malic acid has been researched along with Acute Kidney Failure in 6 studies
malic acid : A 2-hydroxydicarboxylic acid that is succinic acid in which one of the hydrogens attached to a carbon is replaced by a hydroxy group.
2-hydroxydicarboxylic acid : Any dicarboxylic acid carrying a hydroxy group on the carbon atom at position alpha to the carboxy group.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Diethylene glycol (DEG) has caused many cases of acute kidney injury and deaths worldwide." | 3.83 | Diglycolic acid, the toxic metabolite of diethylene glycol, chelates calcium and produces renal mitochondrial dysfunction in vitro. ( Aw, TY; Conrad, T; Landry, GM; McMartin, KE; Nichols, R, 2016) |
| " This drug, therefore affects the bioavailability of two major respiratory complex I substrates which would normally contribute substantially to supplying the reducing equivalents for mitochondrial electron transport for generation of ATP in the renal cell." | 1.33 | Action of diclofenac on kidney mitochondria and cells. ( Halliwell, B; Ng, LE; Vincent, AS; Wong, KP, 2006) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (33.33) | 29.6817 |
| 2010's | 3 (50.00) | 24.3611 |
| 2020's | 1 (16.67) | 2.80 |
| Authors | Studies |
|---|---|
| Mueller, F | 1 |
| Teloh-Benger, JK | 1 |
| Hussmann, B | 1 |
| Lendemans, S | 1 |
| Waack, IN | 1 |
| Conrad, T | 1 |
| Landry, GM | 1 |
| Aw, TY | 1 |
| Nichols, R | 1 |
| McMartin, KE | 1 |
| Nielsen, PM | 1 |
| Eldirdiri, A | 1 |
| Bertelsen, LB | 1 |
| Jørgensen, HS | 1 |
| Ardenkjaer-Larsen, JH | 1 |
| Laustsen, C | 1 |
| Bienholz, A | 1 |
| Petrat, F | 1 |
| Wenzel, P | 1 |
| Ickerott, P | 1 |
| Weinberg, JM | 2 |
| Witzke, O | 1 |
| Kribben, A | 2 |
| de Groot, H | 1 |
| Feldkamp, T | 2 |
| Roeser, NF | 1 |
| Senter, RA | 1 |
| Kemner, S | 1 |
| Venkatachalam, MA | 1 |
| Nissim, I | 1 |
| Ng, LE | 1 |
| Vincent, AS | 1 |
| Halliwell, B | 1 |
| Wong, KP | 1 |
6 other studies available for malic acid and Acute Kidney Failure
| Article | Year |
|---|---|
Malate Protects the Kidneys From Hemorrhagic Shock-Induced Injury in an Experimental Rat Model.
Topics: Acute Kidney Injury; Animals; Disease Models, Animal; Fluid Therapy; Humans; Infusions, Intravenous; | 2020 |
Diglycolic acid, the toxic metabolite of diethylene glycol, chelates calcium and produces renal mitochondrial dysfunction in vitro.
Topics: Acute Kidney Injury; Animals; Calcium; Cells, Cultured; Chelating Agents; Egtazic Acid; Ethylene Gly | 2016 |
Fumarase activity: an in vivo and in vitro biomarker for acute kidney injury.
Topics: Acute Kidney Injury; Animals; Biomarkers; Fumarate Hydratase; Malates; Male; Rats; Rats, Wistar | 2017 |
Adverse effects of α-ketoglutarate/malate in a rat model of acute kidney injury.
Topics: Acute Kidney Injury; Animals; Blood Pressure; Cell Adhesion Molecules; Disease Models, Animal; Heart | 2012 |
Preservation of complex I function during hypoxia-reoxygenation-induced mitochondrial injury in proximal tubules.
Topics: Acute Kidney Injury; Animals; Citric Acid Cycle; Cytosol; Electron Transport Complex I; Energy Metab | 2004 |
Action of diclofenac on kidney mitochondria and cells.
Topics: Acute Kidney Injury; Adenosine Triphosphate; Animals; Aspartic Acid; Benzimidazoles; Carbocyanines; | 2006 |