Page last updated: 2024-09-04

m 8218 and Inflammation

m 8218 has been researched along with Inflammation in 9 studies

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's7 (77.78)24.3611
2020's2 (22.22)2.80

Authors

AuthorsStudies
Jing, G; Kong, Q; Ming, T; Song, X; Wu, X; Yuan, M1
Chen, L; Tan, HB; Zhao, Q1
Leng, Y; Liu, HM; Meng, QT; Song, XM; Wang, EY; Wu, XJ; Xia, ZY; Zhan, LY; Zhao, B1
Liu, QS; Wang, YL; Xiao, F; Yuan, QH; Zhan, J; Zhang, ZZ; Zheng, F1
Ailing, Y; Hongyu, X; Liwu, Z; Qingting, W; Xiaoling, S; Xin, L1
Cao, HJ; Diao, YG; Sun, YJ; Zhang, TZ; Zhou, J1
Cai, W; Su, Z1
Chen, C; Chen, Y; He, J; Huang, C; Zhang, Y1
Cai, DS; Jin, BB; Jin, Z; Pei, L1

Trials

1 trial(s) available for m 8218 and Inflammation

ArticleYear
Penehyclidine hydrochloride on postoperatively cognitive function.
    Medical hypotheses, 2019, Volume: 129

    Topics: Aged; Anesthesia, General; Atropine; Cholinergic Antagonists; Cognition; Cognitive Dysfunction; Cytokines; Delirium; Female; Humans; Incidence; Inflammation; Lung Neoplasms; Male; Mental Status and Dementia Tests; Postoperative Complications; Postoperative Period; Quinuclidines; Thoracoscopy; Treatment Outcome

2019

Other Studies

8 other study(ies) available for m 8218 and Inflammation

ArticleYear
Tumor necrosis factor α‑induced protein 8‑like 2 contributes to penehyclidine hydrochloride pretreatment against lipopolysaccharide‑induced acute lung injury in a mouse model.
    Molecular medicine reports, 2021, Volume: 24, Issue:5

    Topics: Acute Lung Injury; Animals; Apoptosis; Bronchoalveolar Lavage Fluid; Disease Models, Animal; Inflammation; Intracellular Signaling Peptides and Proteins; JNK Mitogen-Activated Protein Kinases; Lipopolysaccharides; Lung; Male; MAP Kinase Signaling System; Mice; Mice, Inbred BALB C; NF-kappa B; Quinuclidines; Transcription Factor RelA; Tumor Necrosis Factor-alpha

2021
Penehyclidine hydrochloride suppresses inflammation response and reduces podocyte injury in diabetic nephropathy by targeting fibrinogen-like protein 2.
    International immunopharmacology, 2022, Volume: 107

    Topics: Animals; Caspase 1; Diabetes Mellitus; Diabetic Nephropathies; Female; Fibrinogen; Humans; Inflammation; Male; NF-kappa B; NLR Family, Pyrin Domain-Containing 3 Protein; Podocytes; Quinuclidines; Rats; Toll-Like Receptor 4

2022
Penehyclidine hydrochloride inhibits TLR4 signaling and inflammation, and attenuates blunt chest trauma and hemorrhagic shock-induced acute lung injury in rats.
    Molecular medicine reports, 2018, Volume: 17, Issue:5

    Topics: Acute Lung Injury; Animals; Inflammation; Male; MAP Kinase Signaling System; Quinuclidines; Rats; Rats, Sprague-Dawley; Shock, Hemorrhagic; Thorax; Toll-Like Receptor 4; Wounds, Nonpenetrating

2018
Penehyclidine Hydrochloride Decreases Pulmonary Microvascular Endothelial Inflammatory Injury Through a Beta-Arrestin-1-Dependent Mechanism.
    Inflammation, 2018, Volume: 41, Issue:5

    Topics: beta-Arrestin 1; Cells, Cultured; Endothelial Cells; Humans; Inflammation; Lipopolysaccharides; Lung Injury; Microvessels; NF-kappa B; Quinuclidines; Up-Regulation

2018
Penehyclidine hydrochloride attenuates the cerebral injury in a rat model of cardiopulmonary bypass.
    Canadian journal of physiology and pharmacology, 2013, Volume: 91, Issue:7

    Topics: Animals; Apoptosis; Brain Injuries; Cardiopulmonary Bypass; Caspase 3; Cerebrum; Female; Hemodynamics; Hippocampus; Inflammation; Interleukin-10; Male; Matrix Metalloproteinase 9; p38 Mitogen-Activated Protein Kinases; Phosphopyruvate Hydratase; Phosphorylation; Proto-Oncogene Proteins c-bcl-2; Quinuclidines; Rats; Rats, Sprague-Dawley; RNA, Messenger; S100 Calcium Binding Protein beta Subunit

2013
Protective effect of penehvclidine hvdrochloride on ischemia-reperfusion injury in rats.
    Asian Pacific journal of tropical medicine, 2014, Volume: 7, Issue:1

    Topics: Animals; Cytokines; Female; Inflammation; Kidney; Oxidative Stress; Protective Agents; Quinuclidines; Random Allocation; Rats; Rats, Sprague-Dawley; Rats, Wistar; Reperfusion Injury

2014
Penehyclidine hydrochloride inhibits the LPS-induced inflammatory response in microglia.
    The Journal of surgical research, 2014, May-01, Volume: 188, Issue:1

    Topics: Animals; Cell Survival; Cells, Cultured; Dinoprostone; Drug Evaluation, Preclinical; Inflammation; Inflammation Mediators; Interleukin-1beta; Lipopolysaccharides; MAP Kinase Signaling System; Microglia; NF-kappa B; Nitric Oxide; Nitric Oxide Synthase Type II; Quinuclidines; Rats; Rats, Sprague-Dawley; Tumor Necrosis Factor-alpha

2014
Protective effects of penehyclidine hydrochloride on liver injury in a rat cardiopulmonary bypass model.
    European journal of anaesthesiology, 2010, Volume: 27, Issue:9

    Topics: Alanine Transaminase; Anesthesiology; Animals; Aspartate Aminotransferases; Cardiopulmonary Bypass; Femoral Artery; Heart Rate; Inflammation; Liver; Male; Microscopy, Electron; Postoperative Period; Quinuclidines; Rats; Rats, Sprague-Dawley; Ultrasonography

2010