Page last updated: 2024-08-26

lysophosphatidic acid and Malignant Melanoma

lysophosphatidic acid has been researched along with Malignant Melanoma in 16 studies

Research

Studies (16)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's4 (25.00)29.6817
2010's11 (68.75)24.3611
2020's1 (6.25)2.80

Authors

AuthorsStudies
Ishimoto, K; Minami, K; Tsujiuchi, T; Ueda, N1
Insall, RH; Kamphorst, JJ; Koh, YWH; Mackay, GM; Morrice, N; Muinonen-Martin, AJ; Nielson, M; Susanto, O; Thomason, PA; Tumanov, S; Tweedy, L1
Hegedüs, B; Rásó, E; Tímár, J1
Ishimoto, K; Maeda, H; Minami, K; Otagaki, S; Tsujiuchi, T; Ueda, N1
Al-Shami, A; Fujiwara, Y; Oda, SK; Oravecz, T; Pelanda, R; Strauch, P; Tigyi, G; Torres, RM1
Bennett, DC; Faller, WJ; Herd, R; Insall, RH; Jones, R; Kalna, G; Knecht, DA; Lindsay, C; Machesky, LM; Muinonen-Martin, AJ; Sansom, OJ; Smethurst, E; Susanto, O; Veltman, DM; Wakelam, MJ; Zhang, Q1
Argenzio, E; Boumeester, AJ; Innocenti, M; Jalink, K; Kedziora, KM; Leyton-Puig, D; Moolenaar, WH; van Butselaar, B; van Leeuwen, FN; Wu, YI; Yin, T1
Hövelmann, F; Jalink, K; Kedziora, KM; Müller, R; Nadler, A; Schultz, C1
Chen, XP; Kang, TS; Ko, CN; Leung, CH; Liang, JX; Lu, JJ; Ma, DL; Wang, W; Zhong, HJ1
Brindley, DN; Gaetano, C; Goping, IS; Samadi, N1
Brindley, DN; Gaetano, CG; Lynch, KR; Macdonald, TL; Samadi, N; Tomsig, JL1
Barz, D; Berod, L; Idzko, M; Kamradt, T; Lagadari, M; Lehmann, K; Maghazachi, AA; Norgauer, J; Truta-Feles, K; Ziemer, M1
Berliner, C; Bialecki, W; Kleuser, B; Leptin, J; Milićević, NM; Müller, R; Pörtner, D; Schumacher, U1
Bar-Eli, M; Calderone, TL; Davies, MA; Gershenwald, JE; Mills, GB; Mu, H; Prieto, VG; Wang, H1
Baker, DL; Bandle, RW; Bittman, R; Byun, HS; Fan, D; Fujiwara, Y; Kobayashi, S; Koh, E; Mills, GB; Murakami-Murofushi, K; Murofushi, H; Murph, M; Pigg, KR; Tigyi, G; Tsukahara, R; Uchiyama, A1
Baker, DL; Banerjee, S; Lee, SC; Miller, DD; Norman, DD; Parrill, AL; Pham, TC; Tigyi, GJ1

Reviews

1 review(s) available for lysophosphatidic acid and Malignant Melanoma

ArticleYear
The role of lipid signaling in the progression of malignant melanoma.
    Cancer metastasis reviews, 2018, Volume: 37, Issue:2-3

    Topics: Animals; Arachidonic Acid; Cyclooxygenase 2; Disease Progression; Endocannabinoids; Genetic Predisposition to Disease; Humans; Lipid Metabolism; Lysophospholipids; Melanoma; Metabolic Networks and Pathways; Phosphatidylinositol 3-Kinases; Phospholipases; Phosphoric Diester Hydrolases; Prenylation; Prostaglandins; Receptors, Lysophosphatidic Acid; Signal Transduction

2018

Other Studies

15 other study(ies) available for lysophosphatidic acid and Malignant Melanoma

ArticleYear
Lysophosphatidic acid receptor-2 (LPA
    Molecular and cellular biochemistry, 2020, Volume: 469, Issue:1-2

    Topics: Antineoplastic Agents; Cell Line, Tumor; Cell Survival; Cisplatin; Dacarbazine; Drug Resistance, Neoplasm; Gene Knockdown Techniques; Humans; Lysophospholipids; Melanoma; Pertussis Toxin; Receptors, Lysophosphatidic Acid; Signal Transduction

2020
LPP3 mediates self-generation of chemotactic LPA gradients by melanoma cells.
    Journal of cell science, 2017, Oct-15, Volume: 130, Issue:20

    Topics: Cell Line, Tumor; Chemotaxis; Humans; Lysophospholipids; Melanoma; Neoplasm Invasiveness; Phosphatidate Phosphatase; Skin Neoplasms

2017
Modulation of chemoresistance by lysophosphatidic acid (LPA) signaling through LPA
    Biochemical and biophysical research communications, 2019, 09-17, Volume: 517, Issue:2

    Topics: Antineoplastic Agents; Cell Line, Tumor; Cell Movement; Cell Survival; Cisplatin; Dacarbazine; Drug Resistance, Neoplasm; Gene Expression Regulation, Neoplastic; Gene Knockdown Techniques; Humans; Lysophospholipids; Melanoma; Receptors, Lysophosphatidic Acid; Signal Transduction

2019
Lysophosphatidic acid inhibits CD8 T cell activation and control of tumor progression.
    Cancer immunology research, 2013, Volume: 1, Issue:4

    Topics: Animals; Carcinogenesis; CD8-Positive T-Lymphocytes; Cell Line, Tumor; Immunologic Surveillance; Lymphocyte Activation; Lysophospholipids; Melanoma; Mice; Mice, Inbred C57BL; Mice, Knockout; Neoplastic Processes; Receptors, Lysophosphatidic Acid; Signal Transduction

2013
Melanoma cells break down LPA to establish local gradients that drive chemotactic dispersal.
    PLoS biology, 2014, Volume: 12, Issue:10

    Topics: Animals; Cell Movement; Chemotaxis; Intercellular Signaling Peptides and Proteins; Lysophospholipids; Melanoma; Mice; Neoplasm Metastasis

2014
Rapid Remodeling of Invadosomes by Gi-coupled Receptors: DISSECTING THE ROLE OF Rho GTPases.
    The Journal of biological chemistry, 2016, Feb-26, Volume: 291, Issue:9

    Topics: Biomarkers; cdc42 GTP-Binding Protein; Cell Line, Tumor; Endothelins; Extracellular Matrix; Fluorescence Resonance Energy Transfer; Humans; Hydrolysis; Luminescent Proteins; Lysophospholipids; Melanoma; Microscopy, Confocal; Microscopy, Fluorescence; Neoplasm Proteins; Podosomes; rac1 GTP-Binding Protein; Receptors, G-Protein-Coupled; Receptors, Lysophosphatidic Acid; Recombinant Proteins; rhoA GTP-Binding Protein; RNA Interference; Time-Lapse Imaging

2016
Optotaxis: Caged Lysophosphatidic Acid Enables Optical Control of a Chemotactic Gradient.
    Cell chemical biology, 2016, 05-19, Volume: 23, Issue:5

    Topics: Animals; Calcium; Cell Line, Tumor; Cell Movement; Chemotaxis; HeLa Cells; Humans; Lasers; Lysophospholipids; Melanoma; Mice

2016
A rhodium(III)-based inhibitor of autotaxin with antiproliferative activity.
    Biochimica et biophysica acta. General subjects, 2017, Volume: 1861, Issue:2

    Topics: Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; Enzyme Inhibitors; Humans; Lysophospholipids; Melanoma; Multienzyme Complexes; NF-kappa B; Phosphodiesterase I; Phosphoric Diester Hydrolases; Rhodium; Signal Transduction; STAT3 Transcription Factor; Structure-Activity Relationship

2017
Autotaxin protects MCF-7 breast cancer and MDA-MB-435 melanoma cells against Taxol-induced apoptosis.
    Oncogene, 2009, Feb-19, Volume: 28, Issue:7

    Topics: Apoptosis; Blotting, Western; Breast Neoplasms; Cell Cycle; Cell Line, Tumor; Ceramides; Humans; Lysophosphatidylcholines; Lysophospholipids; Melanoma; Membrane Potential, Mitochondrial; Multienzyme Complexes; Paclitaxel; Phosphodiesterase I; Phosphoric Diester Hydrolases; Pyrophosphatases; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger

2009
Inhibition of autotaxin production or activity blocks lysophosphatidylcholine-induced migration of human breast cancer and melanoma cells.
    Molecular carcinogenesis, 2009, Volume: 48, Issue:9

    Topics: Anilides; Blotting, Western; Breast Neoplasms; Catalysis; Cell Line; Cell Line, Tumor; Cell Movement; Enzyme Inhibitors; Humans; Kinetics; Lysophosphatidylcholines; Lysophospholipids; Melanoma; Multienzyme Complexes; Organophosphates; Organophosphonates; Phosphodiesterase I; Phosphoric Diester Hydrolases; Pyridines; Pyrophosphatases; Receptors, Lysophosphatidic Acid; Reverse Transcriptase Polymerase Chain Reaction; RNA Interference; RNA, Small Interfering; Transfection

2009
Lysophosphatidic acid inhibits the cytotoxic activity of NK cells: involvement of Gs protein-mediated signaling.
    International immunology, 2009, Volume: 21, Issue:6

    Topics: Burkitt Lymphoma; Cell Line, Tumor; Class Ia Phosphatidylinositol 3-Kinase; Cyclic AMP-Dependent Protein Kinases; Cytotoxicity, Immunologic; Down-Regulation; GTP-Binding Protein alpha Subunits, Gi-Go; GTP-Binding Protein alpha Subunits, Gs; Humans; Immunologic Surveillance; Killer Cells, Natural; Lysophospholipids; Melanoma; p38 Mitogen-Activated Protein Kinases; Perforin; Phosphatidylinositol 3-Kinases; Receptors, Lysophosphatidic Acid; Signal Transduction; Tumor Escape

2009
Expression of sphingosine-1-phosphate receptors and lysophosphatidic acid receptors on cultured and xenografted human colon, breast, melanoma, and lung tumor cells.
    Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine, 2010, Volume: 31, Issue:4

    Topics: Animals; Breast Neoplasms; Colonic Neoplasms; Endothelium, Vascular; Female; Humans; Immunoenzyme Techniques; Lung Neoplasms; Lysophospholipids; Melanoma; Mice; Mice, SCID; Neoplasm Transplantation; Receptors, Lysophosphatidic Acid; Receptors, Lysosphingolipid; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Sphingosine; Transplantation, Heterologous; Tumor Cells, Cultured; Umbilical Cord

2010
Lysophosphatidic acid induces lymphangiogenesis and IL-8 production in vitro in human lymphatic endothelial cells.
    The American journal of pathology, 2012, Volume: 180, Issue:5

    Topics: Cell Movement; Cell Proliferation; Cell Survival; Cells, Cultured; Dose-Response Relationship, Drug; Endothelial Cells; Humans; Interleukin-8; Lymphangiogenesis; Lymphatic Metastasis; Lymphatic Vessels; Lysophospholipids; Melanoma; NF-kappa B; Receptors, Lysophosphatidic Acid; RNA, Small Interfering; Sentinel Lymph Node Biopsy; Signal Transduction; Up-Regulation

2012
Carba analogs of cyclic phosphatidic acid are selective inhibitors of autotaxin and cancer cell invasion and metastasis.
    The Journal of biological chemistry, 2006, Aug-11, Volume: 281, Issue:32

    Topics: Antineoplastic Agents; Cell Line, Tumor; Culture Media, Conditioned; Humans; Lipid Metabolism; Lysophospholipids; Melanoma; Multienzyme Complexes; Neoplasm Invasiveness; Neoplasm Metastasis; Phosphatidic Acids; Phosphodiesterase I; Phosphoric Diester Hydrolases; Pyrophosphatases; Recombinant Proteins; Spectrometry, Fluorescence

2006
Highly Potent Non-Carboxylic Acid Autotaxin Inhibitors Reduce Melanoma Metastasis and Chemotherapeutic Resistance of Breast Cancer Stem Cells.
    Journal of medicinal chemistry, 2017, 02-23, Volume: 60, Issue:4

    Topics: Animals; Antineoplastic Agents; Benzenesulfonamides; Breast Neoplasms; Cell Line, Tumor; Drug Resistance, Neoplasm; Female; Humans; Lung; Lung Neoplasms; Melanoma; Mice; Models, Molecular; Neoplasm Invasiveness; Neoplastic Stem Cells; Phosphodiesterase Inhibitors; Phosphoric Diester Hydrolases; Structure-Activity Relationship; Sulfonamides

2017