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lysophosphatidic acid and Cell Transformation, Neoplastic

lysophosphatidic acid has been researched along with Cell Transformation, Neoplastic in 17 studies

Research

Studies (17)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's5 (29.41)29.6817
2010's9 (52.94)24.3611
2020's3 (17.65)2.80

Authors

AuthorsStudies
Chan, AWH; Coker, OO; Lau, HCH; Li, C; Lin, Y; Sung, JJY; Szeto, CH; Wei, H; Yang, J; Yu, J; Zhou, Y1
Androsov, G; Feng, Y; Gurung, AC; Herbert, ZT; Kavanagh, TR; Mischler, WJ; Priolo, C; Sadow, PM1
Bai, H; Cao, G; Cui, R; Zhang, Z1
Ben-Mrad, M; El Meddeb Hamrouni, A; Espenel, S; Guy, JB; Langrand-Escure, J; Magné, N; Rancoule, C; Rehailia-Blanchard, A; Trone, JC; Vallard, A; Xia, Y1
Balazs, L; Balogh, A; Lee, SC; Norman, DD; Szabo, E; Tigyi, GJ; Yue, J; Zhao, G1
Benned-Jensen, T; Fares, S; Gasbjerg, LS; Hjortø, GM; Mølleskov-Jensen, AS; Niss Arfelt, K; Rosenkilde, MM; Sparre-Ulrich, AH1
Inoue, M; Ishihara, A; Okamoto, Y; Tokumura, A; Tsutsumi, T1
Jacobs, JJ; Lambooij, JP; Moolenaar, WH; Stortelers, C; Taghavi, P; Tanger, E; van Lohuizen, M; Verhoeven, E1
Barbolina, MV; Burkhalter, RJ; Forgacs, G; Hudson, LG; Liu, Y; Marga, F; Moss, NM; Stack, MS; Westfall, SD1
Fishman, DA; Pua, TL; Wang, FQ1
Lee, HY; Mills, GB; Panupinthu, N1
Shimizu, Y; Tokumura, A1
Bonamy, GM; DeRan, M; Liu, J; Miller, E; Peters, EC; Su, AI; Wu, C; Wu, X; Yang, J1
Fells, JI; Fujiwara, Y; Kiss, GN; Lee, SC; Liu, J; Sümegi, B; Thompson, KE; Tigyi, G; Valentine, WJ; Yates, CR1
Maluccio, M; Skill, N; Wu, J; Xu, Y; Zhao, Z1
Barnes, J; Boudreau, N; Cayer, M; Hall, C; Heckman, CA; Kozma, R; Li, Y; Lim, L; Plummer, HK; Urban, JM1
Dhanasekaran, N; Hee Ha, J; Jayaraman, M; Radhika, V; Tsim, ST1

Reviews

7 review(s) available for lysophosphatidic acid and Cell Transformation, Neoplastic

ArticleYear
The Role of Lysophosphatidic Acid Receptors in Ovarian Cancer: A Minireview.
    Critical reviews in eukaryotic gene expression, 2020, Volume: 30, Issue:3

    Topics: AMP-Activated Protein Kinases; Cell Transformation, Neoplastic; Chemokine CXCL1; Cyclin D1; Cyclooxygenase 2; Cytoskeletal Proteins; Disease Progression; Female; Gene Expression Regulation, Neoplastic; Humans; Interleukins; Lysophospholipids; Ovarian Neoplasms; Peptide Fragments; Receptors, Lysophosphatidic Acid; Signal Transduction; Urokinase-Type Plasminogen Activator; Vascular Endothelial Growth Factor A

2020
Lysophosphatidic acid (LPA) as a pro-fibrotic and pro-oncogenic factor: a pivotal target to improve the radiotherapy therapeutic index.
    Oncotarget, 2017, Jun-27, Volume: 8, Issue:26

    Topics: Animals; Biomarkers; Cell Transformation, Neoplastic; Fibrosis; Humans; Lysophospholipids; Neoplasms; Radiation Tolerance; Radiation, Ionizing; Radiotherapy; Signal Transduction; Therapeutic Index

2017
Regulation of tumor cell - Microenvironment interaction by the autotaxin-lysophosphatidic acid receptor axis.
    Advances in biological regulation, 2019, Volume: 71

    Topics: Animals; Cell Movement; Cell Proliferation; Cell Transformation, Neoplastic; Humans; Lysophospholipids; Neoplasm Proteins; Neoplasms; Phosphoric Diester Hydrolases; Receptors, Lysophosphatidic Acid; Signal Transduction; Tumor Microenvironment

2019
Microenvironmental regulation of ovarian cancer metastasis.
    Cancer treatment and research, 2009, Volume: 149

    Topics: Ascites; Cadherins; Carcinoma; Cell Adhesion; Cell Dedifferentiation; Cell Differentiation; Cell Transformation, Neoplastic; Cytokines; Epithelial Cells; Extracellular Matrix; Female; Fibroblasts; Humans; Inflammation; Integrins; Intercellular Signaling Peptides and Proteins; Lysophospholipids; Neoplasm Proteins; Ovarian Neoplasms; Peptide Hydrolases; Peritoneal Neoplasms; Phenotype

2009
Roles of LPA in ovarian cancer development and progression.
    Future oncology (London, England), 2009, Volume: 5, Issue:10

    Topics: Animals; Cell Transformation, Neoplastic; Disease Progression; Female; Humans; Lysophospholipids; Ovarian Neoplasms; Signal Transduction

2009
Lysophosphatidic acid production and action: critical new players in breast cancer initiation and progression.
    British journal of cancer, 2010, Mar-16, Volume: 102, Issue:6

    Topics: Animals; Breast Neoplasms; Cell Transformation, Neoplastic; Disease Progression; Female; Humans; Lysophospholipids; Mice; Models, Biological; Multienzyme Complexes; Phosphodiesterase I; Phosphoric Diester Hydrolases; Pyrophosphatases; Receptors, Lysophosphatidic Acid; Signal Transduction

2010
[Physiological role of lysophosphatidic acid and its relevancephysiological role of lysophosphatidic acid and its relevance to diseases].
    Seikagaku. The Journal of Japanese Biochemical Society, 2011, Volume: 83, Issue:6

    Topics: Animals; Arteriosclerosis; Cell Transformation, Neoplastic; Fibrosis; Humans; Lysophospholipids; Receptors, Lysophosphatidic Acid

2011

Other Studies

10 other study(ies) available for lysophosphatidic acid and Cell Transformation, Neoplastic

ArticleYear
High-Fat Diet Promotes Colorectal Tumorigenesis Through Modulating Gut Microbiota and Metabolites.
    Gastroenterology, 2022, Volume: 162, Issue:1

    Topics: Animals; Anti-Bacterial Agents; Azoxymethane; Bacteria; Bacterial Translocation; Cell Proliferation; Cell Transformation, Neoplastic; Colon; Colorectal Neoplasms; Diet, High-Fat; Disease Models, Animal; Dysbiosis; Fecal Microbiota Transplantation; Feces; Gastrointestinal Microbiome; Genes, APC; Germ-Free Life; Humans; Lysophospholipids; Male; Mice, Inbred BALB C; Mice, Inbred C57BL; Mice, Transgenic; Permeability; Tumor Cells, Cultured

2022
Therapeutic Targeting of the Secreted Lysophospholipase D Autotaxin Suppresses Tuberous Sclerosis Complex-Associated Tumorigenesis.
    Cancer research, 2020, 07-01, Volume: 80, Issue:13

    Topics: Angiomyolipoma; Animals; Apoptosis; Ataxin-1; Cell Movement; Cell Proliferation; Cell Transformation, Neoplastic; Female; Humans; Imidazoles; Kidney Neoplasms; Lysophospholipids; Mice; Mice, Inbred NOD; Mice, Knockout; Pyrimidines; Signal Transduction; Sphingosine; Tuberous Sclerosis; Tuberous Sclerosis Complex 2 Protein; Tumor Cells, Cultured

2020
Signaling via G proteins mediates tumorigenic effects of GPR87.
    Cellular signalling, 2017, Volume: 30

    Topics: Animals; Carcinogenesis; Cell Membrane; Cell Transformation, Neoplastic; Chlorocebus aethiops; COS Cells; Cyclic AMP; Female; GTP-Binding Proteins; HEK293 Cells; Humans; Inositol 1,4,5-Trisphosphate; Ligands; Lysophospholipids; Mice; Mice, Inbred BALB C; Mice, Nude; Models, Biological; Mutant Proteins; NIH 3T3 Cells; Receptors, Lysophosphatidic Acid; rho GTP-Binding Proteins; rho-Associated Kinases; Signal Transduction; Transcription Factors; Transfection

2017
Daily Intake of High-Fat Diet with Lysophosphatidic Acid-Rich Soybean Phospholipids Augments Colon Tumorigenesis in Kyoto Apc Delta Rats.
    Digestive diseases and sciences, 2017, Volume: 62, Issue:3

    Topics: Animals; Azoxymethane; Carcinogenesis; Carcinogens; Cell Transformation, Neoplastic; Colon; Colonic Neoplasms; Complex Mixtures; Dextran Sulfate; Diet, High-Fat; Disease Models, Animal; Dose-Response Relationship, Drug; Food-Drug Interactions; Glycine max; Intestinal Mucosa; Lysophospholipids; Rats; Statistics as Topic

2017
In vitro genetic screen identifies a cooperative role for LPA signaling and c-Myc in cell transformation.
    Oncogene, 2008, Nov-20, Volume: 27, Issue:54

    Topics: Animals; Cell Division; Cell Survival; Cell Transformation, Neoplastic; Cyclin-Dependent Kinase Inhibitor p16; Embryo, Mammalian; Extracellular Signal-Regulated MAP Kinases; Fibroblasts; Gene Expression Regulation, Neoplastic; Genes, myc; Genetic Testing; Humans; Lysophospholipids; Mice; Neoplasms; Receptors, Lysophosphatidic Acid

2008
Identification of serum-derived sphingosine-1-phosphate as a small molecule regulator of YAP.
    Chemistry & biology, 2012, Aug-24, Volume: 19, Issue:8

    Topics: Actins; Animals; Cell Cycle Proteins; Cell Nucleus; Cell Proliferation; Cell Transformation, Neoplastic; Embryonic Stem Cells; Gene Expression Regulation; HEK293 Cells; Humans; Lysophospholipids; Mice; Nuclear Proteins; Phosphorylation; Receptors, Lysosphingolipid; rho GTP-Binding Proteins; Signal Transduction; Sphingosine; Transcription Factors

2012
Mitigation of radiation injury by selective stimulation of the LPA(2) receptor.
    Biochimica et biophysica acta, 2013, Volume: 1831, Issue:1

    Topics: Acute Radiation Syndrome; Animals; Apoptosis; Bystander Effect; Caspase Inhibitors; Caspases; Cell Transformation, Neoplastic; Cytoprotection; DNA Fragmentation; Embryo, Mammalian; Enzyme Activation; Extracellular Signal-Regulated MAP Kinases; Fibroblasts; Gamma Rays; Lysophospholipids; Mice; Mice, Knockout; Organophosphorus Compounds; Phosphoric Diester Hydrolases; Radiation Injuries; Receptors, Lysophosphatidic Acid; RNA, Messenger; Survival Analysis

2013
Lysophosphatidic acid aberrancies and hepatocellular carcinoma: studies in the MDR2 gene knockout mouse.
    Cancer investigation, 2013, Volume: 31, Issue:2

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP-Binding Cassette Sub-Family B Member 4; Cell Transformation, Neoplastic; Drug Resistance, Multiple; Liver Neoplasms; Liver Neoplasms, Experimental; Lysophospholipids; Mice; Mice, Knockout; Phosphodiesterase Inhibitors; Phospholipids; Phosphoric Diester Hydrolases; Receptors, Lysosphingolipid; Signal Transduction

2013
Novel p21-activated kinase-dependent protrusions characteristically formed at the edge of transformed cells.
    Experimental cell research, 2004, May-01, Volume: 295, Issue:2

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Actins; Animals; Calcium-Binding Proteins; Carcinogens; cdc42 GTP-Binding Protein; Cell Cycle Proteins; Cell Line, Transformed; Cell Line, Tumor; Cell Size; Cell Surface Extensions; Cell Transformation, Neoplastic; Enzyme Activation; Epithelial Cells; Guanine Nucleotide Exchange Factors; Lysophospholipids; Microscopy, Electron, Scanning; Models, Biological; p21-Activated Kinases; Protein Serine-Threonine Kinases; Rats; Rats, Inbred F344; Rho Guanine Nucleotide Exchange Factors; Tetradecanoylphorbol Acetate; Time Factors; Trachea

2004
Mitogenic signaling by lysophosphatidic acid (LPA) involves Galpha12.
    Oncogene, 2005, Jun-30, Volume: 24, Issue:28

    Topics: 3T3 Cells; Animals; Cell Proliferation; Cell Transformation, Neoplastic; Enzyme Activation; GTP-Binding Protein alpha Subunits, G12-G13; Guanosine Diphosphate; Guanosine Triphosphate; JNK Mitogen-Activated Protein Kinases; Lysophospholipids; Mice; Pertussis Toxin; Receptors, Lysophosphatidic Acid; Signal Transduction; Suramin

2005