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lysine and Huntington Disease

lysine has been researched along with Huntington Disease in 16 studies

Research

Studies (16)

TimeframeStudies, this research(%)All Research%
pre-19901 (6.25)18.7374
1990's0 (0.00)18.2507
2000's7 (43.75)29.6817
2010's6 (37.50)24.3611
2020's2 (12.50)2.80

Authors

AuthorsStudies
Bodai, L; Csont, T; Faragó, A; Farkas, A; Neller, A; Siági, F; Szabó, MR; Zsindely, N1
Boulos, A; Ciechanover, A; Cohen-Rosenzweig, C; Hakim-Eshed, V; Kwon, YT; Phuc Nguyen, HH; Riess, O; Yu-Taeger, L; Ziv, NE; Ziv, T1
Bezstarosti, K; Bury, AE; Demmers, JA; Guler, AT; Juenemann, K; Reits, EA; Sap, KA1
Bates, GP; Bodai, L; Finkbeiner, S; Fraenkel, E; Gipson, TA; Housman, DE; Krainc, D; Kratter, IH; Labadorf, A; Lau, A; Marsh, JL; Ng, CW; Ross, CA; Sadri-Vakili, G; Song, W; Thompson, LM; Troncosco, J; Vashishtha, M; Vogel-Ciernia, A; Yildirim, F1
Curtis, MA; Faull, RL; Kim, J; Nicholson, LF; Waldvogel, HJ1
Bajaj, N; Bedford, L; Cavey, JR; Layfield, R; Lowe, J; Mayer, RJ; Paine, S; Sheppard, PW; Thorpe, JR1
Barrow, RK; Mealer, RG; Sixt, KM; Snyder, SH; Subramaniam, S; Usiello, A1
Boo, JH; Han, D; Hwang, YJ; Kim, Y; Kowall, NW; Kwon, OK; Lee, J; Ryu, H; Todorova, K1
Bonner, A; Chen, JM; Cong, X; Czerwieniec, GA; DeGiacomo, F; Ellerby, LM; Gibson, BW; Held, JM; Schilling, B1
Agrawal, N; Cattaneo, E; Illes, K; Lukacsovich, T; Marsh, JL; Pallos, J; Pandolfi, PP; Rockabrand, E; Slepko, N; Steffan, JS; Thompson, LM; Trotman, LC; Zhu, YZ1
Beal, MF; Browne, S; D'Mello, S; Ferrante, RJ; Hewett, S; Kristal, BS; Kubilus, JK; Langley, B; Lee, J; Lu, P; Ratan, RR; Rubinsztein, DC; Ryu, H; Smith, K; Stavrovskaya, IG; Sugars, KL1
Baksi, K; Bhattacharyya, NP; Chattopadhyay, B; Mukhopadhyay, S1
Bates, GP; Becker, CH; Bennett, EJ; Kopito, RR; Ryu, KY; Schulman, H; Shaler, TA; Woodman, B; Zaitseva, TS1
Ahari, SE; Bahar, M; Banoei, MM; Houshmand, M; Kasraie, S; Moin, M; Panahi, MS; Shariati, P1
Blass, JP; Cooper, AJ; Folk, JE; Jeitner, TM; Matson, WR1
Arrieta, A; Bonilla, E; Prasad, AL1

Other Studies

16 other study(ies) available for lysine and Huntington Disease

ArticleYear
Acetylation State of Lysine 14 of Histone H3.3 Affects Mutant Huntingtin Induced Pathogenesis.
    International journal of molecular sciences, 2022, Dec-02, Volume: 23, Issue:23

    Topics: Acetylation; Animals; Drosophila; Histone Acetyltransferases; Histone Deacetylases; Histones; Huntington Disease; Lysine; Protein Processing, Post-Translational

2022
Site-specific ubiquitination of pathogenic huntingtin attenuates its deleterious effects.
    Proceedings of the National Academy of Sciences of the United States of America, 2020, 08-04, Volume: 117, Issue:31

    Topics: Animals; Brain; Cell Death; Cells, Cultured; Disease Models, Animal; Humans; Huntingtin Protein; Huntington Disease; Lysine; Neurons; Proteasome Endopeptidase Complex; Protein Aggregation, Pathological; Rats; Rats, Transgenic; Ubiquitination

2020
Global Proteome and Ubiquitinome Changes in the Soluble and Insoluble Fractions of Q175 Huntington Mice Brains.
    Molecular & cellular proteomics : MCP, 2019, Volume: 18, Issue:9

    Topics: Animals; Brain; Cell Membrane; Huntingtin Protein; Huntington Disease; Lysine; Mice, Mutant Strains; Proteome; Solubility; Ubiquitin; Ubiquitination; Workflow

2019
Targeting H3K4 trimethylation in Huntington disease.
    Proceedings of the National Academy of Sciences of the United States of America, 2013, Aug-06, Volume: 110, Issue:32

    Topics: Animals; Animals, Genetically Modified; Blotting, Western; Brain; Brain-Derived Neurotrophic Factor; Cells, Cultured; Drosophila melanogaster; Female; Gene Expression Profiling; Histone Demethylases; Histones; Humans; Huntingtin Protein; Huntington Disease; Lysine; Male; Methylation; Mice; Mice, Inbred C57BL; Mice, Inbred CBA; Nerve Tissue Proteins; Neurons; Oxidoreductases, N-Demethylating; Promoter Regions, Genetic; Reverse Transcriptase Polymerase Chain Reaction; RNA Interference

2013
The RAGE receptor and its ligands are highly expressed in astrocytes in a grade-dependant manner in the striatum and subependymal layer in Huntington's disease.
    Journal of neurochemistry, 2015, Volume: 134, Issue:5

    Topics: Adaptor Proteins, Signal Transducing; Aged; Aged, 80 and over; Astrocytes; Corpus Striatum; Ependyma; Female; Formins; Humans; Huntington Disease; Lysine; Male; MAP Kinase Signaling System; Microglia; Middle Aged; Nerve Tissue Proteins; Neurons; NF-kappa B; Receptor for Advanced Glycation End Products; Receptors, Immunologic; S100 Calcium Binding Protein beta Subunit; Severity of Illness Index

2015
Immunoreactivity to Lys63-linked polyubiquitin is a feature of neurodegeneration.
    Neuroscience letters, 2009, Sep-04, Volume: 460, Issue:3

    Topics: Alzheimer Disease; Animals; Brain; Humans; Huntington Disease; Immunohistochemistry; Lewy Bodies; Lysine; Mice; Neurodegenerative Diseases; Neurons; Parkinson Disease; Polyubiquitin; Proteasome Endopeptidase Complex

2009
Rhes, a physiologic regulator of sumoylation, enhances cross-sumoylation between the basic sumoylation enzymes E1 and Ubc9.
    The Journal of biological chemistry, 2010, Jul-02, Volume: 285, Issue:27

    Topics: Animals; Corpus Striatum; Cysteine; Glutamine; GTP-Binding Proteins; Humans; Huntington Disease; Lysine; Mice; Mice, Knockout; Mutation; Small Ubiquitin-Related Modifier Proteins; Ubiquitin-Conjugating Enzymes; Ubiquitin-Protein Ligases

2010
Dysregulation of upstream binding factor-1 acetylation at K352 is linked to impaired ribosomal DNA transcription in Huntington's disease.
    Cell death and differentiation, 2011, Volume: 18, Issue:11

    Topics: Acetylation; Animals; Cell Line; Chromatin Immunoprecipitation; CREB-Binding Protein; Disease Models, Animal; DNA, Ribosomal; Huntington Disease; Lysine; Male; Mice; Mice, Transgenic; Mutation; Pol1 Transcription Initiation Complex Proteins; Promoter Regions, Genetic; RNA Interference; RNA, Small Interfering; Transcription, Genetic

2011
Mass spectrometric identification of novel lysine acetylation sites in huntingtin.
    Molecular & cellular proteomics : MCP, 2011, Volume: 10, Issue:10

    Topics: Acetylation; Animals; Antibodies; Brain; Disease Progression; HEK293 Cells; Histone Deacetylase Inhibitors; Humans; Huntingtin Protein; Huntington Disease; Lysine; Mass Spectrometry; Mice; Nerve Tissue Proteins; Nuclear Proteins; Protein Processing, Post-Translational; Protein Structure, Tertiary

2011
SUMO modification of Huntingtin and Huntington's disease pathology.
    Science (New York, N.Y.), 2004, Apr-02, Volume: 304, Issue:5667

    Topics: Animals; Animals, Genetically Modified; Cell Line; Cell Nucleus; Corpus Striatum; Cytoplasm; Drosophila; Genes, MDR; HeLa Cells; Humans; Huntingtin Protein; Huntington Disease; Lysine; Mutation; Nerve Degeneration; Nerve Tissue Proteins; Neurons; Nuclear Proteins; Proline; Promoter Regions, Genetic; Rats; Recombinant Fusion Proteins; SUMO-1 Protein; Transcription, Genetic; Transfection; Ubiquitin

2004
Chemotherapy for the brain: the antitumor antibiotic mithramycin prolongs survival in a mouse model of Huntington's disease.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2004, Nov-17, Volume: 24, Issue:46

    Topics: Animals; Antibiotics, Antineoplastic; Brain; Cells, Cultured; Gene Silencing; Humans; Huntingtin Protein; Huntington Disease; In Vitro Techniques; Lysine; Male; Methylation; Mice; Mice, Transgenic; Mitochondria, Liver; Motor Activity; N-Methylaspartate; Nerve Tissue Proteins; Neurons; Nuclear Proteins; Plicamycin; Rats; Rats, Inbred BN; Rats, Inbred F344; Receptors, Glutamate; Transcription, Genetic

2004
Modulation of age at onset of Huntington disease patients by variations in TP53 and human caspase activated DNase (hCAD) genes.
    Neuroscience letters, 2005, Feb-10, Volume: 374, Issue:2

    Topics: Adolescent; Adult; Age of Onset; Aged; Aged, 80 and over; Arginine; Deoxyribonucleases; Female; Genetic Variation; Genotype; Glucan 1,3-beta-Glucosidase; Humans; Huntington Disease; Lysine; Male; Odds Ratio; Poly-ADP-Ribose Binding Proteins; Polymorphism, Single Nucleotide; Proline; Trinucleotide Repeat Expansion; Tumor Suppressor Protein p53

2005
Global changes to the ubiquitin system in Huntington's disease.
    Nature, 2007, Aug-09, Volume: 448, Issue:7154

    Topics: Animals; Brain; Disease Models, Animal; Humans; Huntington Disease; Inclusion Bodies; Lysine; Mice; Mice, Transgenic; Polyubiquitin; Proteasome Endopeptidase Complex; Ubiquitin

2007
Investigation of tRNA(Leu/Lys) and ATPase 6 genes mutations in Huntington's disease.
    Cellular and molecular neurobiology, 2008, Volume: 28, Issue:7

    Topics: Adenosine Triphosphatases; Amino Acid Substitution; DNA Damage; DNA Mutational Analysis; DNA, Mitochondrial; Genetic Predisposition to Disease; Genetic Testing; Humans; Huntington Disease; Leucine; Lysine; Mitochondrial Diseases; Mutation; RNA, Transfer

2008
Increased levels of gamma-glutamylamines in Huntington disease CSF.
    Journal of neurochemistry, 2008, Volume: 106, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Amination; Biogenic Polyamines; Biomarkers; Brain; Female; Glutamine; Humans; Huntington Disease; Lysine; Male; Middle Aged; Neurochemistry; Protein Processing, Post-Translational; Putrescine; Spermidine; Transglutaminases; Up-Regulation

2008
Huntington's disease: studies on brain free amino acids.
    Life sciences, 1988, Volume: 42, Issue:11

    Topics: Adult; Aged; Aged, 80 and over; Amino Acids; Aspartic Acid; Brain; Female; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Glycine; Histidine; Humans; Huntington Disease; Lysine; Male; Middle Aged; Putamen; Serine; Taurine

1988