Compounds > lysine
Page last updated: 2024-08-17

lysine and Protein Aggregation, Pathological

lysine has been researched along with Protein Aggregation, Pathological in 13 studies

Research

Studies (13)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's9 (69.23)24.3611
2020's4 (30.77)2.80

Authors

AuthorsStudies
Buratti, E; Elsässer, SJ; Feederle, R; Garcia Morato, J; Gloeckner, CJ; Hans, F; Kahle, PJ; Neumann, M; Skodras, AA; von Zweydorf, F1
Legleiter, J; Nyman, M; Pilkington, AW; Schupp, J; Smith, DM; Valentine, SJ1
Gulick, J; McLendon, PM; Osinska, H; Robbins, J; Shay-Winkler, K; Xu, N; Yu, Y; Yutzey, KE1
Boulos, A; Ciechanover, A; Cohen-Rosenzweig, C; Hakim-Eshed, V; Kwon, YT; Phuc Nguyen, HH; Riess, O; Yu-Taeger, L; Ziv, NE; Ziv, T1
de Moraes, MC; Fernandes, L; Foguel, D; Grimster, NP; Kelly, JW; Magalhães, AV; Moraes, N; Palhano, FL; Romão, L; Sagrillo, FS1
Ambadipudi, S; Biernat, J; Mandelkow, E; Riedel, D; Zweckstetter, M1
Chang, CK; Chen, ME; Chen, WA; Chun, MC; How, SC; Li, CT; Lo, CH; Wang, SS; Wu, JW1
Alves, A; Braga, C; Cordeiro, Y; Cortines, J; Foguel, D; Graña-Montes, R; Pimenta, KM; Sant'Anna, R; Varejão, N; Ventura, S1
Cohen, TJ; Hwang, AW; Lee, VM; Restrepo, CR; Trojanowski, JQ; Yuan, CX1
Andres, CR; Arnoult, C; Blasco, H; Burlaud Gaillard, J; Corcia, P; Dangoumau, A; Marouillat, S; Uzbekov, R; Veyrat-Durebex, C; Vourc'h, P1
Burnouf, S; Dols, J; Gorsky, MK; Mandelkow, E; Partridge, L1
Bitan, G; Klärner, FG; Schrader, T1
Fedorov, O; Kessler, BM; Knapp, S; La Thangue, NB; Olzscha, H1

Other Studies

13 other study(ies) available for lysine and Protein Aggregation, Pathological

ArticleYear
Sirtuin-1 sensitive lysine-136 acetylation drives phase separation and pathological aggregation of TDP-43.
    Nature communications, 2022, 03-09, Volume: 13, Issue:1

    Topics: Acetylation; Amyotrophic Lateral Sclerosis; DNA-Binding Proteins; Humans; Lysine; Protein Aggregation, Pathological; Protein Processing, Post-Translational; RNA; Sirtuin 1

2022
Acetylation of Aβ
    ACS chemical neuroscience, 2020, 01-15, Volume: 11, Issue:2

    Topics: Acetylation; Alzheimer Disease; Amyloid beta-Peptides; Animals; Lipid Bilayers; Lysine; Mice; Peptide Fragments; Protein Aggregation, Pathological

2020
Ube2v1 Positively Regulates Protein Aggregation by Modulating Ubiquitin Proteasome System Performance Partially Through K63 Ubiquitination.
    Circulation research, 2020, 03-27, Volume: 126, Issue:7

    Topics: alpha-Crystallin B Chain; Animals; Animals, Newborn; Cells, Cultured; Female; Genome-Wide Association Study; Humans; Lysine; Male; Mice, Transgenic; Mutation; Myocytes, Cardiac; Proteasome Endopeptidase Complex; Protein Aggregation, Pathological; Rats; Transcription Factors; Ubiquitin-Conjugating Enzymes; Ubiquitination

2020
Site-specific ubiquitination of pathogenic huntingtin attenuates its deleterious effects.
    Proceedings of the National Academy of Sciences of the United States of America, 2020, 08-04, Volume: 117, Issue:31

    Topics: Animals; Brain; Cell Death; Cells, Cultured; Disease Models, Animal; Humans; Huntingtin Protein; Huntington Disease; Lysine; Neurons; Proteasome Endopeptidase Complex; Protein Aggregation, Pathological; Rats; Rats, Transgenic; Ubiquitination

2020
An ortho-Iminoquinone Compound Reacts with Lysine Inhibiting Aggregation while Remodeling Mature Amyloid Fibrils.
    ACS chemical neuroscience, 2017, 08-16, Volume: 8, Issue:8

    Topics: alpha-Synuclein; Amyloid beta-Peptides; Animals; Catechin; Cell Survival; Cells, Cultured; Chickens; Dopaminergic Neurons; HEK293 Cells; Humans; Lysine; Methionine; Mice; Micrococcus luteus; Microtubule-Associated Proteins; Muramidase; Neuroprotective Agents; Oxidation-Reduction; Peptide Fragments; Protein Aggregation, Pathological; Quinones; Tyrosine 3-Monooxygenase

2017
Liquid-liquid phase separation of the microtubule-binding repeats of the Alzheimer-related protein Tau.
    Nature communications, 2017, 08-17, Volume: 8, Issue:1

    Topics: Alternative Splicing; Alzheimer Disease; Amino Acid Sequence; Brain; Humans; Lysine; Magnetic Resonance Spectroscopy; Microscopy, Confocal; Microtubules; Phosphorylation; Protein Aggregation, Pathological; Protein Binding; Protein Isoforms; tau Proteins

2017
Effects of glycation on human γd-crystallin proteins by different glycation-inducing agents.
    International journal of biological macromolecules, 2018, Oct-15, Volume: 118, Issue:Pt A

    Topics: Cataract; Diabetes Complications; Fructosamine; Galactose; gamma-Crystallins; Glycation End Products, Advanced; Glycosylation; Humans; Lens, Crystalline; Lysine; Protein Aggregation, Pathological; Protein Denaturation; Pyruvaldehyde; Ribose

2018
The importance of a gatekeeper residue on the aggregation of transthyretin: implications for transthyretin-related amyloidoses.
    The Journal of biological chemistry, 2014, Oct-10, Volume: 289, Issue:41

    Topics: Amyloid; Amyloid Neuropathies, Familial; Gene Expression; Heparin; Humans; Leucine; Lysine; Mutation; Prealbumin; Protein Aggregation, Pathological; Protein Multimerization; Protein Stability; Protein Structure, Secondary; Protein Structure, Tertiary; Recombinant Proteins; Static Electricity

2014
An acetylation switch controls TDP-43 function and aggregation propensity.
    Nature communications, 2015, Jan-05, Volume: 6

    Topics: Acetylation; Amyotrophic Lateral Sclerosis; Cloning, Molecular; DNA Primers; DNA-Binding Proteins; Frontotemporal Lobar Degeneration; Humans; Immunohistochemistry; Immunoprecipitation; Lysine; Mass Spectrometry; Mutagenesis, Site-Directed; Oxidative Stress; Protein Aggregation, Pathological; Recombinant Proteins; Reverse Transcriptase Polymerase Chain Reaction; RNA, Small Interfering; Spinal Cord

2015
Inhibition of Pathogenic Mutant SOD1 Aggregation in Cultured Motor Neuronal Cells by Prevention of Its SUMOylation on Lysine 75.
    Neuro-degenerative diseases, 2016, Volume: 16, Issue:3-4

    Topics: Animals; Cell Line; Cell Survival; CHO Cells; Cricetulus; Green Fluorescent Proteins; HEK293 Cells; Humans; Lysine; Mice; Motor Neurons; Mutation; Protein Aggregation, Pathological; Protein Structure, Secondary; SUMO-1 Protein; Sumoylation; Superoxide Dismutase-1

2016
Acetylation mimic of lysine 280 exacerbates human Tau neurotoxicity in vivo.
    Scientific reports, 2016, Mar-04, Volume: 6

    Topics: Acetylation; Alzheimer Disease; Animals; Animals, Genetically Modified; Disease Models, Animal; Drosophila; Female; Humans; Lysine; Neurotoxins; Protein Aggregation, Pathological; Protein Processing, Post-Translational; tau Proteins

2016
Molecular tweezers for lysine and arginine - powerful inhibitors of pathologic protein aggregation.
    Chemical communications (Cambridge, England), 2016, Oct-15, Volume: 52, Issue:76

    Topics: Animals; Arginine; Humans; Lysine; Protein Aggregation, Pathological; Receptors, Artificial

2016
CBP/p300 Bromodomains Regulate Amyloid-like Protein Aggregation upon Aberrant Lysine Acetylation.
    Cell chemical biology, 2017, Jan-19, Volume: 24, Issue:1

    Topics: Acetylation; Amyloid; Humans; Huntingtin Protein; Lysine; p300-CBP Transcription Factors; Proteasome Endopeptidase Complex; Protein Aggregates; Protein Aggregation, Pathological

2017