable effect of vitamin E.
Topics: Animals; Blood Glucose; Diabetes Mellitus, Experimental; Glutathione Peroxidase; Glutathione Reductase; Glutathione Transferase; Kidney Cortex; Malondialdehyde; Oxidative Stress; Rats; Streptozocin; Superoxide Dismutase; Vitamin E | 2002 |
The effect of verapamil on the antioxidant defence system in diabetic kidney.
Topics: Albuminuria; Animals; Antioxidants; Basement Membrane; Blood Glucose; Body Weight; Catalase; Diabetes Mellitus, Experimental; Glutathione Peroxidase; Glycated Hemoglobin; Kidney; Kidney Glomerulus; Male; Malondialdehyde; Organ Size; Rats; Rats, Wistar; Superoxide Dismutase; Time Factors; Verapamil | 2002 |
[The effect of Coptis chinensis on lipid peroxidation and antioxidases activity in rats].
Topics: Animals; Blood Glucose; Brain; Catalase; Diabetes Mellitus, Experimental; Drugs, Chinese Herbal; Lipid Peroxidation; Male; Malondialdehyde; Rats; Rats, Wistar; Superoxide Dismutase | 1992 |
[Dynamics of glycosylated hemoglobin and malondialdehyde contents in experimental diabetes mellitus].
Topics: Animals; Blood Glucose; Diabetes Mellitus, Experimental; Dogs; Female; Glycated Hemoglobin; Insulin; Male; Malondialdehyde; Time Factors | 1992 |
Hepatic lipid peroxidation and trace elements--nutritional status in streptozotocin-induced diabetic rats.
Topics: Animals; Blood Glucose; Copper; Diabetes Mellitus, Experimental; Iron; Lipid Peroxidation; Liver; Male; Malondialdehyde; Nutritional Status; Rats; Trace Elements; Triglycerides; Zinc | 1992 |
Alterations of antioxidant tissue defense enzymes and related metabolic parameters in streptozotocin-diabetic rats--effects of iodine treatment.
Topics: Animals; Catalase; Cholesterol; Diabetes Mellitus, Experimental; Glutathione Peroxidase; Iodine; Lipid Peroxidation; Liver; Male; Malondialdehyde; Rats; Rats, Inbred Strains; Superoxide Dismutase; Thyroid Function Tests; Thyroid Hormones | 1992 |
Peroxidative changes in experimental diabetes mellitus.
Topics: Animals; Diabetes Mellitus, Experimental; Glutathione; Kidney; Liver; Male; Malondialdehyde; Myocardium; Peroxides; Rats; Rats, Inbred Strains | 1992 |
Lipid peroxidation in early experimental diabetes in rats: effects of diabetes and insulin.
Topics: Animals; Diabetes Mellitus, Experimental; Female; Insulin; Kidney; Lipid Peroxides; Liver; Malondialdehyde; Rats; Rats, Inbred Strains | 1992 |
Glomerular nonenzymatic glycosylation and lipid peroxide are increased in the early phase of streptozotocin-induced diabetic rats prior to major histopathologic alterations.
Topics: Animals; Diabetes Mellitus, Experimental; Glycosylation; Immunoglobulin G; Immunoglobulin M; Kidney Glomerulus; Lipid Peroxides; Male; Malondialdehyde; Prediabetic State; Rats; Rats, Inbred Strains; Time Factors | 1991 |
[Features of lipid peroxidation in the vitreous body and retina during intravitreal hemorrhaging in dithiosone-induced diabetes].
Topics: Animals; Antioxidants; Diabetes Mellitus, Experimental; Diabetic Retinopathy; Dithizone; Hydrogen Peroxide; Kinetics; Lipid Peroxidation; Malondialdehyde; Rabbits; Retina; Vitreous Body; Vitreous Hemorrhage | 1991 |
Oxygen free radical effects in sciatic nerve in experimental diabetes.
Topics: Animals; Blood Glucose; Body Weight; Diabetes Mellitus, Experimental; Diabetic Neuropathies; Free Radicals; Glycated Hemoglobin; Male; Malondialdehyde; Norepinephrine; Rats; Rats, Inbred Strains; Reference Values; Sciatic Nerve; Time Factors | 1991 |
The increase in lipid peroxidation in diabetic rat lens can be reversed by oral sorbinil.
Topics: Administration, Oral; Aldehyde Reductase; Animals; Diabetes Mellitus, Experimental; Imidazoles; Imidazolidines; Insulin; Lens, Crystalline; Lipid Peroxides; Male; Malondialdehyde; Rats; Rats, Inbred Strains | 1990 |
Detection of malondialdehyde levels and superoxide dismutase activities in renal tissues of nonobese diabetic mice.
Topics: Animals; Diabetes Mellitus, Experimental; Kidney; Malonates; Malondialdehyde; Mice; Oxygen Consumption; Superoxide Dismutase | 1990 |
[Lipid peroxidation and cataract formation in experimental diabetes].
Topics: Animals; Cataract; Diabetes Mellitus, Experimental; Lens, Crystalline; Lipid Peroxidation; Malonates; Malondialdehyde; Rats | 1989 |
Antioxidant enzyme alterations in experimental and clinical diabetes.
Topics: Animals; Catalase; Diabetes Mellitus; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Erythrocytes, Abnormal; Glutathione; Glutathione Peroxidase; Glutathione Reductase; Humans; Malondialdehyde; Rats; Rats, Inbred Strains; Superoxide Dismutase | 1988 |
[Effect of insulin in liposomes on experimental subhepatic cholestasis].
Topics: Animals; Cholestasis; Diabetes Mellitus, Experimental; Disease Models, Animal; Dogs; Drug Evaluation, Preclinical; Insulin; Lipid Peroxides; Lipoproteins; Liposomes; Malondialdehyde; Time Factors | 1985 |