lysine has been researched along with Hypoxia in 67 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 10 (14.93) | 18.7374 |
| 1990's | 8 (11.94) | 18.2507 |
| 2000's | 16 (23.88) | 29.6817 |
| 2010's | 17 (25.37) | 24.3611 |
| 2020's | 16 (23.88) | 2.80 |
| Authors | Studies |
|---|---|
| Jung, M; Staudt, M | 1 |
| Chen, X; Deng, H; Jia, S; Liao, Q; Liu, X; Ouyang, G; Sun, X; Tang, J; Wang, Z; Xiao, W; Zha, H; Zhu, C | 1 |
| Klionsky, DJ; Yu, G | 1 |
| Dong, W; Kang, Q; Liu, G; Luo, H; Peng, W; Tian, X; Wang, L; Wang, T; Xie, Z; Zhang, F; Zhang, J; Zheng, X; Zhu, X | 1 |
| Chen, F; Ko, CN; Lee, SM; Leung, CH; Li, D; Li, G; Li, P; Li, S; Lin, L; Ma, DL; Wang, W; Wu, C | 1 |
| He, L; Luo, J; Wang, Y | 1 |
| Huang, X; Jin, X; Liu, P; Tang, J; Wang, Y; Wu, G; Xu, Y; Zhang, D | 1 |
| Amé, JC; Dantzer, F; Hanini, N; Nguekeu-Zebaze, L; Noll, A; Roegel, L; Wadier, N | 1 |
| Abousaida, B; Carter, R; Derry, P; Gonzalez, VV; Kim, JBK; Krishnan, S; Liopo, AV; Mackeyev, Y; Rauta, PR; Sanders, K; Shohayeb, MA; Singh, P; Tezcan, O; Vijay, GV; Zahra, Y; Zubarev, ER | 1 |
| Cheng, X; Gong, T; Li, S; Qi, J; Song, X; Xin, W; Xing, Y; Yang, J; Zhang, J; Zhao, C; Zhao, X; Zheng, X; Zhu, D | 1 |
| Fu, X; Li, J; Li, T; Shang, W; Wang, J; Wang, X; Zhang, L | 1 |
| Batie, M; Fasanya, T; Kenneth, NS; Rocha, S | 1 |
| Li, L; Song, Y; Xi, Y | 1 |
| Becker, L; Cui, C; Czyz, D; Dai, L; Ding, J; He, M; Hu, R; Huang, H; Kim, S; Lee, S; Liu, W; Perez-Neut, M; Ren, B; Roeder, RG; Shuman, HA; Tang, Z; Weng, Y; Ye, Z; Zhang, D; Zhao, Y; Zheng, YG; Zhou, G | 1 |
| Adhikary, H; Biggar, KK; Chopra, A; Willmore, WG | 1 |
| Biggar, KK | 1 |
| Storey, KB; Wijenayake, S | 1 |
| Bi, J; Liu, J; Qian, X; Wang, H; Wang, Y; Yu, H; Zhang, X | 1 |
| Agrawal, A; Rathor, R; Suryakumar, G | 1 |
| Concepción-Román, S; Jia, X; Liu, Q; Long, D; Maina, PK; Marin, M; Qi, HH; Shao, P; Umesalma, S | 1 |
| Chen, R; Deng, R; Hou, G; Jiang, B; Wang, Y; Xu, M; Yu, J; Yuan, H; Zhang, H; Zhao, X | 1 |
| Hawkins, LJ; Storey, KB; Wijenayake, S | 1 |
| Liu, H; Luo, Y; Wang, Q; Wang, Y; Yang, Y; Zhang, Y | 1 |
| Duan, X; Guo, X; Shen, Y; Tian, Z; Yao, L | 1 |
| Chun, YS; Park, JW; Shin, DH; Shin, SH; Yoon, H | 1 |
| Dunne, K; Flashman, E; Hancock, RL; Kawamura, A; Walport, LJ | 1 |
| Ang, SY; Bruneau, BG; Ge, K; Huang, Y; Lee, JE; Spencer, CI; Uebersohn, A | 1 |
| Cheng, R; Hu, B; Kong, F; Liu, X; Pan, X; Tang, B; Xu, K | 1 |
| Au, DW; Chan, TF; Chiu, JM; Kong, RY; Lai, KP; Lau, K; Li, JW; Tong, Y; Tse, AC; Wang, SY; Wong, AS; Wong, CK; Wu, RS; Zhang, JW | 1 |
| Abelanet, A; Chia, GS; Doedens, A; Evans, CE; Goldrath, AW; Griffiths, JR; Johnson, RS; Lee, KL; Macias, D; Palazon, A; Phan, AT; Poellinger, L; Sim, J; Tyrakis, PA; Veliça, P; You, J | 1 |
| Beyer, S; Jensen, KS; Johansen, JV; Kristensen, MM; Staller, P | 1 |
| Almac, E; Bezemer, R; Ince, C; Johannes, T; Kandil, A; Legrand, M; Mik, EG; Payen, D | 1 |
| Cai, Q; Kumar, P; Ma, M; Robertson, ES; Verma, SC | 1 |
| Le, W; Li, J; Li, T; Tang, Y; Wang, Z; Yang, D; Zhang, X | 1 |
| Beer, TM; Geng, H; Harvey, CT; Liu, Q; Pittsenbarger, J; Qian, DZ; Xue, C | 1 |
| Branco, LG; De Paula, PM; Paro, FM; Steiner, AA | 1 |
| Babal, P; Gillespie, MN; Olson, JW; Ruchko, M; Weeks, RS | 1 |
| HEYWOOD, JD; KARON, M; WEISSMAN, S | 1 |
| Dooley, CT; Dore, TM; Hanson, GT; Jackson, WC; Remington, SJ; Tsien, RY | 1 |
| Fischer, LG; Freise, H; Hilpert, JH; Lauer, S; Sielenkämper, AW; Van Aken, H; Wendholt, D | 1 |
| Kentsis, A; Miller, F; Osman, R; Pan, ZQ | 1 |
| Busch, C; Cornelissen, AJ; Gebhard, MM; Martin, EO; Motsch, J; Spöhr, F; Weimann, J | 1 |
| Banasová, A; Bíbová, J; Hampl, V; Herget, J; Hnilicková, O; Lachmanová, V; Miková, D; Uhlík, J | 1 |
| Belinka, B; Lu, SE; Pachence, J; Poiani, GJ; Riley, DJ; Simon, PM; Tozzi, CA | 1 |
| Bartus, JB; Chlopicki, S; Walski, M | 1 |
| Dayal, M; Frydman, J; Giffard, RG; Ouyang, YB; Sun, Y; Xu, L; Yang, CF | 1 |
| Bellini, C; Campone, F; Serra, G | 1 |
| Bloch, KD; Buys, ES; Evgenov, OV; Graveline, AR; Hotta, Y; Ichinose, F; Liu, R; Zapol, WM | 1 |
| Izuhara, Y; Miyata, T; Nangaku, M; Ohtomo, S; Strihou, Cv; Takizawa, S | 1 |
| Allain, H; Lacroix, P; Le Pollès, JB; Linée, P; Pape, D; Reymann, JM; Van den Driessche, J | 1 |
| Burgoyne, RD; Gross, J; Rose, SP | 1 |
| Chicoine, LG; Earley, S; O'Donaughy, TL; Resta, TC; Walker, BR | 1 |
| McMurtry, IF; Rodman, DM; Sato, K | 1 |
| Bao-Shan, KU; Hong-Ping, G | 1 |
| Billiar, TR; Carcillo, JA; Carlos, TM; Chen, M; Clark, RS; DeKosky, ST; Dixon, CE; Kochanek, PM; Marion, DW; Schiding, JK; Sinz, EH; Watkins, SC; Williams, D; Wisniewski, SR | 1 |
| Ben-Ari, Y; Chevassus-Au-Louis, N; Diabira, D; Gozlan, H; Hennou, S | 1 |
| Fischer, LG; Hahnenkamp, K; Horstman, DJ; Kechner, NE; Rich, GF | 1 |
| Gonzales, RJ; Walker, BR | 1 |
| Anttinen, H; Kivirikko, KI; Oikarinen, A | 1 |
| Hearse, DJ; Oratz, M; Rothschild, MA; Schreiber, SS | 1 |
| Coeugniet, E | 1 |
| Evans, C; Oratz, M; Reff, F; Rothschild, MA; Schreiber, SS | 1 |
| Oratz, M; Rothschild, MA; Schreiber, SS | 1 |
| Carter, AJ; Müller, RE | 1 |
| Brux, B; Gross, J | 1 |
| Prockop, DJ; Uitto, J | 1 |
| Arnfred, T; Hertz, L | 1 |
4 review(s) available for lysine and Hypoxia
| Article | Year |
|---|---|
Oxygen-regulated post-translation modifications as master signalling pathway in cells.
Topics: Animals; Chromatin; Humans; Hypoxia; Lysine; Mammals; Oxygen; Protein Processing, Post-Translational | 2023 |
Insights into The Function and Regulation of Jumonji C Lysine Demethylases as Hypoxic Responsive Enzymes.
Topics: Biocatalysis; Chromosomal Proteins, Non-Histone; Histone Demethylases; Histones; Humans; Hypoxia; Hypoxia-Inducible Factor 1, alpha Subunit; Jumonji Domain-Containing Histone Demethylases; Kinetics; Lysine; Methylation; Oxygen; Prolyl Hydroxylases; Protein Processing, Post-Translational; Signal Transduction | 2020 |
Protein lysine methylation in the regulation of anoxia tolerance in the red eared slider turtle, Trachemys scripta elegans.
Topics: Adaptation, Physiological; Animals; Gene Expression Regulation; Hypoxia; Lysine; Methylation; Protein Processing, Post-Translational; Turtles | 2020 |
Epigenetic regulation by histone demethylases in hypoxia.
Topics: Cardiovascular Diseases; Epigenesis, Genetic; Histones; Humans; Hypoxia; Jumonji Domain-Containing Histone Demethylases; Lysine; Methylation; Models, Genetic; Neoplasms | 2015 |
63 other study(ies) available for lysine and Hypoxia
| Article | Year |
|---|---|
Hypoxia-activated KDAC inhibitor: Taking a breath from untargeted therapy.
Topics: Animals; Histone Deacetylases; Hypoxia; Lysine; Neoplasms; Prodrugs | 2021 |
EGLN1 prolyl hydroxylation of hypoxia-induced transcription factor HIF1α is repressed by SET7-catalyzed lysine methylation.
Topics: Animals; Catalysis; Histone-Lysine N-Methyltransferase; Humans; Hydroxylation; Hypoxia; Hypoxia-Inducible Factor 1, alpha Subunit; Hypoxia-Inducible Factor-Proline Dioxygenases; Lysine; Methylation; Oxygen; Protein Processing, Post-Translational | 2022 |
A "short-cut" response of autophagy to oxidative stress: oxygen-dependent activity of a lysine demethylase guides the activity of ULK1 during hypoxia.
Topics: Autophagy; Autophagy-Related Protein-1 Homolog; Humans; Hypoxia; Intracellular Signaling Peptides and Proteins; Lysine; Oxidative Stress; Oxygen; Phosphorylation; Protein-Arginine N-Methyltransferases | 2022 |
Hypoxic condition induced H3K27me3 modification of the LncRNA Tmem235 promoter thus supporting apoptosis of BMSCs.
Topics: Apoptosis; Enhancer of Zeste Homolog 2 Protein; Histone Demethylases; Histones; Humans; Hypoxia; Hypoxia-Inducible Factor 1, alpha Subunit; Lysine; Mesenchymal Stem Cells; Promoter Regions, Genetic; RNA, Long Noncoding | 2022 |
Homocysteine-targeting compounds as a new treatment strategy for diabetic wounds via inhibition of the histone methyltransferase SET7/9.
Topics: Animals; Diabetes Mellitus; Histone Methyltransferases; Homocysteine; Hyperglycemia; Hypoxia; Hypoxia-Inducible Factor 1, alpha Subunit; Lysine; Mice; Neovascularization, Pathologic | 2022 |
Epigenetic modification mechanism of histone demethylase KDM1A in regulating cardiomyocyte apoptosis after myocardial ischemia-reperfusion injury.
Topics: Apoptosis; Epigenesis, Genetic; Histone Demethylases; Humans; Hypoxia; Lysine; Myocardial Reperfusion Injury; Myocytes, Cardiac | 2022 |
Global crotonylome reveals hypoxia-mediated lamin A crotonylation regulated by HDAC6 in liver cancer.
Topics: Histone Deacetylase 6; Histones; Humans; Hypoxia; Lamin Type A; Liver Neoplasms; Lysine; Protein Processing, Post-Translational | 2022 |
PARP3 supervises G9a-mediated repression of adhesion and hypoxia-responsive genes in glioblastoma cells.
Topics: Basic Helix-Loop-Helix Transcription Factors; Brain Neoplasms; Cell Cycle Proteins; Complement C9; Glioblastoma; Histones; Humans; Hypoxia; Lysine; Methyltransferases; Poly(ADP-ribose) Polymerases; Tumor Suppressor Proteins | 2022 |
Pancreatic tumor microenvironmental acidosis and hypoxia transform gold nanorods into cell-penetrant particles for potent radiosensitization.
Topics: Acidosis; Animals; Cell Line, Tumor; Glutamic Acid; Gold; Hypoxia; Lysine; Mice; Nanotubes; Neoplasms; Tumor Microenvironment | 2022 |
Circ-myh8 Promotes Pulmonary Hypertension by Recruiting KAT7 to Govern Hypoxia-Inducible Factor-1α Expression.
Topics: Animals; Cell Proliferation; Histone Acetyltransferases; Histones; Hypertension, Pulmonary; Hypoxia; Hypoxia-Inducible Factor 1, alpha Subunit; Lysine; Mice; Myosin Heavy Chains; RNA, Circular; RNA, Small Interfering | 2023 |
Mechanism of NURP1 in temozolomide resistance in hypoxia-treated glioma cells via the KDM3A/TFEB axis.
Topics: Animals; Autophagy; Basic Helix-Loop-Helix Leucine Zipper Transcription Factors; Disease Models, Animal; Glioma; Humans; Hypoxia; Jumonji Domain-Containing Histone Demethylases; Lysine; Nuclear Proteins; Temozolomide | 2023 |
Lysine demethylase 3A in hypoxic macrophages promotes ovarian cancer development through regulation of the vascular endothelial growth factor A/Akt signaling.
Topics: Cell Adhesion Molecules; Cell Line, Tumor; Female; Humans; Hypoxia; Jumonji Domain-Containing Histone Demethylases; Lysine; Macrophages; Ovarian Neoplasms; Proto-Oncogene Proteins c-akt; Signal Transduction; Tumor Microenvironment; Vascular Endothelial Growth Factor A | 2023 |
Metabolic regulation of gene expression by histone lactylation.
Topics: Acetylation; Amino Acid Sequence; Animals; Cell Line, Tumor; Chromatin; Epigenesis, Genetic; Glycolysis; Histones; Homeostasis; Humans; Hypoxia; Lactic Acid; Lysine; Macrophages; Male; Mice; Mice, Inbred C57BL; Reproducibility of Results; Transcription, Genetic | 2019 |
Dynamic regulation of histone H3 lysine (K) acetylation and deacetylation during prolonged oxygen deprivation in a champion anaerobe.
Topics: Acetylation; Animals; Chromatin; Epigenesis, Genetic; Gene Expression Regulation; Histone Acetyltransferases; Histones; Hypoxia; Lysine; Oxygen; Protein Processing, Post-Translational; Sirtuins; Turtles | 2020 |
Modulation of Central Carbon Metabolism by Acetylation of Isocitrate Lyase in Mycobacterium tuberculosis.
Topics: Acetylation; Carbon; Energy Metabolism; Fatty Acids; Hypoxia; Isocitrate Lyase; Lysine; Mycobacterium tuberculosis; Phenotype; Transcription, Genetic | 2017 |
Oxidative protein modification alters proteostasis under acute hypobaric hypoxia in skeletal muscles: a comprehensive in vivo study.
Topics: Animals; Antioxidants; Calcium; Caspase 3; CCAAT-Enhancer-Binding Proteins; Chaperonin 60; Endoplasmic Reticulum Chaperone BiP; Heat-Shock Proteins; HSP70 Heat-Shock Proteins; Hypoxia; Lysine; Male; Malondialdehyde; Muscle Proteins; Muscle, Skeletal; Oxidative Stress; Protein Processing, Post-Translational; Proteostasis; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species | 2017 |
Histone demethylase PHF8 regulates hypoxia signaling through HIF1α and H3K4me3.
Topics: Basic Helix-Loop-Helix Transcription Factors; Cell Line; Cell Proliferation; Clustered Regularly Interspaced Short Palindromic Repeats; CRISPR-Cas Systems; Gene Expression Regulation; HEK293 Cells; Histone Demethylases; Histones; Humans; Hypoxia; Jumonji Domain-Containing Histone Demethylases; Lysine; Neuroendocrine Cells; Receptors, Androgen; RNA, Long Noncoding; Signal Transduction; Transcription Factors; Transcription, Genetic | 2017 |
SUMO1 modification of KHSRP regulates tumorigenesis by preventing the TL-G-Rich miRNA biogenesis.
Topics: Base Composition; Carcinogenesis; Cell Line, Tumor; Disease Progression; Humans; Hydrogen Peroxide; Hypoxia; Lysine; MicroRNAs; Models, Biological; Nucleic Acid Conformation; Protein Binding; Protein Transport; RNA-Binding Proteins; SUMO-1 Protein; Sumoylation; Terminal Repeat Sequences; Trans-Activators | 2017 |
Dynamic regulation of six histone H3 lysine (K) methyltransferases in response to prolonged anoxia exposure in a freshwater turtle.
Topics: Animals; Fresh Water; Gene Expression Regulation; Histone Methyltransferases; Histone-Lysine N-Methyltransferase; Histones; Hypoxia; Liver; Lysine; Methylation; Methyltransferases; Oxygen; Protein Processing, Post-Translational; Turtles | 2018 |
Effect of deubiquitinase USP8 on hypoxia/reoxygenation‑induced inflammation by deubiquitination of TAK1 in renal tubular epithelial cells.
Topics: Animals; Endopeptidases; Endosomal Sorting Complexes Required for Transport; Epithelial Cells; Gene Silencing; Humans; Hypoxia; Inflammation; Kidney Tubules; Lysine; MAP Kinase Kinase Kinases; Mice; NF-kappa B; Oxygen; Ubiquitin Thiolesterase; Ubiquitination | 2018 |
Histone H3K9 demethylase JMJD1A is a co-activator of erythropoietin expression under hypoxia.
Topics: Animals; Basic Helix-Loop-Helix Transcription Factors; Biocatalysis; Erythropoietin; Gene Expression Regulation; Hep G2 Cells; Histones; Humans; Hypoxia; Jumonji Domain-Containing Histone Demethylases; Lysine; Male; Methylation; Mice; Mice, Inbred C57BL; Transcription, Genetic | 2019 |
Differential roles of Sirt1 in HIF-1α and HIF-2α mediated hypoxic responses.
Topics: Acetylation; Amino Acid Sequence; Base Sequence; Basic Helix-Loop-Helix Transcription Factors; Binding Sites; Cell Hypoxia; Cell Line, Tumor; Cell Proliferation; Gene Knockdown Techniques; HCT116 Cells; HEK293 Cells; HeLa Cells; Hep G2 Cells; Humans; Hypoxia; Hypoxia-Inducible Factor 1, alpha Subunit; Lysine; Molecular Sequence Data; Neoplasms; RNA, Small Interfering; Sirtuin 1 | 2014 |
KMT2D regulates specific programs in heart development via histone H3 lysine 4 di-methylation.
Topics: Animals; Aorta; Cell Cycle; Echocardiography; Electrophysiology; Enhancer Elements, Genetic; Female; Gene Deletion; Gene Expression Profiling; Gene Expression Regulation, Developmental; Heart; Heart Ventricles; Histone-Lysine N-Methyltransferase; Histones; Hypoxia; Lysine; Methylation; Mice; Microscopy, Fluorescence; Myeloid-Lymphoid Leukemia Protein; Myocardium; Myocytes, Cardiac; Oxygen; Promoter Regions, Genetic; Sequence Analysis, RNA | 2016 |
Simultaneous fluorescence imaging of selenol and hydrogen peroxide under normoxia and hypoxia in HepG2 cells and in vivo.
Topics: Fluorescence; Fluorescent Dyes; Gold; Hep G2 Cells; Humans; Hydrogen Peroxide; Hypoxia; Lysine; Metal Nanoparticles; Peptides; Selenium Compounds; Spectrometry, Fluorescence | 2016 |
Hypoxia causes transgenerational impairments in reproduction of fish.
Topics: Animals; Epigenesis, Genetic; Fish Proteins; Histones; Hypoxia; Lysine; Male; Oryzias; Proteomics; Reproduction; Testis; Transcriptome | 2016 |
S-2-hydroxyglutarate regulates CD8
Topics: Animals; CD8-Positive T-Lymphocytes; Cell Differentiation; Dioxygenases; DNA; DNA Methylation; Glutarates; Histones; Homeostasis; Hypoxia; Hypoxia-Inducible Factor 1, alpha Subunit; Ketoglutaric Acids; Lymphocyte Activation; Lysine; Mice; Oxygen; Protein Stability; Receptors, Antigen, T-Cell; Von Hippel-Lindau Tumor Suppressor Protein | 2016 |
The histone demethylases JMJD1A and JMJD2B are transcriptional targets of hypoxia-inducible factor HIF.
Topics: Arginine; Base Sequence; Gene Expression Regulation; HeLa Cells; Histone Deacetylases; Histones; Humans; Hypoxia; Hypoxia-Inducible Factor 1; Jumonji Domain-Containing Histone Demethylases; Kidney; Lysine; Microscopy, Fluorescence; Molecular Sequence Data; Oxidoreductases, N-Demethylating; Transcription Factors | 2008 |
L-NIL prevents renal microvascular hypoxia and increase of renal oxygen consumption after ischemia-reperfusion in rats.
Topics: Animals; Enzyme Inhibitors; Hypoxia; Kidney; Lysine; Microcirculation; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase Type II; Oxygen Consumption; Peroxidase; Rats; Rats, Sprague-Dawley; Renal Circulation; Reperfusion Injury; Sodium | 2009 |
Hypoxia inactivates the VHL tumor suppressor through PIASy-mediated SUMO modification.
Topics: Binding Sites; Cell Line; Cell Line, Tumor; Humans; Hypoxia; Hypoxia-Inducible Factor 1, alpha Subunit; Lysine; Models, Biological; Poly-ADP-Ribose Binding Proteins; Protein Inhibitors of Activated STAT; Protein Isoforms; Protein Structure, Tertiary; RNA, Small Interfering; Small Ubiquitin-Related Modifier Proteins; Up-Regulation; Von Hippel-Lindau Tumor Suppressor Protein | 2010 |
Hypoxia-induced down-regulation of neprilysin by histone modification in mouse primary cortical and hippocampal neurons.
Topics: Animals; Astrocytes; Cerebral Cortex; DNA Methylation; Down-Regulation; Epigenesis, Genetic; Gene Expression Regulation; Hippocampus; Histone Deacetylases; Histones; Hypoxia; Lysine; Mice; Neprilysin; Polymerase Chain Reaction; Promoter Regions, Genetic; RNA, Messenger; RNA, Small Interfering; Valproic Acid | 2011 |
HDAC4 protein regulates HIF1α protein lysine acetylation and cancer cell response to hypoxia.
Topics: Acetylation; Cell Line, Tumor; Cycloheximide; Gene Expression Regulation, Neoplastic; Genes, Reporter; Glycolysis; HEK293 Cells; Histone Deacetylases; Humans; Hypoxia; Hypoxia-Inducible Factor 1, alpha Subunit; Lysine; Mutation; Protein Synthesis Inhibitors; Repressor Proteins; RNA, Small Interfering | 2011 |
Central heme oxygenase-carbon monoxide pathway in the control of breathing under normoxia and hypoxia.
Topics: Animals; Carbon Monoxide; Deuteroporphyrins; Enzyme Inhibitors; Heme; Heme Oxygenase (Decyclizing); Hypoxia; Injections, Intraventricular; Lysine; Male; Rats; Rats, Wistar; Respiration; Tidal Volume; Time Factors; Ventilation | 2002 |
Putrescine transport in hypoxic rat main PASMCs is required for p38 MAP kinase activation.
Topics: Animals; Binding, Competitive; Biological Transport; Cycloheximide; Dactinomycin; Enzyme Activation; Hypoxia; Lysine; Male; Mitogen-Activated Protein Kinases; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Polyamines; Pulmonary Artery; Putrescine; Rats; Rats, Sprague-Dawley; Sodium; Spermine; Time Factors | 2003 |
STUDIES OF IN VITRO SYNTHESIS OF HETEROGENIC HEMOGLOBINS.
Topics: Blood Protein Electrophoresis; Bloodletting; Bone Marrow; Carbon Isotopes; Carbon Monoxide; Chromatography; Hemoglobins; Hemoglobins, Abnormal; Hypoxia; In Vitro Techniques; Iron; Leucine; Lysine; Metabolism; Reticulocytes; Valine | 1964 |
Imaging dynamic redox changes in mammalian cells with green fluorescent protein indicators.
Topics: Cloning, Molecular; Dose-Response Relationship, Drug; Epidermal Growth Factor; Flow Cytometry; Glutathione; Glutathione Disulfide; Green Fluorescent Proteins; HeLa Cells; HL-60 Cells; Humans; Hydrogen Peroxide; Hypoxia; Luminescent Proteins; Lysine; Lysophospholipids; Magnetic Resonance Spectroscopy; Mutation; Oxidants; Oxidation-Reduction; Oxygen; Spectrometry, Fluorescence; Superoxides; Time Factors; Xanthine Oxidase | 2004 |
Modulation of hypoxic pulmonary vasoconstriction is time and nitric oxide dependent in a peritonitis model of sepsis.
Topics: Angiotensin II; Animals; Blood Pressure; Blotting, Western; Enzyme Inhibitors; Hypoxia; In Vitro Techniques; Lung; Lysine; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Peritonitis; Prospective Studies; Pulmonary Artery; Rats; Rats, Sprague-Dawley; Sepsis; Time Factors; Vasoconstriction | 2004 |
Inactivation of VHL by tumorigenic mutations that disrupt dynamic coupling of the pVHL.hypoxia-inducible transcription factor-1alpha complex.
Topics: Actins; Anaphase-Promoting Complex-Cyclosome; Antibodies, Monoclonal; Basic Helix-Loop-Helix Transcription Factors; Cell Line; Cell Line, Tumor; Dose-Response Relationship, Drug; Electrophoresis, Polyacrylamide Gel; Glutathione Transferase; Humans; Hydroxylation; Hypoxia; Hypoxia-Inducible Factor 1, alpha Subunit; Leucine; Lysine; Models, Molecular; Mutation; Mutation, Missense; Neoplasms; Peptides; Plasmids; Proline; Protein Binding; Protein Conformation; Protein Structure, Secondary; Protein Structure, Tertiary; Serine; Time Factors; Trans-Activators; Transcription Factors; Tumor Suppressor Proteins; Ubiquitin; Ubiquitin-Protein Ligase Complexes; Ubiquitin-Protein Ligases; Von Hippel-Lindau Tumor Suppressor Protein | 2005 |
Role of endogenous nitric oxide in endotoxin-induced alteration of hypoxic pulmonary vasoconstriction in mice.
Topics: Animals; Endotoxins; Enzyme Inhibitors; Hypoxia; Lipopolysaccharides; Lysine; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Pulmonary Circulation; Respiration; Vasoconstriction | 2005 |
Pulmonary vascular iNOS induction participates in the onset of chronic hypoxic pulmonary hypertension.
Topics: Administration, Oral; Animals; Chronic Disease; Dose-Response Relationship, Drug; Enzyme Inhibitors; Exhalation; Hypertension, Pulmonary; Hypoxia; Lung; Lysine; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase Type II; Pulmonary Artery; Rats; Rats, Wistar; Time Factors; Tyrosine | 2006 |
Prodrug of proline analogue reduces hypoxic pulmonary hypertension in rats.
Topics: Animals; Blood Pressure; Dose-Response Relationship, Drug; Hydroxyproline; Hypertension, Pulmonary; Hypoxia; Infusion Pumps; Injections, Intravenous; Injections, Spinal; Injections, Subcutaneous; Lysine; Male; Polyethylene Glycols; Prodrugs; Proline; Pulmonary Artery; Rats; Rats, Sprague-Dawley; Time Factors; Treatment Outcome | 2006 |
Ultrastructure of immediate microvascular lung injury induced by bacterial endotoxin in the isolated, no-deficient lung perfused with full blood.
Topics: Animals; Bacterial Infections; Blood Pressure; Blood-Air Barrier; Disease Models, Animal; Endothelium, Vascular; Enzyme Inhibitors; Hypoxia; In Vitro Techniques; Lipopolysaccharides; Lung; Lysine; Microcirculation; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Organ Size; Perfusion; Pulmonary Circulation; Pulmonary Edema; Rats; Rats, Wistar; Tidal Volume; Vasoconstriction; Venous Pressure | 2005 |
Chaperonin GroEL and its mutant D87K protect from ischemia in vivo and in vitro.
Topics: Analysis of Variance; Animals; Animals, Newborn; Aspartic Acid; Astrocytes; Blotting, Western; Brain; Cell Aggregation; Cell Count; Cell Death; Cells, Cultured; Chaperonin 60; Cricetinae; Cricetulus; Fluorescent Antibody Technique; Glial Fibrillary Acidic Protein; Glucose; Hot Temperature; Hypoxia; In Vitro Techniques; Infarction, Middle Cerebral Artery; Ischemia; Lysine; Mice; Microtubule-Associated Proteins; Mutation; Neurons; Tetrazolium Salts; Time Factors; Transfection | 2006 |
Pulmonary hypertension following L-lysine ibuprofen therapy in a preterm infant with patent ductus arteriosus.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Ductus Arteriosus, Patent; Fatal Outcome; Humans; Hypertension, Pulmonary; Hypoxia; Ibuprofen; Infant, Newborn; Infant, Premature; Infant, Premature, Diseases; Lysine | 2006 |
Congenital NOS2 deficiency prevents impairment of hypoxic pulmonary vasoconstriction in murine ventilator-induced lung injury.
Topics: Animals; Bronchoconstriction; Enzyme Inhibitors; Hypoxia; Lung; Lysine; Male; Mice; Mice, Inbred C57BL; Nitric Oxide Synthase Type II; Pulmonary Artery; Pulmonary Ventilation; Respiratory Distress Syndrome; Respiratory Insufficiency; Vascular Resistance; Vasoconstriction; Ventilators, Mechanical | 2007 |
Cobalt ameliorates renal injury in an obese, hypertensive type 2 diabetes rat model.
Topics: Animals; Antimutagenic Agents; Arginine; Basic Helix-Loop-Helix Transcription Factors; Blood Pressure; Blotting, Western; Chromatography, High Pressure Liquid; Cobalt; Connective Tissue Growth Factor; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Disease Progression; Gene Expression; Glycation End Products, Advanced; Hypertension; Hypoxia; Hypoxia-Inducible Factor 1, alpha Subunit; Immediate-Early Proteins; Insulin-Like Growth Factor Binding Proteins; Intercellular Signaling Peptides and Proteins; Kidney; Lysine; Male; NADPH Oxidases; Obesity; Oxidative Stress; Polymerase Chain Reaction; Rats; Rats, Inbred SHR; RNA, Messenger; Transforming Growth Factor beta | 2008 |
[Effect of ascorbic acid during acute iterative anoxia, hypothesis of an anti-oxidizing mechanism of action in comparison with the effect of hydroquinone].
Topics: Animals; Ascorbic Acid; Aspirin; Brain; Electroencephalography; Hydroquinones; Hypoxia; Lysine; Rats | 1980 |
Influence of prenatal hypoxia on brain development: effects on body weight, brain weight, DNA, protein, acetylcholinesterase, 3-quinuclidinyl benzilate binding, and in vivo incorporation of [14C]lysine into subcellular fractions.
Topics: Acetylcholinesterase; Aging; Animals; Body Weight; Brain; DNA; Female; Fetal Diseases; Fetus; Hypoxia; Lysine; Nerve Tissue Proteins; Organ Size; Pregnancy; Quinuclidines; Quinuclidinyl Benzilate; Rats; Subcellular Fractions | 1981 |
Unaltered vasoconstrictor responsiveness after iNOS inhibition in lungs from chronically hypoxic rats.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Animals; Chronic Disease; Enzyme Inhibitors; Hemodynamics; Hypoxia; In Vitro Techniques; Lipopolysaccharides; Lung; Lysine; Male; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitroarginine; Pulmonary Circulation; Rats; Rats, Sprague-Dawley; Vascular Resistance; Vasoconstriction; Vasoconstrictor Agents | 1999 |
Hypoxia inhibits increased ETB receptor-mediated NO synthesis in hypertensive rat lungs.
Topics: Animals; Arginine; Biopterins; Egtazic Acid; Enzyme Inhibitors; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; Hypoxia; In Vitro Techniques; Luminescent Measurements; Lung; Lysine; Male; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Rats; Rats, Sprague-Dawley; Receptor, Endothelin B; Receptors, Endothelin; Time Factors | 1999 |
Neuroprotective effect of L-lysine monohydrochloride on acute iterative anoxia in rats with quantitative analysis of electrocorticogram.
Topics: Animals; Electrocardiography; Hypoxia; Lysine; Male; Neuroprotective Agents; Rats; Rats, Inbred SHR; Rats, Wistar; Somatosensory Cortex | 1999 |
Inducible nitric oxide synthase is an endogenous neuroprotectant after traumatic brain injury in rats and mice.
Topics: Animals; Brain Damage, Chronic; Brain Injuries; Cognition Disorders; Enzyme Induction; Enzyme Inhibitors; Guanidines; Hippocampus; Hypoxia; Lysine; Male; Maze Learning; Mice; Mice, Knockout; Nerve Tissue Proteins; Neurons; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Polymerase Chain Reaction; Radiation Injuries, Experimental; Rats; Rats, Sprague-Dawley; Whole-Body Irradiation; Wounds, Nonpenetrating | 1999 |
Late embryonic expression of AMPA receptor function in the CA1 region of the intact hippocampus in vitro.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Afferent Pathways; Aging; Animals; Animals, Newborn; Benzodiazepines; Bicuculline; Cations, Divalent; Electric Stimulation; Embryonic and Fetal Development; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Fluorescent Dyes; Hippocampus; Hypoxia; Lysine; Pyramidal Cells; Quinoxalines; Rats; Rats, Wistar; Receptors, AMPA; Synapses; Tetrodotoxin | 1999 |
Selective iNOS inhibition attenuates acetylcholine- and bradykinin-induced vasoconstriction in lipopolysaccharide-exposed rat lungs.
Topics: Acetylcholine; Animals; Bradykinin; Dexamethasone; Enzyme Inhibitors; Hypoxia; In Vitro Techniques; Lipopolysaccharides; Lung; Lysine; Male; Muscarinic Antagonists; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitroprusside; Piperidines; Pulmonary Circulation; Rats; Rats, Sprague-Dawley; Salmonella typhimurium; Vasoconstriction | 1999 |
Role of CO in attenuated vasoconstrictor reactivity of mesenteric resistance arteries after chronic hypoxia.
Topics: Animals; Blood Pressure; Carbon Monoxide; Heme; Hypoxia; Lysine; Male; Mesenteric Arteries; Nitric Oxide; Nitroarginine; Phenylephrine; Rats; Rats, Sprague-Dawley; Reference Values; Vascular Resistance; Vasoconstriction; Vasodilator Agents | 2002 |
Further studies on the effect of the collagen triple-helix formation on the hydroxylation of lysine and the glycosylations of hydroxylysine in chick-embryo tendon and cartilage cells.
Topics: Animals; Cartilage; Chick Embryo; Collagen; Dithiothreitol; Hydroxylation; Hydroxylysine; Hydroxyproline; Hypoxia; Lysine; Proline; Tendons | 1977 |
Protein synthesis in prolonged cardiac arrest.
Topics: Adenosine Triphosphate; Animals; Coronary Circulation; Glycogen; Guinea Pigs; Heart Arrest; Heart Arrest, Induced; Hypoxia; Lactates; Lysine; Male; Myocardial Contraction; Potassium; Protein Biosynthesis | 1977 |
Drugs with antithrombotic effect: experimental study.
Topics: Animals; Aspirin; Dipyridamole; Drug Synergism; Heparin; Hypoxia; Lysine; Mice; Platelet Aggregation; Promethazine; Rats; Thromboembolism | 1976 |
The effect of pressure or flow stress on right ventricular protein synthesis in the face of constant and restricted coronary perfusion.
Topics: Adenosine Triphosphate; Albumins; Animals; Blood Pressure; Carbon Radioisotopes; Cardiac Volume; Coronary Circulation; Guinea Pigs; Heart Ventricles; Hypoxia; Iodine Radioisotopes; Lactates; Lysine; Male; Models, Biological; Muscle Proteins; Perfusion; Pressure; Stress, Physiological | 1975 |
Pressure versus flow stress: the response of cardiac protein synthesis.
Topics: Adenosine Triphosphate; Animals; Cardiac Volume; Guinea Pigs; Heart Atria; Heart Diseases; Heart Ventricles; Hypertension; Hypoxia; Lysine; Male; Models, Biological; Muscle Proteins; Myocardial Contraction; Myocardium; Perfusion; Phenylalanine; Pressure; Stress, Physiological | 1975 |
Activation of excitatory amino acid receptors cannot alone account for anoxia-induced impairment of protein synthesis in rat hippocampal slices.
Topics: Animals; Aspartic Acid; Carbon Radioisotopes; Dizocilpine Maleate; Glutamates; Glutamic Acid; Hippocampus; Hypoxia; Kainic Acid; Lysine; Male; N-Methylaspartate; Nerve Tissue Proteins; Phenazocine; Phencyclidine; Quisqualic Acid; Rats; Receptors, Amino Acid; Receptors, Cell Surface; Receptors, N-Methyl-D-Aspartate | 1991 |
Uptake of lysine and incorporation into proteins of the cortex during a short-term hypoxia of neonatal rats.
Topics: Animals; Animals, Newborn; Brain; Cell Nucleus; Female; Hypoxia; Lysine; Male; Mitochondria; Protein Biosynthesis; Rats; Synaptic Membranes | 1991 |
Synthesis and secretion of under-hydroxylated procollagen at various temperatures by cells subject to temporary anoxia.
Topics: Animals; Carbon Radioisotopes; Cells, Cultured; Chick Embryo; Chromatography, Gel; Collagen; Cycloheximide; Electrophoresis, Polyacrylamide Gel; Hydroxylysine; Hypoxia; Isotope Labeling; Lysine; Mixed Function Oxygenases; Nitrogen; Proline; Protein Conformation; Protein Precursors; Temperature; Tendons; Time Factors | 1974 |
Effects of potassium and glutamate on brain cortex slices: uptake and release of glutamic and other amino acids.
Topics: Amino Acids; Aminobutyrates; Animals; Carbon Isotopes; Cerebral Cortex; Chromatography, Paper; Glutamates; Glutamine; Hypoxia; In Vitro Techniques; Leucine; Lysine; Potassium; Rats; Tritium; Water-Electrolyte Balance | 1971 |