Compounds > lysophosphatidic acid
Page last updated: 2024-08-26

lysophosphatidic acid and MS (Multiple Sclerosis)

lysophosphatidic acid has been researched along with MS (Multiple Sclerosis) in 8 studies

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's5 (62.50)24.3611
2020's3 (37.50)2.80

Authors

AuthorsStudies
Chun, J; Hite, RK; Huang, XY; Kihara, Y; Liu, S; Liu, W; Paknejad, N; Ray, M; Zhu, L1
Aidinis, V; Aoki, J; Kaffe, E; Kollias, G; Magkrioti, C; Ninou, I; Panayotou, G; Sevastou, I; Stamatakis, G; Thivaios, S1
Chun, J; de Fonseca, FR; Estivill-Torrús, G; Fernández, O; Fransson, J; García-Díaz, B; Gómez-Conde, AI; Leyva, L; Louapre, C; Romero-Imbroda, J; Van-Evercooren, AB; Zujovic, V1
Brunkhorst, R; Geisslinger, G; Lerch, F; Lötsch, J; Schiffmann, S; Tegder, I; Thomas, D; Thrun, M; Ultsch, A1
Akahoshi, N; Araki, K; Araki, M; Gotoh, M; Ishii, S; Murakami-Murofushi, K; Neyama, H; Sumida, H; Tsukahara, R; Tsukahara, T; Ueda, H; Yamamoto, S; Yamamura, KI; Yanagida, K; Yoshikawa, K1
Balood, M; Harirchian, MH; Mesbah-Namin, SA; Siroos, B; Torbati, S; Zahednasab, H1
Chun, J; Kihara, Y; Mizuno, H1
Albright, RA; Braddock, DT; Cao, W; Chang, WC; De La Cruz, EM; Saunders, LP1

Reviews

1 review(s) available for lysophosphatidic acid and MS (Multiple Sclerosis)

ArticleYear
Lysophospholipid receptors in drug discovery.
    Experimental cell research, 2015, May-01, Volume: 333, Issue:2

    Topics: Animals; Drug Discovery; Humans; Lysophospholipids; Molecular Targeted Therapy; Multiple Sclerosis; Receptors, Lysophosphatidic Acid; Receptors, Lysosphingolipid; Signal Transduction; Sphingosine

2015

Other Studies

7 other study(ies) available for lysophosphatidic acid and MS (Multiple Sclerosis)

ArticleYear
Differential activation mechanisms of lipid GPCRs by lysophosphatidic acid and sphingosine 1-phosphate.
    Nature communications, 2022, 02-08, Volume: 13, Issue:1

    Topics: Animals; Azetidines; Benzyl Compounds; Cryoelectron Microscopy; GTP-Binding Protein alpha Subunits, Gi-Go; Humans; Lysophospholipids; Molecular Conformation; Molecular Docking Simulation; Multiple Sclerosis; Receptors, Lysophosphatidic Acid; Recombinant Proteins; Sf9 Cells; Single Molecule Imaging; Sphingosine; Sphingosine-1-Phosphate Receptors; Spodoptera

2022
Genetic deletion of Autotaxin from CD11b+ cells decreases the severity of experimental autoimmune encephalomyelitis.
    PloS one, 2020, Volume: 15, Issue:4

    Topics: Animals; CD11b Antigen; Central Nervous System; Encephalomyelitis, Autoimmune, Experimental; Gene Deletion; Gene Expression; Humans; Lysophospholipids; Macrophages; Mice; Microglia; Multiple Sclerosis; Phosphoric Diester Hydrolases; Signal Transduction; Spinal Cord

2020
Activation of Macrophages by Lysophosphatidic Acid through the Lysophosphatidic Acid Receptor 1 as a Novel Mechanism in Multiple Sclerosis Pathogenesis.
    Molecular neurobiology, 2021, Volume: 58, Issue:2

    Topics: Adolescent; Adult; Aged; Animals; Cell Polarity; Central Nervous System; Encephalomyelitis, Autoimmune, Experimental; Female; Humans; Inflammation; Lysophospholipids; Macrophage Activation; Macrophages; Mice, Inbred C57BL; Middle Aged; Monocytes; Multiple Sclerosis; Phenotype; PPAR gamma; Receptors, Lysophosphatidic Acid; Recurrence; Young Adult

2021
Machine-Learned Data Structures of Lipid Marker Serum Concentrations in Multiple Sclerosis Patients Differ from Those in Healthy Subjects.
    International journal of molecular sciences, 2017, Jun-07, Volume: 18, Issue:6

    Topics: Biomarkers; Case-Control Studies; Ceramides; Eicosanoids; Humans; Informatics; Lipid Metabolism; Lipids; Lysophospholipids; Machine Learning; Multiple Sclerosis

2017
LPA5 signaling is involved in multiple sclerosis-mediated neuropathic pain in the cuprizone mouse model.
    Journal of pharmacological sciences, 2018, Volume: 136, Issue:2

    Topics: Animals; Corpus Callosum; Cuprizone; Disease Models, Animal; Female; Gene Expression; Lysophospholipids; Male; Mice, Inbred Strains; Multiple Sclerosis; Neuralgia; Receptors, Lysophosphatidic Acid; Signal Transduction

2018
Elevated serum levels of lysophosphatidic acid in patients with multiple sclerosis.
    Human immunology, 2014, Volume: 75, Issue:5

    Topics: Adult; Female; Humans; Lysophospholipids; Male; Multiple Sclerosis; Multiple Sclerosis, Relapsing-Remitting

2014
Kinetic analysis of autotaxin reveals substrate-specific catalytic pathways and a mechanism for lysophosphatidic acid distribution.
    The Journal of biological chemistry, 2011, Aug-26, Volume: 286, Issue:34

    Topics: Amino Acid Substitution; Catalysis; Enzyme Inhibitors; Hydrolysis; Kinetics; Lysophospholipids; Multienzyme Complexes; Multiple Sclerosis; Mutation, Missense; Organophosphates; Phosphodiesterase I; Phosphoric Diester Hydrolases; Pyrophosphatases; Sphingosine; Substrate Specificity

2011