malic acid has been researched along with Insulin Sensitivity in 4 studies
malic acid : A 2-hydroxydicarboxylic acid that is succinic acid in which one of the hydrogens attached to a carbon is replaced by a hydroxy group.
2-hydroxydicarboxylic acid : Any dicarboxylic acid carrying a hydroxy group on the carbon atom at position alpha to the carboxy group.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Our previous findings clearly suggested the role of duration of exposure to monocrotophos (MCP) in the development of insulin resistance." | 7.83 | Adaptive response of rat pancreatic β-cells to insulin resistance induced by monocrotophos: Biochemical evidence. ( Nagaraju, R; Rajini, PS, 2016) |
| "Our previous findings clearly suggested the role of duration of exposure to monocrotophos (MCP) in the development of insulin resistance." | 3.83 | Adaptive response of rat pancreatic β-cells to insulin resistance induced by monocrotophos: Biochemical evidence. ( Nagaraju, R; Rajini, PS, 2016) |
| "l-malic acid (MA) was previously reported to improve antioxidant capacity and aerobic metabolism." | 1.91 | Maternal consumption of l-malic acid enriched diets improves antioxidant capacity and glucose metabolism in offspring by regulating the gut microbiota. ( Guo, J; He, L; Jiang, G; Wang, Y; Yan, E; Yin, J; Zhang, P; Zhang, X, 2023) |
| "The pathogenesis of type 2 diabetes is characterized by impaired insulin action and increased hepatic glucose production (HGP)." | 1.39 | In vivo hyperpolarized carbon-13 magnetic resonance spectroscopy reveals increased pyruvate carboxylase flux in an insulin-resistant mouse model. ( Han, W; Lee, P; Leong, W; Lim, M; Radda, GK; Tan, T, 2013) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (25.00) | 29.6817 |
| 2010's | 2 (50.00) | 24.3611 |
| 2020's | 1 (25.00) | 2.80 |
| Authors | Studies |
|---|---|
| Zhang, P | 1 |
| Jiang, G | 1 |
| Wang, Y | 1 |
| Yan, E | 1 |
| He, L | 1 |
| Guo, J | 1 |
| Yin, J | 1 |
| Zhang, X | 1 |
| Nagaraju, R | 1 |
| Rajini, PS | 1 |
| Lee, P | 1 |
| Leong, W | 1 |
| Tan, T | 1 |
| Lim, M | 1 |
| Han, W | 1 |
| Radda, GK | 1 |
| Liu, YQ | 1 |
| Jetton, TL | 1 |
| Leahy, JL | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Effect of Fatty Liver on TCA Cycle Flux and the Pentose Phosphate Pathway (HP FFF)[NCT03480594] | 30 participants (Anticipated) | Observational | 2018-10-01 | Enrolling by invitation | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
4 other studies available for malic acid and Insulin Sensitivity
| Article | Year |
|---|---|
Maternal consumption of l-malic acid enriched diets improves antioxidant capacity and glucose metabolism in offspring by regulating the gut microbiota.
Topics: Animals; Antioxidants; Ascorbic Acid; Diet, High-Fat; Female; Gastrointestinal Microbiome; Glucose; | 2023 |
Adaptive response of rat pancreatic β-cells to insulin resistance induced by monocrotophos: Biochemical evidence.
Topics: Adaptation, Physiological; Adenosine Diphosphate; Adenosine Triphosphate; Animals; Blood Glucose; In | 2016 |
In vivo hyperpolarized carbon-13 magnetic resonance spectroscopy reveals increased pyruvate carboxylase flux in an insulin-resistant mouse model.
Topics: Animals; Aspartic Acid; Carbon Isotopes; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; | 2013 |
beta-Cell adaptation to insulin resistance. Increased pyruvate carboxylase and malate-pyruvate shuttle activity in islets of nondiabetic Zucker fatty rats.
Topics: Animals; Body Weight; Citric Acid; Dose-Response Relationship, Drug; Glucose; Glycerol; Insulin Resi | 2002 |