lysine has been researched along with Multiple Myeloma in 35 studies
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 20 (57.14) | 18.7374 |
1990's | 0 (0.00) | 18.2507 |
2000's | 1 (2.86) | 29.6817 |
2010's | 13 (37.14) | 24.3611 |
2020's | 1 (2.86) | 2.80 |
Authors | Studies |
---|---|
Anderson, KC; Durbin, AD; Gryder, BE; Hideshima, T; Hino, S; Johansson, C; Kawano, Y; Khan, J; Kim, Y; Kurata, K; Lauberth, S; Li, D; Masuda, T; Matsuoka, M; Minami, T; Munshi, NC; Nakao, M; Ogiya, D; Ohguchi, H; Ohtsuki, S; Oppermann, U; Park, PMC; Pei, C; Qi, J; Samur, MK; Tai, YT; Usuki, S; Wang, T; Wimalasena, VK; Zhang, X | 1 |
Cao, B; Du, Y; Juan, J; Mao, X; Moran, MF; Tong, J; Wang, S; Xu, Y; Zeng, Y; Zhang, Z | 1 |
Bulic, M; Dupéré-Richer, D; Ezponda, T; Huang, X; Keats, J; Kelleher, N; Licht, JD; Maji, S; Nabet, B; Occhionorelli, M; Oyer, J; Patel, T; Popovic, R; Riva, A; Shah, MY; Small, EC; Tonon, G; Varghese, N; Will, CM; Zheng, Y | 1 |
Burke, TR; Goydel, RS; Hymel, D; Li, X; Nanna, AR; Pedzisa, L; Rader, C; Roush, WR; Walseng, E | 1 |
Bulic, M; Calogero, RA; Carrara, M; Elemento, O; Ezponda, T; Giannopoulou, EG; Hua, Y; Jiang, Y; Kath, WL; Kelleher, NL; Licht, JD; Martinez-Garcia, E; Popovic, R; Shah, MY; Small, EC; Wang, JP; Will, CM; Zhang, Q; Zheng, Y | 1 |
Cao, B; Chen, G; Han, K; Li, J; Li, S; Mao, X; Moran, MF; Tang, J; Tong, J; Wu, D; Xu, X; Yang, C; Zhang, Z; Zhou, H | 1 |
Donoghue, DJ; Gallo, LH; Haas, M; Meyer, AN; Motamedchaboki, K; Nelson, KN | 1 |
Canterbury, J; Compton, PD; Fellers, RT; Fornelli, L; Kelleher, NL; Licht, JD; Mullen, C; Senko, MW; Sharma, S; Thomas, PM; Zabrouskov, V; Zheng, Y | 1 |
Avaritt, NL; Byrum, SD; Davis, L; Mackintosh, SG; Mahmoud, F; Orr, LM; Reynolds, M; Sengupta, D; Shalin, SC; Shields, B; Tackett, AJ | 1 |
Acharya, C; Acharya, P; Adamia, S; Anderson, KC; Ballestrero, A; Bhasin, MK; Cagnetta, A; Carrasco, R; Cea, M; Chauhan, D; Fulciniti, M; Gobbi, M; Hideshima, T; Lemoli, RM; Monacelli, F; Munshi, A; Munshi, N; Nencioni, A; Ohguchi, H; Richardson, P; Tai, YT; Zhong, L | 1 |
Agarwal, P; Alzrigat, M; Brown, PJ; Enroth, S; Jernberg-Wiklund, H; Jin, J; Kalushkova, A; Ma, A; Nilsson, K; Öberg, F; Österborg, A; Párraga, AA; Singh, U; Ungerstedt, J | 1 |
Davern, S; Murphy, CL; O'Neill, H; Solomon, A; Wall, JS; Weiss, DT | 1 |
Chen, K; Cheung, P; Garcia, BA; Gozani, O; Kioi, M; Kuo, AJ; Lauring, J; Li, W; Park, BH; Shi, X; Xi, Y; Zee, BM | 1 |
Chen, Y; Li, R; Liu, Y; Wen, L; Zeng, LL; Zhang, C; Zhao, F | 1 |
FAHEY, JL; NATHANS, D; POTTER, M | 1 |
GREGOIRE, F; LAMBERT, PP | 1 |
Bi, JX; Liu, YH; Yuan, JQ; Zeng, AP | 1 |
Edmundson, AB; Ely, KR; Peabody, DS | 1 |
Farver, O; Pecht, I; Zidovetzki, R | 1 |
Claflin, JL; Davie, JM; Kinsky, SC; Uemura, K | 1 |
Ein, D; Messner, RP; Natvig, JB; Wlliams, RC | 1 |
Andersen, BR; McAninch, JR; Patterson, R | 1 |
Bridges, SH; Little, JR | 1 |
Cotton, RG; Milstein, C; Secher, DS | 1 |
Tischendorf, FW; Tischendorf, MM | 1 |
Capetillo, S; Jirgensons, B; Nakagawa, Y | 1 |
Diesselhoff den Dulk, MM; Lai A Fat, RF; Rádl, J; van der Berg, P; van Furth, R | 1 |
Cowan, NJ; Milstein, C | 1 |
Cotton, RG; Cowan, NJ; Milstein, C; Secher, DS | 1 |
Chen, BL; Poljak, RJ | 1 |
Hollander, VP; Yamada, A; Yamada, H | 1 |
Boyd, MM; Rea, JS; Stein, R; Terry, WD | 1 |
Hadler, NM; Metzger, H | 1 |
Kabat, EA; Wu, TT | 1 |
Bürgi, W; Schärer, HU | 1 |
35 other study(ies) available for lysine and Multiple Myeloma
Article | Year |
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Lysine Demethylase 5A is Required for MYC Driven Transcription in Multiple Myeloma.
Topics: Cyclin-Dependent Kinase 9; Cyclin-Dependent Kinase-Activating Kinase; Cyclin-Dependent Kinases; Genes, cdc; Humans; Lysine; Methylation; Multiple Myeloma; Proto-Oncogene Proteins c-myc; Retinoblastoma-Binding Protein 2; RNA Polymerase II | 2021 |
Inhibition of the deubiquitinase USP5 leads to c-Maf protein degradation and myeloma cell apoptosis.
Topics: Apoptosis; Endopeptidases; Gene Knockdown Techniques; HEK293 Cells; Humans; Lysine; Molecular Targeted Therapy; Multiple Myeloma; Polyubiquitin; Protein Binding; Protein Domains; Protein Stability; Proteolysis; Proto-Oncogene Proteins c-maf; Structure-Activity Relationship; Transcription, Genetic; Ubiquitination | 2017 |
UTX/KDM6A Loss Enhances the Malignant Phenotype of Multiple Myeloma and Sensitizes Cells to EZH2 inhibition.
Topics: Animals; Carcinogenesis; Cell Adhesion; Cell Dedifferentiation; Cell Line, Tumor; Cell Proliferation; Cell Survival; Clone Cells; Enhancer of Zeste Homolog 2 Protein; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Histone Demethylases; Histones; Indazoles; Interferon Regulatory Factors; Lysine; Methylation; Mice; Mice, Inbred NOD; Mice, SCID; Multiple Myeloma; Mutation; Nuclear Proteins; Phenotype; Pyridones; Transcription, Genetic | 2017 |
Harnessing a catalytic lysine residue for the one-step preparation of homogeneous antibody-drug conjugates.
Topics: Animals; Antineoplastic Agents; beta-Lactams; Catalysis; Cell Line, Tumor; Chemistry, Pharmaceutical; Epitopes, T-Lymphocyte; Female; Humans; Hydrogen-Ion Concentration; Immunoconjugates; K562 Cells; Lymphoma, Non-Hodgkin; Lysine; Mice; Multiple Myeloma; Mutation; Neoplasm Transplantation; Pharmaceutical Preparations; Syndecan-1; Trastuzumab; Xenograft Model Antitumor Assays | 2017 |
Histone methyltransferase MMSET/NSD2 alters EZH2 binding and reprograms the myeloma epigenome through global and focal changes in H3K36 and H3K27 methylation.
Topics: Animals; Cell Line; Cell Transformation, Neoplastic; Chromatin; DNA Methylation; Epigenesis, Genetic; Female; HEK293 Cells; Histone-Lysine N-Methyltransferase; Histones; Humans; Lysine; Mice; Mice, Inbred C57BL; Multiple Myeloma; Polycomb Repressive Complex 2; Protein Binding; RNA, Small Interfering | 2014 |
Ubiquitination of the transcription factor c-MAF is mediated by multiple lysine residues.
Topics: Amino Acid Sequence; Cell Line, Tumor; HEK293 Cells; HeLa Cells; Humans; Lysine; Lysosomes; Molecular Sequence Data; Multiple Myeloma; Mutation; Proteasome Endopeptidase Complex; Proto-Oncogene Proteins c-maf; Transfection; Ubiquitin; Ubiquitination | 2014 |
Novel Lys63-linked ubiquitination of IKKβ induces STAT3 signaling.
Topics: Amino Acid Sequence; Chromatography, High Pressure Liquid; HEK293 Cells; Humans; I-kappa B Kinase; Lysine; Molecular Sequence Data; Multiple Myeloma; Mutation; NF-kappa B; Peptides; Phosphorylation; Protein Binding; Signal Transduction; STAT3 Transcription Factor; Tandem Mass Spectrometry; Transcription Factors; Ubiquitin-Conjugating Enzymes; Ubiquitination | 2014 |
Unabridged Analysis of Human Histone H3 by Differential Top-Down Mass Spectrometry Reveals Hypermethylated Proteoforms from MMSET/NSD2 Overexpression.
Topics: Cell Line, Tumor; Epigenesis, Genetic; Histone-Lysine N-Methyltransferase; Histones; Humans; Lysine; Mass Spectrometry; Methylation; Multiple Myeloma; Proteome; Repressor Proteins; Up-Regulation | 2016 |
Quantitative Histone Mass Spectrometry Identifies Elevated Histone H3 Lysine 27 (Lys27) Trimethylation in Melanoma.
Topics: Cadherins; Cell Line, Tumor; Core Binding Factor Alpha 1 Subunit; Enhancer of Zeste Homolog 2 Protein; Epigenesis, Genetic; Gene Expression Regulation, Neoplastic; Histones; Humans; Lysine; Mass Spectrometry; Methylation; Multiple Myeloma; Neoplasm Metastasis; Protein Processing, Post-Translational; Up-Regulation | 2016 |
Evidence for a role of the histone deacetylase SIRT6 in DNA damage response of multiple myeloma cells.
Topics: Acetylation; Cell Line, Tumor; Cell Proliferation; DNA Damage; DNA Repair; Doxorubicin; ets-Domain Protein Elk-1; Histones; Humans; Lysine; MAP Kinase Signaling System; Models, Biological; Multiple Myeloma; Mutagens; Prognosis; Sirtuins | 2016 |
Genome-wide profiling of histone H3 lysine 27 and lysine 4 trimethylation in multiple myeloma reveals the importance of Polycomb gene targeting and highlights EZH2 as a potential therapeutic target.
Topics: Chromatin; Down-Regulation; Enhancer of Zeste Homolog 2 Protein; Enzyme Inhibitors; Gene Expression Profiling; Histones; Humans; Lysine; Methylation; Molecular Targeted Therapy; Multiple Myeloma; Polycomb-Group Proteins | 2016 |
Effect of lysine modification on the stability and cellular binding of human amyloidogenic light chains.
Topics: Amino Acid Sequence; Amyloidosis; Bence Jones Protein; Biotinylation; Cell Line; Cells, Cultured; Chromatography, Liquid; Circular Dichroism; Epithelial Cells; Fibroblasts; Humans; Immunoglobulin Light Chains; Immunoglobulin Light-chain Amyloidosis; Lysine; Male; Mass Spectrometry; Microscopy, Fluorescence; Molecular Sequence Data; Multiple Myeloma; Protein Binding; Protein Stability; Protein Structure, Secondary; Sequence Homology, Amino Acid; Thermodynamics | 2011 |
NSD2 links dimethylation of histone H3 at lysine 36 to oncogenic programming.
Topics: Animals; Cell Transformation, Neoplastic; Chromatin; Gene Expression Profiling; Gene Expression Regulation; Genome-Wide Association Study; Histone-Lysine N-Methyltransferase; Histones; Humans; Lysine; Methylation; Mice; Mice, SCID; Multiple Myeloma; Recombinant Proteins; Repressor Proteins; Signal Transduction; Transcription, Genetic; Translocation, Genetic; Xenograft Model Antitumor Assays | 2011 |
Triptolide induces cell-cycle arrest and apoptosis of human multiple myeloma cells in vitro via altering expression of histone demethylase LSD1 and JMJD2B.
Topics: Animals; Antineoplastic Agents, Alkylating; Apoptosis; Cell Cycle Checkpoints; Cell Line, Tumor; Cell Proliferation; Diterpenes; DNA Methylation; Epoxy Compounds; Histone Demethylases; Histones; Humans; Jumonji Domain-Containing Histone Demethylases; Lysine; Multiple Myeloma; Phenanthrenes | 2012 |
The formation of myeloma protein by a mouse plasma cell tumor.
Topics: Animals; Lysine; Mice; Multiple Myeloma; Myeloma Proteins; Plasma Cells; Plasmacytoma | 1958 |
THE BIOSYNTHESIS OF A LABELLED BENCE-JONES-PROTEIN AND ITS GLOMERULAR PERMEABILITY IN THE NORMAL DOG.
Topics: Bence Jones Protein; Dogs; Geriatrics; Kidney; Kidney Diseases; Kidney Glomerulus; Lysine; Metabolism; Multiple Myeloma; Permeability; Research; Serum Albumin; Urine | 1963 |
A simple kinetic model for myeloma cell culture with consideration of lysine limitation.
Topics: Biochemistry; Bioreactors; Cell Culture Techniques; Cell Line, Tumor; Glucose; Glutamine; Humans; Kinetics; Lysine; Models, Chemical; Models, Statistical; Models, Theoretical; Multiple Myeloma; Time Factors | 2008 |
Obligatory hybridization of heterologous immunoglobulin light chains into covalently linked dimers.
Topics: Bence Jones Protein; Crystallization; Disulfides; Electrophoresis, Polyacrylamide Gel; Humans; Immunoglobulin Light Chains; Kinetics; Lysine; Multiple Myeloma; Protein Binding; Protein Conformation; Protein Multimerization; X-Ray Diffraction | 1980 |
Spectroscopic properties of light-chain derivatives of murine MOPC-315 immunoglobulin A.
Topics: Alkylation; Animals; Circular Dichroism; Dinitrobenzenes; Immunoglobulin A; Immunoglobulin Light Chains; Lysine; Macromolecular Substances; Mice; Multiple Myeloma; Neoplasms, Experimental; Oxidation-Reduction; Protein Conformation; Spectrum Analysis | 1981 |
Immune response to liposomal model membranes: restricted IgM and IgG anti-dinitrophenyl antibodies produced in guinea pigs.
Topics: Animals; Antibody Formation; Antibody Specificity; Antibody-Producing Cells; Dinitrophenols; Erythrocytes; Female; Guinea Pigs; Hemagglutination Tests; Hemolytic Plaque Technique; Immunoglobulin G; Immunoglobulin M; Isoelectric Focusing; Liposomes; Lysine; Multiple Myeloma; Myeloma Proteins; Ovalbumin; Plasmacytoma; Serum Albumin; Sheep | 1975 |
Alterations in isotypic and allotypic immunoglobulin antigens induced by chemical modification.
Topics: Amidines; Amino Acid Sequence; Antibodies; Antigen-Antibody Reactions; Antigens; Bence Jones Protein; Binding Sites; gamma-Globulins; Histocompatibility Testing; Humans; Immune Sera; Immunochemistry; Immunodiffusion; Immunogenetics; Immunoglobulins; Indicators and Reagents; Lysine; Multiple Myeloma; Neoplasm Proteins | 1971 |
The incidence of precipitating activity in monoclonal proteins.
Topics: Animals; Antigens; Ascaris; Chromatography; Dinitrophenols; gamma-Globulins; Humans; Immunodiffusion; Immunoelectrophoresis; Immunoglobulin A; Immunoglobulin M; Iodoacetates; Lysine; Mercaptoethanol; Multiple Myeloma; Peptides; Polysaccharides, Bacterial; Precipitins; Rabbits; Rheumatoid Factor; Serum Albumin, Bovine; Staphylococcus; Streptococcus; Waldenstrom Macroglobulinemia | 1971 |
Recovery of binding activity in reconstituted mouse myeloma proteins.
Topics: Animals; Binding Sites; Blood Proteins; Chromatography, Gel; Fluorescence; gamma-Globulins; Immunoelectrophoresis; Immunoglobulins; Lysine; Mice; Multiple Myeloma; Neoplasm Proteins; Neoplasm Transplantation; Neoplasms, Experimental; Nitrobenzenes; Spectrophotometry | 1971 |
Variability of immunoglobulins.
Topics: Amino Acid Sequence; Animals; Antibody-Producing Cells; Autoradiography; Biological Evolution; Chromosome Aberrations; Clone Cells; Culture Techniques; Epitopes; Genes; Genetic Variation; Humans; Hybrid Cells; Immunoglobulins; Isoelectric Focusing; Lysine; Mice; Molecular Conformation; Multiple Myeloma; Mutation; Myeloma Proteins; Rats; Species Specificity | 1974 |
Markers of the variable and constant region of human lambda immunoglobulin chains.
Topics: Alleles; Amino Acid Sequence; Antigens; Arginine; Bence Jones Protein; Blood Group Antigens; Epitopes; Formates; Genes; Genetic Code; Germ Cells; Humans; Immune Sera; Immunodiffusion; Immunoglobulin G; Immunoglobulins; Lysine; Multiple Myeloma; Peptides; Trypsin; Waldenstrom Macroglobulinemia | 1970 |
Effect of chemical modification of lysine residues on the conformation of human immunoglobulin G.
Topics: Anhydrides; Animals; Carbamates; Chemical Phenomena; Chemistry; Circular Dichroism; Goats; Humans; Immune Sera; Immunodiffusion; Immunoelectrophoresis; Immunoglobulin G; Immunoglobulins; Lysine; Maleates; Multiple Myeloma; Protein Conformation; Species Specificity; Spectrophotometry; Viscosity | 1972 |
Light-chain typing of immunoglobulins synthesized in vitro by means of immunoselection and autoradiography.
Topics: Animals; Antibody Formation; Autoradiography; Bence Jones Protein; Blood Protein Disorders; Bone Marrow; Carbon Isotopes; Culture Techniques; Diagnosis, Differential; Humans; Immune Sera; Immunoglobulin A; Immunoglobulin Fragments; Immunoglobulin M; Immunoglobulins; Isoleucine; Lymph Nodes; Lysine; Methods; Multiple Myeloma; Rabbits; Skin; Spleen; Swine; Waldenstrom Macroglobulinemia | 1973 |
Automatic monitoring of biochemical parameters in tissue culture. Studies on synchronously growing mouse myeloma cells.
Topics: Animals; Autoanalysis; Carbon Isotopes; Culture Techniques; DNA; Lysine; Mice; Mitosis; Multiple Myeloma; Myeloma Proteins; Neoplasms, Experimental; RNA; Thymidine; Tritium; Uridine | 1972 |
The secretion of a sialic acid-free immunoglobulin.
Topics: Animals; Autoradiography; Carbon Isotopes; Cells, Cultured; Immunoglobulin G; Immunoglobulins; Isoelectric Focusing; Lysine; Mice; Multiple Myeloma; Mutation; Neoplasms, Experimental; Neuraminic Acids; Neuraminidase; Tritium | 1973 |
Amino acid sequence of the (lambda) light chain of a human myeloma immunoglobulin (IgG New).
Topics: Alkylation; Amino Acid Sequence; Amino Acids; Chromatography, Gel; Chymotrypsin; Dansyl Compounds; Electrophoresis; Formates; Humans; Hydrogen-Ion Concentration; Immunoglobulin Fragments; Immunoglobulin G; Lysine; Multiple Myeloma; Myeloma Proteins; Oxidation-Reduction; Peptide Fragments; Serine; Thiocyanates; Tosyl Compounds; Trypsin; X-Ray Diffraction | 1974 |
2,4-dinitrophenyl-hapten specific hemolytic plaque-in-gel formation by mouse myeloma (MOPC-315) cells.
Topics: Animals; Antibody Formation; Antigen-Antibody Reactions; Cell Line; Complement System Proteins; Dinitrophenols; Erythrocytes; Haptens; Hemagglutination Tests; Hemolytic Plaque Technique; Immune Sera; Immunoglobulin G; Lysine; Mice; Multiple Myeloma; Serum Albumin, Bovine | 1970 |
Human M-proteins with antibody activity for nitrophenyl ligands.
Topics: Aminocaproates; Antigen-Antibody Reactions; Bence Jones Protein; Blood Proteins; Dinitrophenols; Haptens; Humans; Immunodiffusion; Immunoelectrophoresis; Lysine; Multiple Myeloma; Tritium | 1970 |
Site-directed cross-linking: a new approach to mapping antibody combining sites.
Topics: Animals; Ascitic Fluid; Binding Sites; Boron Compounds; Chemical Phenomena; Chemistry; Chromatography, Gel; Diazonium Compounds; Electrophoresis, Disc; Fluorine; Immunoglobulin A; Immunoglobulin G; Lysine; Methods; Mice; Molecular Weight; Multiple Myeloma; Neoplasms, Experimental; Nitrobenzenes; Oxidation-Reduction; Protein Binding; Spectrophotometry; Sulfites; Sulfones; Tritium; Trypsin; Tyrosine | 1971 |
An analysis of the sequences of the variable regions of Bence Jones proteins and myeloma light chains and their implications for antibody complementarity.
Topics: Alanine; Amino Acid Sequence; Analysis of Variance; Animals; Antibodies; Antibody Specificity; Bence Jones Protein; Binding Sites; Genes; Glycine; Histidine; Humans; Immunoglobulin G; Immunoglobulin M; Leucine; Lysine; Mice; Models, Chemical; Multiple Myeloma; Rabbits; Species Specificity; Valine | 1970 |
Occurrence of L-lysine dehydrogenase (LyDH) in human serum in normal and some pathological states.
Topics: Adolescent; Adult; Amino Acid Oxidoreductases; Breast Neoplasms; Female; Heart Diseases; Heart Failure; Humans; Kidney Neoplasms; Leukemia, Lymphoid; Lung Neoplasms; Lymphoma; Lymphoma, Non-Hodgkin; Lysine; Male; Middle Aged; Multiple Myeloma; Myocardial Infarction; Neoplasms; Prostatic Neoplasms; Urogenital Neoplasms | 1967 |