Page last updated: 2024-10-17

malic acid and Pregnancy

malic acid has been researched along with Pregnancy in 15 studies

malic acid : A 2-hydroxydicarboxylic acid that is succinic acid in which one of the hydrogens attached to a carbon is replaced by a hydroxy group.
2-hydroxydicarboxylic acid : Any dicarboxylic acid carrying a hydroxy group on the carbon atom at position alpha to the carboxy group.

Pregnancy: The status during which female mammals carry their developing young (EMBRYOS or FETUSES) in utero before birth, beginning from FERTILIZATION to BIRTH.

Research Excerpts

ExcerptRelevanceReference
"l-malic acid (MA) was previously reported to improve antioxidant capacity and aerobic metabolism."1.91Maternal consumption of l-malic acid enriched diets improves antioxidant capacity and glucose metabolism in offspring by regulating the gut microbiota. ( Guo, J; He, L; Jiang, G; Wang, Y; Yan, E; Yin, J; Zhang, P; Zhang, X, 2023)
" The results showed that no pathological, toxic feces and urine changes were observed in clinical signs of parental and fetal rats in chromium malate groups."1.42Evaluation of the Reproductive Toxicity, Glycometabolism, Glycometabolism-Related Enzyme Levels and Lipid Metabolism of Chromium Malate Supplementation in Sprague-Dawley Rats. ( Bao, Y; Feng, W; Huang, J; Mao, G; Wang, W; Wu, X; Yang, L; Zhang, W; Zhao, T; Zhou, Z, 2015)

Research

Studies (15)

TimeframeStudies, this research(%)All Research%
pre-19904 (26.67)18.7374
1990's1 (6.67)18.2507
2000's5 (33.33)29.6817
2010's2 (13.33)24.3611
2020's3 (20.00)2.80

Authors

AuthorsStudies
Selek, S1
Gul, AZ1
Atakul, N1
Meydan, S1
Sarıkaya, A1
Koktasoglu, F1
Demirel, M1
Zheng, J1
Tang, X1
Han, TL1
Zhang, C1
Zhang, S1
Zhang, P1
Jiang, G1
Wang, Y1
Yan, E1
He, L1
Guo, J1
Yin, J1
Zhang, X1
Feng, W1
Zhang, W1
Zhao, T1
Mao, G1
Wang, W1
Wu, X2
Zhou, Z1
Huang, J1
Bao, Y1
Yang, L1
Mitchell, M1
Cashman, KS1
Gardner, DK2
Thompson, JG1
Lane, M2
Llorente-Folch, I1
Sahún, I1
Contreras, L1
Casarejos, MJ1
Grau, JM1
Saheki, T1
Mena, MA1
Satrústegui, J1
Dierssen, M1
Pardo, B1
Ain, R1
Seshagiri, PB1
Nakai, A1
Taniuchi, Y1
Asakura, H1
Oya, A1
Yokota, A1
Koshino, T1
Araki, T1
Martínez, F2
Uribe, A2
Espinosa-García, MT1
Flores-Herrera, O2
García-Pérez, C1
Milán, R2
Teresa Espinosa-García, M1
Gracía-Pérez, C1
Nyquist-Battie, C1
Freter, M1
Sussman, I1
Matschinsky, FM1
Swierczyński, J2
Aleksandrowicz, Z1
Zelewski, L2
Klimek, J1

Other Studies

15 other studies available for malic acid and Pregnancy

ArticleYear
Investigation of serum enzyme activities and oxidative stress markers in preeclampsia: a multiparameter analysis.
    Ginekologia polska, 2023, Volume: 94, Issue:6

    Topics: Antioxidants; Female; Glutamate Dehydrogenase; Humans; Isocitrates; Malates; Oxidative Stress; Pre-E

2023
Metabolomics analysis of serum metabolites during endometrial transformation: association with recurrent implantation failure in hormonal replacement therapy-frozen embryo transfers cycles.
    Journal of assisted reproduction and genetics, 2023, Volume: 40, Issue:10

    Topics: Amino Acids; Case-Control Studies; Embryo Implantation; Embryo Transfer; Endometrium; Female; Humans

2023
Maternal consumption of l-malic acid enriched diets improves antioxidant capacity and glucose metabolism in offspring by regulating the gut microbiota.
    Redox biology, 2023, Volume: 67

    Topics: Animals; Antioxidants; Ascorbic Acid; Diet, High-Fat; Female; Gastrointestinal Microbiome; Glucose;

2023
Evaluation of the Reproductive Toxicity, Glycometabolism, Glycometabolism-Related Enzyme Levels and Lipid Metabolism of Chromium Malate Supplementation in Sprague-Dawley Rats.
    Biological trace element research, 2015, Volume: 168, Issue:1

    Topics: Animals; Chromium Compounds; Diabetes Mellitus, Experimental; Dietary Supplements; Dose-Response Rel

2015
Disruption of mitochondrial malate-aspartate shuttle activity in mouse blastocysts impairs viability and fetal growth.
    Biology of reproduction, 2009, Volume: 80, Issue:2

    Topics: Aminooxyacetic Acid; Animals; Aspartate Aminotransferase, Cytoplasmic; Aspartic Acid; Biological Tra

2009
AGC1-malate aspartate shuttle activity is critical for dopamine handling in the nigrostriatal pathway.
    Journal of neurochemistry, 2013, Volume: 124, Issue:3

    Topics: Amino Acid Transport Systems, Acidic; Animals; Antiporters; Aspartic Acid; Corpus Striatum; Dopamine

2013
Mitochondrial malate-aspartate shuttle regulates mouse embryo nutrient consumption.
    The Journal of biological chemistry, 2005, May-06, Volume: 280, Issue:18

    Topics: Animals; Aspartic Acid; Biological Transport; Embryo, Mammalian; Embryonic Development; Female; Mala

2005
Succinate and malate improve development of hamster eight-cell embryos in vitro: confirmation of viability by embryo transfer.
    Molecular reproduction and development, 1997, Volume: 47, Issue:4

    Topics: Animals; Blastocyst; Cell Count; Cell Survival; Cells, Cultured; Cricetinae; Culture Media; Embryo T

1997
Developmental changes in mitochondrial activity and energy metabolism in fetal and neonatal rat brain.
    Brain research. Developmental brain research, 2000, May-11, Volume: 121, Issue:1

    Topics: Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Animals, Newborn; B

2000
Calcium modulates the ATP and ADP hydrolysis in human placental mitochondria.
    The international journal of biochemistry & cell biology, 2002, Volume: 34, Issue:8

    Topics: Adenosine Diphosphate; Adenosine Triphosphate; Calcium; Female; Humans; Hydrolysis; Ketoglutaric Aci

2002
Differential effects of magnesium on the hydrolysis of ADP and ATP in human term placenta. Effect of substrates and potassium.
    The international journal of biochemistry & cell biology, 2002, Volume: 34, Issue:8

    Topics: Adenosine Diphosphate; Adenosine Triphosphate; Female; Humans; Hydrolysis; Isocitrates; Ketoglutaric

2002
Cardiac mitochondrial abnormalities in a mouse model of the fetal alcohol syndrome.
    Alcoholism, clinical and experimental research, 1988, Volume: 12, Issue:2

    Topics: Animals; Animals, Newborn; Electron Transport Complex IV; Ethanol; Female; Fetal Alcohol Spectrum Di

1988
Diabetes affects sorbitol and myo-inositol levels of neuroectodermal tissue during embryogenesis in rat.
    Diabetes, 1988, Volume: 37, Issue:7

    Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Body Weight; Creatine; Diabetes Mellitus, Ex

1988
Stimulatory effect of ADP, ATP, NAD(P) on pyruvate production from malate by uncoupled human placental mitochondria.
    Biochemical medicine and metabolic biology, 1987, Volume: 38, Issue:2

    Topics: Adenosine Diphosphate; Adenosine Triphosphate; Female; Humans; Hydrogen-Ion Concentration; In Vitro

1987
The role of malic enzyme in the malate dependent biosynthesis of progesterone in the mitochondrial fraction of human term placenta.
    Journal of steroid biochemistry, 1985, Volume: 22, Issue:3

    Topics: Citrates; Citric Acid; Female; Humans; Malate Dehydrogenase; Malates; Mitochondria; NAD; NADP; Place

1985