malic acid has been researched along with Cardiac Hypertrophy in 3 studies
malic acid : A 2-hydroxydicarboxylic acid that is succinic acid in which one of the hydrogens attached to a carbon is replaced by a hydroxy group.
2-hydroxydicarboxylic acid : Any dicarboxylic acid carrying a hydroxy group on the carbon atom at position alpha to the carboxy group.
Cardiac Hypertrophy: Enlargement of the HEART due to chamber HYPERTROPHY, an increase in wall thickness without an increase in the number of cells (MYOCYTES, CARDIAC). It is the result of increase in myocyte size, mitochondrial and myofibrillar mass, as well as changes in extracellular matrix.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Mice with juvenile visceral steatosis (JVS) develop remarkable cardiac hypertrophy and exhibit an increased number of mitochondria in their heart." | 1.32 | Functional disorders of the oxidative phosphorylation system in the heart mitochondria of mice with juvenile visceral steatosis. ( Arakaki, N; Higuti, T; Himeda, T; Kuwajima, M; Morokami, K; Shibata, H; Suenaga, M, 2003) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 3 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Suenaga, M | 1 |
| Arakaki, N | 1 |
| Morokami, K | 1 |
| Himeda, T | 1 |
| Shibata, H | 1 |
| Kuwajima, M | 1 |
| Higuti, T | 1 |
| Ralphe, JC | 1 |
| Bedell, K | 1 |
| Segar, JL | 2 |
| Scholz, TD | 2 |
| Rupert, BE | 1 |
| Schutte, BC | 1 |
3 other studies available for malic acid and Cardiac Hypertrophy
| Article | Year |
|---|---|
Functional disorders of the oxidative phosphorylation system in the heart mitochondria of mice with juvenile visceral steatosis.
Topics: Adenosine Triphosphatases; Animals; Blotting, Western; Cardiomegaly; Cytochromes; Disease Models, An | 2003 |
Correlation between myocardial malate/aspartate shuttle activity and EAAT1 protein expression in hyper- and hypothyroidism.
Topics: Amino Acid Transport System X-AG; Animals; Aspartic Acid; Cardiomegaly; Excitatory Amino Acid Transp | 2005 |
Metabolic adaptation of the hypertrophied heart: role of the malate/aspartate and alpha-glycerophosphate shuttles.
Topics: Adenosine Triphosphate; Animals; Aorta; Aspartic Acid; Atrial Natriuretic Factor; Blotting, Northern | 2000 |