lysophosphatidic acid and Breast Neoplasms

Topics: Animals; Breast Neoplasms; Cell Movement; Cell Proliferation; Female; Humans; Lysophospholipids; Neoplasm Invasiveness; Neoplasm Proteins; Phosphoric Diester Hydrolases; Signal Transduction

Topics: Animals; Breast Neoplasms; Female; Inflammation; Lysophospholipids; Mice; Mice, Transgenic; Models, Biological; Multienzyme Complexes; Phosphodiesterase I; Phosphoric Diester Hydrolases; Pyrophosphatases; Receptors, Lysophosphatidic Acid; Signal Transduction

Topics: Animals; Breast Neoplasms; Cell Transformation, Neoplastic; Disease Progression; Female; Humans; Lysophospholipids; Mice; Models, Biological; Multienzyme Complexes; Phosphodiesterase I; Phosphoric Diester Hydrolases; Pyrophosphatases; Receptors, Lysophosphatidic Acid; Signal Transduction

Topics: Breast Neoplasms; Cardiovascular Physiological Phenomena; Female; Gastrointestinal Tract; Genitalia; Humans; Lysophospholipids; Male; Nervous System Physiological Phenomena; Prostatic Neoplasms

Topics: Blood Platelets; Bone and Bones; Breast Neoplasms; Cell Line, Tumor; Disease Progression; Female; Humans; Lysophospholipids; Models, Biological; Neoplasm Metastasis; Neovascularization, Pathologic; Osteolysis; Ovarian Neoplasms

Topics: Breast Neoplasms; Computer-Aided Design; Drug Evaluation, Preclinical; Enzyme Assays; Enzyme Inhibitors; Female; Humans; Lysophosphatidylcholines; Lysophospholipids; Multienzyme Complexes; Phosphodiesterase I; Phosphoric Diester Hydrolases; Pipemidic Acid; Pyrophosphatases; Quantitative Structure-Activity Relationship; Tumor Cells, Cultured

Topics: Breast Neoplasms; Cytomegalovirus; Cytomegalovirus Infections; Female; Fibroblasts; Gene Expression Regulation, Neoplastic; Humans; Lysophospholipids; MCF-7 Cells; Neoplasm Metastasis; Receptor, Platelet-Derived Growth Factor alpha; Signal Transduction; Tumor Microenvironment; Virus Internalization

Topics: Animals; Breast Neoplasms; Carcinogenesis; Cell Line, Tumor; Cell Movement; Cell Proliferation; Epithelial-Mesenchymal Transition; Female; Gene Knockdown Techniques; Humans; Lung Neoplasms; Lymphocytes, Tumor-Infiltrating; Lysophospholipids; Mice, Inbred BALB C; Mice, Nude; Neoplasm Invasiveness; Neoplasm Metastasis; Proto-Oncogene Proteins c-akt; Receptor for Advanced Glycation End Products; Signal Transduction; Tumor Microenvironment; Xenograft Model Antitumor Assays

Topics: Breast Neoplasms; CD36 Antigens; Cell Communication; Cell Differentiation; Endothelial Cells; Female; Humans; Lysophospholipids; Neoplastic Stem Cells; Protein Kinase C; Signal Transduction; Stem Cell Niche; Tumor Microenvironment

Topics: Breast Neoplasms; Cell Differentiation; Down-Regulation; Female; Gene Expression Regulation, Leukemic; HL-60 Cells; Humans; K562 Cells; Leukemia; Lysophospholipids; MCF-7 Cells; Myeloid Cells; Neoplasm Proteins; NM23 Nucleoside Diphosphate Kinases; Receptors, Lysophosphatidic Acid; Tretinoin; U937 Cells; Up-Regulation

Topics: Adult; Aged; Biomarkers, Tumor; Breast Neoplasms; Disease-Free Survival; Female; Humans; Lysophospholipids; Middle Aged; Phosphoric Diester Hydrolases; Prognosis; Signal Transduction

Topics: Amphiregulin; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cell Movement; Cell Proliferation; Drug Screening Assays, Antitumor; Enhancer of Zeste Homolog 2 Protein; Epithelial-Mesenchymal Transition; Female; Fluorouracil; Gene Expression Regulation, Neoplastic; Humans; Lysophospholipids; MCF-7 Cells; Neoplasm Invasiveness; Phosphorylation; Resveratrol; RNA, Small Interfering; Signal Transduction; Y-Box-Binding Protein 1

Topics: Apoptosis; Arrestins; beta-Arrestins; Blotting, Western; Breast; Breast Neoplasms; Carcinoma, Intraductal, Noninfiltrating; Cell Adhesion; Cell Movement; Cell Proliferation; Cells, Cultured; Chemotaxis; Female; Humans; Immunoenzyme Techniques; Lysophospholipids; Neoplasm Invasiveness; Neoplasm Staging; ras GTPase-Activating Proteins; Real-Time Polymerase Chain Reaction; Receptors, Lysophosphatidic Acid; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; RNA, Small Interfering; Shelterin Complex; Signal Transduction; Telomere-Binding Proteins

Topics: Breast Neoplasms; Cell Line, Tumor; Cell Migration Assays; Cell Movement; Disease Progression; Epidermal Growth Factor; Female; Humans; Lysophospholipids; Neoplasm Metastasis; Phenotype; Tumor Stem Cell Assay

Topics: Breast Neoplasms; Cell Adhesion; Cell Line, Tumor; Cell Movement; Cell Shape; Chemotaxis; Enzyme Activation; Extracellular Matrix; Female; Focal Adhesion Kinase 1; Focal Adhesions; Guanine Nucleotide Exchange Factors; Humans; Lysophospholipids; Myosin Light Chains; Neoplasm Invasiveness; Oncogene Proteins; Phosphorylation; Protein Binding; Protein Isoforms; Protein Processing, Post-Translational; Protein Transport; rhoA GTP-Binding Protein

Topics: Actins; Breast Neoplasms; Cell Line, Tumor; Cell Movement; Epidermal Growth Factor; Female; Hepatocyte Growth Factor; Humans; Lysophospholipids; Mitogen-Activated Protein Kinases; Myosin-Light-Chain Kinase; Myosins; Neoplasm Invasiveness; rac GTP-Binding Proteins; rho GTP-Binding Proteins; Signal Transduction

Topics: Animals; Biomarkers, Tumor; Breast Neoplasms; Cell Line, Tumor; Female; Gene Expression Regulation, Neoplastic; Heparin-binding EGF-like Growth Factor; Humans; Isoxazoles; Lysophospholipids; Male; Mice; Mice, Inbred BALB C; Mice, Nude; Propionates; Prostatic Neoplasms; Receptors, Lysophosphatidic Acid; RNA, Messenger; Signal Transduction; Xenograft Model Antitumor Assays

Topics: Animals; Blood Platelets; Bone and Bones; Bone Neoplasms; Breast; Breast Neoplasms; Cell Line, Tumor; Cell Movement; Cell Proliferation; Female; Humans; Integrin alphaVbeta3; Lysophospholipids; Mice, Inbred BALB C; Mice, Nude; Neoplasm Invasiveness; Phosphoric Diester Hydrolases; Platelet Activation

Topics: Antineoplastic Agents; Breast Neoplasms; Cell Movement; Cell Proliferation; Curcumin; Female; Gene Expression Regulation, Neoplastic; Humans; Lysophospholipids; Matrix Metalloproteinases; MCF-7 Cells; Neoplasm Invasiveness; rho-Associated Kinases; rhoA GTP-Binding Protein; Signal Transduction

Topics: Animals; Breast Neoplasms; Cell Line, Tumor; Female; Heterografts; Homeodomain Proteins; Humans; Lysophospholipids; Mice; Mice, Inbred BALB C; Mice, Nude; MicroRNAs; Neoplasm Metastasis; Receptors, Lysophosphatidic Acid; Signal Transduction; Transcription Factors; Transfection; Zinc Finger E-box-Binding Homeobox 1

Topics: Animals; Breast Neoplasms; Cell Line, Tumor; Cytokines; Disease Models, Animal; Doxycycline; Female; Humans; Inflammation; Inflammation Mediators; Lysophospholipids; Macrophages; Mice; Neovascularization, Pathologic; NF-kappa B; Phosphorylation; Protein Transport; Tumor Burden; Xenograft Model Antitumor Assays

Topics: Animals; Breast Neoplasms; Carcinogenesis; CD36 Antigens; Cell Proliferation; Cells, Cultured; Diet; Disease Models, Animal; Endothelium, Vascular; Female; Humans; Lysophospholipids; Mice; Mice, Inbred C57BL; Obesity; Protein Kinase C; Receptors, Estrogen; Risk; Signal Transduction; Vascular Remodeling

Topics: Blotting, Western; Breast Neoplasms; Cell Movement; Cell Proliferation; Chemotaxis; Colonic Neoplasms; ErbB Receptors; Humans; Interleukin-6; Interleukin-8; Lysophospholipids; Neoplasm Invasiveness; Phosphotransferases (Alcohol Group Acceptor); Receptors, Lysophosphatidic Acid; Receptors, Lysosphingolipid; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Sphingosine; Stomach Neoplasms; Transcriptional Activation; Tumor Cells, Cultured; Up-Regulation; Urokinase-Type Plasminogen Activator

Topics: Apoptosis; Blotting, Western; Breast Neoplasms; Cell Cycle; Cell Line, Tumor; Ceramides; Humans; Lysophosphatidylcholines; Lysophospholipids; Melanoma; Membrane Potential, Mitochondrial; Multienzyme Complexes; Paclitaxel; Phosphodiesterase I; Phosphoric Diester Hydrolases; Pyrophosphatases; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger

Topics: Anilides; Blotting, Western; Breast Neoplasms; Catalysis; Cell Line; Cell Line, Tumor; Cell Movement; Enzyme Inhibitors; Humans; Kinetics; Lysophosphatidylcholines; Lysophospholipids; Melanoma; Multienzyme Complexes; Organophosphates; Organophosphonates; Phosphodiesterase I; Phosphoric Diester Hydrolases; Pyridines; Pyrophosphatases; Receptors, Lysophosphatidic Acid; Reverse Transcriptase Polymerase Chain Reaction; RNA Interference; RNA, Small Interfering; Transfection

Topics: Breast Neoplasms; Cell Line, Tumor; Cell Movement; Female; Humans; Lysophospholipids; Multienzyme Complexes; Organophosphonates; Phosphodiesterase I; Phosphoric Diester Hydrolases; Pyrophosphatases; Receptors, Lysophosphatidic Acid

Topics: Bone Marrow Cells; Breast Neoplasms; Cell Adhesion; Cell Movement; Cell Proliferation; Cells, Cultured; Chemokine CCL2; Chemokine CXCL1; Endothelium, Vascular; Enzyme-Linked Immunosorbent Assay; Extracellular Signal-Regulated MAP Kinases; Female; Granulocyte-Macrophage Colony-Stimulating Factor; Humans; Interleukin-6; Interleukin-8; Lysophospholipids; Neovascularization, Physiologic; Osteoclasts; Phosphatidylinositol 3-Kinases; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Sphingosine; Umbilical Veins; Vascular Endothelial Growth Factor A

Topics: Animals; Breast Neoplasms; Colonic Neoplasms; Endothelium, Vascular; Female; Humans; Immunoenzyme Techniques; Lung Neoplasms; Lysophospholipids; Melanoma; Mice; Mice, SCID; Neoplasm Transplantation; Receptors, Lysophosphatidic Acid; Receptors, Lysosphingolipid; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Sphingosine; Transplantation, Heterologous; Tumor Cells, Cultured; Umbilical Cord

Topics: Acetylcysteine; Breast Neoplasms; Cell Line, Tumor; Cell Movement; Cell Proliferation; Dose-Response Relationship, Drug; Extracellular Signal-Regulated MAP Kinases; Female; Humans; Lysophospholipids; Neoplasm Metastasis; p21-Activated Kinases; Phosphatidylinositol 3-Kinases; Reactive Oxygen Species; Signal Transduction

Topics: Amides; Animals; Breast Neoplasms; Cell Line, Tumor; Cell Movement; Enzyme Inhibitors; Female; Heterocyclic Compounds, 4 or More Rings; Lysophospholipids; Mice; Myosin Light Chains; Pertussis Toxin; Phosphorylation; Pyridines; Receptors, Lysophosphatidic Acid; rho-Associated Kinases; rhoA GTP-Binding Protein; RNA, Small Interfering; Signal Transduction

Topics: Apoptosis; Breast Neoplasms; Cell Line, Tumor; Drug Resistance, Neoplasm; G2 Phase; Humans; Lysophospholipids; Mitosis; Multienzyme Complexes; Paclitaxel; Phosphodiesterase I; Phosphoric Diester Hydrolases; Pyrophosphatases; Signal Transduction

Topics: Breast Neoplasms; Cell Line, Tumor; Cyclin-Dependent Kinase Inhibitor p21; Drug Synergism; Female; Humans; Immunohistochemistry; Lysophospholipids; Ovarian Neoplasms; Phosphorylation; Transforming Growth Factor beta

Topics: Antibodies; Breast Neoplasms; Cell Line, Tumor; Cell Movement; Female; Flavonoids; Focal Adhesion Kinase 1; Gene Expression Regulation, Neoplastic; Humans; Intercellular Signaling Peptides and Proteins; Lysophospholipids; MAP Kinase Signaling System; Neoplasm Invasiveness; Progranulins; RNA, Small Interfering; Transfection

Topics: Animals; Blood Platelets; Bone and Bones; Bone Neoplasms; Bone Resorption; Breast Neoplasms; Cell Line; Cell Line, Tumor; Cell Proliferation; Cricetinae; Culture Media; Cytokines; Disease Progression; Dose-Response Relationship, Drug; Doxycycline; Enzyme-Linked Immunosorbent Assay; Female; Humans; Immunohistochemistry; Interleukin-6; Interleukin-8; Ki-67 Antigen; Lysophospholipids; Mice; Mice, Inbred BALB C; Mice, Nude; Mitogens; Models, Biological; Neoplasm Metastasis; Osteoclasts; Osteolysis; Phospholipase D; Platelet Activation; Platelet Aggregation; Reverse Transcriptase Polymerase Chain Reaction; RNA; Time Factors; Transfection

Topics: Animals; Blotting, Western; Breast Neoplasms; Cell Line, Tumor; Cell Membrane; Cytosol; Female; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Humans; Lung Neoplasms; Lysophospholipids; Mammary Neoplasms, Experimental; Mice; Mice, Nude; Naphthoquinones; Protein Transport; ras Proteins; Reverse Transcriptase Polymerase Chain Reaction; rho GTP-Binding Proteins; rhoA GTP-Binding Protein; rhoC GTP-Binding Protein; RNA, Messenger; Signal Transduction; Stress Fibers; Xenograft Model Antitumor Assays

Topics: Breast Neoplasms; Cell Line, Tumor; Chemotaxis; DNA-Binding Proteins; Female; Gene Expression Regulation; Glucose-6-Phosphate Isomerase; Glycoproteins; Humans; Integrin alpha6beta4; Lysophospholipids; Multienzyme Complexes; NFATC Transcription Factors; Nuclear Proteins; Oligonucleotide Array Sequence Analysis; Phosphatidylcholines; Phosphodiesterase I; Phosphoric Diester Hydrolases; Pyrophosphatases; Transcription Factors

Topics: Anoikis; Breast Neoplasms; Caspase 3; Caspase 9; Caspases; Cell Line, Tumor; Cell Proliferation; Epidermal Growth Factor; Epithelial Cells; Genes, Dominant; Humans; Lysophospholipids; Neoplasm Invasiveness; p21-Activated Kinases; Phosphorylation; Plasmids; Poly(ADP-ribose) Polymerases; Protein Serine-Threonine Kinases; Protein Structure, Tertiary; Signal Transduction; Time Factors; Transfection

Topics: Animals; Blotting, Western; Breast Neoplasms; Bromodeoxyuridine; Cells, Cultured; Chickens; DNA; Endothelins; ErbB Receptors; Fibroblasts; Growth Hormone; Humans; Immunoprecipitation; Lysophospholipids; Mice; Mice, Inbred C3H; Peptide Fragments; Phosphorylation; Proto-Oncogene Proteins pp60(c-src); S Phase; STAT5 Transcription Factor; Trans-Activators; Tyrosine

Topics: Breast Neoplasms; Cell Line, Tumor; Chemotaxis; Dose-Response Relationship, Drug; Enzyme Activation; Female; Gene Expression Regulation, Neoplastic; Humans; Isoxazoles; Lysophospholipids; Neoplasm Invasiveness; Propionates; Protein Isoforms; Receptors, Lysophosphatidic Acid; rho GTP-Binding Proteins; RNA Interference; RNA, Messenger; RNA, Small Interfering; Signal Transduction

Topics: Animals; Antineoplastic Agents; Benzenesulfonamides; Breast Neoplasms; Cell Line, Tumor; Drug Resistance, Neoplasm; Female; Humans; Lung; Lung Neoplasms; Melanoma; Mice; Models, Molecular; Neoplasm Invasiveness; Neoplastic Stem Cells; Phosphodiesterase Inhibitors; Phosphoric Diester Hydrolases; Structure-Activity Relationship; Sulfonamides