Compounds > lysine
Page last updated: 2024-08-17

lysine and Insulin Sensitivity

lysine has been researched along with Insulin Sensitivity in 53 studies

Research

Studies (53)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (1.89)18.2507
2000's15 (28.30)29.6817
2010's27 (50.94)24.3611
2020's10 (18.87)2.80

Authors

AuthorsStudies
Li, R; Qiao, J; Wang, S; Ye, Z; Zhang, C; Zhang, Y; Zhao, Y1
Berendschot, TT; de Goei, EE; Eussen, SJ; Hanssen, H; Houben, AJ; Linkens, AM; Mari, A; Niessen, PM; Schalkwijk, CG; Scheijen, JL; Stehouwer, CD; Streese, L; Van den Eynde, MD; van den Waarenburg, MP; van Dongen, MC; van Gool, CC; Wijckmans, NE1
Brunetta, HS; Handy, RM; Holloway, GP; Mericskay, M; Momken, I; Nunes, EA; Petrick, HL; Pignanelli, C; Piquereau, J1
Gordts, PLSM; Harrington, AR; Nora, C; Omar, I; Pollow, DP; Ramms, B; Sander, M; Wortham, M; Zhu, H1
Cao, B; Fan, L; Hu, X; Wang, M; Yu, W; Zhang, B1
Hisamatsu, T; Ida, Y; Kato, Y; Miyoshi, S; Nakamura, H; Ohnishi, H; Okamoto, S; Tokunaga, K; Toue, S; Yoneyama, R1
Cañellas, N; Correig, X; Escobar-Morreale, HF; Insenser, M; Luque-Ramírez, M; Martínez-García, MÁ1
Crown, SB; Davidson, MT; Draper, JA; Fisher-Wellman, KH; Grimsrud, PA; Koves, TR; Lantier, L; Muoio, DM; Narowski, TM; Slentz, DH; Torres, MJ; Wasserman, DH; Williams, AS1
Choi, YG; Nguyen, HP; Sul, HS; Viscarra, JA; Wang, Y1
Hu, L; Ma, Q; Meng, Q; Shan, A; Shao, C; Sun, Y; Zhou, X; Zhu, J1
Clifton, PM; Keogh, JB; Kim, Y1
Anderson, KA; Backos, DS; Campbell, JE; Capra, JA; Douros, JD; Fisher-Wellman, K; Green, MF; Grimsrud, PA; Hirschey, MD; Huynh, FK; Ilkayeva, OR; Madsen, AS; Muoio, DM; Olsen, CA; Peterson, BS; Sivley, RM; Stevens, RD; Stuart, JD; Thompson, JW; Wagner, GR1
Hirschey, MD; Hu, X; Huynh, FK; Johnson, JD; Lin, Z1
Gaikwad, AB; Goru, SK; Kadakol, A; Malek, V1
Dain, JA; Kindler, JM; Laing, EM; Lewis, RD; Liu, W1
Cai, X; Cao, B; Gao, F; Hu, D; Ji, L; Li, J; Li, Y; Wang, H; Xiao, R; Xiong, L; Xu, J; Zhang, X1
Bierhaus, A; Blaak, EE; Buurman, WA; Gaens, KH; Goossens, GH; Greve, JW; Niessen, HW; Niessen, PM; Rensen, SS; Schalkwijk, CG; Stehouwer, CD; van der Kallen, CJ; van Greevenbroek, MM; van Zandvoort, MA1
Bordner, AJ; Cordova, JM; Langlais, PR; Lefort, N; Mandarino, LJ; McLean, CG; Mielke, C; Ozkan, SB; Te, JA; Willis, WT1
Kim, SH; Lee, JH; Park, JY; Park, S1
Borghi, R; Cammarata, S; Monacelli, F; Nencioni, A; Odetti, P; Piccini, A; Tabaton, M1
Goda, T; Mochizuki, K; Morioka, K; Muramatsu, T; Suzuki, T1
Daniel, H; Ecker, J; Giesbertz, P; Höfle, AS; Padberg, I; Rein, D; Spanier, B1
Chand, V; Cooper, ME; de Courten, B; de Courten, MP; Dougherty, SL; Forbes, JM; Kingwell, BA; Schalkwijk, CG; Scheijen, JL; Schlaich, M; Soldatos, G; Sourris, KC; Straznicky, N; Walker, KZ1
Beelman, RB; Cai, W; Calvo, MS; Goh, BC; Kalaras, MD; Mehrotra, A; Nadkarni, G; Uribarri, J; Wang, L1
Albrecht, E; Chen, J; Gao, S; Huang, Y; Yang, X; Zhao, R1
Aller, R; Conde, R; de Luis, DA; Gonzalez Sagrado, M; Izaola, O1
Bai, J; Jiang, X; Shen, D; Wan, J; Wang, T1
Goda, T; Mochizuki, K; Sakurai, N1
Fan, W; Li, P; Lu, M; Olefsky, JM; Pferdekamper, J; Saberi, M; Schenk, S1
Cheng, XW; Ikeda, N; Imamura, A; Murakami, R; Murohara, T; Numaguchi, Y; Okumura, K; Suzuki, M; Takahashi, R; Yoshikane, M1
Ataei, F; Bakhtiyari, S; Gerayesh-Nejad, S; Gulkho, S; Hanachi, P; Larijani, B; Meshkani, R; Mohammadi, M; Mohammadtaghvaei, N; Parvaneh, L; Saberi, H; Zargari, M1
Basta, G; Del Turco, S; Gastaldelli, A; Navarra, T1
Gajdoš, M; Klenovicsová, K; Krivošíková, Z; Sebeková, K1
Blättler, SM; Chim, H; Cunningham, JT; Gygi, SP; Haas, W; Liu, H; Puigserver, P; Romanino, K; Rüegg, MA; Shi, Y; Verdeguer, F1
Kuriyan, R; Kurpad, AV; Raj, T; Regan, MM; Sambashivaiah, S; Unni, US; Uthappa, S; Vaz, M1
Accili, D; Farmer, SR; Gu, W; Kon, N; Lee, S; Qiang, L; Rosenbaum, M; Wang, L; Zhang, Y; Zhao, W; Zhao, Y1
Caricilli, AM; Carvalheira, JB; Carvalho, BM; Carvalho-Filho, MA; Cintra, DE; Curi, R; da Silva, AS; De Souza, CT; Guadagnini, D; Hirabara, S; Katashima, CK; Pauli, JR; Ropelle, ER; Saad, MJ; Velloso, LA1
Li, Y; Niu, Y; Sun, C; Wang, C; Wang, F; Wang, M; Zhao, Y1
Boor, P; Celec, P; Fogliano, V; Klenovics, KS; Sebeková, K; Somoza, V1
Kellow, NJ; Savige, GS1
Abate, N; Cabo-Chan, A; Carulli, L; Chandalia, M; Grundy, SM; Snell, PG1
Cooper, GJ; Gerwig, GJ; Lam, KS; Lu, G; Vliegenthart, JF; Wang, Y; Wong, WP; Xu, A1
Fujimoto, M; Kaneki, M; Kunii, K; Martyn, JA; Shimizu, N; Ueki, K1
Fu, Y; Katsuya, T; Masuo, K; Ogihara, T; Rakugi, H; Tuck, ML1
Asghar, M; Lokhandwala, MF1
Albrechtsen, A; Borch-Johnsen, K; Ek, J; Glümer, C; Grarup, N; Hansen, T; Jørgensen, T; Pedersen, O; Urhammer, SA1
Cai, W; Ferrucci, L; Goodman, S; Peppa, M; Striker, G; Uribarri, J; Vlassara, H1
Basta, G; Basu, S; de Caterina, R; de Faire, U; Fisher, RM; Hamsten, A; Hellenius, ML; Rosell, M; Silveira, A; Sjögren, P; Vessby, B1
Igarashi, Y; Inokuchi, J; Kabayama, K; Kinjo, M; Loberto, N; Prinetti, A; Saito, K; Sato, T; Sonnino, S1
Baatz, JE; Baynes, JW; Bethard, J; Blatnik, M; Brock, JW; Frizzell, N; Nagai, R; Thorpe, SR; Walla, MD1
Carvalheira, JB; Carvalho-Filho, MA; Cintra, DE; De Souza, CT; Moraes, JC; Pauli, JR; Ropelle, ER; Saad, MJ; Velloso, LA1
Diamanti-Kandarakis, E; Kandaraki, E; Katsikis, I; Panidis, D; Papavassiliou, AG; Piouka, A; Piperi, C1
Bouchard, C; Després, JP; Dionne, FT; Lupien, PJ; Moorjani, S; Nadeau, A; Prud'homme, D; Tchernof, A; Vohl, MC1

Reviews

1 review(s) available for lysine and Insulin Sensitivity

ArticleYear
Dietary advanced glycation end-product restriction for the attenuation of insulin resistance, oxidative stress and endothelial dysfunction: a systematic review.
    European journal of clinical nutrition, 2013, Volume: 67, Issue:3

    Topics: Diabetes Mellitus; Diet; Endothelium; Glycation End Products, Advanced; Humans; Insulin Resistance; Lysine; Oxidative Stress; Randomized Controlled Trials as Topic; Renal Insufficiency

2013

Trials

5 trial(s) available for lysine and Insulin Sensitivity

ArticleYear
A 4-week high-AGE diet does not impair glucose metabolism and vascular function in obese individuals.
    JCI insight, 2022, 03-22, Volume: 7, Issue:6

    Topics: Diabetes Mellitus, Type 2; Diet; Glucose; Glycation End Products, Advanced; Humans; Inflammation; Insulin Resistance; Lipids; Lysine; Male; Obesity

2022
Effects of Two Different Dietary Patterns on Inflammatory Markers, Advanced Glycation End Products and Lipids in Subjects without Type 2 Diabetes: A Randomised Crossover Study.
    Nutrients, 2017, Mar-29, Volume: 9, Issue:4

    Topics: Adult; Biomarkers; Cholesterol; Cross-Over Studies; Diabetes Mellitus, Type 2; Diet, Healthy; Diet, Western; Feeding Behavior; Female; Food Handling; Glycation End Products, Advanced; Humans; Inflammation; Insulin Resistance; Lipids; Lysine; Male; Middle Aged; Plasminogen Inactivators; Reference Values; Triglycerides; Young Adult

2017
Pentosidine Is Associated With Cortical Bone Geometry and Insulin Resistance in Otherwise Healthy Children.
    Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research, 2019, Volume: 34, Issue:8

    Topics: Adolescent; Arginine; Child; Cortical Bone; Female; Humans; Insulin Resistance; Lysine; Male; Radius; Tibia

2019
Diet low in advanced glycation end products increases insulin sensitivity in healthy overweight individuals: a double-blind, randomized, crossover trial.
    The American journal of clinical nutrition, 2016, Volume: 103, Issue:6

    Topics: Adult; Blood Glucose; Cross-Over Studies; Diet; Double-Blind Method; Female; Glucose Clamp Technique; Glucose Tolerance Test; Glycation End Products, Advanced; Humans; Imidazolidines; Insulin; Insulin Resistance; Lysine; Male; Middle Aged; Overweight; Pyruvaldehyde

2016
The effect of a controlled 8-week metabolic ward based lysine supplementation on muscle function, insulin sensitivity and leucine kinetics in young men.
    Clinical nutrition (Edinburgh, Scotland), 2012, Volume: 31, Issue:6

    Topics: Adolescent; Adult; Anthropometry; Body Composition; Diet; Dietary Supplements; Humans; Insulin Resistance; Leucine; Lysine; Male; Muscle Strength; Muscle, Skeletal; Nutritional Requirements; Young Adult

2012

Other Studies

47 other study(ies) available for lysine and Insulin Sensitivity

ArticleYear
Amino acid signatures in relation to polycystic ovary syndrome and increased risk of different metabolic disturbances.
    Reproductive biomedicine online, 2022, Volume: 44, Issue:4

    Topics: Alanine; Amino Acids; Body Mass Index; Female; Glycine; Humans; Insulin Resistance; Lysine; Metabolic Syndrome; Obesity; Polycystic Ovary Syndrome; Tyrosine

2022
Nitrate consumption preserves HFD-induced skeletal muscle mitochondrial ADP sensitivity and lysine acetylation: A potential role for SIRT1.
    Redox biology, 2022, Volume: 52

    Topics: Acetylation; Adenosine Diphosphate; AMP-Activated Protein Kinases; Animals; Diet, High-Fat; Glucose; Insulin; Insulin Resistance; Lysine; Mice; Mice, Inbred C57BL; Muscle, Skeletal; Nitrates; Proto-Oncogene Proteins c-akt; Sirtuin 1

2022
Systemic LSD1 Inhibition Prevents Aberrant Remodeling of Metabolism in Obesity.
    Diabetes, 2022, 12-01, Volume: 71, Issue:12

    Topics: Animals; Diabetes Mellitus, Type 2; Histone Demethylases; Inflammation; Insulin; Insulin Resistance; Lipid Metabolism; Lipids; Liver; Lysine; Mice; Mice, Inbred C57BL; Non-alcoholic Fatty Liver Disease; Obesity

2022
Distinctive effects of different types of advanced glycation end-products (AGEs) on liver glucose metabolism.
    Food & function, 2022, Oct-31, Volume: 13, Issue:21

    Topics: Animals; Glucose; Glycation End Products, Advanced; Insulin Resistance; Liver; Lysine; Magnesium Oxide; Mice; Pyruvaldehyde

2022
Plasma free amino acid profiles are associated with serum high molecular weight adiponectin levels in Japanese medical check-up population without type 2 diabetes mellitus.
    Amino acids, 2023, Volume: 55, Issue:5

    Topics: Adiponectin; Amino Acids; Cross-Sectional Studies; Diabetes Mellitus, Type 2; East Asian People; Glutamates; Humans; Insulin Resistance; Lysine; Molecular Weight; Tryptophan

2023
Serum metabolomics profiling by proton nuclear magnetic resonance spectrometry of the response to single oral macronutrient challenges in women with polycystic ovary syndrome (PCOS) compared with male and female controls.
    Biology of sex differences, 2023, 09-22, Volume: 14, Issue:1

    Topics: 3-Hydroxybutyric Acid; Amino Acids; Female; Glucose; Humans; Insulin Resistance; Lysine; Magnetic Resonance Spectroscopy; Male; Metabolomics; Nutrients; Obesity; Polycystic Ovary Syndrome; Protons; Young Adult

2023
Disruption of Acetyl-Lysine Turnover in Muscle Mitochondria Promotes Insulin Resistance and Redox Stress without Overt Respiratory Dysfunction.
    Cell metabolism, 2020, 01-07, Volume: 31, Issue:1

    Topics: Acetyl Coenzyme A; Acetylation; Animals; Carnitine O-Acetyltransferase; Creatine Kinase; Diet, High-Fat; Energy Metabolism; Homeostasis; Hydrogen Peroxide; Insulin; Insulin Resistance; Lysine; Male; Membrane Potential, Mitochondrial; Mice; Mice, Knockout; Mitochondria, Muscle; Mitochondrial Proteins; Oxidation-Reduction; Oxidative Stress; Proteome; Sirtuin 3; Thermodynamics

2020
Histone demethylase JMJD1C is phosphorylated by mTOR to activate de novo lipogenesis.
    Nature communications, 2020, 02-07, Volume: 11, Issue:1

    Topics: Animals; Diet, High-Fat; Eating; Female; Gene Expression Regulation; Genome-Wide Association Study; Hep G2 Cells; Histones; Humans; Insulin; Insulin Resistance; Jumonji Domain-Containing Histone Demethylases; Lipogenesis; Lysine; Male; Mice, Inbred C57BL; Mice, Knockout; Oxidoreductases, N-Demethylating; Phosphorylation; Promoter Regions, Genetic; TOR Serine-Threonine Kinases; Triglycerides; Upstream Stimulatory Factors

2020
Threonine, but Not Lysine and Methionine, Reduces Fat Accumulation by Regulating Lipid Metabolism in Obese Mice.
    Journal of agricultural and food chemistry, 2020, Apr-29, Volume: 68, Issue:17

    Topics: Adipose Tissue, Brown; Animals; Anti-Obesity Agents; Diet, High-Fat; Humans; Insulin Resistance; Lipid Metabolism; Lipogenesis; Lysine; Male; Methionine; Mice; Mice, Inbred C57BL; Mice, Obese; Obesity; Threonine; Uncoupling Protein 1

2020
SIRT4 Is a Lysine Deacylase that Controls Leucine Metabolism and Insulin Secretion.
    Cell metabolism, 2017, Apr-04, Volume: 25, Issue:4

    Topics: Amidohydrolases; Amino Acid Sequence; Animals; Carbon-Carbon Ligases; Glucose; HEK293 Cells; Homeostasis; Humans; Insulin; Insulin Resistance; Insulin Secretion; Leucine; Lysine; Metabolic Flux Analysis; Mice, Inbred C57BL; Mice, Knockout; Mitochondrial Proteins; Models, Molecular; Phylogeny; Sirtuins

2017
Loss of sirtuin 4 leads to elevated glucose- and leucine-stimulated insulin levels and accelerated age-induced insulin resistance in multiple murine genetic backgrounds.
    Journal of inherited metabolic disease, 2018, Volume: 41, Issue:1

    Topics: Age Factors; Animals; Biomarkers; Blood Glucose; Female; Genetic Predisposition to Disease; In Vitro Techniques; Insulin; Insulin Resistance; Leucine; Lipid Metabolism; Lysine; Male; Metabolism, Inborn Errors; Mice, 129 Strain; Mice, Inbred C57BL; Mice, Knockout; Mitochondrial Proteins; Phenotype; Protein Processing, Post-Translational; Sirtuins; Up-Regulation

2018
Esculetin ameliorates vascular perturbation by intervening in the occupancy of H2BK120Ub at At1, At2, Tgfβ1 and Mcp1 promoter gene in thoracic aorta of IR and T2D rats.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2017, Volume: 95

    Topics: Acetylcholine; Angiotensin II; Animals; Aorta; Blood Vessels; Chemokine CCL2; Diabetes Mellitus, Type 2; Gene Expression Regulation; Hemodynamics; Histones; Insulin Resistance; Lysine; Muscle Relaxation; Myocardial Contraction; Promoter Regions, Genetic; Rats; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; RNA, Messenger; Transforming Growth Factor beta1; Ubiquitin; Umbelliferones

2017
Acute insulin resistance mediated by advanced glycation endproducts in severely burned rats.
    Critical care medicine, 2014, Volume: 42, Issue:6

    Topics: Animals; Blood Glucose; Burns; Cell Line; Glucose Tolerance Test; Glycation End Products, Advanced; Glycogen Synthase Kinase 3; Hyperglycemia; Insulin; Insulin Resistance; Kaplan-Meier Estimate; Lysine; Phosphorylation; Positron-Emission Tomography; Prospective Studies; Proto-Oncogene Proteins c-akt; Rats; Rats, Sprague-Dawley

2014
Nε-(carboxymethyl)lysine-receptor for advanced glycation end product axis is a key modulator of obesity-induced dysregulation of adipokine expression and insulin resistance.
    Arteriosclerosis, thrombosis, and vascular biology, 2014, Volume: 34, Issue:6

    Topics: Adipokines; Adipose Tissue; Adult; Animals; Cells, Cultured; Female; Humans; Insulin Resistance; Lipid Metabolism; Lysine; Male; Mice; Mice, Inbred C57BL; Middle Aged; Obesity; Receptor for Advanced Glycation End Products; Receptors, Immunologic

2014
Adenine nucleotide translocase is acetylated in vivo in human muscle: Modeling predicts a decreased ADP affinity and altered control of oxidative phosphorylation.
    Biochemistry, 2014, Jun-17, Volume: 53, Issue:23

    Topics: Acetylation; Adenine Nucleotide Translocator 1; Adenosine Diphosphate; Adult; Binding Sites; Body Mass Index; Down-Regulation; Female; Humans; Insulin Resistance; Lysine; Male; Middle Aged; Mitochondria, Muscle; Molecular Docking Simulation; Molecular Dynamics Simulation; Motor Activity; Muscle Proteins; Muscle, Skeletal; Obesity; Oxidative Phosphorylation; Protein Processing, Post-Translational

2014
Plasma levels of lysine, tyrosine, and valine during pregnancy are independent risk factors of insulin resistance and gestational diabetes.
    Metabolic syndrome and related disorders, 2015, Volume: 13, Issue:2

    Topics: Adult; Aging; Asian People; Blood Glucose; Blood Pressure; Diabetes, Gestational; Diet; Energy Intake; Female; Glucose Tolerance Test; Humans; Insulin; Insulin Resistance; Lysine; Pregnancy; Risk Factors; Tyrosine; Valine

2015
Amnestic mild cognitive impairment and conversion to Alzheimer's disease: insulin resistance and glycoxidation as early biomarker clusters.
    Journal of Alzheimer's disease : JAD, 2015, Volume: 45, Issue:1

    Topics: Aged; Alzheimer Disease; Arginine; Blood Glucose; Case-Control Studies; Cognitive Dysfunction; Disease Progression; Female; Humans; Insulin; Insulin Resistance; Lysine; Male; Malondialdehyde; Neuropsychological Tests; Psychiatric Status Rating Scales; Statistics as Topic

2015
ChREBP binding and histone modifications modulate hepatic expression of the Fasn gene in a metabolic syndrome rat model.
    Nutrition (Burbank, Los Angeles County, Calif.), 2015, Volume: 31, Issue:6

    Topics: Acetylation; Animals; Basic Helix-Loop-Helix Leucine Zipper Transcription Factors; Epigenesis, Genetic; Fatty Acid Synthases; Histone Code; Histones; Insulin; Insulin Resistance; Lipogenesis; Liver; Lysine; Male; Metabolic Syndrome; Methylation; Promoter Regions, Genetic; Protein Processing, Post-Translational; Rats; Rats, Inbred SHR; RNA, Messenger

2015
Metabolite profiling in plasma and tissues of ob/ob and db/db mice identifies novel markers of obesity and type 2 diabetes.
    Diabetologia, 2015, Volume: 58, Issue:9

    Topics: 3-Hydroxybutyric Acid; Adipose Tissue; Animals; Diabetes Mellitus, Type 2; Fatty Acids; Gas Chromatography-Mass Spectrometry; Gene Expression Regulation; Glyoxylates; Insulin Resistance; Leptin; Liver; Lysine; Male; Metabolome; Metabolomics; Mice; Mice, Inbred C57BL; Mice, Obese; Muscle, Skeletal; Obesity; Phosphotyrosine; Signal Transduction; Sorbitol

2015
A Retrospective Study in Adults with Metabolic Syndrome: Diabetic Risk Factor Response to Daily Consumption of Agaricus bisporus (White Button Mushrooms).
    Plant foods for human nutrition (Dordrecht, Netherlands), 2016, Volume: 71, Issue:3

    Topics: Adiponectin; Adult; Agaricus; Antioxidants; beta-Glucans; Biomarkers; Body Mass Index; Chitin; Cholesterol, HDL; Cholesterol, LDL; Diabetes Mellitus, Type 2; Diet; Dinoprost; Ergothioneine; Female; Follow-Up Studies; Glycated Hemoglobin; Humans; Insulin Resistance; Leptin; Linear Models; Lysine; Male; Metabolic Syndrome; Middle Aged; Multivariate Analysis; Oxidative Stress; Polyphenols; Pyruvaldehyde; Retrospective Studies; Risk Factors; Triglycerides; Vitamin D

2016
Maternal butyrate supplementation induces insulin resistance associated with enhanced intramuscular fat deposition in the offspring.
    Oncotarget, 2017, Feb-21, Volume: 8, Issue:8

    Topics: Acetylation; Adipose Tissue; Animal Nutritional Physiological Phenomena; Animals; Blotting, Western; Butyrates; Dietary Supplements; Female; Gene Expression; Histones; Insulin; Insulin Resistance; Lactation; Lipogenesis; Lysine; Male; Muscle, Skeletal; Pregnancy; Prenatal Exposure Delayed Effects; Rats, Sprague-Dawley; Reverse Transcriptase Polymerase Chain Reaction; Triglycerides; Weaning

2017
Influence of Lys656Asn polymorphism of leptin receptor gene on insulin resistance in patients with diabetes mellitus type 2.
    Diabetes research and clinical practice, 2008, Volume: 81, Issue:3

    Topics: Amino Acid Substitution; Asparagine; Body Mass Index; Cytokines; Diabetes Mellitus, Type 2; Humans; Insulin Resistance; Lysine; Obesity; Polymorphism, Genetic; Receptors, Leptin

2008
The effects of E23K polymorphism in Kir6.2 subunit on insulin sensitivity in skeletal muscle cells by long-chain fatty acyl CoA.
    Biochemical and biophysical research communications, 2009, Apr-17, Volume: 381, Issue:4

    Topics: Acyl Coenzyme A; Animals; Cell Line; Glutamic Acid; Humans; Insulin; Insulin Resistance; Lysine; Muscle, Skeletal; Polymorphism, Genetic; Potassium Channels, Inwardly Rectifying; Rats

2009
Modifications of histone H3 at lysine 9 on the adiponectin gene in 3T3-L1 adipocytes.
    Journal of nutritional science and vitaminology, 2009, Volume: 55, Issue:2

    Topics: 3T3-L1 Cells; Acetylation; Adipocytes; Adiponectin; Animals; Gene Expression; Gene Expression Regulation; Histones; Insulin Resistance; Lysine; Methylation; Mice; Protein Processing, Post-Translational; Transcriptional Activation; Tumor Necrosis Factor-alpha

2009
Inducible nitric oxide synthase deficiency in myeloid cells does not prevent diet-induced insulin resistance.
    Molecular endocrinology (Baltimore, Md.), 2010, Volume: 24, Issue:7

    Topics: Animals; Blotting, Western; Bone Marrow Transplantation; Cells, Cultured; Dietary Fats; Enzyme Inhibitors; Immunohistochemistry; Insulin Resistance; Lysine; Macrophages; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Myeloid Cells; Nitric Oxide Synthase Type II; Obesity

2010
High serum concentrations of pentosidine, an advanced glycation end product, are associated with low normal value of ankle-brachial index in apparently healthy men.
    Metabolism: clinical and experimental, 2011, Volume: 60, Issue:5

    Topics: Adult; Aged; Aged, 80 and over; Ankle Brachial Index; Apolipoproteins B; Arginine; Asian People; Body Mass Index; Cholesterol, LDL; Fasting; Glycation End Products, Advanced; Homeostasis; Humans; Insulin; Insulin Resistance; Japan; Lysine; Male; Malondialdehyde; Middle Aged; Protein Processing, Post-Translational

2011
The ENPP1 K121Q polymorphism is not associated with type 2 diabetes and related metabolic traits in an Iranian population.
    Molecular and cellular biochemistry, 2011, Volume: 350, Issue:1-2

    Topics: Adult; Aged; Amino Acid Substitution; Diabetes Mellitus, Type 2; Female; Gene Frequency; Genetic Predisposition to Disease; Genetics, Population; Genotype; Glutamic Acid; Humans; Insulin Resistance; Iran; Lysine; Male; Metabolic Diseases; Middle Aged; Phosphoric Diester Hydrolases; Polymorphism, Single Nucleotide; Pyrophosphatases; Young Adult

2011
Protective role of adiponectin on endothelial dysfunction induced by AGEs: a clinical and experimental approach.
    Microvascular research, 2011, Volume: 82, Issue:1

    Topics: Adiponectin; Adult; Cells, Cultured; Diabetes Mellitus, Type 2; E-Selectin; Endothelial Cells; Endothelium, Vascular; Female; Glucose Tolerance Test; Glycation End Products, Advanced; Humans; Insulin Resistance; Lysine; Male; Middle Aged; Vascular Cell Adhesion Molecule-1

2011
Association of sVAP-1, sRAGE, and CML with lactation-induced insulin sensitivity in young non-diabetic healthy women.
    Clinica chimica acta; international journal of clinical chemistry, 2011, Sep-18, Volume: 412, Issue:19-20

    Topics: Adult; Amine Oxidase (Copper-Containing); Cell Adhesion Molecules; Cohort Studies; Female; Humans; Insulin Resistance; Lactation; Lysine; Receptor for Advanced Glycation End Products; Receptors, Immunologic; Reference Values

2011
Yin Yang 1 deficiency in skeletal muscle protects against rapamycin-induced diabetic-like symptoms through activation of insulin/IGF signaling.
    Cell metabolism, 2012, Apr-04, Volume: 15, Issue:4

    Topics: Animals; Diabetes Mellitus, Experimental; Enhancer of Zeste Homolog 2 Protein; Gene Expression Regulation; Histone-Lysine N-Methyltransferase; Histones; Humans; Insulin; Insulin Resistance; Insulin-Like Growth Factor I; Lipid Metabolism; Liver; Lysine; Methylation; Mice; Mice, Knockout; Models, Biological; Muscle, Skeletal; Organ Specificity; Polycomb Repressive Complex 2; Polycomb-Group Proteins; Promoter Regions, Genetic; Protein Binding; Repressor Proteins; Signal Transduction; Sirolimus; YY1 Transcription Factor

2012
Brown remodeling of white adipose tissue by SirT1-dependent deacetylation of Pparγ.
    Cell, 2012, Aug-03, Volume: 150, Issue:3

    Topics: 3T3 Cells; Acetylation; Adipose Tissue, Brown; Adipose Tissue, White; Adult; Amino Acid Sequence; Animals; Cells, Cultured; Energy Metabolism; Female; Humans; Insulin Resistance; Ligands; Lysine; Mice; Mice, 129 Strain; Mice, Inbred C57BL; Models, Molecular; Molecular Sequence Data; Mutagenesis, Site-Directed; Mutation; Obesity; PPAR gamma; Resveratrol; Sequence Alignment; Sirtuin 1; Stilbenes; Thermogenesis; Thiazolidinediones

2012
Targeted disruption of inducible nitric oxide synthase protects against aging, S-nitrosation, and insulin resistance in muscle of male mice.
    Diabetes, 2013, Volume: 62, Issue:2

    Topics: Aging; Animals; Enzyme Inhibitors; Insulin; Insulin Resistance; Lysine; Male; Mice; Mice, Inbred C57BL; Muscle, Skeletal; Nitric Oxide Synthase Type II; Nitrosation; Physical Conditioning, Animal; Signal Transduction

2013
Activated glucose-6-phosphate dehydrogenase is associated with insulin resistance by upregulating pentose and pentosidine in diet-induced obesity of rats.
    Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme, 2012, Volume: 44, Issue:13

    Topics: Animals; Arginine; Diet, High-Fat; Enzyme Activation; Glucosephosphate Dehydrogenase; Insulin Resistance; Lysine; Male; Obesity; Oxidative Stress; Pentoses; Rats; Rats, Wistar; Up-Regulation

2012
Advanced glycation end products in infant formulas do not contribute to insulin resistance associated with their consumption.
    PloS one, 2013, Volume: 8, Issue:1

    Topics: Breast Feeding; Cohort Studies; Cross-Sectional Studies; Diet; Female; Glycation End Products, Advanced; Humans; Infant; Infant Formula; Inflammation; Insulin Resistance; Lysine; Male; Milk, Human; Oxidative Stress

2013
Genetic polymorphism PC-1 K121Q and ethnic susceptibility to insulin resistance.
    The Journal of clinical endocrinology and metabolism, 2003, Volume: 88, Issue:12

    Topics: Adult; Asian People; Female; Gene Frequency; Genetic Predisposition to Disease; Glucose Clamp Technique; Glucose Tolerance Test; Glutamine; Humans; Hyperinsulinism; India; Insulin Resistance; Lysine; Male; Middle Aged; Phosphoric Diester Hydrolases; Polymorphism, Genetic; Pyrophosphatases; White People

2003
Proteomic and functional characterization of endogenous adiponectin purified from fetal bovine serum.
    Proteomics, 2004, Volume: 4, Issue:12

    Topics: Adiponectin; Amino Acid Sequence; Animals; Blotting, Western; Cattle; Chromatography, High Pressure Liquid; Electrophoresis, Gel, Two-Dimensional; Escherichia coli; Fatty Acids, Nonesterified; Glucose; Glucose Tolerance Test; Glycosylation; Insulin; Insulin Resistance; Intercellular Signaling Peptides and Proteins; Isoelectric Focusing; Lipid Metabolism; Liver; Lysine; Magnetic Resonance Spectroscopy; Male; Mass Spectrometry; Mice; Mice, Inbred C57BL; Molecular Sequence Data; Protein Processing, Post-Translational; Protein Structure, Tertiary; Proteomics; Recombinant Proteins; Time Factors; Triglycerides; Trypsin

2004
A role for iNOS in fasting hyperglycemia and impaired insulin signaling in the liver of obese diabetic mice.
    Diabetes, 2005, Volume: 54, Issue:5

    Topics: Animals; Cells, Cultured; Diabetes Mellitus, Type 2; Enzyme Inhibitors; Fasting; Hepatocytes; Hyperglycemia; Insulin; Insulin Resistance; Liver; Lysine; Male; Mice; Mice, Obese; Nitric Oxide Donors; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Phosphatidylinositol 3-Kinases; Signal Transduction

2005
Lys418Asn polymorphism of the alpha2-adrenoceptor gene relates to serum uric acid levels but not to insulin sensitivity.
    Hypertension (Dallas, Tex. : 1979), 2005, Volume: 46, Issue:1

    Topics: Adult; Alleles; Asparagine; Gene Frequency; Genotype; Glycine; Homeostasis; Humans; Hyperuricemia; Insulin Resistance; Lysine; Male; Middle Aged; Norepinephrine; Polymorphism, Genetic; Predictive Value of Tests; Prevalence; Receptors, Adrenergic, alpha-2; Time Factors; Uric Acid; Waist-Hip Ratio

2005
Antioxidant tempol lowers age-related increases in insulin resistance in Fischer 344 rats.
    Clinical and experimental hypertension (New York, N.Y. : 1993), 2006, Volume: 28, Issue:5

    Topics: Age Factors; Aging; Animals; Antioxidants; Biomarkers; Blood Glucose; Blood Proteins; Cyclic N-Oxides; Dietary Supplements; Homeostasis; Insulin; Insulin Resistance; Kidney Tubules, Proximal; Lysine; Male; Malondialdehyde; Models, Animal; Oxidative Stress; Rats; Rats, Inbred F344; Spin Labels; Triglycerides

2006
Studies of the relationship between the ENPP1 K121Q polymorphism and type 2 diabetes, insulin resistance and obesity in 7,333 Danish white subjects.
    Diabetologia, 2006, Volume: 49, Issue:9

    Topics: Adult; Aged; Blood Glucose; Body Mass Index; Case-Control Studies; Cohort Studies; Denmark; Diabetes Mellitus, Type 2; Female; Gene Frequency; Genotype; Glucose Tolerance Test; Glutamine; Humans; Insulin Resistance; Lysine; Male; Middle Aged; Obesity; Odds Ratio; Phosphoric Diester Hydrolases; Polymorphism, Genetic; Pyrophosphatases; Regression Analysis; White People

2006
Circulating glycotoxins and dietary advanced glycation endproducts: two links to inflammatory response, oxidative stress, and aging.
    The journals of gerontology. Series A, Biological sciences and medical sciences, 2007, Volume: 62, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Aging; C-Reactive Protein; Diet; Dinoprost; Energy Intake; Female; Glycation End Products, Advanced; Humans; Inflammation; Insulin Resistance; Lysine; Male; Middle Aged; Oxidative Stress; Pyruvaldehyde

2007
Markers of endothelial activity are related to components of the metabolic syndrome, but not to circulating concentrations of the advanced glycation end-product N epsilon-carboxymethyl-lysine in healthy Swedish men.
    Atherosclerosis, 2007, Volume: 195, Issue:2

    Topics: Alcohol Drinking; Biomarkers; Cohort Studies; E-Selectin; Endothelium, Vascular; Feeding Behavior; Glycation End Products, Advanced; Humans; Inflammation; Insulin; Insulin Resistance; Intercellular Adhesion Molecule-1; Lysine; Male; Metabolic Syndrome; Middle Aged; Oxidative Stress; Risk Factors; Sweden; Vascular Cell Adhesion Molecule-1

2007
Dissociation of the insulin receptor and caveolin-1 complex by ganglioside GM3 in the state of insulin resistance.
    Proceedings of the National Academy of Sciences of the United States of America, 2007, Aug-21, Volume: 104, Issue:34

    Topics: 3T3-L1 Cells; Animals; Caveolin 1; Cell Survival; G(M3) Ganglioside; Insulin Resistance; Lysine; Mice; Protein Binding; Receptor, Insulin; Signal Transduction

2007
Succination of protein thiols during adipocyte maturation: a biomarker of mitochondrial stress.
    The Journal of biological chemistry, 2007, Nov-23, Volume: 282, Issue:47

    Topics: 3T3 Cells; Adipocytes; Adipogenesis; Adipose Tissue; Animals; Biomarkers; Cell Differentiation; Citric Acid Cycle; Cysteine; Diabetes Complications; Diabetes Mellitus, Type 2; Fibroblasts; Fumarates; Humans; Insulin Resistance; Lysine; Mice; Mitochondria; Obesity; Protein Processing, Post-Translational; Risk Factors; Stress, Physiological; Succinic Acid; Sulfhydryl Compounds

2007
Acute physical exercise reverses S-nitrosation of the insulin receptor, insulin receptor substrate 1 and protein kinase B/Akt in diet-induced obese Wistar rats.
    The Journal of physiology, 2008, Jan-15, Volume: 586, Issue:2

    Topics: Adaptor Proteins, Signal Transducing; AMP-Activated Protein Kinase Kinases; Animals; Diet; Disease Models, Animal; Enzyme Inhibitors; Insulin Receptor Substrate Proteins; Insulin Resistance; Lysine; Male; Nitric Oxide Donors; Nitric Oxide Synthase Type II; Obesity; Physical Conditioning, Animal; Protein Kinases; Proto-Oncogene Proteins c-akt; Rats; Rats, Wistar; Receptor, Insulin; S-Nitrosoglutathione; Signal Transduction

2008
Increased serum advanced glycation end-products is a distinct finding in lean women with polycystic ovary syndrome (PCOS).
    Clinical endocrinology, 2008, Volume: 69, Issue:4

    Topics: Adult; Body Mass Index; Case-Control Studies; Female; Glycation End Products, Advanced; Humans; Insulin Resistance; Lysine; Polycystic Ovary Syndrome; Sensitivity and Specificity; Thinness; Up-Regulation; Waist-Hip Ratio; Young Adult

2008
The apoB-100 gene EcoRI polymorphism influences the relationship between features of the insulin resistance syndrome and the hyper-apoB and dense LDL phenotype in men.
    Diabetes, 1996, Volume: 45, Issue:10

    Topics: Adipose Tissue; Adult; Apolipoprotein B-100; Apolipoproteins B; Blood Glucose; Body Mass Index; Cholesterol; Cholesterol, HDL; Cholesterol, LDL; Codon; Deoxyribonuclease EcoRI; Fatty Acids, Nonesterified; Genotype; Glucose Tolerance Test; Glutamic Acid; Heterozygote; Humans; Insulin Resistance; Lipoproteins, LDL; Lysine; Male; Phenotype; Polymorphism, Restriction Fragment Length; Triglycerides

1996