lysine and Neurodegenerative Diseases
lysine has been researched along with Neurodegenerative Diseases in 35 studies
Research
Studies (35)
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 0 (0.00) | 18.2507 |
2000's | 10 (28.57) | 29.6817 |
2010's | 18 (51.43) | 24.3611 |
2020's | 7 (20.00) | 2.80 |
Authors
Authors | Studies |
---|---|
Bao, L; Shi, Z; Xu, Y | 1 |
Amatori, S; Auber, LA; Cantatore, F; Casciaro, F; Fanelli, M; Giorgio, M; Perna, A; Persico, G; Rusin, M | 1 |
Cho, K; Hong, M; Jang, H; Jeon, YN; Jung, M; Kim, DH; Kim, MI; Kim, MS; Kim, NY; Lee, KH; Lee, SJ; Mun, YS; Na, DL; Pack, CG; Park, J; Shim, YL; Song, HL; Song, JA; Yoon, SY | 1 |
Chai, GS; Gong, J; Jia, DD; Ma, RK; Nie, YJ; Sun, HX; Wu, JJ; Xu, YL; Yu, HT; Zhai, XR; Zhang, YQ; Zhao, P; Zhu, J | 1 |
Blount, JR; Harris, AL; Libohova, K; Patel, NC; Sujkowski, A; Todi, SV; Tsou, WL | 1 |
Bialek, W; Tracz, M | 1 |
Benderoth, A; Farzadfard, A; Howard, KA; Mandrup, OA; Monge, P; Otzen, DE; Pedersen, AB; Pedersen, JN; Walther, R; Zelikin, AN | 1 |
Loskarn, S; Masliah, E; Regensburger, M; Rockenstein, E; Schreglmann, SR; Stoll, S; Winner, B; Xiang, W | 1 |
Kumar, D; Kumar, P | 1 |
Biggar, KK; Rowe, EM; Xing, V | 1 |
Michan, S | 1 |
Guedes-Dias, P; Oliveira, JM | 1 |
Arena, G; Bellia, F; Frasca, G; Grasso, G; Lanza, V; Milardi, D; Rizzarelli, E; Tabbì, G; Zito, V | 1 |
Dupré, N; Lu, JP; Rouleau, GA; Sliter, DA; Wojcikiewicz, RJ; Wright, FA | 1 |
de la Maza, MP; del Castillo, MD; Filip, R; Garay-Sevilla, ME; Gugliucci, A; Luevano-Contreras, C; Macías-Cervantes, MH; Markowicz Bastos, DH; Medrano, A; Menini, T; Portero-Otin, M; Rojas, A; Sampaio, GR; Uribarri, J; Wrobel, K | 1 |
Burchfield, JS; Li, Q; Wang, HY; Wang, RF | 1 |
Delgado-Andrade, C | 1 |
Bubacco, L; Plotegher, N | 1 |
Aksoy, A; Arboleda, VA; Bellen, HJ; Carmichael, J; Donti, T; Graham, BH; Haelterman, NA; Hunter, J; Jaiswal, M; Karaca, E; Lupski, JR; Muzny, DM; Nagarkar-Jaiswal, S; Nelson, SF; Nishi, E; Ohno, M; Putluri, N; Putluri, V; Sandoval, H; Shen, J; Sreekumar, A; Tos, T; Wangler, MF; Yamamoto, S; Yoon, WH | 1 |
Debry, JM | 1 |
Bajaj, N; Bedford, L; Cavey, JR; Layfield, R; Lowe, J; Mayer, RJ; Paine, S; Sheppard, PW; Thorpe, JR | 1 |
Ferezou, I; Geoffroy, H; Lainé, J; Perrenoud, Q; Rancillac, A; Rossier, J; Vitalis, T | 1 |
Chin, LS; Li, L; Olzmann, JA | 1 |
Basrur, V; Blount, JR; Conlon, KP; Elenitoba-Johnson, K; Pastore, A; Paulson, HL; Scaglione, KM; Todi, SV | 1 |
Boeve, BF; Dickson, DW; Dugger, BN; Fredrickson, P; Kaplan, J; Lin, SC; Spector, AR; Strongosky, A; Uitti, RJ; Wszolek, ZK | 1 |
Collaro, D; De Vivo, G; Gentile, V; Giuliano, A; Martin, A; Sedia, C; Serretiello, E | 1 |
Battaile, K; Cooper, AJ; Jeitner, TM | 1 |
Caputo, I; Esposito, C; Francese, S; Orrù, S; Ruoppolo, M | 1 |
Gorski, JA; Jones, KR; Tamowski, S; Zeiler, SR | 1 |
Burke, JR; Greenberg, CS; Lai, TS; Strittmatter, WJ; Tucker, T | 1 |
Dorval, V; Fraser, PE | 1 |
Bogenhagen, DF; Gravanis, I; Rogove, AD; Sheehan, JJ; Tsirka, SE; Wu, YP; Zhou, C | 1 |
Chin, LS; Olzmann, JA | 1 |
Cooper, AJ; Danson, JW; Trawick, ML | 1 |
Dantuma, NP; de Vrij, FM; Fischer, DF; Hol, EM; Lindsten, K; Masucci, MG; van Leeuwen, FW; Verhoef, LG | 1 |
Reviews
12 review(s) available for lysine and Neurodegenerative Diseases
Article | Year |
---|---|
An Expanding Repertoire of Protein Acylations.
Topics: Acetylation; Acylation; Histones; Humans; Lysine; Neurodegenerative Diseases; Protein Processing, Post-Translational | 2022 |
Beyond K48 and K63: non-canonical protein ubiquitination.
Topics: Animals; DNA Damage; Humans; Immunity, Innate; Lysine; Neurodegenerative Diseases; Proteins; Ubiquitination | 2021 |
Lysine methylation: Implications in neurodegenerative disease.
Topics: Animals; Epigenesis, Genetic; Histone-Lysine N-Methyltransferase; Histones; Humans; Lysine; Methylation; Neurodegenerative Diseases; Protein Processing, Post-Translational; Signal Transduction | 2019 |
Acetylome regulation by sirtuins in the brain: from normal physiology to aging and pathology.
Topics: Acetylation; Aging; Animals; Autophagy; Brain; Brain Neoplasms; Cellular Senescence; Circadian Rhythm; DNA Damage; Emotions; Humans; Lysine; Neurodegenerative Diseases; Neurogenesis; NF-kappa B; Oxidative Stress; Proteome; Sirtuins | 2013 |
Lysine deacetylases and mitochondrial dynamics in neurodegeneration.
Topics: Animals; Histone Deacetylases; Humans; Lysine; Mitochondrial Dynamics; Neurodegenerative Diseases | 2013 |
Dietary advanced glycation end products and their role in health and disease.
Topics: Agriculture; Chronic Disease; Cooking; Diet; Exercise; Food; Food Handling; Glycation End Products, Advanced; Health Status; Hot Temperature; Humans; Inflammation; Lysine; Mexico; Neurodegenerative Diseases; Oxidative Stress; Receptor for Advanced Glycation End Products; Solubility | 2015 |
JMJD3 as an epigenetic regulator in development and disease.
Topics: Animals; Chromatin; Enhancer of Zeste Homolog 2 Protein; Epigenesis, Genetic; Gene Expression Regulation, Developmental; Germ Layers; Histone Demethylases; Histones; Humans; Immunity, Innate; Jumonji Domain-Containing Histone Demethylases; Lysine; Mice; Neoplasms; Neurodegenerative Diseases; Nuclear Proteins; Polycomb Repressive Complex 2 | 2015 |
Carboxymethyl-lysine: thirty years of investigation in the field of AGE formation.
Topics: Biological Availability; Bone Diseases; Diet; Food; Food Contamination; Food Handling; Glycation End Products, Advanced; Hot Temperature; Humans; Lysine; Maillard Reaction; Neoplasms; Neurodegenerative Diseases; Oxidative Stress | 2016 |
Lysines, Achilles' heel in alpha-synuclein conversion to a deadly neuronal endotoxin.
Topics: 3,4-Dihydroxyphenylacetic Acid; Aldehydes; alpha-Synuclein; Brain; Dopamine; Humans; Lysine; Metabolism; Neurodegenerative Diseases; Neurons | 2016 |
Parkin-mediated ubiquitin signalling in aggresome formation and autophagy.
Topics: Autophagy; Humans; Inclusion Bodies; Lysine; Neurodegenerative Diseases; Parkinson Disease; Polyubiquitin; Protein Conformation; Protein Folding; Signal Transduction; Ubiquitin-Protein Ligases; Ubiquitination | 2010 |
Possible involvement of transglutaminase-catalyzed reactions in the physiopathology of neurodegenerative diseases.
Topics: Animals; Cell Death; Glutamine; Humans; Lysine; Molecular Targeted Therapy; Neurodegenerative Diseases; Peptides; Protein Processing, Post-Translational; Transglutaminases | 2013 |
γ-Glutamylamines and neurodegenerative diseases.
Topics: Amines; Animals; Dipeptides; gamma-Glutamylcyclotransferase; Glutamine; Humans; Lysine; Neurodegenerative Diseases; Protein Processing, Post-Translational; Transglutaminases | 2013 |
Other Studies
23 other study(ies) available for lysine and Neurodegenerative Diseases
Article | Year |
---|---|
Histone H3 Lysine 4 and 27 Trimethylation Landscape of Human Alzheimer's Disease.
Topics: Alzheimer Disease; Epigenesis, Genetic; Female; Histones; Humans; Lysine; Male; Methylation; Neurodegenerative Diseases; Promoter Regions, Genetic | 2022 |
Monoclonal antibody Y01 prevents tauopathy progression induced by lysine 280-acetylated tau in cell and mouse models.
Topics: Alzheimer Disease; Animals; Antibodies, Monoclonal; Brain; Disease Models, Animal; Lysine; Mice; Neurodegenerative Diseases; tau Proteins; Tauopathies | 2023 |
Danggui Buxue decoction ameliorates mitochondrial biogenesis and cognitive deficits through upregulating histone H4 lysine 12 acetylation in APP/PS1 mice.
Topics: Acetylation; Alzheimer Disease; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Amyloid Precursor Protein Secretases; Animals; Aspartic Acid Endopeptidases; Cognition; Disease Models, Animal; Histones; Lysine; Mice; Mice, Transgenic; Neurodegenerative Diseases; Organelle Biogenesis; Protein Processing, Post-Translational | 2023 |
Lysine 117 on ataxin-3 modulates toxicity in Drosophila models of Spinocerebellar Ataxia Type 3.
Topics: Animals; Ataxin-3; Drosophila; Humans; Lysine; Machado-Joseph Disease; Neurodegenerative Diseases; Ubiquitin | 2023 |
Per-glycosylation of the Surface-Accessible Lysines: One-Pot Aqueous Route to Stabilized Proteins with Native Activity.
Topics: Glycosylation; Lysine; Neurodegenerative Diseases | 2021 |
Oligomer-prone E57K-mutant alpha-synuclein exacerbates integration deficit of adult hippocampal newborn neurons in transgenic mice.
Topics: alpha-Synuclein; Animals; Bromodeoxyuridine; Caspase 3; Cell Proliferation; Disease Models, Animal; Doublecortin Domain Proteins; Gene Expression Regulation; Glutamic Acid; Hippocampus; Lysine; Mice; Mice, Inbred C57BL; Mice, Transgenic; Microtubule-Associated Proteins; Mutation; Neurodegenerative Diseases; Neurogenesis; Neurons; Neuropeptides; Phosphopyruvate Hydratase; SOXB1 Transcription Factors | 2018 |
An In-Silico Investigation of Key Lysine Residues and Their Selection for Clearing off Aβ and Holo-AβPP Through Ubiquitination.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Amyloid Precursor Protein Secretases; Apolipoproteins E; Computer Simulation; Databases, Protein; Humans; Lysine; Neurodegenerative Diseases; Neurons; Static Electricity; tau Proteins; Ubiquitin; Ubiquitination | 2019 |
Inorganic stressors of ubiquitin.
Topics: Copper; Homeostasis; Hydrogen-Ion Concentration; Lysine; Models, Molecular; Neurodegenerative Diseases; Ubiquitin; Ubiquitin-Conjugating Enzymes; Ubiquitination; Zinc | 2013 |
A Point Mutation in the Ubiquitin Ligase RNF170 That Causes Autosomal Dominant Sensory Ataxia Destabilizes the Protein and Impairs Inositol 1,4,5-Trisphosphate Receptor-mediated Ca2+ Signaling.
Topics: Animals; Arginine; Ataxia; Calcium; Calcium Signaling; Cell Line; Cell Membrane; Endoplasmic Reticulum; Exons; HeLa Cells; Humans; Inositol 1,4,5-Trisphosphate Receptors; Lysine; Mice; Mutation; Neurodegenerative Diseases; Point Mutation; Proteasome Endopeptidase Complex; Signal Transduction; Ubiquitin; Ubiquitin-Protein Ligases | 2015 |
Loss of Nardilysin, a Mitochondrial Co-chaperone for α-Ketoglutarate Dehydrogenase, Promotes mTORC1 Activation and Neurodegeneration.
Topics: Animals; Autophagy; Drosophila; Drosophila melanogaster; Drosophila Proteins; Ketoglutarate Dehydrogenase Complex; Ketoglutaric Acids; Lysine; Mechanistic Target of Rapamycin Complex 1; Metalloendopeptidases; Mitochondria; Molecular Chaperones; Multiprotein Complexes; Neurodegenerative Diseases; TOR Serine-Threonine Kinases | 2017 |
[SUMO, small but strong].
Topics: Animals; Humans; Lysine; Neurodegenerative Diseases; Protein Processing, Post-Translational; Proteins; Saccharomyces cerevisiae Proteins; Small Ubiquitin-Related Modifier Proteins; Substrate Specificity; Ubiquitin; Ubiquitination | 2008 |
Immunoreactivity to Lys63-linked polyubiquitin is a feature of neurodegeneration.
Topics: Alzheimer Disease; Animals; Brain; Humans; Huntington Disease; Immunohistochemistry; Lewy Bodies; Lysine; Mice; Neurodegenerative Diseases; Neurons; Parkinson Disease; Polyubiquitin; Proteasome Endopeptidase Complex | 2009 |
Degenerative abnormalities in transgenic neocortical neuropeptide Y interneurons expressing tau-green fluorescent protein.
Topics: Animals; Axons; Dendrites; Fluorescent Antibody Technique; In Vitro Techniques; Interneurons; Luminescent Proteins; Lysine; Lysosomal Membrane Proteins; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Microscopy, Immunoelectron; Neurodegenerative Diseases; Neuropeptide Y; Patch-Clamp Techniques; Reverse Transcriptase Polymerase Chain Reaction; Somatosensory Cortex; tau Proteins | 2010 |
Activity and cellular functions of the deubiquitinating enzyme and polyglutamine disease protein ataxin-3 are regulated by ubiquitination at lysine 117.
Topics: Animals; Ataxin-3; Binding Sites; Catalysis; Fibroblasts; Gene Expression Regulation; Humans; Lysine; Machado-Joseph Disease; Mice; Nerve Tissue Proteins; Neurodegenerative Diseases; Nuclear Proteins; Protein Conformation; Repressor Proteins; Structure-Activity Relationship; Transfection; Ubiquitin | 2010 |
Anatomy of disturbed sleep in pallido-ponto-nigral degeneration.
Topics: Actigraphy; Adult; Asparagine; Female; Genetic Testing; Globus Pallidus; Humans; Lysine; Male; Middle Aged; Mutation; Neurodegenerative Diseases; Neurofibrillary Tangles; Polysomnography; Pons; Severity of Illness Index; Sleep Wake Disorders; Substantia Nigra; tau Proteins; Tyrosine 3-Monooxygenase; Young Adult | 2011 |
Structural characterization of transglutaminase-catalyzed cross-linking between glyceraldehyde 3-phosphate dehydrogenase and polyglutamine repeats.
Topics: Animals; Catalysis; Glyceraldehyde-3-Phosphate Dehydrogenases; GTP-Binding Proteins; Guinea Pigs; Liver; Lysine; Neurodegenerative Diseases; Peptides; Protein Glutamine gamma Glutamyltransferase 2; Rabbits; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Substrate Specificity; Transglutaminases; Trinucleotide Repeats | 2003 |
Brain-derived neurotrophic factor is required for the maintenance of cortical dendrites.
Topics: Age Factors; Animals; Behavior, Animal; Brain-Derived Neurotrophic Factor; Cell Count; Cell Size; Cell Survival; Cerebral Cortex; Dendrites; Female; Gene Expression Regulation, Developmental; Gene Targeting; Lysine; Male; Mice; Mice, Mutant Strains; Neurodegenerative Diseases; Neurons; Organ Specificity; Prosencephalon; Pyramidal Cells | 2003 |
Effect of tissue transglutaminase on the solubility of proteins containing expanded polyglutamine repeats.
Topics: Biotinylation; Calcium; Catalysis; Electrophoresis, Polyacrylamide Gel; GTP-Binding Proteins; Histamine; Immunoblotting; Lysine; Macromolecular Substances; Molecular Weight; Neurodegenerative Diseases; Peptides; Protein Glutamine gamma Glutamyltransferase 2; Putrescine; Recombinant Fusion Proteins; Repetitive Sequences, Amino Acid; Solubility; Thioredoxins; Transglutaminases | 2004 |
Small ubiquitin-like modifier (SUMO) modification of natively unfolded proteins tau and alpha-synuclein.
Topics: alpha-Synuclein; Blotting, Western; Cell Line; Epitopes; Humans; Lysine; Microtubules; Neurodegenerative Diseases; Phosphorylation; Plasmids; Proteasome Endopeptidase Complex; Protein Binding; Protein Denaturation; Protein Folding; Protein Structure, Tertiary; Small Ubiquitin-Related Modifier Proteins; SUMO-1 Protein; tau Proteins; Transfection; Ubiquitin; Ubiquitins | 2006 |
Proteolytic activation of monocyte chemoattractant protein-1 by plasmin underlies excitotoxic neurodegeneration in mice.
Topics: Analysis of Variance; Animals; Antigens, Differentiation; Blotting, Western; Cell Line; Cell Movement; Chemokine CCL2; Drug Interactions; Enzyme-Linked Immunosorbent Assay; Fibrinolysin; Fibrinolytic Agents; Gene Expression Regulation; Green Fluorescent Proteins; Hippocampus; In Situ Nick-End Labeling; Kainic Acid; Lysine; Mice; Mice, Inbred C57BL; Mice, Knockout; Microglia; Neurodegenerative Diseases; Time Factors; Transfection | 2007 |
Parkin-mediated K63-linked polyubiquitination: a signal for targeting misfolded proteins to the aggresome-autophagy pathway.
Topics: Animals; Autophagy; Humans; Inclusion Bodies; Lysine; Models, Biological; Neurodegenerative Diseases; Polyubiquitin; Protein Folding; Ubiquitin-Protein Ligases; Ubiquitination | 2008 |
Spectrophotometric assays for L-lysine alpha-oxidase and gamma-glutamylamine cyclotransferase.
Topics: Amino Acid Oxidoreductases; Aminocaproates; Animals; Carbazoles; Carcinogens; Cattle; gamma-Glutamylcyclotransferase; gamma-Glutamyltransferase; Kidney; Liver; Lysine; Male; Neurodegenerative Diseases; Rats; Rats, Inbred F344; Semicarbazides; Spectrophotometry | 2002 |
Mutant ubiquitin found in neurodegenerative disorders is a ubiquitin fusion degradation substrate that blocks proteasomal degradation.
Topics: Cell Cycle; Cysteine Endopeptidases; Green Fluorescent Proteins; HeLa Cells; Humans; Luminescent Proteins; Lysine; Multienzyme Complexes; Mutation; Neurodegenerative Diseases; Neurons; Proteasome Endopeptidase Complex; Proteins; Substrate Specificity; Tumor Cells, Cultured; Ubiquitin | 2002 |