lysophosphatidic acid and Disease Models, Animal

Topics: Animals; Asthma; Cell Movement; Dendritic Cells; Disease Models, Animal; Endothelial Cells; Endothelium, Vascular; Gene Knock-In Techniques; Humans; Lung; Lymph Nodes; Lysophospholipids; Macrophages, Alveolar; Mice; Mice, Knockout; Phosphoric Diester Hydrolases; Receptors, Lysophosphatidic Acid; Signal Transduction; Th2 Cells

Topics: Adult; Airway Remodeling; Allergens; Animals; Asthma; Biomarkers; Bronchoalveolar Lavage Fluid; Disease Models, Animal; Humans; Inflammation; Lung; Lysophosphatidylcholines; Lysophospholipids; Mice; Phospholipases A1; Phosphoric Diester Hydrolases; Receptors, Lysophosphatidic Acid

Topics: Animals; Bile Acids and Salts; Cholestasis; Disease Models, Animal; Humans; Lysophospholipids; Mice; Multienzyme Complexes; Phosphodiesterase I; Phosphoric Diester Hydrolases; Pruritus; Pyrophosphatases; Signal Transduction

Topics: Animals; Antiviral Agents; Artificial Intelligence; Chlorocebus aethiops; Disease Models, Animal; Drug Evaluation, Preclinical; High-Throughput Screening Assays; Immunocompetence; Inhibitory Concentration 50; Methacycline; Mice, Inbred C57BL; Protease Inhibitors; Quantitative Structure-Activity Relationship; Small Molecule Libraries; Vero Cells; Zika Virus; Zika Virus Infection

Topics: Animals; Anti-Bacterial Agents; Azoxymethane; Bacteria; Bacterial Translocation; Cell Proliferation; Cell Transformation, Neoplastic; Colon; Colorectal Neoplasms; Diet, High-Fat; Disease Models, Animal; Dysbiosis; Fecal Microbiota Transplantation; Feces; Gastrointestinal Microbiome; Genes, APC; Germ-Free Life; Humans; Lysophospholipids; Male; Mice, Inbred BALB C; Mice, Inbred C57BL; Mice, Transgenic; Permeability; Tumor Cells, Cultured

Topics: Adult; Animals; Cells, Cultured; Disease Models, Animal; Endometrium; Endothelial Cells; Enzyme Activation; Epithelial Cells; Female; Humans; Lysophospholipids; Matrix Metalloproteinase 3; Matrix Metalloproteinase 9; Mice, Inbred C57BL; Neovascularization, Physiologic; Signal Transduction; Tumor Necrosis Factor-alpha; Wounds and Injuries

Topics: Allergens; Animals; Asthma; Carotid Body; Disease Models, Animal; Lysophospholipids; Male; Rats; Rats, Inbred BN; Rats, Sprague-Dawley

Topics: Alzheimer Disease; Amyloid beta-Protein Precursor; Animals; Brain; Disease Models, Animal; Fatty Acids, Unsaturated; Hippocampus; Humans; Lipids; Lysophospholipids; Male; Mice, Transgenic; Phospholipids; Presenilin-1; Signal Transduction; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Sphingosine; tau Proteins

Topics: Animals; Arthralgia; Arthritis, Experimental; Disease Models, Animal; Female; Hyperalgesia; Injections, Intra-Articular; Knee Joint; Lysophospholipids; Male; Neuralgia; Pain Threshold; Rats; Rats, Wistar

Topics: Animals; Capillary Permeability; Disease Models, Animal; Endothelial Cells; Ischemic Stroke; Lysophospholipids; Mice; Phosphoric Diester Hydrolases; Reperfusion

Topics: Animals; Asthma; Bronchoalveolar Lavage Fluid; Cytokines; Disease Models, Animal; Lung; Lysophospholipids; Mice; Mice, Inbred BALB C; Mucins; Ovalbumin

Topics: Animals; Depression; Disease Models, Animal; Fluorescein; Lupus Erythematosus, Systemic; Lupus Vasculitis, Central Nervous System; Mice; Mice, Inbred MRL lpr; Microglia

Topics: Animals; Cell Movement; Cell Proliferation; Cells, Cultured; Disease Models, Animal; Hyperplasia; Mice; Myocytes, Smooth Muscle; Neointima; Phenotype

Topics: Animals; Annexin A5; Disease Models, Animal; Female; Humans; Infusions, Intravenous; Intestinal Mucosa; Kidney; Lung; Lysophospholipids; Organ Dysfunction Scores; Phosphatidylserines; Rats; Resuscitation; Shock, Hemorrhagic; Treatment Outcome

Topics: Animals; Atherosclerosis; Cell Movement; Disease Models, Animal; Down-Regulation; Foam Cells; Fucosyltransferases; HEK293 Cells; Hepatocyte Nuclear Factor 1-alpha; Humans; Lysophospholipids; Macrophage Activation; Male; Mice; Mice, Inbred C57BL; Mice, Knockout, ApoE; Protein Processing, Post-Translational; RAW 264.7 Cells; Receptors, Lysophosphatidic Acid; Signal Transduction

Topics: Animals; Antipruritics; Behavior, Animal; Capsaicin; Cheek; Disease Models, Animal; Injections; Lysophospholipids; Male; Mice; Mice, Inbred C57BL; Pain; Pruritus

Topics: Animals; Animals, Newborn; Apoptosis; Brain; Calcium-Binding Proteins; Disease Models, Animal; Ependyma; Ependymoglial Cells; Infant, Premature, Diseases; Isoxazoles; Lysophospholipids; Macrophages; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Microfilament Proteins; Phagocytosis; Propionates; Receptors, Lysophosphatidic Acid

Topics: Animals; Cauda Equina; Constriction, Pathologic; Disease Models, Animal; Female; Gene Expression Regulation; Lysophosphatidylcholines; Lysophospholipids; Neuralgia; Rats, Sprague-Dawley; Receptors, Lysophosphatidic Acid; RNA, Messenger; Spinal Cord

Topics: Acute Lung Injury; Animals; Anti-Inflammatory Agents; Biomarkers; Chromatography, High Pressure Liquid; Cytokines; Disease Models, Animal; Fatty Acids, Volatile; Ganoderma; Histidine; Lysophosphatidylcholines; Lysophospholipids; Male; Metabolomics; Polysaccharides; Rats; Rats, Sprague-Dawley; Signal Transduction; Tandem Mass Spectrometry; Taurocholic Acid; Tryptophan

Topics: Animals; Cell Death; Cerebral Cortex; Cerebral Veins; Cerebrovascular Circulation; Disease Models, Animal; Infarction, Middle Cerebral Artery; Lysophospholipids; Male; Microcirculation; Oxygen; Oxygen Consumption; Rats, Inbred F344; Reperfusion Injury

Topics: Animals; Disease Models, Animal; Enterocytes; Lysophospholipids; Malabsorption Syndromes; Mice; Mice, Knockout; Microvilli; Mucolipidoses; Myosin Type V; Sodium-Glucose Transporter 1

Topics: Allergens; Animals; Asthma; Bronchial Hyperreactivity; Cell Differentiation; Cytokines; Disease Models, Animal; Enzyme-Linked Immunosorbent Assay; Female; Lysophospholipids; Macrophages; Mice; Plethysmography; Pyroglyphidae; Receptors, Lysophosphatidic Acid; Th2 Cells

Topics: Animals; Blood-Brain Barrier; Capillary Permeability; Cerebral Cortex; Disease Models, Animal; Infarction, Middle Cerebral Artery; Lysophospholipids; Male; Phosphorylation; Proto-Oncogene Proteins c-akt; Rats, Inbred F344; Reperfusion; Reperfusion Injury; Ribosomal Protein S6 Kinases

Topics: Anemia, Hemolytic; Animals; Cell Differentiation; Cell Lineage; Disease Models, Animal; Erythroid Cells; Erythropoiesis; Gene Expression Regulation; Humans; Isoquinolines; K562 Cells; Lysophospholipids; Male; Mice; Mice, Inbred BALB C; Myeloid Cells; Organothiophosphates; Phenylhydrazines; Phosphatidic Acids; Receptors, Lysophosphatidic Acid; Stem Cells

Topics: Animals; Behavior, Animal; Dermatitis, Atopic; Disease Models, Animal; Female; Lysophospholipids; Male; Mice; Mice, Inbred BALB C; Neural Networks, Computer; Pruritus

Topics: Animals; Behavior, Animal; Carbolines; Cerebrospinal Fluid; Disease Models, Animal; Female; Ganglia, Spinal; Humans; Lysophosphatidylcholines; Lysophospholipids; Mice; Neuralgia; Phosphodiesterase Inhibitors; Phosphoric Diester Hydrolases; Rats, Sprague-Dawley; Spinal Canal; Spinal Stenosis

Topics: Animals; Caco-2 Cells; Cell Line; Colitis; Dextran Sulfate; Disease Models, Animal; Humans; Intestinal Mucosa; Lysophospholipids; Male; Mice; Permeability; Receptors, Lysophosphatidic Acid

Topics: Animals; Cell Differentiation; Cells, Cultured; Dibenzazepines; Disease Models, Animal; Enterocytes; Humans; Intestinal Mucosa; Jejunum; Lysophospholipids; Malabsorption Syndromes; Mice; Mice, Knockout; Microvilli; Mucolipidoses; Myosin Type V; Organoids; Primary Cell Culture; Receptors, Notch; Stem Cells; Wnt Signaling Pathway

Topics: Animals; Cell Death; Disease Models, Animal; Female; Forkhead Box Protein O3; Gene Expression Regulation; Hair Cells, Auditory, Outer; Hearing; Hearing Loss, Noise-Induced; Homozygote; Lysophospholipids; Male; Mice, Knockout; Noise; Phosphoric Diester Hydrolases; Time Factors

Topics: Administration, Intranasal; Animals; Antibodies; Brain; Brain Injuries, Traumatic; Disease Models, Animal; Hyperalgesia; Lysophospholipids; Male; Pain Measurement; Rats; Rats, Sprague-Dawley

Topics: Animals; Cell Differentiation; Cell Line; Connective Tissue Growth Factor; Disease Models, Animal; Extracellular Matrix; Fibroblasts; Fibrosis; Focal Adhesion Kinase 1; Integrin alphaV; Lysophospholipids; Mice; Mice, Inbred C57BL; Mice, Inbred mdx; Muscle, Skeletal; Muscular Dystrophy, Duchenne; Myoblasts; Phosphorylation; Signal Transduction

Topics: Animals; Corpus Callosum; Cuprizone; Disease Models, Animal; Female; Gene Expression; Lysophospholipids; Male; Mice, Inbred Strains; Multiple Sclerosis; Neuralgia; Receptors, Lysophosphatidic Acid; Signal Transduction

Topics: Animals; Astrocytes; Cells, Cultured; Central Nervous System Agents; Cerebral Cortex; Disease Models, Animal; Glutamic Acid; Humans; Ketamine; Lysophospholipids; Mental Disorders; Mice, Inbred C57BL; Mice, Transgenic; Neural Inhibition; Phosphoric Diester Hydrolases; Proteoglycans; Psychotropic Drugs; Synapses; Tissue Culture Techniques; Vesicular Transport Proteins

Topics: 2-Aminoadipic Acid; Animals; Animals, Newborn; Astrocytes; Cells, Cultured; Chemokine CXCL1; Disease Models, Animal; Dose-Response Relationship, Drug; Glial Fibrillary Acidic Protein; Lysophospholipids; Male; Mice; Mice, Inbred C57BL; Neuralgia; Pain Measurement; Pain Threshold; Pyridines; RNA, Messenger; Sciatic Neuropathy; Spinal Cord; Up-Regulation

Topics: Activating Transcription Factor 3; Aniline Compounds; Animals; Arthralgia; Disease Models, Animal; Exploratory Behavior; Female; Furans; Hyperalgesia; Knee Joint; Lysophospholipids; Male; NAV1.8 Voltage-Gated Sodium Channel; Pain Measurement; Rats; Rats, Wistar; Sex Characteristics; Stilbamidines

Topics: Animals; Biomarkers; Disease Models, Animal; Disease Susceptibility; Fluorescent Antibody Technique; GTP-Binding Protein alpha Subunits, G12-G13; Hypertension; Lysophospholipids; Mice; rho-Associated Kinases; Signal Transduction

Topics: Animals; Cell Differentiation; Chronic Disease; Colitis; Dextran Sulfate; Disease Models, Animal; Enzyme Inhibitors; Inflammation; Lysophospholipids; Mice; Phosphoric Diester Hydrolases; Th17 Cells

Topics: Amygdala; Animals; Conditioning, Classical; Corticosterone; Cues; Disease Models, Animal; Emotions; Extinction, Psychological; Fear; Gene Expression Regulation; Isoxazoles; Lysophospholipids; Male; Mice; Mice, Knockout; Neurons; Phosphopyruvate Hydratase; Propionates; Receptors, Lysophosphatidic Acid; Stress, Psychological; Time Factors

Topics: Animals; Antibodies, Neutralizing; Disease Models, Animal; Gene Expression Regulation; Group IV Phospholipases A2; Interleukin-1beta; Lysophospholipids; Male; Mice; Mice, Inbred C57BL; Neuralgia; Phospholipases A2, Calcium-Independent; Posterior Horn Cells; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization

Topics: Allergens; Animals; Asthma; Bronchoalveolar Lavage Fluid; Disease Models, Animal; Humans; Inflammation; Lysophospholipids; Male; Mice; Mice, Transgenic; Phosphoric Diester Hydrolases; Signal Transduction

Topics: Animals; Atherosclerosis; Cell Movement; Cells, Cultured; Diabetes Mellitus; Diet, High-Fat; Disease Models, Animal; Disease Progression; Enzyme Inhibitors; Group VI Phospholipases A2; Hydrogen Peroxide; Lysophospholipids; Macrophages, Peritoneal; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; NADPH Oxidase 4; NADPH Oxidases; Oligonucleotides, Antisense; Receptors, LDL; Signal Transduction; Stress, Physiological; Time Factors; Transfection; Up-Regulation

Topics: Adult; Aged, 80 and over; Animals; Brain Injuries; Cytokines; Disease Models, Animal; Female; Glasgow Coma Scale; Humans; Immunoglobulin G; Immunologic Factors; Lysophospholipids; Male; Mice; Mice, Inbred C57BL; Middle Aged; Single-Blind Method; Young Adult

Topics: Animals; Cell Culture Techniques; Cell Proliferation; Collagen Type I; Connective Tissue Growth Factor; Disease Models, Animal; DNA-Binding Proteins; Female; Humans; Lysophospholipids; Male; Mice; Mice, Inbred C57BL; Middle Aged; Myofibroblasts; NIH 3T3 Cells; Nipecotic Acids; Oncogene Proteins, Fusion; Scleroderma, Systemic; Serum Response Factor; Trans-Activators; Transcription, Genetic; Transforming Growth Factor beta

Topics: Animals; Bone and Bones; Bone Remodeling; Bone Resorption; Calcification, Physiologic; Cell Differentiation; Disease Models, Animal; Female; Femur; Humans; Immunoenzyme Techniques; Isoxazoles; Lysophospholipids; Mice; Mice, Inbred C57BL; Osteoblasts; Osteoclasts; Osteoporosis; Osteoporosis, Postmenopausal; Ovariectomy; Propionates; Receptors, Lysophosphatidic Acid; Signal Transduction; X-Ray Microtomography

Topics: Analysis of Variance; Animals; Anxiety; Disease Models, Animal; Dose-Response Relationship, Drug; Exploratory Behavior; Lysophospholipids; Male; Maze Learning; Mice; Mice, Inbred C57BL; Motor Activity; Reaction Time; Receptors, Lysophosphatidic Acid; Time Factors

Topics: Animals; Antineoplastic Agents, Phytogenic; Disease Models, Animal; Dizocilpine Maleate; Lysophospholipids; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Neuralgia; Paclitaxel; Pain Measurement; Phospholipases A2; Piperidines; Receptors, Lysophosphatidic Acid; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Spinal Cord Dorsal Horn; Time Factors

Topics: Animals; Behavior, Animal; Brain; Disease Models, Animal; Female; Intracranial Hemorrhages; Lysophospholipids; Male; Mice; Mice, Inbred C57BL; Pregnancy; Prenatal Exposure Delayed Effects; Risk Factors; Schizophrenia; Signal Transduction

Topics: Animals; Cells, Cultured; Disease Models, Animal; Female; Fluorescent Antibody Technique, Indirect; Humans; Image Processing, Computer-Assisted; Inflammation; Luciferases; Luminescent Measurements; Lysophospholipids; Male; Mice; Mice, Transgenic; Promoter Regions, Genetic; Real-Time Polymerase Chain Reaction; Receptors, Lysophosphatidic Acid; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Up-Regulation; Uterus

Topics: Animals; Animals, Newborn; Cell Death; Cells, Cultured; Cerebral Cortex; Demyelinating Diseases; Disease Models, Animal; Evoked Potentials, Motor; Female; Lysophospholipids; Mice; Mice, Inbred C57BL; Mice, Transgenic; Microglia; Motor Activity; Oligodendroglia; Receptors, Lysophosphatidic Acid; Spinal Cord; Spinal Cord Injuries; Time Factors

Topics: Alcohol Oxidoreductases; Animals; Brain; Cerebellum; Cerebral Cortex; Corpus Striatum; Disease Models, Animal; DNA-Binding Proteins; Gene Knock-In Techniques; Glycerophospholipids; Huntingtin Protein; Huntington Disease; Lysophospholipids; Male; Mass Spectrometry; Mice; Mice, Inbred C57BL; Nerve Tissue Proteins; Neurons; Phosphatidic Acids; Synaptic Vesicles; Synaptosomes

Topics: Animals; Antigens, CD34; Apoptosis; bcl-2-Associated X Protein; Caspase 9; Cell Differentiation; Cell Hypoxia; Cell Proliferation; Cell Survival; Cells, Cultured; Cord Blood Stem Cell Transplantation; Cytokines; Disease Models, Animal; Fetal Blood; Hematopoietic Stem Cells; Humans; Ischemia; Lysophospholipids; Male; Myocardial Infarction; PPAR gamma; Rats; Signal Transduction; Treatment Outcome

Topics: Animals; Cell Line, Tumor; Cell Movement; Cell Proliferation; Disease Models, Animal; Disease Progression; Extracellular Matrix; Heterografts; Humans; Lysophospholipids; Male; Neoplasm Invasiveness; NF-kappa B; Prostatic Neoplasms; Proto-Oncogene Proteins c-akt; rhoA GTP-Binding Protein; Signal Transduction

Topics: Animals; Benzoates; Bleomycin; Case-Control Studies; Disease Models, Animal; Enzyme-Linked Immunosorbent Assay; Female; Fibroblasts; Fibrosis; Humans; Immunohistochemistry; Interleukin-6; Lysophospholipids; Mice; Phosphodiesterase Inhibitors; Phosphoric Diester Hydrolases; Real-Time Polymerase Chain Reaction; RNA, Small Interfering; Scleroderma, Systemic; Skin

Topics: Animals; Disease Models, Animal; Female; Fibrosis; Lysophospholipids; Macrophages; Muscular Atrophy; Rats, Sprague-Dawley; rhoA GTP-Binding Protein; Rotator Cuff; Rotator Cuff Injuries

Topics: Animals; Animals, Genetically Modified; Apolipoproteins B; Cell Proliferation; Cells, Cultured; Disease Models, Animal; Endothelial Cells; Gene Expression Profiling; Genotype; Green Fluorescent Proteins; Human Umbilical Vein Endothelial Cells; Humans; Hyperlipidemias; Lysophospholipids; Mutation; Neovascularization, Physiologic; Oligonucleotide Array Sequence Analysis; Phenotype; Phosphoric Diester Hydrolases; Receptors, Lysophosphatidic Acid; Signal Transduction; Transcription Factors; Zebrafish; Zebrafish Proteins

Topics: Animals; Biophysics; Bone Neoplasms; Cancer Pain; Carcinoma; Disease Models, Animal; Electric Stimulation; Enzyme Inhibitors; Female; Ganglia, Spinal; Gene Expression Regulation, Neoplastic; Hyperalgesia; Isoxazoles; Lysophospholipids; Membrane Potentials; NAV1.8 Voltage-Gated Sodium Channel; Neurons; Pain Measurement; Patch-Clamp Techniques; Propionates; Rats; Rats, Sprague-Dawley; Receptors, Lysophosphatidic Acid

Topics: Albuminuria; Animals; Disease Models, Animal; Down-Regulation; Female; Fibrosis; Gene Expression; Kidney; Lysophospholipids; Mice; Nephrectomy; Nephritis, Interstitial; Nerve Tissue Proteins; Phosphatidate Phosphatase; Phosphorylation; Renal Insufficiency, Chronic

Topics: Adaptor Proteins, Signal Transducing; Animals; Cell Line, Tumor; Cell Movement; Cell Proliferation; Disease Models, Animal; Female; Gene Expression Regulation, Neoplastic; Gene Knockdown Techniques; Heterografts; Humans; Lysophospholipids; Mice; Models, Biological; Ovarian Neoplasms; Protein Binding; Proto-Oncogene Proteins c-jun; Tumor Burden

Topics: Animals; Atherosclerosis; Cholesterol, LDL; Disease Models, Animal; Endocytosis; Humans; Isoxazoles; Lysophospholipids; Mice; Propionates; Receptors, LDL; Receptors, Lysophosphatidic Acid; Signal Transduction

Topics: Animals; Azoxymethane; Carcinogenesis; Carcinogens; Cell Transformation, Neoplastic; Colon; Colonic Neoplasms; Complex Mixtures; Dextran Sulfate; Diet, High-Fat; Disease Models, Animal; Dose-Response Relationship, Drug; Food-Drug Interactions; Glycine max; Intestinal Mucosa; Lysophospholipids; Rats; Statistics as Topic

Topics: Animals; Cell Line; Diabetes Mellitus; Diabetic Nephropathies; Disease Models, Animal; Disease Progression; Glycogen Synthase Kinase 3 beta; Isoxazoles; Kidney Cortex; Lysophospholipids; Male; Mice, Inbred C57BL; Phosphoric Diester Hydrolases; Phosphorylation; Propionates; Receptors, Lysophosphatidic Acid; RNA Interference; Signal Transduction; Smad2 Protein; Smad3 Protein; Sterol Regulatory Element Binding Protein 1; Time Factors; Transfection; Transforming Growth Factor beta

Topics: Animals; Breast Neoplasms; Cell Line, Tumor; Cytokines; Disease Models, Animal; Doxycycline; Female; Humans; Inflammation; Inflammation Mediators; Lysophospholipids; Macrophages; Mice; Neovascularization, Pathologic; NF-kappa B; Phosphorylation; Protein Transport; Tumor Burden; Xenograft Model Antitumor Assays

Topics: Animals; Breast Neoplasms; Carcinogenesis; CD36 Antigens; Cell Proliferation; Cells, Cultured; Diet; Disease Models, Animal; Endothelium, Vascular; Female; Humans; Lysophospholipids; Mice; Mice, Inbred C57BL; Obesity; Protein Kinase C; Receptors, Estrogen; Risk; Signal Transduction; Vascular Remodeling

Topics: Animals; Colon; Diarrhea; Disease Models, Animal; Intestinal Absorption; Lysophospholipids; Mice; Mice, Inbred C57BL; Mice, Knockout; Microvilli; Phosphoproteins; Receptors, Lysophosphatidic Acid; Signal Transduction; Sodium-Hydrogen Exchanger 3; Sodium-Hydrogen Exchangers; Water

Topics: Animals; Antigens, Protozoan; Asthma; Bronchoalveolar Lavage Fluid; Cyclooxygenase 2; Cytokines; Dinoprostone; Disease Models, Animal; Egg Proteins; Goblet Cells; Inflammation Mediators; Lung; Lysophospholipids; Mice; Mice, Knockout; Receptors, Lysophosphatidic Acid; Schistosoma mansoni; Signal Transduction; Th2 Cells; Time Factors

Topics: Animals; Calpain; Cysteine Proteinase Inhibitors; Demyelinating Diseases; Disease Models, Animal; Enzyme Activation; Leucine; Lysophospholipids; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Myelin-Associated Glycoprotein; Neurotoxins; Peripheral Nervous System Diseases; Receptors, Lysophosphatidic Acid; Sciatic Neuropathy; Sensory Receptor Cells; Spinal Nerve Roots

Topics: Adult; Aged; Animals; Calcium; Cell Line, Tumor; Cholestasis, Intrahepatic; Chromatography, High Pressure Liquid; Disease Models, Animal; Drainage; Female; Fluorometry; Humans; Injections, Intradermal; Liver Cirrhosis, Biliary; Lysophospholipids; Male; Mass Spectrometry; Mice; Mice, Inbred C57BL; Middle Aged; Multienzyme Complexes; Neurons; Phosphodiesterase I; Phosphoric Diester Hydrolases; Pregnancy; Pregnancy Complications; Pruritus; Pyrophosphatases; Severity of Illness Index; Time Factors; Up-Regulation

Topics: Animals; Blotting, Western; Bone Neoplasms; Disease Models, Animal; Female; Ganglia, Spinal; Gene Expression Regulation; Hyperalgesia; Lysophospholipids; Neoplasm Transplantation; Nerve Fibers, Unmyelinated; Neurons; Pain; Rats; Rats, Sprague-Dawley; Receptors, Lysophosphatidic Acid; Signal Transduction; Sural Nerve

Topics: Animals; Apolipoprotein A-I; Cell Line, Tumor; Cell Proliferation; Cell Survival; Disease Models, Animal; Drinking Behavior; Female; Humans; Injections; Lysophospholipids; Mice; Mice, Inbred C57BL; Mice, Transgenic; Neoplasm Transplantation; Ovarian Neoplasms; Peptides; Precancerous Conditions; Survival Analysis; Tumor Burden; Water

Topics: Adenocarcinoma; Adenomatous Polyposis Coli; Animals; Cell Movement; Colonic Neoplasms; Disease Models, Animal; Genes, APC; GTP-Binding Protein alpha Subunits, G12-G13; GTP-Binding Protein alpha Subunits, Gq-G11; HCT116 Cells; Humans; Inositol Phosphates; JNK Mitogen-Activated Protein Kinases; Lysophospholipids; Membrane Proteins; Mice; Neoplasm Invasiveness; NF-kappa B; Phospholipase C beta; Phosphoproteins; Receptors, Lysophosphatidic Acid; RNA Interference; Signal Transduction; Sodium-Hydrogen Exchangers; Time Factors; Tissue Array Analysis; Transfection

Topics: Adipocytes; Adipose Tissue, Brown; Adipose Tissue, White; Adiposity; Animals; Blood Glucose; Cell Size; Dietary Fats; Disease Models, Animal; Female; Founder Effect; Gene Deletion; Glucose Tolerance Test; Insulin; Lysophospholipids; Male; Mice; Mice, Knockout; Multienzyme Complexes; Obesity; Phosphodiesterase I; Phosphoric Diester Hydrolases; PPAR gamma; Pyrophosphatases

Topics: Administration, Cutaneous; Administration, Oral; Amino Acid Sequence; Animals; Apolipoprotein A-I; Apolipoproteins E; Atherosclerosis; Diet; Disease Models, Animal; Dose-Response Relationship, Drug; Feces; Female; Gene Deletion; Inflammation; Intestinal Mucosa; Lipoproteins, HDL; Liver; Lysophospholipids; Mice; Mice, Knockout; Molecular Mimicry; Molecular Sequence Data; Peptides; Serum Amyloid A Protein

Topics: Animals; Calcium Signaling; Case-Control Studies; Cell Line, Tumor; Cholestasis; Cholestasis, Intrahepatic; Disease Models, Animal; Female; Humans; Lysophospholipids; Mice; Multienzyme Complexes; Phosphodiesterase I; Phosphoric Diester Hydrolases; Pregnancy; Pregnancy Complications; Pruritus; Pyrophosphatases

Topics: Animals; Brain; Cerebral Hemorrhage; Cerebrospinal Fluid; Disease Models, Animal; Female; Fetal Diseases; Fetus; Humans; Hydrocephalus; Infant, Newborn; Lysophospholipids; Mice; Neural Stem Cells; Plasma; Pregnancy; rac GTP-Binding Proteins; Receptors, Lysophosphatidic Acid; rho GTP-Binding Proteins; Serum; Signal Transduction

Topics: Animals; Anoikis; Apoptosis; Bleomycin; Caspase 3; Cell Adhesion; Cells, Cultured; Disease Models, Animal; Epithelial Cells; Fibroblasts; Humans; Lung; Lung Injury; Lysophospholipids; Mice; Mice, 129 Strain; Mice, Inbred C57BL; Mice, Knockout; Pulmonary Fibrosis; Rats; Receptors, Lysophosphatidic Acid; Signal Transduction; Time Factors

Topics: Angioplasty; Animals; Apolipoproteins E; Blood Vessel Prosthesis Implantation; Carotid Arteries; Cell Movement; Coronary Restenosis; Disease Models, Animal; Drug-Eluting Stents; Endothelium, Vascular; Humans; Lysophospholipids; Macrophages; Mice; Mice, Knockout; Myocytes, Smooth Muscle; Neointima; Postoperative Complications; Proteins; Receptors, CXCR4; Sirolimus

Topics: Amines; Analgesics; Animals; Calcium Channels; Cyclohexanecarboxylic Acids; Disease Models, Animal; Gabapentin; gamma-Aminobutyric Acid; Ganglia, Spinal; Hyperalgesia; Indomethacin; Lysophospholipids; Male; Mice; Morphine; Motor Activity; Neuralgia; Neurons; Pregabalin; Spinal Cord

Topics: Administration, Inhalation; Adoptive Transfer; Allergens; Animals; Asthma; Dendritic Cells; Disease Models, Animal; Female; Gene Deletion; HEK293 Cells; Humans; Inflammation; Lung; Lysophospholipids; Mice; Mice, Inbred C57BL; Mice, Knockout; NF-kappa B; Receptors, Lysophosphatidic Acid; Signal Transduction; Transcription, Genetic

Topics: Amino Acid Motifs; Animals; Apoptosis Regulatory Proteins; Bleomycin; Cell Movement; Disease Models, Animal; Enzyme Activation; Enzyme Stability; Extracellular Signal-Regulated MAP Kinases; Fibroblasts; GTP-Binding Protein alpha Subunits, G12-G13; HEK293 Cells; Humans; Intracellular Signaling Peptides and Proteins; Lung; Lysophospholipids; Mechanistic Target of Rapamycin Complex 2; Mice; Mice, Inbred C57BL; Mice, Knockout; Multiprotein Complexes; Phosphorylation; Protein Kinase C-delta; Protein Stability; Proteins; Proto-Oncogene Proteins c-akt; Pulmonary Fibrosis; RNA Interference; Signal Transduction; Time Factors; TOR Serine-Threonine Kinases; Trans-Activators; Transfection; Ubiquitin-Protein Ligases; Ubiquitination

Topics: Animals; Antibodies, Monoclonal; Apoptosis; Cell Death; Cell Proliferation; Cell Survival; CHO Cells; Cricetinae; Disease Models, Animal; Enzyme-Linked Immunosorbent Assay; Humans; Inflammation; Lysophospholipids; Mice; Microglia; Motor Activity; Neurites; Neuroprotective Agents; Receptors, Lysophosphatidic Acid; Recovery of Function; Signal Transduction; Spinal Cord Injuries; Zebrafish

Topics: Adolescent; Adult; Aged; Aged, 80 and over; Animals; Biomarkers; Diabetes Mellitus, Experimental; Diabetic Retinopathy; Disease Models, Animal; Female; Humans; Lysophospholipids; Male; Middle Aged; Phosphoric Diester Hydrolases; Phosphotransferases (Alcohol Group Acceptor); Rats; Rats, Sprague-Dawley; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factor Receptor-2; Vitreous Body; Young Adult

Topics: Adenosine Triphosphate; Amino Acid Chloromethyl Ketones; Analysis of Variance; Animals; Calcium-Binding Proteins; Carrier Proteins; Cathepsin B; CD11b Antigen; CD4 Antigens; Cells, Cultured; Chromogranin A; Chronic Pain; Cyclooxygenase 2; Dipeptides; Disease Models, Animal; Dose-Response Relationship, Drug; Enzyme Inhibitors; Freund's Adjuvant; Functional Laterality; Ganglia, Spinal; Gene Expression Regulation; Hyperalgesia; Inflammation; Interleukin-18; Interleukin-1beta; Lysophospholipids; Lysosomes; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Microfilament Proteins; Microglia; Motor Activity; Nerve Tissue Proteins; NLR Family, Pyrin Domain-Containing 3 Protein; Pain Threshold; RNA, Small Interfering; Spinal Cord; Transfection

Topics: Animals; Carotid Artery Injuries; Carotid Artery, Common; Cell Movement; Cell Proliferation; Disease Models, Animal; Enzyme Activation; Extracellular Signal-Regulated MAP Kinases; Gene Expression Regulation; Genotype; HEK293 Cells; Humans; Hydrolysis; Hyperplasia; Lysophospholipids; Mice; Mice, Inbred C57BL; Mice, Knockout; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Neointima; Phenotype; Phosphatidate Phosphatase; rho-Associated Kinases; Signal Transduction; Time Factors; Transfection

Topics: Anilides; Animals; Benzamides; Biphenyl Compounds; Cell Proliferation; Chlorhexidine; Connective Tissue Growth Factor; Cytoskeleton; Disease Models, Animal; Epithelial Cells; Epithelium; Isoxazoles; Lysophospholipids; Mice; Mice, Inbred C57BL; Mice, Knockout; Myofibroblasts; Peritoneal Fibrosis; Receptors, Lysophosphatidic Acid; Trans-Activators; Transcription Factors

Topics: Animals; Ascites; Cell Line, Tumor; Culture Media, Conditioned; Disease Models, Animal; Epithelial Cells; Epithelium; Female; Humans; Isoxazoles; Lysophospholipids; Mice; Mice, Inbred BALB C; Mice, Nude; Pertussis Toxin; Propionates; Receptors, Lysophosphatidic Acid; RNA, Messenger; Stomach Neoplasms; Vascular Endothelial Growth Factor A

Topics: Animals; Apoptosis; Brain Ischemia; Disease Models, Animal; Dose-Response Relationship, Drug; Electroretinography; Intraocular Pressure; Lysophospholipids; Male; Nerve Degeneration; Neuroprotective Agents; Rats; Rats, Sprague-Dawley; Receptors, Lysophosphatidic Acid; Receptors, Lysosphingolipid; Reperfusion Injury; Retinal Diseases; Signal Transduction; Treatment Outcome

Topics: Actins; Analysis of Variance; Animals; Apoptosis; Cell Movement; Cell Survival; Cells, Cultured; Disease Models, Animal; Female; Ganglia, Spinal; Lysophospholipids; Mice; Mice, Inbred C57BL; Mice, Knockout; Neurofibroma; Neurofibromatosis 1; Neurofibromin 1; Phosphatidylinositol 3-Kinases; Pregnancy; Pregnancy Complications; Proto-Oncogene Proteins c-akt; ras GTPase-Activating Proteins; Schwann Cells; Signal Transduction; Statistics, Nonparametric

Topics: Animals; Aorta, Abdominal; Biomarkers; Blood Vessels; Carotid Artery Injuries; Cell Proliferation; Cells, Cultured; Coronary Restenosis; Disease Models, Animal; Intracellular Signaling Peptides and Proteins; Lysophospholipids; Male; Membrane Proteins; Mice; Mice, Inbred C57BL; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Phenylephrine; Platelet-Derived Growth Factor; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-1; RNA, Small Interfering; Stents; Sterol Regulatory Element Binding Protein 1