Page last updated: 2024-08-26

lysophosphatidic acid and Itching

lysophosphatidic acid has been researched along with Itching in 27 studies

Research

Studies (27)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (3.70)29.6817
2010's22 (81.48)24.3611
2020's4 (14.81)2.80

Authors

AuthorsStudies
Kittaka, H; Tominaga, M; Yamanoi, Y1
Kobayashi, K; Masuko, S; Matsushita, S; Murata, T; Shimizu, N; Yamamoto, M1
Levy, C; Trivella, J1
Düll, MM; Kremer, AE; Namer, B; Reeh, PW; Ries, V; Stengel, M; Strupf, M1
Adorini, L; Beuers, U; Bolier, R; Elferink, RO; Langedijk, JAGM; Lee, YT; Meurs, A; Tolenaars, D; van de Graaf, SFJ; Williamson, C1
Bergasa, NV1
Carrion, AF; Levy, C; Rosen, JD1
Esmaeili, A; Namazi, S1
Hegade, VS; Hussain, AB; Jones, DE; Reynolds, NJ; Samuel, R1
Beuers, U; Bolier, R; Oude Elferink, RP1
Ji, RR; Liu, T1
Aoki, J; Kimoto, S; Morikawa, Y; Okudaira, S; Shimizu, Y; Tanaka, T; Tokumura, A1
Bartz, C; Grünhage, F; Krawczyk, M; Lammert, F; Marschall, HU; Milkiewicz, M; Milkiewicz, P; Wunsch, E1
Hashimoto, T; Satoh, T1
Bowlus, CL; Evans, JF; Floreani, A; Gershwin, ME; Leung, PS; Nishio, Y; Qi, R; Sun, Y; Zhang, W; Zou, Z1
Barbier, O; Krawczyk, M; Kremer, AE; Lammert, F; Milkiewicz, M; Milkiewicz, P; Neurath, MF; Trottier, J; Wunsch, E1
Mittal, A1
Fukuta, N; Kittaka, H; Tominaga, M; Uchida, K1
Alhmada, Y; Haikel, Y; Hannig, M; Hassan, M; Hassan, SL; Megahed, M; Murad, F; Selimovic, D1
Beuers, U; Geenes, VL; Kondrackiene, J; Kremer, AE; Kuiper, EM; Kulik, W; Martens, JJ; Moolenaar, WH; Oude Elferink, RP; Prieto, J; Ruëff, F; Rust, C; van Buuren, HR; van Erpecum, KJ; Williamson, C1
Beuers, U; Kremer, AE; Oude Elferink, RP1
Beuers, UH; Kremer, AE; Martens, JJ; Oude Elferink, RP1
Drolz, A; Fuhrmann, V; Trauner, M1
Beuers, U; Kremer, AE; Maillette de Buy Wenniger, L; Oude Elferink, RP1
Bunchorntavakul, C; Reddy, KR1
Ikeda, H; Yatomi, Y1
Hashimoto, T; Momose, K; Ohata, H1

Reviews

13 review(s) available for lysophosphatidic acid and Itching

ArticleYear
Safety considerations for the management of cholestatic itch.
    Expert opinion on drug safety, 2021, Volume: 20, Issue:8

    Topics: Animals; Antipruritics; Cholestasis; Drug Development; Humans; Lysophospholipids; Phosphoric Diester Hydrolases; Pruritus

2021
Understanding and Treating Pruritus in Primary Biliary Cholangitis.
    Clinics in liver disease, 2018, Volume: 22, Issue:3

    Topics: Anion Exchange Resins; Bile Acids and Salts; Cholestyramine Resin; Drainage; Filtration; Humans; Liver Cirrhosis, Biliary; Lysophospholipids; Narcotic Antagonists; Opioid Peptides; Phosphoric Diester Hydrolases; Plasmapheresis; Pruritus; Receptors, Opioid; Rifampin; Selective Serotonin Reuptake Inhibitors; Serotonin; Sertraline; Substance P

2018
Pruritus secondary to primary biliary cholangitis: a review of the pathophysiology and management with phototherapy.
    The British journal of dermatology, 2019, Volume: 181, Issue:6

    Topics: Bile Acids and Salts; Humans; Liver Cirrhosis, Biliary; Lysophospholipids; Phosphoric Diester Hydrolases; Pruritus; Receptor, PAR-2; Renal Elimination; Signal Transduction; Skin; Therapies, Investigational; Treatment Outcome; Tryptases; Ultraviolet Therapy

2019
Advances in pathogenesis and treatment of pruritus.
    Clinics in liver disease, 2013, Volume: 17, Issue:2

    Topics: Animals; Anion Exchange Resins; Antibiotics, Antitubercular; Bile Acids and Salts; Cholestasis; Cholestyramine Resin; Humans; Lysophospholipids; Narcotic Antagonists; Pregnane X Receptor; Pruritus; Receptors, Steroid; Rifampin; Selective Serotonin Reuptake Inhibitors; Sertraline; Signal Transduction

2013
New insights into the mechanisms of itch: are pain and itch controlled by distinct mechanisms?
    Pflugers Archiv : European journal of physiology, 2013, Volume: 465, Issue:12

    Topics: Animals; Brain; Chronic Disease; Humans; Lysophospholipids; Neuronal Plasticity; Pain; Perception; Pruritus; Receptors, G-Protein-Coupled; Sensory Receptor Cells; Serotonin; Spinal Cord; Synaptic Transmission; Toll-Like Receptors

2013
Autotaxin, Pruritus and Primary Biliary Cholangitis (PBC).
    Autoimmunity reviews, 2016, Volume: 15, Issue:8

    Topics: Animals; Biosynthetic Pathways; Cholangitis; Humans; Lysophospholipids; Phosphoric Diester Hydrolases; Pruritus

2016
Cholestatic Itch Management.
    Current problems in dermatology, 2016, Volume: 50

    Topics: Anion Exchange Resins; Cholagogues and Choleretics; Cholestasis; Cholestyramine Resin; Humans; Lysophospholipids; Naltrexone; Narcotic Antagonists; Plasmapheresis; Pregnane X Receptor; Pruritus; Receptors, Steroid; Rifampin; Selective Serotonin Reuptake Inhibitors; Sertraline; Ultraviolet Therapy; Ursodeoxycholic Acid

2016
Hepatitis C virus-associated pruritus: Etiopathogenesis and therapeutic strategies.
    World journal of gastroenterology, 2017, Feb-07, Volume: 23, Issue:5

    Topics: Cholestasis; Cytokines; Hepatitis C, Chronic; Humans; Lysophospholipids; Phosphoric Diester Hydrolases; Pruritus

2017
Mediators of pruritus during cholestasis.
    Current opinion in gastroenterology, 2011, Volume: 27, Issue:3

    Topics: Animals; Bile Acids and Salts; Cholestasis; Disease Models, Animal; Humans; Lysophospholipids; Mice; Multienzyme Complexes; Phosphodiesterase I; Phosphoric Diester Hydrolases; Pruritus; Pyrophosphatases; Signal Transduction

2011
Extracorporeal artificial liver support systems in the management of intractable cholestatic pruritus.
    Liver international : official journal of the International Association for the Study of the Liver, 2011, Volume: 31 Suppl 3

    Topics: Cholestasis; Cholestyramine Resin; Humans; Lysophospholipids; Opioid Peptides; Plasmapheresis; Pruritus; Renal Dialysis; Rifampin; Sertraline; Sorption Detoxification; Ursodeoxycholic Acid

2011
[Pruritus in liver disease. Pathogenesis and treatment].
    Nederlands tijdschrift voor geneeskunde, 2011, Volume: 155, Issue:52

    Topics: Anticholesteremic Agents; Cholestasis; Humans; Liver Diseases; Lysophospholipids; Pruritus

2011
Pruritus in chronic cholestatic liver disease.
    Clinics in liver disease, 2012, Volume: 16, Issue:2

    Topics: Algorithms; Anion Exchange Resins; Antipruritics; Bile Acids and Salts; Cholestasis; Chronic Disease; Female; Histamine Antagonists; Humans; Liver Diseases; Liver Transplantation; Lysophospholipids; Narcotic Antagonists; Opioid Peptides; Phosphoric Diester Hydrolases; Plasmapheresis; Pregnancy; Pregnancy Complications; Pregnane X Receptor; Pruritus; Receptors, Steroid; Selective Serotonin Reuptake Inhibitors; Serotonin; Serotonin Antagonists; Signal Transduction

2012
Autotaxin in liver fibrosis.
    Clinica chimica acta; international journal of clinical chemistry, 2012, Nov-20, Volume: 413, Issue:23-24

    Topics: Carcinoma, Hepatocellular; Hepatic Stellate Cells; Humans; Liver Cirrhosis; Lysophospholipids; Phosphoric Diester Hydrolases; Pruritus

2012

Other Studies

14 other study(ies) available for lysophosphatidic acid and Itching

ArticleYear
Cheek Injection Model for Simultaneous Measurement of Pain and Itch-related Behaviors.
    Journal of visualized experiments : JoVE, 2019, 09-27, Issue:151

    Topics: Animals; Antipruritics; Behavior, Animal; Capsaicin; Cheek; Disease Models, Animal; Injections; Lysophospholipids; Male; Mice; Mice, Inbred C57BL; Pain; Pruritus

2019
Automated detection of mouse scratching behaviour using convolutional recurrent neural network.
    Scientific reports, 2021, 01-12, Volume: 11, Issue:1

    Topics: Animals; Behavior, Animal; Dermatitis, Atopic; Disease Models, Animal; Female; Lysophospholipids; Male; Mice; Mice, Inbred BALB C; Neural Networks, Computer; Pruritus

2021
Lysophosphatidic acid activates nociceptors and causes pain or itch depending on the application mode in human skin.
    Pain, 2022, 03-01, Volume: 163, Issue:3

    Topics: Animals; Histamine; Humans; Lysophospholipids; Nerve Fibers, Unmyelinated; Neuralgia; Nociceptors; Pruritus; Skin

2022
Inhibition of autotaxin by bile salts and bile salt-like molecules increases its expression by feedback regulation.
    Biochimica et biophysica acta. Molecular basis of disease, 2021, 11-01, Volume: 1867, Issue:11

    Topics: Bile Acids and Salts; Drainage; Enzyme Assays; Feedback, Physiological; Humans; Liver Cirrhosis, Biliary; Lysophospholipids; Phosphoric Diester Hydrolases; Pruritus; Receptors, Lysophosphatidic Acid

2021
The pruritus of cholestasis: From bile acids to opiate agonists: Relevant after all these years.
    Medical hypotheses, 2018, Volume: 110

    Topics: Animals; Anticholesteremic Agents; Bile Acids and Salts; Chenodeoxycholic Acid; Cholestasis; Humans; Lysophospholipids; Models, Biological; Opioid Peptides; Pruritus; Receptors, G-Protein-Coupled; Receptors, Opioid

2018
Is melatonin effective for pruritus caused by liver disease?
    Medical hypotheses, 2018, Volume: 121

    Topics: Animals; Cholestasis; Dermatitis, Atopic; Humans; Liver Diseases; Lysophospholipids; Melatonin; Mice; Phosphoric Diester Hydrolases; Pruritus; Rats

2018
Potentials of the circulating pruritogenic mediator lysophosphatidic acid in development of allergic skin inflammation in mice: role of blood cell-associated lysophospholipase D activity of autotaxin.
    The American journal of pathology, 2014, Volume: 184, Issue:5

    Topics: Animals; Blood Cells; Cell Membrane; Chromatography, Liquid; Hypersensitivity; Inflammation; Lysophospholipids; Male; Mass Spectrometry; Mice; Mice, Inbred BALB C; Phosphoric Diester Hydrolases; Protein Binding; Pruritus; Skin; Solubility; Sphingosine

2014
Variant adiponutrin confers genetic protection against cholestatic itch.
    Scientific reports, 2014, Oct-09, Volume: 4

    Topics: Adult; Aged; Aged, 80 and over; Alleles; Cholestasis, Intrahepatic; Female; Genetic Association Studies; Genetic Predisposition to Disease; Genotype; Humans; Lipase; Liver; Lysophospholipids; Membrane Proteins; Middle Aged; Pregnancy; Pregnancy Complications; Pruritus

2014
Generalized pruritus in primary sclerosing cholangitis: implications of histamine release by lysophosphatidic acid.
    The British journal of dermatology, 2015, Volume: 173, Issue:5

    Topics: Adolescent; Cholangitis, Sclerosing; Histamine H1 Antagonists, Non-Sedating; Histamine Release; Humans; Lysophospholipids; Male; Pruritus; Terfenadine

2015
Serum Autotaxin is a Marker of the Severity of Liver Injury and Overall Survival in Patients with Cholestatic Liver Diseases.
    Scientific reports, 2016, 08-10, Volume: 6

    Topics: Adult; Aged; Biomarkers; Cholangitis, Sclerosing; Cholestasis; Cross-Sectional Studies; Female; Humans; Liver Cirrhosis, Biliary; Lysophospholipids; Male; Middle Aged; Phosphoric Diester Hydrolases; Prognosis; Proportional Hazards Models; Prospective Studies; Pruritus; Quality of Life; Severity of Illness Index; Survival Analysis; Young Adult

2016
Lysophosphatidic acid-induced itch is mediated by signalling of LPA
    The Journal of physiology, 2017, 04-15, Volume: 595, Issue:8

    Topics: Animals; HEK293 Cells; Humans; Lysophospholipids; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Phospholipase D; Pruritus; Receptors, Lysophosphatidic Acid; Signal Transduction; Transient Receptor Potential Channels; TRPA1 Cation Channel; TRPV Cation Channels

2017
Lysophosphatidic acid is a potential mediator of cholestatic pruritus.
    Gastroenterology, 2010, Volume: 139, Issue:3

    Topics: Adult; Aged; Animals; Calcium; Cell Line, Tumor; Cholestasis, Intrahepatic; Chromatography, High Pressure Liquid; Disease Models, Animal; Drainage; Female; Fluorometry; Humans; Injections, Intradermal; Liver Cirrhosis, Biliary; Lysophospholipids; Male; Mass Spectrometry; Mice; Mice, Inbred C57BL; Middle Aged; Multienzyme Complexes; Neurons; Phosphodiesterase I; Phosphoric Diester Hydrolases; Pregnancy; Pregnancy Complications; Pruritus; Pyrophosphatases; Severity of Illness Index; Time Factors; Up-Regulation

2010
The molecular mechanism of cholestatic pruritus.
    Digestive diseases (Basel, Switzerland), 2011, Volume: 29, Issue:1

    Topics: Animals; Calcium Signaling; Case-Control Studies; Cell Line, Tumor; Cholestasis; Cholestasis, Intrahepatic; Disease Models, Animal; Female; Humans; Lysophospholipids; Mice; Multienzyme Complexes; Phosphodiesterase I; Phosphoric Diester Hydrolases; Pregnancy; Pregnancy Complications; Pruritus; Pyrophosphatases

2011
Itch-scratch responses induced by lysophosphatidic acid in mice.
    Pharmacology, 2004, Volume: 72, Issue:1

    Topics: Amides; Animals; Antipruritics; Capsaicin; Injections, Intradermal; Intracellular Signaling Peptides and Proteins; Ketotifen; Lysophospholipids; Mice; Mice, Inbred ICR; Protein Serine-Threonine Kinases; Pruritus; Pyridines; Rats; rho-Associated Kinases

2004