lysophosphatidic acid has been researched along with Neuralgia in 29 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (3.45) | 29.6817 |
| 2010's | 20 (68.97) | 24.3611 |
| 2020's | 8 (27.59) | 2.80 |
| Authors | Studies |
|---|---|
| Chun, J; Cincilla, G; Del Valle, CR; Devesa, I; Ferrer-Montiel, AV; González-Gil, I; Hernández-Torres, G; Khiar-Fernández, N; Kihara, Y; López-Rodríguez, ML; López-Vales, R; Martínez, RF; Mathivanan, S; Ortega-Gutiérrez, S; Puigdomenech, M; Rivera, R; Rodríguez de Fonseca, F; Sanchez-Martinez, M; Vázquez-Villa, H; Zambrana-Infantes, E; Zian, D | 1 |
| Agalave, N; Barde, S; Chun, J; Delaney, A; Hökfelt, T; Josephson, A; Kato, J; Krock, E; Kultima, K; Matteo, R; Peyruchaud, O; Ribeiro, J; Sabbadini, R; Su, J; Svensson, CI; Wigerblad, G | 1 |
| McDougall, JJ; Reid, AR | 1 |
| Ueda, H | 5 |
| Aoki, J; Ikeda, H; Ito, N; Kano, K; Kurano, M; Saigusa, D; Saito, R; Sekiguchi, M; Sumitani, M; Uranbileg, B; Uruno, A; Yamada, Y; Yatomi, Y | 1 |
| Birgbauer, E | 1 |
| Aoki, J; Ito, N; Kano, K; Kurano, M; Sumitani, M; Uchida, K; Uranbileg, B; Yatomi, Y | 1 |
| Düll, MM; Kremer, AE; Namer, B; Reeh, PW; Ries, V; Stengel, M; Strupf, M | 1 |
| Aoki, T; Hiyama, H; Kiso, T; Murai, N; Oka, H; Sekizawa, T; Watabiki, T | 1 |
| Akahoshi, N; Araki, K; Araki, M; Gotoh, M; Ishii, S; Murakami-Murofushi, K; Neyama, H; Sumida, H; Tsukahara, R; Tsukahara, T; Ueda, H; Yamamoto, S; Yamamura, KI; Yanagida, K; Yoshikawa, K | 1 |
| Matsushita, Y; Nagai, J; Neyama, H; Tsukahara, R; Tsukahara, T; Ueda, H | 1 |
| Aoki, J; Kano, K; Kurano, M; Kuwajima, K; Nishikawa, M; Ogata, T; Sumitani, M; Tsuchida, R; Uranbileg, B; Yamada, Y; Yatomi, Y | 1 |
| Arima, H; Banno, T; Eto, F; Hanada, M; Horikawa, M; Matsuyama, Y; Mihara, Y; Okamoto, A; Omura, T; Sato, S; Setou, M; Takei, S; Ushirozako, H; Xu, D; Yamada, T; Yamazaki, F; Yao, I | 1 |
| Chun, J; Ma, L; Nagai, J; Ueda, H | 1 |
| Ma, L; Nagai, J; Ueda, H; Yano, R | 1 |
| Beuers, UH; Bolier, R; Oude Elferink, RP | 1 |
| Nagai, J; Uchida, H; Ueda, H | 1 |
| O'Sullivan, C; Sheridan, GK; Velasco, M | 1 |
| Albacete, S; Bui, HH; Chambers, MG; Lin, C; McDougall, JJ; Mitchell, PG; Oskins, JL; Schuelert, N | 1 |
| Aoki, J; Chun, J; Inoue, M; Ma, L; Nagai, J; Uchida, H; Ueda, H | 1 |
| Aoki, J; Inoue, M; Ma, L; Nagai, J; Uchida, H; Ueda, H | 1 |
| Kato, A; Ogawa, K; Shinohara, S; Takasu, K; Yoneda, Y | 1 |
| Chun, J; Lin, ME; Rivera, RR | 1 |
| Matsunaga, H; Nagai, J; Olaposi, OI; Ueda, H | 1 |
| Kashimoto, R; Kobayashi, K; Mimura, O; Noguchi, K; Okubo, M; Yagi, H; Yamanaka, H | 1 |
8 review(s) available for lysophosphatidic acid and Neuralgia
| Article | Year |
|---|---|
Systems Pathology of Neuropathic Pain and Fibromyalgia.
Topics: Animals; Chronic Pain; Fibromyalgia; Inflammation; Lysophospholipids; Mice; Neuralgia; Receptors, Lysophosphatidic Acid; Signal Transduction | 2019 |
LPA receptor signaling as a therapeutic target for radical treatment of neuropathic pain and fibromyalgia.
Topics: Animals; Chronic Pain; Fibromyalgia; Humans; Lysophospholipids; Neuralgia; Receptors, Lysophosphatidic Acid; Signal Transduction | 2020 |
Lysophosphatidic Acid Signalling in Nervous System Development and Function.
Topics: Animals; Axons; Brain; Brain Injuries; Central Nervous System; Cerebrovascular Disorders; Diabetic Retinopathy; Glaucoma; Humans; Lysophospholipids; Mice; Mice, Knockout; Nerve Tissue Proteins; Neural Stem Cells; Neuralgia; Neurodevelopmental Disorders; Neuroglia; Rats; Receptors, G-Protein-Coupled; Receptors, Lysophosphatidic Acid; Signal Transduction; Spinal Cord Injuries | 2021 |
Pathogenic mechanisms of lipid mediator lysophosphatidic acid in chronic pain.
Topics: Animals; Chronic Pain; Lysophospholipids; Neuralgia; Receptors, Lysophosphatidic Acid | 2021 |
Lysophosphatidic acid and signaling in sensory neurons.
Topics: Animals; Humans; Lysophospholipids; Neuralgia; Receptors, G-Protein-Coupled; Sensory Receptor Cells; Signal Transduction | 2015 |
Lysophosphatidic acid receptors (LPARs): Potential targets for the treatment of neuropathic pain.
Topics: Analgesics; Animals; Humans; Lysophospholipids; Neuralgia; Receptors, Lysophosphatidic Acid | 2017 |
Lysophosphatidic acid signaling is the definitive mechanism underlying neuropathic pain.
Topics: Animals; Humans; Lysophospholipids; Neuralgia; Signal Transduction | 2017 |
Lysophosphatidic acid: chemical signature of neuropathic pain.
Topics: Animals; Demyelinating Diseases; Humans; Lysophospholipids; Models, Biological; Neuralgia; Neurons; Signal Transduction | 2013 |
1 trial(s) available for lysophosphatidic acid and Neuralgia
| Article | Year |
|---|---|
Lysophosphatidic acid is associated with neuropathic pain intensity in humans: An exploratory study.
Topics: Adult; Aged; Aged, 80 and over; Female; Humans; Lysophospholipids; Male; Middle Aged; Neuralgia; Pain Management; Phosphoric Diester Hydrolases | 2018 |
20 other study(ies) available for lysophosphatidic acid and Neuralgia
| Article | Year |
|---|---|
A Novel Agonist of the Type 1 Lysophosphatidic Acid Receptor (LPA
Topics: Analgesics; Animals; Cell Line; Cell Movement; Cells, Cultured; Drug Discovery; Female; Humans; Hydrocarbons, Aromatic; Mice, Inbred C57BL; Models, Molecular; Neuralgia; Pain Perception; Rats, Wistar; Receptors, Lysophosphatidic Acid; Sensory Receptor Cells | 2020 |
Pain-like behavior in the collagen antibody-induced arthritis model is regulated by lysophosphatidic acid and activation of satellite glia cells.
Topics: Animals; Antibodies; Arthritis, Experimental; Collagen; Ganglia, Spinal; Humans; Lysophospholipids; Mice; Neuralgia; Neuroglia; Sensory Receptor Cells | 2022 |
Joint Damage and Neuropathic Pain in Rats Treated With Lysophosphatidic Acid.
Topics: Animals; Arthralgia; Arthritis, Experimental; Disease Models, Animal; Female; Hyperalgesia; Injections, Intra-Articular; Knee Joint; Lysophospholipids; Male; Neuralgia; Pain Threshold; Rats; Rats, Wistar | 2022 |
Alteration of the lysophosphatidic acid and its precursor lysophosphatidylcholine levels in spinal cord stenosis: A study using a rat cauda equina compression model.
Topics: Animals; Cauda Equina; Constriction, Pathologic; Disease Models, Animal; Female; Gene Expression Regulation; Lysophosphatidylcholines; Lysophospholipids; Neuralgia; Rats, Sprague-Dawley; Receptors, Lysophosphatidic Acid; RNA, Messenger; Spinal Cord | 2019 |
Inhibition of autotaxin activity ameliorates neuropathic pain derived from lumbar spinal canal stenosis.
Topics: Animals; Behavior, Animal; Carbolines; Cerebrospinal Fluid; Disease Models, Animal; Female; Ganglia, Spinal; Humans; Lysophosphatidylcholines; Lysophospholipids; Mice; Neuralgia; Phosphodiesterase Inhibitors; Phosphoric Diester Hydrolases; Rats, Sprague-Dawley; Spinal Canal; Spinal Stenosis | 2021 |
Lysophosphatidic acid activates nociceptors and causes pain or itch depending on the application mode in human skin.
Topics: Animals; Histamine; Humans; Lysophospholipids; Nerve Fibers, Unmyelinated; Neuralgia; Nociceptors; Pruritus; Skin | 2022 |
Analgesic effects of novel lysophosphatidic acid receptor 5 antagonist AS2717638 in rodents.
Topics: Analgesics; Animals; Benzoxazoles; Cells, Cultured; Cyclic AMP; Female; Hyperalgesia; Inflammation; Injections, Spinal; Isoquinolines; Lysophospholipids; Male; Mice, Inbred C57BL; Mice, Knockout; Neuralgia; Pain; Pain Threshold; Piperidines; Polyisoprenyl Phosphates; Rats, Inbred Lew; Rats, Sprague-Dawley; Receptors, Lysophosphatidic Acid | 2017 |
LPA5 signaling is involved in multiple sclerosis-mediated neuropathic pain in the cuprizone mouse model.
Topics: Animals; Corpus Callosum; Cuprizone; Disease Models, Animal; Female; Gene Expression; Lysophospholipids; Male; Mice, Inbred Strains; Multiple Sclerosis; Neuralgia; Receptors, Lysophosphatidic Acid; Signal Transduction | 2018 |
Involvement of lysophosphatidic acid-induced astrocyte activation underlying the maintenance of partial sciatic nerve injury-induced neuropathic pain.
Topics: 2-Aminoadipic Acid; Animals; Animals, Newborn; Astrocytes; Cells, Cultured; Chemokine CXCL1; Disease Models, Animal; Dose-Response Relationship, Drug; Glial Fibrillary Acidic Protein; Lysophospholipids; Male; Mice; Mice, Inbred C57BL; Neuralgia; Pain Measurement; Pain Threshold; Pyridines; RNA, Messenger; Sciatic Neuropathy; Spinal Cord; Up-Regulation | 2018 |
Lysophosphatidic acid precursor levels decrease and an arachidonic acid-containing phosphatidylcholine level increases in the dorsal root ganglion of mice after peripheral nerve injury.
Topics: Animals; Arachidonic Acid; Ganglia, Spinal; Lysophospholipids; Mice, Inbred C57BL; Neuralgia; Phosphatidic Acids; Phosphatidylcholines; Sciatic Nerve | 2019 |
An LPA species (18:1 LPA) plays key roles in the self-amplification of spinal LPA production in the peripheral neuropathic pain model.
Topics: Animals; Lysophospholipids; Male; Mice; Neuralgia; Neurons; Phospholipases A2, Cytosolic; Pyridines; Receptors, Lysophosphatidic Acid; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization | 2013 |
Interleukin-1β plays key roles in LPA-induced amplification of LPA production in neuropathic pain model.
Topics: Animals; Antibodies, Neutralizing; Disease Models, Animal; Gene Expression Regulation; Group IV Phospholipases A2; Interleukin-1beta; Lysophospholipids; Male; Mice; Mice, Inbred C57BL; Neuralgia; Phospholipases A2, Calcium-Independent; Posterior Horn Cells; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization | 2013 |
Lysophosphatidic acid and its receptors LPA1 and LPA3 mediate paclitaxel-induced neuropathic pain in mice.
Topics: Animals; Antineoplastic Agents, Phytogenic; Disease Models, Animal; Dizocilpine Maleate; Lysophospholipids; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Neuralgia; Paclitaxel; Pain Measurement; Phospholipases A2; Piperidines; Receptors, Lysophosphatidic Acid; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Spinal Cord Dorsal Horn; Time Factors | 2014 |
Lysophosphatidic acid provides a missing link between osteoarthritis and joint neuropathic pain.
Topics: Activating Transcription Factor 3; Adult; Aged; Aged, 80 and over; Animals; Arthralgia; Arthritis, Experimental; Behavior, Animal; Case-Control Studies; Chromatography, Liquid; Enzyme Inhibitors; Female; Humans; Injections, Intra-Articular; Iodoacetic Acid; Isoxazoles; Lysophospholipids; Male; Middle Aged; Neural Conduction; Neuralgia; Osteoarthritis; Osteoarthritis, Knee; Peripheral Nerves; Propionates; Rats, Inbred Lew; Synovial Fluid | 2017 |
Lysophosphatidic acid-3 receptor-mediated feed-forward production of lysophosphatidic acid: an initiator of nerve injury-induced neuropathic pain.
Topics: Animals; Cell Line, Tumor; Ganglia, Spinal; Hyperalgesia; In Vitro Techniques; Lysophosphatidylcholines; Lysophospholipids; Male; Mice; Mice, Inbred C57BL; Mice, Mutant Strains; Multienzyme Complexes; Neuralgia; Phosphodiesterase I; Phosphoric Diester Hydrolases; Posterior Horn Cells; Pyrophosphatases; Rats; Receptors, Lysophosphatidic Acid; Reverse Transcriptase Polymerase Chain Reaction; Spinal Cord; Spinal Nerve Roots | 2009 |
Evidence for de novo synthesis of lysophosphatidic acid in the spinal cord through phospholipase A2 and autotaxin in nerve injury-induced neuropathic pain.
Topics: Animals; Arachidonic Acids; Blotting, Western; Cell Line; Injections, Spinal; Lysophosphatidylcholines; Lysophospholipids; Male; Mice; Mice, Inbred C57BL; Multienzyme Complexes; Naphthalenes; Neuralgia; Pain Measurement; Phosphodiesterase I; Phospholipase A2 Inhibitors; Phospholipases A2; Phosphoric Diester Hydrolases; Posterior Horn Cells; Pyrones; Pyrophosphatases; Sciatic Nerve; Spinal Nerve Roots | 2010 |
Lysophosphatidic acid as the initiator of neuropathic pain.
Topics: Animals; Calcium; Demyelinating Diseases; Hyperalgesia; Lysophospholipids; Microglia; Myelin Sheath; Neuralgia; Peripheral Nervous System; Peripheral Nervous System Diseases; Protein Kinase C; Receptors, Lysophosphatidic Acid; Sensory Receptor Cells; Signal Transduction; Spinal Cord; Synapses; Up-Regulation | 2011 |
Pharmacological characterization of lysophosphatidic acid-induced pain with clinically relevant neuropathic pain drugs.
Topics: Amines; Analgesics; Animals; Calcium Channels; Cyclohexanecarboxylic Acids; Disease Models, Animal; Gabapentin; gamma-Aminobutyric Acid; Ganglia, Spinal; Hyperalgesia; Indomethacin; Lysophospholipids; Male; Mice; Morphine; Motor Activity; Neuralgia; Neurons; Pregabalin; Spinal Cord | 2012 |
Targeted deletion of LPA5 identifies novel roles for lysophosphatidic acid signaling in development of neuropathic pain.
Topics: Animals; Cyclic AMP; Ganglia, Spinal; Gene Deletion; GTP-Binding Protein alpha Subunits, G12-G13; Lysophospholipids; Mice; Mice, Knockout; Nerve Tissue Proteins; Neuralgia; Receptors, Lysophosphatidic Acid; Response Elements; Signal Transduction; Transcription Factors | 2012 |
Phosphorylation of ezrin/radixin/moesin (ERM) protein in spinal microglia following peripheral nerve injury and lysophosphatidic acid administration.
Topics: Animals; Behavior, Animal; Cytoskeletal Proteins; Hyperalgesia; Lysophospholipids; Male; Membrane Proteins; Microfilament Proteins; Microglia; Neuralgia; Peripheral Nerve Injuries; Phosphorylation; Physical Stimulation; Rats; Rats, Sprague-Dawley; Spinal Cord | 2013 |