malic acid has been researched along with Necrosis in 2 studies
malic acid : A 2-hydroxydicarboxylic acid that is succinic acid in which one of the hydrogens attached to a carbon is replaced by a hydroxy group.
2-hydroxydicarboxylic acid : Any dicarboxylic acid carrying a hydroxy group on the carbon atom at position alpha to the carboxy group.
Necrosis: The death of cells in an organ or tissue due to disease, injury or failure of the blood supply.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Twenty-four hours after treating implanted lymphoma tumors with etoposide, at which point there were significant levels of tumor cell necrosis, there was a 2." | 1.35 | Production of hyperpolarized [1,4-13C2]malate from [1,4-13C2]fumarate is a marker of cell necrosis and treatment response in tumors. ( Bohndiek, SE; Brindle, KM; Gallagher, FA; Gisselsson, A; Hansson, G; Hu, DE; Jensen, PR; Karlsson, M; Kettunen, MI; Lerche, MH; Nelson, SK; Peitersen, T; Witney, TH; Zandt, RI, 2009) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (50.00) | 29.6817 |
| 2010's | 1 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Wang, C | 1 |
| Chen, H | 1 |
| Zhang, M | 1 |
| Zhang, J | 1 |
| Wei, X | 1 |
| Ying, W | 1 |
| Gallagher, FA | 1 |
| Kettunen, MI | 1 |
| Hu, DE | 1 |
| Jensen, PR | 1 |
| Zandt, RI | 1 |
| Karlsson, M | 1 |
| Gisselsson, A | 1 |
| Nelson, SK | 1 |
| Witney, TH | 1 |
| Bohndiek, SE | 1 |
| Hansson, G | 1 |
| Peitersen, T | 1 |
| Lerche, MH | 1 |
| Brindle, KM | 1 |
2 other studies available for malic acid and Necrosis
| Article | Year |
|---|---|
Malate-aspartate shuttle inhibitor aminooxyacetic acid leads to decreased intracellular ATP levels and altered cell cycle of C6 glioma cells by inhibiting glycolysis.
Topics: Adenosine Triphosphate; Aminooxyacetic Acid; Animals; Antineoplastic Agents; Apoptosis; Aspartic Aci | 2016 |
Production of hyperpolarized [1,4-13C2]malate from [1,4-13C2]fumarate is a marker of cell necrosis and treatment response in tumors.
Topics: Animals; Antineoplastic Agents, Phytogenic; Biomarkers, Tumor; Carbon Isotopes; Etoposide; Female; F | 2009 |