malbrancheamide has been researched along with Hypertrophy* in 1 studies
1 other study(ies) available for malbrancheamide and Hypertrophy
Article | Year |
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Perturbation of the interactions of calmodulin with GRK5 using a natural product chemical probe.
G protein-coupled receptor (GPCR) kinases (GRKs) are responsible for initiating desensitization of activated GPCRs. GRK5 is potently inhibited by the calcium-sensing protein calmodulin (CaM), which leads to nuclear translocation of GRK5 and promotion of cardiac hypertrophy. Herein, we report the architecture of the Ca Topics: Biological Products; Calcium; Calmodulin; Cell Nucleus; Enzyme Activation; G-Protein-Coupled Receptor Kinase 5; Hypertrophy; Indole Alkaloids; Models, Biological; Myocytes, Cardiac; Phosphorylation; Protein Domains; Protein Transport; Substrate Specificity | 2019 |