lysophosphatidic acid and Angiogenesis, Pathologic

Topics: Humans; Lysophospholipids; Molecular Targeted Therapy; Neovascularization, Pathologic; Phospholipids; Phosphoric Diester Hydrolases; Receptors, Lysophosphatidic Acid; Signal Transduction

Topics: Animals; Cell Movement; Humans; Lysophospholipids; Neoplasms; Neovascularization, Pathologic; Sphingosine

Topics: Endothelium, Vascular; Gene Expression Regulation; Humans; Lysophospholipids; Neovascularization, Pathologic; Neovascularization, Physiologic

Topics: Animals; Brain Neoplasms; Cell Movement; Glioblastoma; Humans; Lysophospholipids; Neovascularization, Pathologic; Signal Transduction

Topics: Animals; Bone Neoplasms; Carcinogenesis; Humans; Lysophospholipids; Neovascularization, Pathologic; Phosphoric Diester Hydrolases; Receptors, Lysophosphatidic Acid; Signal Transduction

Topics: Animals; Antineoplastic Agents; Cell Hypoxia; Cyclooxygenase 2; Diterpenes; Female; Humans; Interleukins; Intracellular Signaling Peptides and Proteins; Lysophospholipids; Membrane Lipids; Mice; Multienzyme Complexes; Neoplasm Invasiveness; Neoplasm Metastasis; Neoplasm Proteins; Neovascularization, Pathologic; Ovarian Neoplasms; Peptide Hydrolases; Phosphodiesterase I; Phospholipases A; Phosphoric Diester Hydrolases; Pyrophosphatases; Receptors, Lysophosphatidic Acid; Signal Transduction; Sphingosine; Vascular Endothelial Growth Factor A

Topics: Animals; Disease Progression; Drug Resistance, Neoplasm; Female; Humans; Intercellular Signaling Peptides and Proteins; Lysophospholipids; Male; Mice; Multienzyme Complexes; Neoplasm Metastasis; Neoplasms; Neovascularization, Pathologic; Phosphatidate Phosphatase; Phosphodiesterase I; Phospholipase D; Phosphoric Diester Hydrolases; Pyrophosphatases; Signal Transduction; Sphingosine

Topics: Blood Platelets; Bone and Bones; Breast Neoplasms; Cell Line, Tumor; Disease Progression; Female; Humans; Lysophospholipids; Models, Biological; Neoplasm Metastasis; Neovascularization, Pathologic; Osteolysis; Ovarian Neoplasms

Topics: Animals; Antigens, CD; Cadherins; Cell Communication; Cell Line, Tumor; Cell Membrane; Cell Proliferation; Drug Delivery Systems; Endothelial Cells; Lysophospholipids; Mice; Neoplasms; Neovascularization, Pathologic; Receptors, Lysophosphatidic Acid; Signal Transduction

Topics: Animals; Antigen Presentation; Antineoplastic Agents; Apolipoprotein A-I; Apolipoprotein A-II; Carcinogenesis; Cardiotonic Agents; Cell Line, Tumor; Cell Proliferation; Dendritic Cells; Female; Humans; Immunity; Immunocompetence; Lipoproteins, HDL; Lysophospholipids; Macrophages; Male; Matrix Metalloproteinase 9; Mice; Neoplasm Metastasis; Neoplasms; Neovascularization, Pathologic; Remission Induction; Survival Analysis; Tumor Microenvironment

Topics: Angiogenesis Inducing Agents; Aryl Hydrocarbon Receptor Nuclear Translocator; Cell Line, Tumor; HEK293 Cells; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; Lysophospholipids; Male; Neoplasm Metastasis; Neovascularization, Pathologic; Prostatic Neoplasms; Receptors, Aryl Hydrocarbon; Signal Transduction; Vascular Endothelial Growth Factor A

Topics: 3T3 Cells; Animals; Cell Movement; Endothelial Cells; Fibroblasts; Gene Expression Regulation, Neoplastic; Humans; Lung Neoplasms; Lysophospholipids; Mice; Neoplasm Invasiveness; Neoplasm Metastasis; Neoplasms, Experimental; Neovascularization, Pathologic; Receptors, Lysophosphatidic Acid; Signal Transduction; Vascular Endothelial Growth Factor A

Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Blotting, Western; Cell Line, Tumor; Cell Movement; Cell Proliferation; Humans; Lysophospholipids; Male; Melanoma, Experimental; Mice, Inbred C57BL; Microscopy, Confocal; Neoplasm Transplantation; Neovascularization, Pathologic; Protein Kinase Inhibitors; Reverse Transcriptase Polymerase Chain Reaction; rho-Associated Kinases; Tumor Burden

Topics: Animals; Carcinoma, Lewis Lung; CD36 Antigens; Cell Nucleus; Cells, Cultured; Cellular Reprogramming; Down-Regulation; Endothelial Cells; Ephrin-B2; Forkhead Box Protein O1; Histone Deacetylases; Humans; Lysophospholipids; Mice; Neovascularization, Pathologic; Neovascularization, Physiologic; Protein Kinase C; RNA Interference; Transcription, Genetic; Transfection

Topics: Animals; Breast Neoplasms; Cell Line, Tumor; Cytokines; Disease Models, Animal; Doxycycline; Female; Humans; Inflammation; Inflammation Mediators; Lysophospholipids; Macrophages; Mice; Neovascularization, Pathologic; NF-kappa B; Phosphorylation; Protein Transport; Tumor Burden; Xenograft Model Antitumor Assays

Topics: Cell Line, Tumor; Female; Gene Expression Regulation, Neoplastic; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; Lysophospholipids; Models, Biological; Neovascularization, Pathologic; Ovarian Neoplasms; Phosphorylation; Promoter Regions, Genetic; Proto-Oncogene Proteins c-myc; RNA, Small Interfering; Sp1 Transcription Factor; Vascular Endothelial Growth Factor A

Topics: Amino Acid Sequence; Angiogenesis Inhibitors; Animals; Apolipoprotein A-I; Blood Vessels; Cell Line, Tumor; Cell Movement; Cell Proliferation; Cell Survival; Cells, Cultured; Endothelial Cells; Extracellular Signal-Regulated MAP Kinases; Female; Fibroblast Growth Factor 2; Gene Expression; Humans; Intercellular Signaling Peptides and Proteins; Lysophospholipids; Mice; Mice, Inbred C57BL; Models, Biological; Molecular Mimicry; Molecular Sequence Data; Neovascularization, Pathologic; Neovascularization, Physiologic; Ovarian Neoplasms; Peptide Fragments; Peptides; Phosphorylation; Proto-Oncogene Proteins c-akt; Receptor, Fibroblast Growth Factor, Type 1; Signal Transduction; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factor Receptor-2

Topics: Animals; Apolipoprotein A-I; Cell Line, Tumor; Cobalt; Extracellular Signal-Regulated MAP Kinases; Female; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; Insulin; Intercellular Signaling Peptides and Proteins; Lysophospholipids; Mice; Mice, Inbred C57BL; Neovascularization, Pathologic; Ovarian Neoplasms; Oxygen; Peptides; Peptidomimetics; Phosphorylation; Proteasome Endopeptidase Complex; Proteolysis; Proto-Oncogene Proteins c-akt; Reactive Oxygen Species; Ribosomal Protein S6 Kinases, 70-kDa; Transcription, Genetic

Topics: Animals; Cell Division; Cell Line, Tumor; Cyclin D1; DNA; Dose-Response Relationship, Drug; Enzyme-Linked Immunosorbent Assay; Female; Immunoblotting; Lysophospholipids; Macrophage Migration-Inhibitory Factors; Mice; Mice, Inbred BALB C; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Neovascularization, Pathologic; Phosphorylation; ras Proteins; Reverse Transcriptase Polymerase Chain Reaction; RNA Interference; RNA, Double-Stranded; RNA, Messenger; Signal Transduction; Time Factors; Transfection; Tyrosine; Up-Regulation; Vascular Endothelial Growth Factor A

Topics: Amino Acid Sequence; Animals; Base Sequence; Blotting, Northern; Bradykinin; Capillaries; Cell Line; COS Cells; DNA-Binding Proteins; Endothelial Cells; Endothelin-1; Endothelium, Vascular; Green Fluorescent Proteins; GTPase-Activating Proteins; Immunohistochemistry; Kruppel-Like Transcription Factors; Luciferases; Luminescent Proteins; Lysophospholipids; Mice; Models, Genetic; Molecular Sequence Data; Mutagenesis, Site-Directed; Neovascularization, Pathologic; NIH 3T3 Cells; Phylogeny; Plasmids; Platelet-Derived Growth Factor; Precipitin Tests; Promoter Regions, Genetic; Protein Binding; Protein Structure, Tertiary; RNA; RNA, Messenger; Signal Transduction; Tissue Distribution; Transcription Factors; Transcription, Genetic; Transfection; Two-Hybrid System Techniques

Topics: Allosteric Site; Binding Sites; Biosensing Techniques; Blotting, Western; Catalysis; Catalytic Domain; Cell Line; Cell Movement; DNA, Complementary; Dose-Response Relationship, Drug; Fluorescence Resonance Energy Transfer; Glucose-6-Phosphate Isomerase; Glycoproteins; Humans; Hydrolysis; Kinetics; Ligands; Lipid Metabolism; Lipids; Lysophosphatidylcholines; Lysophospholipids; Models, Chemical; Multienzyme Complexes; Mutagenesis; Neoplasm Metastasis; Neoplasms; Neovascularization, Pathologic; Phosphodiesterase I; Phospholipase D; Phosphoric Diester Hydrolases; Pyrophosphatases; Recombinant Fusion Proteins; Recombinant Proteins; Sphingosine; Transfection

Topics: Animals; Gene Expression Regulation, Developmental; Genetic Techniques; Heterozygote; Lysophospholipids; Mice; Mice, Knockout; Models, Genetic; Multienzyme Complexes; Neovascularization, Pathologic; Phenotype; Phosphodiesterase I; Phosphoric Diester Hydrolases; Pyrophosphatases; Recombinant Proteins; Signal Transduction; Time Factors

Topics: Blotting, Western; Cell Line, Tumor; Enzyme-Linked Immunosorbent Assay; Fluorescent Antibody Technique; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; Immunoprecipitation; Lysophospholipids; Neoplasm Invasiveness; Neoplasms; Neovascularization, Pathologic; Reverse Transcriptase Polymerase Chain Reaction; RNA, Small Interfering; Transfection; Vascular Endothelial Growth Factor A

Topics: Animals; Antineoplastic Agents; Female; Humans; Lysophospholipids; Mice; Mice, Inbred C57BL; Multienzyme Complexes; Neoplasm Metastasis; Neovascularization, Pathologic; Organophosphates; Phosphodiesterase I; Phosphodiesterase Inhibitors; Phosphoric Diester Hydrolases; Pyrophosphatases; Sphingosine