Page last updated: 2024-08-17

lysine and Glial Cell Tumors

lysine has been researched along with Glial Cell Tumors in 61 studies

Research

Studies (61)

Timeframe	Studies, this research(%)	All Research%
pre-1990	1 (1.64)	18.7374
1990's	5 (8.20)	18.2507
2000's	7 (11.48)	29.6817
2010's	26 (42.62)	24.3611
2020's	22 (36.07)	2.80

Authors

Authors	Studies
Ayyannan, SR; Mitra, R	1
Gao, M; Ji, L; Li, M; Qiao, W; Song, Y; Su, P; Sun, L; Wang, X; Yang, X; Yi, B; Zhan, Y; Zhang, F; Zhang, R; Zhao, W	1
Bedekovics, J; Kurdi, N; Mehes, G; Mokanszki, A	1
Alejo, S; Brenner, AJ; Chen, Y; Clarke, K; Gilbert, AR; He, Y; Jayamohan, S; Johnson, JD; Lai, Z; Li, W; Lv, Y; Palacios, BE; Pratap, UP; Sareddy, GR; Suzuki, T; Tekmal, RR; Vadlamudi, RK; Venkata, PP; Viswanadhapalli, S; Weldon, K; Ye, Z; Zhao, W; Zheng, S; Zou, Y	1
Aldape, K; Bhaduri, A; Chinnaiyan, AM; Cieslik, M; Englinger, B; Filbin, MG; Jiang, L; Joshi, PK; Nano, PR; Pfister, S; Pratt, D; Pun, M; Rao, A; Venneti, S	1
Cai, J; Chen, C; Chen, J; Chen, Z; Fan, Z; Gu, J; Guo, C; Hu, J; Jiang, B; Leng, T; Li, Q; Liang, J; Liang, X; Lin, Y; Liu, X; Mai, J; Sai, K; Sun, S; Wang, J; Xu, J; Yan, G; Yang, W; Yin, W; Zhong, Y; Zhu, W	1
Cong, H; Dong, C; Fan, B; Guo, X; Liu, Y; Sui, A	1
Cao, X; Chinnaiyan, AM; Chung, C; Ding, Y; Hawes, D; Judkins, AR; Mota, M; Natarajan, SK; Parolia, A; Pun, M; Samajdar, S; Sweha, SR; Venneti, S; Xiao, L; Yang, F	1
Fu, X; Li, J; Li, T; Shang, W; Wang, J; Wang, X; Zhang, L	1
Andrade, J; Garcia, BA; Granat, J; Jin, Y; Lee, CH; LeRoy, G; Lund, P; Reinberg, D; Saldaña-Meyer, R; Stafford, JM; Ueberheide, B; Yu, JR	1
Arzt, M; Filbin, MG; Gillespie, SM; Hovestadt, V; Kambhampati, M; Lennon, JJ; Monje, M; Nagaraja, S; Nazarian, J; Quezada, MA; Suva, ML; Woo, PJ	1
Bailey, CP; Becher, OJ; Chandra, J; Collier, T; Figueroa, M; Gangadharan, A; Gopalakrishnan, V; Henry, V; Kennis, BA; Lee, DA; Monje, M; Nazarian, J; Romero, MM; Wang, L; Yadavilli, S; Yang, Y; Zaky, W	1
Bao, S; Chen, L; Cui, J; Guo, S; Han, Q; He, K; Huang, H; Li, A; Li, D; Li, T; Li, Y; Man, J; Mi, L; Ran, H; Rich, JN; Wang, X; Wu, J; Xiao, D; Yan, X; Yu, Y; Zhan, X; Zhang, S; Zhang, X; Zhou, T	1
Amer, N; El-Ayadi, M; El-Beltagy, M; El-Naggar, S; Hassan, Z; Khorshed, EN; Mosaab, A; Refaat, A; Soror, SH; Zaghloul, MS	1
Bush, K; Carcaboso, AM; Cervantes, V; Chen, KY; Klein, RH; Knoepfler, PS; Lechpammer, M; Lewis, N; Naqvi, A	1
Hashizume, R; Nicolaides, TP	1
Allis, CD; Deshmukh, S; Garcia, BA; Jabado, N; Jain, SU; Juretic, N; Khazaei, S; Lewis, PW; Lu, C; Lundgren, SM; Marchione, DM; Wang, X; Weinberg, DN	1
Alimova, I; Balakrishnan, I; Birks, DK; Carcaboso, AM; Dahl, N; Danis, E; Davidson, N; Donson, A; Foreman, N; Fosmire, S; Gilani, A; Green, A; Gupta, N; Hashizume, R; Hawkins, C; Hulleman, E; Jabado, N; Jones, K; Katagi, H; Lemma, R; Madhavan, K; Meel, MH; Metselaar, DS; Monje, M; Pierce, A; Sanford, B; Serkova, NJ; Sola, I; Steiner, J; Venkataraman, S; Vibhakar, R; Vijmasi, T; Wang, D	1
Chen, L; Qiu, Q; Yang, J	1
Bareke, E; Chen, H; Coradin, M; Garcia, BA; Harutyunyan, AS; Horth, C; Jabado, N; Krug, B; Lu, T; Majewski, J; Marchione, DM; Nikbakht, H; Russo, C	1
A, D; Albrecht, S; Andrade, AF; Bajic, A; Bandopadhayay, P; Bassenden, AV; Berghuis, AM; Beroukhim, R; Blanchette, M; Bognar, L; Brandner, S; Chen, CCL; Coutelier, M; Dali, R; De Jay, N; Deshmukh, S; Dubois, F; Ekert, PG; Ellezam, B; Faury, D; Filbin, MG; Garcia, BA; Garzia, L; Gayden, T; Hadjadj, D; Hansford, JR; Harutyunyan, AS; Hauser, P; Hébert, S; Jabado, N; Jawhar, W; Jessa, S; Jones, DTW; Juretic, N; Karamchandani, J; Khuong-Quang, DA; Kleinman, CL; Klekner, A; Korshunov, A; Kramm, C; Krskova, L; Ligon, KL; Lisi, V; Mack, SC; Maestro, N; Marchione, DM; Mikael, LG; Pathania, M; Pfister, SM; Russo, C; Salomoni, P; Sturm, D; Sumerauer, D; Suzuki, H; Taylor, MD; Vanova, K; Vicha, A; Virga, J; Weil, AG; Woodward, E; Zamecnik, J; Zapotocky, M; Zeinieh, M; Ziegler, DS	1
Agnihotri, S; Bridge, T; Hawkins, C; Huang, A; Kim, B; Li, C; Milos, S; Pajovic, S; Patel, P; Phillips, L; Rakopoulos, P; Ryall, S; Sheth, J; Siddaway, R; Srikanthan, D; Yu, M	1
Alfazema, N; Bracken, AP; Bressan, RB; Brien, GL; Deevy, O; Doherty, AM; Fitzpatrick, DJ; Gannon, D; Grant, V; Healy, E; Lagan, E; Marqués-Torrejón, MA; Monger, C; Neikes, H; Pollard, SM	1
Anderson, J; Cantilena, S; de Boer, J; Hargrave, D; Meier, S; Michod, D; Niklison Chirou, MV; Salomoni, P	1
Cui, J; Han, J; Ou, J; Qin, Y; Wang, RF; Zhang, C; Zhang, J; Zhi, F	1
Ferrigno, C; Holdhoff, M; Javadi, MS; Laterra, JJ; Menke, JR; Pomper, MG; Rowe, SP; Salas Fragomeni, RA; Solnes, LB; Szabo, Z	1
Chen, Q; Guo, Q; He, X; Jiang, C; Jiang, X; Liu, L; Liu, Y; Lu, Y; Ruan, C; Sun, T; Wang, Q; Zhang, Y	1
Haldar, D; Vadla, R	1
Dai, B; Guan, F; Hu, Z; Huang, H; Mao, B; Su, H; Xiao, Z; Zhu, G	1
Cai, J; Dinislam, M; Duan, C; Gao, F; Gao, W; Han, B; Jiang, C; Kang, C; Lin, L; Meng, X; Wang, R; Wu, P	1
Cai, C; Daoud, EV; Foong, C; Hatanpaa, KJ; Martin, GR; Mickey, BE; Oberle, RJ; Pan, E; Raisanen, JM; Rajaram, V; White, CL	1
Arnold, EP; Haile, S; Hulleman, E; Kadapakkam, M; Labanieh, L; Mackall, CL; Majzner, RG; Monje, M; Mount, CW; Rietberg, SP; Sundaresh, S; Vogel, H; Woo, PJ	1
Budka, H; Leske, H; Niehusmann, P; Pahnke, J; Panagopoulos, I; Rushing, E	1
Bannykh, S; Bastian, BC; Bollen, AW; Cham, E; Cooney, T; Danielpour, M; Fan, X; Grenert, JP; Hu, J; Johnston, J; Jones, DTW; Kool, M; Korshunov, A; Li, R; McDermott, M; Oberheim Bush, NA; Onodera, C; Pekmezci, M; Perry, A; Pfister, SM; Sill, M; Solomon, DA; Sun, PP; Van Ziffle, J; Villanueva-Meyer, JE	1
Anderson, B; Bruzek, A; Carcaboso, AM; Garcia, T; Garton, H; Hashizume, R; Heth, J; Koschmann, C; McMurray, KQ; Miklja, Z; Mody, R; Mullan, B; Muraszko, K; Robertson, PL; Savelieff, MG; Siada, R; Singer, BH; Stallard, S; Venneti, S; Wierzbicki, K	1
Gorin, MA; Pienta, KJ; Pomper, MG; Rowe, SP; Salas Fragomeni, RA	1
Barret, E; Castel, D; Debily, MA; Grill, J; Jones, C; Jones, DTW; Kergrohen, T; Kramm, CM; Merlevede, J; Pfister, SM; Philippe, C; Puget, S; Sainte-Rose, C; Sill, M; Varlet, P	1
Bayin, NS; Chapman, JR; Descostes, N; Karajannis, MA; Lee, CH; Leroy, G; Modrek, AS; Oksuz, O; Placantonakis, DG; Reinberg, D; Saldaña-Meyer, R; Snuderl, M; Stafford, JM; Suarez, F; Ueberheide, B; Voigt, P; Yu, JR	1
Sang, B; Wang, F; Wei, Y; Xu, Z; Yang, D	1
Byun, HS; Choi, SW; Hong, JH; Huang, SM; Hur, GM; Jeon, J; Kim, JM; Kim, SH; Lee, JH; Lee, Y; Li, Y; Liu, ZG; Lu, T; Park, J; Park, KA; Ro, H; Shen, HM; Sohn, KC; Stark, GR; Zhang, T	1
Allis, CD; Lewis, PW	1
Feng, D; Hu, Q; Li, H; Ma, H; Su, Y; Tao, H; Wang, X; Zhang, C	1
Butterfield, LH; Connelly, AK; Dibridge, SA; Hamilton, RL; Jakacki, RI; Okada, H; Panigrahy, A; Pollack, IF; Potter, DM; Whiteside, TL	1
Eissenberg, JC; Florens, L; Gao, X; Herz, HM; Jackson, J; Morgan, M; Rickels, R; Shilatifard, A; Swanson, SK; Washburn, MP	1
Daniels, D; Han, J; Huang, H; Zhang, R; Zhang, Z	1
Gao, JL; Hu, G; Lin, YJ; Liu, J; Tian, YX; Wei, J; Zhang, K; Zhen, YZ	1
Cui, J; Ou, J; Xia, X; Yang, Z; Zhang, J; Zhi, F	1
Karst, A; Lehnus, M; Pehar, M; Puglielli, L	1
Barth, RF; Ciesielski, MJ; Fenstermaker, RA; Kazim, AL	1
Bulte, JW; Gilad, AA; McMahon, MT; Raman, V; Skoglund, CM; van Laarhoven, HW; van Zijl, PC; Walczak, P; Winnard, PT	1
Badn, W; Darabi, A; Esbjörnsson, M; Fellert, MA; Hegardt, P; Janelidze, S; Salford, LG; Siesjö, P; Smith, KE; Visse, E	1
Badn, W; Darabi, A; Salford, LG; Siesjö, P; Smith, KE; Visse, E	1
Ivanov, V; Kalinovsky, T; Niedzwiecki, A; Rath, M; Roomi, MW	1
Busek, P; Krepela, E; Sedo, A; Stremeňová, J	1
Beckman, EJ; Petoud, S; Pollack, IF; Sivak, WN; Zamboni, WC; Zhang, J	1
Autry, SA; Boggan, JE; Higgins, RJ; Leach, MW; Lee, SJ; Smith, KM	1
Felsenstein, KM; Ingalls, KM; Ripellino, JA; Robakis, NK; Roberts, SB	1
Debinski, W; Gibo, DM; Kealiher, A; Obiri, NI; Puri, RK	1
Berens, ME; Djawaheri, J; Giese, A; Hagel, C; Kim, EL; Westphal, M; Zapf, S	1
Autry, S; Boggan, JE; Higgins, RJ; Leach, MW; Lee, SJ; Smith, KM	1
Hannuniemi, R; Oja, OS; Oja, SS; Pajari-Backas, M	1

Reviews

3 review(s) available for lysine and Glial Cell Tumors

Article	Year
Role of Lysine-specific Demethylase 1 and Its Small Molecule Inhibitors in Glioblastoma Multiforme Therapy. Anti-cancer agents in medicinal chemistry, 2022, Volume: 22, Issue:18 Topics: Flavins; Glioblastoma; Glioma; Histone Demethylases; Histones; Humans; Lysine; Neoplasm Recurrence, Local	2022
Histone H3 K27 alterations in central nervous system tumours: Challenges and alternative diagnostic approaches. Molecular and cellular probes, 2022, Volume: 66 Topics: Central Nervous System Neoplasms; Child; Glioma; Histones; Humans; Lysine; Methionine	2022
Histone Lysine-to-Methionine Mutation as Anticancer Drug Target. Advances in experimental medicine and biology, 2021, Volume: 1283 Topics: Antineoplastic Agents; Chondroblastoma; Glioma; Histones; Humans; Lysine; Methionine; Mutation	2021

Trials

1 trial(s) available for lysine and Glial Cell Tumors

Article	Year
Antigen-specific immune responses and clinical outcome after vaccination with glioma-associated antigen peptides and polyinosinic-polycytidylic acid stabilized by lysine and carboxymethylcellulose in children with newly diagnosed malignant brainstem and n Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2014, Jul-01, Volume: 32, Issue:19 Topics: Adolescent; Antigens, Neoplasm; Brain Neoplasms; Brain Stem Neoplasms; Cancer Vaccines; Carboxymethylcellulose Sodium; Child; Child, Preschool; Disease-Free Survival; Drug Carriers; Enzyme-Linked Immunospot Assay; Epitopes; Female; Glioma; Humans; Immunohistochemistry; Immunotherapy, Active; Infant; Inhibitor of Apoptosis Proteins; Injections, Subcutaneous; Interferon Inducers; Interleukin-13 Receptor alpha1 Subunit; Kaplan-Meier Estimate; Lysine; Magnetic Resonance Imaging; Male; Poly I-C; Receptor, EphA2; Receptors, Interleukin-13; Survivin; Young Adult	2014

Article

Year

Antigen-specific immune responses and clinical outcome after vaccination with glioma-associated antigen peptides and polyinosinic-polycytidylic acid stabilized by lysine and carboxymethylcellulose in children with newly diagnosed malignant brainstem and n

Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2014, Jul-01, Volume: 32, Issue:19

Topics: Adolescent; Antigens, Neoplasm; Brain Neoplasms; Brain Stem Neoplasms; Cancer Vaccines; Carboxymethylcellulose Sodium; Child; Child, Preschool; Disease-Free Survival; Drug Carriers; Enzyme-Linked Immunospot Assay; Epitopes; Female; Glioma; Humans; Immunohistochemistry; Immunotherapy, Active; Infant; Inhibitor of Apoptosis Proteins; Injections, Subcutaneous; Interferon Inducers; Interleukin-13 Receptor alpha1 Subunit; Kaplan-Meier Estimate; Lysine; Magnetic Resonance Imaging; Male; Poly I-C; Receptor, EphA2; Receptors, Interleukin-13; Survivin; Young Adult

2014

Other Studies

57 other study(ies) available for lysine and Glial Cell Tumors

Article	Year
Dual role of pseudogene TMEM198B in promoting lipid metabolism and immune escape of glioma cells. Oncogene, 2022, Volume: 41, Issue:40 Topics: ATP Citrate (pro-S)-Lyase; DNA-Binding Proteins; Fatty Acid Elongases; Fatty Acids; Glioma; Histones; Humans; Lipid Metabolism; Lipids; Lysine; Pseudogenes; RNA-Binding Proteins; Transcription Factors; Tumor Microenvironment	2022
Lysine-specific histone demethylase 1A (KDM1A/LSD1) inhibition attenuates DNA double-strand break repair and augments the efficacy of temozolomide in glioblastoma. Neuro-oncology, 2023, Jul-06, Volume: 25, Issue:7 Topics: Animals; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; DNA; DNA Breaks, Double-Stranded; DNA Repair; Drug Resistance, Neoplasm; Glioblastoma; Glioma; Histone Demethylases; Lysine; Mice; Tandem Mass Spectrometry; Temozolomide; Xenograft Model Antitumor Assays	2023
Common molecular features of H3K27M DMGs and PFA ependymomas map to hindbrain developmental pathways. Acta neuropathologica communications, 2023, 02-09, Volume: 11, Issue:1 Topics: Brain Neoplasms; Ependymoma; Fluorocarbons; Glioma; Histones; Humans; Lysine; Mutation; Rhombencephalon	2023
Differential regulation of H3K9/H3K14 acetylation by small molecules drives neuron-fate-induction of glioma cell. Cell death & disease, 2023, 02-20, Volume: 14, Issue:2 Topics: Acetylation; Glioblastoma; Glioma; Histone Deacetylase Inhibitors; Histones; Humans; Lysine	2023
Dimethylation of histone H3 lysine 36 (H3K36me2) as a potential biomarker for glioma diagnosis, grading, and prognosis. Journal of neuropathology and experimental neurology, 2023, 04-20, Volume: 82, Issue:5 Topics: Biomarkers; Brain Neoplasms; DNA Methylation; Glioma; Histones; Humans; Isocitrate Dehydrogenase; Lysine; Middle Aged; Mutation; Neoplasm Grading; Prognosis	2023
Targeting SWI/SNF ATPases in H3.3K27M diffuse intrinsic pontine gliomas. Proceedings of the National Academy of Sciences of the United States of America, 2023, 05-02, Volume: 120, Issue:18 Topics: Adenosine Triphosphatases; Brain Neoplasms; Child; Chromatin; Diffuse Intrinsic Pontine Glioma; DNA Helicases; Glioma; Histones; Humans; Lysine; Mutation; Nuclear Proteins; Transcription Factors	2023
Mechanism of NURP1 in temozolomide resistance in hypoxia-treated glioma cells via the KDM3A/TFEB axis. Oncology research, 2023, Volume: 31, Issue:3 Topics: Animals; Autophagy; Basic Helix-Loop-Helix Leucine Zipper Transcription Factors; Disease Models, Animal; Glioma; Humans; Hypoxia; Jumonji Domain-Containing Histone Demethylases; Lysine; Nuclear Proteins; Temozolomide	2023
Automethylation of PRC2 promotes H3K27 methylation and is impaired in H3K27M pediatric glioma. Genes & development, 2019, 10-01, Volume: 33, Issue:19-20 Topics: Child; Enzyme Activation; Gene Silencing; Glioma; Histones; Humans; Lysine; Methylation; Polycomb Repressive Complex 2; Protein Subunits	2019
Histone Variant and Cell Context Determine H3K27M Reprogramming of the Enhancer Landscape and Oncogenic State. Molecular cell, 2019, 12-19, Volume: 76, Issue:6 Topics: Brain; Brain Neoplasms; Cellular Reprogramming; Diffuse Intrinsic Pontine Glioma; Enhancer Elements, Genetic; Epigenesis, Genetic; Epigenomics; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Glioma; Histones; Humans; Lysine; Mutation; Pons; Signal Transduction; Transcriptome	2019
Pharmacologic inhibition of lysine-specific demethylase 1 as a therapeutic and immune-sensitization strategy in pediatric high-grade glioma. Neuro-oncology, 2020, 09-29, Volume: 22, Issue:9 Topics: Animals; Brain Stem Neoplasms; Child; Glioma; Histones; Humans; Lysine; Mice; Mutation	2020
Glioma stem-like cells evade interferon suppression through MBD3/NuRD complex-mediated STAT1 downregulation. The Journal of experimental medicine, 2020, 05-04, Volume: 217, Issue:5 Topics: Acetylation; Aged; Carcinogenesis; Cell Line, Tumor; Cell Proliferation; Cyclin-Dependent Kinase Inhibitor p21; Disease Progression; DNA-Binding Proteins; Down-Regulation; Female; Gene Expression Regulation, Neoplastic; Glioma; Histones; Humans; Interferons; Lysine; Male; Mi-2 Nucleosome Remodeling and Deacetylase Complex; Middle Aged; Neoplastic Stem Cells; Promoter Regions, Genetic; STAT1 Transcription Factor; Up-Regulation	2020
Histone H3K27M Mutation Overrides Histological Grading in Pediatric Gliomas. Scientific reports, 2020, 05-20, Volume: 10, Issue:1 Topics: Brain; Brain Neoplasms; Child; Child, Preschool; Clinical Decision-Making; Disease-Free Survival; DNA Mutational Analysis; Egypt; Female; Follow-Up Studies; Genetic Testing; Glioma; Histones; Humans; Kaplan-Meier Estimate; Lysine; Male; Medical Oncology; Mutation; Neoplasm Grading; Practice Guidelines as Topic; Prognosis; Risk Assessment	2020
Reciprocal H3.3 gene editing identifies K27M and G34R mechanisms in pediatric glioma including NOTCH signaling. Communications biology, 2020, 07-09, Volume: 3, Issue:1 Topics: Animals; Apoptosis; Biomarkers, Tumor; Brain Neoplasms; Cell Proliferation; Child; Female; Gene Editing; Gene Expression Regulation, Neoplastic; Glioma; Glycine; Histones; Humans; Lysine; Male; Mice; Mice, Inbred NOD; Mice, SCID; Mutation; Receptors, Notch; Tumor Cells, Cultured; Xenograft Model Antitumor Assays	2020
LSD1 inhibition in pHGG: the key to unleashing immunotherapy? Neuro-oncology, 2020, 09-29, Volume: 22, Issue:9 Topics: Child; Glioma; Histone Demethylases; Humans; Immunotherapy; Lysine	2020
Histone H3.3 G34 mutations promote aberrant PRC2 activity and drive tumor progression. Proceedings of the National Academy of Sciences of the United States of America, 2020, 11-03, Volume: 117, Issue:44 Topics: Chromatin; Gene Expression; Gene Expression Regulation; Glioma; HEK293 Cells; Histone-Lysine N-Methyltransferase; Histones; Humans; Lysine; Mesenchymal Stem Cells; Methylation; Mutation; Neoplastic Processes; Polycomb Repressive Complex 1; Polycomb Repressive Complex 2; Protein Processing, Post-Translational	2020
Senescence Induced by BMI1 Inhibition Is a Therapeutic Vulnerability in H3K27M-Mutant DIPG. Cell reports, 2020, 10-20, Volume: 33, Issue:3 Topics: Aging; Astrocytoma; Brain Stem Neoplasms; Cell Differentiation; Cell Line, Tumor; Cell Proliferation; Child; Child, Preschool; Chromatin; Diffuse Intrinsic Pontine Glioma; Epigenomics; Female; Glioma; Histones; Humans; Lysine; Male; Mutation; Neoplasm Recurrence, Local; Polycomb Repressive Complex 1	2020
H3K27M in Gliomas Causes a One-Step Decrease in H3K27 Methylation and Reduced Spreading within the Constraints of H3K36 Methylation. Cell reports, 2020, 11-17, Volume: 33, Issue:7 Topics: Cell Line, Tumor; Chromatin; DNA Methylation; Epigenomics; Gene Expression; Gene Expression Regulation, Neoplastic; Glioma; Histones; Humans; Lysine; Methionine; Methylation; Mutation; Polycomb Repressive Complex 2; Protein Processing, Post-Translational	2020
Histone H3.3G34-Mutant Interneuron Progenitors Co-opt PDGFRA for Gliomagenesis. Cell, 2020, 12-10, Volume: 183, Issue:6 Topics: Animals; Astrocytes; Brain Neoplasms; Carcinogenesis; Cell Lineage; Cellular Reprogramming; Chromatin; Embryo, Mammalian; Epigenesis, Genetic; Gene Expression Regulation, Neoplastic; Gene Silencing; Glioma; Histones; Interneurons; Lysine; Mice, Inbred C57BL; Models, Biological; Mutation; Neoplasm Grading; Neural Stem Cells; Oligodendroglia; Promoter Regions, Genetic; Prosencephalon; Receptor, Platelet-Derived Growth Factor alpha; Transcription, Genetic; Transcriptome	2020
Epigenetic activation of a RAS/MYC axis in H3.3K27M-driven cancer. Nature communications, 2020, 12-04, Volume: 11, Issue:1 Topics: Animals; Brain Neoplasms; Disease Models, Animal; Epigenesis, Genetic; Epigenomics; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Glioma; Histones; Humans; Lysine; Methylation; Mice, Knockout; Proto-Oncogene Proteins c-myc; ras Proteins; Tumor Suppressor Protein p53	2020
Simultaneous disruption of PRC2 and enhancer function underlies histone H3.3-K27M oncogenic activity in human hindbrain neural stem cells. Nature genetics, 2021, Volume: 53, Issue:8 Topics: Animals; Brain Neoplasms; Cell Differentiation; Cell Line; Enhancer Elements, Genetic; Enhancer of Zeste Homolog 2 Protein; Epigenome; Gene Expression Regulation, Developmental; Glioma; Histones; Humans; Lysine; Male; Mice, Inbred Strains; Mutation; Neural Stem Cells; Oncogenes; Polycomb Repressive Complex 2; Promoter Regions, Genetic; Rhombencephalon	2021
Alcohol-abuse drug disulfiram targets pediatric glioma via MLL degradation. Cell death & disease, 2021, 08-11, Volume: 12, Issue:8 Topics: Alcoholism; Auranofin; Cell Line, Tumor; Cell Proliferation; Child; Disulfiram; Down-Regulation; Drug Repositioning; Drug Synergism; Gene Expression Regulation, Neoplastic; Glioma; Histone-Lysine N-Methyltransferase; Histones; Humans; Lysine; Methylation; Myeloid-Lymphoid Leukemia Protein; Neoplasm Grading; Protein Processing, Post-Translational; Proteolysis; Transcription, Genetic	2021
TRIM45 functions as a tumor suppressor in the brain via its E3 ligase activity by stabilizing p53 through K63-linked ubiquitination. Cell death & disease, 2017, 05-25, Volume: 8, Issue:5 Topics: Animals; Apoptosis; Biocatalysis; Brain; Brain Neoplasms; Cell Line, Tumor; Cell Proliferation; Disease Progression; Down-Regulation; Gene Expression Regulation, Neoplastic; Glioma; Humans; Lysine; Mice, Inbred BALB C; Mice, Nude; Models, Biological; Protein Stability; Repressor Proteins; RNA, Messenger; Signal Transduction; Tumor Suppressor Protein p53; Ubiquitin-Protein Ligases; Ubiquitination	2017
Prostate-Specific Membrane Antigen-Targeted Imaging With [18F]DCFPyL in High-Grade Gliomas. Clinical nuclear medicine, 2017, Volume: 42, Issue:10 Topics: Antigens, Surface; Brain Neoplasms; Glioma; Glutamate Carboxypeptidase II; Humans; Lysine; Magnetic Resonance Imaging; Male; Neoplasm Grading; Positron-Emission Tomography; Urea	2017
Substance P Mediated DGLs Complexing with DACHPt for Targeting Therapy of Glioma. ACS applied materials & interfaces, 2017, Oct-11, Volume: 9, Issue:40 Topics: Blood-Brain Barrier; Brain Neoplasms; Cell Line, Tumor; Drug Delivery Systems; Glioma; Humans; Lysine; Substance P	2017
Mammalian target of rapamycin complex 2 (mTORC2) controls glycolytic gene expression by regulating Histone H3 Lysine 56 acetylation. Cell cycle (Georgetown, Tex.), 2018, Volume: 17, Issue:1 Topics: Acetylation; Cell Line, Tumor; Gene Expression Regulation, Neoplastic; Glioma; Glycolysis; HeLa Cells; Histones; Humans; Lysine; Mechanistic Target of Rapamycin Complex 2; Models, Biological; Promoter Regions, Genetic; Signal Transduction; Sirtuins	2018
Histone demethylase KDM5A inhibits glioma cells migration and invasion by down regulating ZEB1. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2018, Volume: 99 Topics: Biocatalysis; Biomarkers, Tumor; Cell Line, Tumor; Cell Movement; Down-Regulation; Epithelial-Mesenchymal Transition; Gene Expression Regulation, Neoplastic; Gene Knockdown Techniques; Glioma; Histones; Humans; Lysine; Methylation; Neoplasm Invasiveness; Neoplasm Metastasis; Promoter Regions, Genetic; Retinoblastoma-Binding Protein 2; Zinc Finger E-box-Binding Homeobox 1	2018
Loss of ATRX suppresses ATM dependent DNA damage repair by modulating H3K9me3 to enhance temozolomide sensitivity in glioma. Cancer letters, 2018, 04-10, Volume: 419 Topics: Animals; Antineoplastic Agents, Alkylating; Ataxia Telangiectasia Mutated Proteins; Brain Neoplasms; Cell Line, Tumor; Cell Survival; DNA Damage; DNA Repair; Female; Gene Expression Regulation, Neoplastic; Gene Knockout Techniques; Glioma; Histones; Humans; Lysine; Methylation; Mice, Nude; Temozolomide; X-linked Nuclear Protein; Xenograft Model Antitumor Assays	2018
Adult Brainstem Gliomas With H3K27M Mutation: Radiology, Pathology, and Prognosis. Journal of neuropathology and experimental neurology, 2018, 04-01, Volume: 77, Issue:4 Topics: Adult; Antigens, CD; Antigens, Differentiation, Myelomonocytic; Brain Stem Neoplasms; Female; Follow-Up Studies; Glioma; Histones; Humans; Ki-67 Antigen; Lysine; Magnetic Resonance Imaging; Male; Methionine; Middle Aged; Mutation; Neurofilament Proteins; Retrospective Studies	2018
Potent antitumor efficacy of anti-GD2 CAR T cells in H3-K27M Nature medicine, 2018, Volume: 24, Issue:5 Topics: Animals; Brain Neoplasms; Gangliosides; Glioma; Histones; Humans; Immunotherapy, Adoptive; Lysine; Methylation; Mice; Receptors, Antigen, T-Cell; Xenograft Model Antitumor Assays	2018
K27/G34 versus K28/G35 in histone H3-mutant gliomas: A note of caution. Acta neuropathologica, 2018, Volume: 136, Issue:1 Topics: Brain Neoplasms; DNA Mutational Analysis; Glioma; Glycine; Histones; Humans; Lysine; Mutation	2018
Myxoid glioneuronal tumor of the septum pellucidum and lateral ventricle is defined by a recurrent PDGFRA p.K385 mutation and DNT-like methylation profile. Acta neuropathologica, 2018, Volume: 136, Issue:2 Topics: Adult; Child; DNA Methylation; DNA Modification Methylases; DNA Repair Enzymes; Female; Glioma; Humans; Lateral Ventricles; Lysine; Magnetic Resonance Imaging; Male; Mutation; Neoplasms, Neuroepithelial; Receptor, Platelet-Derived Growth Factor alpha; Septum Pellucidum; Tumor Suppressor Proteins; Young Adult	2018
CSF H3F3A K27M circulating tumor DNA copy number quantifies tumor growth and in vitro treatment response. Acta neuropathologica communications, 2018, 08-15, Volume: 6, Issue:1 Topics: Adolescent; Brain Neoplasms; Cell Proliferation; Child; Circulating Tumor DNA; DNA Copy Number Variations; Female; Glioma; Histones; Humans; In Vitro Techniques; Lysine; Magnetic Resonance Imaging; Male; Methionine; Mutation	2018
Uptake of Prostate-Specific Membrane Antigen-Targeted 18F-DCFPyL in Cerebral Radionecrosis: Implications for Diagnostic Imaging of High-Grade Gliomas. Clinical nuclear medicine, 2018, Volume: 43, Issue:11 Topics: Aged; Antigens, Surface; Biological Transport; Brain; Glioma; Glutamate Carboxypeptidase II; Humans; Lysine; Male; Necrosis; Neoplasm Grading; Positron-Emission Tomography; Urea	2018
Transcriptomic and epigenetic profiling of 'diffuse midline gliomas, H3 K27M-mutant' discriminate two subgroups based on the type of histone H3 mutated and not supratentorial or infratentorial location. Acta neuropathologica communications, 2018, 11-05, Volume: 6, Issue:1 Topics: Adolescent; Brain; Brain Neoplasms; Child; Child, Preschool; DNA Methylation; Epigenomics; Female; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Glioma; Histones; Humans; Lysine; Male; Methionine; Mutation; Principal Component Analysis; Transcriptome; Tumor Cells, Cultured	2018
Multiple modes of PRC2 inhibition elicit global chromatin alterations in H3K27M pediatric glioma. Science advances, 2018, Volume: 4, Issue:10 Topics: Animals; Brain Stem Neoplasms; Cells, Cultured; Child; Chromatin; Disease Models, Animal; Embryonic Stem Cells; Glioma; Histones; Humans; Lysine; Mice; Polycomb Repressive Complex 2	2018
Activation of KRas-ERK1/2 signaling drives the initiation and progression of glioma by suppressing the acetylation of histone H4 at lysine 16. Life sciences, 2019, May-15, Volume: 225 Topics: Acetylation; Apoptosis; Cell Movement; Cell Proliferation; Glioma; Histones; Humans; Lysine; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Protein Processing, Post-Translational; Proto-Oncogene Proteins p21(ras); Signal Transduction; Tumor Cells, Cultured	2019
PHF20 regulates NF-κB signalling by disrupting recruitment of PP2A to p65. Nature communications, 2013, Volume: 4 Topics: Antigens, Neoplasm; Biomarkers, Tumor; Brain Neoplasms; DNA-Binding Proteins; Glioma; HEK293 Cells; HeLa Cells; Humans; Immunohistochemistry; Lysine; Methylation; Models, Biological; Phosphorylation; Protein Binding; Protein Phosphatase 2; Signal Transduction; Transcription Factor RelA; Transcription Factors; Tumor Necrosis Factor-alpha	2013
Poisoning the "histone code" in pediatric gliomagenesis. Cell cycle (Georgetown, Tex.), 2013, Oct-15, Volume: 12, Issue:20 Topics: Brain Neoplasms; Child; Exome; Glioma; Histone Code; Histones; Humans; Lysine; Models, Biological; Mutation; Polycomb Repressive Complex 2	2013
Histone methyltransferase G9a and H3K9 dimethylation inhibit the self-renewal of glioma cancer stem cells. Molecular and cellular biochemistry, 2014, Volume: 394, Issue:1-2 Topics: AC133 Antigen; Antigens, CD; Azepines; Brain Neoplasms; Cell Line, Tumor; Cell Proliferation; Enzyme Inhibitors; Gene Expression Regulation, Neoplastic; Glioma; Glycoproteins; Histocompatibility Antigens; Histone-Lysine N-Methyltransferase; Histones; Humans; Lysine; Methylation; Neoplastic Stem Cells; Peptides; Promoter Regions, Genetic; Quinazolines; Signal Transduction; SOXB1 Transcription Factors; Transfection	2014
Histone H3 lysine-to-methionine mutants as a paradigm to study chromatin signaling. Science (New York, N.Y.), 2014, Aug-29, Volume: 345, Issue:6200 Topics: Amino Acid Substitution; Animals; Chromatin; Disease Models, Animal; Drosophila melanogaster; Drosophila Proteins; Gene Silencing; Glioma; Heterochromatin; Histone-Lysine N-Methyltransferase; Histones; Jumonji Domain-Containing Histone Demethylases; Lysine; Methionine; Methylation; Mutation; Signal Transduction	2014
Detecting the H3F3A mutant allele found in high-grade pediatric glioma by real-time PCR. Journal of neuro-oncology, 2016, Volume: 126, Issue:1 Topics: Animals; Brain Neoplasms; Child; DNA Mutational Analysis; Gene Library; Glioma; Histones; Humans; Lysine; Male; Methionine; Mice; Mutation; Real-Time Polymerase Chain Reaction; Tumor Cells, Cultured; Xenograft Model Antitumor Assays	2016
Antitumor activity of rhein lysinate against human glioma U87 cells in vitro and in vivo. Oncology reports, 2016, Volume: 35, Issue:3 Topics: Animals; Anthraquinones; Antineoplastic Agents, Phytogenic; Apoptosis; Apoptosis Regulatory Proteins; bcl-2-Associated X Protein; Bcl-2-Like Protein 11; Cell Line, Tumor; Cell Proliferation; Cyclin D; Gene Expression Regulation, Neoplastic; Glioma; Humans; Lysine; Membrane Proteins; Mice; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-2; Reactive Oxygen Species; Xenograft Model Antitumor Assays	2016
The F-box protein FBXL18 promotes glioma progression by promoting K63-linked ubiquitination of Akt. FEBS letters, 2017, Volume: 591, Issue:1 Topics: Apoptosis; Bcl-2-Like Protein 11; Brain Neoplasms; Cell Line, Tumor; Cell Proliferation; Disease Progression; F-Box Proteins; Gene Expression Regulation, Neoplastic; Gene Knockdown Techniques; Glioma; Humans; Lysine; Phosphatidylinositol 3-Kinases; Phosphorylation; Proto-Oncogene Proteins c-akt; RNA, Messenger; Signal Transduction; Ubiquitination; Up-Regulation	2017
Proteomic assessment shows that many endoplasmic reticulum (ER)-resident proteins are targeted by N(epsilon)-lysine acetylation in the lumen of the organelle and predicts broad biological impact. The Journal of biological chemistry, 2012, Jun-29, Volume: 287, Issue:27 Topics: Acetyl Coenzyme A; Acetylation; Brain Neoplasms; Calreticulin; Cell Line, Tumor; Endoplasmic Reticulum; Endoplasmic Reticulum Chaperone BiP; Glioma; Heat-Shock Proteins; Humans; Lysine; Membrane Proteins; Plasmids; Protein Folding; Protein Processing, Post-Translational; Proteomics	2012
Cellular antitumor immune response to a branched lysine multiple antigenic peptide containing epitopes of a common tumor-specific antigen in a rat glioma model. Cancer immunology, immunotherapy : CII, 2005, Volume: 54, Issue:2 Topics: Animals; Antibodies, Monoclonal; Antigens, Neoplasm; Brain Neoplasms; Cancer Vaccines; Epitopes; ErbB Receptors; Glioma; Granulocyte-Macrophage Colony-Stimulating Factor; Humans; Immunity, Cellular; Immunotherapy; Interleukin-4; Lysine; Male; Models, Animal; Peptide Fragments; Rats; Rats, Inbred F344; Spleen; Survival Rate; T-Lymphocytes; T-Lymphocytes, Cytotoxic; Th2 Cells; Vaccination	2005
Artificial reporter gene providing MRI contrast based on proton exchange. Nature biotechnology, 2007, Volume: 25, Issue:2 Topics: Animals; Brain Neoplasms; Cell Line, Tumor; Contrast Media; Genes, Reporter; Glioma; Image Enhancement; Lysine; Magnetic Resonance Imaging; Mice; Protons; Recombinant Proteins	2007
Inhibition of inducible nitric oxide synthase enhances anti-tumour immune responses in rats immunized with IFN-gamma-secreting glioma cells. Scandinavian journal of immunology, 2007, Volume: 65, Issue:3 Topics: Animals; B-Lymphocytes; Brain Neoplasms; CD4-Positive T-Lymphocytes; CD8-Positive T-Lymphocytes; Cell Proliferation; Enzyme Inhibitors; Flow Cytometry; Glioma; Immunotherapy; Interferon-gamma; Lysine; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase Type II; Rats; Rats, Inbred F344	2007
Postimmunization with IFN-gamma-secreting glioma cells combined with the inducible nitric oxide synthase inhibitor mercaptoethylguanidine prolongs survival of rats with intracerebral tumors. Journal of immunology (Baltimore, Md. : 1950), 2007, Sep-15, Volume: 179, Issue:6 Topics: Animals; Brain Neoplasms; Cell Line, Tumor; Cell Proliferation; Combined Modality Therapy; Enzyme Inhibitors; Glioma; Guanidines; Immunization; Immunotherapy, Adoptive; Interferon-gamma; Lymph Nodes; Lysine; Nitric Oxide Synthase Type II; Rats; Rats, Inbred F344; Spleen; Survival; T-Lymphocytes	2007
Inhibition of glioma cell line A-172 MMP activity and cell invasion in vitro by a nutrient mixture. Medical oncology (Northwood, London, England), 2007, Volume: 24, Issue:2 Topics: Acetylcysteine; Amino Acids; Antineoplastic Agents; Arginine; Ascorbic Acid; Camellia sinensis; Cell Line, Tumor; Cell Proliferation; Cell Survival; Collagen; Drug Combinations; Glioma; Humans; Laminin; Lysine; Matrix Metalloproteinase Inhibitors; Matrix Metalloproteinases; Neoplasm Invasiveness; Plant Extracts; Proline; Proteoglycans	2007
Modulation of substance P signaling by dipeptidyl peptidase-IV enzymatic activity in human glioma cell lines. Physiological research, 2008, Volume: 57, Issue:3 Topics: Brain Neoplasms; Calcium Signaling; Chemokine CXCL12; Dipeptidyl Peptidase 4; Dipeptidyl-Peptidase IV Inhibitors; Glioma; Humans; Lysine; Mifepristone; Oligopeptides; Pyrrolidines; Serine Proteinase Inhibitors; Substance P; Transfection; U937 Cells	2008
LDI-glycerol polyurethane implants exhibit controlled release of DB-67 and anti-tumor activity in vitro against malignant gliomas. Acta biomaterialia, 2008, Volume: 4, Issue:4 Topics: Camptothecin; Cell Death; Cell Line, Tumor; Delayed-Action Preparations; Drug Screening Assays, Antitumor; Glioma; Glycerol; Humans; Isocyanates; Lysine; Microscopy, Electron, Scanning; Organosilicon Compounds; Polyurethanes; Prostheses and Implants; Solutions; Spectrometry, Fluorescence; Spectroscopy, Fourier Transform Infrared; Tablets	2008
In vitro photodynamic effects of lysyl chlorin p6: cell survival, localization and ultrastructural changes. Photochemistry and photobiology, 1993, Volume: 58, Issue:5 Topics: Animals; Cell Survival; Cytoplasm; Dihematoporphyrin Ether; Dose-Response Relationship, Radiation; Glioma; Intracellular Membranes; Lasers; Light; Lysine; Microscopy, Electron; Microscopy, Fluorescence; Mitochondria; Photosensitizing Agents; Porphyrins; Rats; Tumor Cells, Cultured	1993
Non-amyloidogenic cleavage of the beta-amyloid precursor protein by an integral membrane metalloendopeptidase. The Journal of biological chemistry, 1994, Jan-28, Volume: 269, Issue:4 Topics: Alkaline Phosphatase; Alzheimer Disease; Amino Acid Sequence; Amyloid beta-Protein Precursor; Cell Line; Cell Membrane; Detergents; Enzyme Stability; Glioma; Humans; Kinetics; Lysine; Metalloendopeptidases; Models, Biological; Protease Inhibitors; Protein Processing, Post-Translational; Substrate Specificity; Transfection; Tumor Cells, Cultured	1994
Novel anti-brain tumor cytotoxins specific for cancer cells. Nature biotechnology, 1998, Volume: 16, Issue:5 Topics: Antineoplastic Agents; Brain Neoplasms; Carrier Proteins; Cell Division; Cytotoxins; Exotoxins; Glioma; Glutamic Acid; Humans; Interleukin-13; Interleukin-13 Receptor alpha1 Subunit; Lysine; Mutation; Plasmids; Pseudomonas aeruginosa; Receptors, Cell Surface; Receptors, Interleukin; Receptors, Interleukin-13; Recombinant Fusion Proteins; Tumor Cells, Cultured	1998
Thromboxane synthase regulates the migratory phenotype of human glioma cells. Neuro-oncology, 1999, Volume: 1, Issue:1 Topics: Arachidonic Acids; Aspirin; Astrocytes; Benzofurans; Brain Neoplasms; Cell Adhesion; Cell Movement; Enzyme Induction; Enzyme Inhibitors; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Glioma; GTP-Binding Proteins; Humans; Imidazoles; Indomethacin; Lysine; Models, Biological; Neoplasm Proteins; Neoplastic Stem Cells; Oligodendroglia; Pentanoic Acids; Phenotype; Pyridines; RNA, Messenger; RNA, Neoplasm; Signal Transduction; Thromboxane B2; Thromboxane-A Synthase; Tumor Cells, Cultured	1999
Effectiveness of a lysyl chlorin p6/chlorin p6 mixture in photodynamic therapy of the subcutaneous 9L glioma in the rat. Cancer research, 1992, Mar-01, Volume: 52, Issue:5 Topics: Animals; Drug Screening Assays, Antitumor; Glioma; Lysine; Male; Necrosis; Neoplasm Transplantation; Photochemotherapy; Porphyrins; Rats; Rats, Inbred F344; Skin; Skin Neoplasms	1992
Transport of leucine, lysine, glycine and aspartate in neuroblastoma C1300 and glioma C6 cells. Acta physiologica Scandinavica, 1987, Volume: 131, Issue:4 Topics: Animals; Aspartic Acid; Cell Line, Transformed; Glioma; Glycine; Humans; Leucine; Lysine; Neuroblastoma	1987