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lysophosphatidic acid and Innate Inflammatory Response

lysophosphatidic acid has been researched along with Innate Inflammatory Response in 71 studies

Research

Studies (71)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's13 (18.31)29.6817
2010's46 (64.79)24.3611
2020's12 (16.90)2.80

Authors

AuthorsStudies
Guo, F; Guo, Z; Huang, L; Li, Y; Qian, W; Xu, Y; Yin, Y; Zhu, W1
Fan, G; Gao, M; Jia, Y; Li, Y; Suo, X; Yang, X; Zong, Y1
Ban, KY; Jun, HS; Kim, D; Lee, GH1
Jiang, S; Li, M; Yang, H1
Ueda, H1
Bernhart, E; Joshi, L; Koyani, CN; Malle, E; Plastira, I; Reicher, H; Sattler, W; Strohmaier, H1
Kraemer, M; Morris, AJ; Smyth, SS; Van Hoose, P; Yang, L1
Brindley, DN; Hemmings, DG1
Ayata, CK; Das, S; Diaz, OE; Doñas, C; Franc, Y; Geier, F; Hernández, PP; Hruz, P; Kaya, B; Kaymak, T; Melhem, H; Morales, RA; Niess, JH; Villablanca, EJ; Wuggenig, P1
Chun, J; de Fonseca, FR; Estivill-Torrús, G; Fernández, O; Fransson, J; García-Díaz, B; Gómez-Conde, AI; Leyva, L; Louapre, C; Romero-Imbroda, J; Van-Evercooren, AB; Zujovic, V1
Abdel-Latif, A; Abo-Aly, M; Al-Darraji, A; Chelvarajan, L; Gao, E; Hernandez, G; Levitan, BM; Morris, AJ; Peng, H; R Donahue, R; Shokri, E; Smyth, SS; Tripathi, H1
Mathew, D; Torres, RM1
Kamato, D; Little, PJ; Xu, S; Zhou, Y1
Bascands, JL; Casemayou, A; Denis, C; Faguer, S; Gilet, M; Goudounéche, D; Marsal, D; Mirzoyan, K; Saulnier-Blache, JS; Schanstra, JP1
Aoki, T; Hiyama, H; Kiso, T; Murai, N; Oka, H; Sekizawa, T; Watabiki, T1
Cenac, C; Chicanne, G; Gaits-Iacovoni, F; Gratacap, MP; Le Faouder, P; Minville, V; Mujalli, A; Payrastre, B; Severin, S; Vardon Bounes, F1
Benesch, MGK; Brindley, DN; Meng, G; Tang, X; Yang, Z1
González-Arenas, A; Valdés-Rives, SA1
Berger, R; Hankemeier, T; Harms, AC; Schoeman, JC; van Weeghel, M; Vreeken, RJ1
Guo, T; Li, F; Shen, X; Zhang, T; Zou, J1
Atsumi, GI; Inoue, K; Kudo, I; Murakami, M; Nakatani, Y1
Cook, KE; Fabiilli, ML; Nelson, DL; Zhao, Y1
Brindley, DN; Curtis, JM; McMullen, TPW; Meng, G; Tang, X; Yang, Z; Zhao, Y1
Chew, WS; Chun, J; Hay, NWJ; Herr, DR; Hind, T; Lee, JHM; Lim, SM; Ong, WY; Rivera, R; Srikanth, M1
Denning, TL; El-Rayes, B; Guo, L; Haque, A; He, P; Lin, S; Moolenaar, WH; Raeman, R; Yun, CC1
Brandon, JA; Halder, S; Kraemer, M; Morris, AJ; Smyth, SS; Ubele, M; Vandra, J1
Chen, QY; Deng, SJ; Dong, YL; Duan, XY; Fan, H; Liu, YJ; Nan, Z; Wu, H; Xu, M1
Morris, AJ; Smyth, SS1
Ackerman, SJ; Aidinis, V; Berdyshev, E; Christman, JW; Chun, J; Chung, S; Corbridge, SJ; Deng, J; Du, J; Fu, P; Gorshkova, IA; Jaffe, HA; Jarjour, NN; Kaffe, E; Karpurapu, M; Kelly, EA; Lee, YG; Li, Y; Morris, AJ; Natarajan, V; Ninou, I; Nyenhuis, S; Park, GY; Prestwich, GD; Ranjan, R; Smyth, SS; Xiao, L1
Anantharamaiah, GM; Buga, GM; Chattopadhyay, A; Danciger, JS; Farias-Eisner, R; Fogelman, AM; Gao, F; Grijalva, V; Hough, G; Lusis, AJ; Meriwether, D; Navab, M; Org, E; Pan, C; Reddy, ST; Smyth, SS; Su, F; Van Lenten, BJ; Wagner, AC1
Georas, SN1
Georas, SN; Knowlden, S1
Brandon, J; Escalante-Alcalde, D; Miriyala, S; Morris, AJ; Panchatcharam, M; Patil, P; Salous, AK; Smyth, SS; Sunkara, M; Wheeler, J1
Getz, GS; Reardon, CA1
Aoki, J; Kimoto, S; Morikawa, Y; Okudaira, S; Shimizu, Y; Tanaka, T; Tokumura, A1
Alnouti, Y; Bathena, SP; Cerutis, DR; Headen, KV; McVaney, TP; Miyamoto, T; Nunn, ME; Ogunleye, AO; Weston, MD1
Benesch, MG; Brindley, DN; Curtis, JM; McMullen, TP; Zhao, YY1
Bourgoin, SG; Davis, L; Fernandes, MJ; Poubelle, PE; Sardella, A; Zhao, C1
Flower, RJ; Gobbetti, T; Kusters, DH; McArthur, S; Perretti, M; Reutelingsperger, CP1
Exley, M; Lange, M; Nowak-Machen, M; Robson, SC; Usheva, A; Wu, S1
Ackerman, SJ; Berdyshev, E; Christman, JW; Natarajan, V; Nyenhuis, S; Park, GY1
Arola, L; Caimari, A; Calder, PC; Childs, CE; Del Bas, JM; Miles, EA; Paras Chavez, C; Rodriguez-Naranjo, MI; West, AL1
Brindley, DN; Curtis, JM; Tang, X; Wang, X; Zhao, YY1
Aoki, J; Kaibuchi, K; Kawana, H; Kiyama, H; Konishi, H; Makide, K; Nakamuta, S; Ohwada, T; Tokizane, K1
Aoki, J; Aozasa, K; Bai, Z; Fujita, N; Fukui, Y; Hayasaka, H; Hirosawa, M; Jin, S; Miyasaka, M; Nakasaki, T; Okudaira, S; Otani, K; Ozono, K; Tanaka, T; Tsuruo, T; Umemoto, E1
Aoki, J; Arima, N; Kano, K; Kitamura, H; Makide, K1
Barbolina, MV; Burkhalter, RJ; Forgacs, G; Hudson, LG; Liu, Y; Marga, F; Moss, NM; Stack, MS; Westfall, SD1
Liu, S; Mills, GB; Murph, M; Panupinthu, N1
Anantharamaiah, GM; Fogelman, AM; Hama, S; Hough, G; Imaizumi, S; Navab, M; Reddy, ST1
Bourgoin, SG; Chun, J; Fernandes, MJ; Poubelle, PE; Sardella, A; Zhao, C1
Murakami, M; Sato, H; Taketomi, Y; Yamamoto, K1
Berdyshev, E; Chun, J; He, D; Natarajan, V; Su, Y; Zhao, J; Zhao, Y1
Awada, R; Bourdon, E; Grès, S; Lefebvre d'Hellencourt, C; Rondeau, P; Saulnier-Blache, JS1
Balys, M; Chapman, TJ; Emo, J; Georas, SN; Meednu, N; Randall, T; Rangasamy, T; Rezaee, F1
Adamski, J; Berg, K; Björkbacka, H; Edsfeldt, A; Gonçalves, I; Grufman, H; Ko, NY; Nilsson, J; Nilsson, M; Nitulescu, M; Persson, A; Prehn, C1
Natarajan, V; Zhao, Y1
Crombie, D; Currie, PD; Ellett, F; Frisca, F; Goldshmit, Y; Lieschke, GJ; Matteo, R; Moreno, K; Pébay, A; Sabbadini, RA; Sztal, T1
Aidinis, V; Kaffe, E; Mouratis, MA; Sevastou, I1
Hayashi, Y; Inoue, K; Nakanishi, H; Peters, C; Sun, L; Tsuda, M; Wu, Z1
Czimmerer, Z; Nagy, L; Nemet, I; Poliska, S; Szanto, A; Varga, T1
Biessen, EA; Bot, I; Bot, M; de Jager, SC; Heeren, RM; Kuiper, J; Lagraauw, HM; MacAleese, L; Quax, PH; van Berkel, TJ1
Brown, JH; Cho, MK; Dusaban, SS; Masliah, E; Purcell, NH; Rockenstein, E; Smrcka, AV1
Cummings, R; Garcia, JG; He, D; Jacoby, D; Natarajan, V; Ohba, M; Saatian, B; Spannhake, EW; Watkins, T; Zhao, Y1
Chikumi, H; Kadowaki, S; Sato, K; Shimizu, E; Yamamoto, H; Yamasaki, A; Yoneda, K1
Bhagat, A; Kuypers, FA; Larkin, SK; Neidlinger, NA; Victorino, GP1
Barbaz, D; Bard, H; Bkaily, G; Brault, S; Checchin, D; Chemtob, S; Chorvatova, A; D'Orléans-Juste, P; Fortier, A; Geha, A; Gobeil, F; Goetzl, EJ; Gratton, JP; Heveker, N; Hou, X; Nader, M; Peri, K; Ribeiro-da-Silva, A; Vazquez-Tello, A; Zhu, T1
Barekzi, E; Georas, S; Hise, K; Roman, J; Steinke, JW1
Malbon, CC; Shumay, E; Tao, J; Wang, HY1
Baldini, PM; Carotenuto, F; Chiurchiu', V; D'Aquilio, F; Di Nardo, P; Giambra, V; Izzi, V; Procaccini, M1
Genetos, DC; Karin, NJ; Tan, R; Verma, S; Waters, KM; Yellowley, CE1
Chang, KJ; Chen, CN; Hsieh, FJ; Lee, H; Lin, CI; Lin, PW1

Reviews

18 review(s) available for lysophosphatidic acid and Innate Inflammatory Response

ArticleYear
Emerging Roles of Lysophosphatidic Acid in Macrophages and Inflammatory Diseases.
    International journal of molecular sciences, 2023, Aug-07, Volume: 24, Issue:15

    Topics: Humans; Inflammation; Lysophospholipids; Macrophages; Receptors, Lysophosphatidic Acid

2023
Systems Pathology of Neuropathic Pain and Fibromyalgia.
    Biological & pharmaceutical bulletin, 2019, Volume: 42, Issue:11

    Topics: Animals; Chronic Pain; Fibromyalgia; Inflammation; Lysophospholipids; Mice; Neuralgia; Receptors, Lysophosphatidic Acid; Signal Transduction

2019
Roles for lysophosphatidic acid signaling in vascular development and disease.
    Biochimica et biophysica acta. Molecular and cell biology of lipids, 2020, Volume: 1865, Issue:8

    Topics: Cardiovascular Diseases; Humans; Inflammation; Lysophospholipids; Molecular Structure; Muscle, Smooth, Vascular; Phosphatidate Phosphatase; Signal Transduction

2020
Signalling by lysophosphatidate and its health implications.
    Essays in biochemistry, 2020, 09-23, Volume: 64, Issue:3

    Topics: Animals; Cardiovascular Diseases; Female; Humans; Idiopathic Pulmonary Fibrosis; Inflammation; Lysophospholipids; Neoplasms; Phosphatidate Phosphatase; Phosphoric Diester Hydrolases; Pregnancy; Pregnancy Complications; Receptors, G-Protein-Coupled; Signal Transduction; Wound Healing

2020
Lysophosphatidic Acid Is an Inflammatory Lipid Exploited by Cancers for Immune Evasion
    Frontiers in immunology, 2020, Volume: 11

    Topics: Animals; CD8-Positive T-Lymphocytes; CTLA-4 Antigen; Humans; Inflammation; Lysophospholipids; Neoplasm Proteins; Neoplasms; Programmed Cell Death 1 Receptor; Receptors, Lysophosphatidic Acid; Signal Transduction; Tumor Escape

2020
The importance of blood platelet lipid signaling in thrombosis and in sepsis.
    Advances in biological regulation, 2018, Volume: 67

    Topics: Animals; Blood Platelets; Humans; Inflammation; Lipid Metabolism; Lysophospholipids; Phosphatidylinositol 3-Kinases; Signal Transduction; Sphingosine; Thrombosis; Type C Phospholipases

2018
Lysophosphatidate Signaling: The Tumor Microenvironment's New Nemesis.
    Trends in cancer, 2017, Volume: 3, Issue:11

    Topics: Drug Resistance, Neoplasm; Humans; Inflammation; Lysophospholipids; Multienzyme Complexes; Mutation; Neoplasms; Phosphodiesterase I; Signal Transduction; Tumor Microenvironment

2017
Autotaxin-Lysophosphatidic Acid: From Inflammation to Cancer Development.
    Mediators of inflammation, 2017, Volume: 2017

    Topics: Humans; Inflammation; Lysophospholipids; Neoplasms; Phosphoric Diester Hydrolases; Receptors, Lysophosphatidic Acid; Signal Transduction

2017
Regulatory Functions of Phospholipase A2.
    Critical reviews in immunology, 2017, Volume: 37, Issue:2-6

    Topics: Animals; Arachidonic Acid; Dietary Fats; Eicosanoids; Gene Expression Regulation, Enzymologic; Humans; Inflammation; Isoenzymes; Lysophospholipids; Phospholipases A2, Calcium-Independent; Phospholipases A2, Cytosolic; Phospholipases A2, Secretory; Phospholipids; Protein Conformation; Receptors, Phospholipase A2; Signal Transduction

2017
The autotaxin-LPA axis emerges as a novel regulator of lymphocyte homing and inflammation.
    Journal of immunology (Baltimore, Md. : 1950), 2014, Feb-01, Volume: 192, Issue:3

    Topics: Adaptive Immunity; Airway Remodeling; Animals; Antigens; Asthma; Cell Movement; Chemotaxis, Leukocyte; Dendritic Cells; Humans; Inflammation; Isoxazoles; Lymphoid Tissue; Lysophospholipids; Mice; Phosphoric Diester Hydrolases; Propionates; Radiation Chimera; Receptors, Lysophosphatidic Acid; Signal Transduction; T-Lymphocytes; Up-Regulation; Venules

2014
The structure/function of apoprotein A-I mimetic peptides: an update.
    Current opinion in endocrinology, diabetes, and obesity, 2014, Volume: 21, Issue:2

    Topics: Anti-Inflammatory Agents; Antioxidants; Apolipoprotein A-I; Atherosclerosis; Biomimetic Materials; Diet; Female; Humans; Inflammation; Intestine, Small; Lysophospholipids; Male; Plants, Genetically Modified; Solanum lycopersicum; Structure-Activity Relationship

2014
Polyunsaturated lysophosphatidic acid as a potential asthma biomarker.
    Biomarkers in medicine, 2016, Volume: 10, Issue:2

    Topics: Adult; Airway Remodeling; Allergens; Animals; Asthma; Biomarkers; Bronchoalveolar Lavage Fluid; Disease Models, Animal; Humans; Inflammation; Lung; Lysophosphatidylcholines; Lysophospholipids; Mice; Phospholipases A1; Phosphoric Diester Hydrolases; Receptors, Lysophosphatidic Acid

2016
[Lysophospholipid mediators].
    Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme, 2009, Volume: 54, Issue:1

    Topics: Animals; Cell Physiological Phenomena; Drug Design; Fingolimod Hydrochloride; Humans; Immunosuppressive Agents; Inflammation; Insulin; Insulin Secretion; Lysophospholipids; Neurotransmitter Agents; Propylene Glycols; Receptors, G-Protein-Coupled; Sphingosine

2009
Microenvironmental regulation of ovarian cancer metastasis.
    Cancer treatment and research, 2009, Volume: 149

    Topics: Ascites; Cadherins; Carcinoma; Cell Adhesion; Cell Dedifferentiation; Cell Differentiation; Cell Transformation, Neoplastic; Cytokines; Epithelial Cells; Extracellular Matrix; Female; Fibroblasts; Humans; Inflammation; Integrins; Intercellular Signaling Peptides and Proteins; Lysophospholipids; Neoplasm Proteins; Ovarian Neoplasms; Peptide Hydrolases; Peritoneal Neoplasms; Phenotype

2009
ATX-LPA receptor axis in inflammation and cancer.
    Cell cycle (Georgetown, Tex.), 2009, Nov-15, Volume: 8, Issue:22

    Topics: Animals; Breast Neoplasms; Female; Inflammation; Lysophospholipids; Mice; Mice, Transgenic; Models, Biological; Multienzyme Complexes; Phosphodiesterase I; Phosphoric Diester Hydrolases; Pyrophosphatases; Receptors, Lysophosphatidic Acid; Signal Transduction

2009
Secreted phospholipase A2 revisited.
    Journal of biochemistry, 2011, Volume: 150, Issue:3

    Topics: Animals; Arthritis; Catalysis; Glycerophospholipids; Group II Phospholipases A2; Heart Injuries; Humans; Inflammation; Lysophospholipids; Metabolic Syndrome; Mice; Neoplasms; Phospholipases A2; Phospholipids; Respiratory Distress Syndrome; Signal Transduction

2011
Lysophosphatidic acid (LPA) and its receptors: role in airway inflammation and remodeling.
    Biochimica et biophysica acta, 2013, Volume: 1831, Issue:1

    Topics: Airway Remodeling; Animals; Humans; Inflammation; Lung; Lysophospholipids; Receptors, Lysophosphatidic Acid

2013
Lysoglycerophospholipids in chronic inflammatory disorders: the PLA(2)/LPC and ATX/LPA axes.
    Biochimica et biophysica acta, 2013, Volume: 1831, Issue:1

    Topics: Animals; Chronic Disease; Humans; Inflammation; Lysophosphatidylcholines; Lysophospholipids; Phospholipases A2; Phosphoric Diester Hydrolases; Signal Transduction

2013

Trials

1 trial(s) available for lysophosphatidic acid and Innate Inflammatory Response

ArticleYear
Impairment of lysophospholipid metabolism in obesity: altered plasma profile and desensitization to the modulatory properties of n-3 polyunsaturated fatty acids in a randomized controlled trial.
    The American journal of clinical nutrition, 2016, Volume: 104, Issue:2

    Topics: Adult; Diet, High-Fat; Dietary Fats; Fatty Acids, Omega-3; Fatty Liver; Female; Hep G2 Cells; Humans; Inflammation; Insulin Resistance; Lysophospholipids; Male; Middle Aged; Obesity

2016

Other Studies

52 other study(ies) available for lysophosphatidic acid and Innate Inflammatory Response

ArticleYear
Mesenteric Adipose Tissue Contributes to Intestinal Fibrosis in Crohn's Disease Through the ATX-LPA Axis.
    Journal of Crohn's & colitis, 2022, Aug-04, Volume: 16, Issue:7

    Topics: Adipose Tissue; Animals; Colon; Crohn Disease; Fibrosis; Inflammation; Lysophospholipids; Mice

2022
GPAT3 regulates the synthesis of lipid intermediate LPA and exacerbates Kupffer cell inflammation mediated by the ERK signaling pathway.
    Cell death & disease, 2023, 03-24, Volume: 14, Issue:3

    Topics: Acyltransferases; Humans; Inflammation; Kupffer Cells; Liver; Liver Diseases; Lysophospholipids; Protein Kinases; Signal Transduction

2023
Lysophosphatidic Acid Induces Podocyte Pyroptosis in Diabetic Nephropathy by an Increase of Egr1 Expression via Downregulation of EzH2.
    International journal of molecular sciences, 2023, Jun-09, Volume: 24, Issue:12

    Topics: Animals; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Down-Regulation; Early Growth Response Protein 1; Enhancer of Zeste Homolog 2 Protein; Histones; Inflammasomes; Inflammation; Mice; NLR Family, Pyrin Domain-Containing 3 Protein; Podocytes; Pyroptosis

2023
MAPK signaling determines lysophosphatidic acid (LPA)-induced inflammation in microglia.
    Journal of neuroinflammation, 2020, Apr-23, Volume: 17, Issue:1

    Topics: Animals; Inflammation; Lysophospholipids; MAP Kinase Signaling System; Mice; Mice, Inbred C57BL; Microglia; Phosphoric Diester Hydrolases; Receptors, Lysophosphatidic Acid

2020
Lysophosphatidic Acid-Mediated GPR35 Signaling in CX3CR1
    Cell reports, 2020, 08-04, Volume: 32, Issue:5

    Topics: Animals; Colitis; CX3C Chemokine Receptor 1; Dextran Sulfate; Gastrointestinal Microbiome; Gene Deletion; Homeostasis; Humans; Inflammation; Inflammatory Bowel Diseases; Intestines; Lysophospholipids; Macrophages; Mice, Inbred C57BL; Phosphoric Diester Hydrolases; Receptors, G-Protein-Coupled; Signal Transduction; Tumor Necrosis Factor-alpha; Zebrafish; Zebrafish Proteins

2020
Activation of Macrophages by Lysophosphatidic Acid through the Lysophosphatidic Acid Receptor 1 as a Novel Mechanism in Multiple Sclerosis Pathogenesis.
    Molecular neurobiology, 2021, Volume: 58, Issue:2

    Topics: Adolescent; Adult; Aged; Animals; Cell Polarity; Central Nervous System; Encephalomyelitis, Autoimmune, Experimental; Female; Humans; Inflammation; Lysophospholipids; Macrophage Activation; Macrophages; Mice, Inbred C57BL; Middle Aged; Monocytes; Multiple Sclerosis; Phenotype; PPAR gamma; Receptors, Lysophosphatidic Acid; Recurrence; Young Adult

2021
Autotaxin inhibition reduces cardiac inflammation and mitigates adverse cardiac remodeling after myocardial infarction.
    Journal of molecular and cellular cardiology, 2020, Volume: 149

    Topics: Animals; Benzoxazoles; Cell Count; Cell Movement; Female; Gene Deletion; Humans; Inflammation; Interferon-alpha; Interferon-beta; Lysophospholipids; Macrophages; Male; Mice, Inbred C57BL; Middle Aged; Myelopoiesis; Myocardial Infarction; Myocardium; Phosphatidate Phosphatase; Phosphoric Diester Hydrolases; Piperazines; Recovery of Function; Up-Regulation; Vascular Remodeling; Wound Healing

2020
Curcumin Inhibits Lysophosphatidic Acid Mediated MCP-1 Expression via Blocking ROCK Signalling.
    Molecules (Basel, Switzerland), 2021, Apr-16, Volume: 26, Issue:8

    Topics: Animals; Blotting, Western; Cell Line; Cell Survival; Chemokine CCL2; Curcumin; Humans; Inflammation; Lysophospholipids; Muscle, Smooth, Vascular; Receptors, Transforming Growth Factor beta; rho-Associated Kinases; Signal Transduction

2021
Lysophosphatidic Acid Protects Against Endotoxin-Induced Acute Kidney Injury.
    Inflammation, 2017, Volume: 40, Issue:5

    Topics: Acute Kidney Injury; Animals; Blood Urea Nitrogen; Creatinine; Cytokines; Endotoxins; Inflammation; Lipopolysaccharides; Lysophospholipids; Mice; Mice, Inbred C57BL; Protective Agents; RAW 264.7 Cells

2017
Analgesic effects of novel lysophosphatidic acid receptor 5 antagonist AS2717638 in rodents.
    Neuropharmacology, 2017, Volume: 126

    Topics: Analgesics; Animals; Benzoxazoles; Cells, Cultured; Cyclic AMP; Female; Hyperalgesia; Inflammation; Injections, Spinal; Isoquinolines; Lysophospholipids; Male; Mice, Inbred C57BL; Mice, Knockout; Neuralgia; Pain; Pain Threshold; Piperidines; Polyisoprenyl Phosphates; Rats, Inbred Lew; Rats, Sprague-Dawley; Receptors, Lysophosphatidic Acid

2017
Development and application of a UHPLC-MS/MS metabolomics based comprehensive systemic and tissue-specific screening method for inflammatory, oxidative and nitrosative stress.
    Analytical and bioanalytical chemistry, 2018, Volume: 410, Issue:10

    Topics: Animals; Chromatography, High Pressure Liquid; Fatty Acids; Humans; Inflammation; Isoprostanes; Lysophospholipids; Male; Metabolome; Metabolomics; Mice, Inbred C57BL; Nitrosative Stress; Oxidative Stress; Tandem Mass Spectrometry

2018
Lysophosphatidic acid enhances neointimal hyperplasia following vascular injury through modulating proliferation, autophagy, inflammation and oxidative stress.
    Molecular medicine reports, 2018, Volume: 18, Issue:1

    Topics: Animals; Atherosclerosis; Cell Proliferation; Hyperplasia; Inflammation; Lysophospholipids; Male; Neointima; Oxidative Stress; Rats; Rats, Sprague-Dawley

2018
In vitro evaluation of lysophosphatidic acid delivery via reverse perfluorocarbon emulsions to enhance alveolar epithelial repair.
    Colloids and surfaces. B, Biointerfaces, 2018, 09-01, Volume: 169

    Topics: Alveolar Epithelial Cells; Animals; Anti-Bacterial Agents; Cell Movement; Cell Proliferation; Cells, Cultured; Drug Delivery Systems; Emulsions; Fluorocarbons; Inflammation; Lysophospholipids; Mice; Particle Size; Surface Properties

2018
Dexamethasone decreases the autotaxin-lysophosphatidate-inflammatory axis in adipose tissue: implications for the metabolic syndrome and breast cancer.
    FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2019, Volume: 33, Issue:2

    Topics: Adipose Tissue; Animals; Dexamethasone; Female; Humans; Inflammation; Lysophospholipids; Mammary Neoplasms, Experimental; Metabolic Syndrome; Mice; Mice, Inbred BALB C; Neoplasm Proteins; Phosphoric Diester Hydrolases; Signal Transduction

2019
Lysophosphatidic acid and its receptor LPA
    European journal of pharmacology, 2018, Dec-15, Volume: 841

    Topics: Animals; Carrageenan; Facial Pain; Inflammation; Lysophospholipids; Male; Mice; Mice, Inbred C57BL; Pain; Receptors, Lysophosphatidic Acid; Signal Transduction

2018
Autotaxin determines colitis severity in mice and is secreted by B cells in the colon.
    FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2019, Volume: 33, Issue:3

    Topics: Animals; B-Lymphocytes; Cell Line, Tumor; Cell Movement; Colitis; Colon; HCT116 Cells; Humans; Inflammation; Lymphocytes; Lysophospholipids; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Phosphoric Diester Hydrolases; Receptors, Lysophosphatidic Acid; Signal Transduction

2019
Adipose-derived autotaxin regulates inflammation and steatosis associated with diet-induced obesity.
    PloS one, 2019, Volume: 14, Issue:2

    Topics: Adipocytes; Adipose Tissue; Adiposity; Animals; Diet, High-Fat; Dietary Fats; Inflammation; Lysophospholipids; Mice; Mice, Inbred C57BL; Obesity; Phosphoric Diester Hydrolases; Triglycerides

2019
Autotaxin-Lysophosphatidic Acid Axis Blockade Improves Inflammation by Regulating Th17 Cell Differentiation in DSS-Induced Chronic Colitis Mice.
    Inflammation, 2019, Volume: 42, Issue:5

    Topics: Animals; Cell Differentiation; Chronic Disease; Colitis; Dextran Sulfate; Disease Models, Animal; Enzyme Inhibitors; Inflammation; Lysophospholipids; Mice; Phosphoric Diester Hydrolases; Th17 Cells

2019
Lysophosphatidic acid and cardiovascular disease: seeing is believing.
    Journal of lipid research, 2013, Volume: 54, Issue:5

    Topics: Animals; Inflammation; Lysophospholipids; Mast Cells; Plaque, Atherosclerotic

2013
Autotaxin production of lysophosphatidic acid mediates allergic asthmatic inflammation.
    American journal of respiratory and critical care medicine, 2013, Oct-15, Volume: 188, Issue:8

    Topics: Allergens; Animals; Asthma; Bronchoalveolar Lavage Fluid; Disease Models, Animal; Humans; Inflammation; Lysophospholipids; Male; Mice; Mice, Transgenic; Phosphoric Diester Hydrolases; Signal Transduction

2013
Transgenic 6F tomatoes act on the small intestine to prevent systemic inflammation and dyslipidemia caused by Western diet and intestinally derived lysophosphatidic acid.
    Journal of lipid research, 2013, Volume: 54, Issue:12

    Topics: Animals; Apolipoprotein A-I; Diet; Dyslipidemias; Female; Gene Expression Regulation; Inflammation; Intestine, Small; Lysophospholipids; Mice; Peptidomimetics; Plants, Genetically Modified; Receptors, LDL; Solanum lycopersicum; Western World

2013
Allergic to autotaxin. A new role for lysophospholipase d and lysophosphatidic Acid in asthma?
    American journal of respiratory and critical care medicine, 2013, Oct-15, Volume: 188, Issue:8

    Topics: Animals; Asthma; Humans; Inflammation; Lysophospholipids; Male; Phosphoric Diester Hydrolases

2013
Mice with targeted inactivation of ppap2b in endothelial and hematopoietic cells display enhanced vascular inflammation and permeability.
    Arteriosclerosis, thrombosis, and vascular biology, 2014, Volume: 34, Issue:4

    Topics: Animals; Capillary Permeability; Cytokines; Endothelial Cells; Genotype; Hematopoietic Stem Cells; Inflammation; Inflammation Mediators; Integrases; Lysophospholipids; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Phenotype; Phosphatidate Phosphatase; Phosphoric Diester Hydrolases; Promoter Regions, Genetic; Receptor, TIE-2; Receptors, Lysophosphatidic Acid; Signal Transduction; Transgenes

2014
Potentials of the circulating pruritogenic mediator lysophosphatidic acid in development of allergic skin inflammation in mice: role of blood cell-associated lysophospholipase D activity of autotaxin.
    The American journal of pathology, 2014, Volume: 184, Issue:5

    Topics: Animals; Blood Cells; Cell Membrane; Chromatography, Liquid; Hypersensitivity; Inflammation; Lysophospholipids; Male; Mass Spectrometry; Mice; Mice, Inbred BALB C; Phosphoric Diester Hydrolases; Protein Binding; Pruritus; Skin; Solubility; Sphingosine

2014
A Major Human Oral Lysophosphatidic Acid Species, LPA 18:1, Regulates Novel Genes in Human Gingival Fibroblasts.
    Journal of periodontology, 2015, Volume: 86, Issue:5

    Topics: Adult; Cells, Cultured; Female; Fibroblasts; Gene Expression Regulation; Gingiva; Gingival Crevicular Fluid; Humans; Inflammation; Inflammation Mediators; Interleukin-11; Interleukin-6; Interleukin-8; Lysophospholipids; Male; Phosphoric Diester Hydrolases; Saliva; Signal Transduction; Suppressor of Cytokine Signaling Proteins; Transcription, Genetic

2015
Regulation of autotaxin expression and secretion by lysophosphatidate and sphingosine 1-phosphate.
    Journal of lipid research, 2015, Volume: 56, Issue:6

    Topics: Adipose Tissue; Animals; Carbolines; Gene Expression Regulation; Humans; Inflammation; Lysophospholipids; Mice; Phosphoric Diester Hydrolases; Receptors, G-Protein-Coupled; Sphingosine; Tumor Necrosis Factor-alpha; Wound Healing

2015
A transgenic mouse model for the in vivo bioluminescence imaging of the expression of the lysophosphatidic acid receptor 3: relevance for inflammation and uterine physiology research.
    Transgenic research, 2015, Volume: 24, Issue:4

    Topics: Animals; Cells, Cultured; Disease Models, Animal; Female; Fluorescent Antibody Technique, Indirect; Humans; Image Processing, Computer-Assisted; Inflammation; Luciferases; Luminescent Measurements; Lysophospholipids; Male; Mice; Mice, Transgenic; Promoter Regions, Genetic; Real-Time Polymerase Chain Reaction; Receptors, Lysophosphatidic Acid; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Up-Regulation; Uterus

2015
Definition of a Novel Pathway Centered on Lysophosphatidic Acid To Recruit Monocytes during the Resolution Phase of Tissue Inflammation.
    Journal of immunology (Baltimore, Md. : 1950), 2015, Aug-01, Volume: 195, Issue:3

    Topics: Actin Cytoskeleton; Animals; Annexin A1; Apoptosis; Cells, Cultured; Enzyme Activation; Humans; Inflammation; Lipopolysaccharide Receptors; Lysophospholipids; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Monocytes; Neutrophils; p38 Mitogen-Activated Protein Kinases; Phospholipases A2, Calcium-Independent; Receptors, Formyl Peptide; Receptors, IgG; Receptors, Lysophosphatidic Acid; RNA Interference; RNA, Small Interfering; Zymosan

2015
Lysophosphatidic acid generation by pulmonary NKT cell ENPP-2/autotaxin exacerbates hyperoxic lung injury.
    Purinergic signalling, 2015, Volume: 11, Issue:4

    Topics: Acute Lung Injury; Animals; Cell Count; Hyperoxia; Inflammation; Lung; Lysophosphatidylcholines; Lysophospholipids; Mice; Mice, Inbred C57BL; Natural Killer T-Cells; Oxygen; Phosphoric Diester Hydrolases; Receptors, Purinergic P2X7; Up-Regulation

2015
Doxycycline attenuates breast cancer related inflammation by decreasing plasma lysophosphatidate concentrations and inhibiting NF-κB activation.
    Molecular cancer, 2017, 02-08, Volume: 16, Issue:1

    Topics: Animals; Breast Neoplasms; Cell Line, Tumor; Cytokines; Disease Models, Animal; Doxycycline; Female; Humans; Inflammation; Inflammation Mediators; Lysophospholipids; Macrophages; Mice; Neovascularization, Pathologic; NF-kappa B; Phosphorylation; Protein Transport; Tumor Burden; Xenograft Model Antitumor Assays

2017
Phospholipid localization implies microglial morphology and function via Cdc42 in vitro.
    Glia, 2017, Volume: 65, Issue:5

    Topics: Animals; Animals, Newborn; cdc42 GTP-Binding Protein; Cell Membrane; Cells, Cultured; Inflammation; Lysophospholipids; Mice, Knockout; Microglia; NF-kappa B; Phenotype

2017
Involvement of the lysophosphatidic acid-generating enzyme autotaxin in lymphocyte-endothelial cell interactions.
    The American journal of pathology, 2008, Volume: 173, Issue:5

    Topics: Animals; Cell Communication; Cell Movement; Cells, Cultured; Chemokine CCL21; Chemokine CXCL13; Chronic Disease; Cytoskeleton; Endothelial Cells; GTPase-Activating Proteins; Guanine Nucleotide Exchange Factors; Inflammation; Lymph Nodes; Lymphocytes; Lysophospholipids; Mice; Mice, Inbred C57BL; Multienzyme Complexes; Myeloid Differentiation Factor 88; Peyer's Patches; Phosphodiesterase I; Phosphoric Diester Hydrolases; Pyrophosphatases; Receptors, Lysophosphatidic Acid; Signal Transduction; Up-Regulation

2008
Intestine may be a major site of action for the apoA-I mimetic peptide 4F whether administered subcutaneously or orally.
    Journal of lipid research, 2011, Volume: 52, Issue:6

    Topics: Administration, Cutaneous; Administration, Oral; Amino Acid Sequence; Animals; Apolipoprotein A-I; Apolipoproteins E; Atherosclerosis; Diet; Disease Models, Animal; Dose-Response Relationship, Drug; Feces; Female; Gene Deletion; Inflammation; Intestinal Mucosa; Lipoproteins, HDL; Liver; Lysophospholipids; Mice; Mice, Knockout; Molecular Mimicry; Molecular Sequence Data; Peptides; Serum Amyloid A Protein

2011
TNF-alpha promotes LPA1- and LPA3-mediated recruitment of leukocytes in vivo through CXCR2 ligand chemokines.
    Journal of lipid research, 2011, Volume: 52, Issue:7

    Topics: Animals; Chemokines; Dose-Response Relationship, Drug; Female; Gene Knockout Techniques; Inflammation; Leukocytes; Ligands; Lysophospholipids; Mice; Organothiophosphates; Phosphatidic Acids; Receptors, Interleukin-8B; Receptors, Lysophosphatidic Acid; Time Factors; Tumor Necrosis Factor-alpha

2011
Lysophosphatidic acid receptor 1 modulates lipopolysaccharide-induced inflammation in alveolar epithelial cells and murine lungs.
    American journal of physiology. Lung cellular and molecular physiology, 2011, Volume: 301, Issue:4

    Topics: Animals; Bronchi; Bronchoalveolar Lavage Fluid; Cells, Cultured; Epithelial Cells; Gene Expression Regulation; Inflammation; Interleukin-6; Interleukin-8; Isoxazoles; Lipopolysaccharide Receptors; Lipopolysaccharides; Lysophospholipids; Male; Membrane Microdomains; Mice; Mice, Knockout; NF-kappa B; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Propionates; Pulmonary Alveoli; Receptor Cross-Talk; Receptors, Lysophosphatidic Acid; Signal Transduction

2011
Autotaxin protects microglial cells against oxidative stress.
    Free radical biology & medicine, 2012, Jan-15, Volume: 52, Issue:2

    Topics: Animals; Catalase; Cytoprotection; Gene Expression; Hydrogen Peroxide; Inflammation; Lysophospholipids; Mice; Microglia; Nitric Oxide Synthase Type II; Oxidants; Oxidation-Reduction; Oxidative Stress; Phosphoric Diester Hydrolases; Proteasome Endopeptidase Complex; Protein Carbonylation; Recombinant Proteins; Superoxide Dismutase

2012
Lpa2 is a negative regulator of both dendritic cell activation and murine models of allergic lung inflammation.
    Journal of immunology (Baltimore, Md. : 1950), 2012, Apr-15, Volume: 188, Issue:8

    Topics: Administration, Inhalation; Adoptive Transfer; Allergens; Animals; Asthma; Dendritic Cells; Disease Models, Animal; Female; Gene Deletion; HEK293 Cells; Humans; Inflammation; Lung; Lysophospholipids; Mice; Mice, Inbred C57BL; Mice, Knockout; NF-kappa B; Receptors, Lysophosphatidic Acid; Signal Transduction; Transcription, Genetic

2012
Evidence supporting a key role of Lp-PLA2-generated lysophosphatidylcholine in human atherosclerotic plaque inflammation.
    Arteriosclerosis, thrombosis, and vascular biology, 2012, Volume: 32, Issue:6

    Topics: 1-Alkyl-2-acetylglycerophosphocholine Esterase; Aged; Biomarkers; Biopsy; Carotid Stenosis; Cytokines; Enzyme-Linked Immunosorbent Assay; Female; Humans; Immunohistochemistry; Inflammation; Inflammation Mediators; Lysophosphatidylcholines; Lysophospholipids; Macrophages; Male; Mass Spectrometry; Middle Aged; Muscle, Smooth, Vascular; Phospholipases A2; Plaque, Atherosclerotic; Severity of Illness Index; T-Lymphocytes

2012
Blockage of lysophosphatidic acid signaling improves spinal cord injury outcomes.
    The American journal of pathology, 2012, Volume: 181, Issue:3

    Topics: Animals; Antibodies, Monoclonal; Apoptosis; Cell Death; Cell Proliferation; Cell Survival; CHO Cells; Cricetinae; Disease Models, Animal; Enzyme-Linked Immunosorbent Assay; Humans; Inflammation; Lysophospholipids; Mice; Microglia; Motor Activity; Neurites; Neuroprotective Agents; Receptors, Lysophosphatidic Acid; Recovery of Function; Signal Transduction; Spinal Cord Injuries; Zebrafish

2012
Microglial cathepsin B contributes to the initiation of peripheral inflammation-induced chronic pain.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2012, Aug-15, Volume: 32, Issue:33

    Topics: Adenosine Triphosphate; Amino Acid Chloromethyl Ketones; Analysis of Variance; Animals; Calcium-Binding Proteins; Carrier Proteins; Cathepsin B; CD11b Antigen; CD4 Antigens; Cells, Cultured; Chromogranin A; Chronic Pain; Cyclooxygenase 2; Dipeptides; Disease Models, Animal; Dose-Response Relationship, Drug; Enzyme Inhibitors; Freund's Adjuvant; Functional Laterality; Ganglia, Spinal; Gene Expression Regulation; Hyperalgesia; Inflammation; Interleukin-18; Interleukin-1beta; Lysophospholipids; Lysosomes; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Microfilament Proteins; Microglia; Motor Activity; Nerve Tissue Proteins; NLR Family, Pyrin Domain-Containing 3 Protein; Pain Threshold; RNA, Small Interfering; Spinal Cord; Transfection

2012
Identification of novel markers of alternative activation and potential endogenous PPARγ ligand production mechanisms in human IL-4 stimulated differentiating macrophages.
    Immunobiology, 2012, Volume: 217, Issue:12

    Topics: Adaptor Proteins, Signal Transducing; Antigens, CD; Arachidonate 15-Lipoxygenase; Biomarkers; Cell Differentiation; Cells, Cultured; Gene Expression; Gene Expression Profiling; Humans; Hydroxyeicosatetraenoic Acids; Inflammation; Interferon-gamma; Interleukin-4; Ligands; Linoleic Acids; Lipid Metabolism; Lysophospholipids; Macrophage Activation; Macrophages; Membrane Proteins; Monoamine Oxidase; Phosphoric Diester Hydrolases; PPAR gamma; Proto-Oncogene Proteins pp60(c-src); Reactive Oxygen Species; Transcription Factors; Transcriptional Activation; Tumor Necrosis Factor-alpha

2012
Lysophosphatidic acid triggers mast cell-driven atherosclerotic plaque destabilization by increasing vascular inflammation.
    Journal of lipid research, 2013, Volume: 54, Issue:5

    Topics: Animals; Apoptosis; Carotid Arteries; Cells, Cultured; Cromolyn Sodium; Inflammation; Lysophospholipids; Macrophages; Mast Cells; Mice; Plaque, Atherosclerotic; Radiography; Tryptases

2013
Phospholipase C epsilon links G protein-coupled receptor activation to inflammatory astrocytic responses.
    Proceedings of the National Academy of Sciences of the United States of America, 2013, Feb-26, Volume: 110, Issue:9

    Topics: Animals; Astrocytes; Cyclooxygenase 2; Enzyme Activation; Inflammation; Lysophospholipids; Mice; Mice, Inbred C57BL; Mice, Knockout; Models, Biological; NF-kappa B; Phosphoinositide Phospholipase C; Protein Kinase C; Receptors, G-Protein-Coupled; Sphingosine; Thrombin; Wound Healing

2013
Protein kinase Cdelta mediates lysophosphatidic acid-induced NF-kappaB activation and interleukin-8 secretion in human bronchial epithelial cells.
    The Journal of biological chemistry, 2004, Sep-24, Volume: 279, Issue:39

    Topics: Acetophenones; Active Transport, Cell Nucleus; Animals; Benzopyrans; Blotting, Western; Bronchoalveolar Lavage; Cell Nucleus; Cells, Cultured; Chemokine CXCL2; Chemokines; Cytokines; DNA, Complementary; Dose-Response Relationship, Drug; Electrophoresis, Polyacrylamide Gel; Gene Expression Regulation; Humans; Inflammation; Interleukin-8; Luciferases; Lysophospholipids; Macrophages; Mice; Mice, Inbred C57BL; Microscopy, Fluorescence; NF-kappa B; Oligonucleotide Array Sequence Analysis; Phosphorylation; Protein Isoforms; Protein Kinase C; Protein Kinase C-delta; Protein Transport; Receptor, Platelet-Derived Growth Factor beta; RNA; Signal Transduction; Time Factors; Transcriptional Activation; Transfection

2004
Down-regulation of inducible nitric oxide synthase by lysophosphatidic acid in human respiratory epithelial cells.
    Molecular and cellular biochemistry, 2004, Volume: 262, Issue:1-2

    Topics: Cell Line; Cytokines; Down-Regulation; Epithelial Cells; Gene Expression Regulation, Enzymologic; Humans; Inflammation; Lysophospholipids; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Regeneration; Respiratory System; rho GTP-Binding Proteins; Signal Transduction

2004
Hydrolysis of phosphatidylserine-exposing red blood cells by secretory phospholipase A2 generates lysophosphatidic acid and results in vascular dysfunction.
    The Journal of biological chemistry, 2006, Jan-13, Volume: 281, Issue:2

    Topics: Animals; Cell Line; Cells, Cultured; Dose-Response Relationship, Drug; Endothelium, Vascular; Erythrocytes; Group II Phospholipases A2; Hemolysis; Humans; Hydrolysis; Inflammation; Lipids; Lysophospholipids; Palmitates; Phosphatidic Acids; Phosphatidylserines; Phospholipases A; Phospholipases A2; Phosphoserine; Rats; Time Factors; Umbilical Veins

2006
Nitric oxide signaling via nuclearized endothelial nitric-oxide synthase modulates expression of the immediate early genes iNOS and mPGES-1.
    The Journal of biological chemistry, 2006, Jun-09, Volume: 281, Issue:23

    Topics: Animals; Base Sequence; Cell Nucleus; Cells, Cultured; DNA Primers; Gene Expression; Genes, Immediate-Early; Guanylate Cyclase; Humans; Inflammation; Liver; Lysophospholipids; Microscopy, Confocal; Nitric Oxide; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Prostaglandin-E Synthases; Prostaglandin-Endoperoxide Synthases; Rats; Receptors, Cytoplasmic and Nuclear; Receptors, Lysophosphatidic Acid; Reverse Transcriptase Polymerase Chain Reaction; Signal Transduction; Soluble Guanylyl Cyclase; Swine

2006
Lysophosphatidic acid stimulates inflammatory cascade in airway epithelial cells.
    Prostaglandins, leukotrienes, and essential fatty acids, 2006, Volume: 74, Issue:6

    Topics: Cell Proliferation; Cells, Cultured; Chemokines; Cytokines; Enzyme-Linked Immunosorbent Assay; Epithelial Cells; Gene Expression Regulation; Humans; Inflammation; Lung; Lysophospholipids; Nasal Mucosa; Nasal Polyps; Receptors, Lysophosphatidic Acid

2006
Lysophosphatidic acid regulates trafficking of beta2-adrenergic receptors: the Galpha13/p115RhoGEF/JNK pathway stimulates receptor internalization.
    The Journal of biological chemistry, 2007, Jul-20, Volume: 282, Issue:29

    Topics: Cell Line, Tumor; Cell Membrane; Genes, Dominant; GTP-Binding Protein alpha Subunits, G12-G13; Guanine Nucleotide Exchange Factors; Humans; Inflammation; Lysophospholipids; MAP Kinase Kinase 4; Microscopy, Confocal; Models, Biological; Protein Transport; Receptors, Adrenergic, beta-2; Rho Guanine Nucleotide Exchange Factors; rhoA GTP-Binding Protein; Signal Transduction

2007
Activatory properties of lysophosphatidic acid on human THP-1 cells.
    Inflammation, 2007, Volume: 30, Issue:5

    Topics: Arachidonic Acid; Cell Line; Cell Proliferation; Dinoprostone; DNA Replication; Enzyme Activation; Humans; Inflammation; Inflammation Mediators; Isoxazoles; Leukotriene B4; Lysophospholipids; Monocytes; NADPH Oxidases; Propionates; Reactive Oxygen Species; Receptors, Lysophosphatidic Acid; RNA, Messenger; Time Factors; Up-Regulation

2007
DNA microarray analysis reveals a role for lysophosphatidic acid in the regulation of anti-inflammatory genes in MC3T3-E1 cells.
    Bone, 2007, Volume: 41, Issue:5

    Topics: 3T3 Cells; Animals; Base Sequence; DNA Primers; Gene Expression Regulation; Inflammation; Kinetics; Lysophospholipids; Mice; Oligonucleotide Array Sequence Analysis; Reverse Transcriptase Polymerase Chain Reaction

2007
Lysophosphatidic acid regulates inflammation-related genes in human endothelial cells through LPA1 and LPA3.
    Biochemical and biophysical research communications, 2007, Nov-30, Volume: 363, Issue:4

    Topics: Cell Adhesion; Cells, Cultured; Chemokine CCL2; Endothelial Cells; Gene Expression Regulation; Humans; Inflammation; Intercellular Adhesion Molecule-1; Interleukin-1; Interleukin-8; Lysophospholipids; Peptide Fragments; Receptors, Lysophosphatidic Acid; RNA, Small Interfering

2007