malathion and Acute Liver Injury, Drug-Induced
malathion has been researched along with Acute Liver Injury, Drug-Induced in 17 studies
Malathion: A wide spectrum aliphatic organophosphate insecticide widely used for both domestic and commercial agricultural purposes.
malathion : A racemate comprising equimolar amounts of (R) and (S)-malathion. It is a broad spectrum organophosphate proinsecticide used to control a wide range of pests including Coleoptera, Diptera, fruit flies, mosquitos and spider mites.
diethyl 2-[(dimethoxyphosphorothioyl)thio]succinate : A diester that is diethyl succinate in which position 2 is substituted by a (dimethoxyphosphorothioyl)thio group.
Research Excerpts
| Excerpt | Relevance | Reference |
|---|---|---|
| " Regarding the importance of liver on metabolic pathways regulation, in particular blood glucose homeostasis, we focused on liver inflammation and oxidative damages in a subchronic model of toxicity by malathion." | 7.80 | Association of inflammatory response and oxidative injury in the pathogenesis of liver steatosis and insulin resistance following subchronic exposure to malathion in rats. ( Abdelmoula, J; Ahmed, MB; Annabi, A; Belhadjhmida, N; Bouzid, K; Dhouib, IB; Fazaa, SE; Gharbi, N; Lamine, AJ; Lasram, MM, 2014) |
| " The present study is designed to investigate the preventive effect of N-acetylcysteine on malathion-induced hepatic injury and inflammation in rats." | 3.80 | Antioxidant and anti-inflammatory effects of N-acetylcysteine against malathion-induced liver damages and immunotoxicity in rats. ( Abdelmoula, J; Ahmed, MB; Annabi, A; Belhadjhmida, N; Bouzid, K; Dhouib, IB; El Fazaa, S; Gharbi, N; Lamine, AJ; Lasram, MM, 2014) |
| " Regarding the importance of liver on metabolic pathways regulation, in particular blood glucose homeostasis, we focused on liver inflammation and oxidative damages in a subchronic model of toxicity by malathion." | 3.80 | Association of inflammatory response and oxidative injury in the pathogenesis of liver steatosis and insulin resistance following subchronic exposure to malathion in rats. ( Abdelmoula, J; Ahmed, MB; Annabi, A; Belhadjhmida, N; Bouzid, K; Dhouib, IB; Fazaa, SE; Gharbi, N; Lamine, AJ; Lasram, MM, 2014) |
| "Malathion and LSEO were daily per orally (p." | 1.42 | Hepatoprotective and Renoprotective Effects of Lavender (Lavandula stoechas L.) Essential Oils Against Malathion-Induced Oxidative Stress in Young Male Mice. ( Gharbi, N; Jallouli, M; Marzouki, L; Selmi, S, 2015) |
| " Hereby, we analyzed the toxic effects of malathion on the histological structure of liver and biochemical parameters in male rats." | 1.42 | Malathion-induced hepatotoxicity in male Wistar rats: biochemical and histopathological studies. ( Belaïd-Nouira, Y; Ben Cheikh, H; Boughattas, S; Chargui, I; El Mabrouk, A; Flehi-Slim, I; Haouas, Z; Najjar, MF; Neffati, F, 2015) |
| "The malathion-treated rats also had significantly lower serum total protein and albumin levels, but the malathion plus vitamin-treated group did not differ from the control group in terms of these parameters." | 1.36 | Malathion-induced hepatotoxicity in rats: the effects of vitamins C and E. ( Demir, F; Durak, D; Kalender, S; Kalender, Y; Uzun, FG, 2010) |
| "Malathion was administered intragastrically in 1 ml corn oil containing 100 mg/kg Body Weight daily for 32 days." | 1.35 | Biochemical evaluation of hepatic damage in subchronic exposure to malathion in rats: effect on superoxide dismutase and catalase activities using native PAGE. ( El-Fazaa, S; Gharbi, N; Mornagui, B; Rezg, R, 2008) |
| " Toxic effects of human exposure may be influenced by their nutritional status." | 1.27 | Augmented hepatic susceptibility to malathion toxicity in rats on low-protein diets. ( Bulusu, S; Chakravarty, I, 1984) |
Research
Studies (17)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (23.53) | 18.7374 |
| 1990's | 2 (11.76) | 18.2507 |
| 2000's | 2 (11.76) | 29.6817 |
| 2010's | 9 (52.94) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
Authors
| Authors | Studies |
|---|---|
| Fourches, D | 1 |
| Barnes, JC | 1 |
| Day, NC | 1 |
| Bradley, P | 1 |
| Reed, JZ | 1 |
| Tropsha, A | 1 |
| Liu, Z | 1 |
| Shi, Q | 1 |
| Ding, D | 1 |
| Kelly, R | 1 |
| Fang, H | 1 |
| Tong, W | 1 |
| Lasram, MM | 2 |
| Lamine, AJ | 2 |
| Dhouib, IB | 2 |
| Bouzid, K | 2 |
| Annabi, A | 2 |
| Belhadjhmida, N | 2 |
| Ahmed, MB | 2 |
| El Fazaa, S | 1 |
| Abdelmoula, J | 2 |
| Gharbi, N | 4 |
| Fazaa, SE | 1 |
| Selmi, S | 1 |
| Jallouli, M | 1 |
| Marzouki, L | 1 |
| Zidan, Nel-H | 1 |
| Flehi-Slim, I | 1 |
| Chargui, I | 1 |
| Boughattas, S | 1 |
| El Mabrouk, A | 1 |
| Belaïd-Nouira, Y | 1 |
| Neffati, F | 1 |
| Najjar, MF | 1 |
| Haouas, Z | 1 |
| Ben Cheikh, H | 1 |
| Nikoukar, N | 1 |
| Kumar, EP | 1 |
| Suresh, B | 1 |
| Sualiman, SM | 1 |
| Venkataraman, BV | 1 |
| Rezg, R | 1 |
| Mornagui, B | 1 |
| El-Fazaa, S | 1 |
| Kalender, S | 1 |
| Uzun, FG | 1 |
| Durak, D | 1 |
| Demir, F | 1 |
| Kalender, Y | 1 |
| Aboul-Soud, MA | 1 |
| Al-Othman, AM | 1 |
| El-Desoky, GE | 1 |
| Al-Othman, ZA | 1 |
| Yusuf, K | 1 |
| Ahmad, J | 1 |
| Al-Khedhairy, AA | 1 |
| David, M | 1 |
| Shivakumar, HB | 1 |
| Ramesh, H | 1 |
| Marigoudar, SR | 1 |
| Naik, VR | 1 |
| Bulusu, S | 1 |
| Chakravarty, I | 1 |
| Keadtisuke, S | 1 |
| Dheranetra, W | 1 |
| Nakatsugawa, T | 1 |
| Fukuto, TR | 1 |
| Dikshith, TS | 1 |
| Srivastava, MK | 1 |
| Raizada, RB | 1 |
| Kumar, SN | 1 |
| Abdel-Rahman, MS | 1 |
| Lechner, DW | 1 |
| Klein, KM | 1 |
| Beskid, M | 1 |
| Klos, H | 1 |
| Suwala, Z | 1 |
| Szyszkowska, A | 1 |
| Wójcik, J | 1 |
Other Studies
17 other studies available for malathion and Acute Liver Injury, Drug-Induced
| Article | Year |
|---|---|
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLI | 2010 |
Translating clinical findings into knowledge in drug safety evaluation--drug induced liver injury prediction system (DILIps).
Topics: Animals; Anti-Infective Agents; Anti-Inflammatory Agents; Chemical and Drug Induced Liver Injury; Da | 2011 |
Antioxidant and anti-inflammatory effects of N-acetylcysteine against malathion-induced liver damages and immunotoxicity in rats.
Topics: Acetylcysteine; Animals; Anti-Inflammatory Agents; Antioxidants; Apoptosis; Biomarkers; Blotting, We | 2014 |
Association of inflammatory response and oxidative injury in the pathogenesis of liver steatosis and insulin resistance following subchronic exposure to malathion in rats.
Topics: Animals; Biomarkers; Blood Glucose; Chemical and Drug Induced Liver Injury; Cytokines; Fatty Liver; | 2014 |
Hepatoprotective and Renoprotective Effects of Lavender (Lavandula stoechas L.) Essential Oils Against Malathion-Induced Oxidative Stress in Young Male Mice.
Topics: Animals; Catalase; Chemical and Drug Induced Liver Injury; Glutathione Peroxidase; Hydrogen Peroxide | 2015 |
Hepato- and nephrotoxicity in male albino rats exposed to malathion and spinosad in stored wheat grains.
Topics: Animals; Chemical and Drug Induced Liver Injury; Drug Combinations; Edible Grain; Food Contamination | 2015 |
Malathion-induced hepatotoxicity in male Wistar rats: biochemical and histopathological studies.
Topics: Alanine Transaminase; Animals; Antioxidants; Aspartate Aminotransferases; Biomarkers; Chemical and D | 2015 |
BLOOD CHOLINESTERASE ACTIVITIES AFTER MALATHION POISONING IN LIVER INJURY.
Topics: Animals; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Cholinesterases; Insecticides | 1999 |
Biochemical evaluation of hepatic damage in subchronic exposure to malathion in rats: effect on superoxide dismutase and catalase activities using native PAGE.
Topics: Alanine Transaminase; Animals; Aspartate Aminotransferases; Butyrylcholinesterase; Catalase; Chemica | 2008 |
Malathion-induced hepatotoxicity in rats: the effects of vitamins C and E.
Topics: Administration, Oral; Animals; Antioxidants; Ascorbic Acid; Blood Chemical Analysis; Blood Platelets | 2010 |
Hepatoprotective effects of vitamin E/selenium against malathion-induced injuries on the antioxidant status and apoptosis-related gene expression in rats.
Topics: Acetylcholinesterase; Animals; Antioxidants; Apoptosis; Chemical and Drug Induced Liver Injury; Dose | 2011 |
Hepatotoxic potential of Malathion in the freshwater teleost, Cirrhinus mrigala (Hamilton).
Topics: Acetylcholine; Acetylcholinesterase; Adaptation, Physiological; Amino Acids; Animals; Chemical and D | 2007 |
Augmented hepatic susceptibility to malathion toxicity in rats on low-protein diets.
Topics: Alanine Transaminase; Animals; Aspartate Aminotransferases; Body Weight; Chemical and Drug Induced L | 1984 |
Liver damage induced in rats by malathion impurities.
Topics: Administration, Oral; Alanine Transaminase; Animals; Aspartate Aminotransferases; Blood Coagulation; | 1990 |
Interaction of hexachlorocyclohexane and malathion in male guinea pigs after repeated dermal application.
Topics: Acetylcholinesterase; Administration, Cutaneous; Animals; Body Weight; Chemical and Drug Induced Liv | 1987 |
Combination effect of carbaryl and malathion in rats.
Topics: Animals; Carbaryl; Chemical and Drug Induced Liver Injury; Drug Interactions; Female; Glucuronidase; | 1985 |
[Effect of malathion on the morphological structure and some histochemical reactions in rat's liver].
Topics: Acid Phosphatase; Animals; Chemical and Drug Induced Liver Injury; Esterases; Histocytochemistry; Li | 1973 |