Compounds > lysine
Page last updated: 2024-08-17

lysine and Genetic Predisposition

lysine has been researched along with Genetic Predisposition in 97 studies

Research

Studies (97)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's3 (3.09)18.2507
2000's43 (44.33)29.6817
2010's43 (44.33)24.3611
2020's8 (8.25)2.80

Authors

AuthorsStudies
Akhtar, A; Chatterjee, A; Pessoa Rodrigues, C; Shvedunova, M; Stehle, T; Szymanski, W; Wiese, M1
Bernardini, JP; Cobbold, SA; Cotton, TR; Lechtenberg, BC; Richardson, LW; Wang, XS1
Fan, C; He, N; Min, F; Qin, B; Shi, Y; Zeng, T; Zeng, Y1
Mi, YY; Song, NH; Wang, ZJ; Yuan, W; Zhang, LF; Zhang, W; Zhu, LJ; Zuo, L1
Ahituv, N; Eckalbar, WL; Gray, RS; Khanshour, AM; Liu, Z; Makki, N; Rios, J; Ushiki, A; Wise, CA; Wu, J; Zhao, J1
Bararpour, N; Darrous, L; Froguel, P; Gasser, M; Gilardi, F; Kutalik, Z; Marques-Vidal, P; Porcu, E; Thomas, A; Waeber, G; Yengo, L1
Aglago, EK; Aleksandrova, K; Amiano, P; Bueno-de-Mesquita, B; Colorado-Yohar, SM; Dahm, CC; Fedirko, V; Freisling, H; Gram, IT; Gunter, MJ; Gurrea, AB; Heath, AK; Hughes, DJ; Jakszyn, P; Jenab, M; Jiao, L; Johnson, T; Katzke, V; Macciotta, A; Masala, G; Mayén, AL; Olsen, A; Perez-Cornago, A; Sánchez, MJ; Sandanger, T; Schalkwijk, CG; Schulze, MB; Sieri, S; Simeon, V; Skeie, G; Tjønneland, A; Tumino, R; Weiderpass, E1
Allis, CD; Barrows, D; Chen, X; Gillespie, ZB; Horth, C; Keogh, MC; Lu, C; Majewski, J; Marunde, MR; Popova, IK; Rosenbaum, P; Weinberg, DN1
Ling, L; Ruijuan, G; Xin, Y; Zefeng, K1
Hirschey, MD; Hu, X; Huynh, FK; Johnson, JD; Lin, Z1
Bu, C; Chen, Z; Cheng, Z; Han, C; He, L; Jin, T; Li, W; Liang, J; Liu, S; Liu, X; Liu, Y; Shang, Y; Sun, L; Xie, G; Xiong, Y; Xu, B; Yang, J; Yu, H; Yuan, S; Zhang, Y1
Gu, R; Huang, G; Lin, Y; Ma, D; Ma, X; Sheng, W; Xu, J1
Hannon, E; Marzi, SJ; Mill, J; Schalkwyk, LS1
Gomez, GVB; Lima, CSP; Lourenço, GJ; Moraes, AM; Oliveira, C; Rinck-Junior, JA; Torricelli, C1
Fine, DH; Furgang, D; Godboley, D; Sampathkumar, V; Toruner, GA; Velliyagounder, K1
Bourdon, V; Dreyfus, H; Eisinger, F; Extra, JM; Geneix, J; Gesta, P; Hassanein, M; Huiart, L; Jacquemier, J; Lidereau, R; Meynard, P; Noguchi, T; Nogues, C; Petrot, D; Peyrat, JP; Rabayrol, L; Sobol, H; Viens, P1
Hammami, B; Hamza-Chaffai, A; Kallel, I; Khlifi, R; Rebai, A1
Chen, G; Feng, Z; Lu, J; Zheng, L; Zou, D1
D'Argenio, V; Esposito, MV; Frisso, G; Gilder, JA; Salvatore, F1
Gao, CY; Li, BH; Li, JC; Liao, SQ; Liu, Y; Yin, YW; Zhang, LL; Zhang, M; Zhang, MJ1
Chen, W; He, Q; Lin, X; Ren, Z; Wang, F; Xing, X; Xu, J1
Hoffmann, GF; Kölker, S; Mohr, H; Okun, JG; Opp, S; Posset, R; Sauer, SW; Struys, EA; Völkl, A1
Chen, Y; Cui, L; Cui, Z; Li, M; Shang, R; Sun, Y; Xu, F1
Babizhayev, MA; Lankin, VZ; Nosikov, VV; Savel'yeva, EL; Sitnikov, VF; Strokov, IA; Yegorov, YE1
Blank, AE; Burgard, P; Koeller, DM; Kölker, S; Komatsuzaki, S; Mittelbronn, M; Okun, JG; Opp, S; Sauer, SW1
Dong, WG; Guo, XF; Lei, XF; Wang, J; Zeng, YP1
Chen, J; Duan, R; Liu, W; Qi, B; Zhang, M; Zhao, J1
Anttila, V; Bulik-Sullivan, B; Daly, MJ; Day, FR; Farh, K; Finucane, HK; Gusev, A; Lindstrom, S; Loh, PR; Neale, BM; Okada, Y; Patterson, N; Perry, JR; Price, AL; Purcell, S; Raychaudhuri, S; Reshef, Y; Ripke, S; Stahl, E; Trynka, G; Xu, H; Zang, C1
Abraham, BJ; Anders, L; Bramlett, K; Capasso, M; Crimmins, I; Diamond, M; Diskin, SJ; Durbin, AD; Gerhard, DS; Guidry Auvil, JM; Hakonarson, H; Hart, LS; Iolascon, A; Khan, J; Look, AT; Maris, JM; McDaniel, LD; Oldridge, DA; Rahman, N; Sussman, R; Tian, L; Wei, JS; Weichert-Leahey, N; Winter, C; Wood, AC; Young, RA; Zhang, S; Zhu, S1
Agnarsson, BA; Aittomäki, K; Andrulis, IL; Anton-Culver, H; Antoniou, AC; Bandera, EV; Banerjee, S; Barile, M; Barrowdale, D; Beckman, MW; Beeghly-Fadiel, A; Benitez, J; Berchuck, A; Bjorge, L; Blomqvist, C; Bogdanova, NV; Bojesen, SE; Bolla, MK; Borg, A; Borresen-Dale, AL; Brauch, H; Brenner, H; Broeks, A; Bruinsma, F; Brunet, J; Brüning, T; Burwinkel, B; Butterbach, K; Butzow, R; Buys, SS; Cai, H; Campbell, IG; Cannioto, R; Castillo, D; Chan, SB; Chang-Claude, J; Chenevix-Trench, G; Claes, KB; Collavoli, A; Cook, LS; Couch, FJ; Cox, A; Cramer, D; Cross, SS; Cunningham, JM; Czene, K; Daly, MB; Damiola, F; Darabi, H; Dennis, J; Devilee, P; Diez, O; Ding, YC; Doherty, JA; Domchek, SM; Dorfling, CM; Dörk, T; Dunning, AM; Easton, DF; Eccles, DM; Ellis, S; Eunjung, L; Fasching, PA; Feng, B; Figueroa, J; Flesch-Janys, D; Fletcher, O; Flyger, H; Foretova, L; Fostira, F; Friedman, E; Frost, D; Ganz, PA; Gao, YT; Garber, J; García-Closas, M; Gayther, S; Gerdes, AM; Giles, GG; Glasspool, R; Godwin, AK; Goldberg, MS; Goldgar, DE; González-Neira, A; Goode, EL; Goodman, MT; Greene, MH; Gronwald, J; Guénel, P; Hahnen, E; Haiman, CA; Hall, P; Hallberg, E; Hamann, U; Hansen, TV; Hart, SN; Healey, S; Heitz, F; Henderson, BE; Henriksson, K; Hildebrant, MA; Hogdall, C; Hogdall, E; Hogervorst, FB; Hopper, JL; Hosono, S; Hoya, Mde L; Hulick, PJ; Imyanitov, EN; Isaacs, C; Jakubowska, A; James, PA; Janavicius, R; Jensen, A; John, EM; Johnson, N; Jones, M; Kabisch, M; Karlan, BY; Khan, S; Kiemeney, LA; Kjaer, SK; Knight, JA; Konstantopoulou, I; Koppert, LB; Kosma, VM; Kristensen, V; Kupryjanczyk, J; Kwong, A; Laitman, Y; Lambrechts, D; Lazaro, C; Le, N; Lester, J; Levine, D; Li, J; Liang, D; Lindblom, A; Loud, JT; Lu, KH; Lubinski, J; Maerken, TV; Mai, PL; Mannermaa, A; Manoukian, S; Margolin, S; Marme, F; Massuger, LF; Matsuo, K; Maugard, C; Mazoyer, S; McGuffog, L; McNeish, I; Meeks, HD; Meindl, A; Menon, U; Michailidou, K; Milne, RL; Modugno, F; Moes-Sosnowska, J; Montagna, M; Monteiro, AN; Moysich, KB; Narod, S; Nathanson, KL; Ness, R; Neuhausen, SL; Nevanlinna, H; Neven, P; Nussbaum, RL; Offit, K; Öfverholm, A; Olah, E; Oliani, C; Olopade, OI; Olson, JE; Olson, SH; Osorio, A; Ouweland, AM; Park, SK; Pasini, BJ; Pearce, L; Pedersen, IS; Peissel, B; Peixoto, A; Pejovic, T; Pelttari, LM; Peterlongo, P; Pharoah, PD; Phelan, CM; Piedmonte, M; Poole, EM; Pylkäs, K; Radice, P; Ramus, SJ; Rantala, J; Rappaport-Feurhauser, C; Rennert, G; Riboli, E; Risch, H; Robson, M; Rossing, MA; Rudolph, A; Salvesen, HB; Sawyer, EJ; Schildkraut, J; Schmidt, MK; Schoemaker, MJ; Segura, PP; Senter, L; Shah, M; Shimelis, H; Siddiquil, N; Sieh, W; Simard, J; Singer, CF; Sinilnikova, OM; Slager, S; Song, H; Soucy, P; Southey, MC; Spurdle, AB; Stoppa-Lyonnet, D; Swerdlow, A; Teixeira, MR; Teo, SH; Terry, KL; Terry, MB; Tesoriero, A; Thomassen, M; Thompson, PJ; Tihomirova, L; Tischkowitz, M; Tollenaar, RA; Tomlinson, I; Torres, D; Truong, T; Tucker, K; Tung, N; Tworoger, SS; van Rensburg, EJ; Varon-Mateeva, R; Viel, A; Wang, Q; Wappenschmidt, B; Weitzel, JN; Wentzensen, N; Whittermore, AS; Winqvist, R; Woo, YL; Wu, A; Yoon, SY; Zheng, W1
Adam, A; Büttner, R; Dietlein, F; Ermolaeva, MA; Fernández-Majada, V; Komander, D; Pasparakis, M; Schell, M; Schumacher, B; Thomas, RK; Welz, PS1
Biancucci, M; Gius, D; Jiang, H; Kang, HJ; O'Callaghan, C; Park, SH; Principe, DR; Raparia, K; Satchell, KF; Song, HY; Vassilopoulos, A; Yan, Y1
Chung, HJ; Jewett, KA; Lee, KY; Man, HY; Tsai, NP; Zhu, J1
Clish, CB; Coresh, J; Fox, CS; Gerszten, RE; Hwang, SJ; Larson, MG; Levy, D; Li, M; McMahon, GM; O'Donnell, CJ; Rhee, EP; Tin, A; Yang, Q; Young, JH1
Feng, W; Miao, F; Min, A; Natarajan, R; Smith, DD; Zhang, L1
Baum, L; Chan, JC; Chan, WM; Chan, YM; Choy, KW; Fan, BJ; Fung, NS; Lam, DS; Li, H; Liu, DT; Louey, JW; Pang, CP1
Osredkar, J; Petrovic, D; Petrovic, MG; Saraga-Babić, M1
Arakaki, RF; Florez, JC; Goldstein, BJ; Hanson, RL; Jablonski, KA; Kahn, SE; Kitabchi, AE; Knowler, WC; Mason, CC; McAteer, JB; Moore, AF1
Bassi, S; Bergamini, F; Corradi, A; Iori, A; Migliore, S; Pongolini, S1
Baker, EK; Balcerczyk, A; Brasacchio, D; Brownlee, M; Calkin, AC; Cooper, ME; El-Osta, A; George, P; Okabe, J; Tikellis, C1
Lachman, HM; Locker, J; Pedrosa, E1
Budka, H; Ghetti, B; Haraszti, L; Horvath, S; Kovacs, GG; Majtenyi, K; Molnar, MJ; Murrell, JR; Spina, S1
Niwa, T; Shimazu, T; Takeshima, H; Ushijima, T; Yamashita, S1
Brajusković, G; Cadez, I; Dimitrijević, R; Dobricić, V; Keckarević, D; Keckarević-Marković, M; Kecmanović, M; Romac, S; Savić-Pavićević, D1
Biacabe, AG; Budka, H; Höftberger, R; Kapás, I; Kovacs, GG; László, L; Majtenyi, K; Meyronet, D; Perret-Liaudet, A; Quadrio, I; Sciot, R; Seguin, J; Streichenberger, N; Ströbel, T; Vandenberghe, R1
Bizzi, A; Bugiani, O; Capobianco, R; Carella, F; Cupidi, C; Di Fede, G; Giaccone, G; Giovagnoli, A; Magoni, M; Mangieri, M; Marcon, G; Mazzoleni, G; Morbin, M; Padovani, A; Patruno, GM; Puoti, G; Romorini, A; Rossi, G; Salmaggi, A; Tagliavini, F1
Abate, N; Adams-Huet, B; Bell, J; Chandalia, M; Grundy, SM; Szuszkiewicz, M; Vazquez, M1
Ataei, F; Bakhtiyari, S; Gerayesh-Nejad, S; Gulkho, S; Hanachi, P; Larijani, B; Meshkani, R; Mohammadi, M; Mohammadtaghvaei, N; Parvaneh, L; Saberi, H; Zargari, M1
Nastalek, M; Nishiyama, C; Okumura, K; Potaczek, DP; Undas, A; Wojas-Pelc, A1
Catamo, E; Crovella, S; Fabris, A; Pontillo, A; Vendramin, A1
Hsiao, HH; Hsu, JF; Lee, CP; Lin, SF; Liu, YC; Tsai, HJ1
Cichon, S; Deufel, T; Kiehntopf, M; Koch, K; Mühleisen, TW; Nenadic, I; Nöthen, MM; Reichenbach, JR; Rietschel, M; Roebel, M; Sauer, H; Schachtzabel, C; Schlösser, RG; Schultz, CC; Wagner, G1
Chen, YG; Hao, PP; Wang, JL; Wang, XL; Zhang, Y1
Arai, M; Arinami, T; Ichikawa, T; Itokawa, M; Iwayama, Y; Maekawa, M; Miyashita, M; Toyosima, M; Toyota, T; Yoshikawa, T1
Bhowmik, AD; Chaudhuri, K; Mukherjee, S; Mukhopadhyay, K; Ray, JG; Roychoudhury, P1
Bonvicini, C; Bucossi, S; Manfellotto, D; Mariani, S; Migliore, S; Polimanti, R; Rossini, PM; Salustri, C; Squitti, R; Ventriglia, M; Vernieri, F1
Rezaei, Z; Saadat, I; Saadat, M1
Greenlee, JJ; Hamir, AN; Kunkle, RA; Nicholson, EM; Zhang, X1
Chen, Y; Hong, XS; Jing, X; Lei, M; Liu, X; Luo, XP; Xiong, XD; Zeng, LQ1
Croul, S; Dubuc, AM; Eberhart, CG; Hawkins, C; Hielscher, T; Jones, DT; Jones, SJ; Kool, M; Korshunov, A; Marra, MA; Mendez-Lago, M; Morrissy, AS; Northcott, PA; Peacock, J; Pfister, SM; Ramaswamy, V; Remke, M; Rolider, A; Rutka, JT; Shih, D; Taylor, MD; Unterberger, A; Vibhakar, R; Wang, X; Weiss, WA; Witt, H; Zhan, SH1
Mayer, MP; Melchers, I; Roth, S; Rzepka, R; Willcox, N1
Garcia, YR; Krolick, KA; Pothitakis, JC1
Ding, Q; Dong, LY; Lu, JY; Sun, ZJ; Wang, XN; Zhao, YY1
Akhayat, O; Belmouden, A; Brézin, A; Garchon, HJ; Melki, R1
Abate, N; Cabo-Chan, A; Carulli, L; Chandalia, M; Grundy, SM; Snell, PG1
Faisel, F; Heinonen, S; Helisalmi, S; Hiltunen, M; Laasanen, J; Punnonen, K; Romppanen, EL; Salonen, JT1
Chapman, RW; Cullen, SN; Jewell, DP; Li, JH; Yang, X1
Bohren, KM; Gabbay, KH; Nadkarni, V; Owerbach, D; Song, JH1
Higuchi, S; Kamakura, K; Masaki, T; Matsushita, S; Mochizuki, H; Yokoyama, A1
Eriksson, J; Hämäläinen, H; Ilanne-Parikka, P; Keinänen-Kiukaanniemi, S; Laakso, M; Laukkanen, O; Lindström, J; Pihlajamäki, J; Tuomilehto, J; Uusitupa, M; Valle, TT1
Bar Meir, S; Fidder, HH; Figer, A; Friedman, E; Zidan, J1
Fujimoto, M; Fukami, M; Hasegawa, T; Koitabashi, Y; Ogata, T; Soneda, S1
Heinonen, S; Helisalmi, S; Hiltunen, M; Laakso, M; Saarela, T1
DeKosky, ST; Feingold, E; Kamboh, MI; Minster, RL; Sundar, PD1
Bertini, E; Boldrini, R; D'Amico, A; Feng, JJ; Graziano, C; Jacques, A; Laing, N; Limongelli, G; Marston, SB; Nowak, KJ; Pacileo, G; Petrini, S; Porfirio, B; Santorelli, FM; Sewry, CA1
Allen-Auerbach, M; Doostzadeh, J; Langston, JW; Schüle, B; Tetrud, JW1
Milutinović, A; Petrovic, D1
Altshuler, D; Dabelea, D; Florez, JC; Franks, PW; Hamman, RF; Jablonski, KA; Kahn, SE; Knowler, WC; Nathan, DM1
Beck, M; Sendtner, M; Toyka, KV1
Aasly, JO; Farrer, MJ; Haugarvoll, K; Ross, OA; Toft, M; White, LR1
Barkhof, F; Hooper-van Veen, T; Koper, JW; Polman, CH; Uitdehaag, BM; van Rossum, EF; van Winsen, LM1
Christiani, DC; Gonzalez, E; Mahiuddin, G; McCarty, KM; Quamruzzaman, Q; Rahman, M; Ryan, L; Smith, TJ; Su, L; Zhou, W1
Cheng, KC; Connor, JR; Goodman, SI; Housman, C; Jacobs, RE; LaNoue, K; Lazovic, J; O'Callaghan, JP; Simpson, I; Woontner, M; Zinnanti, WJ1
Benndorf, K; Figulla, HR; Hensellek, S; Prochnau, D; Surber, R; Werner, GS; Zimmer, T1
Bai, C; Fukao, T; Kaneko, H; Kasahara, K; Kato, Z; Kimata, K; Kondo, N; Matsui, E; Ohnishi, H1
Hasegawa, Y; Kimura, M; Komai, K; Samuraki, M; Terada, N; Yamada, M; Yamaguchi, S1
Ahari, SE; Bahar, M; Banoei, MM; Houshmand, M; Kasraie, S; Moin, M; Panahi, MS; Shariati, P1
Kondapaneni, M; Laubach, VE; McGregor, JR; Salvemini, D; Samlowski, WE1
Dwyer, E; Itescu, S; Rose, S; Winchester, R1
Dybdahl, M; Frentz, G; Nexø, BA; Vogel, U; Wallin, H1
Bogdan, C; Deckert-Schlüter, M; Lorenz, E; Meyer, T; Röllinghoff, M; Schlüter, D1
Bartell, SM; Faustman, EM; Omenn, GS; Ponce, RA; Takaro, TK; Zerbe, RO1
Billiau, A; Matthys, P; Thielemans, L; Vermeire, K1
Haas, OA; Muhr, D; Niederle, B; Scheuba, C; Schlegl, R; Vierhapper, H; Wagner, T; Weinhaeusel, A1
Degen, SJ; Jenkins, ML; Smirnow, D; Sun, WY1
Amicosante, M; Arroyo, J; Berretta, F; Colizzi, V; Lechler, R; Lombardi, G; Saltini, C; Sanarico, N1

Reviews

5 review(s) available for lysine and Genetic Predisposition

ArticleYear
Association between intercellular adhesion molecule-1 gene K469E polymorphism and the risk of stroke in a Chinese population: a meta-analysis.
    The International journal of neuroscience, 2015, Volume: 125, Issue:3

    Topics: Asian People; Confidence Intervals; Databases, Bibliographic; Female; Genetic Association Studies; Genetic Predisposition to Disease; Glutamine; Humans; Intercellular Adhesion Molecule-1; Lysine; Male; Odds Ratio; Polymorphism, Single Nucleotide; Risk Factors; Stroke

2015
The Glu504Lys polymorphism of aldehyde dehydrogenase 2 contributes to development of coronary artery disease.
    The Tohoku journal of experimental medicine, 2014, Volume: 234, Issue:2

    Topics: Aldehyde Dehydrogenase; Aldehyde Dehydrogenase, Mitochondrial; Alleles; Asian People; Cardiovascular Diseases; Coronary Artery Disease; Genetic Predisposition to Disease; Glutamic Acid; Humans; Inflammation; Lysine; Nitric Oxide Synthase Type III; Oxidative Stress; Polymorphism, Genetic; Risk Factors

2014
XPD Lys751Gln polymorphisms and the risk of esophageal cancer: an updated meta-analysis.
    Internal medicine (Tokyo, Japan), 2015, Volume: 54, Issue:3

    Topics: Case-Control Studies; DNA Repair; Esophageal Neoplasms; Genetic Predisposition to Disease; Glutamine; Humans; Lysine; Odds Ratio; Polymorphism, Single Nucleotide; Prognosis; Risk Factors; Xeroderma Pigmentosum Group D Protein

2015
Genetic predisposition to neuroblastoma mediated by a LMO1 super-enhancer polymorphism.
    Nature, 2015, Dec-17, Volume: 528, Issue:7582

    Topics: Acetylation; Alleles; Allelic Imbalance; Binding Sites; DNA-Binding Proteins; Enhancer Elements, Genetic; Epigenomics; GATA3 Transcription Factor; Gene Expression Regulation, Neoplastic; Genetic Predisposition to Disease; Genome-Wide Association Study; Genotype; Histones; Humans; Introns; LIM Domain Proteins; Lysine; Neuroblastoma; Organ Specificity; Polymorphism, Single Nucleotide; Reproducibility of Results; Transcription Factors

2015
Meta-analysis of aldehyde dehydrogenase 2 gene polymorphism and Alzheimer's disease in East Asians.
    The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques, 2011, Volume: 38, Issue:3

    Topics: Aged; Aged, 80 and over; Aldehyde Dehydrogenase; Aldehyde Dehydrogenase, Mitochondrial; Alzheimer Disease; Apolipoprotein E4; Asia, Eastern; Confidence Intervals; Databases, Bibliographic; Female; Gene Frequency; Genetic Predisposition to Disease; Genotype; Glutamic Acid; Humans; Lysine; Male; Odds Ratio; Polymorphism, Single Nucleotide

2011

Trials

3 trial(s) available for lysine and Genetic Predisposition

ArticleYear
The association of ENPP1 K121Q with diabetes incidence is abolished by lifestyle modification in the diabetes prevention program.
    The Journal of clinical endocrinology and metabolism, 2009, Volume: 94, Issue:2

    Topics: Chromans; Combined Modality Therapy; Diabetes Mellitus, Type 2; Exercise Therapy; Female; Gene Frequency; Genetic Linkage; Genetic Predisposition to Disease; Glutamic Acid; Humans; Hypoglycemic Agents; Incidence; Lysine; Male; Metformin; Middle Aged; Phosphoric Diester Hydrolases; Polymorphism, Single Nucleotide; Pyrophosphatases; Risk Reduction Behavior; Thiazolidinediones; Troglitazone

2009
Polymorphisms of the SUR1 (ABCC8) and Kir6.2 (KCNJ11) genes predict the conversion from impaired glucose tolerance to type 2 diabetes. The Finnish Diabetes Prevention Study.
    The Journal of clinical endocrinology and metabolism, 2004, Volume: 89, Issue:12

    Topics: Adenine; Adult; Alleles; ATP-Binding Cassette Transporters; Confidence Intervals; Diabetes Mellitus, Type 2; Disease Progression; Genetic Predisposition to Disease; Glucose Intolerance; Guanine; Haplotypes; Humans; Linkage Disequilibrium; Lysine; Middle Aged; Odds Ratio; Polymorphism, Genetic; Potassium Channels; Potassium Channels, Inwardly Rectifying; Promoter Regions, Genetic; Receptors, Drug; Sulfonylurea Receptors

2004
Type 2 diabetes-associated missense polymorphisms KCNJ11 E23K and ABCC8 A1369S influence progression to diabetes and response to interventions in the Diabetes Prevention Program.
    Diabetes, 2007, Volume: 56, Issue:2

    Topics: Alleles; ATP-Binding Cassette Transporters; Diabetes Mellitus, Type 2; Disease Progression; Female; Genetic Predisposition to Disease; Genotype; Glucose Intolerance; Humans; Hypoglycemic Agents; Insulin; Insulin Secretion; Lysine; Male; Metformin; Middle Aged; Mutation, Missense; Polymorphism, Genetic; Potassium Channels; Potassium Channels, Inwardly Rectifying; Proportional Hazards Models; Receptors, Drug; Sulfonylurea Receptors; Treatment Outcome

2007

Other Studies

89 other study(ies) available for lysine and Genetic Predisposition

ArticleYear
Histone H4 lysine 16 acetylation controls central carbon metabolism and diet-induced obesity in mice.
    Nature communications, 2021, 10-27, Volume: 12, Issue:1

    Topics: Acetylation; Adipocytes; Adipose Tissue; Amino Acids; Animals; Carbon; Diabetes Mellitus, Type 2; Diet, High-Fat; Gene Expression Regulation; Genetic Predisposition to Disease; Glucose; Glucose Transporter Type 4; Haploinsufficiency; Histone Acetyltransferases; Histones; Lipid Metabolism; Lysine; Mice; Obesity; PPAR gamma

2021
Structural basis of K63-ubiquitin chain formation by the Gordon-Holmes syndrome RBR E3 ubiquitin ligase RNF216.
    Molecular cell, 2022, 02-03, Volume: 82, Issue:3

    Topics: Allosteric Regulation; Binding Sites; Catalysis; Cerebellar Ataxia; Crystallography, X-Ray; Genetic Predisposition to Disease; Gonadotropin-Releasing Hormone; HEK293 Cells; Humans; Hypogonadism; Loss of Function Mutation; Lysine; Models, Molecular; Phenotype; Phosphorylation; Protein Binding; Protein Conformation; Protein Processing, Post-Translational; Structure-Activity Relationship; Ubiquitin-Protein Ligases; Ubiquitination

2022
Carbamazepine-modified HLA-A*24:02-bound peptidome: Implication of CORO1A in skin rash.
    International immunopharmacology, 2022, Volume: 109

    Topics: Anticonvulsants; Carbamazepine; Drug Hypersensitivity; Exanthema; Genetic Predisposition to Disease; HLA-A24 Antigen; HLA-B Antigens; HLA-B15 Antigen; Humans; Lysine; Microfilament Proteins; Peptides; Stevens-Johnson Syndrome

2022
MMP-8 C-799 T, Lys460Thr, and Lys87Glu variants are not related to risk of cancer.
    BMC medical genetics, 2019, 10-21, Volume: 20, Issue:1

    Topics: Genetic Predisposition to Disease; Glutamic Acid; Humans; Lysine; Matrix Metalloproteinase 8; Neoplasms; Polymorphism, Single Nucleotide; Threonine

2019
Genomic characterization of the adolescent idiopathic scoliosis-associated transcriptome and regulome.
    Human molecular genetics, 2021, 01-21, Volume: 29, Issue:22

    Topics: Acetylation; Adolescent; Child; DNA-Binding Proteins; Female; Genetic Predisposition to Disease; Genome-Wide Association Study; Genomics; Histones; Humans; Lysine; Male; Muscle, Skeletal; Receptors, G-Protein-Coupled; RNA-Seq; Scoliosis; Spine; Transcriptome

2021
Triangulating evidence from longitudinal and Mendelian randomization studies of metabolomic biomarkers for type 2 diabetes.
    Scientific reports, 2021, 03-18, Volume: 11, Issue:1

    Topics: Adult; Aged; Betaine; Biomarkers; Carnitine; Case-Control Studies; Diabetes Mellitus, Type 2; Early Diagnosis; Female; Genetic Predisposition to Disease; Glutamic Acid; Humans; Leucine; Lysine; Male; Mannose; Mendelian Randomization Analysis; Metabolome; Middle Aged; Valine

2021
Plasma concentrations of advanced glycation end-products and colorectal cancer risk in the EPIC study.
    Carcinogenesis, 2021, 05-28, Volume: 42, Issue:5

    Topics: Adult; Aged; Chromatography, Liquid; Cohort Studies; Colorectal Neoplasms; Female; Genetic Association Studies; Genetic Predisposition to Disease; Glycation End Products, Advanced; Humans; Imidazoles; Lysine; Male; Middle Aged; Odds Ratio; Ornithine; Tandem Mass Spectrometry

2021
Two competing mechanisms of DNMT3A recruitment regulate the dynamics of de novo DNA methylation at PRC1-targeted CpG islands.
    Nature genetics, 2021, Volume: 53, Issue:6

    Topics: Animals; Catalysis; Cell Line; CpG Islands; DNA (Cytosine-5-)-Methyltransferases; DNA Methylation; DNA Methyltransferase 3A; Genetic Predisposition to Disease; Genome, Human; Histones; Humans; Lysine; Mice; Mutation; Nucleosomes; Polycomb-Group Proteins; Protein Domains; Ubiquitination

2021
Association between NF-kB polymorphism and age-related macular degeneration in a high-altitude population.
    PloS one, 2021, Volume: 16, Issue:6

    Topics: Aged; Altitude; Carotenoids; Case-Control Studies; China; Female; Gene Frequency; Genetic Predisposition to Disease; Genotype; Humans; Lysine; Macular Degeneration; Male; Middle Aged; NF-kappa B; Polymorphism, Single Nucleotide

2021
Loss of sirtuin 4 leads to elevated glucose- and leucine-stimulated insulin levels and accelerated age-induced insulin resistance in multiple murine genetic backgrounds.
    Journal of inherited metabolic disease, 2018, Volume: 41, Issue:1

    Topics: Age Factors; Animals; Biomarkers; Blood Glucose; Female; Genetic Predisposition to Disease; In Vitro Techniques; Insulin; Insulin Resistance; Leucine; Lipid Metabolism; Lysine; Male; Metabolism, Inborn Errors; Mice, 129 Strain; Mice, Inbred C57BL; Mice, Knockout; Mitochondrial Proteins; Phenotype; Protein Processing, Post-Translational; Sirtuins; Up-Regulation

2018
Chromodomain Protein CDYL Acts as a Crotonyl-CoA Hydratase to Regulate Histone Crotonylation and Spermatogenesis.
    Molecular cell, 2017, Sep-07, Volume: 67, Issue:5

    Topics: Acyl Coenzyme A; Animals; Co-Repressor Proteins; Enoyl-CoA Hydratase; Fertility; Genetic Predisposition to Disease; HeLa Cells; Histone Acetyltransferases; Histones; Humans; Hydro-Lyases; Infertility, Male; Kinetics; Lysine; Male; Mice, Inbred C57BL; Mice, Transgenic; Phenotype; Protein Domains; Protein Processing, Post-Translational; Proteins; RNA Interference; Sf9 Cells; Sperm Count; Sperm Motility; Spermatogenesis; Spermatozoa; Testis; Transfection

2017
The role of histone modification and a regulatory single-nucleotide polymorphism (rs2071166) in the Cx43 promoter in patients with TOF.
    Scientific reports, 2017, 09-05, Volume: 7, Issue:1

    Topics: Acetylation; Alleles; Asian People; Biomarkers; Connexin 43; Genetic Predisposition to Disease; Genotype; Histone Code; Histones; Humans; Immunohistochemistry; Lysine; Phenotype; Polymorphism, Single Nucleotide; Promoter Regions, Genetic; Protein Binding; Retinoid X Receptor alpha; Risk Factors; RNA, Messenger; Sequence Analysis, DNA; Tetralogy of Fallot

2017
Genetic risk variants for brain disorders are enriched in cortical H3K27ac domains.
    Molecular brain, 2019, 01-28, Volume: 12, Issue:1

    Topics: Acetylation; Brain Diseases; Entorhinal Cortex; Genetic Predisposition to Disease; Genetic Variation; Histones; Humans; Inheritance Patterns; Lysine; Risk Factors

2019
Influence of functional variants Asp312Asn and Lys751Gln of Xeroderma Pigmentosum Group D (XPD) and Glutathione S-transferase Mu 1 (GSTM1) and Theta 1 (GSTT1) genes on cutaneous melanoma susceptibility and prognosis.
    Experimental dermatology, 2019, Volume: 28, Issue:5

    Topics: Aged; Asparagine; Aspartic Acid; Cell Survival; Disease-Free Survival; Genetic Predisposition to Disease; Genetic Variation; Genotype; Glutamine; Glutathione Transferase; Humans; Lysine; Melanoma; Middle Aged; Prognosis; Proportional Hazards Models; Skin Neoplasms; Treatment Outcome; Xeroderma Pigmentosum

2019
A lactotransferrin single nucleotide polymorphism demonstrates biological activity that can reduce susceptibility to caries.
    Infection and immunity, 2013, Volume: 81, Issue:5

    Topics: Analysis of Variance; Anti-Infective Agents; Dental Caries; Dental Caries Susceptibility; Genetic Predisposition to Disease; Genotype; Humans; Lactoferrin; Lysine; Polymorphism, Single Nucleotide; Saliva; Streptococcus mutans

2013
Prediction of BRCA1 germ-line mutation status in patients with breast cancer using histoprognosis grade, MS110, Lys27H3, vimentin, and KI67.
    Pathobiology : journal of immunopathology, molecular and cellular biology, 2013, Volume: 80, Issue:5

    Topics: BRCA1 Protein; Breast Neoplasms; DNA Mutational Analysis; Female; Genetic Predisposition to Disease; Genetic Testing; Germ-Line Mutation; Histones; Humans; Immunohistochemistry; Ki-67 Antigen; Logistic Models; Lysine; Multivariate Analysis; Neoplasm Grading; Patient Selection; Phenotype; Predictive Value of Tests; Prognosis; Reproducibility of Results; Tissue Array Analysis; Vimentin

2013
DNA repair gene polymorphisms and risk of head and neck cancer in the Tunisian population.
    Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology, 2014, Volume: 43, Issue:3

    Topics: Adenine; Adolescent; Adult; Aged; Aged, 80 and over; Alcohol Drinking; Arginine; Case-Control Studies; DNA Helicases; DNA Repair; DNA Repair Enzymes; DNA-Binding Proteins; Female; Gene-Environment Interaction; Genetic Predisposition to Disease; Glutamine; Guanine; Head and Neck Neoplasms; Humans; Lysine; Male; Middle Aged; Occupational Exposure; Polymorphism, Restriction Fragment Length; Polymorphism, Single Nucleotide; Risk Factors; Smoking; X-ray Repair Cross Complementing Protein 1; Xeroderma Pigmentosum Group D Protein; Young Adult

2014
Synergistic effect of LEP and LEPR gene polymorphism on body mass index in a Chinese population.
    Obesity research & clinical practice, 2013, Volume: 7, Issue:6

    Topics: Adult; Alleles; Arginine; Asian People; Asparagine; Body Mass Index; China; Female; Genetic Predisposition to Disease; Genotype; Humans; Leptin; Logistic Models; Lysine; Male; Obesity; Polymerase Chain Reaction; Polymorphism, Single Nucleotide; Polymorphism, Single-Stranded Conformational; Prevalence; Receptors, Leptin; Risk Factors; Waist-Hip Ratio

2013
Should a BRCA2 stop codon human variant, usually considered a polymorphism, be classified as a predisposing mutation?
    Cancer, 2014, May-15, Volume: 120, Issue:10

    Topics: Aged; BRCA2 Protein; Breast Neoplasms; Codon, Terminator; Female; Genetic Predisposition to Disease; Genotype; Germ-Line Mutation; Humans; Lysine; Male; Middle Aged; Neoplasms; Polymorphism, Genetic

2014
Associations of a polymorphism in the intercellular adhesion molecule-1 (ICAM1) gene and ICAM1 serum levels with migraine in a Chinese Han population.
    Journal of the neurological sciences, 2014, Oct-15, Volume: 345, Issue:1-2

    Topics: Adolescent; Adult; Asian People; Female; Gene Frequency; Genetic Association Studies; Genetic Predisposition to Disease; Genotype; Glutamic Acid; Humans; Intercellular Adhesion Molecule-1; Logistic Models; Lysine; Male; Middle Aged; Migraine Disorders; Polymorphism, Single Nucleotide; Risk Factors; RNA, Messenger; Young Adult

2014
Understanding cerebral L-lysine metabolism: the role of L-pipecolate metabolism in Gcdh-deficient mice as a model for glutaric aciduria type I.
    Journal of inherited metabolic disease, 2015, Volume: 38, Issue:2

    Topics: Amino Acid Metabolism, Inborn Errors; Animals; Brain; Brain Diseases, Metabolic; Deamination; Disease Models, Animal; Genetic Predisposition to Disease; Glutaryl-CoA Dehydrogenase; Liver; Lysine; Mice, Knockout; Oxidation-Reduction; Oxidoreductases Acting on CH-NH Group Donors; Peroxisomes; Phenotype; Pipecolic Acids

2015
The Role of Oxidative Stress in Diabetic Neuropathy: Generation of Free Radical Species in the Glycation Reaction and Gene Polymorphisms Encoding Antioxidant Enzymes to Genetic Susceptibility to Diabetic Neuropathy in Population of Type I Diabetic Patient
    Cell biochemistry and biophysics, 2015, Volume: 71, Issue:3

    Topics: Adult; Antioxidants; Diabetes Mellitus, Type 1; Diabetic Neuropathies; Female; Genetic Predisposition to Disease; Glycation End Products, Advanced; Humans; Lysine; Male; Oxidative Stress; Polymorphism, Genetic; Reactive Oxygen Species; Superoxides; Young Adult

2015
Multifactorial modulation of susceptibility to l-lysine in an animal model of glutaric aciduria type I.
    Biochimica et biophysica acta, 2015, Volume: 1852, Issue:5

    Topics: Aconitate Hydratase; Amino Acid Metabolism, Inborn Errors; Animals; Brain; Brain Diseases, Metabolic; Diet; Disease Models, Animal; Dose-Response Relationship, Drug; Energy Metabolism; Female; Genetic Predisposition to Disease; Glutarates; Glutaryl-CoA Dehydrogenase; Glyceraldehyde-3-Phosphate Dehydrogenases; Ketoglutarate Dehydrogenase Complex; Lysine; Male; Mice, 129 Strain; Mice, Inbred C57BL; Mice, Knockout; Risk Factors; Sex Factors; Spectrophotometry

2015
A novel mutation of GATA4 (K300T) associated with familial atrial septal defect.
    Gene, 2016, Jan-10, Volume: 575, Issue:2 Pt 2

    Topics: Adolescent; Adult; Asian People; Child; China; Female; GATA4 Transcription Factor; Genetic Predisposition to Disease; Heart Septal Defects, Atrial; Humans; Lysine; Male; Middle Aged; Mutation; Pedigree; Penetrance; Sequence Analysis, DNA; Young Adult

2016
Partitioning heritability by functional annotation using genome-wide association summary statistics.
    Nature genetics, 2015, Volume: 47, Issue:11

    Topics: Algorithms; Computer Simulation; Disease; Female; Gene Frequency; Genetic Predisposition to Disease; Genome-Wide Association Study; Histones; Humans; Inheritance Patterns; Lysine; Male; Methylation; Models, Genetic; Polymorphism, Single Nucleotide

2015
BRCA2 Polymorphic Stop Codon K3326X and the Risk of Breast, Prostate, and Ovarian Cancers.
    Journal of the National Cancer Institute, 2016, Volume: 108, Issue:2

    Topics: Adult; Aged; BRCA2 Protein; Breast Neoplasms; Codon, Terminator; Female; Genetic Predisposition to Disease; Heterozygote; Humans; Logistic Models; Lysine; Male; Middle Aged; Neoplasm Invasiveness; Odds Ratio; Ovarian Neoplasms; Polymorphism, Single Nucleotide; Prostatic Neoplasms; Risk Assessment; Risk Factors

2016
The tumour suppressor CYLD regulates the p53 DNA damage response.
    Nature communications, 2016, 08-26, Volume: 7

    Topics: Animals; Apoptosis; Azoxymethane; Caenorhabditis elegans; Caenorhabditis elegans Proteins; Carcinogenesis; Cysteine Endopeptidases; Deubiquitinating Enzyme CYLD; DNA Damage; DNA Repair; Female; Genetic Predisposition to Disease; Intestinal Neoplasms; Lysine; Male; Mice; Mice, Transgenic; Signal Transduction; Skin Neoplasms; Tumor Suppressor Protein p53; Ubiquitination

2016
SIRT2 deletion enhances KRAS-induced tumorigenesis in vivo by regulating K147 acetylation status.
    Oncotarget, 2016, Dec-06, Volume: 7, Issue:49

    Topics: Acetylation; Adenocarcinoma; Adenocarcinoma of Lung; Animals; Cell Proliferation; Cell Transformation, Neoplastic; Gene Deletion; Gene Expression Regulation, Neoplastic; Genetic Predisposition to Disease; HCT116 Cells; HEK293 Cells; Humans; Lung Neoplasms; Lysine; Male; Mice; Mice, Knockout; Mice, Nude; Mutation; NIH 3T3 Cells; Pancreatic Neoplasms; Phenotype; Protein Processing, Post-Translational; Proto-Oncogene Proteins p21(ras); Signal Transduction; Sirtuin 2; Time Factors; Tumor Burden

2016
Epilepsy-associated gene Nedd4-2 mediates neuronal activity and seizure susceptibility through AMPA receptors.
    PLoS genetics, 2017, Volume: 13, Issue:2

    Topics: 14-3-3 Proteins; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amino Acid Sequence; Animals; Animals, Newborn; Blotting, Western; Cells, Cultured; Endosomal Sorting Complexes Required for Transport; Epilepsy; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Genetic Predisposition to Disease; HEK293 Cells; Humans; Lysine; Male; Mice, Knockout; Microscopy, Confocal; Mutation, Missense; Nedd4 Ubiquitin Protein Ligases; Neurons; Quinoxalines; Receptors, AMPA; Seizures; Ubiquitin-Protein Ligases

2017
Urinary metabolites along with common and rare genetic variations are associated with incident chronic kidney disease.
    Kidney international, 2017, Volume: 91, Issue:6

    Topics: Aged; Amino Acid Transport Systems, Basic; Amino Acids; Biomarkers; Case-Control Studies; Chi-Square Distribution; Female; Genetic Predisposition to Disease; Glycine; Histidine; Humans; Incidence; Logistic Models; Lysine; Male; Mass Spectrometry; Massachusetts; Metabolomics; Middle Aged; Odds Ratio; Oligonucleotide Array Sequence Analysis; omega-N-Methylarginine; Phenotype; Polymorphism, Single Nucleotide; Proportional Hazards Models; Prospective Studies; Protective Factors; Renal Insufficiency, Chronic; Risk Assessment; Risk Factors; Urinalysis

2017
Lymphocytes from patients with type 1 diabetes display a distinct profile of chromatin histone H3 lysine 9 dimethylation: an epigenetic study in diabetes.
    Diabetes, 2008, Volume: 57, Issue:12

    Topics: Adolescent; Adult; Child; Child, Preschool; Chromatin; Cohort Studies; Diabetes Mellitus, Type 1; Environment; Epigenesis, Genetic; Genetic Predisposition to Disease; Histones; Humans; Insulin-Secreting Cells; Lymphocytes; Lysine; Middle Aged; Oligonucleotide Array Sequence Analysis; Polymerase Chain Reaction; T-Lymphocytes; Young Adult

2008
EDN1 Lys198Asn is associated with diabetic retinopathy in type 2 diabetes.
    Molecular vision, 2008, Sep-15, Volume: 14

    Topics: Age of Onset; Aged; Asparagine; Case-Control Studies; China; Diabetes Mellitus, Type 2; Diabetic Retinopathy; Endothelin-1; Female; Gene Frequency; Genetic Predisposition to Disease; Genotype; Humans; Hypertension; Lysine; Male; Middle Aged; Odds Ratio; Polymorphism, Single Nucleotide; Regression Analysis

2008
K469E polymorphism of the intracellular adhesion molecule 1 gene is associated with proliferative diabetic retinopathy in Caucasians with type 2 diabetes.
    Clinical & experimental ophthalmology, 2008, Volume: 36, Issue:5

    Topics: Aged; Alanine; Case-Control Studies; Cross-Sectional Studies; Diabetes Mellitus, Type 2; Diabetic Retinopathy; Female; Genetic Predisposition to Disease; Genotype; Glutamic Acid; Glycine; Humans; Intercellular Adhesion Molecule-1; Lysine; Male; Middle Aged; Polymorphism, Genetic; Slovenia; White People

2008
Prion protein genotypes of Italian sheep breeds with lysine-171 and phenylalanine-141 detection.
    Veterinary microbiology, 2009, May-28, Volume: 137, Issue:1-2

    Topics: Alleles; Amino Acid Sequence; Amino Acid Substitution; Animals; Genetic Predisposition to Disease; Genotype; Italy; Lysine; Phenylalanine; Prions; Scrapie; Sheep

2009
Hyperglycemia induces a dynamic cooperativity of histone methylase and demethylase enzymes associated with gene-activating epigenetic marks that coexist on the lysine tail.
    Diabetes, 2009, Volume: 58, Issue:5

    Topics: Animals; Cattle; Diabetic Angiopathies; DNA Methylation; DNA Primers; DNA, Complementary; Endothelium, Vascular; Genetic Predisposition to Disease; Histone Methyltransferases; Histone-Lysine N-Methyltransferase; Humans; Hyperglycemia; Lysine; Reverse Transcriptase Polymerase Chain Reaction; RNA

2009
Survey of schizophrenia and bipolar disorder candidate genes using chromatin immunoprecipitation and tiled microarrays (ChIP-chip).
    Journal of neurogenetics, 2009, Volume: 23, Issue:3

    Topics: Bipolar Disorder; Brain; Carrier Proteins; Catechol O-Methyltransferase; Chromatin Immunoprecipitation; Cyclic Nucleotide Phosphodiesterases, Type 4; D-Amino-Acid Oxidase; Dysbindin; Dystrophin-Associated Proteins; Fetus; Genetic Predisposition to Disease; Histones; Humans; Intracellular Signaling Peptides and Proteins; Lysine; Microarray Analysis; Nerve Tissue Proteins; Neuregulin-1; Schizophrenia

2009
TARDBP variation associated with frontotemporal dementia, supranuclear gaze palsy, and chorea.
    Movement disorders : official journal of the Movement Disorder Society, 2009, Sep-15, Volume: 24, Issue:12

    Topics: Chorea; DNA Mutational Analysis; DNA-Binding Proteins; Family Health; Female; Frontotemporal Dementia; Genetic Predisposition to Disease; Glutamic Acid; Humans; Lysine; Magnetic Resonance Imaging; Male; Middle Aged; Mutation; Neuropsychological Tests; Supranuclear Palsy, Progressive; Tomography Scanners, X-Ray Computed

2009
The presence of RNA polymerase II, active or stalled, predicts epigenetic fate of promoter CpG islands.
    Genome research, 2009, Volume: 19, Issue:11

    Topics: Cell Line; Cell Line, Tumor; Chromatin Immunoprecipitation; CpG Islands; DNA Methylation; Female; Genetic Predisposition to Disease; Histones; Humans; Lysine; Male; Methylation; Oligonucleotide Array Sequence Analysis; Promoter Regions, Genetic; Prostatic Neoplasms; Protein Binding; RNA Polymerase II; Transcription, Genetic

2009
Polymorphisms of the prion protein gene (PRNP) in a Serbian population.
    The International journal of neuroscience, 2010, Volume: 120, Issue:7

    Topics: Amino Acid Substitution; Female; Genetic Predisposition to Disease; Genetic Testing; Glutamic Acid; Humans; Lysine; Male; Mutagenesis, Insertional; Oligopeptides; Polymorphism, Genetic; Prion Diseases; Prion Proteins; Prions; Repetitive Sequences, Amino Acid; Sequence Deletion; Serbia

2010
Genetic Creutzfeldt-Jakob disease associated with the E200K mutation: characterization of a complex proteinopathy.
    Acta neuropathologica, 2011, Volume: 121, Issue:1

    Topics: Amino Acid Substitution; Creutzfeldt-Jakob Syndrome; Female; Genetic Predisposition to Disease; Glutamic Acid; Humans; Lysine; Male; Middle Aged; Prion Proteins; Prions

2011
Hereditary cerebral hemorrhage with amyloidosis associated with the E693K mutation of APP.
    Archives of neurology, 2010, Volume: 67, Issue:8

    Topics: Aged; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Amyloidosis, Familial; Apolipoprotein E4; Cerebral Hemorrhage; Family Health; Female; Gene Frequency; Genetic Predisposition to Disease; Genome-Wide Association Study; Genotype; Glutamic Acid; Humans; Italy; Lysine; Magnetic Resonance Imaging; Male; Middle Aged; Mutation; Peptide Fragments

2010
ENPP1/PC-1 K121Q and other predictors of posttransplant diabetes.
    Metabolic syndrome and related disorders, 2011, Volume: 9, Issue:1

    Topics: Adult; Age Factors; Amino Acid Substitution; Biomarkers; Diabetes Mellitus; Female; Genetic Predisposition to Disease; Glutamic Acid; Humans; Lysine; Male; Middle Aged; Phosphoric Diester Hydrolases; Polymorphism, Single Nucleotide; Prognosis; Pyrophosphatases; Racial Groups; Transplantation

2011
The ENPP1 K121Q polymorphism is not associated with type 2 diabetes and related metabolic traits in an Iranian population.
    Molecular and cellular biochemistry, 2011, Volume: 350, Issue:1-2

    Topics: Adult; Aged; Amino Acid Substitution; Diabetes Mellitus, Type 2; Female; Gene Frequency; Genetic Predisposition to Disease; Genetics, Population; Genotype; Glutamic Acid; Humans; Insulin Resistance; Iran; Lysine; Male; Metabolic Diseases; Middle Aged; Phosphoric Diester Hydrolases; Polymorphism, Single Nucleotide; Pyrophosphatases; Young Adult

2011
Naturally occurring FCER1A N222K mutation - its ethnicity-dependent distribution and a role in atopic dermatitis.
    Molecular immunology, 2011, Volume: 48, Issue:8

    Topics: Alleles; Amino Acid Substitution; Animals; Asian People; Aspartic Acid; Asthma; Dermatitis, Atopic; Gene Frequency; Genetic Predisposition to Disease; Genotype; Humans; Lysine; Mutagenesis, Site-Directed; Mutation; Polymorphism, Single Nucleotide; Rats; Receptors, IgE; White People

2011
The missense variation Q705K in CIAS1/NALP3/NLRP3 gene and an NLRP1 haplotype are associated with celiac disease.
    The American journal of gastroenterology, 2011, Volume: 106, Issue:3

    Topics: Adaptor Proteins, Signal Transducing; Adolescent; Apoptosis Regulatory Proteins; Carrier Proteins; Celiac Disease; Child; Child, Preschool; Female; Genetic Predisposition to Disease; Genotype; Glutamine; Haplotypes; Humans; Inflammasomes; Italy; Lysine; Male; Mutation, Missense; NLR Family, Pyrin Domain-Containing 3 Protein; NLR Proteins; Polymorphism, Single Nucleotide

2011
JAK2V617F mutation is associated with special alleles in essential thrombocythemia.
    Leukemia & lymphoma, 2011, Volume: 52, Issue:3

    Topics: Alleles; Amino Acid Substitution; DNA Mutational Analysis; Gene Frequency; Genetic Linkage; Genetic Predisposition to Disease; Genetic Testing; Humans; Janus Kinase 2; Leucine; Lysine; Mutation, Missense; Phenylalanine; Polymorphism, Single Nucleotide; Receptors, Thrombopoietin; Thrombocythemia, Essential; Tryptophan; Valine

2011
Reduced cortical thickness is associated with the glutamatergic regulatory gene risk variant DAOA Arg30Lys in schizophrenia.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2011, Volume: 36, Issue:8

    Topics: Adult; Arginine; Carrier Proteins; Cerebral Cortex; Female; Genetic Association Studies; Genetic Predisposition to Disease; Genetic Variation; Glutamic Acid; Humans; Intracellular Signaling Peptides and Proteins; Lysine; Male; Polymorphism, Genetic; Schizophrenia; Young Adult

2011
Schizophrenia with the 22q11.2 deletion and additional genetic defects: case history.
    The British journal of psychiatry : the journal of mental science, 2011, Volume: 199, Issue:3

    Topics: Adult; Arginine; Chromosome Deletion; Chromosomes, Human, Pair 22; DiGeorge Syndrome; Exotropia; Female; Frameshift Mutation; Genetic Predisposition to Disease; Homeodomain Proteins; Humans; Lactoylglutathione Lyase; Lysine; Polymerase Chain Reaction; Schizophrenia; Transcription Factors

2011
Association of XRCC1, XRCC3, and NAT2 polymorphisms with the risk of oral submucous fibrosis among eastern Indian population.
    Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology, 2012, Volume: 41, Issue:4

    Topics: Adult; Areca; Arginine; Arylamine N-Acetyltransferase; Case-Control Studies; Codon; DNA Repair; DNA-Binding Proteins; Female; Genetic Predisposition to Disease; Glutamic Acid; Glutamine; Glycine; Heterozygote; Homozygote; Humans; India; Lysine; Male; Methionine; Multifactor Dimensionality Reduction; Oral Submucous Fibrosis; Polymorphism, Genetic; Polymorphism, Restriction Fragment Length; Polymorphism, Single Nucleotide; Risk Factors; Threonine; Tobacco, Smokeless; Tryptophan; X-ray Repair Cross Complementing Protein 1

2012
Association of K832R and R952K SNPs of Wilson's disease gene with Alzheimer's disease.
    Journal of Alzheimer's disease : JAD, 2012, Volume: 29, Issue:4

    Topics: Adenosine Triphosphatases; Aged; Aged, 80 and over; Alzheimer Disease; Arginine; Cation Transport Proteins; Copper-Transporting ATPases; Female; Genetic Association Studies; Genetic Predisposition to Disease; Genotype; Humans; Linkage Disequilibrium; Logistic Models; Lysine; Male; Middle Aged; Polymorphism, Single Nucleotide

2012
Association between three genetic polymorphisms of glutathione S-transferase Z1 (GSTZ1) and susceptibility to bipolar disorder.
    Psychiatry research, 2012, Jun-30, Volume: 198, Issue:1

    Topics: Adolescent; Adult; Age Factors; Bipolar Disorder; Chi-Square Distribution; DNA Mutational Analysis; Female; Gene Frequency; Genetic Predisposition to Disease; Genotype; Glutamic Acid; Glutathione Transferase; Humans; Linkage Disequilibrium; Logistic Models; Lysine; Male; Middle Aged; Polymorphism, Single Nucleotide; Young Adult

2012
Prolonged incubation time in sheep with prion protein containing lysine at position 171.
    Journal of veterinary diagnostic investigation : official publication of the American Association of Veterinary Laboratory Diagnosticians, Inc, 2012, Volume: 24, Issue:3

    Topics: Animals; Blotting, Western; Brain; Codon; Genetic Predisposition to Disease; Genotype; Immunohistochemistry; Lysine; Polymorphism, Genetic; Prions; Scrapie; Sheep

2012
The MBD4 Glu346Lys polymorphism is associated with the risk of cervical cancer in a Chinese population.
    International journal of gynecological cancer : official journal of the International Gynecological Cancer Society, 2012, Volume: 22, Issue:9

    Topics: Adult; Aged; Aged, 80 and over; Amino Acid Substitution; Asian People; Carcinoma, Squamous Cell; Case-Control Studies; Endodeoxyribonucleases; Female; Genetic Association Studies; Genetic Predisposition to Disease; Genetics, Population; Glutamine; Humans; Lysine; Middle Aged; Mutation, Missense; Polymorphism, Restriction Fragment Length; Polymorphism, Single Nucleotide; Uterine Cervical Neoplasms

2012
Aberrant patterns of H3K4 and H3K27 histone lysine methylation occur across subgroups in medulloblastoma.
    Acta neuropathologica, 2013, Volume: 125, Issue:3

    Topics: Base Sequence; Cerebellar Neoplasms; Cohort Studies; DNA-Binding Proteins; Female; Genetic Predisposition to Disease; Genome; Histone Demethylases; Histone Methyltransferases; Histone-Lysine N-Methyltransferase; Humans; Lysine; Male; Medulloblastoma; Methylation; Mutation; Neoplasm Proteins; Nuclear Proteins; Polymorphism, Single Nucleotide

2013
Major differences in antigen-processing correlate with a single Arg71<-->Lys substitution in HLA-DR molecules predisposing to rheumatoid arthritis and with their selective interactions with 70-kDa heat shock protein chaperones.
    Journal of immunology (Baltimore, Md. : 1950), 2002, Sep-15, Volume: 169, Issue:6

    Topics: Amino Acid Substitution; Animals; Antigen Presentation; Arginine; Arthritis, Rheumatoid; Clone Cells; Epitopes, T-Lymphocyte; Escherichia coli Proteins; Genetic Predisposition to Disease; HLA-DR Antigens; HSP70 Heat-Shock Proteins; Humans; Hybridomas; Leukemia P388; Lysine; Mice; Protein Subunits; Receptors, Cholinergic; Recombinant Proteins; T-Lymphocytes; Transfection; Tumor Cells, Cultured

2002
Myocyte production of nitric oxide in response to AChR-reactive antibodies in two inbred rat strains may influence disease outcome in experimental myasthenia gravis.
    Clinical immunology (Orlando, Fla.), 2003, Volume: 106, Issue:2

    Topics: Animals; Antibody Specificity; Autoantibodies; Cells, Cultured; Clone Cells; Enzyme Induction; Enzyme Inhibitors; Female; Genetic Predisposition to Disease; Immunization, Passive; Lysine; Muscle Proteins; Muscle, Skeletal; Myasthenia Gravis, Autoimmune, Experimental; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Rats; Rats, Inbred Lew; Rats, Inbred WF; Receptors, Cholinergic; RNA, Messenger; Torpedo

2003
[Correlation analysis between WNK4 gene and essential hypertension].
    Zhongguo yi xue ke xue yuan xue bao. Acta Academiae Medicinae Sinicae, 2003, Volume: 25, Issue:2

    Topics: Adult; Brain; Female; Gene Expression; Gene Frequency; Genes; Genetic Predisposition to Disease; Humans; Hypertension; Kidney; Lysine; Male; Middle Aged; Mutation; Phenotype; Protein Serine-Threonine Kinases; RNA, Messenger

2003
The M98K variant of the OPTINEURIN (OPTN) gene modifies initial intraocular pressure in patients with primary open angle glaucoma.
    Journal of medical genetics, 2003, Volume: 40, Issue:11

    Topics: Amino Acid Substitution; Cell Cycle Proteins; Eye Proteins; Genetic Predisposition to Disease; Genetic Variation; Genotype; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Lysine; Membrane Transport Proteins; Methionine; Nerve Tissue Proteins; Transcription Factor TFIIIA

2003
Genetic polymorphism PC-1 K121Q and ethnic susceptibility to insulin resistance.
    The Journal of clinical endocrinology and metabolism, 2003, Volume: 88, Issue:12

    Topics: Adult; Asian People; Female; Gene Frequency; Genetic Predisposition to Disease; Glucose Clamp Technique; Glucose Tolerance Test; Glutamine; Humans; Hyperinsulinism; India; Insulin Resistance; Lysine; Male; Middle Aged; Phosphoric Diester Hydrolases; Polymorphism, Genetic; Pyrophosphatases; White People

2003
Susceptibility to pre-eclampsia in Finnish women is associated with R485K polymorphism in the factor V gene, not with Leiden mutation.
    European journal of human genetics : EJHG, 2004, Volume: 12, Issue:3

    Topics: Arginine; Factor V; Female; Finland; Genetic Predisposition to Disease; Humans; Lysine; Mutation; Polymorphism, Genetic; Pre-Eclampsia; Pregnancy

2004
Susceptibility to primary sclerosing cholangitis is associated with polymorphisms of intercellular adhesion molecule-1.
    Journal of hepatology, 2004, Volume: 40, Issue:3

    Topics: Alleles; Arginine; Case-Control Studies; Cholangitis, Sclerosing; Cohort Studies; Gene Frequency; Genetic Predisposition to Disease; Genotype; Glutamic Acid; Glycine; Haplotypes; HLA Antigens; Homozygote; Humans; Intercellular Adhesion Molecule-1; Lysine; Polymorphism, Genetic; Primed In Situ Labeling

2004
A M55V polymorphism in a novel SUMO gene (SUMO-4) differentially activates heat shock transcription factors and is associated with susceptibility to type I diabetes mellitus.
    The Journal of biological chemistry, 2004, Jun-25, Volume: 279, Issue:26

    Topics: Amino Acid Sequence; Amino Acid Substitution; Cell Line; Diabetes Mellitus, Type 1; Genes, Reporter; Genetic Predisposition to Disease; Heat-Shock Proteins; Humans; Lysine; Methionine; Molecular Sequence Data; NF-kappa B; Oxidative Stress; Polymorphism, Genetic; Recombinant Proteins; Sequence Alignment; Small Ubiquitin-Related Modifier Proteins; Tissue Distribution; Transcription Factors; Valine

2004
Association of aldehyde dehydrogenase-2 polymorphism with alcoholic polyneuropathy in humans.
    Neuroscience letters, 2004, Jun-17, Volume: 363, Issue:3

    Topics: Action Potentials; Alcoholic Neuropathy; Aldehyde Dehydrogenase; Aldehyde Dehydrogenase, Mitochondrial; Case-Control Studies; Female; Gene Frequency; Genetic Predisposition to Disease; Genotype; Glutamic Acid; Humans; Lysine; Male; Middle Aged; Neural Conduction; Peripheral Nerves; Polymorphism, Genetic; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger

2004
Colonic adenomas do not cosegregate with the I1307K APC missense mutation in an Israeli non-Ashkenazi family.
    Digestive diseases and sciences, 2005, Volume: 50, Issue:1

    Topics: Adenoma; Adenomatous Polyposis Coli; Aged; Chromosome Segregation; Colonic Neoplasms; Female; Genes, APC; Genetic Predisposition to Disease; Humans; Isoleucine; Israel; Jews; Lysine; Male; Middle Aged; Mutation, Missense; Pedigree

2005
Association of micropenis with Pro185Ala polymorphism of the gene for aryl hydrocarbon receptor repressor involved in dioxin signaling.
    Endocrine journal, 2005, Volume: 52, Issue:1

    Topics: Adolescent; Alanine; Arginine; Basic Helix-Loop-Helix Transcription Factors; Case-Control Studies; Child; Child, Preschool; Congenital Abnormalities; Dioxins; Gene Frequency; Genetic Predisposition to Disease; Humans; Infant; Infant, Newborn; Lysine; Male; Penis; Polymorphism, Genetic; Proline; Receptors, Aryl Hydrocarbon; Repressor Proteins; Signal Transduction

2005
Plasma cell membrane glycoprotein-1 K121Q polymorphism in preeclampsia.
    Gynecologic and obstetric investigation, 2006, Volume: 61, Issue:3

    Topics: Adult; Case-Control Studies; Female; Finland; Gene Frequency; Genetic Markers; Genetic Predisposition to Disease; Genotype; Glutamine; Humans; Lysine; Phosphoric Diester Hydrolases; Polymorphism, Genetic; Pre-Eclampsia; Pregnancy; Pyrophosphatases

2006
Gender-specific association of ATP-binding cassette transporter 1 (ABCA1) polymorphisms with the risk of late-onset Alzheimer's disease.
    Neurobiology of aging, 2007, Volume: 28, Issue:6

    Topics: Adaptor Proteins, Signal Transducing; Aged; Alzheimer Disease; Apolipoprotein E4; Arginine; ATP Binding Cassette Transporter 1; ATP-Binding Cassette Transporters; Autophagy-Related Proteins; Carrier Proteins; Cell Cycle Proteins; Female; Gene Frequency; Genetic Predisposition to Disease; Genotype; Humans; Linkage Disequilibrium; Logistic Models; Lysine; Male; Polymorphism, Genetic; Sex Characteristics

2007
Fatal hypertrophic cardiomyopathy and nemaline myopathy associated with ACTA1 K336E mutation.
    Neuromuscular disorders : NMD, 2006, Volume: 16, Issue:9-10

    Topics: Actinin; Actins; Amino Acid Substitution; Cardiomyopathy, Hypertrophic, Familial; Child, Preschool; DNA Mutational Analysis; Fatal Outcome; Genetic Predisposition to Disease; Genetic Testing; Glutamic Acid; Humans; Lysine; Male; Muscle Contraction; Muscle Fibers, Skeletal; Muscle, Skeletal; Mutation, Missense; Myocardium; Myopathies, Nemaline

2006
Novel features in a patient homozygous for the L347P mutation in the PINK1 gene.
    Parkinsonism & related disorders, 2007, Volume: 13, Issue:6

    Topics: Adult; Aged; Aged, 80 and over; Cohort Studies; DNA Mutational Analysis; Female; Gene Frequency; Genetic Predisposition to Disease; Homozygote; Humans; Lysine; Male; Middle Aged; Mutation; Parkinson Disease; Proline; Protein Kinases

2007
The K469E polymorphism of the intracellular adhesion molecule 1 (ICAM-1) gene is not associated with myocardial infarction in Caucasians with type 2 diabetes.
    Folia biologica, 2006, Volume: 52, Issue:3

    Topics: Aged; Case-Control Studies; Diabetes Mellitus, Type 2; Female; Genetic Predisposition to Disease; Genotype; Glutamine; Humans; Intercellular Adhesion Molecule-1; Lysine; Male; Middle Aged; Myocardial Infarction; Polymorphism, Single Nucleotide; White People

2006
Novel SOD1 N86K mutation is associated with a severe phenotype in familial ALS.
    Muscle & nerve, 2007, Volume: 36, Issue:1

    Topics: Amyotrophic Lateral Sclerosis; Asparagine; DNA Mutational Analysis; Family Health; Female; Genetic Predisposition to Disease; Humans; Lysine; Middle Aged; Mutation; Phenotype; Superoxide Dismutase; Superoxide Dismutase-1

2007
Variants in the LRRK1 gene and susceptibility to Parkinson's disease in Norway.
    Neuroscience letters, 2007, Apr-18, Volume: 416, Issue:3

    Topics: Adult; Aged; Aged, 80 and over; Case-Control Studies; DNA Mutational Analysis; Female; Gene Frequency; Genetic Predisposition to Disease; Genotype; Glutamic Acid; Humans; Lysine; Male; Middle Aged; Norway; Parkinson Disease; Polymorphism, Genetic; Protein Serine-Threonine Kinases

2007
Glucocorticoid receptor gene polymorphisms associated with more aggressive disease phenotype in MS.
    Journal of neuroimmunology, 2007, Volume: 186, Issue:1-2

    Topics: Adult; Arginine; DNA Mutational Analysis; Female; Gene Frequency; Genetic Predisposition to Disease; Genotype; Humans; Lysine; Magnetic Resonance Imaging; Male; Middle Aged; Multiple Sclerosis; Odds Ratio; Phenotype; Polymorphism, Genetic; Receptors, Glucocorticoid

2007
Polymorphisms in XPD (Asp312Asn and Lys751Gln) genes, sunburn and arsenic-related skin lesions.
    Carcinogenesis, 2007, Volume: 28, Issue:8

    Topics: Adult; Amino Acid Substitution; Arsenic; Asparagine; Aspartic Acid; Case-Control Studies; Female; Genetic Predisposition to Disease; Glutamine; Humans; Lysine; Male; Polymorphism, Single Nucleotide; Skin Diseases; Sunburn; Water Supply; Xeroderma Pigmentosum Group D Protein

2007
Association analysis of gamma2 subunit of gamma-aminobutyric acid (GABA) type A receptor and voltage-gated sodium channel type II alpha-polypeptide gene mutation in southern Chinese children with febrile seizures.
    Journal of child neurology, 2007, Volume: 22, Issue:6

    Topics: Arginine; Chi-Square Distribution; Child; Child, Preschool; China; DNA Mutational Analysis; Female; Gene Frequency; Genetic Predisposition to Disease; Genotype; Humans; Infant; Lysine; Male; Methionine; Mutation; NAV1.2 Voltage-Gated Sodium Channel; Nerve Tissue Proteins; Polymorphism, Single Nucleotide; Receptors, GABA-A; Seizures, Febrile; Sodium Channels; Tryptophan

2007
Mechanism of age-dependent susceptibility and novel treatment strategy in glutaric acidemia type I.
    The Journal of clinical investigation, 2007, Volume: 117, Issue:11

    Topics: Aging; Amino Acid Metabolism, Inborn Errors; Animals; Brain Diseases, Metabolic, Inborn; Child; Diet; Disease Models, Animal; gamma-Aminobutyric Acid; Genetic Predisposition to Disease; Glucose; Glutamic Acid; Glutarates; Glutaryl-CoA Dehydrogenase; Homoarginine; Humans; Lysine; Mice; Mice, Knockout; Mitochondria; Neurons; Nuclear Magnetic Resonance, Biomolecular; Tryptophan

2007
Combination of cardiac conduction disease and long QT syndrome caused by mutation T1620K in the cardiac sodium channel.
    Cardiovascular research, 2008, Mar-01, Volume: 77, Issue:4

    Topics: Action Potentials; Adolescent; Adult; Ajmaline; Animals; Anti-Arrhythmia Agents; Bundle-Branch Block; Cell Line; Child; Death, Sudden, Cardiac; DNA Mutational Analysis; Electrocardiography; Female; Gene Transfer Techniques; Genetic Predisposition to Disease; Humans; Kinetics; Lidocaine; Long QT Syndrome; Lysine; Male; Muscle Proteins; Mutation; Myocardium; NAV1.5 Voltage-Gated Sodium Channel; Patch-Clamp Techniques; Pedigree; Sodium; Sodium Channels; Syncope; Threonine; Xenopus laevis

2008
A novel polymorphism, E254K, in the 5-lipoxygenase gene associated with bronchial asthma.
    International journal of molecular medicine, 2008, Volume: 21, Issue:2

    Topics: Arachidonate 5-Lipoxygenase; Asthma; Base Sequence; Child; DNA Mutational Analysis; Female; Gene Expression Regulation, Enzymologic; Gene Frequency; Genetic Predisposition to Disease; Glutamic Acid; Humans; Ionomycin; Leukotriene B4; Leukotriene E4; Lysine; Male; Models, Molecular; Molecular Sequence Data; Neutrophils; Polymorphism, Genetic; RNA, Messenger; Structural Homology, Protein

2008
A successfully treated adult patient with L-2-hydroxyglutaric aciduria.
    Neurology, 2008, Mar-25, Volume: 70, Issue:13

    Topics: Adult; Age Factors; Alcohol Oxidoreductases; Brain; Brain Diseases, Metabolic; Brain Diseases, Metabolic, Inborn; Carnitine; Chromosomes, Human, Pair 14; Female; Flavin-Adenine Dinucleotide; Genetic Markers; Genetic Predisposition to Disease; Homozygote; Humans; Intellectual Disability; Lysine; Magnetic Resonance Imaging; Movement Disorders; Treatment Outcome

2008
Investigation of tRNA(Leu/Lys) and ATPase 6 genes mutations in Huntington's disease.
    Cellular and molecular neurobiology, 2008, Volume: 28, Issue:7

    Topics: Adenosine Triphosphatases; Amino Acid Substitution; DNA Damage; DNA Mutational Analysis; DNA, Mitochondrial; Genetic Predisposition to Disease; Genetic Testing; Humans; Huntington Disease; Leucine; Lysine; Mitochondrial Diseases; Mutation; RNA, Transfer

2008
Inducible nitric oxide synthase (iNOS) is not required for IL-2-induced hypotension and vascular leak syndrome in mice.
    Journal of immunotherapy (Hagerstown, Md. : 1997), 2008, Volume: 31, Issue:4

    Topics: Animals; Capillary Leak Syndrome; Capillary Permeability; Genetic Predisposition to Disease; Hypotension; Interferon-gamma; Interleukin-2; Lysine; Manganese; Mice; Mice, Inbred C3H; Mice, Inbred C57BL; Mice, Knockout; Nitric Oxide; Nitric Oxide Synthase Type II; omega-N-Methylarginine; Organometallic Compounds

2008
Grouping HLA-B locus serologic specificities according to shared structural motifs suggests that different peptide-anchoring pockets may have contrasting influences on the course of HIV-1 infection.
    Human immunology, 1995, Volume: 42, Issue:1

    Topics: Adult; AIDS-Related Opportunistic Infections; Antigen Presentation; Binding Sites; CD4 Lymphocyte Count; CD8-Positive T-Lymphocytes; Child; Disease Progression; Disease Susceptibility; Gene Frequency; Genetic Predisposition to Disease; HIV Infections; HIV-1; HLA-B Antigens; HLA-B35 Antigen; Humans; Lymphocyte Count; Lysine; Peptide Fragments; Protein Binding; Protein Conformation

1995
Polymorphisms in the DNA repair gene XPD: correlations with risk and age at onset of basal cell carcinoma.
    Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, 1999, Volume: 8, Issue:1

    Topics: Adenine; Adult; Age Factors; Age of Onset; Alleles; Carcinoma, Basal Cell; Confidence Intervals; Cytosine; DNA Helicases; DNA Repair; DNA-Binding Proteins; Exons; Female; Genetic Predisposition to Disease; Genetic Variation; Genotype; Glutamine; Humans; Lysine; Male; Middle Aged; Polymerase Chain Reaction; Polymorphism, Genetic; Proteins; Psoriasis; Risk Factors; Transcription Factors; Transcription, Genetic; Xeroderma Pigmentosum Group D Protein

1999
Inhibition of inducible nitric oxide synthase exacerbates chronic cerebral toxoplasmosis in Toxoplasma gondii-susceptible C57BL/6 mice but does not reactivate the latent disease in T. gondii-resistant BALB/c mice.
    Journal of immunology (Baltimore, Md. : 1950), 1999, Mar-15, Volume: 162, Issue:6

    Topics: Administration, Oral; Animals; Brain; Chronic Disease; Encephalitis; Enzyme Induction; Enzyme Inhibitors; Female; Genetic Predisposition to Disease; Immunity, Innate; Kinetics; Lysine; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Species Specificity; Toxoplasma; Toxoplasmosis, Animal; Toxoplasmosis, Cerebral

1999
Risk estimation and value-of-information analysis for three proposed genetic screening programs for chronic beryllium disease prevention.
    Risk analysis : an official publication of the Society for Risk Analysis, 2000, Volume: 20, Issue:1

    Topics: Berylliosis; Chronic Disease; Cohort Studies; Cost of Illness; Environmental Exposure; Ethics, Medical; Forecasting; Genetic Markers; Genetic Predisposition to Disease; Genetic Testing; Genetic Variation; Glutamic Acid; Health Expenditures; HLA-DP Antigens; Humans; Jurisprudence; Lysine; Occupational Exposure; Polymorphism, Genetic; Prevalence; Probability; Risk Assessment; Risk Management; Sensitivity and Specificity; Social Values

2000
The effects of NO synthase inhibitors on murine collagen-induced arthritis do not support a role of NO in the protective effect of IFN-gamma.
    Journal of leukocyte biology, 2000, Volume: 68, Issue:1

    Topics: Administration, Oral; Animals; Arthritis, Rheumatoid; Autoantibodies; Autoimmune Diseases; Collagen; Disease Models, Animal; Dose-Response Relationship, Drug; Enzyme Inhibitors; Female; Genetic Predisposition to Disease; Guanidines; Interferon gamma Receptor; Interferon-gamma; Lysine; Male; Mice; Mice, Inbred DBA; Mice, Knockout; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitrites; Receptors, Interferon; Weight Loss

2000
A novel mutation E179K of the MEN1 gene predisposes for multiple endocrine neoplasia-type 1 (MEN1).
    Human mutation, 2000, Volume: 16, Issue:6

    Topics: Adenoma; Adolescent; Adult; Amino Acid Substitution; Diabetes Mellitus, Type 2; Genetic Predisposition to Disease; Glutamic Acid; Humans; Hyperinsulinism; Hyperparathyroidism; Insulinoma; Lysine; Male; Multiple Endocrine Neoplasia Type 1; Mutation, Missense; Nuclear Family; Pancreatic Neoplasms

2000
Prothrombin Scranton: substitution of an amino acid residue involved in the binding of Na+ (LYS-556 to THR) leads to dysprothrombinemia.
    Thrombosis and haemostasis, 2001, Volume: 85, Issue:4

    Topics: Adolescent; Amino Acid Substitution; Exons; Female; Genetic Predisposition to Disease; Genotype; Humans; Lysine; Male; Mutation, Missense; Pedigree; Polymerase Chain Reaction; Prothrombin; Sequence Analysis, DNA; Sodium; Structure-Activity Relationship

2001
Beryllium binding to HLA-DP molecule carrying the marker of susceptibility to berylliosis glutamate beta 69.
    Human immunology, 2001, Volume: 62, Issue:7

    Topics: Amino Acid Sequence; Amino Acid Substitution; Animals; Berylliosis; Beryllium; Biomarkers; Cell Line; Drosophila melanogaster; Genetic Predisposition to Disease; Genetic Vectors; Glutamic Acid; HLA-DP Antigens; Humans; Lysine; Molecular Sequence Data; Mutagenesis, Site-Directed; Protein Binding; Solubility

2001