Page last updated: 2024-08-26

lysophosphatidic acid and Atherogenesis

lysophosphatidic acid has been researched along with Atherogenesis in 22 studies

Research

Studies (22)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (4.55)29.6817
2010's20 (90.91)24.3611
2020's1 (4.55)2.80

Authors

AuthorsStudies
Chattopadhyay, A; Fogelman, AM; Reddy, ST1
Kamato, D; Little, PJ; Ta, HT; Xu, S; Zhou, Y1
Chen, L; Deng, X; Liu, Y; Yang, X; Yu, C; Zhang, J1
Guo, T; Li, F; Shen, X; Zhang, T; Zou, J1
Angel, PM; Drake, RR; Fang, XF; Kraemer, M; Morris, AJ; Smyth, SS; Yang, L1
Akamine, T; Ishizawa, S; Kanazawa, Y; Kawanami, D; Matoba, K; Nagai, Y; Takeda, Y; Utsunomiya, K; Yokota, T1
Brandon, JA; Morris, AJ; Mueller, P; Smyth, SS; Yang, F1
Bao, S; Day, R; Tan, C; Turk, J; Zhao, QD1
Getz, GS; Reardon, CA1
Anantharamaiah, GM; Chattopadhyay, A; Faull, KF; Fogelman, AM; Fogelman, SI; Grijalva, V; Hough, G; Hwang, LH; Meriwether, D; Navab, M; Reddy, ST; Su, F; Wagner, AC1
Morris, A; Mueller, P; Smyth, SS; Ye, S1
Abdel-Latif, A; Heron, PM; Morris, AJ; Smyth, SS1
Bot, I; Kritikou, E; Kröner, MJ; Kuiper, J; Schaftenaar, FH; Swart, M; van der Heijden, T; van Puijvelde, GH; van Santbrink, PJ1
Cong, YN; Li, ZG; Sun, HR; Wang, PF; Wu, QZ; Zhang, JB; Zhang, JS1
Biessen, EA; Bot, I; Bot, M; David, S; Helms, JB; Lopez-Vales, R; Saulnier-Blache, JS; van Berkel, TJ; van de Lest, CH1
Brandl, R; Khandoga, AL; Pandey, D; Siess, W; Welsch, U1
Anantharamaiah, GM; Fogelman, AM; Hama, S; Hough, G; Imaizumi, S; Navab, M; Reddy, ST1
Chun, J; Globke, B; Heyll, K; Karshovska, E; Megens, R; Reinholz, M; Saulnier-Blache, JS; Schober, A; Sevilmis, G; Soehnlein, O; Subramanian, P; van Zandvoort, M; Weber, C; Zhou, Z1
Chai, H; Chen, C; Kagan, A; Liang, Z; Lin, PH; Ochoa, LN; Yao, Q1
Schober, A; Siess, W1
Anantharamaiah, GM; Chattopadhyay, A; Farias-Eisener, R; Farias-Eisner, R; Fogelman, AM; Gao, F; Grijalva, V; Hough, G; Meriwether, D; Namiri-Kalantari, R; Navab, M; Palgnachari, MN; Reddy, ST; Springstead, JR; Su, F; Van Lenten, BJ; Wagner, AC1
Calay, D; Delaive, E; Dieu, M; Gustin, C; Raes, M1

Reviews

7 review(s) available for lysophosphatidic acid and Atherogenesis

ArticleYear
The multiple roles of lysophosphatidic acid in vascular disease and atherosclerosis.
    Current opinion in lipidology, 2023, 10-01, Volume: 34, Issue:5

    Topics: Atherosclerosis; Endothelial Cells; Humans; Intestine, Small; Lysophospholipids

2023
Lysophosphatidic acid and its receptors: pharmacology and therapeutic potential in atherosclerosis and vascular disease.
    Pharmacology & therapeutics, 2019, Volume: 204

    Topics: Animals; Atherosclerosis; Humans; Lysophospholipids; Receptors, Lysophosphatidic Acid; Signal Transduction; Vascular Diseases

2019
Arguing the case for the autotaxin-lysophosphatidic acid-lipid phosphate phosphatase 3-signaling nexus in the development and complications of atherosclerosis.
    Arteriosclerosis, thrombosis, and vascular biology, 2014, Volume: 34, Issue:3

    Topics: Adipose Tissue; Animals; Apolipoproteins E; Atherosclerosis; Coronary Artery Disease; Genetic Predisposition to Disease; Humans; Lysophospholipids; Mice; Mice, Knockout; Phosphatidate Phosphatase; Phosphoric Diester Hydrolases; Plaque, Atherosclerotic; Risk; Sphingosine

2014
The structure/function of apoprotein A-I mimetic peptides: an update.
    Current opinion in endocrinology, diabetes, and obesity, 2014, Volume: 21, Issue:2

    Topics: Anti-Inflammatory Agents; Antioxidants; Apolipoprotein A-I; Atherosclerosis; Biomimetic Materials; Diet; Female; Humans; Inflammation; Intestine, Small; Lysophospholipids; Male; Plants, Genetically Modified; Solanum lycopersicum; Structure-Activity Relationship

2014
Lysophospholipid mediators in the vasculature.
    Experimental cell research, 2015, May-01, Volume: 333, Issue:2

    Topics: Animals; Atherosclerosis; Blood Vessels; Cell Communication; Humans; Lysophospholipids; Phosphoric Diester Hydrolases; Receptors, Lysophosphatidic Acid; Signal Transduction

2015
Lysophospholipids in coronary artery and chronic ischemic heart disease.
    Current opinion in lipidology, 2015, Volume: 26, Issue:5

    Topics: Animals; Atherosclerosis; Coronary Artery Disease; Humans; Lysophospholipids; Myocardial Ischemia; Signal Transduction; Sphingosine

2015
Lysophosphatidic acid in atherosclerotic diseases.
    British journal of pharmacology, 2012, Volume: 167, Issue:3

    Topics: Animals; Atherosclerosis; Drug Design; Humans; Lysophospholipids; Signal Transduction; Thrombosis

2012

Other Studies

15 other study(ies) available for lysophosphatidic acid and Atherogenesis

ArticleYear
Lysophosphatidic acid decreased macrophage foam cell migration correlated with downregulation of fucosyltransferase 8 via HNF1α.
    Atherosclerosis, 2019, Volume: 290

    Topics: Animals; Atherosclerosis; Cell Movement; Disease Models, Animal; Down-Regulation; Foam Cells; Fucosyltransferases; HEK293 Cells; Hepatocyte Nuclear Factor 1-alpha; Humans; Lysophospholipids; Macrophage Activation; Male; Mice; Mice, Inbred C57BL; Mice, Knockout, ApoE; Protein Processing, Post-Translational; RAW 264.7 Cells; Receptors, Lysophosphatidic Acid; Signal Transduction

2019
Lysophosphatidic acid enhances neointimal hyperplasia following vascular injury through modulating proliferation, autophagy, inflammation and oxidative stress.
    Molecular medicine reports, 2018, Volume: 18, Issue:1

    Topics: Animals; Atherosclerosis; Cell Proliferation; Hyperplasia; Inflammation; Lysophospholipids; Male; Neointima; Oxidative Stress; Rats; Rats, Sprague-Dawley

2018
LPA receptor 4 deficiency attenuates experimental atherosclerosis.
    Journal of lipid research, 2019, Volume: 60, Issue:5

    Topics: Animals; Atherosclerosis; Cells, Cultured; Lysophospholipids; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Receptors, Purinergic

2019
ROCK2 Regulates Monocyte Migration and Cell to Cell Adhesion in Vascular Endothelial Cells.
    International journal of molecular sciences, 2019, Mar-16, Volume: 20, Issue:6

    Topics: Actin Cytoskeleton; Active Transport, Cell Nucleus; Aorta; Atherosclerosis; Cell Adhesion; Cell Movement; Chemokine CCL2; E-Selectin; Endothelial Cells; Gene Expression Regulation; Humans; I-kappa B Kinase; Lysophospholipids; Monocytes; Phosphorylation; rho-Associated Kinases; Signal Transduction; Transcription Factor RelA

2019
Group VIA phospholipase A2 mediates enhanced macrophage migration in diabetes mellitus by increasing expression of nicotinamide adenine dinucleotide phosphate oxidase 4.
    Arteriosclerosis, thrombosis, and vascular biology, 2014, Volume: 34, Issue:4

    Topics: Animals; Atherosclerosis; Cell Movement; Cells, Cultured; Diabetes Mellitus; Diet, High-Fat; Disease Models, Animal; Disease Progression; Enzyme Inhibitors; Group VI Phospholipases A2; Hydrogen Peroxide; Lysophospholipids; Macrophages, Peritoneal; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; NADPH Oxidase 4; NADPH Oxidases; Oligonucleotides, Antisense; Receptors, LDL; Signal Transduction; Stress, Physiological; Time Factors; Transfection; Up-Regulation

2014
Source and role of intestinally derived lysophosphatidic acid in dyslipidemia and atherosclerosis.
    Journal of lipid research, 2015, Volume: 56, Issue:4

    Topics: Animals; Aorta; Atherosclerosis; Benzoxazoles; Dietary Fats; Dyslipidemias; Female; Group IB Phospholipases A2; Intestinal Absorption; Intestinal Mucosa; Intestines; Jejunum; Liver; Lysophosphatidylcholines; Lysophospholipids; Male; Mice; Phosphoric Diester Hydrolases; Piperazines; Receptors, LDL

2015
Inhibition of lysophosphatidic acid receptors 1 and 3 attenuates atherosclerosis development in LDL-receptor deficient mice.
    Scientific reports, 2016, 11-24, Volume: 6

    Topics: Animals; Atherosclerosis; Cholesterol, LDL; Disease Models, Animal; Endocytosis; Humans; Isoxazoles; Lysophospholipids; Mice; Propionates; Receptors, LDL; Receptors, Lysophosphatidic Acid; Signal Transduction

2016
Plasma Phospholipids are Associated with Mild Cognitive Impairment in Type 2 Diabetic Patients.
    Current Alzheimer research, 2017, Volume: 14, Issue:6

    Topics: Aged; Aged, 80 and over; Ankle Brachial Index; Atherosclerosis; C-Reactive Protein; Carotid Intima-Media Thickness; Cognitive Dysfunction; Cross-Sectional Studies; Diabetes Mellitus, Type 2; Female; Glycated Hemoglobin; Humans; Lysophospholipids; Male; Middle Aged; Neuropsychological Tests; Phospholipids; Retrospective Studies

2017
Atherosclerotic lesion progression changes lysophosphatidic acid homeostasis to favor its accumulation.
    The American journal of pathology, 2010, Volume: 176, Issue:6

    Topics: Acyltransferases; Animals; Atherosclerosis; Carotid Arteries; Diet; Disease Progression; Gene Expression Profiling; Group VI Phospholipases A2; Homeostasis; Humans; Lysophospholipids; Male; Mice; Mice, Knockout; Molecular Sequence Data; Receptors, LDL

2010
GPR92/LPA₅ lysophosphatidate receptor mediates megakaryocytic cell shape change induced by human atherosclerotic plaques.
    Cardiovascular research, 2011, Apr-01, Volume: 90, Issue:1

    Topics: Atherosclerosis; Cell Line; Cell Shape; Humans; Lipid Metabolism; Lysophospholipids; Megakaryocytes; Microscopy, Electron, Scanning; Nephelometry and Turbidimetry; Receptors, Lysophosphatidic Acid; Reverse Transcriptase Polymerase Chain Reaction; rho-Associated Kinases; RNA Interference; Time Factors; Transfection

2011
Intestine may be a major site of action for the apoA-I mimetic peptide 4F whether administered subcutaneously or orally.
    Journal of lipid research, 2011, Volume: 52, Issue:6

    Topics: Administration, Cutaneous; Administration, Oral; Amino Acid Sequence; Animals; Apolipoprotein A-I; Apolipoproteins E; Atherosclerosis; Diet; Disease Models, Animal; Dose-Response Relationship, Drug; Feces; Female; Gene Deletion; Inflammation; Intestinal Mucosa; Lipoproteins, HDL; Liver; Lysophospholipids; Mice; Mice, Knockout; Molecular Mimicry; Molecular Sequence Data; Peptides; Serum Amyloid A Protein

2011
Lipoprotein-derived lysophosphatidic acid promotes atherosclerosis by releasing CXCL1 from the endothelium.
    Cell metabolism, 2011, May-04, Volume: 13, Issue:5

    Topics: Animals; Apolipoproteins E; Atherosclerosis; Carotid Arteries; Cells, Cultured; Chemokine CXCL1; Diet, Atherogenic; Endothelium, Vascular; Hyperlipidemias; Lipoproteins, LDL; Lysophospholipids; Macrophages; Mice; Mice, Inbred C57BL; Mice, Knockout; Monocytes; Receptors, Lysophosphatidic Acid; RNA, Small Interfering

2011
Lysophosphatidic acid causes endothelial dysfunction in porcine coronary arteries and human coronary artery endothelial cells.
    Atherosclerosis, 2012, Volume: 222, Issue:1

    Topics: Animals; Atherosclerosis; Bradykinin; Coronary Vessels; Down-Regulation; Endothelium, Vascular; Humans; Lysophospholipids; Membrane Potential, Mitochondrial; Nitric Oxide Synthase Type III; Oxidative Stress; Selenomethionine; Superoxide Dismutase; Superoxide Dismutase-1; Superoxides; Swine; Vasodilation

2012
A novel approach to oral apoA-I mimetic therapy.
    Journal of lipid research, 2013, Volume: 54, Issue:4

    Topics: Animals; Apolipoprotein A-I; Apolipoproteins E; Atherosclerosis; Cholesterol; Female; Hydroxyeicosatetraenoic Acids; Intestine, Small; Lysophospholipids; Mice; Mice, Inbred C57BL; Mice, Knockout; Peptides; Plants, Genetically Modified; Receptors, LDL; Solanum lycopersicum; Triglycerides

2013
Upregulation of pentraxin-3 in human endothelial cells after lysophosphatidic acid exposure.
    Arteriosclerosis, thrombosis, and vascular biology, 2008, Volume: 28, Issue:3

    Topics: Analysis of Variance; Atherosclerosis; C-Reactive Protein; Cells, Cultured; Endothelial Cells; Gene Expression Regulation; Humans; Immunoblotting; Lysophospholipids; Probability; Receptors, Lysophosphatidic Acid; RNA, Messenger; Sensitivity and Specificity; Serum Amyloid P-Component; Umbilical Veins; Up-Regulation

2008