m 8218 has been researched along with Disease Models, Animal in 17 studies
*Disease Models, Animal: Naturally-occurring or experimentally-induced animal diseases with pathological processes analogous to human diseases. [MeSH]
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (11.76) | 29.6817 |
| 2010's | 11 (64.71) | 24.3611 |
| 2020's | 4 (23.53) | 2.80 |
| Authors | Studies |
|---|---|
| Jing, G; Kong, Q; Ming, T; Song, X; Wu, X; Yuan, M | 1 |
| Bai, LQ; Li, WQ; Liu, QW; Wang, BZ; Yang, XY; Zhou, H | 1 |
| Ma, C; Wang, C; Wang, P; Zhao, H | 1 |
| Feng, Z; Kang, Y; Li, Y; Wen, H; Zheng, J; Zhu, J | 1 |
| Chang, Y; Li, Y; Liu, Z; Yu, J; Yu, L | 1 |
| Ma, J; Yang, Y; Zhao, L | 1 |
| Gao, Y; Lin, D; Ma, J; Tan, H; Wang, Y | 1 |
| Han, L; Liao, Z; Shi, T; Tong, R; Xiao, H | 1 |
| Chen, K; Li, JJ; Wang, YL; Wang, YP; Xiao, F; Zhan, J; Zhang, ZZ | 1 |
| Chen, Y; Liu, L; Mo, LQ; Mou, M; Ren, CH; Wu, GM; Zhou, J | 1 |
| Cao, HJ; Chen, KY; Ge, J; Pei, L; Yu, DM; Zhang, TZ; Zhou, J | 1 |
| Lin, D; Ma, J; Wang, Z; Xue, Y | 1 |
| Shu, Y; Yang, Y; Zhang, P | 1 |
| Dong, CM; Shi, H | 1 |
| Li, SL; Ma, ZF; Ouyang, YH; Song, W; Zhao, N | 1 |
| Kang, YQ; Leng, YF; Wang, T; Xue, X; Zhang, Y | 1 |
| Jia, BH; Lei, LR; Wang, YL | 1 |
17 other study(ies) available for m 8218 and Disease Models, Animal
| Article | Year |
|---|---|
Tumor necrosis factor α‑induced protein 8‑like 2 contributes to penehyclidine hydrochloride pretreatment against lipopolysaccharide‑induced acute lung injury in a mouse model.
Topics: Acute Lung Injury; Animals; Apoptosis; Bronchoalveolar Lavage Fluid; Disease Models, Animal; Inflammation; Intracellular Signaling Peptides and Proteins; JNK Mitogen-Activated Protein Kinases; Lipopolysaccharides; Lung; Male; MAP Kinase Signaling System; Mice; Mice, Inbred BALB C; NF-kappa B; Quinuclidines; Transcription Factor RelA; Tumor Necrosis Factor-alpha | 2021 |
Effects of penehyclidine hydrochloride on myocardial ischaemia-reperfusion injury in rats by inhibiting TLR4/MyD88/NF-κB pathway via miR-199a-3p.
Topics: Animals; Disease Models, Animal; MicroRNAs; Myeloid Differentiation Factor 88; Myocardial Reperfusion Injury; NF-kappa B; Rats; Toll-Like Receptor 4 | 2022 |
Smoking Attenuates Efficacy of Penehyclidine Hydrochloride in Acute Respiratory Distress Syndrome Induced by Lipopolysaccharide in Rats.
Topics: Animals; Blood Gas Analysis; Cigarette Smoking; Disease Models, Animal; JNK Mitogen-Activated Protein Kinases; Lipopolysaccharides; Lung; Male; MAP Kinase Signaling System; Mitogen-Activated Protein Kinases; p38 Mitogen-Activated Protein Kinases; Quinuclidines; Rats; Rats, Sprague-Dawley; Respiratory Distress Syndrome; Signal Transduction; Treatment Outcome | 2019 |
Prevention of renal ischemia and reperfusion injury by penehyclidine hydrochloride through autophagy activation.
Topics: Adenine; Alanine Transaminase; Animals; Apoptosis; Aspartate Aminotransferases; Autophagy; Beclin-1; Caspase 3; Cell Proliferation; Disease Models, Animal; Ischemia; Kidney; Male; Quinuclidines; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Sirolimus | 2020 |
Penehyclidine hydrochloride inhibits renal ischemia/reperfusion-induced acute lung injury by activating the Nrf2 pathway.
Topics: Acute Lung Injury; Animals; Apoptosis; Disease Models, Animal; Gene Knockout Techniques; Humans; Kidney; Kidney Diseases; Lung; Macrophages, Alveolar; Male; NF-E2-Related Factor 2; Oxidative Stress; Quassins; Quinuclidines; Rats; Rats, Transgenic; Reactive Oxygen Species; Reperfusion Injury; Signal Transduction; tert-Butylhydroperoxide | 2020 |
Penehyclidine hydrochloride preconditioning provides cardiac protection in a rat model of myocardial ischemia/reperfusion injury via the mechanism of mitochondrial dynamics mechanism.
Topics: Adenosine Triphosphate; Animals; Apoptosis; Cardiotonic Agents; Disease Models, Animal; Gene Expression Regulation; Heart; Ischemic Preconditioning; Male; Mitochondria; Mitochondrial Dynamics; Myocardial Reperfusion Injury; Oxidative Stress; Quinuclidines; Rats; Rats, Wistar; RNA, Messenger | 2017 |
Penehyclidine hydrochloride preconditioning provides pulmonary and systemic protection in a rat model of lung ischaemia reperfusion injury.
Topics: Animals; Apoptosis; Disease Models, Animal; Dose-Response Relationship, Drug; Gene Expression Regulation; Inflammation Mediators; Ischemic Preconditioning; Lung; Male; NF-kappa B; Oxidative Stress; Quinuclidines; Rats; Rats, Sprague-Dawley; Reperfusion Injury | 2018 |
Mechanism of penehyclidine hydrochloride on a dysmenorrhea rat model.
Topics: Animals; Behavior, Animal; Calcium; Disease Models, Animal; Dysmenorrhea; Estradiol; Female; Oxytocin; Pain; Quinuclidines; Rats, Sprague-Dawley; Receptor, Muscarinic M3; Toll-Like Receptor 3; Toll-Like Receptor 4; Uterus | 2019 |
Penehyclidine hydrochloride decreases pulmonary microvascular permeability by upregulating beta arrestins in a murine cecal ligation and puncture model.
Topics: Acute Lung Injury; Animals; Arrestins; beta-Arrestins; Capillary Permeability; Cecum; Cholinergic Antagonists; Disease Models, Animal; Female; Ligation; Lung; Mice, Inbred Strains; Microcirculation; NF-kappa B; Pulmonary Circulation; Quinuclidines; Random Allocation; Up-Regulation; Wounds, Stab | 2015 |
Penehyclidine hydrochloride postconditioning on lipopolysaccharide-induced acute lung injury by inhibition of inflammatory factors in a rodent model.
Topics: Acute Lung Injury; Animals; Bronchoalveolar Lavage Fluid; Disease Models, Animal; Drug Evaluation, Preclinical; Interleukin-6; Lipopolysaccharides; Lung; Male; NF-kappa B; Peroxidase; Pulmonary Gas Exchange; Quinuclidines; Rats, Sprague-Dawley; Sepsis; Tumor Necrosis Factor-alpha | 2015 |
Protective effect of penehyclidine hydrochloride on lipopolysaccharide-induced acute kidney injury in rat.
Topics: Acute Kidney Injury; Animals; Blood Urea Nitrogen; Creatinine; Cytokines; Disease Models, Animal; Kidney; Lipopolysaccharides; Male; Occludin; Protective Agents; Quinuclidines; Rats; Zonula Occludens-1 Protein | 2015 |
Penehyclidine Hydrochloride Preconditioning Provides Cardioprotection in a Rat Model of Myocardial Ischemia/Reperfusion Injury.
Topics: Animals; Apoptosis; Cardiotonic Agents; Cytokines; Disease Models, Animal; Inflammation Mediators; Ischemic Preconditioning; Male; Myocardial Reperfusion Injury; Myocytes, Cardiac; Oxidative Stress; Quinuclidines; Rats; Rats, Wistar | 2015 |
Neuroprotective effects of penehyclidine hydrochloride against cerebral ischemia/reperfusion injury in mice.
Topics: Analysis of Variance; Animals; Blood-Brain Barrier; Brain Edema; Brain Infarction; Capillary Permeability; Cytokines; Disease Models, Animal; Dose-Response Relationship, Drug; Glutathione Peroxidase; In Situ Nick-End Labeling; Male; Malondialdehyde; Mice; Mice, Inbred C57BL; Neurologic Examination; Neuroprotective Agents; Quinuclidines; Reperfusion Injury; Superoxide Dismutase; Time Factors | 2016 |
[The effect of penehyclidine hydrochloride on the expression of inflammatory factor in rat with sepsis-associated lung injury].
Topics: Animals; Disease Models, Animal; HMGB1 Protein; Lung; Lung Injury; Male; Quinuclidines; Random Allocation; Rats; Rats, Sprague-Dawley; Sepsis | 2009 |
[Effect of penehyclidine hydrochloride on tumor necrosis factor-alpha in liver and spleen in mice with acute organophosphorus pesticide poisoning].
Topics: Acute Disease; Animals; Disease Models, Animal; Liver; Male; Mice; Mice, Inbred BALB C; Organophosphate Poisoning; Poisoning; Quinuclidines; RNA, Messenger; Spleen; Tumor Necrosis Factor-alpha | 2010 |
[Preventive effects of ischemic postconditioning and penehyclidine hydrochloride on gastric against ischemia-reperfusion injury in rats].
Topics: Animals; Disease Models, Animal; Gastric Mucosa; Ischemia; Ischemic Postconditioning; Male; Quinuclidines; Rats; Rats, Wistar; Reperfusion Injury; Stomach Diseases | 2011 |
[Protective effect of penehyclidine hydrochloride on lung injury in mice with sepsis and its mechanism].
Topics: Animals; Disease Models, Animal; Female; Lung; Lung Injury; Malondialdehyde; Mice; Nitric Oxide Synthase; Quinuclidines; Random Allocation; Sepsis; Superoxide Dismutase | 2007 |