Page last updated: 2024-10-17

malic acid and Fibromyalgia

malic acid has been researched along with Fibromyalgia in 3 studies

malic acid : A 2-hydroxydicarboxylic acid that is succinic acid in which one of the hydrogens attached to a carbon is replaced by a hydroxy group.
2-hydroxydicarboxylic acid : Any dicarboxylic acid carrying a hydroxy group on the carbon atom at position alpha to the carboxy group.

Fibromyalgia: A common nonarticular rheumatic syndrome characterized by myalgia and multiple points of focal muscle tenderness to palpation (trigger points). Muscle pain is typically aggravated by inactivity or exposure to cold. This condition is often associated with general symptoms, such as sleep disturbances, fatigue, stiffness, HEADACHES, and occasionally DEPRESSION. There is significant overlap between fibromyalgia and the chronic fatigue syndrome (FATIGUE SYNDROME, CHRONIC). Fibromyalgia may arise as a primary or secondary disease process. It is most frequent in females aged 20 to 50 years. (From Adams et al., Principles of Neurology, 6th ed, p1494-95)

Research Excerpts

ExcerptRelevanceReference
" Our conclusion is that the use of magnesium and malic acid in patients with fibromyalgia makes little or no difference on pain and on depressive symptoms."9.01Magnesium and malic acid supplement for fibromyalgia. ( Ferreira, I; Moore, P; Ortigoza, Á, 2019)
"To study the efficacy and safety of Super Malic, a proprietary tablet containing malic acid (200 mg) and magnesium (50 mg), in treatment of primary fibromyalgia syndrome (FM)."5.08Treatment of fibromyalgia syndrome with Super Malic: a randomized, double blind, placebo controlled, crossover pilot study. ( Abraham, GE; Flechas, JD; Michalek, JE; Russell, IJ, 1995)
" Our conclusion is that the use of magnesium and malic acid in patients with fibromyalgia makes little or no difference on pain and on depressive symptoms."5.01Magnesium and malic acid supplement for fibromyalgia. ( Ferreira, I; Moore, P; Ortigoza, Á, 2019)
"Fibromyalgia is a chronic widespread pain condition affecting millions of people worldwide."2.58Combination pharmacotherapy for the treatment of fibromyalgia in adults. ( Gilron, I; Moore, RA; Shum, B; Thorpe, J; Wiffen, PJ, 2018)

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (33.33)18.2507
2000's0 (0.00)29.6817
2010's2 (66.67)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Thorpe, J1
Shum, B1
Moore, RA1
Wiffen, PJ1
Gilron, I1
Ferreira, I1
Ortigoza, Á1
Moore, P1
Russell, IJ1
Michalek, JE1
Flechas, JD1
Abraham, GE1

Reviews

2 reviews available for malic acid and Fibromyalgia

ArticleYear
Combination pharmacotherapy for the treatment of fibromyalgia in adults.
    The Cochrane database of systematic reviews, 2018, 02-19, Volume: 2

    Topics: 5-Hydroxytryptophan; Acetaminophen; Adult; Amitriptyline; Anti-Inflammatory Agents, Non-Steroidal; A

2018
Magnesium and malic acid supplement for fibromyalgia.
    Medwave, 2019, May-28, Volume: 19, Issue:4

    Topics: Databases, Factual; Dietary Supplements; Fibromyalgia; Humans; Magnesium; Malates; Randomized Contro

2019

Trials

1 trial available for malic acid and Fibromyalgia

ArticleYear
Treatment of fibromyalgia syndrome with Super Malic: a randomized, double blind, placebo controlled, crossover pilot study.
    The Journal of rheumatology, 1995, Volume: 22, Issue:5

    Topics: Cross-Over Studies; Double-Blind Method; Drug Administration Schedule; Drug Combinations; Female; Fi

1995