Page last updated: 2024-08-17

lysine and Osteosarcoma

lysine has been researched along with Osteosarcoma in 25 studies

Research

Studies (25)

TimeframeStudies, this research(%)All Research%
pre-19901 (4.00)18.7374
1990's5 (20.00)18.2507
2000's7 (28.00)29.6817
2010's11 (44.00)24.3611
2020's1 (4.00)2.80

Authors

AuthorsStudies
Chang, SL; Fong, YC; Huang, YL; Ko, CY; Lai, CY; Lee, CW; Lin, ZC; Liu, JF; Liu, SC; Peng, KT; Tang, CH; Tsai, CH; Tsai, HC; Wang, SW; Yang, CY1
Achuthankutty, D; Borgermann, N; Guo, X; Haahr, P; Hoffmann, S; Mailand, N; Shearer, R; Sixma, TK; Typas, D1
Horejsi, Z; Lidak, T; Macurek, L; von Morgen, P1
Liu, M; Liu, W; Wang, W; Zhang, J1
Fan, M; Shi, X1
Dong, H; Sun, B; Wang, Y; Zhang, J; Zhang, Q1
Baas, R; Jansen, PW; Riss, A; Schram, AW; Timmers, HT; Tora, L; Vermeulen, M1
Cantó, C; Dominy, J; Puigserver, P1
Chen, X; Cheng, Y; Gong, Y; He, C; Li, D; Liu, J; Ma, H; Tian, H1
Gorlick, R; Hingorani, P; Kolb, EA; Lin, J; Piperdi, S; Pressman, L; Zhang, W1
Bielinsky, AK; Das-Bradoo, S; Haworth, JC; Nguyen, HD; Ricke, RM; Wood, JL1
Bartek, J; Bekker-Jensen, S; Fugger, K; Gromova, I; Lukas, C; Lukas, J; Mailand, N; Nerstedt, A; Rendtlew Danielsen, J1
Cloos, P; Gajhede, M; Helgstrand, C; Helin, K; Kastrup, JS; Kristensen, LH; Lees, M; Nielsen, AL; Olsen, L1
Ivanov, V; Kalinovsky, T; Niedzwiecki, A; Rath, M; Roomi, MW2
Ivanov, V; Kalinovsky, T; Niedzwiecki, A; Rath, M; Roomi, MW; Roomi, N1
Ahmed, K; Aikhionbare, F; Cheng, Z; Ding, X; Hu, R; Huang, H; Jin, C; Ke, Y; Liang, S; Liu, J; Liu, Z; Powell, M; Reddy, SE; Wang, F; Wang, H; Wang, W; Wu, Q; Xu, Y; Xue, Y; Yan, H; Yao, X; Yu, J1
Fredericks, WJ; Ivanov, AV; Maul, GG; Negorev, DG; Peng, H; Psulkowski, E; Rauscher, FJ; Sadofsky, MJ; Schultz, DC; White, DE; Yap, KL; Yurchenko, V; Zhou, MM1
Alloul-Ramdhani, M; Anvarian, Z; Baker, DA; Balog, CI; Deelder, AM; Hensbergen, PJ; Roukens, MG; Vertegaal, AC1
Bodo, M; Delling, G; Lehmann, HW; Müller, PK; Röser, K; Wolf, E1
Bruland, OS; Olafsen, T; Sandlie, I; Zalutsky, MR1
Nakajima, S; Ozono, K; Sakai, N; Yamagata, M1
Caulfield, MP; Chorev, M; Duong, LT; Gibbons, SW; Leu, CT; Rosenblatt, M; Roubini, E1
Abou-Samra, AB; Freeman, M; Jüppner, H; Segre, GV; Uneno, S1
Hersh, EM; Ohno, R1

Other Studies

25 other study(ies) available for lysine and Osteosarcoma

ArticleYear
IOX-1 suppresses metastasis of osteosarcoma by upregulating histone H3 lysine trimethylation.
    Biochemical pharmacology, 2023, Volume: 210

    Topics: Bone Neoplasms; Cisplatin; Histones; Humans; Lysine; Osteosarcoma

2023
ZUFSP Deubiquitylates K63-Linked Polyubiquitin Chains to Promote Genome Stability.
    Molecular cell, 2018, 04-05, Volume: 70, Issue:1

    Topics: Binding Sites; Bone Neoplasms; Cell Line, Tumor; Deubiquitinating Enzymes; DNA Damage; Genomic Instability; HEK293 Cells; Humans; Lysine; Osteosarcoma; Polyubiquitin; Protein Binding; Protein Interaction Domains and Motifs; Retinal Pigment Epithelium; Substrate Specificity; Ubiquitination

2018
Nuclear localisation of 53BP1 is regulated by phosphorylation of the nuclear localisation signal.
    Biology of the cell, 2018, Volume: 110, Issue:6

    Topics: Active Transport, Cell Nucleus; Arginine; Bone Neoplasms; Cell Nucleus; HEK293 Cells; Humans; Karyopherins; Lysine; Nuclear Localization Signals; Osteosarcoma; Phosphorylation; Protein Binding; Tumor Cells, Cultured; Tumor Suppressor p53-Binding Protein 1

2018
Ras-ERK1/2 signalling promotes the development of osteosarcoma through regulation of H4K12ac through HAT1.
    Artificial cells, nanomedicine, and biotechnology, 2019, Volume: 47, Issue:1

    Topics: Acetylation; Carcinogenesis; Cell Line, Tumor; Cell Proliferation; Down-Regulation; Enzyme Activation; Histone Acetyltransferases; Histones; Humans; Lysine; MAP Kinase Signaling System; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Osteosarcoma; Proteolysis; Proto-Oncogene Proteins c-mdm2; ras Proteins; Transcription, Genetic

2019
Tip60-dependent acetylation of KDM2B promotes osteosarcoma carcinogenesis.
    Journal of cellular and molecular medicine, 2019, Volume: 23, Issue:9

    Topics: Acetylation; Animals; Carcinogenesis; Cell Line, Tumor; F-Box Proteins; Gene Expression Regulation, Neoplastic; Heterografts; Histones; Humans; Jumonji Domain-Containing Histone Demethylases; Lysine; Lysine Acetyltransferase 5; Methylation; Mice; Osteosarcoma; Promoter Regions, Genetic; Protein Processing, Post-Translational

2019
p300 Acetylates JHDM1A to inhibit osteosarcoma carcinogenesis.
    Artificial cells, nanomedicine, and biotechnology, 2019, Volume: 47, Issue:1

    Topics: Acetylation; Animals; Apoptosis Regulatory Proteins; Carcinogenesis; Cyclin-Dependent Kinase Inhibitor p21; E1A-Associated p300 Protein; F-Box Proteins; Histones; Humans; Jumonji Domain-Containing Histone Demethylases; Lysine; Methylation; Mice; Nucleosomes; Osteosarcoma; Proto-Oncogene Proteins; Transcription, Genetic

2019
A dual role for SAGA-associated factor 29 (SGF29) in ER stress survival by coordination of both histone H3 acetylation and histone H3 lysine-4 trimethylation.
    PloS one, 2013, Volume: 8, Issue:7

    Topics: Acetylation; Acetyltransferases; Bone Neoplasms; Cell Line, Tumor; Cell Survival; Endoplasmic Reticulum Chaperone BiP; Endoplasmic Reticulum Stress; Gene Knockdown Techniques; Histones; Humans; Lysine; Methylation; Osteosarcoma; Promoter Regions, Genetic; Transcription Factor CHOP; Transcription, Genetic

2013
In vivo measurement of the acetylation state of sirtuin substrates as a proxy for sirtuin activity.
    Methods in molecular biology (Clifton, N.J.), 2013, Volume: 1077

    Topics: Acetylation; Animals; Bone Neoplasms; Cells, Cultured; Electron Transport Complex I; Humans; Immunoblotting; Immunoprecipitation; Lysine; Mice; Muscle, Skeletal; Osteosarcoma; Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha; Protein Processing, Post-Translational; Sirtuin 1; Sirtuin 3; Transcription Factors

2013
PLK1shRNA and doxorubicin co-loaded thermosensitive PLGA-PEG-PLGA hydrogels for osteosarcoma treatment.
    Biomaterials, 2014, Volume: 35, Issue:30

    Topics: Animals; Cell Cycle; Cell Cycle Proteins; Cell Death; Cell Line; Cell Survival; Doxorubicin; Gene Expression Regulation, Neoplastic; Humans; Hydrogels; In Situ Nick-End Labeling; Lactic Acid; Lysine; Male; Mice, Nude; Osteosarcoma; Phase Transition; Polo-Like Kinase 1; Polyethyleneimine; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Rats, Wistar; RNA, Small Interfering; Solutions; Tissue Distribution; Transfection

2014
Preclinical activity of palifosfamide lysine (ZIO-201) in pediatric sarcomas including oxazaphosphorine-resistant osteosarcoma.
    Cancer chemotherapy and pharmacology, 2009, Volume: 64, Issue:4

    Topics: Animals; Antineoplastic Agents; Base Sequence; Cell Line, Tumor; DNA Primers; Drug Resistance, Neoplasm; Female; Gene Expression; Humans; Ifosfamide; Lysine; Mice; Mice, SCID; Osteosarcoma; Reverse Transcriptase Polymerase Chain Reaction

2009
Defects in DNA ligase I trigger PCNA ubiquitylation at Lys 107.
    Nature cell biology, 2010, Volume: 12, Issue:1

    Topics: Bone Neoplasms; DNA Damage; DNA Helicases; DNA Ligase ATP; DNA Ligases; DNA Repair; DNA-Binding Proteins; DNA, Fungal; Gene Expression Regulation, Fungal; Humans; Lysine; Mutation; Osteosarcoma; Proliferating Cell Nuclear Antigen; S Phase; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Tumor Cells, Cultured; Ubiquitin; Ubiquitin-Conjugating Enzymes; Ubiquitin-Protein Ligases; Ubiquitination

2010
HERC2 coordinates ubiquitin-dependent assembly of DNA repair factors on damaged chromosomes.
    Nature cell biology, 2010, Volume: 12, Issue:1

    Topics: Bone Neoplasms; BRCA1 Protein; Carrier Proteins; Cells, Cultured; Chromosomes, Human; DNA Damage; DNA Repair; DNA-Binding Proteins; Guanine Nucleotide Exchange Factors; Histone Chaperones; Humans; Intracellular Signaling Peptides and Proteins; Kidney; Lysine; Mutation; Nuclear Proteins; Osteosarcoma; Phosphorylation; RNA, Small Interfering; Tumor Suppressor p53-Binding Protein 1; Ubiquitin; Ubiquitin-Protein Ligases; Ubiquitination; Ultraviolet Rays

2010
Studies of H3K4me3 demethylation by KDM5B/Jarid1B/PLU1 reveals strong substrate recognition in vitro and identifies 2,4-pyridine-dicarboxylic acid as an in vitro and in cell inhibitor.
    The FEBS journal, 2012, Volume: 279, Issue:11

    Topics: Amino Acid Sequence; Baculoviridae; Cell Line, Tumor; Chromatin; Enzyme Inhibitors; Histone Methyltransferases; Histone-Lysine N-Methyltransferase; Histones; Humans; Jumonji Domain-Containing Histone Demethylases; Kinetics; Lysine; Models, Molecular; Molecular Sequence Data; Nuclear Proteins; Osteosarcoma; Protein Isoforms; Pyridines; Recombinant Proteins; Repressor Proteins; Substrate Specificity; Transfection

2012
Antitumor effect of nutrient synergy on human osteosarcoma cells U-2OS, MNNG-HOS and Ewing's sarcoma SK-ES.1.
    Oncology reports, 2005, Volume: 13, Issue:2

    Topics: Arginine; Ascorbic Acid; Bone Neoplasms; Catechin; Cell Proliferation; Dose-Response Relationship, Drug; Humans; Lysine; Matrix Metalloproteinases; Neovascularization, Pathologic; Nutritional Physiological Phenomena; Osteosarcoma; Proline; Sarcoma, Ewing; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured; Vascular Endothelial Growth Factor A

2005
Inhibitory effect of a mixture containing ascorbic acid, lysine, proline and green tea extract on critical parameters in angiogenesis.
    Oncology reports, 2005, Volume: 14, Issue:4

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Ascorbic Acid; Cell Line, Tumor; Cell Proliferation; Chick Embryo; Chorioallantoic Membrane; Collagen; Dose-Response Relationship, Drug; Drug Combinations; Extracellular Matrix; Fibroblast Growth Factor 2; Formaldehyde; Humans; Immunohistochemistry; In Vitro Techniques; Laminin; Lysine; Matrix Metalloproteinases; Mice; Mice, Inbred C57BL; Mice, Nude; Neoplasm Invasiveness; Neoplasm Metastasis; Neoplasm Transplantation; Neovascularization, Pathologic; Osteosarcoma; Plant Extracts; Platelet-Derived Growth Factor; Proline; Proteoglycans; Tea; Tetrazolium Salts; Thiazoles; Time Factors; Transforming Growth Factor beta; Transforming Growth Factor beta1; Vascular Endothelial Growth Factor A

2005
Effect of ascorbic acid, lysine, proline, and green tea extract on human osteosarcoma cell line MNNG-HOS xenografts in nude mice: evaluation of tumor growth and immunohistochemistry.
    Medical oncology (Northwood, London, England), 2006, Volume: 23, Issue:3

    Topics: Animals; Antioxidants; Ascorbic Acid; Cell Line, Tumor; Humans; Immunohistochemistry; Lysine; Male; Mice; Mice, Nude; Neoplasm Transplantation; Osteosarcoma; Plant Extracts; Proline; Tea

2006
Functional characterization of TIP60 sumoylation in UV-irradiated DNA damage response.
    Oncogene, 2008, Feb-07, Volume: 27, Issue:7

    Topics: Bone Neoplasms; Cell Nucleus; Cells, Cultured; Cysteine Endopeptidases; DNA Damage; Electrophoresis, Polyacrylamide Gel; HeLa Cells; Histone Acetyltransferases; Humans; Kidney; Lysine; Lysine Acetyltransferase 5; Mass Spectrometry; Osteosarcoma; Protein Processing, Post-Translational; Proteomics; RNA, Small Interfering; Small Ubiquitin-Related Modifier Proteins; SUMO-1 Protein; Tumor Suppressor Protein p53; Ubiquitin-Conjugating Enzymes; Ultraviolet Rays

2008
PHD domain-mediated E3 ligase activity directs intramolecular sumoylation of an adjacent bromodomain required for gene silencing.
    Molecular cell, 2007, Dec-14, Volume: 28, Issue:5

    Topics: Adenosine Triphosphatases; Autoantigens; Bone Neoplasms; Cells, Cultured; Chromatin; DNA Helicases; DNA-Binding Proteins; Gene Expression Regulation; Gene Silencing; Histone Deacetylases; Histone-Lysine N-Methyltransferase; Humans; Kidney; Lysine; Mi-2 Nucleosome Remodeling and Deacetylase Complex; Osteosarcoma; Protein Methyltransferases; Protein Processing, Post-Translational; Repressor Proteins; RING Finger Domains; Saccharomyces cerevisiae; Small Ubiquitin-Related Modifier Proteins; Transcription, Genetic; Tripartite Motif-Containing Protein 28; Two-Hybrid System Techniques; Ubiquitin-Conjugating Enzymes; Ubiquitin-Protein Ligases

2007
Identification of a new site of sumoylation on Tel (ETV6) uncovers a PIAS-dependent mode of regulating Tel function.
    Molecular and cellular biology, 2008, Volume: 28, Issue:7

    Topics: Amino Acid Sequence; Animals; Biopolymers; Bone Neoplasms; Cell Line, Tumor; Conserved Sequence; ETS Translocation Variant 6 Protein; Humans; Lysine; Molecular Chaperones; Molecular Sequence Data; Osteosarcoma; Protein Inhibitors of Activated STAT; Protein Processing, Post-Translational; Proto-Oncogene Proteins c-ets; Repressor Proteins; Sequence Alignment; Sequence Homology, Amino Acid; Small Ubiquitin-Related Modifier Proteins; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; SUMO-1 Protein; Vertebrates

2008
Composition and posttranslational modification of individual collagen chains from osteosarcomas and osteofibrous dysplasias.
    Journal of cancer research and clinical oncology, 1995, Volume: 121, Issue:7

    Topics: Adolescent; Adult; Bone Neoplasms; Cell Division; Child; Collagen; Electrophoresis, Polyacrylamide Gel; Fibrous Dysplasia of Bone; Glycosylation; Humans; Hydroxylation; Hydroxylysine; Lysine; Osteosarcoma; Proline; Protein Processing, Post-Translational; Sodium Dodecyl Sulfate

1995
Cloning and sequencing of V genes from anti-osteosarcoma monoclonal antibodies TP-1 and TP-3: location of lysine residues and implications for radiolabeling.
    Nuclear medicine and biology, 1995, Volume: 22, Issue:6

    Topics: Amino Acid Sequence; Animals; Antibodies, Monoclonal; Base Sequence; Cloning, Molecular; Crystallography, X-Ray; DNA Primers; Dog Diseases; Dogs; Genes, Immunoglobulin; Humans; Immunoglobulin Heavy Chains; Immunoglobulin Light Chains; Immunoglobulin Variable Region; Lysine; Models, Molecular; Molecular Sequence Data; Osteosarcoma; Polymerase Chain Reaction; Protein Conformation; Radioimmunodetection

1995
Characterization of the activation function-2 domain of the human 1,25-dihydroxyvitamin D3 receptor.
    Molecular and cellular endocrinology, 1998, Apr-30, Volume: 139, Issue:1-2

    Topics: Animals; COS Cells; DNA; Humans; Ligands; Lysine; Osteocalcin; Osteosarcoma; Point Mutation; Rats; Receptors, Calcitriol; Recombinant Fusion Proteins; Sequence Alignment; Transcription Factor TFIIB; Transcription Factors; Transcriptional Activation; Transfection; Tumor Cells, Cultured

1998
Synthesis of fully active biotinylated analogues of parathyroid hormone and parathyroid hormone-related protein as tools for the characterization of parathyroid hormone receptors.
    Biochemistry, 1992, Apr-28, Volume: 31, Issue:16

    Topics: Affinity Labels; Amino Acid Sequence; Animals; Biotin; Cell Membrane; Chemical Phenomena; Chemistry, Physical; Cyclic AMP; Humans; Iodine Radioisotopes; Isotope Labeling; Kidney Cortex; Lysine; Molecular Sequence Data; Osteosarcoma; Parathyroid Hormone; Parathyroid Hormone-Related Protein; Proteins; Receptors, Cell Surface; Receptors, Parathyroid Hormone; Swine; Tumor Cells, Cultured

1992
Characterization of fully active biotinylated parathyroid hormone analogs. Application to fluorescence-activated cell sorting of parathyroid hormone receptor bearing cells.
    The Journal of biological chemistry, 1990, Jan-05, Volume: 265, Issue:1

    Topics: Animals; Avidin; Binding, Competitive; Biotin; Chromatography, High Pressure Liquid; Cyclic AMP; Flow Cytometry; Lysine; Osteosarcoma; Parathyroid Hormone; Peptide Fragments; Radioligand Assay; Rats; Receptors, Cell Surface; Receptors, Parathyroid Hormone; Teriparatide; Tumor Cells, Cultured

1990
Immunosuppressive effects of L-asparaginase.
    Cancer research, 1970, Volume: 30, Issue:6

    Topics: Adrenal Gland Neoplasms; Adult; Aged; Alanine; Antibody Formation; Antigens; Asparaginase; Asparagine; Breast Neoplasms; Carcinoma; Child, Preschool; Female; Glutamates; Hemocyanins; Humans; Hypersensitivity, Delayed; Immunoglobulins; Immunosuppressive Agents; Lectins; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Lymphocytes; Lysine; Male; Middle Aged; Neoplasms; Osteosarcoma; Tyrosine

1970