malathion and Scalp Dermatoses studies

Malathion: A wide spectrum aliphatic organophosphate insecticide widely used for both domestic and commercial agricultural purposes.
malathion : A racemate comprising equimolar amounts of (R) and (S)-malathion. It is a broad spectrum organophosphate proinsecticide used to control a wide range of pests including Coleoptera, Diptera, fruit flies, mosquitos and spider mites.
diethyl 2-[(dimethoxyphosphorothioyl)thio]succinate : A diester that is diethyl succinate in which position 2 is substituted by a (dimethoxyphosphorothioyl)thio group.

Research Excerpts

Excerpt	Relevance	Reference
"Malathion is an under-recognized and under-utilized therapy for head lice and scabies largely due to misperceptions about its safety profile."	8.85	Malathion for head lice and scabies: treatment and safety considerations. ( Idriss, S; Levitt, J, 2009)
"Malathion is an under-recognized and under-utilized therapy for head lice and scabies largely due to misperceptions about its safety profile."	4.85	Malathion for head lice and scabies: treatment and safety considerations. ( Idriss, S; Levitt, J, 2009)
" Adverse events were limited to itching or stinging."	2.77	Safety and efficacy of a non-pesticide-based head lice treatment: results of a randomised comparative trial in children. ( Barnes, TM; Greive, KA; Lui, AH; Oppenheim, VM, 2012)
"Malathion lotion was twice as effective as bug-busting, even in an area with intermediate resistance."	2.69	Comparison of wet combing with malathion for treatment of head lice in the UK: a pragmatic randomised controlled trial. ( Casey, D; Morgan, DA; Petrovic, M; Roberts, RJ, 2000)
" In addition, the Food and Drug Administration recently warned of potentially serious adverse effects associated with lindane and recommended strict controls for its use."	2.42	Relationship of treatment-resistant head lice to the safety and efficacy of pediculicides. ( Burkhart, CG, 2004)
"Scabies is a common condition in New Zealand but scalp infestation by the mite is not often considered."	1.39	Scalp involvement by Sarcoptes scabiei var hominis resembling seborrhoeic dermatitis in two immunocompromised patients with systemic lupus erythematosus. ( Birry, A; Jarrett, P, 2013)
"Malathion shampoo was also provided for all family members."	1.37	Clinical response and safety of malathion shampoo for treatment of head lice in a primary school. ( Chatproedprai, S; Tempark, T; Wananukul, S; Wananukul, W, 2011)
"Malathion resistance was not observed in this study."	1.32	Permethrin-resistant human head lice, Pediculus capitis, and their treatment. ( Brown, L; Clark, JM; Gao, JR; Lee, SH; Taplin, D; Yoon, KS, 2003)

Timeframe	Studies, this research(%)	All Research%
pre-1990	2 (4.08)	18.7374
1990's	9 (18.37)	18.2507
2000's	30 (61.22)	29.6817
2010's	8 (16.33)	24.3611
2020's	0 (0.00)	2.80

Authors	Studies
Coscione, S	1
Kositz, C	1
Marks, M	1
Fancelli, C	1
Prato, M	1
Montagnani, C	1
Pierattelli, M	1
Becherucci, P	1
Chiappini, E	1
de Martino, M	1
Galli, L	1
Birry, A	1
Jarrett, P	1
Burgess, IF	1
Heymann, WR	1
Idriss, S	1
Levitt, J	1
Chosidow, O	1
Giraudeau, B	1
Cottrell, J	1
Izri, A	1
Hofmann, R	1
Mann, SG	1
Burgess, I	2
Rutman, H	1
Nofal, A	1
Wananukul, S	1
Chatproedprai, S	1
Tempark, T	1
Wananukul, W	1
Greive, KA	1
Lui, AH	1
Barnes, TM	1
Oppenheim, VM	1
Mumcuoglu, KY	2
Miller, J	1
Zamir, C	1
Zentner, G	2
Helbin, V	2
Ingber, A	1
Meinking, TL	3
Burkhart, CG	4
Burkhart, CN	3
Jones, KN	1
English, JC	1
Smith, S	1
Smith, G	1
Heatlie, H	1
Bashford, J	1
Ashcroft, D	1
Millson, D	1
Yoon, KS	1
Gao, JR	1
Lee, SH	1
Clark, JM	1
Brown, L	1
Taplin, D	2
Hill, N	2
Moor, G	1
Cameron, MM	1
Butlin, A	1
Preston, S	1
Williamson, MS	1
Bass, C	1
Cohen, R	1
Ben-Ishai, F	1
Ingberg, A	1
Dodd, CS	4
Oliveira, FA	1
Speare, R	1
Heukelbach, J	1
Castillero, PM	1
Spiegel, J	1
Mercer, S	1
Rivera, AA	1
Schachner, L	1
Vander Stichele, RH	2
Dezeure, EM	1
Bogaert, MG	2
Izri, MA	1
Brière, C	1
van der Laan, JR	1
Smit, RB	1
Eichenfield, LF	1
Colon-Fontanez, F	1
Downs, AM	2
Stafford, KA	2
Harvey, I	1
Coles, GC	2
Spirén, A	1
Svensson, A	1
Jörgensen, E	1
Elgart, ML	1
Chew, AL	1
Bashir, SJ	1
Maibach, HI	1
Roberts, RJ	2
Casey, D	1
Morgan, DA	1
Petrovic, M	1
Ibarra, J	1
Fry, F	1
Wickenden, C	1
Richards, SM	1
Entzel, P	2
Villar, ME	2
Vicaria, M	1
Lemard, GA	1
Porcelain, SL	1
Serrano, L	1
Hard, B	1
Lemard, G	1
Rivera, E	1

Trial			Phase	Enrollment	Study Type	Start Date	Status
A Randomised, Double-Blind, Multicentre Study to Compare the Efficacy and Tolerability of Oral Ivermectin to Malathion 0.5% Lotion in the Treatment of Head Lice Infestation[NCT00819520]			Phase 3	812 participants (Actual)	Interventional	2004-02-29	Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Article	Year
Head lice. BMJ clinical evidence, 2009, Jan-14, Volume: 2009 Topics: Administration, Oral; Animals; Humans; Lice Infestations; Malathion; Pediculus; Permethrin; Scalp De	2009
Malathion for head lice and scabies: treatment and safety considerations. Journal of drugs in dermatology : JDD, 2009, Volume: 8, Issue:8 Topics: Animals; Drug Resistance, Multiple; Humans; Insecticides; Lice Infestations; Malathion; Pediculus; S	2009
Relationship of treatment-resistant head lice to the safety and efficacy of pediculicides. Mayo Clinic proceedings, 2004, Volume: 79, Issue:5 Topics: Animals; Hexachlorocyclohexane; Humans; Insecticides; Lice Infestations; Malathion; Pediculus; Perme	2004
Head lice. Clinical evidence, 2005, Issue:14 Topics: Animals; Humans; Insecticides; Lice Infestations; Malathion; Pediculus; Permethrin; Scalp Dermatoses	2005
Head lice therapies revisited. Dermatology online journal, 2006, Oct-31, Volume: 12, Issue:6 Topics: Animals; Humans; Insecticide Resistance; Insecticides; Ivermectin; Lice Infestations; Malathion; Ped	2006
WITHDRAWN: Interventions for treating headlice. The Cochrane database of systematic reviews, 2007, Jul-18, Issue:4 Topics: Adult; Animals; Antiparasitic Agents; Carbaryl; Health Education; Humans; Hygiene; Lice Infestations	2007
Systematic review of clinical efficacy of topical treatments for head lice. BMJ (Clinical research ed.), 1995, Sep-02, Volume: 311, Issue:7005 Topics: Administration, Topical; Carbaryl; Hexachlorocyclohexane; Humans; Insecticides; Lice Infestations; M	1995
Treatment of head lice. The Pediatric infectious disease journal, 1998, Volume: 17, Issue:5 Topics: Adolescent; Animals; Child; Child, Preschool; Hexachlorocyclohexane; Humans; Insecticide Resistance;	1998
Interventions for treating headlice. The Cochrane database of systematic reviews, 2000, Issue:2 Topics: Adult; Animals; Antiparasitic Agents; Carbaryl; Health Education; Humans; Hygiene; Lice Infestations	2000
Interventions for treating head lice. The Cochrane database of systematic reviews, 2001, Issue:2 Topics: Adult; Animals; Antiparasitic Agents; Carbaryl; Child; Humans; Lice Infestations; Malathion; Patient	2001
Interventions for treating headlice. The Cochrane database of systematic reviews, 2001, Issue:3 Topics: Adult; Animals; Antiparasitic Agents; Carbaryl; Health Education; Humans; Hygiene; Lice Infestations	2001
Clinical practice. Head lice. The New England journal of medicine, 2002, May-23, Volume: 346, Issue:21 Topics: Animals; Child; Diagnostic Errors; Drug Resistance; Female; Humans; Insecticides; Lice Infestations;	2002

Article	Year
Oral ivermectin versus malathion lotion for difficult-to-treat head lice. The New England journal of medicine, 2010, Mar-11, Volume: 362, Issue:10 Topics: Administration, Oral; Administration, Topical; Adolescent; Animals; Child; Child, Preschool; Double-	2010
Oral ivermectin for head lice: a comparison with 0.5 % topical malathion lotion. Journal der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG, 2010, Volume: 8, Issue:12 Topics: Administration, Oral; Administration, Topical; Adolescent; Animals; Child; Female; Humans; Insectici	2010
Safety and efficacy of a non-pesticide-based head lice treatment: results of a randomised comparative trial in children. The Australasian journal of dermatology, 2012, Volume: 53, Issue:4 Topics: Adolescent; Animals; Betaine; Child; Child, Preschool; Cyclohexanols; Eucalyptol; Female; Hair Prepa	2012
The in vivo pediculicidal efficacy of a natural remedy. The Israel Medical Association journal : IMAJ, 2002, Volume: 4, Issue:10 Topics: Adolescent; Animals; Chi-Square Distribution; Child; Coconut Oil; Drug Combinations; Follow-Up Studi	2002
Single blind, randomised, comparative study of the Bug Buster kit and over the counter pediculicide treatments against head lice in the United Kingdom. BMJ (Clinical research ed.), 2005, Aug-13, Volume: 331, Issue:7513 Topics: Adolescent; Animals; Child; Child, Preschool; Hair Preparations; Humans; Hygiene; Infant; Insecticid	2005
[The in vivo pediculicidal efficac of Prioderm Cream Shampoo formulation]. Harefuah, 2006, Volume: 145, Issue:7 Topics: Administration, Topical; Adolescent; Animals; Child; Hair Preparations; Humans; Malathion; Pediculus	2006
Malathion for treatment of Pediculus humanus var capitis infestation. JAMA, 1982, Jun-11, Volume: 247, Issue:22 Topics: Administration, Topical; Adolescent; Adult; Child; Child, Preschool; Clinical Trials as Topic; Doubl	1982
Evidence for double resistance to permethrin and malathion in head lice. The British journal of dermatology, 1999, Volume: 141, Issue:3 Topics: Animals; Carbaryl; Child; DDT; Drug Resistance, Multiple; Humans; Insecticides; Lice Infestations; M	1999
Comparison of wet combing with malathion for treatment of head lice in the UK: a pragmatic randomised controlled trial. Lancet (London, England), 2000, Aug-12, Volume: 356, Issue:9229 Topics: Adolescent; Animals; Child; Child, Preschool; Humans; Insecticides; Lice Infestations; Malathion; Pe	2000

malathion and Scalp Dermatoses

Research Excerpts

Research

Studies (49)

Authors

Clinical Trials (1)

Trial Overview

Reviews

Trials

Other Studies

Article	Year
Head Lice: An Under-Recognized Tropical Problem. The American journal of tropical medicine and hygiene, 2017, Volume: 97, Issue:6 Topics: Animals; Humans; Insecticide Resistance; Insecticides; Ivermectin; Lice Infestations; Malathion; Ped	2017
Survey assessment on pediatricians' attitudes on head lice management. Italian journal of pediatrics, 2013, Oct-03, Volume: 39 Topics: Administration, Topical; Animals; Attitude of Health Personnel; Child; Child, Preschool; Female; Hea	2013
Scalp involvement by Sarcoptes scabiei var hominis resembling seborrhoeic dermatitis in two immunocompromised patients with systemic lupus erythematosus. The New Zealand medical journal, 2013, Aug-16, Volume: 126, Issue:1380 Topics: Adolescent; Adult; Animals; Diagnosis, Differential; Female; Humans; Immunocompromised Host; Insecti	2013
Head lice treatments: Searching for the path of least resistance. Journal of the American Academy of Dermatology, 2009, Volume: 61, Issue:2 Topics: Animals; Hexachlorocyclohexane; Humans; Incidence; Insecticide Resistance; Insecticides; Lice Infest	2009
Ivermectin versus malathion for head lice. The New England journal of medicine, 2010, Jun-24, Volume: 362, Issue:25 Topics: Animals; Child; Humans; Insecticides; Ivermectin; Leukemia; Lice Infestations; Malathion; Pediculus;	2010
Clinical response and safety of malathion shampoo for treatment of head lice in a primary school. Journal of the Medical Association of Thailand = Chotmaihet thangphaet, 2011, Volume: 94, Issue:4 Topics: Adolescent; Animals; Biomarkers; Child; Cholinesterases; Female; Follow-Up Studies; Humans; Insectic	2011
Head lice. The New England journal of medicine, 2002, 10-24, Volume: 347, Issue:17 Topics: Animals; Humans; Insecticides; Lice Infestations; Malathion; Pediculus; Scalp Dermatoses; United Sta	2002
Review of common therapeutic options in the United States for the treatment of pediculosis capitis. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2003, Jun-01, Volume: 36, Issue:11 Topics: Animals; Hexachlorocyclohexane; Humans; Insecticides; Ivermectin; Lice Infestations; Malathion; Pedi	2003
Head lice diagnosed in general practice in the West Midlands between 1993 and 2000: a survey using the General Practice Research Database. Communicable disease and public health, 2003, Volume: 6, Issue:2 Topics: Adolescent; Adult; Age Distribution; Aged; Animals; Antiparasitic Agents; Child; Child, Preschool; C	2003
Permethrin-resistant human head lice, Pediculus capitis, and their treatment. Archives of dermatology, 2003, Volume: 139, Issue:8 Topics: Animals; Child; Genotype; Humans; In Vitro Techniques; Insecticide Resistance; Insecticides; Lice In	2003
Head lice revisited: in vitro standardized tests and differences in malathion formulations. Archives of dermatology, 2004, Volume: 140, Issue:4 Topics: Animals; Drug Resistance, Microbial; Humans; In Vitro Techniques; Incidence; Lice Infestations; Mala	2004
High in vitro efficacy of Nyda L, a pediculicide containing dimeticone. Journal of the European Academy of Dermatology and Venereology : JEADV, 2007, Volume: 21, Issue:10 Topics: Animals; Dimethylpolysiloxanes; Hair Preparations; In Vitro Techniques; Insecticide Resistance; Inse	2007
Malathion for treatment of head lice. The Medical letter on drugs and therapeutics, 1983, Mar-18, Volume: 25, Issue:631 Topics: Administration, Topical; Adult; Child; Humans; Lice Infestations; Malathion; Scalp Dermatoses	1983
Pediculus humanus capitis in schoolchildren. Lancet (London, England), 1995, Mar-18, Volume: 345, Issue:8951 Topics: Child; Humans; Insecticides; Lice Infestations; Malathion; Pyrethrins; Scalp Dermatoses	1995
[First cases of resistance of Pediculus capitis Linné 1758 to malathion in France]. Presse medicale (Paris, France : 1983), 1995, Oct-21, Volume: 24, Issue:31 Topics: Child; Drug Resistance; Female; France; Humans; Insecticides; Lice Infestations; Malathion; Scalp De	1995
[Back again: the clothes louse (Pediculus humanus var. corporis)]. Nederlands tijdschrift voor geneeskunde, 1996, Sep-21, Volume: 140, Issue:38 Topics: Adult; Humans; Ill-Housed Persons; Insecticides; Lice Infestations; Malathion; Male; Scalp Dermatose	1996
Drugs for head lice. The Medical letter on drugs and therapeutics, 1997, Jan-17, Volume: 39, Issue:992 Topics: Administration, Oral; Drug Combinations; Drug Resistance; Hexachlorocyclohexane; Humans; Insecticide	1997
Head lice. Communicable disease report. CDR weekly, 1997, Oct-10, Volume: 7, Issue:41 Topics: Child; Female; Humans; Insecticides; Lice Infestations; Malathion; Male; Scalp Dermatoses	1997
[Swimming lice in child day care center--ABC on the treatment of lice infestations. An adequate therapy and contact tracing are successful factors]. Lakartidningen, 2000, Feb-09, Volume: 97, Issue:6 Topics: Animals; Child; Contact Tracing; Dermatologic Agents; Drug Resistance; Female; Hair Preparations; Hu	2000
Current treatments for scabies and pediculosis. Skin therapy letter, 1999, Volume: 5, Issue:1 Topics: Animals; Humans; Insecticides; Ivermectin; Lice Infestations; Malathion; Pediculus; Permethrin; Pyre	1999
Treatment of head lice. Lancet (London, England), 2000, Aug-12, Volume: 356, Issue:9229 Topics: Animals; Child; Humans; Insecticides; Lice Infestations; Malathion; Pediculus; Scalp Dermatoses	2000
Louse-y treatments. Health news (Waltham, Mass.), 2000, Volume: 6, Issue:10 Topics: Animals; Child; Humans; Insecticides; Lice Infestations; Malathion; Pediculus; Scalp Dermatoses	2000
Treatment of head lice. Lancet (London, England), 2000, Dec-09, Volume: 356, Issue:9246 Topics: Animals; Humans; Insecticides; Lice Infestations; Malathion; Pediculus; Scalp Dermatoses	2000
Treatment of head lice. Lancet (London, England), 2000, Dec-09, Volume: 356, Issue:9246 Topics: Adolescent; Animals; Child; Child, Preschool; Humans; Insecticides; Lice Infestations; Malathion; Pe	2000
Treatment of head lice. Lancet (London, England), 2000, Dec-09, Volume: 356, Issue:9246 Topics: Animals; Humans; Insecticides; Lice Infestations; Malathion; Pediculus; Scalp Dermatoses	2000
Treatment of head lice. Lancet (London, England), 2000, Dec-09, Volume: 356, Issue:9246 Topics: Adolescent; Animals; Child; Child, Preschool; Humans; Insecticides; Lice Infestations; Malathion; Pe	2000
Comparative efficacy of treatments for pediculosis capitis infestations: update 2000. Archives of dermatology, 2001, Volume: 137, Issue:3 Topics: Animals; Child; Hair Preparations; Humans; In Vitro Techniques; Insecticides; Lice Infestations; Mal	2001
Comparative in vitro pediculicidal efficacy of treatments in a resistant head lice population in the United States. Archives of dermatology, 2002, Volume: 138, Issue:2 Topics: Adult; Animals; Child; Hair Preparations; Hexachlorocyclohexane; Humans; In Vitro Techniques; Insect	2002