Page last updated: 2024-08-26

lysophosphatidic acid and Pulmonary Fibrosis

lysophosphatidic acid has been researched along with Pulmonary Fibrosis in 15 studies

Research

Studies (15)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (13.33)29.6817
2010's10 (66.67)24.3611
2020's3 (20.00)2.80

Authors

AuthorsStudies
Aidinis, V; Antoniou, K; Karampitsakos, T; Matralis, AN; Ntatsoulis, K; Stylianaki, EA; Tsitoura, E; Tzouvelekis, A1
Chambers, DC; Fieuw, AM; Ford, P; Hopkins, PM; O'Sullivan, B; Powell, JE; Sinclair, KA; Yerkovich, ST1
Dong, S; Li, Y; Mialki, RK; Taleb, SJ; Wei, J; Zhao, J; Zhao, Y1
Cong, CC; Guan, L; Li, SQ; Mao, LJ; Zhang, YL; Zhao, JY1
Budd, DC; Qian, Y1
An, MS; Ding, Q; Feng, R; Li, L; Liu, Y; Tang, N; Wang, S; Wei, W; Wen, J; Zhao, Y1
Cheng, J; Wang, Y; Xie, Y; Zong, C1
Li, J; Sun, X; Wang, G1
Ahluwalia, N; Bain, G; Berdyshev, E; Black, KE; Bronova, I; Castelino, FV; Fontaine, BA; Goulet, L; Knipe, RS; Lagares, D; Natarajan, V; Probst, CK; Shea, BS; Tager, AM1
Aoki, Y; Badri, L; Cao, P; Fearon, ER; Lagstein, A; Lama, VN; Manning, CM; Walker, NM1
Chun, J; Funke, M; Tager, AM; Xu, Y; Zhao, Z1
Alessi, D; Gan, X; Kozasa, T; Offermanns, S; Simon, MI; Sommer, E; Srinivasula, S; Wang, C; Wang, J; Wu, D1
Shea, BS; Tager, AM1
Blackwell, TS; Campanella, GS; Chun, J; Hart, WK; Karimi-Shah, BA; Kim, ND; LaCamera, P; Luster, AD; Pardo, A; Polosukhin, V; Selman, M; Shea, BS; Tager, AM; Wain, J; Xu, Y; Zhao, Z1
Ley, K; Zarbock, A1

Reviews

3 review(s) available for lysophosphatidic acid and Pulmonary Fibrosis

ArticleYear
Commonalities Between ARDS, Pulmonary Fibrosis and COVID-19: The Potential of Autotaxin as a Therapeutic Target.
    Frontiers in immunology, 2021, Volume: 12

    Topics: Anti-Inflammatory Agents; COVID-19; Dexamethasone; Humans; Lung; Lysophospholipids; Phosphoric Diester Hydrolases; Pulmonary Fibrosis; Respiratory Distress Syndrome; SARS-CoV-2; Signal Transduction

2021
Development of lysophosphatidic acid pathway modulators as therapies for fibrosis.
    Future medicinal chemistry, 2013, Volume: 5, Issue:16

    Topics: Animals; Drug Evaluation, Preclinical; Enzyme Inhibitors; Lysophospholipids; Phosphoric Diester Hydrolases; Phosphorous Acids; Pulmonary Fibrosis; Receptors, Lysophosphatidic Acid; Small Molecule Libraries

2013
Role of the lysophospholipid mediators lysophosphatidic acid and sphingosine 1-phosphate in lung fibrosis.
    Proceedings of the American Thoracic Society, 2012, Volume: 9, Issue:3

    Topics: Capillary Permeability; Cell Physiological Phenomena; Epithelial Cells; Fibroblasts; Humans; Lysophospholipids; Pulmonary Alveoli; Pulmonary Fibrosis; Receptors, Lysophosphatidic Acid; Receptors, Lysosphingolipid; Signal Transduction; Sphingosine; Wound Healing

2012

Other Studies

12 other study(ies) available for lysophosphatidic acid and Pulmonary Fibrosis

ArticleYear
The autotaxin-lysophosphatidic acid pathway mediates mesenchymal cell recruitment and fibrotic contraction in lung transplant fibrosis.
    The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation, 2021, Volume: 40, Issue:1

    Topics: Adult; Aged; Biomarkers; Bronchoalveolar Lavage Fluid; Cell Movement; Collagen; Female; Follow-Up Studies; Humans; Lung; Lung Transplantation; Lysophospholipids; Male; Mesenchymal Stem Cells; Middle Aged; Pulmonary Fibrosis; Transplant Recipients

2021
A blocking peptide stabilizes lysophosphatidic acid receptor 1 and promotes lysophosphatidic acid-induced cellular responses.
    Journal of cellular biochemistry, 2021, Volume: 122, Issue:8

    Topics: Animals; Cell Line; Humans; Lysophospholipids; MAP Kinase Signaling System; Mice; Nedd4 Ubiquitin Protein Ligases; Proteasome Endopeptidase Complex; Proteolysis; Pulmonary Fibrosis; Receptors, Lysophosphatidic Acid; Ubiquitin

2021
[The clinical study on the correlation of lysophosphatidic acid and vascular endotheli growth factor and endothelin in serum of pneumoconiosis].
    Zhonghua lao dong wei sheng zhi ye bing za zhi = Zhonghua laodong weisheng zhiyebing zazhi = Chinese journal of industrial hygiene and occupational diseases, 2017, Jul-20, Volume: 35, Issue:7

    Topics: Anthracosis; Coal Mining; Dust; Endothelins; Enzyme-Linked Immunosorbent Assay; Humans; Lysophospholipids; Occupational Diseases; Occupational Exposure; Pneumoconiosis; Pulmonary Fibrosis; Vascular Endothelial Growth Factor A

2017
Lysophosphatidic acid accelerates lung fibrosis by inducing differentiation of mesenchymal stem cells into myofibroblasts.
    Journal of cellular and molecular medicine, 2014, Volume: 18, Issue:1

    Topics: Animals; Bleomycin; Cell Differentiation; Cells, Cultured; Humans; Isoxazoles; Lysophospholipids; Mesenchymal Stem Cells; Mice; Mice, Inbred ICR; Mice, SCID; Mice, Transgenic; Myofibroblasts; Propionates; Pulmonary Fibrosis; Receptors, Lysophosphatidic Acid; Signal Transduction

2014
Transforming growth factor-Beta inhibits heme oxygenase-1 expression in lung fibroblast through nuclear factor-kappa-B-dependent pathway.
    Pharmacology, 2014, Volume: 93, Issue:3-4

    Topics: Animals; Blotting, Western; Cell Differentiation; Fibroblasts; Gene Expression Regulation; Gene Knockdown Techniques; Heme Oxygenase-1; Humans; Lung; Lysophospholipids; Male; Mice; Mice, Inbred C57BL; NF-kappa B; Pulmonary Fibrosis; Transcription Factor RelA; Transforming Growth Factor beta

2014
Transforming growth factor β regulates β-catenin expression in lung fibroblast through NF-κB dependent pathway.
    International journal of molecular medicine, 2014, Volume: 34, Issue:5

    Topics: Animals; beta Catenin; Bleomycin; Cell Differentiation; Cell Line; Fibroblasts; Humans; Lung; Lysophospholipids; Male; Mice; Mice, Inbred C57BL; NF-kappa B; Pulmonary Fibrosis; Transforming Growth Factor beta; Up-Regulation

2014
Autotaxin activity increases locally following lung injury, but is not required for pulmonary lysophosphatidic acid production or fibrosis.
    FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2016, Volume: 30, Issue:6

    Topics: Animals; Antibiotics, Antineoplastic; Benzoates; Bleomycin; Gene Expression Regulation; Lung; Lung Injury; Lysophospholipids; Mice; Mice, Inbred C57BL; Phosphoric Diester Hydrolases; Pulmonary Fibrosis

2016
Autocrine lysophosphatidic acid signaling activates β-catenin and promotes lung allograft fibrosis.
    The Journal of clinical investigation, 2017, Apr-03, Volume: 127, Issue:4

    Topics: Allografts; Animals; Autocrine Communication; beta Catenin; Bronchiolitis Obliterans; Cells, Cultured; Collagen; Female; Graft Rejection; Humans; Lung; Lung Transplantation; Lysophospholipids; Male; Mice, Inbred C57BL; Mice, Inbred DBA; NFATC Transcription Factors; Phosphoric Diester Hydrolases; Pulmonary Fibrosis; Receptors, Lysophosphatidic Acid; Transcriptional Activation

2017
The lysophosphatidic acid receptor LPA1 promotes epithelial cell apoptosis after lung injury.
    American journal of respiratory cell and molecular biology, 2012, Volume: 46, Issue:3

    Topics: Animals; Anoikis; Apoptosis; Bleomycin; Caspase 3; Cell Adhesion; Cells, Cultured; Disease Models, Animal; Epithelial Cells; Fibroblasts; Humans; Lung; Lung Injury; Lysophospholipids; Mice; Mice, 129 Strain; Mice, Inbred C57BL; Mice, Knockout; Pulmonary Fibrosis; Rats; Receptors, Lysophosphatidic Acid; Signal Transduction; Time Factors

2012
PRR5L degradation promotes mTORC2-mediated PKC-δ phosphorylation and cell migration downstream of Gα12.
    Nature cell biology, 2012, May-20, Volume: 14, Issue:7

    Topics: Amino Acid Motifs; Animals; Apoptosis Regulatory Proteins; Bleomycin; Cell Movement; Disease Models, Animal; Enzyme Activation; Enzyme Stability; Extracellular Signal-Regulated MAP Kinases; Fibroblasts; GTP-Binding Protein alpha Subunits, G12-G13; HEK293 Cells; Humans; Intracellular Signaling Peptides and Proteins; Lung; Lysophospholipids; Mechanistic Target of Rapamycin Complex 2; Mice; Mice, Inbred C57BL; Mice, Knockout; Multiprotein Complexes; Phosphorylation; Protein Kinase C-delta; Protein Stability; Proteins; Proto-Oncogene Proteins c-akt; Pulmonary Fibrosis; RNA Interference; Signal Transduction; Time Factors; TOR Serine-Threonine Kinases; Trans-Activators; Transfection; Ubiquitin-Protein Ligases; Ubiquitination

2012
The lysophosphatidic acid receptor LPA1 links pulmonary fibrosis to lung injury by mediating fibroblast recruitment and vascular leak.
    Nature medicine, 2008, Volume: 14, Issue:1

    Topics: Animals; Bleomycin; Bronchoalveolar Lavage Fluid; Female; Fibroblasts; Leukocytes; Lung; Lung Injury; Lysophospholipids; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Models, Biological; Pulmonary Fibrosis; Receptors, Lysophosphatidic Acid

2008
From lung injury to fibrosis.
    Nature medicine, 2008, Volume: 14, Issue:1

    Topics: Animals; Fibroblasts; Fibrosis; Humans; Lung; Lung Diseases; Lung Injury; Lysophospholipids; Macrophages; Models, Biological; Pulmonary Alveoli; Pulmonary Fibrosis; Receptors, Lysophosphatidic Acid

2008