Compounds > lysine
Page last updated: 2024-08-17

lysine and Neoplasm Metastasis

lysine has been researched along with Neoplasm Metastasis in 64 studies

Research

Studies (64)

TimeframeStudies, this research(%)All Research%
pre-19905 (7.81)18.7374
1990's0 (0.00)18.2507
2000's16 (25.00)29.6817
2010's35 (54.69)24.3611
2020's8 (12.50)2.80

Authors

AuthorsStudies
Cao, J; Cao, JM; Feng, YL; Gao, LJ; Hou, JY; Shen, J; Shi, JY; Wang, DP; Yan, Z; Zhang, FP; Zhou, L1
Feng, T; Gu, R; Guo, Y; Li, K; Li, Q; Li, S; Lin, P; Ou, D; Yuan, H; Zhang, J; Zhao, G1
Diao, H; Hao, N; Koropatnick, J; Liu, Q; Maleki Vareki, S; Min, J; Min, W; Raphael, J; Sang, Y; Wang, Z; Xiong, J; Xu, D; Zhang, Y; Zheng, X1
Chen, Y; He, QM; He, SW; Hong, XH; Lei, Y; Li, JY; Li, YQ; Liang, YL; Liu, N; Luo, WJ; Ma, J; Tang, LL; Wang, YQ; Yang, XJ; Zhang, PP; Zhao, Y1
Huang, T; Jiang, G; Lyu, L; Xiang, W; Yuan, J; Zhang, C; Zheng, F1
Gao, J; Lin, M; Liu, Y; Wang, G; Wu, Y; Xu, B; Yu, H1
Cao, D; Ding, H; Hou, J; Huang, B; Lin, C; Liu, J; Liu, L; Liu, X; Liu, Y; Lu, J; Wang, G; Zhang, N; Zhang, X; Zhang, Y1
Gu, Y; Guo, G; Li, L; Wang, F; Wang, N; Wang, X; Xiong, Y; Zhu, M1
Kalinovsky, T; Niedzwiecki, A; Rath, M; Roomi, MW1
Chen, W; Han, C; Kwon, H; Lu, L; Song, K; Wu, T; Zhang, J1
Cornelis, FH; Durack, JC; Morris, MJ; Scher, HI; Solomon, SB1
Broos, WAM; Knol, RJJ; Kocken, M; van der Zant, FM; Wondergem, M1
Dai, B; Guan, F; Hu, Z; Huang, H; Mao, B; Su, H; Xiao, Z; Zhu, G1
Shao, B; Tian, L; Yan, Y; Zhou, W; Zhu, B1
Knol, RJJ; van der Zant, FM; Vlottes, PW; Wondergem, M1
Hayakawa, Y; Iwakami, Y; Watanabe, K; Yokoyama, S1
Ding, C; Ding, W; Du, J; Feng, XH; Fu, P; Guan, KL; Jin, J; Jin, K; Li, F; Shao, L; van Dam, H; Wang, A; Wang, S; Wei, B; Yang, B; Zhang, L; Zhang, Z; Zheng, M1
Li, L; Li, R; Wang, Y1
Chen, Z; Cheng, G; Du, P; Hu, K; Shen, X; Xu, L; Zhuang, Z1
Broos, WAM; Knol, RJJ; Srbljin, S; van der Zant, FM; Wondergem, M1
Bosco, A; Dhiantravan, N; Hovey, E; Wegner, EA1
Evers, BM; Huang, C; Kutys, ML; Li, X; Morris, AJ; Rychahou, P; Sunkara, M; Wu, Z; Zhou, Q; Zhu, H1
Bailey, KM; Balagurunathan, Y; Cornnell, HH; Gillies, RJ; Hashim, AI; Ribeiro, MC; Wojtkowiak, JW1
Kang, C; Kim, MY; Lee, J; Song, JJ1
Chen, J; Chowdhury, F; Doğanay, S; Ha, T; Hong, Y; Huang, B; Jia, H; Jia, Q; Li, Y; Lin, LJ; Poh, YC; Seong, J; Singh, R; Tajik, A; Tan, Y; Wang, L; Wang, N; Wang, Y; Wei, F; Wu, DC; Yi, H; Zhang, S; Zhang, Y1
Fukami, K; Matsui, T; Yamagishi, S1
Castle, EP; Champion, MD; Dykema, K; Ho, TH; Hoang, A; Hung, MC; Jonasch, E; Joseph, RW; Monzon, FA; Nunez-Nateras, R; Park, IY; Parker, AS; Qiao, W; Tamboli, P; Tannir, NM; Teh, BT; Tong, P; Walker, CL; Wang, J; Yan, H; Zhao, H1
Allaf, ME; Cho, SY; Gorin, MA; Hammers, HJ; Hawasli, H; Pomper, MG; Rowe, SP; Som Javadi, M; Szabo, Z1
Allaf, ME; Gorin, MA; Hammers, HJ; Javadi, MS; Pomper, MG; Rowe, SP1
Dong, H; Gao, Y; Jia, L; Li, T; Lu, Y; Ma, J; Shao, J; Tu, X; Wan, L; Wang, J; Xie, F; Xie, J; Xu, B; Xu, H; Zhang, T; Zhu, Y1
Avaritt, NL; Byrum, SD; Davis, L; Mackintosh, SG; Mahmoud, F; Orr, LM; Reynolds, M; Sengupta, D; Shalin, SC; Shields, B; Tackett, AJ1
Hou, L; Li, M; Li, Q; Yu, Y; Zhang, D1
Gius, D; O'Brien, J; Santa-Maria, CA; Zhu, Y; Zou, X1
Fujiwara, N; Imoto, S; Inazawa, J; Kawano, T; Kozaki, KI; Miyano, S; Morishita, M; Muramatsu, T; Tsuda, H; Yamaguchi, R1
Jiang, K; Luo, J; Mustonen, H; Puolakkainen, P; Shen, Z; Wang, B; Wang, S; Ye, Y; Zhang, H; Zhu, J1
Cai, Q; Casero, RA; Chen, H; Dou, Y; Jin, L; Jin, Y; Li, X; Liu, Y; Lu, J; Luo, H; Qiu, Y; Reisman, D; Seto, E; Shenoy, AK; Tang, M; Wu, L1
Clevenger, CV; Craig, JM; Feeney, YB; Fiorillo, AA; Harrell, JC; Medler, TR1
Giaccia, AJ1
Blum, G; Bothwell, IR; Kapilashrami, K; Linscott, JA; Luo, M; Senevirathne, C; Wang, Z1
Bastian, BC; Bauer, J; Lutzky, J1
Barraclough, R; Fernig, DG; Ismail, TM; Rudland, PS; Terry, CJ; Wang, G1
Chen, BH; Hsu, HS; Jin, JS; Lee, SC; Sun, GH; Tung, HJ; Tzao, C; Yu, CP1
Ateeq, B; Brenner, JC; Cao, Q; Cao, X; Chinnaiyan, AM; Han, B; Jing, X; Kim, JH; Kumar-Sinha, C; Laxman, B; Lonigro, RJ; Maher, CA; Mani, RS; Palanisamy, N; Ramnarayanan, K; Shankar, S; Tan, P; Varambally, S; Wang, X; Yu, J1
Chen, N; Chen, X; Deng, X; Hao, Y; He, F; Jia, W; Jiang, Y; Ma, J; Qian, X; Sun, W; Wei, H; Xing, B; Zhu, Y1
Igarashi, Y; Miyanaga, S; Onaka, H; Saiki, I; Sakurai, H1
Andries, M; Bollen, M; Derua, R; Jansen, S; Waelkens, E1
Akiyama, SK; Olden, K; Ray, DM; Roberts, JD; Rogers, BA; Sunman, JA1
Cai, MY; Guan, XY; Kong, LL; Kung, HF; Rao, HL; Tong, ZT; Wen, ZZ; Xie, D; Zeng, YX; Zhu, W1
Huang, C; Li, J; Liu, J; Wu, XR; Yu, J; Yu, Y; Zhang, D1
Desaire, H; Finney, J; Go, EP; Lantz, M; Moon, H; Mure, M; Rebecchi, K; Xu, L1
Kaetzel, DM; Ma, D; McCorkle, JR1
Abulrob, A; Alakhov, V; Ball, M; Ekiel, I; Moreno, MJ; Onichtchenko, A; Pietrzynski, G; Semov, A; Stanimirovic, D1
Amidon, GL; Landowski, CP; Song, X; Vig, BS1
Ivanov, V; Kalinovsky, T; Niedzwiecki, A; Rath, M; Roomi, MW; Roomi, N1
Degani, H; Eshhar, Z; Kalchenko, V; Makovitzki, A; Papo, N; Seger, D; Shai, Y1
Chen, CD; Han, G; Lin, H; Xiang, Y; Xu, L; Zhu, Z1
Akhurst, RJ; Derynck, R; Kang, JS; Saunier, EF1
Gebbink, MF; Reijerkerk, A; Voest, EE1
Lilja, H; Lindgren, S; Nurmikko, P; Pettersson, K; Piironen, T; Väisänen, V1
Bojan, O; Kiricuta, I1
Laki, K1
Amatruda, TT; Upton, GV1
Laki, K; Yancey, ST1
Bojan, O; Mustea, I; Preda, N1

Reviews

4 review(s) available for lysine and Neoplasm Metastasis

ArticleYear
Epigenetics: an emerging player in gastric cancer.
    World journal of gastroenterology, 2014, Jun-07, Volume: 20, Issue:21

    Topics: Chromatin; Disease Progression; DNA Methylation; Epigenesis, Genetic; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Histones; Humans; Lysine; MicroRNAs; Neoplasm Metastasis; Nucleosomes; RNA, Long Noncoding; Stomach Neoplasms

2014
Role of receptor for advanced glycation end products (RAGE) and its ligands in cancer risk.
    Rejuvenation research, 2015, Volume: 18, Issue:1

    Topics: Animals; Apoptosis; Cell Line, Tumor; Cell Proliferation; Diabetes Mellitus; Disease Progression; Humans; Inflammation; Ligands; Lysine; Melanoma; Mice; Neoplasm Metastasis; Neoplasms; Oxidative Stress; Receptor for Advanced Glycation End Products; Risk Factors; Treatment Outcome

2015
Manganese Superoxide Dismutase Acetylation and Dysregulation, Due to Loss of SIRT3 Activity, Promote a Luminal B-Like Breast Carcinogenic-Permissive Phenotype.
    Antioxidants & redox signaling, 2016, 08-20, Volume: 25, Issue:6

    Topics: Acetylation; Aging; Biomarkers, Tumor; Breast Neoplasms; Enzyme Activation; Female; Gene Expression Regulation, Neoplastic; Humans; Incidence; Longevity; Lysine; Molecular Targeted Therapy; Neoplasm Metastasis; Phenotype; Recurrence; Sirtuin 3; Superoxide Dismutase

2016
No grip, no growth: the conceptual basis of excessive proteolysis in the treatment of cancer.
    European journal of cancer (Oxford, England : 1990), 2000, Volume: 36, Issue:13 Spec No

    Topics: Angiogenesis Inhibitors; Angiostatins; Antineoplastic Agents; Carboxypeptidase B2; Carboxypeptidases; Collagen; Endostatins; Humans; Lysine; Neoplasm Metastasis; Neoplasm Proteins; Neoplasms; Neovascularization, Pathologic; Peptide Fragments; Plasminogen; Plasminogen Activators; Thrombolytic Therapy; Urokinase-Type Plasminogen Activator

2000

Trials

2 trial(s) available for lysine and Neoplasm Metastasis

ArticleYear
Effects of Fasting on
    Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 2018, Volume: 59, Issue:7

    Topics: Aged; Aged, 80 and over; Biological Transport; Fasting; Humans; Lysine; Male; Middle Aged; Neoplasm Metastasis; Positron Emission Tomography Computed Tomography; Prostatic Neoplasms; Urea

2018
Imaging of metastatic clear cell renal cell carcinoma with PSMA-targeted ¹⁸F-DCFPyL PET/CT.
    Annals of nuclear medicine, 2015, Volume: 29, Issue:10

    Topics: Aged; Antigens, Surface; Carcinoma, Renal Cell; Glutamate Carboxypeptidase II; Humans; Kidney Neoplasms; Lysine; Male; Middle Aged; Multimodal Imaging; Neoplasm Metastasis; Positron-Emission Tomography; Tomography, X-Ray Computed; Urea

2015

Other Studies

58 other study(ies) available for lysine and Neoplasm Metastasis

ArticleYear
Upregulation of α enolase (ENO1) crotonylation in colorectal cancer and its promoting effect on cancer cell metastasis.
    Biochemical and biophysical research communications, 2021, 11-12, Volume: 578

    Topics: Biomarkers, Tumor; Cell Line, Tumor; Cell Movement; Cell Proliferation; Colorectal Neoplasms; CREB-Binding Protein; DNA-Binding Proteins; Humans; Lysine; Mass Spectrometry; Neoplasm Metastasis; Phosphopyruvate Hydratase; Protein Processing, Post-Translational; Sirtuin 2; Tumor Suppressor Proteins; Up-Regulation

2021
Loss of TRIM31 promotes breast cancer progression through regulating K48- and K63-linked ubiquitination of p53.
    Cell death & disease, 2021, 10-14, Volume: 12, Issue:10

    Topics: Animals; Breast Neoplasms; Carcinogenesis; Cell Line, Tumor; Cell Movement; Cell Proliferation; Disease Progression; Down-Regulation; Female; Gene Expression Regulation, Neoplastic; Humans; Lysine; Mice, Inbred C57BL; Mice, Nude; Middle Aged; Neoplasm Invasiveness; Neoplasm Metastasis; Protein Binding; Protein Domains; Protein Stability; Proto-Oncogene Proteins c-mdm2; RNA, Messenger; Treatment Outcome; Tripartite Motif Proteins; Tumor Suppressor Protein p53; Ubiquitin-Protein Ligases; Ubiquitination

2021
TdIF1-LSD1 Axis Regulates Epithelial-Mesenchymal Transition and Metastasis via Histone Demethylation of E-Cadherin Promoter in Lung Cancer.
    International journal of molecular sciences, 2021, 12-27, Volume: 23, Issue:1

    Topics: Animals; Cadherins; Carcinogenesis; Cell Line, Tumor; Cell Movement; Demethylation; DNA-Binding Proteins; Down-Regulation; Epithelial-Mesenchymal Transition; Gene Expression Regulation, Neoplastic; Gene Knockdown Techniques; Histone Demethylases; Histones; Lung Neoplasms; Lysine; Methylation; Mice, Inbred BALB C; Mice, Nude; Neoplasm Invasiveness; Neoplasm Metastasis; Promoter Regions, Genetic; Protein Binding; Transcription Factors

2021
Hypermethylation of
    Cells, 2020, 02-27, Volume: 9, Issue:3

    Topics: Animals; Cell Line, Tumor; Cell Movement; Cortactin; DNA Methylation; Down-Regulation; Female; Gene Expression Regulation, Neoplastic; HEK293 Cells; Humans; Lysine; Mice, Inbred BALB C; Mice, Nude; Nasopharyngeal Carcinoma; Neoplasm Invasiveness; Neoplasm Metastasis; Promoter Regions, Genetic; Protein Binding; Proteolysis; Ubiquitin Thiolesterase; Ubiquitination

2020
The long non-coding RNA SNHG1 promotes bladder cancer progression by interacting with miR-143-3p and EZH2.
    Journal of cellular and molecular medicine, 2020, Volume: 24, Issue:20

    Topics: Animals; Antigens, CD; Base Sequence; Cadherins; Carcinogenesis; Cell Line, Tumor; Cell Movement; Cell Nucleus; Cell Proliferation; Cytoplasm; Disease Progression; Enhancer of Zeste Homolog 2 Protein; Epigenesis, Genetic; Female; Gene Expression Regulation, Neoplastic; Gene Silencing; Hexokinase; Histones; Humans; Lysine; Male; Methylation; Mice, Inbred BALB C; Mice, Nude; MicroRNAs; Middle Aged; Models, Biological; Neoplasm Invasiveness; Neoplasm Metastasis; RNA, Long Noncoding; Transcription, Genetic; Up-Regulation; Urinary Bladder Neoplasms

2020
Comparison of 18F-DCFPyL and 18F-FDG PET/computed tomography for the restaging of clear cell renal cell carcinoma: preliminary results of 15 patients.
    Nuclear medicine communications, 2020, Volume: 41, Issue:12

    Topics: Aged; Carcinoma, Renal Cell; Female; Fluorodeoxyglucose F18; Humans; Kidney Neoplasms; Lysine; Male; Middle Aged; Neoplasm Metastasis; Neoplasm Staging; Positron Emission Tomography Computed Tomography; Recurrence; Retrospective Studies; Urea

2020
Arginine and lysine methylation of MRPS23 promotes breast cancer metastasis through regulating OXPHOS.
    Oncogene, 2021, Volume: 40, Issue:20

    Topics: Arginine; Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; Female; Humans; Lysine; Methylation; Mitochondria; Neoplasm Metastasis; Organoids; Oxidative Phosphorylation; Protein Methyltransferases; Protein Processing, Post-Translational; Protein-Arginine N-Methyltransferases

2021
Aberrant super-enhancer-driven oncogene ENC1 promotes the radio-resistance of breast carcinoma.
    Cell death & disease, 2021, 08-06, Volume: 12, Issue:8

    Topics: Acetylation; Animals; Breast Neoplasms; Cell Line, Tumor; Enhancer Elements, Genetic; Female; Gene Expression Regulation, Neoplastic; Histones; Humans; Intracellular Signaling Peptides and Proteins; Lysine; Mice, Inbred BALB C; Mice, Nude; Microfilament Proteins; Neoplasm Metastasis; Neuropeptides; Nuclear Proteins; Oncogenes; Prognosis; Protein Serine-Threonine Kinases; Radiation Tolerance; RNA, Small Interfering; Transcription Factor 4; Transcriptional Activation; Transcriptional Coactivator with PDZ-Binding Motif Proteins; YAP-Signaling Proteins

2021
A Specific Mixture of Nutrients Suppresses Ovarian Cancer A-2780 Tumor Incidence, Growth, and Metastasis to Lungs.
    Nutrients, 2017, Mar-18, Volume: 9, Issue:3

    Topics: Animals; Antioxidants; Ascorbic Acid; Cell Line, Tumor; Cell Proliferation; Dietary Supplements; Dose-Response Relationship, Drug; Female; Humans; Lung Neoplasms; Lysine; Matrix Metalloproteinase 9; Mice; Mice, Nude; Micronutrients; Neoplasm Metastasis; Ovarian Neoplasms; Plant Extracts; Proline; Quercetin; Tea; Xenograft Model Antitumor Assays

2017
Epigenetic Silencing of miRNA-34a in Human Cholangiocarcinoma via EZH2 and DNA Methylation: Impact on Regulation of Notch Pathway.
    The American journal of pathology, 2017, Volume: 187, Issue:10

    Topics: Animals; Base Sequence; Bile Duct Neoplasms; Cell Line, Tumor; Cell Proliferation; Cholangiocarcinoma; CpG Islands; DNA Methylation; Enhancer of Zeste Homolog 2 Protein; Epigenesis, Genetic; Gene Expression Regulation, Neoplastic; Gene Silencing; Histones; Humans; Indoles; Lysine; Male; Mice, Inbred NOD; MicroRNAs; Neoplasm Metastasis; Pyridones; Receptors, Notch; Signal Transduction; Tumor Stem Cell Assay

2017
Effective Prostate-Specific Membrane Antigen-Based 18F-DCFPyL-Guided Cryoablation of a Single Positive Site in a Patient Believed to Be More Metastatic on 11C-Choline PET/CT.
    Clinical nuclear medicine, 2017, Volume: 42, Issue:12

    Topics: Aged; Antigens, Surface; Carbon Radioisotopes; Choline; Cryosurgery; Glutamate Carboxypeptidase II; Humans; Lysine; Male; Neoplasm Metastasis; Positron Emission Tomography Computed Tomography; Prostatic Neoplasms; Surgery, Computer-Assisted; Urea

2017
Metastasized 18F-DCFPyL-Negative Prostatic Adenocarcinoma Without Neuroendocrine Differentiation.
    Clinical nuclear medicine, 2018, Volume: 43, Issue:2

    Topics: Adenocarcinoma; Aged; Humans; Lysine; Male; Neoplasm Metastasis; Neurosecretory Systems; Positron Emission Tomography Computed Tomography; Prostatic Neoplasms; Urea

2018
Histone demethylase KDM5A inhibits glioma cells migration and invasion by down regulating ZEB1.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2018, Volume: 99

    Topics: Biocatalysis; Biomarkers, Tumor; Cell Line, Tumor; Cell Movement; Down-Regulation; Epithelial-Mesenchymal Transition; Gene Expression Regulation, Neoplastic; Gene Knockdown Techniques; Glioma; Histones; Humans; Lysine; Methylation; Neoplasm Invasiveness; Neoplasm Metastasis; Promoter Regions, Genetic; Retinoblastoma-Binding Protein 2; Zinc Finger E-box-Binding Homeobox 1

2018
Downregulation of SIRT6 is associated with poor prognosis in patients with non-small cell lung cancer.
    The Journal of international medical research, 2018, Volume: 46, Issue:4

    Topics: Aged; Asian People; Carcinoma, Non-Small-Cell Lung; Disease-Free Survival; Down-Regulation; Ethnicity; Female; Gene Expression Regulation, Neoplastic; Histones; Humans; Kaplan-Meier Estimate; Lung Neoplasms; Lysine; Male; Middle Aged; NAD; Neoplasm Metastasis; Prognosis; RNA, Messenger; Sirtuins; Survival Analysis

2018
STAM-binding protein regulates melanoma metastasis through SLUG stabilization.
    Biochemical and biophysical research communications, 2018, 12-09, Volume: 507, Issue:1-4

    Topics: Animals; Cell Line, Tumor; Cell Survival; Endosomal Sorting Complexes Required for Transport; Female; Humans; Lysine; Melanoma; Mice; Neoplasm Invasiveness; Neoplasm Metastasis; Protein Stability; Snail Family Transcription Factors; Ubiquitin Thiolesterase; Ubiquitination

2018
OTUB2 Promotes Cancer Metastasis via Hippo-Independent Activation of YAP and TAZ.
    Molecular cell, 2019, 01-03, Volume: 73, Issue:1

    Topics: Adaptor Proteins, Signal Transducing; Animals; Breast Neoplasms; Cell Differentiation; Cell Line, Tumor; Cell Movement; Epidermal Growth Factor; ErbB Receptors; Female; HEK293 Cells; Humans; Intracellular Signaling Peptides and Proteins; Lysine; Mice, Inbred BALB C; Mice, Nude; Mutation; Neoplasm Metastasis; Neoplastic Stem Cells; Phenotype; Phosphoproteins; Proteasome Endopeptidase Complex; Protein Binding; Protein Interaction Domains and Motifs; Proteolysis; Proto-Oncogene Proteins p21(ras); Signal Transduction; Sumoylation; Thiolester Hydrolases; Time Factors; Trans-Activators; Transcription Factors; Transcriptional Coactivator with PDZ-Binding Motif Proteins; YAP-Signaling Proteins

2019
Identification of selective and reversible LSD1 inhibitors with anti-metastasis activity by high-throughput docking.
    Bioorganic & medicinal chemistry letters, 2019, 02-15, Volume: 29, Issue:4

    Topics: Cell Line, Tumor; Demethylation; Enzyme Inhibitors; Histone Demethylases; Histones; Humans; Lysine; Methylation; Molecular Docking Simulation; Neoplasm Metastasis; Neoplasms; Structure-Activity Relationship

2019
KDM5D inhibit epithelial-mesenchymal transition of gastric cancer through demethylation in the promoter of Cul4A in male.
    Journal of cellular biochemistry, 2019, Volume: 120, Issue:8

    Topics: Animals; Cell Movement; Cullin Proteins; Demethylation; Down-Regulation; Epithelial-Mesenchymal Transition; Gene Expression Regulation, Neoplastic; HEK293 Cells; Histone Demethylases; Histones; Humans; Lysine; Male; Mice, Nude; Minor Histocompatibility Antigens; Neoplasm Invasiveness; Neoplasm Metastasis; Promoter Regions, Genetic; Stomach Neoplasms

2019
18F-DCFPyL PET/CT in a Single Large Metastasis With Prostate-Specific Antigen Level of 856 ng/mL.
    Clinical nuclear medicine, 2019, Volume: 44, Issue:10

    Topics: Aged; Glutamate Carboxypeptidase II; Humans; Lysine; Male; Neoplasm Metastasis; Positron Emission Tomography Computed Tomography; Prostate-Specific Antigen; Prostatic Neoplasms; Urea

2019
Concomitant Prostate Carcinoma and Follicular Lymphoma: "Flip-Flop" Appearances on PSMA and FDG PET/CT Scans.
    Clinical nuclear medicine, 2019, Volume: 44, Issue:10

    Topics: Aged; Fluorodeoxyglucose F18; Humans; Lymphoma, Follicular; Lysine; Male; Neoplasm Metastasis; Neoplasms, Second Primary; Positron Emission Tomography Computed Tomography; Prostatic Neoplasms; Urea

2019
Ubiquitylation of phosphatidylinositol 4-phosphate 5-kinase type I γ by HECTD1 regulates focal adhesion dynamics and cell migration.
    Journal of cell science, 2013, Jun-15, Volume: 126, Issue:Pt 12

    Topics: Animals; Cell Line; Cell Movement; CHO Cells; Cricetinae; Cricetulus; Focal Adhesions; HEK293 Cells; Humans; Integrin beta Chains; Lysine; Neoplasm Invasiveness; Neoplasm Metastasis; Phosphatidylinositol 4,5-Diphosphate; Phosphotransferases (Alcohol Group Acceptor); Talin; Ubiquitin-Protein Ligases; Ubiquitination

2013
Mechanisms of buffer therapy resistance.
    Neoplasia (New York, N.Y.), 2014, Volume: 16, Issue:4

    Topics: Animals; Buffers; Cell Line, Tumor; Cell Movement; Disease Models, Animal; Humans; Hydrogen-Ion Concentration; Lysine; Melanoma, Experimental; Mice; Neoplasm Metastasis; Neoplasms

2014
Matrix softness regulates plasticity of tumour-repopulating cells via H3K9 demethylation and Sox2 expression.
    Nature communications, 2014, Aug-06, Volume: 5

    Topics: Animals; Biosensing Techniques; Cell Line, Tumor; Cell Proliferation; Disease Progression; DNA Methylation; Female; Fibrin; Fluorescence Resonance Energy Transfer; Gene Silencing; Histone-Lysine N-Methyltransferase; Histones; Integrin beta1; Lysine; Melanoma; Melanoma, Experimental; Methylation; Mice; Mice, Inbred C57BL; Neoplasm Metastasis; Neoplasm Transplantation; Neoplastic Stem Cells; Promoter Regions, Genetic; RNA, Small Interfering; Skin Neoplasms; SOXB1 Transcription Factors; Time Factors

2014
High-resolution profiling of histone h3 lysine 36 trimethylation in metastatic renal cell carcinoma.
    Oncogene, 2016, Mar-24, Volume: 35, Issue:12

    Topics: Carcinoma, Renal Cell; Chromatin Immunoprecipitation; Cohort Studies; Histones; Humans; Kidney Neoplasms; Lysine; Methylation; Neoplasm Metastasis

2016
Detection of 18F-FDG PET/CT Occult Lesions With 18F-DCFPyL PET/CT in a Patient With Metastatic Renal Cell Carcinoma.
    Clinical nuclear medicine, 2016, Volume: 41, Issue:1

    Topics: Carcinoma, Renal Cell; Fluorodeoxyglucose F18; Humans; Lysine; Male; Middle Aged; Multimodal Imaging; Neoplasm Metastasis; Positron-Emission Tomography; Radiopharmaceuticals; Tomography, X-Ray Computed; Urea

2016
Aspirin, lysine, mifepristone and doxycycline combined can effectively and safely prevent and treat cancer metastasis: prevent seeds from gemmating on soil.
    Oncotarget, 2015, Nov-03, Volume: 6, Issue:34

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Aspirin; Doxycycline; Drug Interactions; Female; Human Umbilical Vein Endothelial Cells; Humans; Lysine; Male; Melanoma; Melanoma, Experimental; Mice; Mice, Inbred C57BL; Mifepristone; Neoplasm Metastasis; Random Allocation; Rats; Rats, Sprague-Dawley

2015
Quantitative Histone Mass Spectrometry Identifies Elevated Histone H3 Lysine 27 (Lys27) Trimethylation in Melanoma.
    Molecular & cellular proteomics : MCP, 2016, Volume: 15, Issue:3

    Topics: Cadherins; Cell Line, Tumor; Core Binding Factor Alpha 1 Subunit; Enhancer of Zeste Homolog 2 Protein; Epigenesis, Genetic; Gene Expression Regulation, Neoplastic; Histones; Humans; Lysine; Mass Spectrometry; Methylation; Multiple Myeloma; Neoplasm Metastasis; Protein Processing, Post-Translational; Up-Regulation

2016
SET8 induces epithelial‑mesenchymal transition and enhances prostate cancer cell metastasis by cooperating with ZEB1.
    Molecular medicine reports, 2016, Volume: 13, Issue:2

    Topics: Cadherins; Cell Line, Tumor; Epithelial-Mesenchymal Transition; Gene Expression Regulation, Neoplastic; Gene Knockdown Techniques; Histone-Lysine N-Methyltransferase; Histones; Homeodomain Proteins; Humans; Lysine; Male; Methylation; Neoplasm Metastasis; Prostatic Neoplasms; Protein Binding; Transcription Factors; Transcription, Genetic; Vimentin; Zinc Finger E-box-Binding Homeobox 1

2016
The hypusine cascade promotes cancer progression and metastasis through the regulation of RhoA in squamous cell carcinoma.
    Oncogene, 2016, 10-06, Volume: 35, Issue:40

    Topics: Adult; Aged; Animals; Carcinoma, Squamous Cell; Cell Line, Tumor; Cell Movement; Cell Proliferation; Diamines; Disease Progression; Esophageal Neoplasms; Esophageal Squamous Cell Carcinoma; Female; Gene Expression Regulation, Neoplastic; Humans; Lysine; Male; Mice; Middle Aged; Neoplasm Metastasis; Oxidoreductases Acting on CH-NH Group Donors; rhoA GTP-Binding Protein; Signal Transduction

2016
Global-scale profiling of differential expressed lysine acetylated proteins in colorectal cancer tumors and paired liver metastases.
    Journal of proteomics, 2016, 06-16, Volume: 142

    Topics: Acetylation; Binding Sites; Biopsy; Colorectal Neoplasms; Gene Expression Regulation; Humans; Liver Neoplasms; Lysine; Metabolic Networks and Pathways; Neoplasm Metastasis; Neoplasm Proteins; Protein Interaction Maps; Protein Processing, Post-Translational; Proteome

2016
MOF Acetylates the Histone Demethylase LSD1 to Suppress Epithelial-to-Mesenchymal Transition.
    Cell reports, 2016, 06-21, Volume: 15, Issue:12

    Topics: Acetylation; Cadherins; Cell Line, Tumor; Disease Progression; Down-Regulation; Embryo, Mammalian; Epithelial Cells; Epithelial-Mesenchymal Transition; Fibroblasts; Gene Expression Regulation, Neoplastic; Histone Acetyltransferases; Histone Demethylases; Histones; Humans; Lysine; Methylation; Multiprotein Complexes; Mutation; Neoplasm Invasiveness; Neoplasm Metastasis; Nucleosomes

2016
HDAC6 Deacetylates HMGN2 to Regulate Stat5a Activity and Breast Cancer Growth.
    Molecular cancer research : MCR, 2016, Volume: 14, Issue:10

    Topics: Acetylation; Animals; Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; Female; Gene Expression Regulation, Neoplastic; Histone Deacetylase 6; Histone Deacetylases; HMGN2 Protein; Humans; Lysine; MCF-7 Cells; Mice; Neoplasm Metastasis; Neoplasm Transplantation; STAT5 Transcription Factor; Transcription, Genetic; Tumor Suppressor Proteins

2016
A New Chromatin-Cytoskeleton Link in Cancer.
    Molecular cancer research : MCR, 2016, Volume: 14, Issue:12

    Topics: Chromatin; Cytoskeleton; Genomic Instability; Histone-Lysine N-Methyltransferase; Histones; Humans; Lysine; Methylation; Mutation; Neoplasm Invasiveness; Neoplasm Metastasis; Neoplasms; Tubulin

2016
Kinetic isotope effects reveal early transition state of protein lysine methyltransferase SET8.
    Proceedings of the National Academy of Sciences of the United States of America, 2016, 12-27, Volume: 113, Issue:52

    Topics: Binding, Competitive; Catalysis; Cell Cycle; Computer Simulation; Histone-Lysine N-Methyltransferase; Histones; Humans; Isotopes; Kinetics; Lysine; Methylation; Models, Molecular; Models, Theoretical; Neoplasm Metastasis; Peptides; Protein Structure, Secondary; S-Adenosylmethionine; Software; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Substrate Specificity

2016
Dose-dependent, complete response to imatinib of a metastatic mucosal melanoma with a K642E KIT mutation.
    Pigment cell & melanoma research, 2008, Volume: 21, Issue:4

    Topics: Aged; Amino Acid Substitution; Anus Neoplasms; Benzamides; Dose-Response Relationship, Drug; Female; Glutamic Acid; Humans; Imatinib Mesylate; Intestinal Mucosa; Lysine; Melanoma; Neoplasm Metastasis; Piperazines; Point Mutation; Proto-Oncogene Proteins c-kit; Pyrimidines; Remission Induction

2008
The basic C-terminal amino acids of calcium-binding protein S100A4 promote metastasis.
    Carcinogenesis, 2008, Volume: 29, Issue:12

    Topics: Amino Acid Sequence; Animals; Binding Sites; Blotting, Western; Cell Line, Tumor; Cell Movement; Humans; Lysine; Molecular Motor Proteins; Molecular Sequence Data; Mutagenesis, Site-Directed; Myosin Heavy Chains; Neoplasm Invasiveness; Neoplasm Metastasis; Polymerase Chain Reaction; Protein Binding; Rats; S100 Calcium-Binding Protein A4; S100 Proteins; Transfection

2008
Prognostic significance of global histone modifications in resected squamous cell carcinoma of the esophagus.
    Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc, 2009, Volume: 22, Issue:2

    Topics: Acetylation; Adult; Aged; Aged, 80 and over; Biomarkers, Tumor; Carcinoma, Squamous Cell; Cell Differentiation; Esophageal Neoplasms; Esophagectomy; Female; Histones; Humans; Immunohistochemistry; Kaplan-Meier Estimate; Lymphatic Metastasis; Lysine; Male; Methylation; Middle Aged; Neoplasm Metastasis; Neoplasm Staging; Protein Processing, Post-Translational; Retrospective Studies; Time Factors; Treatment Outcome

2009
Genomic loss of microRNA-101 leads to overexpression of histone methyltransferase EZH2 in cancer.
    Science (New York, N.Y.), 2008, Dec-12, Volume: 322, Issue:5908

    Topics: 3' Untranslated Regions; Algorithms; Breast Neoplasms; Cell Line, Tumor; Disease Progression; DNA-Binding Proteins; Enhancer of Zeste Homolog 2 Protein; Epigenesis, Genetic; Female; Gene Expression Regulation, Neoplastic; Genome, Human; Histones; Humans; Lysine; Male; Methylation; MicroRNAs; Neoplasm Metastasis; Neoplasms; Polycomb Repressive Complex 2; Promoter Regions, Genetic; Prostatic Neoplasms; RNA, Small Interfering; Stomach Neoplasms; Transcription Factors

2008
Quantitative proteome analysis of HCC cell lines with different metastatic potentials by SILAC.
    Proteomics, 2008, Volume: 8, Issue:23-24

    Topics: Blotting, Western; Carcinoma, Hepatocellular; Cell Line, Tumor; Enzyme-Linked Immunosorbent Assay; Humans; Isotope Labeling; Liver Neoplasms; Lysine; Neoplasm Metastasis; Neoplasm Proteins; Proteome; ROC Curve; Subcellular Fractions

2008
Synthesis and evaluation of myxochelin analogues as antimetastatic agents.
    Bioorganic & medicinal chemistry, 2009, Apr-01, Volume: 17, Issue:7

    Topics: Administration, Oral; Animals; Antineoplastic Agents; Catechols; Cell Line, Tumor; Lung Neoplasms; Lysine; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Matrix Metalloproteinase Inhibitors; Mice; Neoplasm Metastasis; Stereoisomerism; Structure-Activity Relationship

2009
Domain interplay mediated by an essential disulfide linkage is critical for the activity and secretion of the metastasis-promoting enzyme autotaxin.
    The Journal of biological chemistry, 2009, May-22, Volume: 284, Issue:21

    Topics: Amino Acid Sequence; Animals; Biocatalysis; Cell Line; Cysteine; Disulfides; Dithiothreitol; Endopeptidases; Enzyme Activation; Humans; Lysine; Molecular Sequence Data; Neoplasm Metastasis; Phosphoric Diester Hydrolases; Protein Structure, Tertiary; Pyrophosphatases; Rats; Structure-Activity Relationship

2009
Lysine 63-linked ubiquitination is important for arachidonic acid-induced cellular adhesion and migration.
    Biochemistry and cell biology = Biochimie et biologie cellulaire, 2010, Volume: 88, Issue:6

    Topics: Arachidonic Acid; Breast Neoplasms; Cell Adhesion; Cell Line, Tumor; Cell Movement; Collagen Type IV; Enzyme Inhibitors; Extracellular Matrix; Humans; Lysine; Neoplasm Metastasis; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Ubiquitin; Ubiquitin-Activating Enzymes; Ubiquitination

2010
H3K27me3 protein is a promising predictive biomarker of patients' survival and chemoradioresistance in human nasopharyngeal carcinoma.
    Molecular medicine (Cambridge, Mass.), 2011, Volume: 17, Issue:11-12

    Topics: Biomarkers, Tumor; Blotting, Western; Carcinoma; Cell Line, Tumor; Drug Resistance, Neoplasm; Female; Histones; Humans; Immunohistochemistry; Lysine; Male; Methylation; Middle Aged; Models, Biological; Multivariate Analysis; Nasopharyngeal Carcinoma; Nasopharyngeal Neoplasms; Neoplasm Metastasis; Predictive Value of Tests; Prognosis; Radiation Tolerance; ROC Curve; Survival Analysis; Treatment Outcome

2011
RhoGDI SUMOylation at Lys-138 increases its binding activity to Rho GTPase and its inhibiting cancer cell motility.
    The Journal of biological chemistry, 2012, Apr-20, Volume: 287, Issue:17

    Topics: Cell Line, Tumor; Cell Movement; Gene Expression Regulation, Neoplastic; Guanine Nucleotide Dissociation Inhibitors; Humans; Lysine; Models, Biological; Neoplasm Invasiveness; Neoplasm Metastasis; Neoplasms; rho GTP-Binding Proteins; rho Guanine Nucleotide Dissociation Inhibitor alpha; rho-Specific Guanine Nucleotide Dissociation Inhibitors; Sumoylation; Wound Healing; X-Linked Inhibitor of Apoptosis Protein

2012
Post-translational modifications of recombinant human lysyl oxidase-like 2 (rhLOXL2) secreted from Drosophila S2 cells.
    The Journal of biological chemistry, 2013, Feb-22, Volume: 288, Issue:8

    Topics: Amino Acid Oxidoreductases; Animals; Breast Neoplasms; Carbohydrates; Catalytic Domain; Cell Line; Drosophila melanogaster; Glycosylation; Humans; Lysine; Mass Spectrometry; Mutagenesis, Site-Directed; Neoplasm Invasiveness; Neoplasm Metastasis; Peptides; Polysaccharides; Protein Folding; Protein Processing, Post-Translational; Quinones; Recombinant Proteins; Solvents

2013
The metastasis suppressor NM23-H1 possesses 3'-5' exonuclease activity.
    The Journal of biological chemistry, 2004, Apr-23, Volume: 279, Issue:17

    Topics: Adenosine Triphosphate; Chromatography, Gel; Chromatography, High Pressure Liquid; Circular Dichroism; Deoxyadenosines; DNA; DNA Repair; Exonucleases; Humans; Lysine; Magnesium; Models, Genetic; Mutagenesis, Site-Directed; Mutation; Neoplasm Metastasis; NM23 Nucleoside Diphosphate Kinases; Nucleoside-Diphosphate Kinase; Oligodeoxyribonucleotides; Protein Structure, Tertiary; Proteins; Recombinant Proteins; Time Factors

2004
Metastasis-associated protein S100A4 induces angiogenesis through interaction with Annexin II and accelerated plasmin formation.
    The Journal of biological chemistry, 2005, May-27, Volume: 280, Issue:21

    Topics: Annexin A2; Binding Sites; Capillaries; Cell Membrane; Endothelial Cells; Fibrinolysin; Fluorescent Antibody Technique; Humans; Immunosorbent Techniques; Kinetics; Lysine; Magnetic Resonance Spectroscopy; Microcirculation; Mutagenesis; Neoplasm Metastasis; Neovascularization, Pathologic; Plasminogen; Recombinant Proteins; Reverse Transcriptase Polymerase Chain Reaction; S100 Calcium-Binding Protein A4; S100 Proteins; Structure-Activity Relationship; Temporal Lobe; Tissue Plasminogen Activator

2005
Targeted delivery to PEPT1-overexpressing cells: acidic, basic, and secondary floxuridine amino acid ester prodrugs.
    Molecular cancer therapeutics, 2005, Volume: 4, Issue:4

    Topics: Amino Acids; Animals; Antimetabolites, Antineoplastic; Caco-2 Cells; Cell Line; Cell Line, Tumor; Cell Proliferation; Chromatography, High Pressure Liquid; Dogs; Floxuridine; HeLa Cells; Humans; Hydrogen-Ion Concentration; Hydrolysis; Inhibitory Concentration 50; Lysine; Models, Chemical; Neoplasm Metastasis; Nucleosides; Oligopeptides; Pancreatic Neoplasms; Peptide Transporter 1; Prodrugs; Proline; Symporters; Time Factors

2005
Inhibitory effect of a mixture containing ascorbic acid, lysine, proline and green tea extract on critical parameters in angiogenesis.
    Oncology reports, 2005, Volume: 14, Issue:4

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Ascorbic Acid; Cell Line, Tumor; Cell Proliferation; Chick Embryo; Chorioallantoic Membrane; Collagen; Dose-Response Relationship, Drug; Drug Combinations; Extracellular Matrix; Fibroblast Growth Factor 2; Formaldehyde; Humans; Immunohistochemistry; In Vitro Techniques; Laminin; Lysine; Matrix Metalloproteinases; Mice; Mice, Inbred C57BL; Mice, Nude; Neoplasm Invasiveness; Neoplasm Metastasis; Neoplasm Transplantation; Neovascularization, Pathologic; Osteosarcoma; Plant Extracts; Platelet-Derived Growth Factor; Proline; Proteoglycans; Tea; Tetrazolium Salts; Thiazoles; Time Factors; Transforming Growth Factor beta; Transforming Growth Factor beta1; Vascular Endothelial Growth Factor A

2005
Inhibition of tumor growth and elimination of multiple metastases in human prostate and breast xenografts by systemic inoculation of a host defense-like lytic peptide.
    Cancer research, 2006, May-15, Volume: 66, Issue:10

    Topics: Adenocarcinoma; Amino Acid Sequence; Animals; Breast Neoplasms; Cell Growth Processes; Cell Line, Tumor; Female; Humans; Leucine; Lung Neoplasms; Lysine; Male; Membrane Potentials; Mice; Mice, SCID; Neoplasm Metastasis; Peptides; Phosphatidylserines; Prostate-Specific Antigen; Prostatic Neoplasms; Xenograft Model Antitumor Assays

2006
JMJD3 is a histone H3K27 demethylase.
    Cell research, 2007, Volume: 17, Issue:10

    Topics: Binding Sites; Blotting, Western; Databases, Factual; DNA-Binding Proteins; Glutathione Transferase; HeLa Cells; Histones; Humans; Immunohistochemistry; Jumonji Domain-Containing Histone Demethylases; Lysine; Male; Methylation; Mutation; Neoplasm Metastasis; Oxidoreductases, N-Demethylating; Prostatic Neoplasms; Recombinant Fusion Proteins; Transfection

2007
The type I TGF-beta receptor is covalently modified and regulated by sumoylation.
    Nature cell biology, 2008, Volume: 10, Issue:6

    Topics: Animals; Chlorocebus aethiops; COS Cells; Cytoplasm; Gene Expression Regulation; Humans; Lysine; Mice; Models, Biological; Neoplasm Metastasis; Phosphorylation; Protein Binding; Protein Serine-Threonine Kinases; Receptor, Transforming Growth Factor-beta Type I; Receptors, Transforming Growth Factor beta; SUMO-1 Protein; Transforming Growth Factor beta

2008
Production and characterization of novel anti-prostate-specific antigen (PSA) monoclonal antibodies that do not detect internally cleaved Lys145-Lys146 inactive PSA.
    Clinical chemistry, 2000, Volume: 46, Issue:10

    Topics: Amino Acid Sequence; Animals; Antibodies, Monoclonal; Antibody Specificity; Epitope Mapping; Immunoassay; Lysine; Mice; Mice, Inbred BALB C; Models, Molecular; Molecular Sequence Data; Neoplasm Metastasis; Peptide Mapping; Prostate-Specific Antigen; Tumor Cells, Cultured

2000
Differences in uptake of aminoacids by patients with various forms of cancer.
    Neoplasma, 1978, Volume: 25, Issue:5

    Topics: Amino Acids; Female; Humans; Lysine; Male; Neoplasm Metastasis; Neoplasms; Valine

1978
Fibrinogen and metastases.
    Journal of medicine, 1974, Volume: 5, Issue:1

    Topics: Animals; Cell Line; Culture Media; Female; Fibrinogen; gamma-Glutamyltransferase; Humans; In Vitro Techniques; Lysine; Mitochondria; Neoplasm Metastasis; Neoplasm Transplantation; Neoplasms; Neoplasms, Experimental; Neuroblastoma; Oxygen Consumption; Plasmacytoma; Pregnancy; Thrombin; Thrombosis; Wound Healing

1974
Evidence for the presence of tumor peptides with corticotropin-releasing-factor-like activity in the ectopic ACTH syndrome.
    The New England journal of medicine, 1971, Aug-19, Volume: 285, Issue:8

    Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Adrenocorticotropic Hormone; Amino Acids; Animals; Biological Assay; Carcinoma, Bronchogenic; Corticotropin-Releasing Hormone; Dexamethasone; Electrophoresis; Feedback; Hormones, Ectopic; Humans; Lung Neoplasms; Lysine; Metyrapone; Neoplasm Metastasis; Neoplasm Proteins; Pancreatic Neoplasms; Peptides; Rats; Vasopressins

1971
Transglutaminase and tumor growth.
    Annals of the New York Academy of Sciences, 1972, Dec-08, Volume: 202

    Topics: Animals; Blood Coagulation; Cross Reactions; Dipeptides; Glutamine; Glycine; Glycosides; Guinea Pigs; Immunization; Immunodiffusion; Liver; Lysine; Mice; Neoplasm Metastasis; Neoplasms, Experimental; Peptides; Plasmacytoma; Putrescine; Rabbits; Transferases

1972
[Modification of some free amino acids in the serum of cancer patients under the influence of glucose on tumoral metabolism].
    Clinica chimica acta; international journal of clinical chemistry, 1969, Volume: 23, Issue:2

    Topics: Alanine; Amino Acids; Breast Neoplasms; Chromatography, Paper; Dietary Carbohydrates; Dietary Proteins; Female; Gastrointestinal Neoplasms; Glucose; Glycolysis; Leucine; Lung Neoplasms; Lysine; Neoplasm Metastasis; Perfusion; Stimulation, Chemical; Uterine Neoplasms; Valine

1969