Compounds > lysine
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lysine and Invasiveness, Neoplasm

lysine has been researched along with Invasiveness, Neoplasm in 65 studies

Research

Studies (65)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's15 (23.08)29.6817
2010's33 (50.77)24.3611
2020's17 (26.15)2.80

Authors

AuthorsStudies
Gao, W; Yao, J; Zhang, T1
Feng, T; Gu, R; Guo, Y; Li, K; Li, Q; Li, S; Lin, P; Ou, D; Yuan, H; Zhang, J; Zhao, G1
Ji, T; Liu, A; Mao, X; Weng, Y1
Li, B; Li, J; Li, N; Wen, S; Yang, J; Zhan, X1
Diao, H; Hao, N; Koropatnick, J; Liu, Q; Maleki Vareki, S; Min, J; Min, W; Raphael, J; Sang, Y; Wang, Z; Xiong, J; Xu, D; Zhang, Y; Zheng, X1
Ge, L; Huang, X; Sang, K; Yi, T; Zhou, J; Zhou, X1
Chen, W; Du, W; He, Y; Liu, N; Liu, X; Yang, Y; Zhang, Y1
Badodi, S; Barnes, MR; Brandner, S; Ceric, D; Cognolato, E; Gemma, C; Guglielmi, L; Marino, S; Millner, TO; Pomella, N; Ricci, B; Zhang, X; Zhang, Y1
Chen, Y; He, QM; He, SW; Hong, XH; Lei, Y; Li, JY; Li, YQ; Liang, YL; Liu, N; Luo, WJ; Ma, J; Tang, LL; Wang, YQ; Yang, XJ; Zhang, PP; Zhao, Y1
Wang, L; Wei, C; Zhang, H; Zhao, X1
Cai, Y; Chen, L; Chen, Y; Chen, Z; Feng, Y; Fu, Y; Huang, H; Huang, Y; Liu, R; Zhang, Y1
Huang, T; Jiang, G; Lyu, L; Xiang, W; Yuan, J; Zhang, C; Zheng, F1
An, N; Chen, XJ1
Han, X; Liang, S; Wei, J; Xiang, X; Yang, H; Yu, J; Zhang, H1
Lin, L; Liu, W; Luan, R; Song, H; Sun, N; Wang, C; Wang, M; Wang, S; Wei, S; Wu, Y; Yang, F; Zeng, K; Zhao, Y; Zhou, B; Zou, R1
Czogalla, B; Han, N; Hester, A; Heublein, S; Jeschke, U; Kuhn, C; Mahner, S; Mayr, D; Rottmann, M; Schmoeckel, E; Trillsch, F1
Huang, P; Li, W; Lin, L; Peng, Y; Xu, J; Yan, Y; Ye, H; Zhang, H; Zhang, R; Zheng, Z1
Chen, L; Deng, X; Gao, F; Li, B; Li, L; Li, X; Liang, T; Pan, Y; Ren, Y; Wang, J; Yang, D; Yang, Y; Zhai, S; Zhang, S; Zhang, X; Zhao, J; Zheng, Y; Zhou, P1
Chau, LY; Chiang, MT; Hsu, FF; Lee, WH; Li, FA; Yeh, CT1
Dai, B; Guan, F; Hu, Z; Huang, H; Mao, B; Su, H; Xiao, Z; Zhu, G1
Han, L; Lin, Y; Ma, D; Ma, X; Qin, Z; Qiu, Y; Sun, C; Sun, Y; You, Y; Zhao, Y; Zhu, L1
Bi, J; Cai, Q; Chen, C; Dong, W; He, W; Huang, J; Jiang, N; Li, H; Lin, T; Liu, H; Su, F; Wang, B; Zhang, B; Zhao, Y; Zhong, G1
Hayakawa, Y; Iwakami, Y; Watanabe, K; Yokoyama, S1
Chen, Z; Cheng, G; Du, P; Hu, K; Shen, X; Xu, L; Zhuang, Z1
Cao, W; Chen, HY; Cui, Y; Du, W; Fang, JY; Han, ZG; Hong, J; Lin, YW; Ren, LL; Shen, N; Sun, DF; Sun, TT; Wang, JL; Wang, YC; Wang, ZH; Weng, YR; Xiong, H; Xu, J; Yu, YN; Zou, W1
Hieda, M; Higashi, S; Kimura, H; Matsumoto, A; Matsuura, N; Matsuura, S; Mori, M; Nishioka, Y; Yamamoto, H; Yokoyama, Y1
Evers, BM; Huang, C; Kutys, ML; Li, X; Morris, AJ; Rychahou, P; Sunkara, M; Wu, Z; Zhou, Q; Zhu, H1
Hu, D; Ji, J; Tian, C; Zhang, L1
Aburatani, H; Fukayama, M; Hayashi, A; Ishikawa, S; Kimura, H; Kokudo, N; Morikawa, T; Nagae, G; Nishi, A; Sakamoto, Y; Shibahara, J; Yamauchi, N1
Chen, CK; Chen, MW; Hsiao, M; Hua, KT; Jan, YH; Jeng, YM; Ko, CH; Kuo, ML; Sung, PL; Wang, MY; Wei, LH; Yen, ML1
Hu, Z; Liu, Y; Qiu, J; Xiong, Z; Zheng, J; Zhu, Z1
Chen, Y; Huang, K; Li, J; Liang, J; Lin, Z; Qian, C; Wu, W; Zeng, L; Zhang, Q1
Biffoni, M; Cappellari, M; De Maria, R; Grande, S; Guidoni, L; Luciani, AM; Pallini, R; Palma, A; Ricci-Vitiani, L; Rosi, A; Runci, D; Viti, V1
Gudey, SK; Heldin, CH; Landström, M; Sundar, R1
Gan, YH; Jia, LF; Meng, Z1
Agnarsson, BA; Aittomäki, K; Andrulis, IL; Anton-Culver, H; Antoniou, AC; Bandera, EV; Banerjee, S; Barile, M; Barrowdale, D; Beckman, MW; Beeghly-Fadiel, A; Benitez, J; Berchuck, A; Bjorge, L; Blomqvist, C; Bogdanova, NV; Bojesen, SE; Bolla, MK; Borg, A; Borresen-Dale, AL; Brauch, H; Brenner, H; Broeks, A; Bruinsma, F; Brunet, J; Brüning, T; Burwinkel, B; Butterbach, K; Butzow, R; Buys, SS; Cai, H; Campbell, IG; Cannioto, R; Castillo, D; Chan, SB; Chang-Claude, J; Chenevix-Trench, G; Claes, KB; Collavoli, A; Cook, LS; Couch, FJ; Cox, A; Cramer, D; Cross, SS; Cunningham, JM; Czene, K; Daly, MB; Damiola, F; Darabi, H; Dennis, J; Devilee, P; Diez, O; Ding, YC; Doherty, JA; Domchek, SM; Dorfling, CM; Dörk, T; Dunning, AM; Easton, DF; Eccles, DM; Ellis, S; Eunjung, L; Fasching, PA; Feng, B; Figueroa, J; Flesch-Janys, D; Fletcher, O; Flyger, H; Foretova, L; Fostira, F; Friedman, E; Frost, D; Ganz, PA; Gao, YT; Garber, J; García-Closas, M; Gayther, S; Gerdes, AM; Giles, GG; Glasspool, R; Godwin, AK; Goldberg, MS; Goldgar, DE; González-Neira, A; Goode, EL; Goodman, MT; Greene, MH; Gronwald, J; Guénel, P; Hahnen, E; Haiman, CA; Hall, P; Hallberg, E; Hamann, U; Hansen, TV; Hart, SN; Healey, S; Heitz, F; Henderson, BE; Henriksson, K; Hildebrant, MA; Hogdall, C; Hogdall, E; Hogervorst, FB; Hopper, JL; Hosono, S; Hoya, Mde L; Hulick, PJ; Imyanitov, EN; Isaacs, C; Jakubowska, A; James, PA; Janavicius, R; Jensen, A; John, EM; Johnson, N; Jones, M; Kabisch, M; Karlan, BY; Khan, S; Kiemeney, LA; Kjaer, SK; Knight, JA; Konstantopoulou, I; Koppert, LB; Kosma, VM; Kristensen, V; Kupryjanczyk, J; Kwong, A; Laitman, Y; Lambrechts, D; Lazaro, C; Le, N; Lester, J; Levine, D; Li, J; Liang, D; Lindblom, A; Loud, JT; Lu, KH; Lubinski, J; Maerken, TV; Mai, PL; Mannermaa, A; Manoukian, S; Margolin, S; Marme, F; Massuger, LF; Matsuo, K; Maugard, C; Mazoyer, S; McGuffog, L; McNeish, I; Meeks, HD; Meindl, A; Menon, U; Michailidou, K; Milne, RL; Modugno, F; Moes-Sosnowska, J; Montagna, M; Monteiro, AN; Moysich, KB; Narod, S; Nathanson, KL; Ness, R; Neuhausen, SL; Nevanlinna, H; Neven, P; Nussbaum, RL; Offit, K; Öfverholm, A; Olah, E; Oliani, C; Olopade, OI; Olson, JE; Olson, SH; Osorio, A; Ouweland, AM; Park, SK; Pasini, BJ; Pearce, L; Pedersen, IS; Peissel, B; Peixoto, A; Pejovic, T; Pelttari, LM; Peterlongo, P; Pharoah, PD; Phelan, CM; Piedmonte, M; Poole, EM; Pylkäs, K; Radice, P; Ramus, SJ; Rantala, J; Rappaport-Feurhauser, C; Rennert, G; Riboli, E; Risch, H; Robson, M; Rossing, MA; Rudolph, A; Salvesen, HB; Sawyer, EJ; Schildkraut, J; Schmidt, MK; Schoemaker, MJ; Segura, PP; Senter, L; Shah, M; Shimelis, H; Siddiquil, N; Sieh, W; Simard, J; Singer, CF; Sinilnikova, OM; Slager, S; Song, H; Soucy, P; Southey, MC; Spurdle, AB; Stoppa-Lyonnet, D; Swerdlow, A; Teixeira, MR; Teo, SH; Terry, KL; Terry, MB; Tesoriero, A; Thomassen, M; Thompson, PJ; Tihomirova, L; Tischkowitz, M; Tollenaar, RA; Tomlinson, I; Torres, D; Truong, T; Tucker, K; Tung, N; Tworoger, SS; van Rensburg, EJ; Varon-Mateeva, R; Viel, A; Wang, Q; Wappenschmidt, B; Weitzel, JN; Wentzensen, N; Whittermore, AS; Winqvist, R; Woo, YL; Wu, A; Yoon, SY; Zheng, W1
Cai, Q; Casero, RA; Chen, H; Dou, Y; Jin, L; Jin, Y; Li, X; Liu, Y; Lu, J; Luo, H; Qiu, Y; Reisman, D; Seto, E; Shenoy, AK; Tang, M; Wu, L1
Giaccia, AJ1
Chan, CH; Frohman, MA; Lee, HJ; Li, CF; Powers, S; Ruan, D; Thompson, PA1
Beck, A; Glass, B; Kuperwasser, C; Ni, TK; Skibinski, A; Wronski, A; Zhou, W1
Chen, J; Lei, QY; Li, JT; Xu, YY; Yang, HB; Yao, CB; Yin, M; Zhang, M; Zhang, Y; Zhao, XN1
Atadja, P; Bhalla, K; Fiskus, W; Nechtman, J; Rao, R; Shen, J; Tang, Y; Yang, Y1
Barraclough, R; Fernig, DG; Ismail, TM; Rudland, PS; Terry, CJ; Wang, G1
Chernov, AV; Remacle, AG; Sounni, NE; Strongin, AY1
Bhanap, BA; Niedzwiecki, A; Rath, M; Roomi, MW; Roomi, NW1
Kalinovsky, T; Monterrey, JC; Niedzwiecki, A; Rath, M; Roomi, MW1
Chang, CC; Chen, ST; Hsieh, TH; Kuo, MY; Li, YJ; Lin, BR1
Bhanap, B; Niedzwiecki, A; Rath, M; Roomi, MW; Roomi, NW1
Peng, L; Seto, E1
Huang, C; Li, J; Liu, J; Wu, XR; Yu, J; Yu, Y; Zhang, D1
Al-Daccak, R; Alcaide-Loridan, C; Deshayes, F; Ghislin, S; Lauriol, J; Martins, I; Middendorp, S1
Gerard, B; Sanders, MA; Shekhar, MP; Tait, L; Visscher, DW1
Batra, J; Hockla, A; Mehner, C; Miller, E; Radisky, DC; Radisky, ES; Robinson, J1
Desaire, H; Finney, J; Go, EP; Lantz, M; Moon, H; Mure, M; Rebecchi, K; Xu, L1
Copié, V; Jaseja, M; Starkey, J1
Ivanov, V; Kalinovsky, T; Niedzwiecki, A; Rath, M; Roomi, MW6
Ivanov, V; Kalinovsky, T; Niedzwiecki, A; Rath, M; Roomi, MW; Roomi, N1
Ranson, M; Saunders, DN; Stillfried, GE1
Gawdi, G; Gonzalez-Gronow, M; Kaczowka, S; Pizzo, SV1
Bachmeier, BE; Friess, U; Nerlich, AG; Rohrbach, H; Schleicher, ED1

Reviews

2 review(s) available for lysine and Invasiveness, Neoplasm

ArticleYear
Deacetylation of nonhistone proteins by HDACs and the implications in cancer.
    Handbook of experimental pharmacology, 2011, Volume: 206

    Topics: Acetylation; Animals; Apoptosis; Autophagy; Cell Differentiation; DNA Damage; Histone Acetyltransferases; Histone Deacetylase Inhibitors; Humans; Lysine; Neoplasm Invasiveness; Neoplasms; Protein Processing, Post-Translational

2011
Dipeptidyl peptidase IV (DPP IV/CD26) is a cell-surface plasminogen receptor.
    Frontiers in bioscience : a journal and virtual library, 2008, Jan-01, Volume: 13

    Topics: Adenosine Deaminase; Binding Sites; Cell Line, Tumor; Cytosol; Dipeptidyl Peptidase 4; Humans; Hydrogen-Ion Concentration; Ligands; Lysine; Male; Neoplasm Invasiveness; Plasminogen; Prostatic Neoplasms; Receptors, Cell Surface; Receptors, Urokinase Plasminogen Activator; Sodium-Hydrogen Exchanger 3; Sodium-Hydrogen Exchangers

2008

Other Studies

63 other study(ies) available for lysine and Invasiveness, Neoplasm

ArticleYear
[Knockdown of lysine-specific demethylase 3A (KDM3A) inhibits the invasion and migration of MDA-MB-231 breast cancer cells and arrests the cell cycle in the G0/G1 phase].
    Xi bao yu fen zi mian yi xue za zhi = Chinese journal of cellular and molecular immunology, 2021, Volume: 37, Issue:9

    Topics: Breast Neoplasms; Cell Cycle; Cell Line, Tumor; Cell Movement; Cell Proliferation; Female; G1 Phase; Gene Expression Regulation, Neoplastic; Humans; Jumonji Domain-Containing Histone Demethylases; Lysine; Neoplasm Invasiveness

2021
Loss of TRIM31 promotes breast cancer progression through regulating K48- and K63-linked ubiquitination of p53.
    Cell death & disease, 2021, 10-14, Volume: 12, Issue:10

    Topics: Animals; Breast Neoplasms; Carcinogenesis; Cell Line, Tumor; Cell Movement; Cell Proliferation; Disease Progression; Down-Regulation; Female; Gene Expression Regulation, Neoplastic; Humans; Lysine; Mice, Inbred C57BL; Mice, Nude; Middle Aged; Neoplasm Invasiveness; Neoplasm Metastasis; Protein Binding; Protein Domains; Protein Stability; Proto-Oncogene Proteins c-mdm2; RNA, Messenger; Treatment Outcome; Tripartite Motif Proteins; Tumor Suppressor Protein p53; Ubiquitin-Protein Ligases; Ubiquitination

2021
ELK4-mediated lncRNA SNHG22 promotes gastric cancer progression through interacting with EZH2 and regulating miR-200c-3p/Notch1 axis.
    Cell death & disease, 2021, 10-18, Volume: 12, Issue:11

    Topics: Animals; Base Sequence; Binding Sites; Cell Line, Tumor; Cell Proliferation; Disease Progression; Enhancer of Zeste Homolog 2 Protein; ets-Domain Protein Elk-4; Female; Gene Expression Regulation, Neoplastic; Gene Silencing; Genes, Tumor Suppressor; Histones; Humans; Lysine; Methylation; Mice, Inbred BALB C; Mice, Nude; MicroRNAs; Neoplasm Invasiveness; Promoter Regions, Genetic; Protein Binding; Receptor, Notch1; RNA, Long Noncoding; Stomach Neoplasms; Up-Regulation

2021
Quantitative Acetylomics Revealed Acetylation-Mediated Molecular Pathway Network Changes in Human Nonfunctional Pituitary Neuroendocrine Tumors.
    Frontiers in endocrinology, 2021, Volume: 12

    Topics: Acetylation; Amino Acids; Glycolysis; Humans; Hydrolysis; Lysine; Metabolic Networks and Pathways; Neoplasm Invasiveness; Neuroendocrine Tumors; Phosphoglycerate Kinase; Pituitary Neoplasms; Protein Processing, Post-Translational; Ubiquitination

2021
TdIF1-LSD1 Axis Regulates Epithelial-Mesenchymal Transition and Metastasis via Histone Demethylation of E-Cadherin Promoter in Lung Cancer.
    International journal of molecular sciences, 2021, 12-27, Volume: 23, Issue:1

    Topics: Animals; Cadherins; Carcinogenesis; Cell Line, Tumor; Cell Movement; Demethylation; DNA-Binding Proteins; Down-Regulation; Epithelial-Mesenchymal Transition; Gene Expression Regulation, Neoplastic; Gene Knockdown Techniques; Histone Demethylases; Histones; Lung Neoplasms; Lysine; Methylation; Mice, Inbred BALB C; Mice, Nude; Neoplasm Invasiveness; Neoplasm Metastasis; Promoter Regions, Genetic; Protein Binding; Transcription Factors

2021
Activation of lncRNA lnc-SLC4A1-1 induced by H3K27 acetylation promotes the development of breast cancer via activating CXCL8 and NF-kB pathway.
    Artificial cells, nanomedicine, and biotechnology, 2019, Volume: 47, Issue:1

    Topics: Acetylation; Adult; Anion Exchange Protein 1, Erythrocyte; Apoptosis; Breast Neoplasms; Carcinogenesis; Cell Line, Tumor; Cell Movement; Cell Proliferation; Female; Gene Expression Regulation, Neoplastic; Histones; Humans; Interleukin-8; Lysine; Middle Aged; Neoplasm Invasiveness; NF-kappa B; RNA, Long Noncoding; Signal Transduction; Transcriptional Activation; Up-Regulation

2019
PLOD2 promotes aerobic glycolysis and cell progression in colorectal cancer by upregulating HK2.
    Biochemistry and cell biology = Biochimie et biologie cellulaire, 2020, Volume: 98, Issue:3

    Topics: Aerobiosis; Aged; Caco-2 Cells; Cell Line, Tumor; Cell Movement; Cell Proliferation; Collagen; Colorectal Neoplasms; Disease Progression; Female; Gene Expression Regulation, Neoplastic; Glucose; Glycolysis; Hexokinase; HT29 Cells; Humans; Lysine; Male; Middle Aged; Neoplasm Invasiveness; Procollagen-Lysine, 2-Oxoglutarate 5-Dioxygenase; RNA, Messenger; Signal Transduction; STAT3 Transcription Factor; Up-Regulation

2020
Polycomb-mediated repression of EphrinA5 promotes growth and invasion of glioblastoma.
    Oncogene, 2020, Volume: 39, Issue:12

    Topics: Animals; Antihypertensive Agents; Cell Proliferation; Doxazosin; Drug Delivery Systems; Ephrin-A5; Epigenesis, Genetic; Gene Expression Regulation, Neoplastic; Glioblastoma; Histones; Humans; Lysine; Mice; Mice, Transgenic; Neoplasm Invasiveness; Neural Stem Cells; Neurogenesis; Polycomb Repressive Complex 1; Tumor Cells, Cultured

2020
Hypermethylation of
    Cells, 2020, 02-27, Volume: 9, Issue:3

    Topics: Animals; Cell Line, Tumor; Cell Movement; Cortactin; DNA Methylation; Down-Regulation; Female; Gene Expression Regulation, Neoplastic; HEK293 Cells; Humans; Lysine; Mice, Inbred BALB C; Mice, Nude; Nasopharyngeal Carcinoma; Neoplasm Invasiveness; Neoplasm Metastasis; Promoter Regions, Genetic; Protein Binding; Proteolysis; Ubiquitin Thiolesterase; Ubiquitination

2020
TRIP suppresses cell proliferation and invasion in choroidal melanoma via promoting the proteasomal degradation of Twist1.
    FEBS letters, 2020, Volume: 594, Issue:19

    Topics: Cell Line, Tumor; Cell Movement; Cell Proliferation; Choroid; Epithelial-Mesenchymal Transition; Gene Expression Regulation, Neoplastic; HEK293 Cells; Humans; Lysine; Melanoma; Neoplasm Invasiveness; Polyubiquitin; Prognosis; Proteasome Endopeptidase Complex; Proteolysis; Twist-Related Protein 1; Ubiquitin-Protein Ligases; Ubiquitination; Up-Regulation

2020
Acetylation-mediated degradation of HSD17B4 regulates the progression of prostate cancer.
    Aging, 2020, 07-17, Volume: 12, Issue:14

    Topics: Acetylation; Animals; Cell Line, Tumor; Cell Movement; Cell Proliferation; CREB-Binding Protein; Disease Progression; Gene Expression Regulation, Neoplastic; Gene Knockdown Techniques; Humans; Lysine; Male; Mice; Mice, Knockout; Neoplasm Invasiveness; Peroxisomal Multifunctional Protein-2; Prostatic Neoplasms; Sirtuin 3; Testosterone; Xenograft Model Antitumor Assays

2020
The long non-coding RNA SNHG1 promotes bladder cancer progression by interacting with miR-143-3p and EZH2.
    Journal of cellular and molecular medicine, 2020, Volume: 24, Issue:20

    Topics: Animals; Antigens, CD; Base Sequence; Cadherins; Carcinogenesis; Cell Line, Tumor; Cell Movement; Cell Nucleus; Cell Proliferation; Cytoplasm; Disease Progression; Enhancer of Zeste Homolog 2 Protein; Epigenesis, Genetic; Female; Gene Expression Regulation, Neoplastic; Gene Silencing; Hexokinase; Histones; Humans; Lysine; Male; Methylation; Mice, Inbred BALB C; Mice, Nude; MicroRNAs; Middle Aged; Models, Biological; Neoplasm Invasiveness; Neoplasm Metastasis; RNA, Long Noncoding; Transcription, Genetic; Up-Regulation; Urinary Bladder Neoplasms

2020
Long noncoding RNA ATB promotes ovarian cancer tumorigenesis by mediating histone H3 lysine 27 trimethylation through binding to EZH2.
    Journal of cellular and molecular medicine, 2021, Volume: 25, Issue:1

    Topics: Carcinogenesis; Cell Line, Tumor; Cell Movement; Cell Proliferation; Enhancer of Zeste Homolog 2 Protein; Female; Gene Expression Regulation, Neoplastic; Gene Silencing; Histones; Humans; Lysine; Methylation; Models, Biological; Neoplasm Invasiveness; Ovarian Neoplasms; Protein Binding; RNA, Long Noncoding; Treatment Outcome

2021
p300-Catalyzed Lysine Crotonylation Promotes the Proliferation, Invasion, and Migration of HeLa Cells via Heterogeneous Nuclear Ribonucleoprotein A1.
    Analytical cellular pathology (Amsterdam), 2020, Volume: 2020

    Topics: Biocatalysis; Cell Movement; Cell Proliferation; E1A-Associated p300 Protein; Female; HeLa Cells; Heterogeneous Nuclear Ribonucleoprotein A1; Humans; Lysine; Neoplasm Invasiveness; Protein Processing, Post-Translational

2020
MOF upregulates the estrogen receptor α signaling pathway by its acetylase activity in hepatocellular carcinoma.
    Cancer science, 2021, Volume: 112, Issue:5

    Topics: Acetylation; Acetylesterase; Animals; Antibodies; Carcinoma, Hepatocellular; Cell Movement; Cell Proliferation; Databases, Genetic; Down-Regulation; Estrogen Receptor alpha; Female; Heterografts; Histone Acetyltransferases; Histones; Humans; Kaplan-Meier Estimate; Liver Neoplasms; Lysine; Male; Mice; Middle Aged; Neoplasm Invasiveness; Signal Transduction; Transcriptional Activation; Ubiquitination; Up-Regulation

2021
The G-Protein-Coupled Estrogen Receptor (GPER) Regulates Trimethylation of Histone H3 at Lysine 4 and Represses Migration and Proliferation of Ovarian Cancer Cells In Vitro.
    Cells, 2021, 03-11, Volume: 10, Issue:3

    Topics: Antineoplastic Agents; Cell Line, Tumor; Cell Movement; Cell Proliferation; DNA Methylation; Epigenesis, Genetic; Extracellular Signal-Regulated MAP Kinases; Female; Gene Expression Regulation, Neoplastic; Histones; Humans; Lysine; Neoplasm Invasiveness; Ovarian Neoplasms; Phosphorylation; Receptors, Estrogen; Receptors, G-Protein-Coupled; Signal Transduction

2021
SMYD3 promotes hepatocellular carcinoma progression by methylating S1PR1 promoters.
    Cell death & disease, 2021, 07-23, Volume: 12, Issue:8

    Topics: Apoptosis; Base Sequence; Carcinoma, Hepatocellular; Cell Cycle; Cell Line, Tumor; Cell Movement; Cell Proliferation; Disease Progression; Gene Expression Regulation, Neoplastic; HEK293 Cells; Histone-Lysine N-Methyltransferase; Histones; Humans; Liver Neoplasms; Lysine; Methylation; Neoplasm Invasiveness; Promoter Regions, Genetic; RNA, Messenger; Signal Transduction; Sphingosine-1-Phosphate Receptors; Tumor Stem Cell Assay

2021
Histone demethylase KDM4A plays an oncogenic role in nasopharyngeal carcinoma by promoting cell migration and invasion.
    Experimental & molecular medicine, 2021, Volume: 53, Issue:8

    Topics: Adult; Aged; Animals; Apoptosis; Carcinogenesis; Cell Line, Tumor; Cell Movement; Cell Proliferation; Female; Gene Expression Regulation, Neoplastic; Gene Silencing; Histones; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; Jumonji Domain-Containing Histone Demethylases; Lysine; Male; Methylation; Mice, Nude; Middle Aged; Nasopharyngeal Carcinoma; Neoplasm Invasiveness; Signal Transduction; TOR Serine-Threonine Kinases; Transcription Factors; Up-Regulation; Young Adult

2021
Acetylation is essential for nuclear heme oxygenase-1-enhanced tumor growth and invasiveness.
    Oncogene, 2017, 12-07, Volume: 36, Issue:49

    Topics: Acetylation; Animals; Cell Line, Tumor; Cell Nucleus; Cell Proliferation; Female; HEK293 Cells; HeLa Cells; Heme Oxygenase-1; Humans; Lysine; Mice, Inbred BALB C; Mice, Nude; Mutation; Neoplasm Invasiveness; Neoplasms; Transplantation, Heterologous; Tumor Burden

2017
Histone demethylase KDM5A inhibits glioma cells migration and invasion by down regulating ZEB1.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2018, Volume: 99

    Topics: Biocatalysis; Biomarkers, Tumor; Cell Line, Tumor; Cell Movement; Down-Regulation; Epithelial-Mesenchymal Transition; Gene Expression Regulation, Neoplastic; Gene Knockdown Techniques; Glioma; Histones; Humans; Lysine; Methylation; Neoplasm Invasiveness; Neoplasm Metastasis; Promoter Regions, Genetic; Retinoblastoma-Binding Protein 2; Zinc Finger E-box-Binding Homeobox 1

2018
TRIM50 suppressed hepatocarcinoma progression through directly targeting SNAIL for ubiquitous degradation.
    Cell death & disease, 2018, 05-22, Volume: 9, Issue:6

    Topics: Anoikis; Antineoplastic Agents; Carcinoma, Hepatocellular; Cell Line, Tumor; Cell Proliferation; Disease Progression; Down-Regulation; Epithelial-Mesenchymal Transition; Female; Gene Expression Regulation, Neoplastic; Humans; Liver Neoplasms; Lysine; Male; Middle Aged; Models, Biological; Neoplasm Invasiveness; Polyubiquitin; Proteolysis; Snail Family Transcription Factors; Tripartite Motif Proteins; Tumor Stem Cell Assay; Ubiquitin-Protein Ligases; Ubiquitination

2018
LNMAT1 promotes lymphatic metastasis of bladder cancer via CCL2 dependent macrophage recruitment.
    Nature communications, 2018, 09-20, Volume: 9, Issue:1

    Topics: Animals; Base Sequence; Cell Line, Tumor; Chemokine CCL2; DNA, Neoplasm; Gene Expression Regulation, Neoplastic; Histones; Humans; Lymphangiogenesis; Lymphatic Metastasis; Lysine; Macrophages; Methylation; Mice; Neoplasm Invasiveness; Prognosis; Promoter Regions, Genetic; Ribonucleoproteins; RNA, Long Noncoding; RNA, Neoplasm; Up-Regulation; Urinary Bladder Neoplasms

2018
STAM-binding protein regulates melanoma metastasis through SLUG stabilization.
    Biochemical and biophysical research communications, 2018, 12-09, Volume: 507, Issue:1-4

    Topics: Animals; Cell Line, Tumor; Cell Survival; Endosomal Sorting Complexes Required for Transport; Female; Humans; Lysine; Melanoma; Mice; Neoplasm Invasiveness; Neoplasm Metastasis; Protein Stability; Snail Family Transcription Factors; Ubiquitin Thiolesterase; Ubiquitination

2018
KDM5D inhibit epithelial-mesenchymal transition of gastric cancer through demethylation in the promoter of Cul4A in male.
    Journal of cellular biochemistry, 2019, Volume: 120, Issue:8

    Topics: Animals; Cell Movement; Cullin Proteins; Demethylation; Down-Regulation; Epithelial-Mesenchymal Transition; Gene Expression Regulation, Neoplastic; HEK293 Cells; Histone Demethylases; Histones; Humans; Lysine; Male; Mice, Nude; Minor Histocompatibility Antigens; Neoplasm Invasiveness; Neoplasm Metastasis; Promoter Regions, Genetic; Stomach Neoplasms

2019
Role of STAT3 and vitamin D receptor in EZH2-mediated invasion of human colorectal cancer.
    The Journal of pathology, 2013, Volume: 230, Issue:3

    Topics: Animals; Base Sequence; Cell Line, Tumor; Colorectal Neoplasms; Down-Regulation; Enhancer of Zeste Homolog 2 Protein; Gene Expression Regulation, Neoplastic; Histone Methyltransferases; Histone-Lysine N-Methyltransferase; Histones; Humans; Lysine; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Methylation; Mice; Mice, Inbred BALB C; Mice, Nude; Molecular Sequence Data; Neoplasm Invasiveness; Polycomb Repressive Complex 2; Receptors, Calcitriol; Recombinant Fusion Proteins; RNA Interference; Signal Transduction; STAT3 Transcription Factor

2013
Cancer-associated upregulation of histone H3 lysine 9 trimethylation promotes cell motility in vitro and drives tumor formation in vivo.
    Cancer science, 2013, Volume: 104, Issue:7

    Topics: Aged; Aged, 80 and over; Animals; Breast Neoplasms; Carcinogenesis; Cell Line, Tumor; Cell Movement; Colorectal Neoplasms; Epigenesis, Genetic; Female; Histone Methyltransferases; Histone-Lysine N-Methyltransferase; Histones; Humans; Lymph Nodes; Lymphatic Metastasis; Lysine; Male; Methylation; Methyltransferases; Mice; Mice, Inbred BALB C; Mice, Nude; Middle Aged; Neoplasm Invasiveness; Repressor Proteins; Up-Regulation

2013
Ubiquitylation of phosphatidylinositol 4-phosphate 5-kinase type I γ by HECTD1 regulates focal adhesion dynamics and cell migration.
    Journal of cell science, 2013, Jun-15, Volume: 126, Issue:Pt 12

    Topics: Animals; Cell Line; Cell Movement; CHO Cells; Cricetinae; Cricetulus; Focal Adhesions; HEK293 Cells; Humans; Integrin beta Chains; Lysine; Neoplasm Invasiveness; Neoplasm Metastasis; Phosphatidylinositol 4,5-Diphosphate; Phosphotransferases (Alcohol Group Acceptor); Talin; Ubiquitin-Protein Ligases; Ubiquitination

2013
Ghrelin induces gastric cancer cell proliferation, migration, and invasion through GHS-R/NF-κB signaling pathway.
    Molecular and cellular biochemistry, 2013, Volume: 382, Issue:1-2

    Topics: Animals; Cell Cycle; Cell Line, Tumor; Cell Movement; Cell Proliferation; Gene Expression Regulation, Neoplastic; Ghrelin; Humans; Lysine; Matrix Metalloproteinase 2; Mice; Neoplasm Invasiveness; NF-kappa B; Receptors, Ghrelin; RNA, Messenger; Signal Transduction; Stomach Neoplasms

2013
Concurrent activation of acetylation and tri-methylation of H3K27 in a subset of hepatocellular carcinoma with aggressive behavior.
    PloS one, 2014, Volume: 9, Issue:3

    Topics: Acetylation; beta Catenin; Carcinoma, Hepatocellular; Fluorescent Antibody Technique; Hepatectomy; Histones; Humans; Kaplan-Meier Estimate; Liver Neoplasms; Lysine; Methylation; Multivariate Analysis; Neoplasm Invasiveness; Treatment Outcome; Tumor Suppressor Protein p53

2014
The H3K9 methyltransferase G9a is a marker of aggressive ovarian cancer that promotes peritoneal metastasis.
    Molecular cancer, 2014, Aug-12, Volume: 13

    Topics: Animals; Anoikis; Biomarkers, Tumor; Cell Adhesion; Cell Line, Tumor; Cell Movement; Disease Progression; Female; Gene Expression Regulation, Neoplastic; Gene Knockdown Techniques; Histocompatibility Antigens; Histone-Lysine N-Methyltransferase; Histones; Humans; Lysine; Mice, Inbred NOD; Mice, SCID; Multivariate Analysis; Neoplasm Invasiveness; Ovarian Neoplasms; Peritoneal Neoplasms; Prognosis; Signal Transduction

2014
Knockdown of protein tyrosine phosphatase receptor U inhibits growth and motility of gastric cancer cells.
    International journal of clinical and experimental pathology, 2014, Volume: 7, Issue:9

    Topics: beta Catenin; Cell Adhesion; Cell Line, Tumor; Cell Movement; Cell Proliferation; Gene Expression Regulation, Neoplastic; Gene Knockdown Techniques; Histones; Humans; Lysine; Methylation; Neoplasm Invasiveness; Phosphorylation; Receptor-Like Protein Tyrosine Phosphatases, Class 2; RNA Interference; Signal Transduction; Stomach Neoplasms; Time Factors; Transcription, Genetic; Transfection; Tyrosine

2014
Effective suppression of the Kirsten rat sarcoma viral oncogene in pancreatic tumor cells via targeted small interfering RNA delivery using nanoparticles.
    Pancreas, 2015, Volume: 44, Issue:2

    Topics: Animals; Cell Movement; Cell Proliferation; Female; Gene Expression Regulation, Neoplastic; Gene Knockdown Techniques; Genetic Therapy; Humans; Hyaluronan Receptors; Lysine; Mice, Inbred BALB C; Mice, Nude; Micelles; Nanomedicine; Nanoparticles; Neoplasm Invasiveness; Pancreatic Neoplasms; Polyethylene Glycols; Proto-Oncogene Proteins; Proto-Oncogene Proteins p21(ras); ras Proteins; RNA Interference; RNA, Small Interfering; Single-Chain Antibodies; Time Factors; Transfection; Tumor Burden; U937 Cells; Vascular Endothelial Growth Factor A; Xenograft Model Antitumor Assays

2015
(1) H NMR spectroscopy of glioblastoma stem-like cells identifies alpha-aminoadipate as a marker of tumor aggressiveness.
    NMR in biomedicine, 2015, Volume: 28, Issue:3

    Topics: 2-Aminoadipic Acid; Adult; Aged; Biomarkers, Tumor; Brain Neoplasms; Cell Survival; Female; Glioblastoma; Humans; Kaplan-Meier Estimate; Lysine; Male; Metabolic Networks and Pathways; Mitochondria; Multivariate Analysis; Neoplasm Invasiveness; Neoplastic Stem Cells; Proton Magnetic Resonance Spectroscopy; Signal Processing, Computer-Assisted

2015
TRAF6 promotes TGFβ-induced invasion and cell-cycle regulation via Lys63-linked polyubiquitination of Lys178 in TGFβ type I receptor.
    Cell cycle (Georgetown, Tex.), 2015, Volume: 14, Issue:4

    Topics: Cell Cycle; Cell Line, Tumor; Flow Cytometry; Fluorescent Antibody Technique; Humans; Immunoblotting; Immunoprecipitation; Lysine; Male; Microarray Analysis; Neoplasm Invasiveness; Prostatic Neoplasms; Protein Serine-Threonine Kinases; Real-Time Polymerase Chain Reaction; Receptor, Transforming Growth Factor-beta Type I; Receptors, Transforming Growth Factor beta; Statistics, Nonparametric; TNF Receptor-Associated Factor 6; Ubiquitination

2015
PTEN activation through K163 acetylation by inhibiting HDAC6 contributes to tumour inhibition.
    Oncogene, 2016, 05-05, Volume: 35, Issue:18

    Topics: Acetylation; Animals; Cell Line, Tumor; Cell Membrane; Cell Movement; Cell Proliferation; Enzyme Activation; Gene Expression Regulation, Neoplastic; Histone Deacetylase 6; Histone Deacetylase Inhibitors; Histone Deacetylases; Humans; Hydroxamic Acids; Lysine; Mice; Neoplasm Invasiveness; Protein Transport; PTEN Phosphohydrolase; Vorinostat; Xenograft Model Antitumor Assays

2016
BRCA2 Polymorphic Stop Codon K3326X and the Risk of Breast, Prostate, and Ovarian Cancers.
    Journal of the National Cancer Institute, 2016, Volume: 108, Issue:2

    Topics: Adult; Aged; BRCA2 Protein; Breast Neoplasms; Codon, Terminator; Female; Genetic Predisposition to Disease; Heterozygote; Humans; Logistic Models; Lysine; Male; Middle Aged; Neoplasm Invasiveness; Odds Ratio; Ovarian Neoplasms; Polymorphism, Single Nucleotide; Prostatic Neoplasms; Risk Assessment; Risk Factors

2016
MOF Acetylates the Histone Demethylase LSD1 to Suppress Epithelial-to-Mesenchymal Transition.
    Cell reports, 2016, 06-21, Volume: 15, Issue:12

    Topics: Acetylation; Cadherins; Cell Line, Tumor; Disease Progression; Down-Regulation; Embryo, Mammalian; Epithelial Cells; Epithelial-Mesenchymal Transition; Fibroblasts; Gene Expression Regulation, Neoplastic; Histone Acetyltransferases; Histone Demethylases; Histones; Humans; Lysine; Methylation; Multiprotein Complexes; Mutation; Neoplasm Invasiveness; Neoplasm Metastasis; Nucleosomes

2016
A New Chromatin-Cytoskeleton Link in Cancer.
    Molecular cancer research : MCR, 2016, Volume: 14, Issue:12

    Topics: Chromatin; Cytoskeleton; Genomic Instability; Histone-Lysine N-Methyltransferase; Histones; Humans; Lysine; Methylation; Mutation; Neoplasm Invasiveness; Neoplasm Metastasis; Neoplasms; Tubulin

2016
The DNA Damage Transducer RNF8 Facilitates Cancer Chemoresistance and Progression through Twist Activation.
    Molecular cell, 2016, 09-15, Volume: 63, Issue:6

    Topics: Animals; Antineoplastic Agents; Breast Neoplasms; Cell Line, Tumor; Disease Progression; DNA Damage; DNA-Binding Proteins; Drug Resistance, Neoplasm; Epithelial-Mesenchymal Transition; Female; Gene Expression Regulation, Neoplastic; Genes, Reporter; Humans; Luciferases; Lysine; MCF-7 Cells; Mice, Nude; Neoplasm Invasiveness; Neoplasm Transplantation; Neoplastic Stem Cells; Nuclear Proteins; RNA, Small Interfering; Signal Transduction; Survival Analysis; Twist-Related Protein 1; Ubiquitin-Protein Ligases; Ubiquitination

2016
The SIRT2 Deacetylase Stabilizes Slug to Control Malignancy of Basal-like Breast Cancer.
    Cell reports, 2016, 10-25, Volume: 17, Issue:5

    Topics: Amino Acid Sequence; Animals; Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; Female; Gene Silencing; HEK293 Cells; Humans; Lysine; Mice, Inbred NOD; Mice, SCID; Neoplasm Invasiveness; Protein Binding; Protein Stability; Proteomics; Sirtuin 2; Snail Family Transcription Factors; Substrate Specificity

2016
Acetylation targets HSD17B4 for degradation via the CMA pathway in response to estrone.
    Autophagy, 2017, Mar-04, Volume: 13, Issue:3

    Topics: Acetylation; Autophagy; Breast Neoplasms; Cell Line, Tumor; Cell Movement; CREB-Binding Protein; Down-Regulation; Estrone; Female; Gene Expression Regulation, Neoplastic; HEK293 Cells; Humans; Lysine; Models, Biological; Mutation; Neoplasm Invasiveness; Peroxisomal Multifunctional Protein-2; Proteolysis; Sirtuin 3; Substrate Specificity

2017
Role of acetylation and extracellular location of heat shock protein 90alpha in tumor cell invasion.
    Cancer research, 2008, Jun-15, Volume: 68, Issue:12

    Topics: Acetylation; Adenosine Triphosphate; Benzoquinones; Breast Neoplasms; Cells, Cultured; Collagen; Drug Combinations; Histone Deacetylase 6; Histone Deacetylase Inhibitors; Histone Deacetylases; HSP90 Heat-Shock Proteins; Humans; Hydroxamic Acids; Immunoblotting; Immunoprecipitation; Indoles; Lactams, Macrocyclic; Laminin; Lysine; Matrix Metalloproteinase 2; Mutagenesis, Site-Directed; Neoplasm Invasiveness; p300-CBP Transcription Factors; Panobinostat; Protein Processing, Post-Translational; Proteoglycans; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization

2008
The basic C-terminal amino acids of calcium-binding protein S100A4 promote metastasis.
    Carcinogenesis, 2008, Volume: 29, Issue:12

    Topics: Amino Acid Sequence; Animals; Binding Sites; Blotting, Western; Cell Line, Tumor; Cell Movement; Humans; Lysine; Molecular Motor Proteins; Molecular Sequence Data; Mutagenesis, Site-Directed; Myosin Heavy Chains; Neoplasm Invasiveness; Neoplasm Metastasis; Polymerase Chain Reaction; Protein Binding; Rats; S100 Calcium-Binding Protein A4; S100 Proteins; Transfection

2008
Epigenetic control of the invasion-promoting MT1-MMP/MMP-2/TIMP-2 axis in cancer cells.
    The Journal of biological chemistry, 2009, May-08, Volume: 284, Issue:19

    Topics: Blotting, Western; Breast Neoplasms; Cell Movement; Chromatin; Chromatin Immunoprecipitation; CpG Islands; DNA Methylation; Epigenesis, Genetic; Fibrosarcoma; Glioblastoma; Histones; Humans; Immunoprecipitation; Lysine; Matrix Metalloproteinase 14; Matrix Metalloproteinase 2; Neoplasm Invasiveness; Promoter Regions, Genetic; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tissue Inhibitor of Metalloproteinase-2; Tumor Cells, Cultured

2009
Antineoplastic effects of nutrient mixture on raji and jurkat t cells: the two highly aggressive non Hodgkin's lymphoma cell lines.
    Experimental oncology, 2009, Volume: 31, Issue:3

    Topics: Antineoplastic Agents; Apoptosis; Ascorbic Acid; Burkitt Lymphoma; Cell Proliferation; Collagen; Drug Combinations; Humans; Laminin; Lymphoma, T-Cell; Lysine; Matrix Metalloproteinase 9; Neoplasm Invasiveness; Proline; Proteoglycans; Tea; Tumor Cells, Cultured

2009
Comparative effects of EGCG, green tea and a nutrient mixture on the patterns of MMP-2 and MMP-9 expression in cancer cell lines.
    Oncology reports, 2010, Volume: 24, Issue:3

    Topics: Antineoplastic Agents, Phytogenic; Ascorbic Acid; Camellia sinensis; Catechin; Cell Line, Tumor; Dose-Response Relationship, Drug; Humans; Lysine; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Matrix Metalloproteinase Inhibitors; Micronutrients; Neoplasm Invasiveness; Neoplasms; Plant Extracts; Proline; Protease Inhibitors; Tetradecanoylphorbol Acetate

2010
HDAC2 promotes cell migration/invasion abilities through HIF-1α stabilization in human oral squamous cell carcinoma.
    Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology, 2011, Volume: 40, Issue:7

    Topics: Animals; Carcinoma, Squamous Cell; Cell Line, Tumor; Cell Movement; Disease Progression; Female; Gene Expression Profiling; Gene Knockdown Techniques; Histone Deacetylase 2; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; Lymphatic Metastasis; Lysine; Mice; Mice, SCID; Mouth Neoplasms; Neoplasm Invasiveness; Neoplasm Transplantation; Protein Processing, Post-Translational; Protein Stability; Random Allocation; Ubiquitination; Von Hippel-Lindau Tumor Suppressor Protein

2011
In vivo and in vitro antitumor effects of nutrient mixture in murine leukemia cell line P-388.
    Experimental oncology, 2011, Volume: 33, Issue:2

    Topics: Animals; Antioxidants; Apoptosis; Ascorbic Acid; Camellia sinensis; Cell Line, Tumor; Cell Proliferation; Collagen; Drug Combinations; Food; Laminin; Leukemia; Lysine; Mice; Mice, Nude; Neoplasm Invasiveness; Plant Extracts; Proline; Proteoglycans

2011
RhoGDI SUMOylation at Lys-138 increases its binding activity to Rho GTPase and its inhibiting cancer cell motility.
    The Journal of biological chemistry, 2012, Apr-20, Volume: 287, Issue:17

    Topics: Cell Line, Tumor; Cell Movement; Gene Expression Regulation, Neoplastic; Guanine Nucleotide Dissociation Inhibitors; Humans; Lysine; Models, Biological; Neoplasm Invasiveness; Neoplasm Metastasis; Neoplasms; rho GTP-Binding Proteins; rho Guanine Nucleotide Dissociation Inhibitor alpha; rho-Specific Guanine Nucleotide Dissociation Inhibitors; Sumoylation; Wound Healing; X-Linked Inhibitor of Apoptosis Protein

2012
Plasticity of melanoma cells induced by neural cell crest conditions and three-dimensional growth.
    Melanoma research, 2012, Volume: 22, Issue:3

    Topics: Acetylation; Cell Adhesion; Cell Culture Techniques; Cell Differentiation; Cell Line, Tumor; Cell Proliferation; Chromatin Assembly and Disassembly; Culture Media, Serum-Free; Dealkylation; Epigenesis, Genetic; Gene Expression Regulation, Neoplastic; Green Fluorescent Proteins; Histone Deacetylase Inhibitors; Histones; Humans; Lysine; Melanoma; Neoplasm Invasiveness; Neural Crest; Phenotype; Signal Transduction; Spheroids, Cellular; Time Factors; Transcription, Genetic; Transfection; Tumor Microenvironment

2012
Lysine 394 is a novel Rad6B-induced ubiquitination site on beta-catenin.
    Biochimica et biophysica acta, 2012, Volume: 1823, Issue:10

    Topics: Armadillo Domain Proteins; beta Catenin; Breast Neoplasms; Catalytic Domain; Cell Line, Tumor; Female; Gene Silencing; Humans; Lysine; Mutation; Neoplasm Invasiveness; Protein Binding; Transcription, Genetic; Ubiquitin; Ubiquitin-Conjugating Enzymes; Ubiquitination; Up-Regulation

2012
PEGylation extends circulation half-life while preserving in vitro and in vivo activity of tissue inhibitor of metalloproteinases-1 (TIMP-1).
    PloS one, 2012, Volume: 7, Issue:11

    Topics: Animals; Cell Line, Tumor; Gelatinases; Half-Life; Humans; Lysine; Matrix Metalloproteinase 3; Matrix Metalloproteinase 9; Matrix Metalloproteinase Inhibitors; Mice; Neoplasm Invasiveness; Polyethylene Glycols; Protease Inhibitors; Recombinant Proteins; Tissue Inhibitor of Metalloproteinase-1

2012
Post-translational modifications of recombinant human lysyl oxidase-like 2 (rhLOXL2) secreted from Drosophila S2 cells.
    The Journal of biological chemistry, 2013, Feb-22, Volume: 288, Issue:8

    Topics: Amino Acid Oxidoreductases; Animals; Breast Neoplasms; Carbohydrates; Catalytic Domain; Cell Line; Drosophila melanogaster; Glycosylation; Humans; Lysine; Mass Spectrometry; Mutagenesis, Site-Directed; Neoplasm Invasiveness; Neoplasm Metastasis; Peptides; Polysaccharides; Protein Folding; Protein Processing, Post-Translational; Quinones; Recombinant Proteins; Solvents

2013
Conformational studies of antimetastatic laminin-1 derived peptides in different solvent systems, using solution NMR spectroscopy.
    The journal of peptide research : official journal of the American Peptide Society, 2003, Volume: 61, Issue:1

    Topics: Amino Acid Sequence; Amino Acid Substitution; Arginine; Basement Membrane; Laminin; Lysine; Models, Molecular; Neoplasm Invasiveness; Nuclear Magnetic Resonance, Biomolecular; Oligopeptides; Protein Binding; Protein Conformation; Protein Structure, Tertiary; Solutions

2003
Antitumor effect of a combination of lysine, proline, arginine, ascorbic acid, and green tea extract on pancreatic cancer cell line MIA PaCa-2.
    International journal of gastrointestinal cancer, 2005, Volume: 35, Issue:2

    Topics: Antioxidants; Arginine; Ascorbic Acid; Cell Proliferation; Cell Survival; Humans; Lysine; Matrix Metalloproteinases; Neoplasm Invasiveness; Pancreatic Neoplasms; Proline; Tea; Tumor Cells, Cultured

2005
Inhibitory effect of a mixture containing ascorbic acid, lysine, proline and green tea extract on critical parameters in angiogenesis.
    Oncology reports, 2005, Volume: 14, Issue:4

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Ascorbic Acid; Cell Line, Tumor; Cell Proliferation; Chick Embryo; Chorioallantoic Membrane; Collagen; Dose-Response Relationship, Drug; Drug Combinations; Extracellular Matrix; Fibroblast Growth Factor 2; Formaldehyde; Humans; Immunohistochemistry; In Vitro Techniques; Laminin; Lysine; Matrix Metalloproteinases; Mice; Mice, Inbred C57BL; Mice, Nude; Neoplasm Invasiveness; Neoplasm Metastasis; Neoplasm Transplantation; Neovascularization, Pathologic; Osteosarcoma; Plant Extracts; Platelet-Derived Growth Factor; Proline; Proteoglycans; Tea; Tetrazolium Salts; Thiazoles; Time Factors; Transforming Growth Factor beta; Transforming Growth Factor beta1; Vascular Endothelial Growth Factor A

2005
Inhibition of matrix metalloproteinase-2 secretion and invasion by human ovarian cancer cell line SK-OV-3 with lysine, proline, arginine, ascorbic acid and green tea extract.
    The journal of obstetrics and gynaecology research, 2006, Volume: 32, Issue:2

    Topics: Amino Acids; Arginine; Ascorbic Acid; Cell Division; Cell Line, Tumor; Enzyme Inhibitors; Female; Humans; Lysine; Matrix Metalloproteinase 2; Matrix Metalloproteinase Inhibitors; Neoplasm Invasiveness; Ovarian Neoplasms; Proline; Tea

2006
Plasminogen binding and activation at the breast cancer cell surface: the integral role of urokinase activity.
    Breast cancer research : BCR, 2007, Volume: 9, Issue:1

    Topics: Breast Neoplasms; Female; Fibrinolysin; Humans; Lysine; Neoplasm Invasiveness; Plasminogen; Receptors, Cell Surface; Receptors, Urokinase Plasminogen Activator; Up-Regulation; Urokinase-Type Plasminogen Activator

2007
Anti-tumor effect of ascorbic acid, lysine, proline, arginine, and epigallocatechin gallate on prostate cancer cell lines PC-3, LNCaP, and DU145.
    Research communications in molecular pathology and pharmacology, 2004, Volume: 115-116

    Topics: Antioxidants; Arginine; Ascorbic Acid; Catechin; Cell Line, Tumor; Cell Proliferation; Chemistry, Pharmaceutical; Collagen; Dose-Response Relationship, Drug; Drug Combinations; Drug Synergism; Formazans; Humans; Laminin; Lysine; Male; Matrix Metalloproteinases; Neoplasm Invasiveness; Proline; Prostatic Neoplasms; Proteoglycans; Tetrazolium Salts

2004
Inhibitory effects of a nutrient mixture on human testicular cancer cell line NT 2/DT matrigel invasion and MMP activity.
    Medical oncology (Northwood, London, England), 2007, Volume: 24, Issue:2

    Topics: Amino Acids; Antineoplastic Agents; Antioxidants; Arginine; Ascorbic Acid; Camellia sinensis; Cell Line, Tumor; Cell Proliferation; Collagen; Drug Combinations; Humans; Laminin; Lysine; Male; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Matrix Metalloproteinase Inhibitors; Neoplasm Invasiveness; Plant Extracts; Proline; Proteoglycans; Testicular Neoplasms

2007
Inhibition of glioma cell line A-172 MMP activity and cell invasion in vitro by a nutrient mixture.
    Medical oncology (Northwood, London, England), 2007, Volume: 24, Issue:2

    Topics: Acetylcysteine; Amino Acids; Antineoplastic Agents; Arginine; Ascorbic Acid; Camellia sinensis; Cell Line, Tumor; Cell Proliferation; Cell Survival; Collagen; Drug Combinations; Glioma; Humans; Laminin; Lysine; Matrix Metalloproteinase Inhibitors; Matrix Metalloproteinases; Neoplasm Invasiveness; Plant Extracts; Proline; Proteoglycans

2007
Inhibition of cell invasion and MMP production by a nutrient mixture in malignant liposarcoma cell line SW-872.
    Medical oncology (Northwood, London, England), 2007, Volume: 24, Issue:4

    Topics: Antineoplastic Agents; Apoptosis; Ascorbic Acid; Camellia sinensis; Cell Line, Tumor; Cell Proliferation; Drug Combinations; Gelatinases; Humans; Liposarcoma; Lysine; Matrix Metalloproteinase Inhibitors; Neoplasm Invasiveness; Plant Extracts

2007
Maillard products as biomarkers in cancer.
    Annals of the New York Academy of Sciences, 2008, Volume: 1126

    Topics: Biomarkers, Tumor; Breast Neoplasms; Cytoplasm; Female; Glycolysis; Humans; Immunohistochemistry; Lysine; Maillard Reaction; Neoplasm Invasiveness

2008