malic acid has been researched along with Sicca Syndrome in 2 studies
malic acid : A 2-hydroxydicarboxylic acid that is succinic acid in which one of the hydrogens attached to a carbon is replaced by a hydroxy group.
2-hydroxydicarboxylic acid : Any dicarboxylic acid carrying a hydroxy group on the carbon atom at position alpha to the carboxy group.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The malic acid treatment resulted in a greater effect size and percentage improvement than citric acid mouthwash." | 2.94 | Patient-related outcomes in Sjögren syndrome treated with stimulants of salivary secretion: Randomized clinical trial. ( Amaral, JPAR; Barcelos, F; da Mata, ADSP; Marques, DNDS; Pereira, RMN; Thomson, WM; Vaz Patto, J, 2020) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (50.00) | 24.3611 |
| 2020's | 1 (50.00) | 2.80 |
| Authors | Studies |
|---|---|
| da Mata, ADSP | 1 |
| Amaral, JPAR | 1 |
| Thomson, WM | 1 |
| Barcelos, F | 1 |
| Vaz Patto, J | 1 |
| Pereira, RMN | 1 |
| Marques, DNDS | 1 |
| da Silva Marques, DN | 1 |
| da Mata, AD | 1 |
| Patto, JM | 1 |
| Barcelos, FA | 1 |
| de Almeida Rato Amaral, JP | 1 |
| de Oliveira, MC | 1 |
| Ferreira, CG | 1 |
2 trials available for malic acid and Sicca Syndrome
| Article | Year |
|---|---|
Patient-related outcomes in Sjögren syndrome treated with stimulants of salivary secretion: Randomized clinical trial.
Topics: Citric Acid; Female; Humans; Malates; Male; Middle Aged; Mouthwashes; Quality of Life; Saliva; Saliv | 2020 |
Effects of gustatory stimulants of salivary secretion on salivary pH and flow in patients with Sjögren's syndrome: a randomized controlled trial.
Topics: Adult; Buffers; Citric Acid; Double-Blind Method; Female; Fluorides; Follow-Up Studies; Humans; Hydr | 2011 |