Page last updated: 2024-08-26

lysophosphatidic acid and Pancreatic Neoplasms

lysophosphatidic acid has been researched along with Pancreatic Neoplasms in 19 studies

Research

Studies (19)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's3 (15.79)29.6817
2010's13 (68.42)24.3611
2020's3 (15.79)2.80

Authors

AuthorsStudies
Liao, Y; Liu, L; Shi, Z; Yang, J1
Ikeda, H; Kurisu, R; Okuda, A; Takai, M; Takamoto, M; Tsujiuchi, T1
Cutiongco, MFA; Fort, L; Gadegaard, N; Insall, RH; Juin, A; Kalna, G; Koh, YWH; Lilla, S; Machesky, LM; Mackay, G; Martin, KJ; McGhee, E; Neilson, M; Norman, JC; Spence, HJ; Thomason, P1
Chen, J; Guo, X; Li, H; Xu, W1
Cui, JJ; Feng, X; Huang, Q; Quan, M1
Itadani, M; Katase, N; Kobiki, K; Kuribayashi, F; Nakamura, M; Okada, N; Yamaguchi, Y; Yamamura, M; Yamauchi, A1
Dhanasekaran, DN; Gardner, JA; Ha, JH; Jayaraman, M1
Liao, Y; Mu, G; Yu, H; Zhang, J; Zhang, L; Zhou, W1
Fukushima, K; Fukushima, N; Hirane, M; Ishii, S; Tomimatsu, A; Tsujiuchi, T1
Chen, L; Hu, Y; Xing, J; Zheng, Y; Zhou, Z1
Aasrum, M; Brusevold, IJ; Christoffersen, T; Sandnes, D; Tveteraas, IH; Ødegård, J1
Fukushima, K; Fukushima, N; Honoki, K; Onishi, Y; Takahashi, K; Tsujiuchi, T; Yamasaki, E1
Arita, Y; Hisano, T; Ito, T; Kawabe, K; Oono, T; Takayanagi, R1
Im, DS; Kimura, T; Komachi, M; Kurose, H; Kuwabara, A; Malchinkhuu, E; Mogi, C; Ohta, H; Okajima, F; Sato, K; Takeyoshi, I; Tobo, M; Tomura, H; Yamada, T1
Chen, JF; Gong, YL; Li, P; Lv, GM; Wang, ShK; Wang, WD1
Im, DS; Ishii, S; Kimura, T; Komachi, M; Mogi, C; Ohta, H; Okajima, F; Sato, K; Takeyoshi, I; Tobo, M; Tomura, H; Yamada, T; Yanagida, K1
Fukui, R; Fukushima, N; Kato, K; Kitayoshi, M; Tanabe, E; Tsujiuchi, T; Yoshikawa, K1
Fukushima, N; Inoue, S; Kitayoshi, M; Okimoto, S; Shibata, A; Tanabe, E; Tsujiuchi, T; Yoshikawa, K1
Beil, M; Dao, M; Lim, CT; Micoulet, A; Mills, JP; Seufferlein, T; Spatz, J; Suresh, S1

Reviews

3 review(s) available for lysophosphatidic acid and Pancreatic Neoplasms

ArticleYear
The critical role and potential target of the autotaxin/lysophosphatidate axis in pancreatic cancer.
    Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine, 2017, Volume: 39, Issue:3

    Topics: Cell Movement; Drug Resistance, Neoplasm; Humans; Lysophospholipids; Neoplasm Invasiveness; Neoplastic Stem Cells; Pancreatic Neoplasms; Phosphoric Diester Hydrolases; Receptors, Lysophosphatidic Acid; Signal Transduction; Tumor Microenvironment

2017
Lysophosphatidic acid (LPA) and endothelial differentiation gene (Edg) receptors in human pancreatic cancer.
    Journal of surgical oncology, 2011, Nov-01, Volume: 104, Issue:6

    Topics: Animals; Humans; Lysophospholipids; Pancreatic Neoplasms; Receptors, Lysosphingolipid

2011
Connections between single-cell biomechanics and human disease states: gastrointestinal cancer and malaria.
    Acta biomaterialia, 2005, Volume: 1, Issue:1

    Topics: Animals; Biomechanical Phenomena; Cell Line, Tumor; Elasticity; Erythrocyte Deformability; Erythrocytes; Gastrointestinal Neoplasms; Humans; In Vitro Techniques; Lysophospholipids; Malaria; Pancreatic Neoplasms; Phosphorylcholine; Plasmodium falciparum; Sphingosine

2005

Other Studies

16 other study(ies) available for lysophosphatidic acid and Pancreatic Neoplasms

ArticleYear
ATX/LPA axis regulates FAK activation, cell proliferation, apoptosis, and motility in human pancreatic cancer cells.
    In vitro cellular & developmental biology. Animal, 2022, Volume: 58, Issue:4

    Topics: Animals; Apoptosis; Cell Proliferation; Focal Adhesion Protein-Tyrosine Kinases; Humans; Lysophospholipids; Pancreatic Neoplasms; Signal Transduction

2022
Roles of lysophosphatidic acid (LPA) receptor-2 (LPA
    International journal of radiation biology, 2023, Volume: 99, Issue:12

    Topics: Cell Movement; Cisplatin; Humans; Hydrogen Peroxide; Pancreatic Neoplasms; Reactive Oxygen Species; X-Rays

2023
N-WASP Control of LPAR1 Trafficking Establishes Response to Self-Generated LPA Gradients to Promote Pancreatic Cancer Cell Metastasis.
    Developmental cell, 2019, 11-18, Volume: 51, Issue:4

    Topics: Animals; Carcinoma, Pancreatic Ductal; Cell Line, Tumor; Cell Movement; Chemotaxis; Female; Humans; Lysophospholipids; Male; Mice; Mice, Nude; Neoplasm Invasiveness; Neoplasm Metastasis; Pancreatic Neoplasms; Protein Transport; Rats; Receptors, Lysophosphatidic Acid; rhoA GTP-Binding Protein; Signal Transduction; Sorting Nexins; Wiskott-Aldrich Syndrome Protein, Neuronal

2019
Evaluation of serum ATX and LPA as potential diagnostic biomarkers in patients with pancreatic cancer.
    BMC gastroenterology, 2021, Feb-10, Volume: 21, Issue:1

    Topics: Biomarkers; Humans; Lipoprotein(a); Lysophospholipids; Pancreatic Neoplasms; Phosphoric Diester Hydrolases; Prognosis

2021
Evaluation of pancreatic cancer cell migration with multiple parameters in vitro by using an optical real-time cell mobility assay device.
    BMC cancer, 2017, 03-31, Volume: 17, Issue:1

    Topics: Cell Movement; Humans; In Vitro Techniques; Lysophospholipids; Optical Devices; Pancreatic Neoplasms; Receptors, Lysophosphatidic Acid; Signal Transduction; Tumor Cells, Cultured

2017
The gep proto-oncogene Gα13 mediates lysophosphatidic acid-mediated migration of pancreatic cancer cells.
    Pancreas, 2013, Volume: 42, Issue:5

    Topics: Cell Line, Tumor; Cell Movement; Gene Expression Regulation, Neoplastic; GTP-Binding Protein alpha Subunits, G12-G13; Humans; Immunoblotting; Lysophospholipids; Pancreatic Neoplasms; Protein Binding; Proto-Oncogene Mas; Receptors, Lysophosphatidic Acid; Reverse Transcriptase Polymerase Chain Reaction; RNA Interference

2013
Lysophosphatidic acid stimulates activation of focal adhesion kinase and paxillin and promotes cell motility, via LPA1-3, in human pancreatic cancer.
    Digestive diseases and sciences, 2013, Volume: 58, Issue:12

    Topics: Carcinoma; Cell Line, Tumor; Cell Movement; Enzyme Activation; Focal Adhesion Protein-Tyrosine Kinases; Humans; Lysophospholipids; Pancreatic Neoplasms; Paxillin; Receptors, Lysophosphatidic Acid; RNA, Messenger

2013
Diverse effects of LPA4, LPA5 and LPA6 on the activation of tumor progression in pancreatic cancer cells.
    Biochemical and biophysical research communications, 2015, May-22, Volume: 461, Issue:1

    Topics: Cell Line, Tumor; Cell Movement; Humans; Lysophospholipids; Neoplasm Invasiveness; Pancreatic Neoplasms; Receptors, Lysophosphatidic Acid; Receptors, Purinergic; Receptors, Purinergic P2

2015
RGS22 inhibits pancreatic adenocarcinoma cell migration through the G12/13 α subunit/F-actin pathway.
    Oncology reports, 2015, Volume: 34, Issue:5

    Topics: Actins; Antigens, Surface; Carcinoma, Pancreatic Ductal; Cell Line, Tumor; Cell Movement; Cell Shape; GTP-Binding Protein alpha Subunits, G12-G13; GTP-Binding Protein Regulators; Humans; Lysophospholipids; Pancreatic Neoplasms; Tumor Suppressor Proteins

2015
Lysophosphatidic acid induces both EGFR-dependent and EGFR-independent effects on DNA synthesis and migration in pancreatic and colorectal carcinoma cells.
    Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine, 2016, Volume: 37, Issue:2

    Topics: Carcinoma; Cell Line, Tumor; Cell Movement; Cell Proliferation; Colorectal Neoplasms; DNA; ErbB Receptors; Gefitinib; HCT116 Cells; HT29 Cells; Humans; Lysophospholipids; Pancreatic Neoplasms; Phosphorylation; Proto-Oncogene Proteins c-akt; Quinazolines; Signal Transduction; Transcriptional Activation

2016
Lysophosphatidic acid signaling via LPA
    Experimental cell research, 2017, 03-01, Volume: 352, Issue:1

    Topics: Antineoplastic Agents; Apoptosis; Blotting, Western; Cell Movement; Cell Proliferation; Cisplatin; Disease Progression; Drug Therapy, Combination; Humans; Lysophospholipids; Matrix Metalloproteinase 2; Pancreatic Neoplasms; Real-Time Polymerase Chain Reaction; Receptors, Lysophosphatidic Acid; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; RNA, Small Interfering; Tumor Cells, Cultured

2017
Lysophosphatidic acid induced nuclear translocation of nuclear factor-kappaB in Panc-1 cells by mobilizing cytosolic free calcium.
    World journal of gastroenterology, 2008, Jul-28, Volume: 14, Issue:28

    Topics: Adenocarcinoma; Calcium; Cell Line, Tumor; Cell Nucleus; Cytoplasm; Dose-Response Relationship, Drug; Humans; Lysophospholipids; NF-kappa B; Pancreatic Neoplasms; Protein Kinase C; Receptors, Lysophosphatidic Acid; RNA, Messenger; Type C Phospholipases

2008
LPA1 receptors mediate stimulation, whereas LPA2 receptors mediate inhibition, of migration of pancreatic cancer cells in response to lysophosphatidic acid and malignant ascites.
    Carcinogenesis, 2009, Volume: 30, Issue:3

    Topics: Ascites; Cell Line, Tumor; Cell Movement; Collagen; Drug Combinations; Epidermal Growth Factor; GTP-Binding Protein alpha Subunits, Gi-Go; Humans; Isoxazoles; Laminin; Lysophospholipids; Neoplasm Invasiveness; Pancreatic Neoplasms; Pertussis Toxin; Propionates; Proteoglycans; Receptors, Lysophosphatidic Acid; rhoA GTP-Binding Protein; RNA, Small Interfering

2009
Orally active lysophosphatidic acid receptor antagonist attenuates pancreatic cancer invasion and metastasis in vivo.
    Cancer science, 2012, Volume: 103, Issue:6

    Topics: Animals; Ascites; Cell Line, Tumor; Cell Movement; Humans; Isoxazoles; Lysophospholipids; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Matrix Metalloproteinase Inhibitors; Mice; Mice, Inbred BALB C; Mice, Nude; Neoplasm Invasiveness; Neoplasm Metastasis; Pancreatic Neoplasms; Peritoneal Neoplasms; Propionates; Receptors, Lysophosphatidic Acid; Xenograft Model Antitumor Assays

2012
Opposite roles of LPA1 and LPA3 on cell motile and invasive activities of pancreatic cancer cells.
    Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine, 2012, Volume: 33, Issue:5

    Topics: Animals; Cell Line, Tumor; Cell Movement; Cricetinae; Gene Knockdown Techniques; Lysophospholipids; Neoplasm Invasiveness; Pancreatic Neoplasms; Receptors, Lysophosphatidic Acid

2012
Involvement of oncogenic K-ras on cell migration stimulated by lysophosphatidic acid receptor-2 in pancreatic cancer cells.
    Experimental cell research, 2013, Feb-01, Volume: 319, Issue:3

    Topics: Adenocarcinoma; Animals; Carcinoma, Pancreatic Ductal; Cell Line, Tumor; Cell Movement; Cricetinae; Diphosphates; Gene Knockdown Techniques; Genes, ras; Glycerol; Lysophospholipids; Neoplasm Invasiveness; Pancreatic Neoplasms; Receptors, Lysophosphatidic Acid; Up-Regulation

2013