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mafenide and Infection, Wound

mafenide has been researched along with Infection, Wound in 28 studies

Mafenide: A sulfonamide that inhibits the enzyme CARBONIC ANHYDRASE and is used as a topical anti-bacterial agent, especially in burn therapy.

Research Excerpts

ExcerptRelevanceReference
"The effect of daily treatment with three current topical antibacterial agents and four experimental formulations of chlorhexidine was evaluated after 1 week in rats with full thickness burns."3.67Comparison of standard and chlorhexidine-derivative topical antibacterial agents on the infected burned rat wound. ( Coderre, S; Germann, E; Gillespie, K; Henry, D; Roberts, FJ; Snelling, CF, 1988)
" After 156 hr of therapy with the medicated dosage forms, the previously infected areas did not demonstrate the presence of Pseudomonas."1.25Inhibition of Pseudomonas burn wound infection by mafenide dry foam. ( Catania, PN; King, JC, 1975)

Research

Studies (28)

TimeframeStudies, this research(%)All Research%
pre-199024 (85.71)18.7374
1990's1 (3.57)18.2507
2000's3 (10.71)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Barillo, DJ1
Brown, TL1
BRINKLEY, FB1
BAILEY, JA1
MENDELSON, JA1
Martineau, L1
Dosch, HM1
Pruitt, BA1
Munster, AM1
Buehler, PK1
Reading, GP1
Jacoby, FG1
Harrison, HN1
Hartford, CE1
Nolan, WB1
Richards, RM1
Mahlangu, GN1
Pegg, SP2
MacMillan, BG2
Rode, H1
de Wet, PM1
Davies, MR1
Cywes, S1
Salisbury, RE1
Bevin, AG1
Steinkraus, GE1
Enterline, DS1
Masterton, JP1
Ramsay, K1
Meldrum, L1
Laundy, M1
Robson, MC1
Moncrief, JA1
Ley, R1
Catania, PN1
King, JC1
Fernando, J1
Shuck, JM1
Thorne, LW1
Cooper, CG1
Stefanides, MM1
Copeland, CE1
Kominos, SD1
Yee, RB1
Vistnes, LM1
Schmitt, EE1
Ksander, GA1
Rose, EH1
Balkenhol, WJ1
Coleman, CL1
Elizarov, MN1
Garkavi, AV1
Komissarova, AL1
Gillett, AP1
Snelling, CF1
Roberts, FJ1
Germann, E1
Gillespie, K1
Coderre, S1
Henry, D1

Reviews

4 reviews available for mafenide and Infection, Wound

ArticleYear
Using mafenide acetate in acute and chronic wounds.
    Ostomy/wound management, 2002, Volume: Suppl

    Topics: Anti-Infective Agents, Local; Blast Injuries; Fasciitis, Necrotizing; Fractures, Open; History, 20th

2002
Dressings for burn injury in a military conflict--change of practice based on current evidence.
    Journal of the Royal Army Medical Corps, 2002, Volume: 148, Issue:3

    Topics: Anti-Infective Agents, Local; Burns; Cerium; Humans; Mafenide; Occlusive Dressings; Ointments; Silve

2002
Acute management of thermal injury.
    Annals of plastic surgery, 1981, Volume: 7, Issue:3

    Topics: Anti-Bacterial Agents; Bandages; Biological Dressings; Burns; Debridement; Fluid Therapy; Humans; Ma

1981
Therapy for burn wound infection.
    Journal of clinical and hospital pharmacy, 1981, Volume: 6, Issue:4

    Topics: Administration, Topical; Anti-Bacterial Agents; Burns; Cerium; Gentamicins; Humans; Mafenide; Povido

1981

Trials

1 trial available for mafenide and Infection, Wound

ArticleYear
[Treatment of suppurative-necrotic decubitus ulcers in patients with spinal injuries by using alginate coating teralgim and algimaf].
    Sovetskaia meditsina, 1991, Issue:3

    Topics: Adult; Alginates; Amylases; Drug Combinations; Humans; Mafenide; Middle Aged; Necrosis; Occlusive Dr

1991

Other Studies

23 other studies available for mafenide and Infection, Wound

ArticleYear
COMPARATIVE DURATION OF THE ANTIBACTERIAL EFFECT OF TOPICAL PENICILLIN AND MAFENIDE ON EXPERIMENTAL WOUNDS.
    The Journal of laboratory and clinical medicine, 1963, Volume: 62

    Topics: Animals; Anti-Bacterial Agents; Goats; Mafenide; Penicillins; Pharmacology; Research; Staphylococcal

1963
Management of bioburden with a burn gel that targets nociceptors.
    Journal of wound care, 2007, Volume: 16, Issue:4

    Topics: Acetic Acid; Animals; Anti-Infective Agents, Local; Burns; Citric Acid; Drug Combinations; Gels; Maf

2007
The diagnosis and treatment of infection in the burn patient.
    Burns, including thermal injury, 1984, Volume: 11, Issue:2

    Topics: Antifungal Agents; Bacterial Infections; Biopsy; Burns; Debridement; Humans; Mafenide; Mycoses; Neut

1984
The early management of thermal burns.
    Surgery, 1980, Volume: 87, Issue:1

    Topics: Administration, Topical; Airway Obstruction; Anti-Bacterial Agents; Anticoagulants; Bronchitis; Burn

1980
The "Sulfamylon sandwich"--a laminated mafenide-saline dressing.
    Annals of plastic surgery, 1980, Volume: 5, Issue:2

    Topics: Administration, Topical; Bandages; Burns; Humans; Mafenide; Skin Transplantation; Sodium Chloride; S

1980
The bequests of Moncrief and Moyer: an appraisal of topical therapy of burns- 1981 American Burn Association Presidential Address.
    The Journal of trauma, 1981, Volume: 21, Issue:10

    Topics: Administration, Topical; Adolescent; Adult; Aged; Anti-Infective Agents; Burns; Child; Child, Presch

1981
The role of drugs in management of burns.
    Drugs, 1982, Volume: 24, Issue:3

    Topics: Administration, Topical; Anti-Bacterial Agents; Burns; Candidiasis; Gentamicins; Humans; Mafenide; P

1982
The control of burn wound sepsis.
    Intensive care medicine, 1981, Volume: 7, Issue:2

    Topics: Burns; Gentamicins; Humans; Mafenide; Nitrofurazone; Povidone-Iodine; Sepsis; Silver Nitrate; Silver

1981
An experimental evaluation of the germicidal efficacy of three topical antimicrobial agents in burns.
    Progress in pediatric surgery, 1981, Volume: 14

    Topics: Administration, Topical; Animals; Burns; Disease Models, Animal; Mafenide; Male; Povidone; Povidone-

1981
Burn wound sepsis: effect of delayed treatment with topical chemotherapy on survival.
    The Journal of trauma, 1980, Volume: 20, Issue:2

    Topics: Administration, Topical; Animals; Burns; Cerium; Disease Models, Animal; Mafenide; Pseudomonas Infec

1980
Infections following burn injury.
    The Surgical clinics of North America, 1980, Volume: 60, Issue:1

    Topics: Burns; Gentamicins; Humans; Mafenide; Nitrofurazone; Povidone-Iodine; Silver Nitrate; Silver Sulfadi

1980
Progress in burns care.
    The Australian and New Zealand journal of surgery, 1979, Volume: 49, Issue:4

    Topics: Bacterial Infections; Baths; Burns; Humans; Mafenide; Silver Sulfadiazine; Wound Infection

1979
Clinical comparison of maphenide and silver sulphadiazine.
    Scandinavian journal of plastic and reconstructive surgery, 1979, Volume: 13, Issue:1

    Topics: Adolescent; Adult; Aged; Anti-Bacterial Agents; Bacterial Infections; Burns; Child; Drug Evaluation;

1979
Bacterial control in the burn wound.
    Clinics in plastic surgery, 1979, Volume: 6, Issue:4

    Topics: Burns; Gentamicins; Humans; Mafenide; Povidone-Iodine; Silver Nitrate; Silver Sulfadiazine; Wound In

1979
Topical therapy for control of bacteria in the burn wound.
    World journal of surgery, 1978, Volume: 2, Issue:2

    Topics: Administration, Topical; Anti-Bacterial Agents; Bacterial Infections; Burns; Gentamicins; Humans; Ma

1978
[Local treatment of burns. Panoplie and choice of therapies (author's transl)].
    Acta chirurgica Belgica, 1975, Volume: 74, Issue:5

    Topics: Anti-Bacterial Agents; Anti-Infective Agents, Local; Bandages; Baths; Debridement; Humans; Mafenide;

1975
Inhibition of Pseudomonas burn wound infection by mafenide dry foam.
    Journal of pharmaceutical sciences, 1975, Volume: 64, Issue:2

    Topics: Administration, Topical; Animals; Burns; Fluorescence; Guinea Pigs; Mafenide; Male; Ointments; Pseud

1975
Burn wound management.
    The Ceylon medical journal, 1976, Volume: 21, Issue:1

    Topics: Burns; Gentamicins; Humans; Mafenide; Silver Nitrate; Silver Sulfadiazine; Wound Infection

1976
Mafenide acetate solution dressings: an adjunct in burn wound care.
    The Journal of trauma, 1975, Volume: 15, Issue:7

    Topics: Adolescent; Adult; Bandages; Burns; Child; Child, Preschool; Debridement; Female; Humans; Infant; Ma

1975
In vitro penetration of topical antiseptics through eschar of burn patients.
    Annals of surgery, 1976, Volume: 183, Issue:4

    Topics: Anti-Infective Agents, Local; Bacterial Infections; Burns; Candidiasis; Gentamicins; Humans; In Vitr

1976
Evaluation of a prototype therapeutic system for prolonged, continuous topical delivery of homosulfanilamide in the management of Pseudomonas burn wound sepsis.
    Surgery, 1976, Volume: 79, Issue:6

    Topics: Administration, Topical; Animals; Bandages; Burns; Disease Models, Animal; Mafenide; Male; Ointments

1976
Antibiotic prophylaxis and therapy in burns.
    The Journal of hospital infection, 1985, Volume: 6 Suppl B

    Topics: Administration, Topical; Anti-Bacterial Agents; Burns; Chlorhexidine; Gentamicins; Humans; Kinetics;

1985
Comparison of standard and chlorhexidine-derivative topical antibacterial agents on the infected burned rat wound.
    Burns, including thermal injury, 1988, Volume: 14, Issue:2

    Topics: Administration, Topical; Animals; Anti-Bacterial Agents; Burns; Chlorhexidine; Drug Therapy, Combina

1988