malic acid has been researched along with Acidemia Propionic in 2 studies
malic acid : A 2-hydroxydicarboxylic acid that is succinic acid in which one of the hydrogens attached to a carbon is replaced by a hydroxy group.
2-hydroxydicarboxylic acid : Any dicarboxylic acid carrying a hydroxy group on the carbon atom at position alpha to the carboxy group.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Accumulation of 2-methylcitric acid (2MCA) is observed in methylmalonic and propionic acidemias, which are clinically characterized by severe neurological symptoms." | 3.83 | 2-Methylcitric acid impairs glutamate metabolism and induces permeability transition in brain mitochondria. ( Amaral, AU; Castilho, RF; Cecatto, C; Wajner, M, 2016) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (50.00) | 24.3611 |
| 2020's | 1 (50.00) | 2.80 |
| Authors | Studies |
|---|---|
| Roginski, AC | 1 |
| Zemniaçak, ÂB | 1 |
| Marschner, RA | 1 |
| Wajner, SM | 1 |
| Ribeiro, RT | 1 |
| Wajner, M | 2 |
| Amaral, AU | 2 |
| Cecatto, C | 1 |
| Castilho, RF | 1 |
2 other studies available for malic acid and Acidemia Propionic
| Article | Year |
|---|---|
Disruption of mitochondrial functions involving mitochondrial permeability transition pore opening caused by maleic acid in rat kidney.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Calcium; Cyclosporine; Glutamic Acid; HEK293 | 2022 |
2-Methylcitric acid impairs glutamate metabolism and induces permeability transition in brain mitochondria.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Amino Acid Metabolism, Inborn Errors; Animals; Brain; | 2016 |