lysine has been researched along with Myelodysplastic Syndromes in 6 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 5 (83.33) | 24.3611 |
| 2020's | 1 (16.67) | 2.80 |
| Authors | Studies |
|---|---|
| Acusta, A; Ballas, M; Borthakur, G; Collingwood, T; de la Fuente Burguera, A; Del Buono, H; Dhar, A; Ferron-Brady, G; Karpinich, NO; Kruger, RG; Mohammad, HP; Roboz, GJ; Sanz, G; Verma, A; Wei, AH; Yee, K | 1 |
| Chen, S; Chen, X; Greenblatt, S; Guo, Y; Guo, Z; He, F; Li, J; Li, Z; Man, N; Morey, L; Nimer, SD; Shi, H; Sun, Y; Wang, L; Wang, QF; Wang, QT; Williams, S; Xu, M; Yang, FC; Yang, H; Yu, P; Zhang, P; Zhou, Y | 1 |
| Iriyama, C; Kiyoi, H; Shimada, K; Shirahata-Adachi, M; Suzuki, Y; Tomita, A | 1 |
| Bueso-Ramos, C; Chen, R; Dimicoli, S; Ebert, B; Fang, Z; Ganan-Gomez, I; Garcia-Manero, G; Jia, Y; Kantarjian, H; Levine, R; Neuberg, D; Nguyen, M; Pierce, S; Wang, H; Wei, Y; Yang, H; Zheng, H | 1 |
| Joshi, D; Korgaonkar, S; Shanmukhaiah, C; Vundinti, BR | 1 |
| Elf, S; Hsieh, JJ; Huang, G; Lee, J; Liu, Y; Menendez, S; Nimer, SD; Osato, M; Sashida, G; Tenen, DG; Wang, L; Xu, H; Yan, X; Yang, Y; Zhang, P; Zhang, Y; Zhao, X | 1 |
1 trial(s) available for lysine and Myelodysplastic Syndromes
| Article | Year |
|---|---|
Phase I trials of the lysine-specific demethylase 1 inhibitor, GSK2879552, as mono- and combination-therapy in relapsed/refractory acute myeloid leukemia or high-risk myelodysplastic syndromes.
Topics: Benzoates; Cyclopropanes; Humans; Leukemia, Myeloid, Acute; Lysine; Myelodysplastic Syndromes | 2022 |
5 other study(ies) available for lysine and Myelodysplastic Syndromes
| Article | Year |
|---|---|
Loss of Asxl2 leads to myeloid malignancies in mice.
Topics: Animals; Cell Lineage; Cell Self Renewal; Disease Progression; Gene Deletion; Gene Expression Regulation, Leukemic; Hematopoiesis; Hematopoietic Stem Cells; Histones; Leukemia, Myeloid, Acute; Lysine; Mice; Myelodysplastic Syndromes; Myeloid Cells; Protein Processing, Post-Translational; Repressor Proteins; Transcription, Genetic | 2017 |
Altered EZH2 splicing and expression is associated with impaired histone H3 lysine 27 tri-Methylation in myelodysplastic syndrome.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Alternative Splicing; Biomarkers, Tumor; DNA Methylation; Enhancer of Zeste Homolog 2 Protein; Epigenesis, Genetic; Female; Follow-Up Studies; Histones; Humans; Lysine; Male; Middle Aged; Mutation; Myelodysplastic Syndromes; Prognosis; Tumor Cells, Cultured; Young Adult | 2017 |
Global H3K4me3 genome mapping reveals alterations of innate immunity signaling and overexpression of JMJD3 in human myelodysplastic syndrome CD34+ cells.
Topics: Antigens, CD34; Blotting, Western; Bone Marrow; Chromatin Immunoprecipitation; Chromosome Mapping; Histones; Humans; Immunity, Innate; Immunoenzyme Techniques; Jumonji Domain-Containing Histone Demethylases; Lysine; Myelodysplastic Syndromes; NF-kappa B; Promoter Regions, Genetic; Real-Time Polymerase Chain Reaction; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tumor Cells, Cultured | 2013 |
Association of XPD (Lys751Gln) and XRCC1 (Arg280His) gene polymorphisms in myelodysplastic syndrome.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Arginine; Case-Control Studies; DNA-Binding Proteins; Female; Genetic Association Studies; Glutamine; Histidine; Humans; Lysine; Male; Middle Aged; Myelodysplastic Syndromes; Polymorphism, Single Nucleotide; X-ray Repair Cross Complementing Protein 1; Xeroderma Pigmentosum Group D Protein; Young Adult | 2016 |
The ability of MLL to bind RUNX1 and methylate H3K4 at PU.1 regulatory regions is impaired by MDS/AML-associated RUNX1/AML1 mutations.
Topics: Acute Disease; Blotting, Western; Cell Line; Cell Line, Tumor; Chromatin Immunoprecipitation; Core Binding Factor Alpha 2 Subunit; Core Binding Factor beta Subunit; Gene Expression; HEK293 Cells; Histone-Lysine N-Methyltransferase; Histones; Humans; Leukemia, Myeloid; Lysine; Methylation; Mutation; Myelodysplastic Syndromes; Myeloid-Lymphoid Leukemia Protein; Protein Binding; Proto-Oncogene Proteins; Regulatory Sequences, Nucleic Acid; Reverse Transcriptase Polymerase Chain Reaction; Trans-Activators | 2011 |