magnolol has been researched along with Disease Models, Animal in 32 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (3.13) | 18.2507 |
| 2000's | 6 (18.75) | 29.6817 |
| 2010's | 19 (59.38) | 24.3611 |
| 2020's | 6 (18.75) | 2.80 |
| Authors | Studies |
|---|---|
| Chen, T; Guo, X; Shou, L; Tao, T; Wei, M; Zheng, H | 1 |
| Kim, HJ; Kim, WK; Nam, JH; Nam, YR; NamKung, W; Phan, HTL; Woo, JH | 1 |
| Ali, H; Bibi, T; Khan, A; Khan, AU; Khan, S; Seo, EK; Shal, B | 1 |
| Gu, M; Guo, W; Huang, L; Liu, Y; Sun, H; Wang, N; Wu, Y; Xu, L; Yang, Y | 1 |
| Fu, Y; Hölscher, C; Jiang, Y; Wang, H; Xie, Z; Xu, J; Yang, Q; Zeng, H; Zhang, Z; Zhao, J | 1 |
| Fortunato, CRM; Gomes, KS; Grecco, SS; Lago, JHG; Oliveira, MA; Olivo, CR; Ponci, V; Prado, CM; Santana, FPR; Silva, RC; Tavares-de-Lima, W; Tibério, IFLC | 1 |
| Huang, F; Song, L; Zhang, RY | 1 |
| Bai, Y; Dai, G; Jing, W; Ju, W; Song, L; Xu, M; Zhang, W; Zhu, L | 1 |
| Hu, Z; Jiang, Z; Yang, B; Zhou, F | 1 |
| Bai, Y; Dai, G; Jing, W; Ju, W; Song, L; Song, S; Sun, H; Xu, M; Zhang, W; Zhang, Y | 1 |
| Li, LF; Ma, SP; Qu, R; Yang, J | 1 |
| Chio, CC; Kuo, JR; Lin, BS; Lin, KC; Wang, CC | 1 |
| Chen, G; Gong, H; Tang, W; Wang, J; Xiang, J; Zhao, J | 1 |
| Cao, W; Huang, L; Liu, Y; Liu, YQ; Ming, PH; Wang, ZY; Wu, YP; Yu, XJ; Zhang, B; Zhang, XD; Zhou, GB | 1 |
| Cho, IJ; Jang, EJ; Jegal, KH; Jung, JY; Kang, SH; Kim, SC; Kim, YW; Ku, SK; Lee, JH; Lee, JR; Moon, SY; Park, SJ; Zhao, RJ | 1 |
| Dejie, L; Naisheng, Z; Tiancheng, W; Wei, W; Xiaojing, S; Yongguo, C; Zhengtao, Y | 1 |
| Akae, H; Akagi, M; Fukuyama, Y; Hirashima, N; Kido, Y; Koseki, M; Matsui, N; Tanabe, S | 1 |
| Chan, MH; Chao, KT; Chen, ZA; Ee, TW; Hsiao, IT; Hsu, CH; Kung, MP; Lin, KJ; Weng, CC; Wey, SP; Yen, TC | 1 |
| Bae, KH; Chang, KC; Ha, YM; Jin, YC; Kang, SS; Kim, HJ; Kim, KJ; Kim, YM; Kim, YS; Lee, JH; Seo, HG; Yun, UJ | 1 |
| Ren, AM; Sun, LN; Wang, H; Yang, TC; Zhang, SW | 1 |
| Chung, YS; Kim, YC; Lee, BH; Shin, YK; Yin, HQ | 1 |
| Wang, HM; Zhang, SW | 1 |
| Cheng, PY; Ke, TH; Kung, CW; Peng, YJ; Tsai, YC; Wang, JJ; Yen, MH | 1 |
| Chan, MH; Chen, HH; Lin, SC | 1 |
| Deng, JM; Li, LF; Li, XM; Lu, J; Ma, SP; Qu, R; Xu, CL | 1 |
| Chang, AS; Liou, JP; Shih, KS; Tsai, CL; Wang, JH; Wang, KL; Wu, YW; Yang, CR | 1 |
| Cheng, QS; Gu, ZP; Han, Y; Jiang, T; Ke, CK; Li, XF; Ni, YF; Wang, J; Wang, WP; Yan, XL; Zhang, ZP; Zhu, YF | 1 |
| Cao, Y; Feng, X; Fu, Y; Li, F; Liang, D; Liu, B; Liu, Z; Yang, Z; Zhang, N; Zhang, X | 1 |
| Chan, MH; Chen, HH; Ko, CH; Lin, YR | 2 |
| Kong, LD; Li, JM; Li, YC; Pan, Y; Wang, CP; Wang, X; Xu, Q; Yi, LT | 1 |
| Chang, LC; Chen, CC; Ho, TF; Wang, JP | 1 |
32 other study(ies) available for magnolol and Disease Models, Animal
| Article | Year |
|---|---|
Magnolol attenuates the locomotor impairment, cognitive deficit, and neuroinflammation in Alzheimer's disease mice with brain insulin resistance via up-regulating miR-200c.
Topics: Alzheimer Disease; Animals; Antagomirs; Biphenyl Compounds; Brain; Disease Models, Animal; Insulin Resistance; Lignans; Locomotion; Male; Malondialdehyde; Mice; Morris Water Maze Test; Spatial Learning; Streptozocin | 2022 |
In-vitro and in-vivo anti-allergic effects of magnolol on allergic rhinitis via inhibition of ORAI1 and ANO1 channels.
Topics: Animals; Anoctamin-1; Anti-Allergic Agents; Biphenyl Compounds; Cell Line, Tumor; Cytokines; Disease Models, Animal; Dose-Response Relationship, Drug; Female; Flowers; HEK293 Cells; Humans; Lignans; Magnolia; Mice; Mice, Inbred BALB C; Neoplasm Proteins; ORAI1 Protein; Ovalbumin; Patch-Clamp Techniques; Rhinitis, Allergic | 2022 |
Magnolol prevented brain injury through the modulation of Nrf2-dependent oxidative stress and apoptosis in PLP-induced mouse model of multiple sclerosis.
Topics: Animals; Antioxidants; Apoptosis; Biphenyl Compounds; Brain Injuries; Caspase 3; CD8-Positive T-Lymphocytes; Disease Models, Animal; Encephalomyelitis, Autoimmune, Experimental; Female; Lignans; Mice; Molecular Docking Simulation; Multiple Sclerosis; NF-E2-Related Factor 2; Oxidative Stress | 2022 |
Magnolol limits NFκB-dependent inflammation by targeting PPARγ relieving retinal ischemia/reperfusion injury.
Topics: Animals; Anti-Inflammatory Agents; Disease Models, Animal; Eosine Yellowish-(YS); Glaucoma; Hematoxylin; Inflammation; Ischemia; Mice; NF-kappa B; NF-KappaB Inhibitor alpha; PPAR gamma; Reperfusion Injury; Retina | 2022 |
Magnolol alleviates Alzheimer's disease-like pathology in transgenic C. elegans by promoting microglia phagocytosis and the degradation of beta-amyloid through activation of PPAR-γ.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Animals, Genetically Modified; Apolipoproteins E; Biphenyl Compounds; Caenorhabditis elegans; Disease Models, Animal; Dose-Response Relationship, Drug; Humans; Inflammation; Lignans; Microglia; NF-kappa B; Phagocytosis; PPAR gamma | 2020 |
Biseugenol Exhibited Anti-Inflammatory and Anti-Asthmatic Effects in an Asthma Mouse Model of Mixed-Granulocytic Asthma.
Topics: Animals; Anti-Asthmatic Agents; Anti-Inflammatory Agents; Asthma; Biological Availability; Biphenyl Compounds; Computer Simulation; Disease Models, Animal; Granulocytes; Inflammation; Lignans; Linear Models; Male; Mice, Inbred BALB C; Phenyl Ethers; Respiratory Function Tests; Respiratory Hypersensitivity | 2020 |
Beneficial effect of magnolol on lupus nephritis in MRL/lpr mice by attenuating the NLRP3 inflammasome and NF‑κB signaling pathway: A mechanistic analysis.
Topics: Animals; Anti-Arrhythmia Agents; Antibodies, Antinuclear; Biopsy; Biphenyl Compounds; Cytokines; Disease Models, Animal; Female; Histocytochemistry; Inflammasomes; Inflammation Mediators; Lignans; Lupus Nephritis; Macrophages; Mice; Mice, Inbred MRL lpr; NF-kappa B; NLR Family, Pyrin Domain-Containing 3 Protein; Signal Transduction | 2017 |
Antidepressant effects of magnolol in a mouse model of depression induced by chronic corticosterone injection.
Topics: Animals; Antidepressive Agents; Behavior, Animal; Biphenyl Compounds; Brain-Derived Neurotrophic Factor; Corticosterone; Depression; Disease Models, Animal; Food Preferences; Gene Expression Regulation; Hippocampus; Hypothalamus; Injections; Lignans; Male; Mice; Mice, Inbred ICR; Norepinephrine; Pituitary-Adrenal System; RNA, Messenger; Serotonin; Sucrose | 2018 |
Magnolol exhibits anti-inflammatory and neuroprotective effects in a rat model of intracerebral haemorrhage.
Topics: Animals; Anti-Inflammatory Agents; Astrocytes; Biphenyl Compounds; Blood-Brain Barrier; Brain; Brain Edema; Brain Ischemia; Cerebral Hemorrhage; Cytokines; Disease Models, Animal; Inflammation; Lignans; Male; Neuroglia; Neuroprotective Agents; Rats; Rats, Sprague-Dawley; Stroke | 2019 |
Comparative pharmacokinetic study of four major bioactive components after oral administration of Zhi-Zi-Hou-Po decoction in normal and corticosterone-induced depressive rats.
Topics: Administration, Oral; Animals; Biphenyl Compounds; Corticosterone; Depression; Disease Models, Animal; Drugs, Chinese Herbal; Hesperidin; Iridoids; Lignans; Limit of Detection; Linear Models; Male; Rats; Rats, Sprague-Dawley; Reproducibility of Results | 2019 |
Magnolol treatment reversed the glial pathology in an unpredictable chronic mild stress-induced rat model of depression.
Topics: Animals; Antidepressive Agents; Behavior, Animal; Biphenyl Compounds; Depression; Disease Models, Animal; Dose-Response Relationship, Drug; Fluoxetine; Food Preferences; Glial Fibrillary Acidic Protein; Hippocampus; Lignans; Male; Motor Activity; Neuroglia; Prefrontal Cortex; Rats; Rats, Sprague-Dawley; RNA, Messenger; Stress, Psychological; Swimming | 2013 |
Resuscitation from experimental traumatic brain injury by magnolol therapy.
Topics: Animals; Apoptosis; Biphenyl Compounds; Brain Injuries; Disease Models, Animal; Free Radical Scavengers; Glycerol; Hippocampus; Hydroxybenzoates; Lignans; Male; Models, Animal; Neuroprotective Agents; Rats; Rats, Sprague-Dawley; Resuscitation; Transforming Growth Factor beta1 | 2013 |
Pharmacokinetic and pharmacodynamic studies of four major phytochemical components of Da-Cheng-Qi decoction to treat acute pancreatitis.
Topics: Animals; Anthraquinones; Apoptosis; Biphenyl Compounds; Cells, Cultured; Disease Models, Animal; Drugs, Chinese Herbal; Flavanones; Hesperidin; Lignans; Male; Necrosis; Pancreas; Pancreatitis, Acute Necrotizing; Phytotherapy; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species | 2013 |
The natural compound magnolol inhibits invasion and exhibits potential in human breast cancer therapy.
Topics: Animals; Antineoplastic Agents; Biological Products; Biphenyl Compounds; Breast Neoplasms; Cell Adhesion; Cell Line, Tumor; Cell Movement; Disease Models, Animal; Dose-Response Relationship, Drug; Female; Heterografts; Humans; Lignans; Matrix Metalloproteinase 9; Neoplasm Invasiveness; NF-kappa B; Signal Transduction; Tumor Burden | 2013 |
Combination of honokiol and magnolol inhibits hepatic steatosis through AMPK-SREBP-1 c pathway.
Topics: AMP-Activated Protein Kinases; Animals; Biphenyl Compounds; Cell Line; Diet, High-Fat; Disease Models, Animal; Drug Synergism; Drug Therapy, Combination; Enzyme Inhibitors; Fatty Liver; Hepatocytes; Humans; Lignans; Lipogenesis; Liver X Receptors; Male; Mice; Mice, Inbred C57BL; Orphan Nuclear Receptors; Signal Transduction; Sterol Regulatory Element Binding Protein 1 | 2015 |
Magnolol inhibits the inflammatory response in mouse mammary epithelial cells and a mouse mastitis model.
Topics: Animals; Biphenyl Compounds; Cells, Cultured; Disease Models, Animal; Dose-Response Relationship, Drug; Epithelial Cells; Female; Humans; Inflammation; Lignans; Male; Mammary Glands, Animal; Mastitis; Mice; Mice, Inbred BALB C | 2015 |
Magnolol Enhances Hippocampal Neurogenesis and Exerts Antidepressant-Like Effects in Olfactory Bulbectomized Mice.
Topics: Animals; Antidepressive Agents; Biphenyl Compounds; Depression; Disease Models, Animal; Hippocampus; Lignans; Male; Mice; Neurogenesis; Olfactory Bulb; Phosphorylation; Signal Transduction | 2016 |
Quantitative analysis of the therapeutic effect of magnolol on MPTP-induced mouse model of Parkinson's disease using in vivo 18F-9-fluoropropyl-(+)-dihydrotetrabenazine PET imaging.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Biphenyl Compounds; Corpus Striatum; Disease Models, Animal; Fluorine Radioisotopes; Humans; Lignans; Mice; Neurons; Parkinson Disease; Parkinson Disease, Secondary; Positron-Emission Tomography; Tetrabenazine; Vesicular Monoamine Transport Proteins | 2017 |
Anti-apoptotic effect of magnolol in myocardial ischemia and reperfusion injury requires extracellular signal-regulated kinase1/2 pathways in rat in vivo.
Topics: Animals; Apoptosis; Biphenyl Compounds; Caspase 3; Disease Models, Animal; Flavonoids; Heart; Lignans; Male; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Myocardial Infarction; Myocardial Reperfusion Injury; Plant Extracts; Proto-Oncogene Proteins c-bcl-2; Rats; Rats, Sprague-Dawley; Signal Transduction | 2008 |
Magnolol attenuates sepsis-induced gastrointestinal dysmotility in rats by modulating inflammatory mediators.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Biphenyl Compounds; Chemokine CCL2; Disease Models, Animal; Gastrointestinal Diseases; Gastrointestinal Motility; Ileum; Inflammation Mediators; Interleukin-10; Lignans; Lipopolysaccharides; Male; Malondialdehyde; NF-kappa B; Nitric Oxide Synthase Type II; Rats; Rats, Wistar; RNA, Messenger; Sepsis; Superoxide Dismutase; Tumor Necrosis Factor-alpha | 2008 |
Honokiol reverses alcoholic fatty liver by inhibiting the maturation of sterol regulatory element binding protein-1c and the expression of its downstream lipogenesis genes.
Topics: Active Transport, Cell Nucleus; Animals; Biphenyl Compounds; Cell Line, Tumor; Cytoprotection; Disease Models, Animal; Dose-Response Relationship, Drug; Ethanol; fas Receptor; Fatty Acids; Fatty Liver, Alcoholic; Genes, Reporter; Glutathione; Lignans; Lipogenesis; Liver; Male; Promoter Regions, Genetic; Protective Agents; Rats; Rats, Wistar; Sterol Regulatory Element Binding Protein 1; Transcription, Genetic; Transfection; Triglycerides; Tumor Necrosis Factor-alpha | 2009 |
[The intervention effects of different drugs on dendritic cells in acute pancreatitis in mouse].
Topics: Amylases; Animals; Biphenyl Compounds; Ceruletide; Dendritic Cells; Disease Models, Animal; Interferon-gamma; Interleukin-10; Lignans; Mice; Mice, Inbred BALB C; Octreotide; Pancreas; Pancreatitis | 2010 |
Beneficial effects of magnolol in a rodent model of endotoxin shock.
Topics: Animals; Antithrombin III; Biphenyl Compounds; Blood Pressure; Disease Models, Animal; Gene Expression Regulation, Enzymologic; Heart Rate; Kidney; Lignans; Lipopolysaccharides; Liver; Lung; Male; Nitrates; Nitric Oxide Synthase Type II; Nitrites; Peptide Hydrolases; Rats; Rats, Wistar; Shock, Septic; Superoxides; Survival Rate; Tumor Necrosis Factor-alpha | 2010 |
Protective and restorative effects of magnolol on neurotoxicity in mice with 6-hydroxydopamine-induced hemiparkinsonism.
Topics: Animals; Biphenyl Compounds; Corpus Striatum; Disease Models, Animal; Drug Administration Schedule; Lignans; Male; Mice; Neuroprotective Agents; Oxidopamine; Parkinsonian Disorders; Tyrosine 3-Monooxygenase | 2011 |
Antidepressant-like effect of magnolol on BDNF up-regulation and serotonergic system activity in unpredictable chronic mild stress treated rats.
Topics: Animals; Antidepressive Agents; Biphenyl Compounds; Brain-Derived Neurotrophic Factor; Chromatography, High Pressure Liquid; Disease Models, Animal; Exploratory Behavior; Food Preferences; Hippocampus; Immunohistochemistry; Lignans; Magnolia; Male; Motor Activity; Phytotherapy; Prefrontal Cortex; Rats; Rats, Sprague-Dawley; Stress, Physiological; Sucrose | 2012 |
Anti-arthritic effects of magnolol in human interleukin 1β-stimulated fibroblast-like synoviocytes and in a rat arthritis model.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis; Biphenyl Compounds; Cytokines; Disease Models, Animal; Fibroblasts; Humans; Inflammation Mediators; Interleukin-1beta; Lignans; Matrix Metalloproteinases; Rats; Synovial Membrane; Treatment Outcome | 2012 |
Protective effect of magnolol on lipopolysaccharide-induced acute lung injury in mice.
Topics: Acute Lung Injury; Animals; Anti-Inflammatory Agents, Non-Steroidal; Biphenyl Compounds; Bronchoalveolar Lavage Fluid; Cyclooxygenase 2; Disease Models, Animal; Edema; Interleukin-1beta; Lignans; Lipopolysaccharides; Lung; Male; Mice; Mice, Inbred BALB C; Peroxidase; Respiratory Distress Syndrome; Tumor Necrosis Factor-alpha | 2012 |
Magnolol inhibits lipopolysaccharide-induced inflammatory response by interfering with TLR4 mediated NF-κB and MAPKs signaling pathways.
Topics: Animals; Anti-Inflammatory Agents; Biphenyl Compounds; Cell Survival; Cells, Cultured; Cytokines; Disease Models, Animal; Dose-Response Relationship, Drug; Gene Expression Regulation; HEK293 Cells; Humans; Inflammation; Interleukin-8; Lignans; Lipopolysaccharides; MAP Kinase Signaling System; Mice; NF-kappa B; Signal Transduction; Toll-Like Receptor 4; Transfection | 2013 |
Differential inhibitory effects of honokiol and magnolol on excitatory amino acid-evoked cation signals and NMDA-induced seizures.
Topics: Analysis of Variance; Animals; Anti-Anxiety Agents; Biphenyl Compounds; Calcium; Cells, Cultured; Cerebellum; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Interactions; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Ion Channels; Lignans; Mice; N-Methylaspartate; Neurons; Platelet Aggregation Inhibitors; Potassium Chloride; Quinoxalines; Rats; Rats, Sprague-Dawley; Seizures; Sodium | 2005 |
Effects of honokiol and magnolol on acute and inflammatory pain models in mice.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Biphenyl Compounds; Central Nervous System Depressants; Disease Models, Animal; Drug Evaluation, Preclinical; Fixatives; Formaldehyde; Inflammation; Lignans; Lumbosacral Region; Magnolia; Memory; Mice; Pain; Posterior Horn Cells; Proto-Oncogene Proteins c-fos | 2007 |
Antidepressant-like effects of the mixture of honokiol and magnolol from the barks of Magnolia officinalis in stressed rodents.
Topics: Animals; Antidepressive Agents; Behavior, Animal; Biphenyl Compounds; Corticosterone; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Therapy, Combination; Exploratory Behavior; Hindlimb Suspension; Hydroxyindoleacetic Acid; Lignans; Magnolia; Male; Mice; Mice, Inbred ICR; Phytotherapy; Rats; Rats, Wistar; Serotonin; Stress, Physiological; Swimming | 2008 |
Anti-inflammatory effect of magnolol, isolated from Magnolia officinalis, on A23187-induced pleurisy in mice.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arachidonic Acid; Biphenyl Compounds; Body Fluids; Calcimycin; Dinoprostone; Disease Models, Animal; Leukotriene B4; Lignans; Mice; Mice, Inbred ICR; Plant Extracts; Pleura; Pleurisy; Proteins; Rats; Rats, Sprague-Dawley | 1995 |