malabaricone-a and Diabetes-Mellitus--Type-2

malabaricone-a has been researched along with Diabetes-Mellitus--Type-2* in 1 studies

Other Studies

1 other study(ies) available for malabaricone-a and Diabetes-Mellitus--Type-2

ArticleYear
Antidiabetic potential of phytochemicals isolated from the stem bark of Myristica fatua Houtt. var. magnifica (Bedd.) Sinclair.
    Bioorganic & medicinal chemistry, 2018, 07-23, Volume: 26, Issue:12

    Phytochemical investigation of the stem bark of Myristica fatua Houtt. led to the isolation of a new compound 1 (3-tridecanoylbenzoic acid), along with six known acylphenols (2-7). All the compounds displayed moderate inhibitory activity on α-amylase and significant activity on α-glucosidase; however malabaricone B (6) and C (7) were identified as potent α-glucosidase inhibitors with IC

    Topics: alpha-Glucosidases; Binding Sites; Cell Line; Cell Survival; Diabetes Mellitus, Type 2; Glycoside Hydrolase Inhibitors; Humans; Hypoglycemic Agents; Molecular Dynamics Simulation; Muscle Cells; Myristicaceae; Phytochemicals; Plant Bark; Plant Extracts; Plant Stems; Protein Structure, Tertiary; Resorcinols

2018