lysophosphatidic acid has been researched along with Colonic Neoplasms in 26 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 12 (46.15) | 29.6817 |
| 2010's | 13 (50.00) | 24.3611 |
| 2020's | 1 (3.85) | 2.80 |
| Authors | Studies |
|---|---|
| Long, Y; Qu, M; Wang, Y; Zhang, D; Zhang, J; Zhang, X | 1 |
| Fukushima, K; Fukushima, N; Honoki, K; Ishimoto, K; Minami, K; Otagaki, S; Takahashi, K; Tsujiuchi, T | 1 |
| Dang, DT; Dang, LH; Lee, SJ; No, YR; Shim, H; Yang, VW; Yun, CC | 1 |
| Guo, L; He, P; No, YR; Yun, CC | 1 |
| Bhuwania, R; Failla, AV; Gromova, K; Izbicki, JR; Kneussel, M; Lange, T; Lin, YN; Linder, S; Riecken, K; Windhorst, S | 1 |
| Abdelhay, E; Binato, R; Leve, F; Morgado-Díaz, JA; Peres-Moreira, RJ | 1 |
| Fukushima, K; Fukushima, N; Honoki, K; Inui, K; Node, Y; Onishi, Y; Takahashi, K; Tsujiuchi, T | 1 |
| Inoue, M; Ishihara, A; Okamoto, Y; Tokumura, A; Tsutsumi, T | 1 |
| Alvarez, SE; Fang, X; Kordula, T; Lépine, S; Milstien, S; Shida, D; Spiegel, S; Takabe, K | 1 |
| Chen, CK; Cheng, CT; Fang, X; Lee, Z; Mukherjee, A; Subler, MA; Windle, JJ; Wu, J; Zhang, H | 1 |
| Kong, FZ; Pan, BR; Ren, J; Sun, H; Wu, L; Zhu, Q | 1 |
| Berliner, C; Bialecki, W; Kleuser, B; Leptin, J; Milićević, NM; Müller, R; Pörtner, D; Schumacher, U | 1 |
| Hall, RA; Lee, SJ; Ritter, SL; Shim, H; Yun, CC; Zhang, H | 1 |
| Bastos, LG; Leve, F; Marcondes, TG; Morgado-Díaz, JA; Rabello, SV; Tanaka, MN | 1 |
| Farias-Eisner, R; Fogelman, AM; Ganapathy, E; Grijalva, V; Imaizumi, S; Meriwether, D; Navab, K; Navab, M; Reddy, ST; Su, F | 1 |
| Fukui, R; Fukushima, N; Kitayoshi, M; Tanabe, E; Tsujiuchi, T; Yoshikawa, K | 1 |
| Murakami-Murofushi, K; Tsukahara, T | 1 |
| Baba, M; Higashino, K; Iishi, H; Ishiguro, S; Ishihara, R; Mukai, M; Tatsuta, M; Uedo, N | 1 |
| Castleberry, A; Hall, RA; Rusovici, R; Shim, H; Sun, H; Wang, D; Yun, CC | 1 |
| An, S; Hoey, T; Slavin, A; Srivastava, N; Yang, J; Yang, M; Zhong, WW | 1 |
| Malbon, CC | 1 |
| Kitayama, J; Mori, K; Nagawa, H; Shida, D; Watanabe, T; Yamaguchi, H; Yamashita, H | 1 |
| Kitayama, J; Mori, K; Nagawa, H; Shida, D; Watanabe, T; Yamashita, H | 1 |
| Balavenkatraman, KK; Böhmer, FD; Friedrich, K; Jandt, E; Kautenburger, T; Ostman, A; Pool-Zobel, BL | 1 |
| Ghaleb, A; Rusovici, R; Shim, H; Yang, VW; Yun, CC | 1 |
| Han, M; Im, DS; Jo, JY; Kim, HL; Kim, K; Kim, YL; Lee, YK; Sacket, SJ | 1 |
1 review(s) available for lysophosphatidic acid and Colonic Neoplasms
| Article | Year |
|---|---|
Beta-catenin, cancer, and G proteins: not just for frizzleds anymore.
Topics: Animals; beta Catenin; Cell Line, Tumor; Colonic Neoplasms; Frizzled Receptors; Heterotrimeric GTP-Binding Proteins; Humans; Invertebrates; Isoenzymes; JNK Mitogen-Activated Protein Kinases; Lymphoid Enhancer-Binding Factor 1; Lysophospholipids; Models, Biological; Neoplasm Proteins; Neoplasms; Phospholipase C beta; Protein Kinase C; Receptors, Lysophosphatidic Acid; Signal Transduction; Type C Phospholipases; Vertebrates; Wnt Proteins | 2005 |
25 other study(ies) available for lysophosphatidic acid and Colonic Neoplasms
| Article | Year |
|---|---|
Combined inhibition of EZH2 and the autotaxin-LPA-LPA2 axis exerts synergistic antitumor effects on colon cancer cells.
Topics: Cell Line, Tumor; Colonic Neoplasms; Enhancer of Zeste Homolog 2 Protein; Humans; Lysophospholipids; Receptors, Lysophosphatidic Acid | 2023 |
Effects of LPA
Topics: Antineoplastic Agents; Cell Line, Tumor; Cell Movement; Cisplatin; Colonic Neoplasms; Fluorouracil; Gene Expression Regulation, Neoplastic; Humans; Lysophospholipids; Receptors, Lysophosphatidic Acid; Stem Cells | 2018 |
Regulation of hypoxia-inducible factor 1α (HIF-1α) by lysophosphatidic acid is dependent on interplay between p53 and Krüppel-like factor 5.
Topics: Cell Line, Tumor; Colonic Neoplasms; Gene Silencing; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; Kruppel-Like Transcription Factors; Lysophospholipids; Mutation; Protein Binding; Response Elements; Trans-Activators; Tumor Suppressor Protein p53 | 2013 |
Krüppel-like factor 5 incorporates into the β-catenin/TCF complex in response to LPA in colon cancer cells.
Topics: Basic Helix-Loop-Helix Leucine Zipper Transcription Factors; beta Catenin; Cell Line, Tumor; Cell Nucleus; Colon; Colonic Neoplasms; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; Humans; Kruppel-Like Transcription Factors; Lysophospholipids; Phosphorylation; Transcription Factor 4; Transcription Factors | 2015 |
Drosophila homologue of Diaphanous 1 (DIAPH1) controls the metastatic potential of colon cancer cells by regulating microtubule-dependent adhesion.
Topics: Actin Cytoskeleton; Adaptor Proteins, Signal Transducing; Animals; Blotting, Western; Cell Adhesion; Colonic Neoplasms; Formins; HCT116 Cells; HEK293 Cells; Humans; Integrin beta1; Lysophospholipids; Mice, SCID; Microscopy, Fluorescence; Microtubules; Neoplasm Metastasis; RNA Interference; Time-Lapse Imaging; Transplantation, Heterologous | 2015 |
LPA Induces Colon Cancer Cell Proliferation through a Cooperation between the ROCK and STAT-3 Pathways.
Topics: Apoptosis; beta Catenin; Blotting, Western; Cell Cycle; Cell Movement; Cell Proliferation; Colonic Neoplasms; Fluorescent Antibody Technique; Humans; Lysophospholipids; Phosphorylation; Receptors, Lysophosphatidic Acid; rho-Associated Kinases; Signal Transduction; STAT3 Transcription Factor; Tumor Cells, Cultured; Wound Healing | 2015 |
Lysophosphatidic acid (LPA) signaling via LPA
Topics: Antimetabolites, Antineoplastic; Cell Line, Tumor; Cell Movement; Colonic Neoplasms; Fluorouracil; HCT116 Cells; Humans; Lysophospholipids; Receptors, Lysophosphatidic Acid; Receptors, Purinergic; Receptors, Purinergic P2; Signal Transduction | 2017 |
Daily Intake of High-Fat Diet with Lysophosphatidic Acid-Rich Soybean Phospholipids Augments Colon Tumorigenesis in Kyoto Apc Delta Rats.
Topics: Animals; Azoxymethane; Carcinogenesis; Carcinogens; Cell Transformation, Neoplastic; Colon; Colonic Neoplasms; Complex Mixtures; Dextran Sulfate; Diet, High-Fat; Disease Models, Animal; Dose-Response Relationship, Drug; Food-Drug Interactions; Glycine max; Intestinal Mucosa; Lysophospholipids; Rats; Statistics as Topic | 2017 |
Cross-talk between LPA1 and epidermal growth factor receptors mediates up-regulation of sphingosine kinase 1 to promote gastric cancer cell motility and invasion.
Topics: Blotting, Western; Breast Neoplasms; Cell Movement; Cell Proliferation; Chemotaxis; Colonic Neoplasms; ErbB Receptors; Humans; Interleukin-6; Interleukin-8; Lysophospholipids; Neoplasm Invasiveness; Phosphotransferases (Alcohol Group Acceptor); Receptors, Lysophosphatidic Acid; Receptors, Lysosphingolipid; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Sphingosine; Stomach Neoplasms; Transcriptional Activation; Tumor Cells, Cultured; Up-Regulation; Urokinase-Type Plasminogen Activator | 2008 |
Role of LPA4/p2y9/GPR23 in negative regulation of cell motility.
Topics: Animals; Cell Line, Tumor; Cell Movement; Cells, Cultured; Colonic Neoplasms; Enzyme Activation; Female; Fibroblasts; Humans; Lysophospholipids; Male; Mice; Mice, Knockout; Neoplasm Invasiveness; Protein Isoforms; Proto-Oncogene Proteins c-akt; rac GTP-Binding Proteins; Receptors, Lysophosphatidic Acid; Receptors, Purinergic; Signal Transduction; Tissue Distribution | 2008 |
Effects of lysophosphatidic acid on human colon cancer cells and its mechanisms of action.
Topics: Apoptosis; Cell Adhesion; Cell Line, Tumor; Cell Movement; Cell Proliferation; Colonic Neoplasms; Humans; Lysophospholipids | 2009 |
Expression of sphingosine-1-phosphate receptors and lysophosphatidic acid receptors on cultured and xenografted human colon, breast, melanoma, and lung tumor cells.
Topics: Animals; Breast Neoplasms; Colonic Neoplasms; Endothelium, Vascular; Female; Humans; Immunoenzyme Techniques; Lung Neoplasms; Lysophospholipids; Melanoma; Mice; Mice, SCID; Neoplasm Transplantation; Receptors, Lysophosphatidic Acid; Receptors, Lysosphingolipid; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Sphingosine; Transplantation, Heterologous; Tumor Cells, Cultured; Umbilical Cord | 2010 |
MAGI-3 competes with NHERF-2 to negatively regulate LPA2 receptor signaling in colon cancer cells.
Topics: Adenocarcinoma; Adenomatous Polyposis Coli; Animals; Cell Movement; Colonic Neoplasms; Disease Models, Animal; Genes, APC; GTP-Binding Protein alpha Subunits, G12-G13; GTP-Binding Protein alpha Subunits, Gq-G11; HCT116 Cells; Humans; Inositol Phosphates; JNK Mitogen-Activated Protein Kinases; Lysophospholipids; Membrane Proteins; Mice; Neoplasm Invasiveness; NF-kappa B; Phospholipase C beta; Phosphoproteins; Receptors, Lysophosphatidic Acid; RNA Interference; Signal Transduction; Sodium-Hydrogen Exchangers; Time Factors; Tissue Array Analysis; Transfection | 2011 |
Lysophosphatidic acid induces a migratory phenotype through a crosstalk between RhoA-Rock and Src-FAK signalling in colon cancer cells.
Topics: Adherens Junctions; Caco-2 Cells; Cell Movement; Colonic Neoplasms; Disease Progression; Focal Adhesion Kinase 1; Focal Adhesions; Humans; Lysophospholipids; Phenotype; Protein Kinases; Proto-Oncogene Proteins pp60(c-src); rho-Associated Kinases; rhoA GTP-Binding Protein; Signal Transduction; Stress Fibers | 2011 |
HDL mimetics inhibit tumor development in both induced and spontaneous mouse models of colon cancer.
Topics: Animals; Antineoplastic Agents; Apolipoprotein A-I; Clusterin; Colon; Colonic Neoplasms; Female; Lipoproteins, HDL; Lysophospholipids; Male; Mice; Molecular Mimicry; Neoplasm Transplantation; Peptides | 2012 |
Negative regulation of cell motile and invasive activities by lysophosphatidic acid receptor-3 in colon cancer HCT116 cells.
Topics: Blotting, Western; Cell Adhesion; Cell Movement; Cell Proliferation; Cells, Cultured; Colonic Neoplasms; Endothelium, Vascular; Humans; Lysophospholipids; Neoplasm Invasiveness; Real-Time Polymerase Chain Reaction; Receptors, Lysophosphatidic Acid; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; RNA, Small Interfering; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factor C | 2012 |
Release of cyclic phosphatidic acid from gelatin-based hydrogels inhibit colon cancer cell growth and migration.
Topics: Cell Movement; Cell Proliferation; Colonic Neoplasms; Drug Delivery Systems; Gelatin; HT29 Cells; Humans; Hydrogels; Lysophospholipids; Microspheres; Nanoparticles; Phosphatidic Acids; PPAR gamma | 2012 |
Induction by lysophosphatidic acid of peritoneal and pleural metastases of intestinal cancers induced by azoxymethane in Wistar rats.
Topics: Adenocarcinoma; Animals; Azoxymethane; Body Weight; Carcinogens; Colonic Neoplasms; Intestinal Neoplasms; Lysophospholipids; Male; Peritoneal Neoplasms; Pleural Neoplasms; Proliferating Cell Nuclear Antigen; Rats; Rats, Wistar; rhoA GTP-Binding Protein | 2005 |
LPA2 receptor mediates mitogenic signals in human colon cancer cells.
Topics: Caco-2 Cells; Colonic Neoplasms; Cytoskeletal Proteins; Drug Interactions; Enzyme Activation; Humans; Interleukin-8; Intestinal Mucosa; Lysophospholipids; Mitogen-Activated Protein Kinase Kinases; Mitosis; Phosphoproteins; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Receptors, Lysophosphatidic Acid; RNA, Small Interfering; Signal Transduction; Sodium-Hydrogen Exchangers | 2005 |
G protein-coupled lysophosphatidic acid receptors stimulate proliferation of colon cancer cells through the {beta}-catenin pathway.
Topics: Base Sequence; beta Catenin; Cell Division; Cell Line, Tumor; Colonic Neoplasms; Cytoskeletal Proteins; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; GTP-Binding Proteins; Humans; Lysophospholipids; Receptors, Lysophosphatidic Acid; RNA, Small Interfering; Signal Transduction; Trans-Activators; Transfection | 2005 |
Lysophosphatidic acid transactivates both c-Met and epidermal growth factor receptor, and induces cyclooxygenase-2 expression in human colon cancer LoVo cells.
Topics: Cell Line, Tumor; Colonic Neoplasms; Cyclooxygenase 2; Cyclooxygenase Inhibitors; Enzyme Induction; ErbB Receptors; Gene Expression Regulation, Neoplastic; Humans; Lysophospholipids; Nitrobenzenes; Phosphorylation; Proto-Oncogene Proteins c-met; Signal Transduction; Sulfonamides; Transcriptional Activation; Up-Regulation | 2005 |
Lysophosphatidic acid-induced effects in human colon carcinoma DLD1 cells are partially dependent on transactivation of epidermal growth factor receptor.
Topics: Cell Line, Tumor; Chemotaxis; Colonic Neoplasms; Dipeptides; Enzyme Inhibitors; Enzyme-Linked Immunosorbent Assay; ErbB Receptors; Humans; Interleukin-8; Lysophospholipids; Phosphorylation; Phosphotyrosine; Protease Inhibitors; Quinazolines; Transcriptional Activation; Tyrphostins | 2006 |
DEP-1 protein tyrosine phosphatase inhibits proliferation and migration of colon carcinoma cells and is upregulated by protective nutrients.
Topics: Adenocarcinoma; Adenoma; Anticarcinogenic Agents; Butyrates; Cell Division; Cell Line, Tumor; Cell Movement; Cells, Cultured; Chemokine CXCL12; Chemokines, CXC; Colon; Colonic Neoplasms; Down-Regulation; Enzyme Induction; Epithelial Cells; Flavonoids; Humans; Lysophospholipids; Malus; Neoplasm Proteins; Phenols; Plant Extracts; Polyphenols; Protein Phosphatase 1; Protein Tyrosine Phosphatases; Receptor-Like Protein Tyrosine Phosphatases, Class 3; Recombinant Fusion Proteins; RNA Interference; RNA, Messenger; RNA, Neoplasm; RNA, Small Interfering; Tea; Transcription, Genetic; Transfection; Up-Regulation | 2006 |
Lysophosphatidic acid prevents apoptosis of Caco-2 colon cancer cells via activation of mitogen-activated protein kinase and phosphorylation of Bad.
Topics: Annexin A5; Apoptosis; bcl-Associated Death Protein; Caco-2 Cells; Caspase 3; Caspase 7; Colonic Neoplasms; Enzyme Activation; Humans; Immunohistochemistry; Lysophospholipids; Mitogen-Activated Protein Kinases; Phosphorylation | 2007 |
Lysophosphatidylserine induces calcium signaling through Ki16425/VPC32183-sensitive GPCR in bone marrow-derived mast cells and in C6 glioma and colon cancer cells.
Topics: Animals; Bone Marrow Cells; Calcium Signaling; Colonic Neoplasms; Dose-Response Relationship, Drug; Enzyme Inhibitors; Estrenes; Glioma; HCT116 Cells; Humans; Inositol 1,4,5-Trisphosphate Receptors; Isoxazoles; Lysophospholipids; Male; Mast Cells; Mice; Mice, Inbred BALB C; Organophosphates; Pertussis Toxin; Propionates; Pyridines; Pyrrolidinones; Rats; Receptors, Lysophosphatidic Acid; Time Factors; Type C Phospholipases | 2008 |